|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Rapamycin attenuates bleomycin-induced pulmonary fibrosis in rats and the expression of metalloproteinase-9 and tissue inhibitors of metalloproteinase-1 in lung tissue显示文摘 | Jin Xiaoguang | 2014 | Chinese Medical Journal2014,,7: | 20 |
| 2 | Precise nanomedicine for intelligent therapy of cancer显示文摘Precise nanomedicine has been extensively explored for efficient cancer imaging and targeted cancer therapy, as evidenced by a few breakthroughs in their preclinical and clinical explorations. Here, we demonstrate the recent advances of intelligent cancer nanomedicine, and discuss the comprehensive understanding of their structure-function relationship for smart and efficient cancer nanomedicine including various imaging and therapeutic applications, as well as nanotoxicity. In particular, a few emerging strategies that have advanced cancer nanomedicine are also highlighted as the emerging focus such as tumor imprisonment, supramolecular chemotherapy, and DNA nanorobot. The challenge and outlook of some scientific and engineering issues are also discussed in future development. We wish to highlight these new progress of precise nanomedicine with the ultimate goal to inspire more successful explorations of intelligent nanoparticles for future clinical translations. | Huabing Chen Zhanjun Gu Hongwei An Chunying Chen Jie Chen Ran Cui Siqin Chen Weihai Chen Xuesi Chen Xiaoyuan Chen Zhuo Chen Baoquan Ding Qian Dong Qin Fan Ting Fu Dayong Hou Qiao Jiang Hengte Ke Xiqun Jiang Gang Liu Suping Li Tianyu Li Zhuang Liu Guangjun Nie Muhammad Ovais Daiwen Pang Nasha Qiu Youqing Shen Huayu Tian Chao Wang Hao Wang Ziqi Wang Huaping Xu Jiang-Fei Xu Xiangliang Yang Shuang Zhu Xianchuang Zheng Xianzheng Zhang Yanbing Zhao Weihong Tan Xi Zhang Yuliang Zhao | 2018 | Science China Chemistry2018,61,12: | 19 |
| 3 | Cigarette smoking contributes to idiopathic pulmonary fibrosis associated with emphysema显示文摘 | Ye Qiao Huang Kewu Ding Yi Lou Baohui Hou Ziliang Dai Huaping Wang Chen | 2014 | Chinese Medical Journal2014,,3: | 10 |
| 4 | Clinical features and outcomes of 210 patients with idiopathic pulmonary fibrosis显示文摘 | Cai Miaotian Zhu Min Ban Chengjun Su Jin Ye Qiao Liu Yan Zhao Wen Wang Chen Dai Huaping | 2014 | Chinese Medical Journal2014,,10: | 8 |
| 5 | Microstructure Evolution and Tensile Properties of Ti_3Al/Ni-based Superalloy Welded Joint显示文摘In the present work,the dissimilar joining of a Ti_3AI-based alloy to a Ni-based superalloy was attempted by gas tungsten arc(GTA) welding technology.Sound joints were successfully achieved by using a Cu—Ni alloy as filler material.According to X-ray energy dispersive spectroscopy and X-ray diffraction analysis results three transitional layers at the weld/Ti_3AI interface were verified as follows:Ti_2AINb phase dissolved with Cu and Ni;AI(Cu,Ni)_2Ti,(Cu,Ni)_2Ti and(Nb,Ti) solid solution;Cu-rich phase and a complex multi-element phase.The In718/weld interface is characterized by solid solutions of Ni,Cu,Cr,Fe and Nb.The average tensile strength of the as-welded joints at room temperature is 1 63 MPa,and after a post—weld heat treatment it is increased slightly to 177 MPa.The fracture occurred at the surfacial layer of the joined Ti_3AI base alloy,indicating that the Ti_2AINb layer dissolved with Cu and Ni is the weak link of the Ti_3AI/ln71 8 joint. | Bingqing Chen Huaping Xiong Bingbing Sun Siyi Tang Shaoqing Guo Xuejun Zhang | 2014 | Journal of Materials Science & Technology2014,30,7: | 7 |
| 6 | Immunity-and-matrix-regulatory cells derived from human embryonic stem cells safely and effectively treat mouse lung injury and fibrosis显示文摘Lung injury and fibrosis represent the most significant outcomes of severe and acute lung disorders,including COVID-19.However,there are still no effective drugs to treat lung injury and fibrosis.In this study,we report the generation of clinical-grade human embryonic stem cells(hESCs)-derived immunity-and matrix-regulatory cells(IMRCs)produced under good manufacturing practice requirements,that can treat lung injury and fibrosis in vivo.We generate IMRCs by sequentially differentiating hESCs with serum-free reagents.IMRCs possess a unique gene expression profile distinct from that of umbilical cord mesenchymal stem cells(UCMSCs),such as higher expression levels of proliferative,immunomodulatory and anti-fibrotic genes.Moreover,intravenous delivery of IMRCs inhibits both pulmonary inflammation and fibrosis in mouse models of lung injury,and significantly improves the survival rate of the recipient mice in a dose-dependent manner,likely through paracrine regulatory mechanisms.IMRCs are superior to both primary UCMSCs and the FDA-approved drug pirfenidone,with an excellent efficacy and safety profile in mice and monkeys.In light of public health crises involving pneumonia,acute lung injury and acute respiratory distress syndrome,our findings suggest that IMRCs are ready for clinical trials on lung disorders. | Jun Wu Dingyun Song Zhongwen Li Baojie Guo Yani Xiao Wenjing Liu Lingmin Liang Chunjing Feng Tingting Gao Yanxia Chen Ying Li Zai Wang Jianyan Wen Shengnan Yang Peipei Liu Lei Wang Yukai Wang Liang Peng Glyn Nigel Stacey Zheng Hu Guihai Feng Wei Li Yan Huo Ronghua Jin Ng Shyh-Chang Qi Zhou Liu Wang Baoyang Hu Huaping Dai Jie Hao | 2020 | Cell Research2020,30,9: | 7 |
| 7 | Extracorporeal blood therapy in sepsis and acute respiratory distress syndrome: the "purifying dream"显示文摘 | Xu Xuefeng Dai Huaping Jia Chun'e Wang Chen | 2014 | Chinese Medical Journal2014,,24: | 6 |
| 8 | Hyperglycemic memory in diabetic cardiomyopathy显示文摘Cardiovascular diseases account for approximately 80%of deaths among individuals with diabetes mellitus,with diabetic cardiomyopathy as the major diabetic cardiovascular complication.Hyperglycemia is a symptom that abnormally activates multiple downstream pathways and contributes to cardiac hypertrophy,fibrosis,apoptosis,and other pathophysiological changes.Although glycemic control has long been at the center of diabetes therapy,multicenter randomized clinical studies have revealed that intensive glycemic control fails to reduce heart failure-associated hospitalization and mortality in patients with diabetes.This finding indicates that hyperglycemic stress persists in the cardiovascular system of patients with diabetes even if blood glucose level is tightly controlled to the normal level.This process is now referred to as hyperglycemic memory(HGM)phenomenon.We briefly reviewed herein the current advances that have been achieved in research on the underlying mechanisms of HGM in diabetic cardiomyopathy. | Jiabing Zhan Chen Chen Dao Wen Wang Huaping Li | 2022 | Frontiers of Medicine2022,16,1: | 6 |
| 9 | Single-cell RNA sequencing profiling of the effects of aging on alveolar stem cells显示文摘The aging of alveolar stem cells has been linked to many chronic lung diseases, including pulmonary fibrosis. However, the effects of aging on alveolar stem cells during homeostasis and post-injury alveolar repair have not been well characterized. Here we conducted a single-cell RNA sequencing(scRNA-seq) analysis of alveolar stem cells of 3-month-old and 12-month-old mice to characterize the aging effect on alveolar stem cells. Our results have shown that the transcriptomes of alveolar stem cells of 3-month-old and 12-month-old mice are not significantly different under the steady condition. However, after a bleomycin-induced lung injury, the alveolar stem cells of 12-month-old mice show enhanced inflammatory responses and decreased lipid metabolism. Our study suggests a close relationship among aging, lipid metabolism, inflammatory responses and chronic lung diseases. | Tingting Lv Kewu Jiang Jiawen Wang Nan Tang Huaping Dai Chen Wang | 2019 | Science China(Life Sciences)2019,62,8: | 6 |
| 10 | Clinicopathological analysis of metaplastic meningioma: report of 15 cases in Huashan Hospital显示文摘Objective: Metaplastic meningioma is a rare subtype of benign meningiomas, classified as WHO grade I with well prognosis. Here we presented our experiences on 15 cases of metaplastic meningioma, to investigate the clinicopathological features, therapies and prognosis of these cases. Methods: 15 patients underwent surgical treatment for intracranial metaplastic meningioma between 2001 and 2010 at Neurosurgery Department of Huashan Hospital, Shanghai, China. The clinical data, radiological manifestation, treatment strategy, pathological findings and prognosis of all patients were analyzed retrospectively. Results: Among the 15 cases (10 males and 5 females), the age ranged from 22 to 74 years old (the mean age was 50.67-year old). The clinical manifestations include headache, dizziness, seizure attack, vision decrease, and weakness of bilateral lower limbs. All the patients received surgical treatment, combined with radiotherapy in some cases. In the follow-up period, recurrence occurred in 2 cases, of which 1 patient died of other system complications. Conclusions: Metaplastic meningiomas are characterized by focal or widespread mesenchymal differentiation with formation of bone, cartilage, fat, and xanthomatous tissue elements. Surgical removal is the optimal therapy, and the overall prognosis is well. But recurrence may occur in some cases, thus radiotherapy is necessary for such kind of patients. | Hailiang Tang Huaping Sun Hong Chen Ye Gong Ying Mao Qing Xie Liqian Xie Mingzhe Zheng Daijun Wang Hongda Zhu Xiaoming Che Ping Zhong Kang Zheng Shiqi Li Weimin Bao Jianhong Zhu Xuanchun Wang Xiaoyuan Feng Xiancheng Chen Liangfu Zhou | 2013 | Chinese Journal of Cancer Research2013,25,1: | 6 |
| 11 | Nuclear miR-665 aggravates heart failure via suppressing phosphatase and tensin homolog transcription显示文摘Although numerous miRNAs have been discovered,their functions in the different subcellular organelles have remained obscure.In this study,we found that miR-665 was enriched in the nucleus of cardiomyocytes,and then investigated the underlying role of nuclear miR-665 in heart failure.RNA fluorescence in situ hybridization assays in human heart tissue sections and primary cardiomyocytes showed that miR-665 was localized in the nucleus of cardiomyocytes.Increased expression of nuclear miR-665 was observed not only in the cardiomyocytes isolated from the heart of mice treated in vivo by transverse aortic constriction(TAC),but also in phenylephrine(PE)-treated cultured cardiomyocytes in vitro.To further explore the role of miR-665 in heart failure,a type 9 recombinant adeno-associated virus(rAAV)system was employed to manipulate the expression of miR-665 in mice.Overexpression of miR-665 aggravated TAC-induced cardiac dysfunction,while down-expression of miR-665 showed opposite effects.Bioinformatic prediction and biological validation confirmed that the PTEN(phosphatase and tensin homolog)gene was one of the targets of miR-665 in the nucleus.Furthermore,restoring PTEN expression significantly eliminated the destructive effects of miR-665 over-expression in TAC-induced cardiac dysfunction.Our data showed that nuclear miR-665 aggravates heart failure via inhibiting PTEN expression,which provided a therapeutic approach for heart failure. | Jiahui Fan Xudong Zhang Xiang Nie Huaping Li Shuai Yuan Beibei Dai Jiabing Zhan Zheng Wen Jiangang Jiang Chen Chen Daowen Wang | 2020 | Science China(Life Sciences)2020,63,5: | 4 |
| 12 | The double face of miR-320:cardiomyocytes-derived miR-320 deteriorated while fibroblasts-derived miR-320 protected against heart failure induced by transverse aortic constriction显示文摘MicroRNAs(miRNAs)are aberrantly expressed in the pathophysiologic process of heart failure(HF).However,the functions of a certain miRNA in different cardiac cell types during HF are scarcely reported,which might be covered by the globe effects of it on the heart.In the current study,Langendorff system was applied to isolate card io myocytes(CMs)and cardiac fibroblasts(CFs)from transverse aortic constriction(TAC)-induced mice.Slight increase of miR-320 expression was observed in the whole heart tissue of TAC mice.Interestingly,miR-320 was significantly elevated in CMs but decreased in CFs from TAC mice at different time points.Then,recombinant adeno-associated virus 9 with cell-type-specific promoters were used to manipulate miR-320 expressions in vivo.Both in vitro and in vivo experiments showed the miR-320 overexpression in CMs exacerbated cardiac dysfunction,whereas overexpression of miR-320 in CFs alleviated cardiac fibrosis and hypertrophy.Mechanically,downstream signaling pathway analyses revealed that miR-320 might induce various effects via targeting PLEKHM3 and IFITM1 in CMs and CFs,respectively.Moreover,miR-320 mediated effects could be abolished by PLEKHM3 re-expression in CMs or IFITM1 re-expression in CFs.Interestingly,miR-320 treated CFs were able to indirectly affect CMs function,but not vice versa.Meanwhile,upstream signaling pathway analyses showed that miR-320 expression and decay rate were rigorously manipulated by Ago2,which was regulated by a cluster of cell-type-specific TFs distinctively expressed in CMs and CFs,respectively.Together,we demonstrated that miR-320 functioned differently in various cell types of the heart during the progression of HF. | Xudong Zhang Shuai Yuan Huaping Li Jiabing Zhan Feng Wang Jiahui Fan Xiang Nie Yan Wang Zheng Wen Yanghui Chen Chen Chen Dao Wen Wang | 2021 | Signal Transduction and Targeted Therapy2021,6,3: | 4 |
| 13 | Large eddy simulation of unsteady transitional flow on the low-pressure turbine blade显示文摘The aim of this paper is to predict the phenomenon of laminar separation,transition and reattachment in a low-pressure turbine(LPT).Self-developed large eddy simulation program of compressible N-S equations was used to describe the flow structures of T106A LPT blade profile at Reynolds number of 1.1X105 based on the exit isentropic velocity and chord length.The computational results show the distributions of time-averaged wall-static pressure coefficient and mean skin-friction coefficient on the blade surface.The locations of laminar separation and reattachment points occur around 87%and 98%axial chord,which agree well with experiment data.The two-dimensional shear layer is gradually unstable along the downstream half of the suction side as a result of the spanwise fluctuation and the roll up of shear layer via Kelvin-Helmholtz(KH)instability.Three-dimensional motions appear near 84%axial chord which later triggers spanwise vortexes and streamwise vortexes,leading to transition to turbulence in the separation bubble.Through introducing the concept of dissipation function,the high loss mainly comes from the places where strong shear layer and intense fluctuation exist.Furthermore,the separation region is only an accumulation center of the low-energy fluid rather than an area of loss source. | WANG YunFei CHEN Fu LIU HuaPing CHEN HuanLong | 2014 | Science China(Technological Sciences)2014,57,9: | 4 |
| 14 | Atomic-scale observation of a two-stage oxidation process in Cu2O显示文摘Cu 2 O nanocrystallines (NC ) 直接被观察由在 situ 高分辨率的传播电子显微镜学。一个二阶段的氧化过程被观察:(1 ) 起始的氧化阶段被 Cu 2 经由稳固固体的转变的 O NC,导致一个新中间的 CuO x 阶段的形成。CuO x 阶段的可能的水晶结构被讨论。(2 ) 随后, CuO x 被 layer-by-layer 氧化转变成 CuO。这些结果将在理解铜氧化物的氧化机制帮助并且为改进他们的结构的差异并且利用他们的潜在的工业应用铺平道路。 | Huihui Liu He Zheng Lei Li Huaping Sheng Shuangfeng Jia Fan Cao Xi Liu Boyun Chen Ru Xing Dongshan Zhao Jianbo Wang | 2017 | Nano Research2017,10,7: | 4 |
| 15 | Intraoperative ultrasound assistance in resection of intracranial meningiomas显示文摘Objective: Intracranial meningiomas, especially those located at anterior and middle skull base, are difficult to be completely resected due to their complicated anatomy structures and adjacent vessels. It's essential to locate the tumor and its vessels precisely during operation to reduce the risk of neurological deficits. The purpose of this study was to evaluate intraoperative ultrasonography in displaying intracranial meningioma and its surrounding arteries, and evaluate its potential to improve surgical precision and minimize surgical trauma. Methods: Between December 2011 and January 2013, 20 patients with anterior and middle skull base meningioma underwent surgery with the assistance of intraoperative ultrasonography in the Neurosurgery Department of Shanghai Huashan Hospital. There were 7 male and 13 female patients, aged from 31 to 66 years old. Their sonographic features were analyzed and the advantages of intraoperative ultrasonography were discussed. Results: The border of the meningioma and its adjacent vessels could be exhibited on intraoperative ultrasonography. The sonographic visualization allowed the neurosurgeon to choose an appropriate approach before the operation. In addition, intraoperative ultrasonography could inform neurosurgeons about the location of the tumor, its relation to the surrounding arteries during the operation, thus these essential arteries could be protected carefully. Conclusions: Intraoperative ultrasonography is a useful intraoperative technique. When appropriately applied to assist surgical procedures for intracranial meningioma, it could offer very important intraoperative information (such as the tumor supplying vessels) that helps to improve surgical resection and therefore might reduce the postoperative morbidity. | Hailiang Tang Huaping Sun Liqian Xie Qisheng Tang Ye Gong Ying Mao Qing Xie Mingzhe Zheng Daijun Wang Hongda Zhu Jianhong Zhu Xiaoyuan Feng Zhenwei Yao Xiancheng Chen Liangfu Zhou | 2013 | Chinese Journal of Cancer Research2013,25,3: | 3 |
| 16 | Systematic study on the mechanical and electric behaviors of the nonbuckling interconnect design of stretchable electronics显示文摘Recently, we developed a nonbuckling interconnect design that provides an effective approach to simultaneously achieving high elastic stretchability, easiness for encapsulation, and high electric performance for stretchable electronics. This paper aims to systematically study its mechanical and electric behaviors, including comparisons of the nonbuckling and buckling interconnect designs on stretchability, effects of the thickness on electric performance, and modeling and experimental investigations on the finite deformation mechanics. It is found that the results on stretchability depend on the layouts. Long straight segments and small arc radii for nonbuckling interconnects yield an enhancement of stretchability, which is much better than that of buckling designs. On the other hand, shorter straight segments or thicker interconnects are better to lower the resistances of interconnects.Therefore, optimization of the designs needs to balance the requirements of both the mechanical and electric performances. The finite deformation of interconnects during stretching is analyzed. The established analytic model is well validated by both the finite element modeling and experimental investigations. This work is key for providing the design guidelines for nonbucklingbased stretchable electronics. | Hao Liu RiYe Xue JianQiao Hu XueCheng Ping HuaPing Wu MingQi Huang Han Zhang Xu Guo Rui Li YuLi Chen YeWang Su | 2018 | Science China(Physics,Mechanics & Astronomy)2018,61,11: | 3 |
| 17 | Target-triggered inhibiting oxidase-mimicking activity of platinum nanoparticles for ultrasensitive colorimetric detection of silver ion显示文摘The development of efficient methods for the detection of hazardous and toxic elements is extremely important for environmental security and public health. In this work, we developed a facile colorimetric assaying system for Ag+ detection in aqueous solution. Chitosan-stabilized platinum nanoparticles(ChPtNPs) were synthesized and severed as an artificial oxidase to catalyze the oxidation of the substrate3,30,5,50-tetramethylbenzidine(TMB) and generate color signal. In the presence of Ag+, due to the strong metallophilic interactions between Ag+ and Pt2+ on the surface of Ch-PtNPs, Ag+ can weaken the affinity to the substrates and inactivate the catalytic activity of Ch-PtNPs, leading to decreased absorbance signal to varying degrees depending on Ag+ amount. Combing the specific binding between Ch-PtNPs and Ag+ with signal amplification procedure based on the Ch-PtNPs-catalyzed TMB oxidation, a sensitive,selective, simple, cost-effective, and rapid detection method for Ag+ can be realized. Ag+ ions in tap and lake waters have been successfully detected. We ensured that the proposed method can be a potential alternative for Ag+ determination in environmental samples. | Haohua Deng Shaobin He Xiuling Lin Lu Yang Zhen Lin Ruiting Chen Huaping Peng Wei Chen | 2019 | Chinese Chemical Letters2019,30,9: | 3 |
| 18 | Microstructures and mechanical properties of Ti_3Al/Ni-based superalloy joints arc welded with Ti–Nb and Ti–Ni–Nb filler alloys显示文摘Dissimilar joining of Ti3Al-based alloy to Ni-based superalloy has been carried out using gas tungsten arc(GTA) welding technology with Ti–Nb and Ti–Ni–Nb filler alloys.The joint welded with the Ti–Nb filler alloy contained much less interfacial brittle phases than the one using the Ti–Ni–Nb filler alloy.The average room-temperature tensile strength of the joint welded with Ti–Nb was 202 MPa and the strength value of the one welded with Ti–Ni–Nb was 128 MPa.For both fillers,the weak links of the dissimilar joints were the weld/In718 interfaces.The presence of TiNi,TiNi3 and Ni3Nb intermetallic compounds in the joint welded with Ti–Ni–Nb induced microcracks at the weld/In718 interface and deteriorated the mechanical properties of the joint.And the adoption of the Ti–Nb filler alloy decreased the formation tendency of interfacial brittle phases to some extent and thus enhanced the tensile strength of the joint. | Bingqing Chen Huaping Xiong Bingbing Sun Siyi Tang Borui Du Neng Li | 2014 | Progress in Natural Science:Materials International2014,24,4: | 3 |
| 19 | Durable and Flexible Bio-assembled RGO-BC/BC Bilayer Electrodes for Pressure Sensing显示文摘The new generation of electronics tends to be well-performed,facile and environmentally friendly.Here,we report a bio-assembled sensitive pressure senor based on reduced graphene oxide-bacterial cellulose/bacterial cellulose(RGO-BC/BC)bilayer films,integrated by bacteria in one step.The advantage of this integration is that there is strong nanofiber connection between the conductive RGO-BC and insulative highly compressible porous BC layer,which confers RGO-BC/BC film electrode with good robustness,tailorability,flexibility and wearability.Without extra bonding-interface or postprocessing,the RGO-BC/BC bilayer films could be directly assembled into pressure sensing devices.Ascribed from the good reversible compressibility of the BC layer and incorporated bilayer structure,the pressure sensor performs good sensitivity and excellent durability and bending stability.The facile sensitive capacitive sensor could monitor the human hand or finger motion in real time.The sensing array is able to detect the spatial distribution of pressure mounted in the flat plane as well as curved surface of human body,succeeding in the correction of human walking posture for health care.The e-skins are potential in wearable electronics,artificial intelligence,soft robots,healthcare etc. | Fangyi Guan Zhiliang Han Mengtian Jin Zhuotong Wu Ye Chen Shiyan Chen Huaping Wang | 2021 | Advanced Fiber Materials2021,3,2: | 2 |
| 20 | Intestinal dysbiosis exacerbates the pathogenesis of psoriasis-like phenotype through changes in fatty acid metabolism显示文摘The intestinal microbiota has been associated with host immunity as well as psoriasis;however,the mechanism of intestinal microbiota regulating psoriasis needs to be demonstrated systematically.Here,we sought to examine its role and mechanism of action in the pathogenesis of psoriasis.We found that the severity of psoriasis-like skin phenotype was accompanied by changes in the composition of the intestinal microbiota.We performed co-housing and fecal microbial transplantation(FMT)experiments using the K14-VEGF transgenic mouse model of psoriasis and demonstrated that the transfer of intestinal microbiota from mice with severe psoriasis-like skin phenotype exacerbated psoriasiform skin inflammation in mice with mild symptoms,including increasing the infiltration and differentiation of Th17,and increased the abundance of Prevotella,while decreasing that of Parabacteroides distasonis,in the colon.These alterations affected fatty acid metabolism,increasing the abundance of oleic and stearic acids.Meanwhile,gentamicin treatment significantly reduced the abundance of Prevotella and alleviated the psoriasis-like symptoms in both K14-VEGF mice and imiquimod(IMQ)-induced psoriasis-like mice.Indeed,administration of oleic and stearic acids exacerbated psoriasis-like symptoms and increased Th17 and monocyte-derived dendritic cell infiltration in the skin lesion areas in vivo,as well as increased the secretion of IL-23 by stimulating DCs in vitro.At last,we found that,treatment of PDE-4 inhibitor alleviated psoriasis-like phenotype of K14-VEGF mice accompanied by the recovery of intestinal microbiota,including the decrease of Prevotella and increase of Parabacteroides distasonis.Overall,our findings reveal that the intestinal microbiota modulates host metabolism and psoriasis-like skin inflammation in mice,suggesting a new target for the clinical diagnosis and treatment of psoriasis. | Qixiang Zhao Jiadong Yu Hong Zhou Xiaoyan Wang Chen Zhang Jing Hu Yawen Hu Huaping Zheng Fanlian Zeng Chengcheng Yue Linna Gu Zhen Wang Fulei Zhao Pei Zhou Haozhou Zhang Nongyu Huang Wenling Wu Yifan Zhou Jiong Li | 2023 | Signal Transduction and Targeted Therapy2023,8,2: | 2 |