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| 1 | Efficient generation of hepatocyte-like cells from human induced pluripotent stem cells显示文摘人的导致的 pluripotent 茎(iPS ) 房间类似于胚胎的茎(ES ) 房间,和罐头强烈地增殖并且区分进许多房间类型。然而,人的 iPS 房间的肝的区别还没被报导了。在这份报告,人的 iPS 房间被导致由一个逐步的协议区分进肝的房间。肝房间标记的表达式和人的 iPS 的肝相关的函数导出房间的房间被监视并且与区分的人的 ES 房间和主要人的 hepatocytes 的相比。在白天 7 点的约 60% 区分的人的 iPS 房间表示了肝的标记 alpha fetoprotein 和白长袍的。在白天 21 点的区分的房间包括白朊 Asecretion,肝糖合成,脲生产和可诱导的细胞色素 P450 活动展出了肝房间功能。肝的标记的表示和 iPS 的肝相关的功能导出房间的肝的房间比得上人的 ES 导出房间的肝的房间的。这些结果证明人的 iPS 房间,类似于人的 ES 房间,能高效地被导致区分房间进象 hepatocyte 一样。 | Zhihua Song Jun Cai Yanxia Liu Dongxin Zhao Jun Yong Shuguang Duo Xijun Song Yushan Guo Yang Zhao Han Qin Xiaolei Yin Chen Wu Jie Che Shichun Lu Mingxiao Ding Hongkui Deng | 2009 | Cell Research2009，19，11： | 63 |
| 2 | Over-expression of WOX1 Leads to Defects in Meristem Development and Polyamine Homeostasis in Arabidopsis显示文摘In plants,the meristem has to maintain a separate population of pluripotent cells that serve two main tasks,i.e.,self-maintenance and organ initiation,which are separated spatially in meristem.Prior to our study,WUS and WUS-like WOX genes had been reported as essential for the development of the SAM.In this study,the consequences of gain of WOX1 function are described.Here we report the identification of an Arabidopsis gain-of-function mutant wox1-D,in which the expression level of the WOX1(WUSCHEL HOMEOBOX 1) was elevated and subtle defects in meristem development were observed.The wox1-D mutant phenotype is dwarfed and slightly bushy,with a smaller shoot apex.The wox1-D mutant also produced small and dark green leaves,and exhibited a failure in anther dehiscence and male sterility.Molecular evidences showed that the transcription of the stem cell marker gene CLV3 was down-regulated in the meristem of wox1-D but accumulated in the other regions,i.e.,in the root-hypocotyl junction and at the sites for lateral root initiation.The fact that the organ size and cell size in leaves of wox1-D are smaller than those in wild type suggests that cell expansion is possibly affected in order to have partially retarded the development of lateral organs,possibly through alteration of CLV3 expression pattern in the meristem.An S-adenosylmethionine decarboxylase(SAMDC) protein,SAMDC1,was found able to interact with WOX1 by yeast two-hybrid and pull-down assays in vitro.HPLC analysis revealed a significant reduction of polyamine content in wox1-D.Our results suggest that WOX1 plays an important role in meristem development in Arabidopsis,possibly via regulation of SAMDC activity and polyamine homeostasis,and/or by regulating CLV3 expression. | Yanxia Zhang Renhong Wu Genji Qin Zhangliang Chen Hongya Gu Li-Jia Qu | 2011 | Journal of Integrative Plant Biology2011，53，6： | 23 |
| 3 | Porous LiF layer fabricated by a facile chemical method toward dendrite-free lithium metal anode显示文摘Lithium metal is supposed to be critical material for constructing next-generation batteries due to extremely high capacity and ultralow redox potential. However, the perplexing issue of lithium dendrite growth impedes the commercial application. The initial nucleation and low Li ions diffusion rate in the electrolyte/electrode interface dominate the deposition behavior. Therefore, a uniform and flexible interface is urgently needed. Here, a facile method is proposed to prepare a thin and porous LiF-rich layer (TPL) by the in-situ reaction of small amount of ammonium hydrogen difluoride (NH4HF2) and Li metal. The deposition morphology on Li metal anode with LiF layer is significantly flat and homogeneous owning to low lateral diffusion barrier on LiF crystals and the porous structure of TPL film. Additionally, the symmetrical cells made with such TPL Li anodes show significantly stable cycling over 100 cycles at high current density of 6 mA/cm^2. The TPL Li|LiFePO4 full cells keep over 99% capacity retention after 100 cycles at 2.0 C. This approach serves as a facile and controllable way of adjusting the protective layer on Li metal. | Yanxia Yuan Feng Wu Guanghai Chen Ying Bai Chuan Wu | 2019 | Journal of Energy Chemistry2019，28，10： | 14 |
| 4 | Evaluating and Improving Wind Forecasts over South China: The Role of Orographic Parameterization in the GRAPES Model显示文摘Unresolved small-scale orographic(SSO) drags are parameterized in a regional model based on the Global/Regional Assimilation and Prediction System for the Tropical Mesoscale Model(GRAPES TMM). The SSO drags are represented by adding a sink term in the momentum equations. The maximum height of the mountain within the grid box is adopted in the SSO parameterization(SSOP) scheme as compensation for the drag. The effects of the unresolved topography are parameterized as the feedbacks to the momentum tendencies on the first model level in planetary boundary layer(PBL)parameterization. The SSOP scheme has been implemented and coupled with the PBL parameterization scheme within the model physics package. A monthly simulation is designed to examine the performance of the SSOP scheme over the complex terrain areas located in the southwest of Guangdong. The verification results show that the surface wind speed bias has been much alleviated by adopting the SSOP scheme, in addition to reduction of the wind bias in the lower troposphere. The target verification over Xinyi shows that the simulations with the SSOP scheme provide improved wind estimation over the complex regions in the southwest of Guangdong. | Shuixin ZHONG Zitong CHEN Daosheng XU Yanxia ZHANG | 2018 | Advances in Atmospheric Sciences2018，35，6： | 12 |
| 5 | Holocene vegetation cover in Qin’an area of western Chinese Loess Plateau revealed by n-alkane显示文摘Previous studies have found that wetlands prevailed in western Chinese Loess Plateau and pine pollen could reach up to 80% in Qin’an area of the plateau during middle Holocene. It was then deduced that forest vegetation covered Qin’an area in a warm and wet climate during middle Holocene. The proxies of molecule biomarkers from two Holocene sections, a swamp-alluvial loess section and a typical loess-paleosol section are used to reconstruct regional vegetation history. It is found that the heavy-molecular-weight (HMW) homologues of the n-alkanes in all samples exhibit a pronounced odd-over-even predominance, maximizing at C31 and the abundance of the nC27-alkanes is the lowest in nC27, nC29, nC31, i.e. C27 | ZHONG YanXia CHEN FaHu AN ChengBang XIE ShuCheng HUANG XianYu | 2007 | Chinese Science Bulletin2007，52，12： | 10 |
| 6 | Effectiveness of Jinying capsule on pelvic inflammatory disease in patients with symptom pattern of damp and heat accumulation: a double-blinded, multicenter, randomized, placebo-controlled clinical trial显示文摘OBJECTIVE: To evaluate the therapeutic effectiveness and safety of Jinying capsule on pelvic inflammatory disease(PID) in patients with symptoms identified as the pattern of damp and heat accumulation in terms of Traditional Chinese Medicine(TCM).METHODS: We conducted a double-blinded, multicenter, randomized, placebo-controlled clinical trial which included 155 patients diagnosed with PID and identified as symptom pattern of damp and heat accumulation. They were randomly divided into experimental group(n = 78) and control group(n = 77) according to a random number table. The treatment lasted for a period of 28 d. The experimental group was given Jinying capsules and oral levofloxacin plus oral metronidazole for first 7 d.They continued with Jinying capsules and levofloxacin placebo and metronidazole placebo for another 7 d. For the remaining 14 d, they continued with Jinying capsules only. Whereas, the control group was treated with oral levofloxacin and metronidazole and Jinying capsule placebo for the first 14 d in the same way as the experimental group and then continued with Jinying capsule placebo only for the remaining 14 d. The clinical efficacy was assessed using McCormack scale, TCM symptom pattern scores, physicochemical indexes including white blood cell and erythrocyte sedimentation rate, C-reaction protein, smear of vaginal discharge,and pelvic ultrasound.RESULTS: Comparing McCormack scale between both groups after treatment, the difference in curative effect between both groups was significant (P = 0.0269). The cure rate of the experimental group and control group is 76.32% and 59.46% respectively at week 4. Comparing TCM symptom pattern scores between both groups before and after treatment, the differences in total effective rate were both significant(P < 0.05). The curative effect rate of experimental group is 2.63% and 13.70% of the control group at week 1(P = 0.0131), and73.33% of the experimental group and 56.94% of the control group at week 4(P = 0.0369). No significant differences were found between the two groups on the Physicochemical indexes(all P >0.05). No adverse events or reactions occurred in the experimental groups.CONCLUSION: Jinying capsule can reduce the dosage of antibiotics needed for PID treatment, and improve the symptoms in PID patients. | Yang Yan Lu Yao Zhou Deping Pei Fenglan Li Qin Chen Shuqiong Wang Qiufeng Wang Yanting Jin Zhe Liu Yanxia | 2020 | Journal of Traditional Chinese Medicine2020，40，3： | 10 |
| 7 | Developing superior alleles of yield genes in rice by artificial mutagenesis using the CRISPR/Cas9 system显示文摘Rice yield is an important and complex agronomic trait controlled by multiple genes.In recent decades,dozens of yield-associated genes in rice have been cloned,many of which can increase production in the form of loss or degeneration of function.However,mutations occurring randomly under natural conditions have provided very limited genetic resources for yield increases.In this study,potentially yield-increasing alleles of two genes closely associated with yield were edited artificially.The recently developed CRISPR/Cas9system was used to edit two yield genes:Grain number 1a(Gn1a)and DENSE AND ERECT PANICLE1(DEP1).Several mutants were identified by a target sequence analysis.Phenotypic analysis confirmed one mutant allele of Gn1a and three of DEP1 conferring yield superior to that conferred by other natural high-yield alleles.Our results demonstrate that favorable alleles of the Gnla and DEP1 genes,which are considered key factors in rice yield increases,could be developed by artificial mutagenesis using genome editing technology. | Liyu Huang Ru Zhang Guangfu Huang Yanxia Li Getachew Melaku Shilai Zhang Haitao Chen Yanjuan Zhao Jing Zhang Yesheng Zhang Fengyi Hu | 2018 | The Crop Journal2018，6，5： | 8 |
| 8 | Effect of Banxia Xiexin decoction on Helicobacter pylori-related peptic ulcers and its possible mechanism via the TGF-β/Smad signaling pathway显示文摘OBJECTIVE: To investigate the effect of Banxia Xiexin decoction(BXD) on Helicobacter pylori(Hp)-related peptic ulcers(PUs) and the possible mecha-nism underlying BXD actions via the transforming growth factor-β/small mothers against decapentaplegic(TGF-β/Smad) signaling pathway.METHODS: PU patients with cold-heat complex syndrome were randomly assigned to groups that received Chinese or Western medicines with 20 patients in each group. Serum was collected after 7 d of treatment. The healthy group included 20 individuals. Gastric mucosal epithelial cell line GES-1 was cultured in vitro and randomly divided into the following seven groups: control, model, healthy,Western Medicine, prior treatment, low dosage,and high dosage. After 72 h of treatment with the corresponding serum, the m RNA and protein expression levels of TGF-β1, Smad3, and Smad7 were measured by reverse transcription quantitative polymerase chain reaction and western blotting, respectively.RESULTS: The m RNA expression levels of TGF-β1 and Smad3 in GES-1 cells were increased after Hp introduction, and these increased levels were reduced by the BXD-containing serum. The protein levels of p-Smad3, but not TGF-β1 or Smad3, were significantly increased in Hp-treated GES-1 cells,and treatment with the BXD-containing serum markedly decreased the protein levels. Smad7 expression was significantly enhanced following treatment with the BXD-containing serum at transcriptional and protein levels in a dose-dependent manner.CONCLUSION: BXD regulates the TGF-β/Smad signaling pathway by inhibiting the expression of TGF-β1 and Smad3, and increasing the expression of Smad7. | Chen Shaofang Liang Huiqing Chen Shaodong Huang Yanping Wan Shichuan Huang Yanxia | 2018 | Journal of Traditional Chinese Medicine2018，38，3： | 7 |
| 9 | Release of VEGF and BMP9 from injectable alginate based composite hydrogel for treatment of myocardial infarction显示文摘Myocardial infarction(MI)is one of cardiovascular diseases that pose a serious threat to human health.The pathophysiology of MI is complex and contains several sequential phases including blockage of a coronary artery,necrosis of myocardial cells,inflammation,and myocardial fibrosis.Aiming at the treatment of different stages of MI,in this work,an injectable alginate based composite hydrogel is developed to load vascular endothelial active factor(VEGF)and silk fibroin(SF)microspheres containing bone morphogenetic protein 9(BMP9)for releasing VEGF and BMP9 to realize their respective functions.The results of in vitro experiments indicate a rapid initial release of VEGF during the first few days and a relatively slow and sustained release of BMP9 for days,facilitating the formation of blood vessels in the early stage and inhibiting myocardial fibrosis in the long-term stage,respectively.Intramyocardial injection of such composite hydrogel into the infarct border zone of mice MI model via multiple points promotes angiogenesis and reduces the infarction size.Taken together,these results indicate that the dual-release of VEGF and BMP9 from the composite hydrogel results in a collaborative effect on the treatment of MI and improvement of heart function,showing a promising potential for cardiac clinical application. | Yong Wu Tianqi Chang Weiqian Chen Xiaoyu Wang Jingjing Li Yueqiu Chen You Yu Zhenya Shen Qian Yu Yanxia Zhang | 2021 | Bioactive Materials2021，6，2： | 7 |
| 10 | Immunity-and-matrix-regulatory cells derived from human embryonic stem cells safely and effectively treat mouse lung injury and fibrosis显示文摘Lung injury and fibrosis represent the most significant outcomes of severe and acute lung disorders,including COVID-19.However,there are still no effective drugs to treat lung injury and fibrosis.In this study,we report the generation of clinical-grade human embryonic stem cells(hESCs)-derived immunity-and matrix-regulatory cells(IMRCs)produced under good manufacturing practice requirements,that can treat lung injury and fibrosis in vivo.We generate IMRCs by sequentially differentiating hESCs with serum-free reagents.IMRCs possess a unique gene expression profile distinct from that of umbilical cord mesenchymal stem cells(UCMSCs),such as higher expression levels of proliferative,immunomodulatory and anti-fibrotic genes.Moreover,intravenous delivery of IMRCs inhibits both pulmonary inflammation and fibrosis in mouse models of lung injury,and significantly improves the survival rate of the recipient mice in a dose-dependent manner,likely through paracrine regulatory mechanisms.IMRCs are superior to both primary UCMSCs and the FDA-approved drug pirfenidone,with an excellent efficacy and safety profile in mice and monkeys.In light of public health crises involving pneumonia,acute lung injury and acute respiratory distress syndrome,our findings suggest that IMRCs are ready for clinical trials on lung disorders. | Jun Wu Dingyun Song Zhongwen Li Baojie Guo Yani Xiao Wenjing Liu Lingmin Liang Chunjing Feng Tingting Gao Yanxia Chen Ying Li Zai Wang Jianyan Wen Shengnan Yang Peipei Liu Lei Wang Yukai Wang Liang Peng Glyn Nigel Stacey Zheng Hu Guihai Feng Wei Li Yan Huo Ronghua Jin Ng Shyh-Chang Qi Zhou Liu Wang Baoyang Hu Huaping Dai Jie Hao | 2020 | Cell Research2020，30，9： | 7 |
| 11 | Extraction of hydrogen chloride by a coupled reaction-solvent extraction process显示文摘A coupled 反应溶剂抽取过程被用来把 HCl 从模仿的蒸馏器浪费移开。各种各样的提炼之物和 diluents 的抽取表演被比较,在各种各样的 diluents 的 N235 (第三级的胺的混合物) 的明显的盐基度是坚定的。最好的结果作为提炼之物用 N235 和 isoamyl 酒精被获得并且稀释分别地。从联合抽取的 HCl 的收益与这个抽取系统是 75% 。为在两个的 HCl 的移动的机制直接、联合的抽取被调查。为联合抽取, R 3 NHCl 离子对建筑群涉及 HCl 移动。为直接抽取,机制在 HCl 的高集中包含了氢契约的形成。 | Yunzhao Li Xingfu Song Guilan Chen Shuying Sun Yanxia Xu Jianguo Yu | 2015 | Frontiers of Chemical Science and Engineering2015，9，4： | 6 |
| 12 | Base editing-mediated splicing correction therapy for spinal muscular atrophy显示文摘Dear Editor,Spinal muscular atrophy(SMA)is a devastating autosomal recessive motor neuron disease.1,2 Infants with more severe forms of type I SMA die before the age of 2 if no intervention is provided.1,2 Spinraza and zolgensma have been approved by the FDA as SMA therapeutics for pediatric patients.1,2 However,as an antisense oligonucleotide(ASO)based therapy,spinraza requires four loading doses,followed by three annual maintenance doses.The patients would be subjected to repeated intrathecal injections in the procedure.Zolgensma is a single-dose gene-replacement therapy for SMA,but unfortunately is unreliable in maintaining a high,stable level of gene expression.These issues have limited the therapeutic effects of the two approved drugs for SMA. | Xiang Lin Haizhu Chen Ying-Qian Lu Shunyan Hong Xinde Hu Yanxia Gao Lu-Lu Lai Jin-Jing Li Zishuai Wang Wenqin Ying Lixiang Ma Ning Wang Erwei Zuo Hui Yang Wan-Jin Chen | 2020 | Cell Research2020，30，6： | 5 |
| 13 | N-doped graphene and TiO_2 supported manganese and cerium oxides on low-temperature selective catalytic reduction of NO_x with NH_3显示文摘A series of N-doped graphene(NG)and TiO_2 supported MnO_x–CeO_2 catalysts were prepared prepared by a hydrothermal method.The catalysts with different molar ratios of Mn/Ce(6:1,10:1,15:1)were investigated for the low-temperature selective catalytic reduction(SCR)of NO_x with NH_3.The synthesized catalysts were characterized by HRTEM,SEM,XRD,BET,XPS,and NH_3-TPD technologies.The characterization results indicated that manganese and cerium oxide particles dispersed on the surface of the TiO_2–NG support uniformly,and that manganese and cerium oxides existed in different valences on the surface of the TiO_2–NG support.At Mn element loading of 8 wt%,MnO_x–CeO_2(10:1)/TiO_2–1%NG displayed superior activity and improved SO_(2 )resistance.On the basis of the catalyst characterization,excellent catalytic performance and SO_2 tolerance at low temperature were attributed to the high content of manganese with high oxidation valence,extensive oxidation of NO into NO_2 by CeO_2 and strong NO adsorption capacity,and electron transfer of N-doped graphene. | Chunlin ZHAO Yanxia WU Hailong LIANG Xi CHEN Jie TANG Xianzhong WANG | 2018 | Journal of Advanced Ceramics2018，7，3： | 5 |
| 14 | Mixed lineage kinase domain-like protein induces RGC-5 necroptosis following elevated hydrostatic pressure显示文摘 | Lvshuang Liao Lei Shang Na Li Shuchao Wang Mi Wang Yanxia Huang Dan Chen Jufang Huang Kun Xiong | 2017 | Acta Biochimica et Biophysica Sinica2017，49，10： | 5 |
| 15 | Evaluation of oasis stability in the lower reaches of the Tarim River显示文摘Oasis stability in the lower reaches of the Tarim River was assessed at the landscape scale(including changes in landscape pattern and land use in the oasis) and at the regional scale(including the cold-island effect and NDVI of the oasis) based on the methods of landscape ecology,GIS and Remote Sensing(RS).Thematic Mapping(TM) remote sensing images from 1990,2000 and 2009 were employed along with the related meteorological and hydrological data pertaining to the reclamation area of the oasis in the lower reaches of the Tarim River.The results indicated that landscape heterogeneity and oasis complexity increased between 1990 and 2000.The comprehensive index of the degree of land use,the average index of the cold-island effect,NDVI value and oasis stability all decreased.However,the change trends in the indices referred to above were opposite between 2000 and 2009,and oasis stability was enhanced to some extent. | Chao LENG YaNing CHEN XinGong LI YanXia SUN | 2011 | Journal of Arid Land2011，3，2： | 4 |
| 16 | Comparative evaluation of the impact of GRAPES and MM5 meteorology on CMAQ prediction over Pearl River Delta, China显示文摘The community multiscale air quality (CMAQ) model was used to forecast air quality over the Pearl River Delta region from December 2013 to January 2014.The pollution forecasting performance of CMAQ coupled with two different meteorological models,i.e.,the global/regional assimilation and prediction system (GRAPES) and the fifth-generation mesoscale model (MM5),was assessed by comparison with observational data.The effects of meteorological factors and physicochemical processes on the forecast results were discussed through process analysis.The results showed that both models exhibited good performance but that of GRAPES-CMAQ was better.GRAPES was superior in predicting the overall variation tendencies of meteorological fields,but it showed large deviations in atmospheric pressure and wind speed.This contributed to the higher correlation coefficients of the pollutants with GRAPES-CMAQ but with greater deviations.The underestimations of nitrate and ammonium salt contributed to the underestimations of both particulate matter and extinction coefficients.Source emissions made the only positive contributions to surface layer SO2,CO,and NO.It was found that O3 originated primarily from horizontal and vertical transport and that its consumption was predominantly via chemical processes.Conversely,NO2 was found derived primarily from chemical production. | Tao Deng Yiang Chen Qilin Wan Yanxia Zhang Xuejiao Deng Yanyan Huang Guangfeng Dai Fei Li | 2018 | Particuology2018，16，5： | 4 |
| 17 | Application of regional citrate anticoagulation in patients at high risk of bleeding during intermittent hemodialysis:a prospective multicenter randomized controlled trial显示文摘Objective:Safe and effective anticoagulation is essential for hemodialysis patients who are at high risk of bleeding.The purpose of this trial is to evaluate the effectiveness and safety of two-stage regional citrate anticoagulation(RCA)combined with sequential anticoagulation and standard calcium-containing dialysate in intermittent hemodialysis(IHD)treatment.Methods:Patients at high risk of bleeding who underwent IHD from September 2019 to May 2021 were prospectively enrolled in 13 blood purification centers of nephrology departments,and were randomly divided into RCA group and saline flushing group.In the RCA group,0.04 g/mL sodium citrate was infused from the start of the dialysis line during blood draining and at the venous expansion chamber.The sodium citrate was stopped after 3 h of dialysis,which was changed to sequential dialysis without anticoagulant.The hazard ratios for coagulation were according to baseline.Results:A total of 159 patients and 208 sessions were enrolled,including RCA group(80 patients,110 sessions)and saline flushing group(79 patients,98 sessions).The incidence of severe coagulation events of extracorporeal circulation in the RCA group was significantly lower than that in the saline flushing group(3.64%vs.20.41%,P<0.001).The survival time of the filter pipeline in the RCA group was significantly longer than that in the saline flushing group((238.34±9.33)min vs.(221.73±34.10)min,P<0.001).The urea clearance index(Kt/V)in the RCA group was similar to that in the saline flushing group with no statistically significant difference(1.12±0.34 vs.1.08±0.34,P=0.41).Conclusions:Compared with saline flushing,the two-stage RCA combined with a sequential anticoagulation strategy significantly reduced extracorporeal circulation clotting events and prolonged the dialysis time without serious adverse events. | Xiaoyan TANG Dezheng CHEN Ling ZHANG Ping FU Yanxia CHEN Zhou XIAO Xiangcheng XIAO Weisheng PENG Li CHENG Yanmin ZHANG Hongbo LI Kehui LI Bizhen GOU Xin WU Qian YU Lijun JIAN Zaizhi ZHU Yu WEN Cheng LIU Hen XUE Hongyu ZHANG Xin HE Bin YAN Liping ZHONG Bin HUANG Mingying MAO | 2022 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2022，23，11： | 4 |
| 18 | Insight into the interaction between Ni-rich LiNi0.8Co0.1Mn0.1O2 cathode and BF4--introducing electrolyte at 4.5V high voltage显示文摘Owing to the high specific capacity and high voltage,Ni-rich(LiNi0.8Co0.1Mn0.1O2,LNCM811)cathode has been considered as one of the most promising candidate cathode materials for next generation lithium ion batteries,whereas severe capacity fading greatly hinders its practical application.Notably,the compatibility of Ni-rich materials with LiBF4-containing electrolyte has not yet been realized.Herein,1 M LiPF6-based electrolyte with introducing 2 M LiBF4 is proposed to dramatically improve the cyclic stability of high voltage LNCM811/Li half-cell.Addition of high concentrated LiBF4 improves the moisture stability of electrolyte,which hinders the generation of harmful by-product HF,resulting in improved interfacial stability of LNCM811.Lithium plating/stripping reaction of Li/Li symmetric cell confirms that the enhanced cyclic stability is ascribed to the improved interfacial stability of LNCM811 instead of lithium electrode.Morphology and composition characterization results reveal that LiBF4 participates in the CEI film-forming reaction,resulting in suppressed oxidation of electrolyte and interfacial structural destruction of LNCM811. | Guangyuan Lan Hebing Zhou Lidan Xing Jiawei Chen Zifei Li Rude Guo Yanxia Che Weishan Li | 2019 | Journal of Energy Chemistry2019，28，12： | 3 |
| 19 | Dual-function antibacterial surfaces to resist and kill bacteria:Painting a picture with two brushes simultaneously显示文摘Attachment of bacteria and subsequent formation of biofilms on material surfaces lead to serious consequences including infection,contamination and biofouling,posing a prominent threat to human health and causing problems in many industries.Therefore,it is highly desirable to endow the surfaces with antibacterial properties.Traditional antibacterial surfaces are designed via either bacteria-resisting strategy to prevent the initial adhesion of bacteria or bacteria-killing strategy to eradicate any bacteria that attach to the surface.However,these single-function surfaces have their inherent shortcomings and cannot realize long-term efficacy against bacteria.In recent years,various dual-function antibacterial surfaces with both bacteria-resisting and bacteria-killing properties together have been developed,showing better performance for combating surface-attached bacteria and preventing formation of biofilms.In this review,we summarize the recent development of these dual-function antibacterial surfaces.We focus on the design principles and fabrication strategies of such surfaces and highlight the representative examples,which are categorized specifically into two types according to the anti-adhesive and bactericidal properties are simultaneous or switchable.A brief perspective is finally presented on current challenges and future research directions. | Yi Zou Yanxia Zhang Qian Yu Hong Chen | 2021 | Journal of Materials Science & Technology2021，，11： | 3 |
| 20 | Studies of the first lithiation of graphite materials by electrochemical impedance spectroscopy显示文摘First lithiation of graphite electrode in 1 mol/L LiPF6-EC:DEC:DMC electrolyte was investi- gated by electrochemical impedance spectroscopy (EIS). The results illustrated that the first arc in the high-frequency range observed in the Nyquist dia- gram appears near 0.9 V in the initial lithiation of graphite electrode, and its diameter increases with the decrease of polarization potential. These EIS features were attributed to the formation and growth of SEI film. Appropriate equivalent circuit was pro- posed to fit the experimental EIS data. The fitting results revealed the process of the formation and growth of SEI film, and evaluated quantitatively the resistance of charge transfer, as well as the capaci- tance of double layer along with the increase of po- larization potentials. | ZHUANG Quanchao CHEN Zuofeng DONG Quanfeng JIANG Yanxia HUANG Ling SUN Shigang | 2006 | Chinese Science Bulletin2006，51，9： | 3 |
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