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| 1 | 儿童功能性胃肠病罗马Ⅳ标准显示文摘罗马标准是目前关于功能性胃肠病( FGID)分类最全面且不断更新的标准。罗马Ⅰ、Ⅱ标准分别于1994年、1999年发布。罗马Ⅱ标准开始单列儿童FGID分类。2006年,根据年龄不同,婴幼儿(0-36个月)和儿童(〉36个月) FGID的罗马Ⅲ诊断标准发布,但相关的流行病学、病理生理学、诊断检查、治疗策略以及预后等资料都很少。 | Marc A. Benninga Samuel Nurko Christophe Faure Paul E. Hyman Ian St. James Roberts Neil L. Schechter Jeffrey S. Hyams Carlo Di Lorenzo Miguel Saps Robert J. Shulman Annamaria Staiano Miranda van Tilburg | 2017 | 中华儿科杂志2017，55，1： | 108 |
| 2 | 缺血性卒中的一级预防——美国心脏协会/美国卒中协会卒中委员会指南 动脉粥样硬化性周围血管病跨学科工作组、心血管护理委员会、临床心脏病学委员会、营养、体力活动和代谢委员会以及医疗质量和转归研究跨学科工作组共同倡导显示文摘背景和目的本指南提供有关各种确定和潜在的卒中危险因素证据的概述,并提供降低卒中风险的推荐。方法写作组成员由委员会主席根据每位作者先前在相关课题领域中的工作提名,并经美国心脏协会(AHA)卒中委员会科学声明监督委员会批准。写作组采用系统文献回顾(涵盖时间段为2001年最后一次回顾发表到2005年1月),参考先前已发表的指南、个人文件和专家意见来概括现有的证据,指明现有知识的差距;如果合适,则根据标准的AHA标准做出简明的推荐。写作组全体成员在撰写过程中均有很多机会对推荐进行评论并认可这份声明的最终版本。在AHA科学咨询与协调委员会批准之前,本指南已进行过广泛的同行评议。结果对评价个体首次卒中风险的流程图进行评估。根据干预的可能性(不可干预、可干预或潜在可干预)和证据的强度(证据充分或证据不太充分),对首次卒中的危险因素或风险标记物进行分类。不可干预的危险因素包括年龄、性别、出生体重低、人种/种族和遗传因素。证据充分的可干预危险因素包括高血压、主动或被动吸烟、糖尿病、心房颤动和某些其他心脏病、血脂异常、颈动脉狭窄、镰状细胞病、绝经后激素治疗、不良饮食习惯、缺乏体力活动、肥胖和体脂分布。证据不太充分或潜在的可干预危险因素包括代谢综合征、酗酒、药物滥用、口服避孕药、睡眠呼吸障碍、偏头痛、高同型半胱氨酸血症、脂蛋白(a)升高、脂蛋白相关的磷脂酶升高、高凝状态、炎症和感染。对应用阿司匹林进行卒中一级预防的资料进行回顾。结论有大量证据可以用于确定增加首次卒中风险的各种特殊因素和提供降低这种风险的策略。 | Larry B. Goldstein Robert Adams Mark J. Alberts Lawrence J. Appel Lawrence M. Brass Cheryl D. Bushnell Antonio Culebras Thomas J. DeGraba Philip B. Gorelick John R. Guyton Robert G. Hart George Howard Margaret Kelly-Hayes J.V. (Ian) Nixon Ralph L. Sacco 苏克江 高宗恩 | 2006 | 国际脑血管病杂志2006，14，8： | 28 |
| 3 | 卒中一级预防指南 美国心脏协会/美国卒中协会为医疗卫生专业人员制定的指南美国神经病学学会肯定本指南作为神经科医生继续教育工具的价值显示文摘背景和目的本指南对各种已确定和新出现的卒中危险因素的证据进行概述,以提供降低首次卒中风险的循证推荐。方法写作组成员由委员会主席根据每位成员先前在相关课题领域中的工作提名,并经美国心脏协会(American HeartAssociation,AHA)卒中委员会科学声明监督委员会批准。写作组采用系统文献回顾的方法(涵盖时间为2006年上一次回顾发表到2009年4月),参考先前已发表的指南、个人文件和专家意见来总结现有证据,并指出现有知识的差距;如果合适,则根据标准的AHA标准做出推荐。写作组全体成员均有机会对推荐进行评论并审核这份声明的最终文本。在AHA科学咨询和协调委员会考察和批准之前,本指南已南卒中委员会领导层和AIIA科学声明督察委员会进行过广泛的同行评议。结果对评价个体首次卒巾风险的流程图进行了评价。根据干预的町能性(不可于预、可于预或潜在可干预)和证据的强度(证据充分或证据不太充分),对首次卒中的危险因素或风险标记物进行分类。不可干预危险因素包括年龄、性别、低出生体质量、人种/种族和遗传倾向。证据充分的叮干预危险因素包括高血压、吸烟、糖尿病、心房颤动和某些其他心脏病、血脂异常、颈动脉狭窄、镰状细胞病、绝经后激素治疗、不良饮食习惯、体力活动过少以及肥胖和体脂分布。证据不太充分或潜在的可干预危险因素包括代谢综合征、酗酒、药物滥用、口服避孕药、睡眠呼吸障碍、偏头痛、高同型半胱氨酸血症、脂蛋白(a)升高、高凝状态、炎症和感染。对用阿司匹林进行卒中一级预防的资料进行了回顾。结论多方面的证据可用于确定能增高首次卒中风险的多种具体因素并提供降低这种风险的策略。 | Larry B. Goldstein Cheryl D. Bushnell Robert J. Adams Lawrence J. Appel Lynne T. Braun Seemant Chaturvedi Mark A. Creager Antonio Culebras Robert H. Eckel Robert G. Hart Judith A. Hinchey Virginia J. Howard Edward C. Jauch Steven R. Levine James F. Meschia Wesley S. Moore J.V. (Ian) Nixon Thomas A. Pearson 张霞(译) 尤寿江(译) 陈孝东(译) 卢涛声(译) 石际俊(译) 曹勇军(译) 徐兴顺(译) | 2010 | 国际脑血管病杂志2010，18，12： | 12 |
| 4 | Radiofrequency ablation for early oesophageal squamous neoplasia:Outcomes form United Kingdom registry显示文摘AIM:To report outcomes on patients undergoing radiofrequency ablation(RFA)for early oesophageal squamous neoplasia from a National Registry.METHODS:A Prospective cohort study from 8 tertiary referral centres in the United Kingdom.Patients with squamous high grade dysplasia(HGD)and early squamous cell carcinoma(ESCC)confined to the mucosa were treated.Visible lesions were removed by endoscopic mucosal resection(EMR)before RFA.Following initial RFA treatment,patients were followed up 3monthly.Residual flat dysplasia was treated with RFA until complete reversal dysplasia(CR-D)was achieved or progression to invasive Squamous cell cancer defined as infiltration into the submucosa layer or beyond.The main outcome measures were CR-D at 12 mo from start of treatment,long term durability,progression to cancer and adverse events.RESULTS:Twenty patients with squamous HGD/ESCC completed treatment protocol.Five patients(25%)had EMR before starting RFA treatment.CR-D was 50%at12 mo with a median of 1 RFA treatment,mean 1.5(range 1-3).Two further patients achieved CR-D with repeat RFA after this time.Eighty per cent with CR-D remain dysplasia free at latest biopsy,with median follow up 24 mo(IQR 17-54).Six of 20 patients(30%)progressed to invasive cancer at 1 year.Four patients(20%)required endoscopic dilatations for symptomatic structuring after treatment.Two of these patients have required serial dilatations thereafter for symptomatic dysphagia with a median of 4 dilatations per patient.The other 2 patients required only a single dilatation to achieve an adequate symptomatic response.One patient developed cancer during follow up after end of treatment protocol.CONCLUSION:The role of RFA in these patients re-mains unclear.In our series 50%patients responded at12 mo.These figures are lower than limited published data. | Rehan J Haidry Mohammed A Butt Jason Dunn Matthew Banks Abhinav Gupta Howard Smart Pradeep Bhandari Lesley Ann Smith Robert Willert Grant Fullarton Morris John Massimo Di Pietro Ian Penman Marco Novelli Laurence B Lovat | 2013 | World Journal of Gastroenterology2013，19，36： | 7 |
| 5 | Multidisciplinary management of nonfunctional neuroendocrine tumor of the pancreas显示文摘Pancreatic neuroendocrine tumors(PNETs) are a rare and diverse group of tumors; nonfunctional(NF) PNETs account for the majority of cases. Most patients with NF-PNETs have metastatic disease at the time of presentation. A variety of treatment modalities exist, including medical, liver directed, and surgical treatments. Aggressive surgical management is associated with prolonged survival, however available data are limited by selection bias and the frequent combination of PNETs with carcinoid tumors. Although few patients with metastatic disease will be cured, application of currently available therapies in a multidisciplinary setting can lead to excellent outcomes with prolonged patient survival. | Ian W Folkert Paul Hernandez Robert E Roses | 2016 | World Journal of Gastroenterology2016，22，11： | 6 |
| 6 | Use of infliximab in the prevention and delay of colectomy in severe steroid dependant and refractory ulcerative colitis显示文摘AIM: To determine if infliximab can prevent or delay surgery in refractory ulcerative colitis (UC). METHODS: UC patients who failed to have their disease controlled with conventional therapies and were to undergo colectomy if infliximab failed to induce a clinical improvement were reviewed. Patients were primarily treated with a single 5 mg/kg infliximab dose. The Colitis Activity Index (CAI) was used to determine response and remission. Data of 8 wk response and colectomy rates at 6 mo and 12 mo were collected. RESULTS: Fifteen patients were included, 7 with UC unresponsive or intolerant to Ⅳ hydrocortisone, and 8 with active disease despite oral steroids (all but one with therapeutic dosage and duration of immunomodulation). All the Ⅳ hydrocortisone-resistant/intolerant patients had been on azathioprine/6-MP < 8 wk. At 8 wk, infliximab induced a response in 86.7% (13/15) with 40% in remission (6/15). Within 6 mo of treatment 26.7% (4/15) had undergone colectomy and surgery was avoided in 46.6% (7/15) at 12 mo. The colectomy rate at 12 mo in those on immunomodulatory therapy < 8 wk at time of infliximab was 12.5% (1/8) compared with 100% (7/7) in patients who were on long-term maintenance immunomodulators (P < 0.02). CONCLUSION: Infliximab prevented colectomy due to active disease in immunomodulatory-na?ve, refractory UC patients comparable to the use of Cyclosporine. In patients, however, on effective dosage and duration of immunomodulation at time of infliximab therapy colectomy was not avoided. | Robert P Willert Ian Craig Lawrance | 2008 | World Journal of Gastroenterology2008，14，16： | 5 |
| 7 | Living vs. deceased donor liver transplantation for hepatocellular carcinoma: a systematic review and meta‐analysis显示文摘 | Robert C. Grant Lakhbir Sandhu Peter R. Dixon Paul D. Greig David R. Grant Ian D. McGilvray | 2012 | Clin Transplant2012，，1： | 4 |
| 8 | Primary phacoemulsification for uncontrolled angle-closure glaucoma 1 1 None of the authors has a financial or proprietary interest in any material or method mentioned.显示文摘 | Timothy V Roberts Ian C Francis Sam Lertusumitkul Medduma B Kappagoda Minas T Coroneo | 2000 | Journal of Cataract & Refractive Surgery2000，，7： | 3 |
| 9 | 对动物实验进行系统评价的必要性(英文)显示文摘 | Pandora Pound Ian Roberts 黄进 杜亮 | 2005 | 中国循证医学杂志2005，5，1： | 3 |
| 10 | 人工合成松乳菇菌根及杂菌侵染宿主的形态学观察和分子鉴定显示文摘将松乳菇(Lactarius deliciosus)菌丝块人工接种于意大利石松(Pinus pinea)、辐射松(P.radiata)、华山松(P.armandii)3种宿主植物的幼苗根部合成外生菌根,结果表明:松乳菇与意大利石松、辐射松、华山松均可形成外生菌根,菌根呈二叉状分支,分支末端呈棒状,整体呈鲜黄色至橘黄色。在合成松乳菇菌根过程中发现,杂菌1号可与意大利石松形成外生菌根,菌根呈二叉状分支,分支端细长,呈冠状膨大,菌套表面菌丝呈卷毛状,赭色至黄棕色,颜色随着时间变深棕色;杂菌2号可与华山松形成外生菌根,菌根呈二叉状分支,末端呈球状,浅黄色且半透明状。经ITS序列鉴定杂菌1号为Sphaerosporella sp.,杂菌2号为Peziza ostracoderma。 | 王迪 HALL Ian Robert 何晓兰 熊卫萍 彭卫红 | 2021 | 食用菌学报2021，28，3： | 3 |
| 11 | 国际化妆品监管合作组织特别工作组关于个人护理产品中纳米技术应用的报告显示文摘1引言
国际化妆品监管合作组织(ICCR)是由美国、日本、欧盟和加拿大的化妆品政府监管主管部门组建的。这个多边框架组织的宗旨是在尽量减少国际贸易障碍的同时,给予全球消费者最高水平的保护。 | Jay Ansell Robert Bronaugh Luisa K.Carter Qasim Chaudhry Mark Lafranconi Tetsuji Nishimura Florian Schellauf Homer Swei Ian Tooley 姜宜凡 | 2011 | 香料香精化妆品2011，，1： | 3 |
| 12 | Thermally evaporated thin films of SnS for application in solar cell devices显示文摘 | Robert W. Miles Ogah E. Ogah Guillaume Zoppi Ian Forbes | 2009 | Thin Solid Films2009，，17： | 2 |
| 13 | Different types of small nerve fibers in eutopic endometrium and myometrium in women with endometriosis显示文摘 | Natsuko Tokushige Robert Markham Peter Russell Ian S. Fraser | 2007 | Fertility and Sterility2007，，4： | 2 |
| 14 | The study of aluminium anodes for high power density Al/air batteries with brine electrolytes显示文摘 | Maria Nestoridi Derek Pletcher Robert J.K. Wood Shuncai Wang Richard L. Jones Keith R. Stokes Ian Wilcock | 2008 | Journal of Power Sources2008，，1： | 2 |
| 15 | Effect of Cardiac Resynchronization on Myocardial Efficiency and Regional Oxidative Metabolism显示文摘 | Heikki Ukkonen Rob S.B. Beanlands Ian G. Burwash Robert A. de Kemp Claude Nahmias Ernest Fallen Michael R.S. Hill Anthony S.L. Tang | 2003 | Circulation: Journal of the American Heart Association2003，，1： | 2 |
| 16 | EMR for Barrett’s esophagus–related superficial neoplasms offers better diagnostic reproducibility than mucosal biopsy 显示文摘 | Mari Mino-Kenudson Mindy J. Hull Ian Brown Alona Muzikansky Amitabh Srivastava Jonathan Glickman Do-Youn Park Lawrence Zuckerberg Joseph Misdraji Robert D. Odze Gregory Y. Lauwers | 2007 | Gastrointestinal Endoscopy2007，，： | 2 |
| 17 | The Pressor Effect of Moderate Alcohol Consumption in Man: A Search for Mechanisms显示文摘 | PETER D. ARKWRIGHT LAWRENCE J. BEILIN ROBERT VANDONGEN IAN A. ROUSE CLAIRE LALOR | 1982 | Circulation1982，，3： | 2 |
| 18 | Threshold Chloride Concentrations and Passivity Breakdown of Rebar Steel in Real Concrete Solution at Different pH Conditions with the Addition of Glycerol显示文摘Addition of glycerol as a viscosity modifier in concrete is proposed to decrease the permeability of corrosioninducing ions such as chloride and sulfate.In addition to controlling the permeabiUty of concrete,glycerol could perform as an inhibitor of corrosion of rebar steel.Cyclic polarization studies were carried out on metallographically polished rebar steel specimens in actual concrete solutions at two different pH conditions(pH 12.5 and 9.0) and different chloride concentrations.The threshold concentration of chloride for passivity breakdown at pH 12.5 was greater than50 × 10^(-3) mol/L in the absence of glycerol addition.The threshold increased to 81 × 10^(-3)mol/L upon addition of 2 wt%glycerol.The threshold chloride concentration for passivity breakdown in pH 9.0 cement solution was 0.2 × 10^(-3) mol/L without glycerol addition.No beneficial effect of glycerol was observed in the low pH condition.However,glycerol enhanced the passivation kinetics of the rebar steel in saturated cement solution,but did not affect the electronic properties of the passive layer.The passive layers exhibited n-type semiconductivity with a charge carrier density in the range of2-7.5× 10^(20) cm^(-3).Polarization of the specimens to potentials is higher than oxygen evolution potential,resulted in transition top-type semiconducting character due to an accumulation of holes.This phenomenon could be related to the passivity breakdown. | Robert Blair Batric Pesic Jacob Kline Ian Ehrsam Krishnan Raja | 2017 | Acta Metallurgica Sinica(English Letters)2017，30，4： | 2 |
| 19 | 导致成人多囊肾血尿的原因显示文摘 | Robert Dedi Sunil Bhandari John H Turney Aleck M Brownjohn Ian EardLey 李寒 | 2002 | 英国医学杂志中文版2002，5，3： | 2 |
| 20 | An adult Xp11.2 translocation renal carcinoma showing response to treatment with sunitinib显示文摘 | Thinn P. Pwint Valentine Macaulay Ian S.D. Roberts Mark Sullivan Andrew Protheroe | 2011 | Urologic Oncology: Seminars and Original Investigations2011，，6： | 2 |
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