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| 1 | Lane departure warning systems and lane line detection methods based on image processing and semantic segmentation:A review显示文摘Recently,the development and application of lane line departure warning systems have been in the market.For any of the systems,the key part of lane line tracking,lane line identification,or lane line departure warning is whether it can accurately and quickly detect lane lines.Since 1990 s,they have been studied and implemented for the situations defined by the good viewing conditions and the clear lane markings on road.After then,the accuracy for particular situations,the robustness for a wide range of scenarios,time efficiency and integration into higher-order tasks define visual lane line detection and tracking as a continuing research subject.At present,these kinds of lane marking line detection methods based on machine vision and image processing can be divided into two categories:the traditional image processing and semantic segmentation(includes deep learning)methods.The former mainly involves feature-based and model-based steps,and which can be classified into similarity-and discontinuity-based ones;and the model-based step includes different parametric straight line,curve or pattern models.The semantic segmentation includes different machine learning,neural network and deep learning methods,which is the new trend for the research and application of lane line departure warning systems.This paper describes and analyzes the lane line departure warning systems,image processing algorithms and semantic segmentation methods for lane line detection. | Weiwei Chen Weixing Wang Kevin Wang Zhaoying Li Huan Li Sheng Liu | 2020 | Journal of Traffic and Transportation Engineering(English Edition)2020，7，6： | 14 |
| 2 | Inflammasome activation in mouse inner ear in response to MCMV induced hearing loss显示文摘Objective: To identify presence of inflammasome activated in mouse cochlea with sensorineural hearing loss(SNHL) caused by cytomegalovirus(CMV) infection.Method: MCMV was injected into the right cerebral hemisphere in neonatal BALB/c mice at 2000 pfu virus titers. Auditory brainstem responses(ABRs) were tested to evaluate hearing at 21 days. Histopathological studies were conducted to confirm localizations of MCMV infected cells in the inner ear. Expression of inflammasome related factors was assessed by immunofluorescence, Quantitative real-time PCR and Western blotting.Results: In the mouse model of CMV induced SNHL, inflammasome related kinase Caspase-1 and downstream inflammatory factor IL-1b and IL-18 were found increased and activated after CMV infection in the cochlea. These factors could further up-regulate expression of IL-6 and TNFa. These inflammatory factors are neurotoxicity and may contribute to hearing impairment. Furthermore, we also detected significantly increased AIM2 protein that accumulated in the SGN of cochleae with CMV infection.Significance: We have shown that inflammasome as a novel inherent immunity mechanism may contribute to hearing impairment.Conclusion: Our data indicate that imflammasome assemble in mouse inner ear in response to CMV infection. We have revealed a novel pathology event in CMV induced SNHL involving activation of inflammasome in mouse cochlea. Additionally, we have shown that inflammasome may be a novel target for prevention and treatment of CMV related SNHL. | Xi Shi Yanfen Dong Ya Li ZenLu Zhao Huan Li Shiwei Qiu Yaohan Li Weiwei Guo Yuehua Qiao | 2015 | Journal of Otology2015，10，4： | 9 |
| 3 | Structural insights into Cas13b-guided CRISPR RNA maturation and recognition显示文摘Dear Editor,CRISPR-Cas (clustered regularly interspaced short palindromic repeats and CRISPR-associated proteins)systems are RNA-guided adaptive immune systems in prokaryotes.^1,2 Class 2 CRISPR-Cas systems (including type Ⅱ,Ⅴ,and Ⅵ)involve large single effector proteins in complex with crRNA for interference. | Bo Zhang Weiwei Ye Yangmiao Ye Huan Zhou Abdullah F.U.H.Saeed Jing Chen Jinying Lin Vanja Perculija Qi Chen Chun-Jung Chen Ming-Xian Chang Muhammad lqbal Choudhary Songying Ouyang | 2018 | Cell Research2018，28，12： | 5 |
| 4 | Strategies to improve electrochemical performances of pristine metal‐organic frameworks‐based electrodes for lithium/sodium‐ion batteries显示文摘Metal‐organic frameworks(MOFs)have attracted considerable attention as promising next‐generation active electrode materials for lithium‐ion batteries(LIBs)or sodium‐ion batteries(SIBs)because of ultrahigh specific surface area,uniformly distributed pores,and tunable structure.However,there are some disadvantages inevitably far from meeting commercial requirements,such as low conductivity,inconvenient electron transmission,and unsatisfactory circulation stability.In this review,a comprehensive summary of MOFs‐based electrode materials is presented and discussed.First,the general Li^(^(+))/Na^(+)storage mechanism in MOFs‐based electrode materials,including conversion‐and insertion‐type reactions,are summarized with details of active inorganic/organic ligands.Second,MOFs as anode materials for LIBs/SIBs are emphasized and improved on the electrochemical performances.Furthermore,very few research literature on MOFs‐based cathode materials is also discussed.Finally,opinions and prospects on the current challenge of MOFs‐based electrode materials are provided for future research directions. | Zhoujia Liu Fenfen Zheng Weiwei Xiong Xiaogang Li Aihua Yuan Huan Pang | 2021 | SmartMat2021，2，4： | 3 |
| 5 | Anaerobic biodegradation,physical and structural properties of normal and high-amylose maize starch films显示文摘Biodegradable plastics have attracted considerable attention in recent years due to their biodegradability,biocompatibility and non-toxicity.In this study,normal maize starch(containing 25%amylose)and high-amylose maize starch(containing 80%amylose)were served as model materials to prepare starch/polyvinyl alcohol(PVA)blends.To comprehensively study the effects of amylose contents on the film performances,the mechanical properties,water resistance and anaerobic biodegradability of the two films were examined.Moreover,the processes of anaerobic degradation were investigated by evolutions of biogas production,pH in reactors and the changes of film structures and compositions.The results indicated that amylose content played an important role in the microstructures of starch film as well as mechanical properties and water resistance,whereas it had no significant influence on anaerobic biodegradability of the films.Nonetheless,the structure of high-amylose maize starch/PVA film was more suitable and beneficial to the anaerobic biodegradation than that of the normal maize starch/PVA film,because it could effectively avoid accumulation of volatile fatty acids,which contributed to the stable biogas production,short fermentation period and non-souring in the reactor. | Liu Weiwei Xue Juan Cheng Beijiu Zhu Suwen Ma Qing Ma Huan | 2016 | International Journal of Agricultural and Biological Engineering2016，9，5： | 3 |
| 6 | The preventive effect of vaccine prophylaxis on severe respiratory syncytial virus infection:A meta-analysis显示文摘Respiratory syncytial virus(RSV) is the key underlying cause of acute lower respiratory tract infection in infants; however, no licensed vaccine against RSV infection is currently available. This study was undertaken to assess the preventive effect of vaccine on RSV infection. In this metaanalysis, 1,792 published randomized clinical trials of RSV vaccines from Jan 1973 to Sep 2015 were examined. Among thirteen studies that met the inclusion criteria, eleven studies estimated the impact of RSV vaccines and four studies estimated the effect of adjuvants. The odds ratios(ORs) were 0.31(95% CI, 0.15–0.67) and 0.62(95% CI, 0.29–1.34), respectively. We found that RSV subunit vaccines can significantly reduce the incidence of RSV infection and that whether vaccination with adjuvant therapy was an effective strategy still remained to be studied. This analysis of the preventive effect of vaccines on RSV infection has direct applications for the prevention of RSV infections. | Tongna Zhu Chuanlong Zhang Li Yu Jingxian Chen Huan Qiu Weiwei Lyu Shenghai Huang | 2015 | Virologica Sinica2015，30，5： | 2 |
| 7 | Transcriptional profile in response to ionizing radiation at low dose in Deinococcus radiodurans显示文摘Deinococcus radiodurans 房间的染色体宽的抄写侧面与低剂量照耀在处理以后被调查, 2 kGy ) 。从表示侧面,我们发现 DNA 修理的过程被导致有序,即涉及基础切除修理,核苷酸切除修理并且单个海滨的退火的基因在电离以后立即被导致包括消遣 A,为再结合修理的放射,和基因收到, recQ 然后被激活。特别收到, recQ 明确地在低剂量照耀被导致,并且这现象通知我们这二基因将在反氧化起某个作用。象 ddrA 和 ssb 那样的一些基因在整个修理阶段期间被激活。而且,在低剂量照耀下面的氧化压力相关的基因的反应显示出一个不同模式从尖锐高级照耀,许多抗氧化的基因被导致清除反应的氧种类直接,另外的联系系统也在恢复时间期间改变了他们的表达式模式例如铁新陈代谢系统,细胞内部的诱变的先锋清洁系统。这些特征显示在 Deinococcus radiodurans 有一个强大、有序的恢复过程。 | Chen Huan Xu Zhenjian Tian Bing Chen Weiwei Hu Songnian Hua Yuejin | 2007 | Progress in Natural Science:Materials International2007，17，5： | 2 |
| 8 | Degradation of 2,4-DCP by the Immobilized Laccase on the Carrier of Fe304@SiO2-NH2显示文摘在这份报纸,在 Fe3O4@SiO2-NH2 nanoparticles 上使不能调动的 laccase 被 glutaraldehyde cross-linking 方法成功地准备。laccase 催化并且使 laccase 不能调动的 2,4-dichlorophenol (2,4-DCP ) 的降级被执行。关于降级效率的最佳的条件也被讨论,它包括反应时间, pH 价值,温度, 2,4-DCP 和 laccase 的集中。当 laccase 被 crosslinking 与 glutaraldehyde 在 Fe3O4@SiO2-NH2 搬运人上使不能调动时,稳定性和重复显著地被改进。由使不能调动的 laccase 的 2,4-DCP 的移动效率在操作的六个周期以后仍然是超过 59% 。 2,4-DCP 的降级是一阶的反应, laccase 催化并且使 laccase 不能调动的 2,4-DCP 的激活精力是 51.93 kJ 敶?湡?硥楨楢整?楨桧猠汥'虡N楶祴愠摮猠湥楳楴楶祴映牯???潩獮?獁愠???浡汰晩敩?汦潵敲'諟?牰扯??獴映畬牯獥散据?灳'虪箾溪e潨敷???潦摬攠桮湡散敭瑮椠?桴?湩整獮瑩?景琠敨猠杩慮?瑡??渠?湯戠湩楤杮眠瑩?桴?牃??慂敳?湯琠敨映畬牯獥散据?楴牴瑡潩?灳'虪?湡?潊??汰瑯愠慮祬楳?戠湩楤杮洠摯?景丠児?眠瑩?牃?眠獡瀠潲潰敳??畬牯獥散据?湩整獮瑩?慷?楬敮牡眠瑩?潣据湥牴瑡潩?景???慣楴湯椠?? | Huan Weiwei Yang Yuxiang Wu Bin Yuan Hongming Zhang Yani Liu Xiangnong | 2012 | Chinese Journal of Chemistry2012，30，12： | 2 |
| 9 | Systematic review of pentachlorophenol occurrence in the environment and in humans in China: Not a negligible health risk due to the re-emergence of schistosomiasis显示文摘 | Weiwei Zheng Huan Yu Xia Wang Weidong Qu | 2011 | Environment International2011，，： | 1 |
| 10 | Esterase-catalyzed dePEGylation of pH-sensitive vesicles modified with cleavable PEG-lipid derivatives显示文摘 | Huan Xu Yihui Deng Dawei Chen Weiwei Hong Yi Lu Xiaohui Dong | 2008 | Journal of Controlled Release2008，，3： | 1 |
| 11 | Enhanced enzy- matic saccharification of rico straw by microwave pretrcat- ment 显示文摘 | Ma Huan Liu Weiwei Chen Xing | 2009 | Bioresource Technology2009，100，3： | 1 |
| 12 | Multi-Feature Fusion-Guided Multiscale Bidirectional Attention Networks for Logistics Pallet Segmentation显示文摘In the smart logistics industry,unmanned forklifts that intelligently identify logistics pallets can improve work efficiency in warehousing and transportation and are better than traditional manual forklifts driven by humans.Therefore,they play a critical role in smart warehousing,and semantics segmentation is an effective method to realize the intelligent identification of logistics pallets.However,most current recognition algorithms are ineffective due to the diverse types of pallets,their complex shapes,frequent blockades in production environments,and changing lighting conditions.This paper proposes a novel multi-feature fusion-guided multiscale bidirectional attention(MFMBA)neural network for logistics pallet segmentation.To better predict the foreground category(the pallet)and the background category(the cargo)of a pallet image,our approach extracts three types of features(grayscale,texture,and Hue,Saturation,Value features)and fuses them.The multiscale architecture deals with the problem that the size and shape of the pallet may appear different in the image in the actual,complex environment,which usually makes feature extraction difficult.Our study proposes a multiscale architecture that can extract additional semantic features.Also,since a traditional attention mechanism only assigns attention rights from a single direction,we designed a bidirectional attention mechanism that assigns cross-attention weights to each feature from two directions,horizontally and vertically,significantly improving segmentation.Finally,comparative experimental results show that the precision of the proposed algorithm is 0.53%–8.77%better than that of other methods we compared. | Weiwei Cai Yaping Song Huan Duan Zhenwei Xia Zhanguo Wei | 2022 | Computer Modeling in Engineering & Sciences2022，，6： | 1 |
| 13 | The heterogeneity and dynamic equilibrium of rat embryonic stem cells显示文摘 | Yan Shen Cheng Shi Wei Wei Weidong Yu Wenlin Li Yang Yang Jun Xu Wenqin Ying Xin Sui Lingling Fang Weiwei Lin Huan Yang Sheng Ding Huan Shen Yan Shi Hongkui Deng | 2011 | Cell Research2011，21，7： | 1 |
| 14 | Enhanced enzymatic saccharification of rice straw by microwave pretreatment显示文摘 | Ma Huan Liu Weiwei Chen Xing Wu Yuejin Yu Zengliang | 2009 | Bioresource Technology2009，100，： | 1 |
| 15 | Single-dose AAV-based vaccine induces a high level of neutralizing antibodies against SARS-CoV-2 in rhesus macaques显示文摘Dear Editor,Coronavirus disease 2019(COVID-19)is a highly infectious respiratory disease that continues to pose a serious global public health emergency.The disease shows a high infection rate,long incubation period,and rapidly emerging variants,which have led to its rapid spread worldwide(Krammer 2020).Many vaccines have been developed for the control of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),the virus responsible for COVID-19,including vaccines based on messenger RNA(mRNA)(Polack et al.2020),viral vectors(Zhu et al.2020),recombinant proteins(Yang et al.2020),and inactivated SARS-CoV-2(Zhang et al.2021). | Dali Tong Mei Zhang Yunru Yang Han Xia Haiyang Tong Huajun Zhang Weihong Zeng Muziying Liu Yan Wu Huan Ma Xue Hu Weiyong Liu Yuan Cai Yanfeng Yao Yichuan Yao Kunpeng Liu Shifang Shan Yajuan Li Ge Gao Weiwei Guo Yun Peng Shaohong Chen Juhong Rao Jiaxuan Zhao Juan Min Qingjun Zhu Yanmin Zheng Lianxin Liu Chao Shan Kai Zhong Zilong Qiu Tengchuan Jin Sandra Chiu Zhiming Yuan Tian Xue | 2023 | Protein & Cell2023，14，1： | 0 |
| 16 | IgE Reactivity of Potential Allergens from the Swimming Crab Portunus trituberculatus and the Research of ELISA Reagent for Detecting Crab Food Anaphylaxis显示文摘Crustacean is one of the major allergic foods.It is of great significance to identify more crab allergens and research the detection methods for crab food anaphylaxis.In this study,IgE reactivity to three recombinant proteins from Portunus trituberculatus,including tropomyosin(rPtTM),myosin light chain(rPtMLC),and pancreatic lipase(rPtPL),were detected by enzyme-linked im-munosorbent assay(ELISA).The expressions of tropomyosin(TM)in various tissues of P.trituberculatus were detected by Western blot(WB).Furthermore,microplates were coated with rPtTM and the ELISA conditions were optimized.The cut-off value was deter-mined by the receiver operating characteristic(ROC)curve.Among 51 crab-allergic sera,21(41.2%)showed positive IgE to rPtTM.Other 70 crab-allergic sera more frequently recognized rPtPL(9/70;12.9%),followed by rPtMLC(1/70;1.4%).WB results showed that TM was mainly expressed in the muscle,followed by the heart and a small amount in gills and the testis.The optimal results showed that the coating condition of rPtTM was 50 ng per well with coating for 3 h at 37℃.The optimal blocking condition was 1.2%BSA with blocking for 3 h at 37℃,and the optimal dilution of the second antibody was 1:1500.The ROC curve showed that the ELISA reagent had high sensitivity(83.52%)and specificity(98.00%)when the cut-off value was 0.45.All results indicated that tropomyosin is the major allergen of P.trituberculatus,and myosin light chain and pancreatic lipase are the potential allergens.Addi-tionally,the ELISA reagent developed with the rPtTM was feasible for laboratory detection of crab anaphylaxis. | QIU Xueni ZHOU Qiongyan ZHU Xiaoxia LIN Wei MU Changkao LI Ronghua YE Yangfang SONG Weiwei SHI Ce LIU Lei WANG Huan WANG Chunlin XU Suling | 2022 | Journal of Ocean University of China2022，21，2： | 0 |
| 17 | Factors to consider in the verification of urinary biomarkers显示文摘Dear Editor,Because urine is not under homeostatic control, changes occur earlier in urine than in blood; therefore, urine is a better source of early and sensitive biomarkers. The composition of urine is affected by a variety of factors, and urine is susceptible to complex changes. To exclude the impact of multiple factors, an appropriate animal model can be used in which control over all experimental factors is possible and each factor can be separately observed. Additionally, some common confounding factors should be considered when choosing disease candidate biomarkers for clinical verification. | Yuhang Huan Weiwei Qin Youhe Gao | 2018 | Science China(Life Sciences)2018，61，10： | 0 |
| 18 | 高产酒精肺炎克雷伯菌引起的非酒精性脂肪肝病显示文摘文章简介非酒精性脂肪肝(NAFLD)具有进展为肝硬化和肝细胞癌的风险,其潜在病因多种多样,目前认为NAFLD与肠道微生物群的变化有关,然而,它们之间的因果关系尚不清楚。研究团队发现肠道菌群中高产酒精的肺炎克雷伯菌(HiAlc Kpn)可能是NAFLD的一个病因。在NAFLD患者人群中,高达60%的患者肠道菌群中含有HiAlc Kpn。 | 袁静 Chen Chen Jinghua Cui Jing Lu Chao Yan Xiao Wei Xiangna Zhao NanNan Li Shaoli Li Guanhua Xue Weiwei Cheng Boxing Li Huan Li Weishi Lin Changyu Tian Jiangtao Zhao Juqiang Han Daizhi An Qiong Zhang Hong Wei Minghua Zheng Xuejun Ma Wei Li Xiao Chen Zheng Zhang Hui Zeng Sun Ying JianXin Wu Ruifu Yang 刘翟 | 2020 | 科学新闻2020，，2： | 0 |
| 19 | LiCoO_(2) sintering aid towards cathode-interface-enhanced garnet electrolytes显示文摘Garnet-type Li_7La_(3)Zr_(2)O_(12)(LLZO) has high ionic conductivity and good compatibility with lithium metal.High-temperature processing has been proven an effective method to decrease the interface resistance of cathodeILLZO.However,its application is still hindered by the interlayer co-diffusion with the cathode and high sintering temperature(>1200℃).In this work,a new garnet-type composite solid-state electrolyte(SSE) Li_(6.54)La_(2.96)Ba_(0.04)Zr_(1.5)Nb_(0.5)O_(12)-LiCoO_(2)(LLBZNO-LCO) is firstly proposed to improve the chemical stability and electrochemical properties of garnet with high-temperature processing.Small doses of LCO(3%) can significantly decrease the LCOISSE interface resistance from 121.2 to 10.1 Ω cm~2,while the sintering temperature of garnet-type LLBZNO decreases from 1230 to 1000℃.The all-solid-state battery based on the sintered LLBZNO-LCO SSE exhibits excellent cycling stability.Our approach achieves an enhanced LCOISSE interface and an improved sintering activity of garnet SSE,which provides a new strategy for optimizing the comprehensive performance of garnet SSE. | Xiaoye Liu Xiangkun Kong Wenyi Xiang Yining Jiang Bingqinq Xiong Weiwei Ping Changrong Xia Daoming Huan Chengwei Wang | 2023 | Journal of Energy Chemistry2023，，9： | 0 |
| 20 | Effects of iodoacetic acid drinking water disinfection byproduct on the gut microbiota and its metabolism in rats显示文摘Iodoacetic acid(IAA) is an unregulated disinfection byproduct in drinking water and has been shown to exert cytotoxicity, genotoxicity, tumorigenicity, and reproductive and developmental toxicity. However, the effects of IAA on gut microbiota and its metabolism are still unknown, especially the association between gut microbiota and the metabolism and toxicity of IAA. In this study, female and male Sprague–Dawley rats were exposed to IAA at 0 and 16 mg/kg bw/day daily for 8 weeks by oral gavage. Results of 16S r RNA gene sequencing showed that IAA could alter the diversity, relative abundance and function of gut microbiota in female and male rats. IAA also increased the abundance of genes related to steroid hormone biosynthesis in the gut microbiota of male rats. Moreover, metabolomics profiling revealed that IAA could significantly disturb 6 and 13 metabolites in the feces of female and male rats, respectively. In female rats, the level of androstanediol increased in the IAA treatment group. These results were consistent with our previous findings, where IAA was identified as an androgen disruptor. Additionally, the perturbed gut microbiota and altered metabolites were correlated with each other. The results of this study indicated that IAA could disturb gut microbiota and its metabolism. These changes in gut microbiota and its metabolism were associated with the reproductive and developmental toxicity of IAA. | Yujie Sha Huan Wu Yue Guo Xi Liu Yan Mo Qiyuan Yang Shumao Wei Kunling Long Du Lu Ying Xia Weiwei Zheng Zhiheng Su Xiao Wei | 2022 | Journal of Environmental Sciences2022，34，7： | 0 |
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