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| 1 | Pulse-width-induced polarization enhancement of optically pumped N-V electron spin in diamond显示文摘The nitrogen-vacancy(N-V)center in diamond is a widely used platform for quantum information processing and sensing.The electron-spin state of the N-V center could be initialized,read out optically,and manipulated by resonate microwave fields.In this work,we analyze the dependence of electron-spin initialization on widths of laser pulses.We build a numerical model to simulate this process and to verify the simulation results in experiments.Both simulations and experiments reveal that shorter laser pulses are helpful to the electron-spin polarization.We therefore propose to use extremely short laser pulses for electron-spin initialization.In this new scheme,the spin-state contrast could be improved about 10%in experiments by using laser pulses as short as 4 ns in width.Furthermore,we provide a mechanism to explain this effect,which is due to the occupation time in the meta-stable spin-singlet states of the N-V center.Our new scheme is applicable in a broad range of N-V-based applications in the future. | YUMENG SONG YU TIAN ZHIYI HU FEIFEI ZHOU TENGTENG XING DAWEI LU BING CHEN YA WANG NANYANG XU JIANGFENG DU | 2020 | Photonics Research2020，8，8： | 1 |
| 2 | Anti-DLBCL efficacy of DCZ0825 in vitro and in vivo:involvement of the PI3K‒AKT‒mTOR/JNK pathway显示文摘Diffuse large B-cell lymphoma(DLBCL)is the most common type of non-Hodgkin lymphoma,characterized by high heterogeneity.The poor outcome of a portion of patients who suffer relapsing or resistant to conventional treatment impels the development of novel agents for DLBCL.DCZ0825 is a novel compound derived from pterostilbene and osalmide,whose antitumor activities have drawn our attention.In this study,we found that DCZ0825 exhibited high cytotoxicity toward DLBCL cell lines in a dose-and time-dependent manner,as revealed by cell counting kit-8 assay.Flow cytometry and western blot analysis results showed that DCZ0825 also promoted cell apoptosis via both extrinsic and intrinsic apoptosis pathways mediated by caspase.In addition,DCZ0825 induced cell cycle arrest in the G2/M phase by downregulating Cdc25C,CDK1,and Cyclin B1,thus interfering with cell proliferation.Further investigation showed the involvement of the phosphatidylinositol 3-kinase(PI3K)‒AKT‒mTOR/JNK pathway in the efficacy of DCZ0825 against DLBCL.Remarkably,DCZ0825 also exerted notable cytotoxic effects in vivo as well,with low toxicity to important internal organs such as the liver and kidney.Our results suggest that DCZ0825 may have the potential to become a novel anti-DLBCL agent or to replenish the conventional therapeutic scheme of DLBCL. | Ke Hu Bo Li Ruye Ma Hongfei Yi Zhijian Xu Yu Peng Dandan Yu Huiqun Wu Taofang Cheng Yumeng Lu Yong Zhang Rong Wei Guang Yang Xiaosong Wu Weiliang Zhu Jumei Shi | 2021 | Acta Biochimica et Biophysica Sinica2021，53，5： | 1 |
| 3 | Human Plague Case Diagnosed in Ningxia Tracked to Animal Reservoirs—Inner Mongolia Autonomous Region,China,2021显示文摘Summary What is already known about this topic?There were a total of 4 and 3 human plague cases that occurred in the Inner Mongolia Autonomous Region in 2019 and 2020,respectively,with 1 and 2 deaths in 2019 and 2020 respectively,which indicated that plague still poses a significant threat to human health especially for farmers,shepherds,or residents living in native plague foci.What is added by this report?On August 14,2021,1 patient from the Otog Qi(County)in the Inner Mongolia sought treatment in Yinchuan City(the capital of Ningxia Hui Autonomous Region). | Jianwei Gao Yanhong Hu Cheng Ju Jingyuan Liu Yiting Wang Jiangtao Ma Xiaona Shen Fang Liu Jin Guo Xinxin Yu Wen Zhang Shuyi Wang Kun Li Zhongbing Zhang Biao Kan Wenrui Wang Xianbin Cong Mengguang Fan Wei Li Kuidong Shao Tao Zhang Jianyun Li Yumeng Wang | 2021 | China CDC weekly2021，3，52： | 1 |
| 4 | Shock wave standoff distance of near space hypersonic vehicles显示文摘The shock wave standoff distances of near space hypersonic vehicles,which execute missions mainly at the altitude of 25 km to55 km,are vital in aerothermodynamic analysis.The implicit finite volume schemes are derived from axisymmetric Navier-Stokes equations for chemical equilibrium flow,and programmed in FORTRAN.Taking a sphere cone for example,the effects of Mach numbers(from 22 to 36) on the shock wave standoff distance and the average density behind the shock are simulated at different altitudes from 25 km to 55 km.The numerical results illustrate that the turning point of the standoff distance is corresponding to that of the average density with the variation of Mach numbers.Based on the numerical results,we propose a formula for shock wave standoff distance,which is the function of the radius of the blunt body,the Mach number and the altitude in the atmosphere.Compared with previous correlations,the new formula can overcome the drawbacks of larger relative errors and complex calculations of the average density. | HU YuMeng HUANG HaiMing GUO Jin | 2017 | Science China(Technological Sciences)2017，60，8： | 1 |
| 5 | A Study on Tourist Interaction in Mountain-type Scenic Spots显示文摘Mountain tourism is one of the traditional and important forms of tourism in China. In mountain tourism,the interaction between tourists often occurs,and is paid attention to in tourism sociology. In the field of tourism research,it involves a large number of host-guest interaction studies in tourism destinations,but there is little research on the interaction between tourists. Therefore,in the study of mountaintype scenic spots,we can also study the tourist interaction from the perspective of tourist experience and symbolic interaction theory. | Zhuo LI Yumeng XIE Yingchun HU | 2018 | Asian Agricultural Research2018，10，5： | 0 |
| 6 | In-depth understanding of ionic liquid assisted perovskite film formation mechanism for two-step perovskite photovoltaics显示文摘Ionic liquids(ILs)have been widely applied in the one-step fabrication of perovskite with noticeable enhancement in the device performance.However,in-depth mechanism of ionic-liquid-assisted perovskite film formation is not well understood for also important two-step perovskite fabrication method,with better control of crystallization behavior.In this work,we introduced ionic liquid methylammonium formate(MAFa)into organic salt to produce perovskite film via a two-step method.Systematic investigations on the influence of MAFa on the perovskite thin film formation mechanism were performed.Ionic liquid is shown to assist lowering the perovskite formation enthalpy upon the density functional theory(DFT)calculation,leading to an accelerated crystallization process evidenced by in-situ UV-Vis absorption measurement.A gradient up-down distribution of ionic liquid has been confirmed by timeof-flight SIMS.Importantly,besides the surface passivation,we found the HCOO-can diffuse into the perovskite crystals to fill up the halide vacancies,resulting in significant reduction of trap states.Uniform perovskite films with significantly larger grains and less defect density were prepared with the help of MAFa IL,and the corresponding device efficiency over 23%was obtained by two-step process with remarkably improved stability.This research work provides an efficient strategy to tune the morphology and opto-electronic properties of perovskite materials via ionic-liquid-assisted two-step fabrication method,which is beneficial for upscaling and application of perovskite photovoltaics. | Fei Wang Patrick Wai-Keung Fong Zhiwei Ren Hai-Lun Xia Kang Zhou Kai Wang Jiajie Zhu Xiaoxi Huang Xiao-Yuan Liu Hao Wang Yumeng Shi Haoran Lin Quanyao Zhu Gang Li Hanlin Hu | 2022 | Journal of Energy Chemistry2022，31，10： | 0 |
| 7 | Achieving Tunable Cold/Warm White‑Light Emission in a Single Perovskite Material with Near‑Unity Photoluminescence Quantum Yield显示文摘Single materials that exhibit efficient and stable white-light emission are highly desirable for lighting applications.This paper reports a novel zero-dimensional perovskite,Rb_(4)CdCl_(6):Sn^(2+),Mn^(2+),which demonstrates exceptional white-light properties including adjustable correlated color temperature,high color rendering index of up to 85,and near-unity photoluminescence quantum yield of 99%.Using a co-doping strategy involving Sn^(2+)and Mn^(2+),cyan-orange dual-band emission with complementary spectral ranges is activated by the self-trapped excitons and d-d transitions of the Sn^(2+)and Mn^(2+)centers in the Rb_(4)CdCl_(6)host,respectively.Intriguingly,although Mn^(2+)ions doped in Rb_(4)CdCl_(6)are difficult to excite,efficient Mn^(2+)emission can be realized through an ultra-high-efficient energy transfer between Sn^(2+)and Mn^(2+)via the formation of adjacent exchange-coupled Sn–Mn pairs.Benefiting from this efficient Dexter energy transfer process,the dual emission shares the same optimal excitation wavelengths of the Sn^(2+)centers and suppresses the non-radiative vibration relaxation significantly.Moreover,the relative intensities of the dual-emission components can be modulated flexibly by adjusting the fraction of the Sn^(2+)ions to the Sn–Mn pairs.This co-doping approach involving short-range energy transfer represents a promising avenue for achieving high-quality white light within a single material. | Bo Zhou Aixuan Du Dong Ding Zexiang Liu Ye Wang Haizhe Zhong Henan Li Hanlin Hu Yumeng Shi | 2023 | Nano-Micro Letters2023，15，11： | 0 |
| 8 | Performance Analysis of an Organic Rankine Cycle with a Preheated Ejector显示文摘The so-called organic Rankine cycle(ORC)is an effective technology allowing heat recovery from lower temperature sources.In the present study,to improve its thermal efficiency,a preheated ejector using exhaust steam coming from the expander is integrated in the cycle(EPORC).Considering net power output,pump power,and thermal efficiency,the proposed system is compared with the basic ORC.The influence of the ejector ratio(ER)of the preheated ejector on the system performances is also investigated.Results show that the net power output of the EPORC is higher than that of the basic ORC due to the decreasing pump power.Under given working conditions,the average thermal efficiency of EPORC is 29%higher than that of ORC.The ER has a great impact on the performance of EPORC by adjusting the working fluid fed to the pump,leading to significant variations of the pump work Moreover,the ER has a remarkable effect on the working fluid temperature lift(TL)at the evaporator inlet,thus reducing the evaporator heat load.According to the results,the thermal efficiency of EPORC increases by 30%,when the ER increases from 0.05 to 0.4. | Kaiyong Hu Yumeng Zhang Tianrun Zhang Dequan Zhang Zhaoxian Yang | 2022 | Fluid Dynamics & Materials Processing2022，18，4： | 0 |
| 9 | Ionic liquid engineering enabled in-plane orientated 1D perovskite nanorods for efficient mixed-dimensional perovskite photovoltaics显示文摘Mixed-dimensional engineering of perovskite material has been demonstrated as a facile and promising strategy to improve both photovoltaic performance and long-term stability of perovskite solar cells(PSCs).In this study,we report an in-plane preferred orientation of 1D perovskite induced by an ionic liquid(IL)of 1-(3-cyanopropyl)-3-methylimidazolium chloride(CPMIMCl)for the first time via sequential deposition approach,leading to a mixed dimensional perovskite thin films.The generated one-dimensional(1D)CPMIMPbI3 with in-plane orientation resides at the grain boundaries of three-dimensional(3D)perovskite can be appreciably observed from the morphology level,leading to creation of high-quality films with large grain size with more efficient defect passivation.Moreover,the dispersion of IL in the bulk phase of perovskite material allows for the formation of 1D perovskite for multiple level passivation to inhibit non-radiative recombination and optimize carrier transport.This IL engineering strategy not only yields a mixed-dimensional perovskite heterostructure with in-plane orientation 1D perovskite nano-rods but also significantly improves the opto-electronic property with suppressed trap states.As a result,the CPMIMCl-treated PSCs show an enhanced photovoltaic performance with a champion power conversion efficiency(PCE)up to 24.13%.More importantly,benefiting from the hydrophobicity of formed 1D perovskite and defects suppression,the corresponding PSC demonstrates an excellent longterm stability and maintain 97.1%of its pristine PCE at 25C under 50%RH condition over 1000 h.This research provides an innovative perspective for employing the low dimensional engineering to optimize the performance and stability of photovoltaic devices. | Fei Wang Dawei Duan Kang Zhou YZBXue Xiao Liang Xianfang Zhou Chuangye Ge Chao Zhou Jin Xiang Jiajie Zhu Quanyao Zhu Haoran Lin Yumeng Shi Yonghua Chen Gang Li Hanlin Hu | 2023 | InfoMat2023，5，8： | 0 |
| 10 | E3 ligase MG53 suppresses tumor growth by degrading cyclin D1显示文摘Due to the essential role of cyclin D1 in regulating transition from G1 to S phase in cell cycle,aberrant cyclin D1 expression is a major oncogenic event in many types of cancers.In particular,the dysregulation of ubiquitination-dependent degradation of cyclin D1 contributes to not only the pathogenesis of malignancies but also the refractory to cancer treatment regiments with CDK4/6 inhibitors.Here we show that in colorectal and gastric cancer patients,MG53 is downregulated in more than 80%of tumors compared to the normal gastrointestinal tissues from the same patient,and the reduced MG53 expression is correlated with increased cyclin D1 abundance and inferior survival.Mechanistically,MG53 catalyzes the K48-linked ubiquitination and subsequent degradation of cyclin D1.Thus,increased expression of MG53 leads to cell cycle arrest at G1,and thereby markedly suppresses cancer cell proliferation in vitro as well as tumor growth in mice with xenograft tumors or AOM/DSS induced-colorectal cancer.Consistently,MG53 deficiency results in accumulation of cyclin D1 protein and accelerates cancer cell growth both in culture and in animal models.These findings define MG53 as a tumor suppressor via facilitating cyclin D1 degradation,highlighting the therapeutic potential of targeting MG53 in treating cancers with dysregulated cyclin D1 turnover. | Meng Fang Hong-Kun Wu Yumeng Pei Yan Zhang Xiangyu Gao Yanyun He Gengjia Chen Fengxiang Lv Peng Jiang Yumei Li Wenwen Li Peng Jiang Lin Wang Jiafu Ji Xinli Hu Rui-Ping Xiao | 2023 | Signal Transduction and Targeted Therapy2023，8，8： | 0 |
| 11 | Controlled growth of ultrathin ferromagneticβ-MnSe semiconductor显示文摘Two-dimensional(2D)magnetic crystals with intrinsic ferromagnetism are highly desirable for novel spin-electronic devices.However,the controllable synthesis of 2D magnets,especially the direct growth of 2D magnets on substrate surfaces,is still a challenge.Here,we demonstrate the synthesis of ultrathin zinc-blende phase manganese selenide(β-MnSe)nanosheets using the chemical vapor deposition(CVD)technique.The 2Dβ-MnSe crystals exhibit distinct ferromagnetic properties with a Curie temperature of 42.3 K.Density functional theory(DFT)calculations suggest that the ferromagnetic order inβ-MnSe originates from the exchange coupling between the unsaturated Se and Mn atoms.This study presents significant progress in the CVD growth of ultrathin 2D magnetic materials by thinning bulk magnets,and it will pave the way for the building of energy-efficient spintronic devices in the future. | Jingyun Zou Yumeng Yang Dianyi Hu Lixing Kang Chao Zhu Dan Tian Xiaodong Lv Govindan Kutty Yuxi Guo Manzhang Xu Fengyu Li Guo Hong Zheng Liu | 2022 | SmartMat2022，3，3： | 0 |
| 12 | Dihydrocelastrol induces antitumor activity and enhances the sensitivity of bortezomib in resistant multiple myeloma by inhibiting STAT3-dependent PSMB5 regulation显示文摘Multiple myeloma(MM)is characterized by excessive aggregation of B-cell-derived malignant plasma cells in the hematopoietic system of bone marrow.Previously,we synthesized an innovative molecule named dihydrocelastrol(DHCE)from celastrol,a triterpene purified from medicinal plant Tripterygium wilfordii.Herein,we explore the therapeutic properties and latent signal transduction mechanism of DHCE action in bortezomib(BTZ)-resistant(BTZ-R)MM cells.In this study,we first report that DHCE shows antitumor activities in vitro and in vivo and exerts stronger inhibitory effects than celastrol on BTZ-R cells.We find that DHCE inhibits BTZ-R cell viability by promoting apoptosis via extrinsic and intrinsic pathways and suppresses BTZ-R MM cell proliferation by inducing G0/G1 phase cell cycle arrest.In addition,inactivation of JAK2/STAT3 and PI3K/Akt pathways are involved in the DHCE-mediated antitumor effect.Simultaneously,DHCE acts synergistically with BTZ on BTZ-R cells.PSMB5,a molecular target of BTZ,is overexpressed in BTZ-R MM cells compared with BTZ-S MM cells and is demonstrated to be a target of STAT3.Moreover,DHCE downregulates PSMB5 overexpression in BTZ-R MM cells,which illustrates that DHCE overcomes BTZ resistance through increasing the sensitivity of BTZ in resistant MM via inhibiting STAT3-dependent PSMB5 regulation.Overall,our findings imply that DHCE may become a potential therapeutic option that warrants clinical evaluation for BTZ-R MM. | Shuhan Jin Bo Li Bibo Zhang Xuejie Gao Xinyan Jia Li Xu Shuaikang Chang Ke Hu Guanli Wang Zhijian Xu Ting Zhang Dongliang Song Guang Yang Xiaosong Wu Huabin Zhu Cheng Huang Yumeng Lu Jumei Shi Weiliang Zhu Gege Chen | 2023 | Acta Biochimica et Biophysica Sinica2023，55，12： | 0 |
| 13 | Efficient energy transfer in organic light-emitting transistor with tunable wavelength显示文摘Key challenges in the development of organic light-emitting transistors(OLETs)are blocking both scientific research and practical applications of these devices,e.g.,the absence of high-mobility emissive organic semiconductor materials,low device efficiency,and color tunability.Here,we report a novel device configuration called the energy transfer organic light-emitting transistor(ET-OLET)that is intended to overcome these challenges.An organic fluorescent dye-doped polymethyl methacrylate(PMMA)layer is inserted below the conventional high-mobility organic semiconductor layer in a single-component OLET to separate the functions of the charge transport and light-emitting layers,thus making the challenge to essentially integrate the high mobility and emissive functions within a single organic semiconductor in a conventional OLET or multilayer OLET unnecessary.In this architecture,there is little change in mobility,but the external quantum efficiency(EQE)of the ET-OLET is more than six times that of the conventional OLET because of the efficient Förster resonance energy transfer,which avoids exciton-charge annihilation.In addition,the emission color can be tuned from blue to white to green-yellow using the sourcedrain and gate voltages.The proposed structure is promising for use with electrically pumped organic lasers. | Ke Zhou Jian Tang Shaofan Fang Ke Jiang Fangxu Yang Deyang Ji Jing Xiang Jie Liu Huanli Dong(✉) Cheng Han Hanlin Hu Xiaotao Zhang Wenping Hu Yumeng Shi | 2022 | Nano Research2022，15，4： | 0 |
| 14 | TransQuake: A transformer-based deep learning approach for seismic P-wave detection显示文摘Recent years,we have witnessed the increasing research interest in developing machine learning,especially deep learning which provides approaches for enhancing the performance of microearthquake detection.While considerable research efforts have been made in this direction,most of the state-of-the-art solutions are based on Convolutional Neural Network(CNN)structure,due to its remarkable capability of modeling local and static features.Indeed,the globally dynamic characteristics contained within time series data(i.e.,seismic waves),which cannot be fully captured by CNN-based models,have been largely ignored in previous studies.In this paper,we propose a novel deep learning approach,TransQuake,for seismic P-wave detection.The approach is based on the most advanced sequential model,namely Transformer.To be specific,TransQuake can exploit the STA/LTA algorithm for adapting the three-component structure of seismic waves as input,and take advantage of the multi-head attention mechanism for conducting explainable model learning.Extensive evaluations of the aftershocks following the 2008 Wenchuan MW 7.9 earthquake clearly demonstrates that TransQuake is able to achieve the best detection performance which excels the results obtained using other baselines.Meanwhile,experimental results also validate the interpretability of the results obtained by TransQuake,such as the attention distribution of seismic waves in different positions,and the analysis of the optimal relationship between coda wave and P-wave for noise identification. | Yumeng Hu Qi Zhang Wenjia Zhao Haitao Wang | 2021 | Earthquake Research Advances2021，1，2： | 0 |
| 15 | Synthesis and electromagnetic transport of large-area 2D WTe_(2) thin film显示文摘Tungsten telluride thin films were successfully prepared on monocrystal sapphire substrates by using atomic layer de-position and chemical vapor deposition technology,and the effects of different tellurization temperatures on the properties of tungsten telluride films were investigated.The growth rate,crystal structure and composition of the film samples were character-ized and analyzed by using scanning electron microscope,Raman spectroscopy and X-ray photoelectron spectroscopy.The res-ults showed that tungsten telluride thin films with good crystal orientation in(001)were obtained at telluride temperature of 550℃.When the telluride temperature reached 570℃,the tungsten telluride began to decompose and unsaturated mag-netoresistance was found. | Yumeng Zhang Zhejia Wang Jiaheng Feng Shuaiqiang Ming Furong Qu Yang Xia Meng He Zhimin Hu Jing Wang | 2022 | Journal of Semiconductors2022，43，10： | 0 |
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