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| 1 | Essential oil and aromatic plants as feed additives in non-ruminant nutrition:a review显示文摘This paper summarizes the current knowledge regarding the possible modes of action and nutritional factors involved in the use of essential oils(EOs) for swine and poultry.EOs have recently attracted increased interest as feed additives to be fed to swine and poultry,possibly replacing the use of antibiotic growth promoters which have been prohibited in the European Union since 2006.In general,EOs enhance the production of digestive secretions and nutrient absorption,reduce pathogenic stress in the gut,exert antioxidant properties and reinforce the animal's immune status,which help to explain the enhanced performance observed in swine and poultry.However,the mechanisms involved in causing this growth promotion are far from being elucidated,since data on the complex gut ecosystem,gut function,in vivo oxidative status and immune system are still lacking.In addition,limited information is available regarding the interaction between EOs and feed ingredients or other feed additives(especially pro- or prebiotics and organic acids).This knowledge may help feed formulators to better utilize EOs when they formulate diets for poultry and swine. | Zhikai Zeng Sai Zhang Hongliang Wang Xiangshu Piao | 2016 | Journal of Animal Science and Biotechnology2016，7，1： | 19 |
| 2 | Complement C3 activation regulates the production of tRNA-derived fragments Gly-tRFs and promotes alcohol-induced liver injury and steatosis显示文摘Complement is known to play a role in alcoholic fatty liver disease (AFLD), but the underlying mechanisms are poorly understood, thereby constraining the development of a rational approach for therapeutic intervention in the complement system. C3 deficiency has been shown to impart protective effects against ethanol-induced hepatic steatosis and inflammation. Here we demonstrate a protection effect in wild-type mice by treatment with CR2-Crry, a specific inhibitor of C3 activation. The expression of glycine transfer (t) RNA-derived fragments (Gly-tRFs) is upregulated in ethanol-fed mice and inhibition of Gly-tRFs in vivo decreases chronic ethanol feeding-induced hepatosteatosis without affecting inflammation. The expression of Gly-tRF was downregulated in C3-deficient or CR2-Crry-treated mice, but not in C5-deficient mice;Gly-tRF expression was restored by the C3 activation products C3a or Asp (C3a-des-Arg) via the regulation of CYP2E1. Transcriptome profiling of hepatic tissues showed that Gly-tRF inhibitors upregulate the expression of sirtuin1 (Sirt1) and subsequently affect downstream lipogenesis and β-oxidation pathways. Mechanistically, Gly-tRF interacts with AGO3 to downregulate Sirt1 expression via sequence complementarity in the 3′ UTR. Notably, the expression levels of C3d, CYP2E1 and Gly-tRF are upregulated, whereas Sirt1 is decreased in AFLD patients compared to healthy controls. Collectively, our findings suggest that C3 activation products contribute to hepatosteatosis by regulating the expression of Gly-tRF. Complement inhibition at the C3 activation step and treatment with Gly-tRF inhibitors may be potential and precise therapeutic approaches for AFLD. | Fudi Zhong Zhigao Hu Keqing Jiang Biao Lei Zhan Wu Guandou Yuan Hongliang Luo Chunqiang Dong Bo Tang Chaowen Zheng Shuai Yang Yonglian Zeng Zhenya Guo Shuiping Yu Huizhao Su Guo Zhang Xiaoqiang Qiu Stephen Tomlinson Songqing He | 2019 | Cell Research2019，29，7： | 14 |
| 3 | Serum IgA,IgM,and IgG responses in COVID-19显示文摘Currently,detecting SARS-CoV-2 RNAs is a standard approach for COVID-19 diagnosis.However,there is an urgent need for reliable and rapid serological diagnostic methods to screen SARS-CoV-2-infected people including those who do not have overt symptoms.Most emerging studies described serological tests based on detection of SARS-CoV-2-specific IgM and IgG.1–4 Although detection of SARS-CoV-2-specific IgA in serum has been reported in few papers,5,6 analyses of IgA levels in a larger number of COVID-19 patients are still lacking. | Huan Ma Weihong Zeng Hongliang He Dan Zhao Dehua Jiang Peigen Zhou Linzhao Cheng Yajuan Li Xiaoling Ma Tengchuan Jin | 2020 | Cellular & Molecular Immunology2020，17，7： | 12 |
| 4 | Manipulation of Band Degeneracy and Lattice Strain for Extraordinary PbTe Thermoelectrics显示文摘Maximizing band degeneracy and minimizing phonon relaxation time are proven to be successful for advancing thermoelectrics.Alloying with monotellurides has been known to be an effective approach for converging the valence bands of PbTe for electronic improvements,while the lattice thermal conductivity of the materials remains available room for being further reduced.It is recently revealed that the broadening of phonon dispersion measures the strength of phonon scattering,and lattice dislocations are particularly effective sources for such broadening through lattice strain fluctuations.In this work,a fine control of MnTe and EuTe alloying enables a significant increase in density of electron states near the valence band edge of PbTe due to involvement of multiple transporting bands,while the creation of dense in-grain dislocations leads to an effective broadening in phonon dispersion for reduced phonon lifetime due to the large strain fluctuations of dislocations as confirmed by synchrotron X-ray diffraction.The synergy of both electronic and thermal improvements successfully leads the average thermoelectric figure of merit to be higher than that ever reported for p-type PbTe at working temperatures. | Yixuan Wu Pengfei Nan Zhiwei Chen Zezhu Zeng Siqi Lin Xinyue Zhang Hongliang Dong Zhiqiang Chen Hongkai Gu Wen Li Yue Chen Binghui Ge Yanzhong Pei | 2020 | Research2020，，1： | 6 |
| 5 | Abiogenic hydrocarbons in commercial gases from the Songliao Basin,China显示文摘This paper discusses the kinetic fractionation, composition and distribution characteristics of carbon and hydrogen isotopes for various alkane gases formed in different environments, by different mecha- nisms and from different sources in nature. It is demonstrated that the biodegradation or thermode- gradation of complex high-molecule sedimentary organic material can form microbial gas or thermogenic gas. The δ 13C1 value ranges from -110‰ to -50‰ for microbial gases but from -50‰ to -35‰ (even heavier) for thermogenic gases. Controlled by the kinetic isotope fractionation, both microbial and thermogenic gases have δ 13C and δ D values characterized by normal distribution, i.e. δ 13C1< δ 13C2< δ 13C3< δ 13C4 and δ DCH4< δ DC2H6< δ DC3H8<δ DC4H10, and by a positive correlation between the δ 13C and δ D values. Simple carbonbearing molecules (CH4, CO and CO2) can form abiogenic alkane gases via polymerization in the abiological chemical process in nature, with δ 13C1 heavier than -30‰. Moreover, controlled by the kinetic isotope fractionation, abiogenic alkane gases are characterized by a reverse distribution of δ 13C values and a normal trend of δ D values, namely δ 13C1> δ 13C2> δ 13C3> δ 13C4 and δ DCH4<δ DC2H6< δ DC3H8< δ DC4H10. The δ 13C values and δ D values are negatively correlated. Natural gases from 26 commercial gas wells distributed in the Xujiaweizi and Yingshan-Miaotaizi faulted depressions in the Songliao Basin, China, show δ13C1 values ranging from -30.5‰ to -16.7‰ with a very narrow δ D range between -203‰―-196‰. These gases are characterized by a reverse distribution of δ 13C values but a normal distribution of δ D values, and a negative correlation between their δ 13C and δ D values, indicating an abiological origin. The present study has revealed that abiogenic hydrocarbons not only exist in nature but also can make significant contribution to commercial gas reserviors. It is estimated that the reserve volume of alkane gases with abiogenic characteristics in these 26 gas wells in the Songliao Basin is over 500×108 m3. The prospecting practice in the Songliao Basin has demonstrated that abiogenic alkane gases are of a promising resource, and it provides an example for the investigation of and search for abiogenic commercial natural gases worldwide. | WANG XianBin GUO ZhanQian TUO JinCai GUO HongYan LI ZhenXi ZHUO ShengGuang JIANG HongLiang ZENG LongWei ZHANG MingJie WANG LianSheng LIU ChunXue YAN Hong LI LiWu ZHOU XiaoFeng WANG YongLi YANG Hui WANG Guang | 2009 | Science China Earth Sciences2009，52，2： | 6 |
| 6 | Inhibition of inflammatory mediator release from microglia can treat ischemic/hypoxic brain injury显示文摘Interleukin-1α and interleukin-1β aggravate neuronal injury by mediating the inflammatory reaction following ischemic/hypoxic brain injury. It remains unclear whether interleukin-1α and interleukin-1β are released by microglia or astrocytes. This study prepared hippocampal slices that were subsequently subjected to oxygen and glucose deprivation. Hematoxylin-eosin staining verified that neurons exhibited hypoxic changes. Results of enzyme-linked immunosorbent assay found that interleukin-1α and interleukin-1β participated in this hypoxic process. Moreover, when hypoxic injury occurred in the hippocampus, the release of interleukin-1α and interleukin-1β was mediated by the P2X4 receptor and P2X7 receptor. Immunofluorescence staining revealed that during ischemia/hypoxia, the P2X4 receptor, P2X7 receptor, interleukin-1α and interleukin-1β expression was detectable in rat hippocampal microglia, but only P2X4 receptor and P2X7 receptor expression was detected in astrocytes. Results suggested that the P2X4 receptor and P2X7 receptor, respectively, mediated interleukin-1α and interleukin-1β released by microglia, resulting in hippocampal ischemic/hypoxic injury. Astrocytes were activated, but did not synthesize or release interleukin-1α and interleukin-1β. | Huaibo Wang Weitao Guo Hongliang Liu Rong Zeng Mingnan Lu Ziqiu Chen Qixian Xiao | 2013 | Neural Regeneration Research2013，8，13： | 5 |
| 7 | High prevalence of pathogenic Leptospira in wild and domesticated animals in an endemic area of China显示文摘Objective:To assess the prevalence of Leptospira detected in wildlife and domesticated animals in Jiangxi Province,China,in 2009.Methods:Urine samples from 28 buffaloes and kidney samples from 50 pigs,50 dogs and 38 rats were collected from Fuliang and Shangrao County,Jiangxi Province,China,in October 2009.Polymerase chain reaction(PCR) and culture analyses were used to detect Leptospira.The cultured isolates were typed using the microscopic agglutination lest(MAT).Results:The results showed that rats potentially serve as the main reservoir of leptospiral infection,followed by dogs.Although 16%of rats(6/38) were positive using culture analysis,PCR analysis using the diagnostic primers G1/G2 and B64Ⅰ/B64Ⅱor lipLS2 showed identification as 50%and 24%,respectively,of the rat samples as positive for the presence of leptospiral DNA.Conclusions:PCR-based detection of leptospiral DNA in infected kidney tissues of reservoirs is more efficient when using G1/G2 primers than lipL32 primers. However,the latter primers have a potential application for detection in urine samples.The alarmingly high prevalence of leptospiral DMA in the wild rat population near human habitation underscores the utility of routine Leptospira surveillance,preferably using PCR methods,which are more sensitive than traditional culture-based methods. | Wang Yalin Zeng Lingbing Yang Hongliang Xu Jianmin Zhang Xiangyan Guo Xiaokui Pal Utpal Qin Jinhong | 2011 | Asian Pacific Journal of Tropical Medicine2011，4，11： | 2 |
| 8 | Structure elucidation and in vitro rat intestinal fermentation properties of a novel sulfated glucogalactan from Porphyra haitanensis显示文摘This study was to investigate the structure and rat fecal microbial fermentation properties of a polysaccharide fraction(PHP2)isolated from the red marine alga Porphyra haitanensis.PHP2 was characterized as a sulfated glucogalactan,with a hypothetical backbone structure of→4)Gα(1→6)G4 Sβ(1→4)Glc(1→and a side chain of Man(1→6)Glc.PHP2 had an irregular spherical chain conformation.The 16 S r RNA sequence analysis revealed that PHP2 modulated the rat fecal micro-flora composition,with a similar effect to inulin,changing the dominant genus(Lactobacillus and Escherichia-Shigella)and promoting the growth of organisms that degrade sulfur-containing polysaccharides,such as Desulfovibrio,Ruminococcaceae_UCG-005,and Ruminococcus_2.PHP2 can promote production of acetic,propionic and butyric acid by rat fecal micro-flora.Prediction of metabolic function suggested that PHP2 could modulate cholesterol metabolism.The sulfated glucogalactan fermentation behavior may be associated with its monosaccharide composition,chain branching and chain conformation.PHP2 appeared to have considerable potential as functional food,and was associated with sulfur-containing polysaccharides in general. | Peilin Chen Lu Liu Zirun Cheng Yi Zhang Baodong Zheng Xiaoke Hu Hongliang Zeng | 2023 | Food Science and Human Wellness2023，12，2： | 2 |
| 9 | Fine mapping a QTL qCTB7 for cold tolerance at the booting stage on rice chromosome 7 using a near-isogenic line显示文摘 | Lei Zhou Yawen Zeng Weiwei Zheng Bo Tang Shuming Yang Hongliang Zhang Jinjie Li Zichao Li | 2010 | Theoretical and Applied Genetics2010，，5： | 2 |
| 10 | The role of the IRE1 pathway in PBDE-47-induced toxicity in human neuroblastoma SH-SY5Y cells in vitro显示文摘 | Chunyang Jiang Shun Zhang Hongliang Liu Qiang Zeng Tao Xia Yihu Chen Gang Kuang Guodong Zhao Xue Wu Xiaofei Zhang Aiguo Wang | 2012 | Toxicology Letters2012，，3： | 1 |
| 11 | A new π-conjugated star-shaped polymer comprising of full fluorene units: An efficient blue emitter without reduction of color purity undergoing an annealing显示文摘 | Shijie Ren Jiangong Cheng Danli Zeng Wenqing Zhu Jing Sun Junping Du Erjian Xu Hongliang Zhong Yingchun Liu Qiang Fang | 2008 | Synthetic Metals2008，，1： | 1 |
| 12 | Saliency detection using joint spatial-color constraint and multi-scale segmentation显示文摘 | Xu Linfeng Li Hongliang Zeng Liaoyuan | 2013 | Journal of Visual Communication and Image Representation2013，24，4： | 1 |
| 13 | Study on activated carbon derived from sewage sludge for adsorption of gaseous formaldehyde显示文摘 | Qingbo Wen Caiting Li Zhihong Cai Wei Zhang Hongliang Gao Lijun Chen Guangming Zeng Xin Shu Yapei Zhao | 2010 | Bioresource Technology2010，，2： | 1 |
| 14 | Experim- ental study of wet flue gas desulphurization with a novel type PCF device显示文摘 | Gao Hongliang Li Caiting Zeng Guangming | 2011 | Chemical Engineering and Processing2011，50，2： | 1 |
| 15 | Temporal-spatial Analysis on Urban and Rural Drinking Water Health Monitoring of Tianjin in 2013显示文摘[Objective] Grasp quality and health status of drinking water,and provide scientific basis for decision making of health administrative department. [Method]According to the Standards for Drinking Water Quality( GB 5749- 2006),monitoring results of Tianjin urban and rural drinking water health in 2013 were evaluated,and software SPSS 20. 0 and GeoD a was used for temporal-spatial analysis on water quality. [Result]There were 2 882 copies of monitoring samples in total,in which both finished water and tap water of urban district were qualified,while qualified rates of tap water and secondary water supply from the county were respectively 86. 36% and 93. 91%,and major exceeding indexes were pH and total number of colonies. Qualified rates of tap water and secondary water supply from the county had difference( χ2= 1 576. 875,P < 0. 01). Quality of tap water( χ2= 5. 425,P > 0. 05) and secondary water supply( χ2= 16. 009,P > 0. 05) was stable at temporal distribution( January-December),but spatial distribution of tap water had certain regional difference( χ2= 1 255. 802,P < 0. 01). [Conclusion] General quality situation of Tianjin urban and rural drinking water was better,but qualified rate of water quality in some counties was lower,which had safety risk and threatened the health of residents in the corresponding county. The related departments should enhance the supervision and management of drinking water supply,improve supply water quality,strengthen water quality monitoring,and guarantee drinking water safety. Geographic information system can better realize visualization of drinking water quality monitoring information. | Fu Gang Zeng Qiang Zhao Liang Feng Baojia Wang Rui Zhang Lei Wang Yang Cui Yushan Zhang Yue Liu Hongliang | 2016 | Meteorological and Environmental Research2016，7，3： | 1 |
| 16 | Responses of rice and winter wheat to free-air CO2 enrichment (China FACE) at rice/wheat rotation system显示文摘 | Hongliang Ma Jianguo Zhu Zubin Xie Gang Liu Qing Zeng Yong Han | 2007 | Plant and Soil (-)2007，，1： | 1 |
| 17 | Ultrasonic- assisted extraction and antioxidant activity of polysaccharides recovered from white button mushroom ( Agaricus bisporus) 显示文摘 | Tian Yuting Zeng Hongliang Xu Zhenbo | 2012 | Carbohydrate Polymers2012，88，2： | 1 |
| 18 | Saliency detection using joint spatial-color constraint and multi-scale segmentation显示文摘 | Xu Linfeng Li Hongliang Zeng Liaoyuan | 2013 | Journal of Visual Communication and Image Representation2013，24，4： | 1 |
| 19 | Saliency Detection Using Joint Spatial-color Constraint and Multi-scale Segmentation显示文摘 | Xu Lingfeng Li Hongliang Zeng Liaoyuan | 2013 | Journal of Visual Communication and Image Representation2013，24，4： | 1 |
| 20 | Ultrasonic-assisted extraction and antioxidant activity of polysaccharides recovered from white button mushroom (Agaricus bisporus)显示文摘 | TIAN Yuting ZENG Hongliang XU Zhenbo | 2012 | Carbohydrate Polymers2012，88，2： | 1 |
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