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| 1 | Suppression of m6A reader Ythdf2 promotes hematopoietic stem cell expansion显示文摘 | Zhenrui Li Pengxu Qian Wanqing Shao Hailing Shi Xi C. He Madelaine Gogol Zulin Yu Yongfu Wang Meijie Qi Yunfei Zhu John M. Perry Kai Zhang Fang Tao Kun Zhou Deqing Hu Yingli Han Chongbei Zhao Richard Alexander Hanzhang Xu Shiyuan Chen Allison Peak Kathyrn Hall Michael Peterson Anoja Perera Jeffrey S. Haug Tari Parmely Hua Li Bin Shen Julia Zeitlinger Chuan He Linheng Li | 2018 | Cell Research2018，28，9： | 18 |
| 2 | Tomato SlAN11 regulates flavonoid biosynthesis and seed dormancy by interaction with bHLH proteins but not with MYB proteins显示文摘The flavonoid compounds are important secondary metabolites with versatile human nutritive benefits and fulfill a multitude of functions during plant growth and development.The abundance of different flavonoid compounds are finely tuned with species-specific pattern by a ternary MBW complex,which consists of a MYB,a bHLH,and a WD40 protein,but the essential role of SlAN11,which is a WD40 protein,is not fully understood in tomato until now.In this study,a tomato WD40 protein named as SlAN11 was characterized as an effective transcription regulator to promote plant anthocyanin and seed proanthocyanidin(PA)contents,with late flavonoid biosynthetic genes activated in 35S::SlAN11 transgenic lines,while the dihydroflavonol flow to the accumulation of flavonols or their glycosylated derivatives was reduced by repressing the expression of SlFLS in this SlAN11-overexpressed lines.The above changes were reversed in 35S::SlAN11-RNAi transgenic lines except remained levels of flavonol compounds and SlFLS expression.Interestingly,our data revealed that SlAN11 gene could affect seed dormancy by regulating the expressions of abscisic acid(ABA)signaling-related genes SlABI3 and SlABI5,and the sensitivity to ABA treatment in seed germination is conversely changed by SlAN11-overexpressed or-downregulated lines.Yeast two-hybrid assays demonstrated that SlAN11 interacted with bHLH but not with MYB proteins in the ternary MBW complex,whereas bHLH interacted with MYB in tomato.Our results indicated that low level of anthocyanins in tomato fruits,with low expression of bHLH(SlTT8)and MYB(SlANT1 and SlAN2)genes,remain unchanged upon modification of SlAN11 gene alone in the transgenic lines.These results suggest that the tomato WD40 protein SlAN11,coordinating with bHLH and MYB proteins,plays a crucial role in the fine adjustment of the flavonoid biosynthesis and seed dormancy in tomato. | Yongfeng Gao Jikai Liu Yongfu Chen Hai Tang Yang Wang Yongmei He Yongbin Ou Xiaochun Sun Songhu Wang Yinan Yao | 2018 | Horticulture Research2018，5，1： | 13 |
| 3 | Robust YAG:Ce single crystal for ultra-high efficiency laser lighting显示文摘At present,solid-state laser-driven lighting fabricated with blue laser diode(LD)and phosphor has been greatly developed in high-power lighting applications.The major obstacle is the luminescence saturation threshold of the fluorescence conversion material(YAG:Ce).In this work,we successfully prepared a series of high-quality and robust YAG:Ce single crystals.With high quantum efficiency(QE=92%),regular crystal structure and high thermal conductivity,the single-crystal has excellent ability to deal with high radiation flux and thermal accumulation generated by high power.Matching the single-crystal with the laser,the luminous efficiency up to 274 lm/W and saturation threshold of 12 W/mm^(2) were obtained.In addition,the influence of Ce doping concentration and sample processing conditions on the indicators in laser-driven white lighting was systematically studied.The results are of great significance and are believed to promote the development of solid-state laser-driven lighting. | Yaqian Zhang Jianming Liu Yujie Zhang Haisheng Yang Yanxia Yu Qingyun He Xiaojuan Liang Yongfu Liu Weidong Xiang | 2022 | Journal of Rare Earths2022，40，5： | 5 |
| 4 | High performance heterogeneous embedded computing: a review显示文摘As increasingly widening gap of computing demand and performance in embedded computing domain,heterogeneous computing architecture which delivers better performance as well as lower power in limited size is gaining more and more attention. At first,the heterogeneous computing model is presented. And the different tightly coupled single chip heterogeneous architectures and their application domain are introduced. Then,task partitioning methods are described. Several programming model technology are analyzed and discussed. Finally,main challenges and future perspective of High Performance Embedded Computing(HPEC) are summarized. | HE Yongfu WANG Shaojun PENG Yu | 2014 | Instrumentation2014，1，2： | 5 |
| 5 | Discrete energetic(~50-200 keV) electron events in the high-altitude cusp/polar cap/lobe显示文摘We identified 28 discrete electron events(DEEs) with enhanced fluxes at ~50-200 keV in the high-altitude cusp/polar cap/lobe,using the electron measurements by the BeiDa Image Electron Spectrometer(BD-IES) instrument onboard an inclined(55°)geosynchronous orbit(IGSO) satellite from October 2015 to January 2016. We find that among the 28 DEEs, 22 occur in the nightside and mostly in the northern cusp/polar cap/lobe, while 6 occur in the dayside and all in the southern cusp; 24 events correspond to an average interplanetary magnetic field(IMF) component B_z>0, 3 correspond to an average IMF B_z<0, and 1 has no OMNI IMF data. In these DEEs, the observed average omnidirectional electron differential flux generally fits well to a power-law spectrum, J^E^(-γ), with the spectral index y ranging from 2.6 to 4.6, while the average electron flux varies over three orders of magnitude from event to event. The spectral index of these cusp DEEs are(strongly) larger than the spectral index of solar wind superhalo electrons(radiation belt electrons) observed by the WIND 3 D Plasma & Energetic Particle instrument(the BD-IES). At^110 keV,the electron flux of DEEs in the cusp/polar cap/lobe shows a weak positive correlation with the solar wind superhalo electron flux but no obvious correlation with the radiation belt electron flux. These results suggest that these DEEs probably originate from transient processes acting on the solar wind superhalo electrons, e.g., the mid/high-latitude reconnection. | WANG LingHua ZONG QiuGang SHI QuanQi WANG YongFu TU ChuanYi HE JianSen TIAN Hui WIMMER-SCHWEINGRUBER Robert F. ZOU Hong | 2017 | Science China(Technological Sciences)2017，60，12： | 4 |
| 6 | Multi-satellite observations on the storm-time enhancements of energetic outer zone electron fluxes driven by chorus waves显示文摘The evolution of energetic outer zone electron fluxes during the strong magnetic storm on September 28, 2002 is investigated based on the observations of SAMPEX and GOES-10 satellites. The observations of both satellites showed that energetic electron fluxes increased significantly during the storm recovery phase, and reached the maximum on October 6. The 1.5–14 MeV and 2.5–14 MeV electron fluxes observed by SAMPEX peaked around L=3.5 with values of 6×10 2 cm -2 s -1 sr -1 keV -1 and 5×10 3 cm -2 s -1 sr -1 keV -1 , which were about 10 and 8 times the pre-storm values. At the geostationary orbit, the >0.6 MeV and >2 MeV electron fluxes observed by GOES-10 showed enhancement up to 50 and 30 times. The plasma parameters and whistler-mode chorus waves in the outer radiation belt are also analyzed based on the data from Cluster C3 satellite. Cluster C3 satellite went through the outer radiation belt twice from 1 October to 4 October, and observed whistler-mode chorus waves with high intensity (10 -5 –10 -4 nT 2 Hz -1 ). Numerical calculations indicated that the observed chorus waves were in gyro-resonance with the radiation belt electrons. The current observations and calculations provide new evidence for that the gyro-resonance with chorus waves contribute significantly to the buildup of energetic outer zone electron fluxes during storms. | HE ZhaoGuo XIAO FuLiang ZONG QiuGang WANG YongFu CHEN LiangXu YUE Chao ZHANG Sai | 2011 | Science China(Technological Sciences)2011，54，8： | 3 |
| 7 | Understanding High Saving Rate in China显示文摘这份报纸基于资金数据的流动论述中国节省率的详细分析。它发现预防节省的最广泛地采用的看法,它被认为是顶为在中国维持高节省率推理,因为这个结论从家庭调查数据被得出,是似是而非的。事实上,自从 mid-1990s,节省率的家庭戏剧性地衰退了,从资金框架的流动被观察。高国家的节省率被归因于管理和公司的增加的份额可处理的收入。不够的消费需求被坚持的减少在家庭的百分比份额引起到国家可处理的收入。管理 -- 指导收入再分配着急地需要被改善加速消费,它将接着使中国经济更少带投资并且帮助减少当前的帐户剩余。 | Xinhua He Yongfu Cao | 2007 | China & World Economy2007，15，1： | 3 |
| 8 | Balancing selection and wild gene pool contribute to resistance in global rice germplasm against planthopper显示文摘Interactions and co-evolution between plants and herbivorous insects are critically important in agriculture.Brown planthopper(BPH)is the most severe insect of rice,and the biotypes adapt to feed on different rice genotypes.Here,we present genomics analyses on 1,520 global rice germplasms for resistance to three BPH biotypes.Genome-wide association studies identified 3,502 single nucleotide polymorphisms(SNPs)and 59 loci associated with BPH resistance in rice.We cloned a previously unidentified gene Bph37 that confers resistance to BPH.The associated loci showed high nucleotide diversity.Genome-wide scans for trans-species polymorphisms revealed ancient balancing selection at the loci.The secondarily evolved insect biotypes II and III exhibited significantly higher virulence and overcame more rice varieties than the primary biotype I.In response,more SNPs and loci evolved in rice for resistance to biotypes II and III.Notably,three exceptional large regions with high SNP density and resistance-associated loci on chromosomes 4 and 6 appear distinct between the resistant and susceptible rice varieties.Surprisingly,these regions in resistant rice might have been retained from wild species Oryza nivara.Our findings expand the understanding of long-term interactions between rice and BPH and provide resistance genes and germplasm resources for breeding durable BPH-resistant rice varieties. | Cong Zhou Qian Zhang Yu Chen Jin Huang Qin Guo Yi Li Wensheng Wang Yongfu Qiu Wei Guan Jing Zhang Jianping Guo Shaojie Shi Di Wu Xiaohong Zheng Lingyun Nie Jiaoyan Tan Chaomei Huang Yinhua Ma Fang Yang Xiqin Fu Bo Du Lili Zhu Rongzhi Chen Zhikang Li Longping Yuan Guangcun He | 2021 | Journal of Integrative Plant Biology2021，63，10： | 2 |
| 9 | Empirical Testing of the Reference-Price Effect of Buy-Now Prices in Internet Auctions显示文摘 | Peter T.L. Popkowski Leszczyc Chun Qiu Yongfu He | 2009 | Journal of Retailing2009，，2： | 1 |
| 10 | Determination of absolute gamma-ray emission probabilities for ^(88)Kr显示文摘In preparation of homogeneous Kr and Rb sources,the Kr activity was determined by the decay relationship between ^(88)Kr and ^(88)Rb using an HPGe detector.The peak efficiencies of ^(88)Kr and ^(88)Rbγ-rays were calibrated.The results show that the absolute probabilities of 196.3,834.8,1529.8,2195.8 and 2392.1 keVγ-rays of ^(88)Kr were 25.1(5)%,12.9(2)%,10.7(2)%,13.3(2)%and 34.9(5)%,respectively. | XIE Feng HE Xiaobing JIANG Wengang CHEN Zhanying SHI Quanlin CHANG Yongfu | 2011 | Nuclear Science and Techniques2011，22，5： | 1 |
| 11 | Expression of Clock genes in the pineal glands of newborn rats with hypoxic-ischemic encephalopathy显示文摘Clock genes are involved in circadian rhythm regulation, and surviving newborns with hypoxic-ischemic encephalopathy may present with sleep-wake cycle reversal. This study aimed to determine the expression of the clock genes Clock and Bmal1, in the pineal gland of rats with hypoxic-ischemic brain damage. Results showed that levels of Clock mRNA were not significantly changed within 48 hours after cerebral hypoxia and ischemia. Expression levels of CLOCK and BMAL1 protein were significantly higher after 48 hours. The levels of Bmal1 mRNA reached a peak at 36 hours, but were significantly reduced at 48 hours. Experimental findings indicate that Clock and Bmal1 genes were indeed expressed in the pineal glands of neonatal rats. At the initial stage (within 36 hours) of hypoxic-ischemic brain damage, only slight changes in the expression levels of these two genes were detected, followed by significant changes at 36-48 hours. These changes may be associated with circadian rhythm disorder induced by hypoxic-ischemic brain damage. | Bin Sun Xing Feng Xin Ding Li Bao Yongfu Li Jun He Meifang Jin | 2012 | Neural Regeneration Research2012，7，28： | 1 |
| 12 | High-rate CH_(4)-to-C_(2)H_(6) photoconversion enabled by Au/ZnO porous nanosheets under oxygen-free system显示文摘Photocatalytic CH_(4) coupling into high-valued C_(2)H_(6) is highly attractive,whereas the photosynthetic rate,especially under oxygen-free system,is still unsatisfying.Here,we designed the negatively charged metal supported on metal oxide nanosheets to activate the inert C-H bond in CH_(4)and hence accelerate CH_(4) coupling performance.As an example,the synthetic Au/ZnO porous nanosheets exhibit the C_(2)H_(6) photosynthetic rate of 1,121.6μmol g^(-1)_(cat)h^(-1)and the CH_(4) conversion rate of 2,374.6μmol g^(-1)_(cat)h^(-1) under oxygen-free system,2 orders of magnitude higher than those of previously reported photocatalysts.By virtue of several in situ spectroscopic techniques,it is established that the generated Au^(δ-)and O^-species together polarized the C-H bond,while the Au^(δ-)and O^-species jointly stabilized the CH_(3) intermediates,which favored the coupling of CH_(3) intermediate to photosynthesize C_(2)H_(6) instead of overoxidation into CO_(x).Thus,the design of dual active species is beneficial for achieving high-efficient CH_(4)-to-C_(2)H_(6) photoconversion. | Kai Zheng Xiaojing Zhang Jun Hu Chengbin Xu Juncheng Zhu Jing Li Mingyu Wu Shan Zhu Li Li Shumin Wang Yumei Lv Xin He Ming Zuo Chengyuan Liu Yang Pan Junfa Zhu Yongfu Sun Yi Xie | 2024 | Science China Chemistry2024，67，3： | 0 |
| 13 | Epidemiological and clinical features,treatment status,and economic burden of traumatic spinal cord injury in China:a hospital-based retrospective study显示文摘Traumatic spinal cord injury is potentially catastrophic and can lead to permanent disability or even death.China has the largest population of patients with traumatic spinal cord injury.Previous studies of traumatic spinal cord injury in China have mostly been regional in scope;national-level studies have been rare.To the best of our knowledge,no national-level study of treatment status and economic burden has been performed.This retrospective study aimed to examine the epidemiological and clinical features,treatment status,and economic burden of traumatic spinal cord injury in China at the national level.We included 13,465 traumatic spinal cord injury patients who were injured between January 2013 and December 2018 and treated in 30 hospitals in 11 provinces/municipalities representing all geographical divisions of China.Patient epidemiological and clinical features,treatment status,and total and daily costs were recorded.Trends in the percentage of traumatic spinal cord injuries among all hospitalized patients and among patients hospitalized in the orthopedic department and cost of care were assessed by annual percentage change using the Joinpoint Regression Program.The percentage of traumatic spinal cord injuries among all hospitalized patients and among patients hospitalized in the orthopedic department did not significantly change overall(annual percentage change,-0.5%and 2.1%,respectively).A total of 10,053(74.7%)patients underwent surgery.Only 2.8%of patients who underwent surgery did so within 24 hours of injury.A total of 2005(14.9%)patients were treated with high-dose(≥500 mg)methylprednisolone sodium succinate/methylprednisolone(MPSS/MP);615(4.6%)received it within 8 hours.The total cost for acute traumatic spinal cord injury decreased over the study period(-4.7%),while daily cost did not significantly change(1.0%increase).Our findings indicate that public health initiatives should aim at improving hospitals’ability to complete early surgery within 24 hours,which is associated with improved sensorimotor recovery,increasing the awareness rate of clinical guidelines related to high-dose MPSS/MP to reduce the use of the treatment with insufficient evidence. | Hengxing Zhou Yongfu Lou Lingxiao Chen Yi Kang Lu Liu Zhiwei Cai David BAnderson Wei Wang Chi Zhang Jinghua Wang Guangzhi Ning Yanzheng Gao Baorong He Wenyuan Ding Yisheng Wang Wei Mei Yueming Song Yue Zhou Maosheng Xia Huan Wang Jie Zhao Guoyong Yin Tao Zhang Feng Jing Rusen Zhu Bin Meng Li Duan Zhongmin Zhang Desheng Wu Zhengdong Cai Lin Huang Zhanhai Yin Kainan Li Shibao Lu Shiqing Feng | 2024 | Neural Regeneration Research2024，19，5： | 0 |
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