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| 1 | Multicenter study of endoscopic preoperative biliary drainage for malignant distal biliary obstruction显示文摘AIM: To determine the optimal method of endoscopic preoperative biliary drainage for malignant distal biliary obstruction.METHODS: Multicenter retrospective study was conducted in patients who underwent plastic stent(PS) or nasobiliary catheter(NBC) placement for resectable malignant distal biliary obstruction followed by surgery between January 2010 and March 2012. Procedurerelated adverse events, stent/catheter dysfunction(occlusion or migration of PS/NBC, developmentof cholangitis, or other conditions that required repeat endoscopic biliary intervention), and jaundice resolution(bilirubin level < 3.0 mg/d L) were evaluated. Cumulative incidence of jaundice resolution and dysfunction of PS/NBC were estimated using competing risk analysis. Patient characteristics and preoperative biliary drainage were also evaluated for association with the time to jaundice resolution and PS/NBC dysfunction using competing risk regression analysis.RESULTS: In total, 419 patients were included in the study(PS, 253 and NBC, 166). Primary cancers included pancreatic cancer in 194 patients(46%), bile duct cancer in 172(41%), gallbladder cancer in three(1%), and ampullary cancer in 50(12%). The median serum total bilirubin was 7.8 mg/d L and 324 patients(77%) had ≥ 3.0 mg/d L. During the median time to surgery of 29 d [interquartile range(IQR), 30-39 d]. PS/NBC dysfunction rate was 35% for PS and 18% for NBC [Subdistribution hazard ratio(SHR) = 4.76; 95%CI: 2.44-10.0, P < 0.001]; the pig-tailed tip was a risk factor for PS dysfunction. Jaundice resolution was achieved in 85% of patients and did not depend on the drainage method(PS or NBC).CONCLUSION: PS has insufficient patency for preoperative biliary drainage. Given the drawbacks of external drainage via NBC, an alternative method of internal drainage should be explored. | Naoki Sasahira Tsuyoshi Hamada Osamu Togawa Ryuichi Yamamoto Tomohisa Iwai Kiichi Tamada Yoshiaki Kawaguchi Kenji Shimura Takero Koike Yu Yoshida Kazuya Sugimori Shomei Ryozawa Toshiharu Kakimoto Ko Nishikawa Katsuya Kitamura Tsunao Imamura Masafumi Mizuide Nobuo Toda Iruru Maetani Yuji Sakai Takao Itoi Masatsugu Nagahama Yousuke Nakai Hiroyuki Isayama | 2016 | World Journal of Gastroenterology2016，22，14： | 18 |
| 2 | Clinical significance of global two-dimensional strain as a surrogate parameter of myocardial fibrosis and cardiac events in patients with hypertrophic cardiomyopathy显示文摘 | Makoto Saito Hideki Okayama Toyofumi Yoshii Haruhiko Higashi Hiroe Morioka Go Hiasa Takumi Sumimoto Shinji Inaba Kazuhisa Nishimura Katsuji Inoue Akiyoshi Ogimoto Yuji Shigematsu Mareomi Hamada Jitsuo Higaki | 2012 | European Heart Journal – Cardiovascular Imaging2012，，7： | 1 |
| 3 | White organic electroluminescent devices显示文摘 | HAMADA Yuji SAND Takashi | 1996 | Appl Phys Lett1996，68，： | 1 |
| 4 | 显示文摘 | Yuji Hamada Takeshi Sano Masayuki Fujita | 1993 | Jpn J Appl Phys1993，32，： | 1 |
| 5 | Clinical features of isolated noncompaction of the ventricular myocardium显示文摘 | Fukiko Ichida Yuji Hamamichi Toshio Miyawaki Yasuo Ono Tetsuro Kamiya Teiji Akagi Hiromichi Hamada Osamu Hirose Takeshi Isobe Katsuhiko Yamada Shunji Kurotobi Hiroshi Mito Toshiharu Miyake Yasuo Murakami Takeshi Nishi Makoto Shinohara Masashi Seguchi Shin | 1999 | Journal of the American College of Cardiology1999，，1： | 1 |
| 6 | EpCAM contributes to formation of functional tight junction in the intestinal epithelium by recruiting claudin proteins显示文摘 | Zili Lei Takako Maeda Atsushi Tamura Tetsuya Nakamura Yuji Yamazaki Hidetaka Shiratori Kenta Yashiro Sachiko Tsukita Hiroshi Hamada | 2012 | Developmental Biology2012，，2： | 1 |
| 7 | Development of OLED with high stability and luminance effi-ciency by codoping methods for full color displays显示文摘 | Hiroshi Kanno Yuji Hamada Hisakazu Takahashi | 2004 | IEEE Journal of Selected Topics in Quantum Electronics2004，10，1： | 1 |
| 8 | Blood Pressure Response to the Valsalva Maneuver in Pheochromocytoma and Pseudopheochromocytoma显示文摘 | Mareomi Hamada Yuji Shigematsu Mikio Mukai Yukio Kazatani Tatsuo Kokubu Kunio Hiwada | 1995 | Hypertension1995，，2： | 1 |
| 9 | Association of abnormal diurnal blood pressure variation with the development of silent cerebral infarction in patients with late-life-onset depression显示文摘 | Tetsuhito Murata Tetsuya Takahashi Masao Omori Yuji Wada Toshihiko Hamada Haruyoshi Yoshida | 2003 | General Hospital Psychiatry2003，，4： | 1 |
| 10 | De velopment of OLED with high stability and luminance efficiency by co-doping methods for full color displays 显示文摘 | Hiroshi Kanno Yuji Hamada Hisakazu Takahashi | 2004 | IEEE Journal of Selected Topic in Quantum Elec- tronics2004，10，1： | 1 |
| 11 | Clinical features of isolated noncompaction of the ventricular myocardium显示文摘 | Fukiko Ichida Yuji Hamamichi Toshio Miyawaki Yasuo Ono Tetsuro Kamiya Teiji Akagi Hiromichi Hamada Osamu Hirose Takeshi Isobe Katsuhiko Yamada Shunji Kurotobi Hiroshi Mito Toshiharu Miyake Yasuo Murakami Takeshi Nishi Makoto Shinohara Masashi Seguchi Shin | 1999 | Journal of the American College of Cardiology1999，，1： | 1 |
| 12 | Left ventricular hypertrophy precedes other target-organ damagein primary aldosteronism显示文摘 | Yuji Shigematsu Mareomi Hamada Hideki Okayama | 1997 | Hypertension1997，29，： | 1 |
| 13 | Blue electroluminescence in thin films of azomethin-zinc complexes显示文摘 | Yuji Hamada Takeshi Sano Masayuki Fujita | 1993 | Jpn J Appl Phys1993，32，： | 1 |
| 14 | Organic electroluminescent divices with 8-hydroxyquinoline derivative metal complexes as an emitter显示文摘 | Sano Takeshi Fujita Masayuki | 1993 | Jpn Appl Phys(Parts)1993，32，2： | 1 |
| 15 | Ischemia of the intestinal mucosa during cardiopulmonary bypass显示文摘 | Nobuo Tsunooka Yoshihiro Hamada Hiroshi Imagawa Yoshitsugu Nakamura Takahiro Shiozaki Hideaki Suzuki Hiroyuki Kikkawa Katsutoshi Miyauchi Yuji Watanabe Kanji Kawachi | 2003 | Journal of Artificial Organs2003，，2： | 1 |
| 16 | White light emitting material for organic electroluminescent devices显示文摘 | Hamada Yuji Sano Takeshi Fujii Hiroyuki | 1996 | Jpn J Appl Phys1996，35，10： | 1 |
| 17 | Whitelight-emitting material for organic electroluminescent devices显示文摘 | Yuji Hamada Takeshi Sano Hiroyuki Fujii | 1996 | Jpn J Appl Lett1996，35，： | 1 |
| 18 | Blood Pressure Response to the Valsalva Maneuver in Pheochromocytoma and Pseudopheochromocytoma显示文摘 | Mareomi Hamada Yuji Shigematsu Mikio Mukai Yukio Kazatani Tatsuo Kokubu Kunio Hiwada | 1995 | Hypertension1995，，2： | 1 |
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