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| 1 | Effect of electroacupuncture on chemotherapy-induced peripheral neuropathy in patients with malignant tumor:a single-blinded,randomized controlled trial显示文摘OBJECTIVE:To evaluate the effect of electroacupuncture on chemotherapy-induced peripheral neuropathy(CIPN), quality of life and immune status of patients with malignant tumors.METHODS:From Jan, 2013 to May, 2014, 37 patients with malignant tumors were included in this prospective single-blinded study, and randomized to receive either electroacupuncture or acupuncture treatment on basis of chemotherapy.The chemotherapy was continued for 2 courses as previous before the treatments, with 21 days as a course of treatment.Patients received acupuncture and electroacupuncture once per day starting at the day before chemotherapy for consecutive 7 days followed by 14 days off, with 21 days as a course of treatment, and continued for two courses of treatment.Then CIPN, traditional Chinese clinical symptoms,quality of life and immune status were all evaluated for each patient prior treatment and after two courses of treatment.RESULTS:The gender, age, cancer species as well as incidence(83.3% vs 84.2%) and grades of CIPN before treatments were all similar in patients receiving acupuncture or electroacupuncture(all P >0.05).After treatments, most patients with peripheral neuropathy were cured by two courses of electroacupuncture(84.2% vs 21.1%), whereas the other group of patients had similar incidences of peripheral neuropathy compared with prior-acupuncture(83.3% vs 72.2%).Besides, patients receiving electroacupuncture had lower incidence of peripheral neuropathy than those receiving acupuncture treatment(χ~2= 9.745, P = 0.002).The grades of peripheral neuropathy were significantly different in the two groups post-treatment(χ~2= 13.983, P =0.007).The total effective rates for traditional Chinese clinical symptoms were 16.7% and 84.2% in acupuncture and electroacupuncture groups, respectively(Z =-4.239, P < 0.001).The electroacupuncture treatment provided a more satisfactory life for patients compared with acupuncture(Z =-4.76, P < 0.001).Both electroacupuncture and acupuncture had no effects on immune function.CONCLUSION:Electroacupuncture could alleviate CIPN, and improve traditional Chinese clinical symptoms and quality of life, but did not affect immune function. | Zhang Shiqiang Wu Tingting Zhang Haisheng Yang Yun Jiang Haiyan Cao Shengcheng Xie Fang Xia Xiaoting Lü Junqiang Zhong Yi | 2017 | Journal of Traditional Chinese Medicine2017，37，2： | 7 |
| 2 | Solidification microstructure selection of the peritectic Nd-Fe-B alloys显示文摘Bridgman directional solidification and laser remelting experiments were carried out on Nd11.76Fe82.36B5.88 and Nd13.5Fe79.75B6.75 alloys.Microstructure evolutions along with solidification parameters(temperature gradient G,growth velocity V and initial alloy composition C0)were investigated.A solidification microstructure selection map was established,based on the consideration of solidification characteristics of peritectic T1 phase.In Bridgman directional solidification experiments,with the increasing growth velocities,the morphology of T1 phase changed from plane front or faceted plane front to dendrites.In laser remelting experiments,a transition from primary γ-Fe dendrites to T1 dendrites was found.Theoretical predictions are in good agreement with experimental results. | ZHONG Hong LI ShuangMing LüHaiYan LIU Lin ZOU GuangRong FU HengZhi | 2007 | Science China(Physics,Mechanics & Astronomy)2007，50，4： | 4 |
| 3 | Herbal formula of Bushen Jianpi(补肾健脾方)combined with sorafenib inhibits hepatocellular carcinoma growth by promoting cell apoptosis and blocking the cell cycle显示文摘OBJECTIVE:To investigate the efficacy of an herbal formula of Bushen Jianpi(补肾健脾方,BSJP)combined with sorafenib on hepatocellular carcinoma(HCC)in vitro and in vivo,and to study the underlying mechanisms of action.METHODS:BSJP,a mixture of 12 raw herbs,was extracted in 70%alcohol/30%water and freeze-dried into a powder.The in vitro effects of BSJP alone,sorafenib alone,and their combination on cell survival,apoptosis,and cell cycle distribution were evaluated in HCC cell lines HCCLM3,HepG2,and SMMC-7721.The expression of B-cell lymphoma-2(Bcl-2),caspase-3,and caspase-9 in HCCLM3 cells was measured using Western blots after drug administration.The in vivo effects of BSJP and sorafenib were evaluated in a tumor surgical resection model using 4-week old male athymic BALB/c nude mice injected with HCCLM3 cells.Immunohistochemical analysis of tumor tissues was performed to evaluate the effects of BSJP alone,sorafenib alone,and their combination on the expression of caspase-3,caspase-9,and Bcl-2.RESULTS:BSJP decreased the survival rate of HCC cell lines,and the combination of BSJP and sorafenib further decreased the survival rate.BSJP significantly promoted cell apoptosis and blocked cell-cycle progression in HCCLM3,HepG2,and SMMC-7721 cells in a dose-dependent manner.Furthermore,the administration of BSJP and sorafenib inhibited the growth of HCCLM3 cell xenografts in nude mice,with no reduction in body weight.In vivo and in vitro experiments showed that BSJP combined with sorafenib could significantly decrease the expression of Bcl-2.CONCLUSION:Our findings suggest that the herbal formula of BSJP is a potential HCC antitumor agent. | ZHOU Zhangjie LIU Xinhua WU Tingting QUE Zujue WU Zhonghua WU Weizhong FU Shujuan ZHANG Shiqiang YANG Yun JIANG Haiyan XIA Xiaoting LV Junqiang DU Boqian LI Yun LU Tao ZHANG Zhihui ZHONG Yi | 2021 | Journal of Traditional Chinese Medicine2021，41，2： | 3 |
| 4 | Effects of intercropping with persimmon on the rhizosphere environment of tea显示文摘The rhizosphere environment of tea(Camelllia sinensis Kuntze)intercropped with persimmon(Diospyros kaki)differs from monocultures of tea.A trial was conducted to determine the effects of intercropping with persimmon on root exudates and soil nutrient condition of tea.Amino acid exuded in intercropping was three times higher than that in monoculture.Phenol,phenol/amino acid ration,dissolved sugar,and total organic acid were also lower in intercropping.The value of pH in soil was higher,and soil nutrient condition of rhizosphere,especially available nutrient,was not as well in intercropping as that in tea grown alone.While soil nutrient of non-rhizosphere was better than that in monoculture,tea quality and soil nutrient condition were better in intercropping ecosystem. | ZHU Haiyan LIU Zhongde WANG Changrong ZHONG Zhangcheng | 2006 | Frontiers in Biology2006，1，4： | 2 |
| 5 | Linearization of Multi-Valued Nonlinear Feedback Shift Registers显示文摘Nonlinear feedback shift registers(NFSRs) have been used in many stream ciphers for cryptographic security. The linearization of NFSRs is to describe their state transitions using some matrices. Such matrices are called their state transition matrices. Compared to extensive work on binary NFSRs, much less work has been done on multi-valued NFSRs. This paper uses a semi-tensor product approach to investigate the linearization of multi-valued NFSRs, by viewing them as logical networks. A new state transition matrix is found for a multi-valued NFSR, which can be simply computed from the truth table of its feedback function. The new state transition matrix is easier to compute and is more explicit than the existing results. Some properties of the state transition matrix are provided as well, which are helpful to theoretically analyze multi-valued NFSRs. | WANG Haiyan ZHONG Jianghua LIN Dongdai | 2017 | Journal of Systems Science & Complexity2017，30，2： | 2 |
| 6 | Effects of a combination of Japanese Raisin Tree Seed and Flower of Lobed Kudzuvine against acute alcohol-induced liver injury in mice显示文摘Objective:The Flower of Lobed Kudzuvine[Pueraria lobata(Willd.)Ohwi;Gehua in Chinese;GH]and Japanese Raisin Tree Seed(Hovenia dulcis Thunnb.;Zhijuzi in Chinese;ZJZ)are herbs that have been used in China for the treatment of alcohol intoxication and liver diseases.We aimed to evaluate the hepatoprotective potential of a combination of these in mice with acute alcohol-induced liver injury,and to elucidate the mechanisms involved.Methods:Male ICR mice were randomly allocated to six groups:a control group,an alcohol-administered group,and groups that were administered alcohol and one of silibinin,the GH,the ZJZ or a GH-ZJZ combination(at a ratio of 2:1).Animals were orally administered 56%alcohol(Er Guo-tou white spirit,0.12 mL/10 g/d)for 10 days and at the end of this period,hepatic biochemical indicators,antioxidant parameters,alcohol metabolic enzymes,and histopathologic changes were evaluated.Moreover,the expression of the signaling molecules KEAP1,NRF2,and AQP9 were measured by qRT-PCR and western blotting.Results:Compared with the model group,GH-ZJZ(2:1)had lower serum ALT(12.15±0.39,P紏.003),AST(104.07±1.03,P紏.001),and ALP(148.09±2.55,P紏.010)activities,and lower TC(1.97±0.05,P紏.001)and TG(1.54±0.07,P?.002)concentrations.GH-ZJZ(2:1)also significantly increased the hepatic activities of SOD and GSH(4.24±0.25 and 1.57±0.06,respectively;both P<.01),reduced the ROS and MDA concentrations(97.50±3.00 and 2.39±0.19,respectively;both P<.01),and upregulated Nrf2 expression(P<.01).GH-ZJZ(2:1)significantly reduced the expression of KEAP1 and AQP9 in the liver,compared with alcohol-administered mice(P<.01).Importantly,the GH-ZJZ combination caused a more marked improvement in acute liver injury than GH or ZJZ alone.Conclusion:We have demonstrated protective effects of GH-ZJZ(2:1)against acute alcohol-induced hepatic injury,and shown that these effects may be associated with improvements in lipid and alcohol metabolism,antioxidant capacity,and lipid peroxidation. | Wan Xu Shaohong Chen Gansheng Zhong Haiyan Liu Linlin Xiu Xue Yu Feng Chen Na Li Yanmin Lv | 2020 | Journal of Traditional Chinese Medical Sciences2020，7，1： | 2 |
| 7 | Cocoon Silk-Derived, Hierarchically Porous Carbon as Anode for Highly Robust Potassium-Ion Hybrid Capacitors显示文摘Potassium-ion hybrid capacitors(KIHCs) have attracted increasing research interest because of the virtues of potassium-ion batteries and supercapacitors.The development of KIHCs is subject to the investigation of applicable K+storage materials which are able to accommodate the relatively large size and high activity of potassium.Here,we report a cocoon silk chemistry strategy to synthesize a hierarchically porous nitrogen-doped carbon(SHPNC).The as-prepared SHPNC with high surface area and rich N-doping not only offers highly efficient channels for the fast transport of electrons and K ions during cycling,but also provides sufficient void space to relieve volume expansion of electrode and improves its stability.Therefore,KIHCs with SHPNC anode and activated carbon cathode afford high energy of 135 Wh kg-1(calculated based on the total mass of anode and cathode),long lifespan,and ultrafast charge/slow discharge performance.This study defines that the KIHCs show great application prospect in the field of high-performance energy storage devices. | Haiyan Luo Maoxin Chen Jinhui Cao Meng Zhang Shan Tan Lei Wang Jiang Zhong Hongli Deng Jian Zhu Bingan Lu | 2020 | Nano-Micro Letters2020，12，9： | 2 |
| 8 | The PSCA polymorphisms derived from genome-wide association study are associated with risk of gastric cancer: a meta-analysis显示文摘 | Danni Shi Shizhi Wang Dongying Gu Dongmei Wu Meilin Wang Haiyan Chu Na Tong Lan Ma Dongyan Zhong Zhengdong Zhang | 2012 | Journal of Cancer Research and Clinical Oncology2012，，8： | 2 |
| 9 | Semi-chemical interaction between graphitic carbon nitride and Pt for boosting photocatalytic hydrogen evolution显示文摘Owing to the exorbitant overpotential and serious carrier recombination of graphitic carbon nitride(gC_(3)N_(4)),noble metal(NM)is usually served as the H_(2)evolution co-catalyst.Although the NM(such as Pt)nanoparticles can reduce the H_(2)evolution overpotential,the weak van der Waals interaction between Pt and g-C_(3)N_(4)makes against the charge transfer.Herein,the solvothermal method is developed to achieve semi-chemical interaction between Pt and g-C_(3)N_(4)nanotube(Pt-CNNT)for fast charge transfer.Moreover,the generated in-plane homojunction of CNNT can accelerate charge separation and restrain recombination.Meanwhile,the metallic Pt is an excellent H_(2)evolution co-catalyst.Photo/electrochemical tests verify that the semi-chemical interaction can improve photogenerated charge separation and transferability of CNNT.As a result,the photocatalytic H_(2)evolution turnover frequency(TOF)of Pt-CNNT under visible light irradiation reaches up to 918 h^(-1),which is one of the highest in the g-C_(3)N_(4)-based photocatalysts.This work provides a new idea to improve the charge transfer for efficient photocatalytic H_(2)evolution. | Ziai Zhong Lisha Chen Longshuai Zhang Feiyao Wu Xunheng Jiang Haiyan Liu Fengrong Lv Haiyang Xie Fanqi Meng Lingling Zheng Jianping Zou | 2022 | Chinese Chemical Letters2022，33，6： | 1 |
| 10 | Endogenous biophe- nol, fatty acid and volatile profiles of selected oils 显示文摘 | Zhong Haiyan Danny R Bedgood J | 2007 | Food Chemistry2007，100，4： | 1 |
| 11 | Endogenous biophenol, fatty acid and volatile profiles of selected oils显示文摘 | Zhong Haiyan Danny R Bedgood J r | 2007 | Food Chemislry2007，，100： | 1 |
| 12 | Unraveling the role of Ti3C2 MXene underlayer for enhanced photoelectrochemical water oxidation of hematite photoanodes显示文摘Hematite is regarded as a promising photoanode for photoelectrochemical(PEC) water splitting.However,the charge recombination occurred at the interface of FTO/hematite strictly limits the PEC performance of hematite.Herein,we reported a Ti3C2 MXene underlayer modified hematite(Ti-Fe2O3) photoanode via a simple drop-casting followed by hydrothermal and annealing processes.Owing to the bifunctional role of Ti3C2 MXene underlayer in improving the interfacial properties of FTO/hematite and providing Ti source for the construction of Fe2 TiO5/Fe2O3 heterostructure in hematite nanostructure,the bulk and interfacial charge transfer dynamics of hematite are significantly enhanced,and consequently enhancing the PEC performance.Compared with the pristine hematite,the as-prepared Ti-Fe2O3 photoanode shows an increased photocurrent density from 0.80 mA/cm^(2) to 1.30 mA/cm^(2) at 1.23 V vs.RHE.Moreover,a further promoted PEC performance including a dramatically increased photocurrent density of 2.49 mA/cm^(2) at1.23 V vs.RHE and an obviously lowered onset potential is achieved for the Ti-Fe2O3 sample after the subsequent surface F-treatment and the loading of FeNiOOH cocatalyst.Such results suggest that the introduction of Ti3C2 MXene underlayer is a facile but effective approach to improve the PEC water splitting activity of hematite. | Haiyan Ji Shan Shao Guotao Yuan Cheng Lu Kun Feng Yujian Xia Xiaoxin Lv Jun Zhong Hui Xu Jiujun Deng | 2021 | Journal of Energy Chemistry2021，30，1： | 1 |
| 13 | Endogenous biophenol, fatty acid and volatile profiles of selected oils显示文摘 | Zhong Haiyan Bedgood D Bishop A | | Food Chemistry0，100，4： | 1 |
| 14 | Adsorption of surfactants on a Pseudomonas aeruginosa strain and the effect on cell surface lypohydrophilic property显示文摘 | XingZhong Yuan FangYi Ren GuangMing Zeng Hua Zhong HaiYan Fu Jia Liu XinMiao Xu | 2007 | Applied Microbiology and Biotechnology2007，，5： | 1 |
| 15 | Co-degradation with glucose of four surfactants, CTAB, Triton X-100, SDS and Rhamnolipid, in liquid culture media and compost matrix显示文摘 | Guangming Zeng Haiyan Fu Hua Zhong Xingzhong Yuan Muxing Fu Wei Wang Guohe Huang | 2007 | Biodegradation2007，，3： | 1 |
| 16 | Clinical application of massively parallel sequencing‐based prenatal noninvasive fetal trisomy test for trisomies 21 and 18 in 11 105 pregnancies with mixed risk factors显示文摘 | Shan Dan Wei Wang Jinghui Ren Yali Li Hua Hu Zhengfeng Xu Tze Kin Lau Jianhong Xie Weihua Zhao Hefeng Huang Jiansheng Xie Luming Sun Xiaohong Zhang Weipeng Wang Shixiu Liao Rong Qiang Jiangxia Cao Qiufang Zhang Yulin Zhou Haiyan Zhu Mei Zhong Yi Guo Linhu | 2012 | Prenat Diagn2012，，13： | 1 |
| 17 | Endogenous biophenol, fatty acid and volatile profiles of selected oils 显示文摘 | Zhong Haiyan Danny R Bedgood | 2007 | Food Chemistry2007，100，4： | 1 |
| 18 | Endogenous biophenol,fatty acid and volatile profiles of selected oils显示文摘 | Zhong Haiyan Danny R Bedgood J | | 0，，4： | 1 |
| 19 | Development of quantitative analysis of fatty acid for monitoring changes of fatty acid profile of camellia oil 显示文摘 | ZHU Yong ZHONG Haiyan SUN Hanzhou | 2012 | Advanced Materials Research2012，，： | 1 |
| 20 | Quality two-way feedback mode in PIH cesarean section parturients nursing application value显示文摘 | Xiong Haiyan Zhong Min Wei Qun Huang | 2013 | Hebei Medical2013，19，10： | 1 |
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