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| 1 | Preliminary Scientific Results of Chang'E-1 Lunar Orbiter:Based on Payloads Detection Data in the First Phase显示文摘Chang'E-1 lunar Orbiter was launched by Long March 3A rocket from Xichang Satel-lite Launch Center at 18:05BT(Beijing Time) Oct.24,2007.It is the first step of its ambitious three-stage moon program,a new milestone in the Chinese space exploration history.The primary science objectives of Chang'E-1 lunar orbiter are to obtain three-Dimension(3D) stereo images of the lunar surface,to analyze the distribution and abundance of elements on the surface,to investigate the thickness of lunar soil,evaluate helium-3 resources and other characteristics,and to detect the space environment around the moon.To achieve the above four mission objectives,eight sets of scientific instruments are chosen as the payloads of the lunar orbiter,including a CCD stereo camera(CCD),a Sagnac-based interferometer spectrometer(ⅡM),a Laser Altimeter(LAM),a Microwave Radiometer(MRM),a Gamma-Ray Spectrometer(GRS),an X-ray spectrometer(XRS),a High-Energy Particle Detector(HPD),and two Solar Wind Ion Detectors(SWID).The detected data of the payloads show that all payloads work well.This paper introduces the status of payloads in the first phase and preliminary scientific results. | OUYANG Ziyuan JIANG Jingshan LI Chunlai SUN Huixian ZOU Yongliao LIU Jianzhong LIU Jianjun ZHAO Baochang REN Xin YANG Jianfeng ZHANG Wenxi WANG Jianyu MOU Lingli CHANG Jin ZHANG Liyan WANG Huanyu LI Yongquan ZHANG Xiaohui ZHENG Yongchun WANG Shijin BIAN Wei | 2008 | 空间科学学报2008，28，5： | 24 |
| 2 | Cardiotoxicity of 5-fluorouracil and capecitabine in Chinese patients: a prospective study显示文摘Background:5-Fluorouracil(5-FU)and capecitabine-associated cardiotoxicity ranging from asymptomatic electro-cardiography(ECG)abnormalities to severe myocardial infarction has been reported in a number of studies,but such cardiotoxicity in Chinese patients with malignant diseases has not been investigated to date.In the present study,we aimed to prospectively evaluate the incidence rates and clinical manifestations of 5-FU-and capecitabine-associated cardiotoxicity in cancer patients recruited from multiple centers in China.Methods:Among the 527 patients who completed the study,196 received 5-FU-based chemotherapy and 331 received capecitabine-based chemotherapy as either first-line or adjuvant therapy.Adverse events were reported during the treatment and up to 28 days of follow-up.Outcome measures included ECG,myocardial enzymes,cardiac troponin,brain natriuretic peptide and echocardiography.Univariate analysis and logistic regression were performed for subgroup analysis and identification of significant independent variables that are associated with cardiotoxicity of both agents.Results:In total,161 of 527 patients(30.6%)experienced cardiotoxicity.The incidence rate of cardiotoxicity was 33.8%(112/331)in the capecitabine group,which was significantly higher than the rate of 25%(49/196)in the 5-FU group(P=0.0042).110/527 patients(20.9%)suffered arrhythmia,105/527(19.9%)developed ischemic changes,while only 20/527 patients(3.8%)presented heart failure and 6/527 patients(1.1%)had myocardial infarction.Pre-existing cardiac disease,hypertension,capecitabine-based chemotherapy and duration of treatment were identified as sig-nificant risk factors associated with cardiotoxicity.The odds ratio were 15.7(prior history of cardiac disease versus no history),1.86(capecitabine versus 5-FU),1.06(5-8 versus 1-4 chemotherapy cycles)and 1.58(hypertension versus no hypertension),respectively.Conclusions:Cardiotoxicity induced by fluoropyrimidines in the Chinese population may be underestimated in clini-cal practice.Close monitoring of patients is recommended,especially for those patients at high risk for cardiotoxicity.Possible risk factors are duration of treatment,capecitabine-based chemotherapy,pre-existing cardiac diseases and hypertension.Trial registration This study was initiated on January 22,2014 and has been retrospectively registered with the registra-tion number ChiCTR1800015434 . | Jianjun Peng Chao Dong Chang Wang Weihua Li Hao Yu Min Zhang Qun Zhao Bo Zhu Jun Zhang Wenliang Li Fenghua Wang Qiong Wu Wenhao Zhou Ying Yuan Meng Qiu Gong Chen | 2018 | Cancer Communications2018，38，1： | 23 |
| 3 | De novo mutation in ATP6V1B2 impairs lysosome acidification and causes dominant deafness-onychodystrophy syndrome显示文摘 | Yongyi Yuan Jianguo Zhang Qing Chang Jin Zeng Feng Xin Jianjun Wang Qingyan Zhu Jing Wu Jingqiao Lu Weiwei Guo Xukun Yan Hui Jiang Binfei Zhou Qi Li Xue Gao Huijun Yuan Shiming Yang Dongyi Han Zixu Mao Ping Chen Xi Lin Pu Dai | 2014 | Cell Research2014，24，11： | 13 |
| 4 | Chang'E-1 Lunar Mission:An Overview and Primary Science Results显示文摘Chang'E-1 is the first lunar mission in China,which was successfully launched on Oct.24th,2007.It was guided to crash on the Moon on March 1,2009,at 52.36°E,1.50°S,in the north of Mare Fecunditatis.The total mission lasted 495 days,exceeding the designed life-span about four months.1.37Terabytes raw data was received from Chang'E-1.It was then processed into 4Terabytes science data at different levels.A series of science results have been achieved by analyzing and applicating these data,especially 'global image of the Moon of China's first lunar exploration mission'.Four scientific goals of Chang'E-1 have been achieved.It provides abundant materials for the research of lunar sciences and cosmochemistry.Meanwhile these results will serve for China's future lunar missions. | Ouyang Ziyuan Li Chunlai Lu Chang Liu Jianzhong Zou Yongliao Zhang Hongbo Jianjun Zuo Wei Su Yah Wen Weibin Bian Wei Zhao Baochang Wang Jianyu Yang Jianfeng Chang Jin Wang Huanyu Zhang Xiaohui Wang Shijin Wang Min Ren Xin Mu Lingli Kong Deqing Wang Xiaoqian Wang Fang Geng Liang Zhang Zhoubin Zheng Lei Zhu Xinying Zheng Yongchun Li Junduo Zou Xiaoduan Xu Chun Shi Shuobiao Gao Yifei Gao Guannan | 2010 | 空间科学学报2010，30，5： | 11 |
| 5 | Vertically aligned reduced graphene oxide/Ti_(3)C_(2)T_(x)MXene hybrid hydrogel for highly efficient solar steam generation显示文摘Effective utilization of abundant solar energy for desalination of seawater and purification of wastewater is one of sustainable techniques for production of clean water,helping relieve global water resource shortage.Herein,we fabricate a vertically aligned reduced graphene oxide/Ti_(3)C_(2)T_(x)MXene(A-RGO/MX)hybrid hydrogel with aligned channels as an independent solar steam generation device for highly efficient solar steam generation.The vertically aligned channels,generated by a liquid nitrogen-assisted directional-freezing process,not only rapidly transport water upward to the evaporation surface for efficient solar steam generation,but also facilitate multiple reflections of solar light inside the channels for efficient solar light absorption.The deliberate slight reduction endows the RGO with plenty of polar groups,decreasing the water vaporization enthalpy effectively and hence accelerating water evaporation efficiently.The MXene sheets,infiltrated inside the A-RGO hydrogel on the basis of Marangoni effect,enhance light absorption capacity and photothermal conversion performance.As a result,the A-RGO/MX hybrid hydrogel achieves a water evaporation rate of 2.09 kg·m^(−2)·h^(−1)with a high conversion efficiency of 93.5%under 1-sun irradiation.Additionally,this photothermal conversion hydrogel rapidly desalinates seawater and purifies wastewater to generate clean water with outstanding ion rejection rates of above 99%for most ions. | Wei Li Xiaofeng Li Wei Chang Jing Wu Pengfei Liu Jianjun Wang Xi Yao Zhong-Zhen Yu | 2020 | Nano Research2020，13，11： | 10 |
| 6 | Reconstruction of nerve root sheaths for sacral extradural spinal meningeal cysts with spinal nerve root fibers显示文摘This study analyzed the clinical characteristics and outcomes of sacral extradural spinal meningeal cysts with spinal nerve root fibers treated by reconstruction of the nerve root sheaths.The relationships between the cysts and spinal nerve root fibers were examined microscopically,the cysts were partially excised,and the defects were oversewn to reconstruct the nerve root sheaths.The Improved Japanese Orthopedic Association(IJOA)scoring system was used to evaluate preoperative and postoperative neurological function.Thirty-eight patients were included in this study,with a mean age of 41.4±15.57 years.The mean IJOA score was 18.8±1.32 preoperatively and 19.6±0.65 postoperatively,which was a significant difference(t=–3.77,P=0.001).These results indicate a significant improvement in neurological function after surgery.The most significant improvement in neurological function was sensation(z=–2.86,P=0.004),followed by bowel/bladder function(z=–2.31,P=0.02). | SUN JianJun WANG ZhenYu LI ZhenDong WU HaiBo YEN RuYu ZHENG Mei CHANG Qing LIU Isabelle Yisha | 2013 | Science China(Life Sciences)2013，56，11： | 8 |
| 7 | Data Analysis of Chang'E-1 Gamma-Ray Spectrometer and Global Distribution of U,K,and Th Elemental Abundances显示文摘Gamma 光线分光计(GRS ) 是 Chang'E-1 (CE-1 ) 上的主要收费载重之一月亮的探查,主要试图在月亮的表面上检测元素的丰富和分布。在 03:58 在 2007 年 11 月 28 日,它执行了月亮的 gamma 光线的第一观察。2008 年 10 月 24 日,有效 gamma 光线系列的 2105 h 被 CE-1 GRS 获得了,它盖住月亮的整个表面。这份报纸主要描述处理由使用导出元素的丰富的过程和 CE-1 GRS 时间系列改正了系列的方法的数据:首先,到进为印射的象素的箱数据;然后,执行累积系列的背景扣除并且获得元素的一个山峰区域;并且最后,当模特儿使用元素的丰富倒置生产元素的丰富。在这些上基于比 EPR 在 5s 处理方法, U 的全球丰富地图, K,和 Th。在在 near-EPR 海底山下面的岩浆结晶化压力和融化的条件之间的关联暗示来源吗? | ZOU Yongliao ZHANG Liyan LIU Jianzhong MU Lingli REN Xin ZHANG Guangliang CHANG Jin YAN Jun ZHANG Nan ZHANG Hongbo LU Chang LIU Jianjun ZUO Wei SU Yan WEN Weibin BIAN Wei WANG Min XU Chun LI Chunlai OUYANG Ziyuan | 2011 | Acta Geologica Sinica(English Edition)2011，85，6： | 6 |
| 8 | BKI1 Regulates Plant Architecture through Coordinated Inhibition of the Brassinosteroid and ERECTA Signaling Pathways in Arabidopsis显示文摘几百次充满白氨酸的重复像受体的 kinases (LRR-RLKs ) 玩在大量植物的不可缺少的角色发展、生理的过程。在基础、不活跃的地位控制 LRR-RLKs 的机制必要却很少学习。BKI1 是唯一的在 Arabidopsis 报导了受体 kinases 的禁止者,它否定地在 brassinosteroid 小径调整 BRI1。在这研究,我们发现 BKI1 能也与另一重要 LRR-RLK 交往, ERECTA (嗯) 。Phenotypic 分析显示出那 BKI1,包括花梗取向并且嗯一起调整植物建筑学,它是最新报导的显型在调停 BR 并且嗯调停发展进程。基因表示分析表明 BKI1 调整嗯应答的基因的一个子集。Kinase 试金证明 BKI1 禁止嗯 kinase 活动。另外, BKI1 抑制在上的版本嗯发信号主要依靠 BRI1 激活。我们的数据提供重要卓见进 RLK 的规定和激活并且建议 BKI1 作为 BRI1 的普通 suppressor 工作并且嗯发信号的小径。 | Dongxu Wang Cangjing Yang Haijiao Wang Zhihua Wu Jianjun Jiang Jingjing Liu Zhuona He Fang Chang Hong Ma Xuelu Wang | 2017 | Molecular Plant2017，10，2： | 5 |
| 9 | Progress of Jinping Underground laboratory for Nuclear Astrophysics(JUNA)显示文摘Jinping Underground laboratory for Nuclear Astrophysics(JUNA) will take the advantage of the ultra-low background of CJPL lab and high current accelerator based on an ECR source and a highly sensitive detector to directly study for the first time a number of crucial reactions occurring at their relevant stellar energies during the evolution of hydrostatic stars. In its first phase, JUNA aims at the direct measurements of^(25)Mg(p,γ)^(26)Al,^(19)F(p,α)^(16)O,^(13)C(α,n)^(16)O and ^(12)C(α,γ)^(16)O reactions. The experimental setup,which includes an accelerator system with high stability and high intensity, a detector system, and a shielding material with low background, will be established during the above research. The current progress of JUNA will be given. | WeiPing Liu ZhiHong Li JiangJun He XiaoDong Tang Gang Lian Zhu An JianJun Chang Han Chen QingHao Chen XiongJun Chen ZhiJun Chen BaoQun Cui XianChao Du ChangBo Fu Lin Gan Bing Guo GuoZhu He Alexander Heger SuQing Hou HanXiong Huang Ning Huang BaoLu Jia LiYang Jiang Shigeru Kubono JianMin Li KuoAng Li Tao Li YunJu Li Maria Lugaro XiaoBing Luo HongYi Ma ShaoBo Ma DongMing Mei YongZhong Qian JiuChang Qin Jie Ren YangPing Shen Jun Su LiangTing Sun WanPeng Tan Isao Tanihata Shuo Wang Peng Wang YouBao Wang Qi Wu ShiWei Xu ShengQuan Yan LiTao Yang Yao Yang XiangQing Yu Qian Yue Sheng Zeng HuanYu Zhang Hui Zhang LiYong Zhang NingTao Zhang QiWei Zhang Tao Zhang XiaoPeng Zhang XueZhen Zhang ZiMing Zhang Wei Zhao Zuo Zhao Chao Zhou | 2016 | Science China(Physics,Mechanics & Astronomy)2016，59，4： | 3 |
| 10 | Mechanical tests on the reconstructed anterior cruciate ligament fixed with allogenetic cortical bone cross-pin on the femoral side显示文摘 | Liu Chang Liu Yujie Zhang Yingze Qu Feng Li Shuyuan Wang Junliang Qi Wei Wang Aiyuan Wang Xin Liang Jianjun Liang Dongqi Zhu Juanli Liu Yang | 2014 | Chinese Medical Journal2014，，15： | 3 |
| 11 | Comparative analysis of significant wave height between a new Southern Ocean buoy and satellite altimeter显示文摘中国于2019年第35次南极考察中,首次在南大洋布放了锚系实时综合观测浮标(西风带海洋环境监测浮标,WEMB),为深入了解此海区的海洋环境变化提供了宝贵资料.国家海洋技术中心WEMB研究团队基于AVISO公开发布的多颗卫星高度计L3产品,通过数据配对,误差统计和最小二乘线性拟合等方法,对西风带海洋环境监测浮标的有效波高数据误差进行了分析与校正.校正后的浮标有效波高统计显示西风带常年处于大浪以上海况,观测期间内57%处于巨浪海况,并且伴随有高度相关的大风天气. | Jianjun Kang Runyu Mao Yiting Chang Hongli Fu | 2021 | Atmospheric and Oceanic Science Letters2021，14，5： | 3 |
| 12 | 5-氟尿嘧啶和卡培他滨对中国患者的心脏毒性:一项前瞻性研究显示文摘背景与目的已有许多研究报道5-氟尿嘧啶(5-Fluorouracil,5-FU)和卡培他滨相关的心脏毒性,严重程度从无症状心电图(electrocardiography,ECG)异常到严重心肌梗塞而不同。目前为止,对中国恶性肿瘤患者的这种心脏毒性尚无研究。本研究旨在前瞻性地对多个中心招募的癌症患者进行5-FU和卡培他滨相关心脏毒性的发生率和临床表现进行评估。方法在完成研究的527例患者中,196例接受基于5-FU的化疗,331例接受基于卡培他滨的化疗并以其为一线或辅助治疗。在治疗期间和长达28 d的随访期间对所发生的不良反应进行记录。疗效测量指标包括心电图、心肌酶、心肌肌钙蛋白、脑钠肽和超声心动图。使用单因素分析和logistic回归方法进行亚组分析和鉴定与两种药物的心脏毒性相关的显著性独立变量。结果 527例患者中有161例(30.6%)出现心脏毒性。卡培他滨组的心脏毒性发生率为33.8%(112/331),显著高于5-FU组25%(49/196)的发生率(P=0.0042)。110/527患者(20.9%)发生心律失常,105/527(19.9%)发生缺血性改变,而只有20/527患者(3.8%)出现心力衰竭,6/527患者(1.1%)出现心肌梗塞。既往的心脏病、高血压、卡培他滨为基础的化疗和治疗时间被确定为与心脏毒性相关的显著风险因素。优势比分别为15.7(心脏病史vs.无病史)、1.86(卡培他滨vs. 5-FU)、1.06(5–8个化疗周期vs. 1–4个化疗周期)和1.58(高血压vs.无高血压)。结论氟嘧啶类药物在中国人群中引起的心脏毒性可能在临床实践中被低估。建议密切监测患者,尤其是对心脏毒性高风险的患者。可能的风险因素包括治疗持续时间、基于卡培他滨的化疗、既往心脏病史和高血压史。 | Jianjun Peng Chao Dong Chang Wang Weihua Li Hao Yu Min Zhang Qun Zhao Bo Zhu Jun Zhang Wenliang Li Fenghua Wang Qiong Wu Wenhao Zhou Ying Yuan Meng Qiu Gong Chen | 2018 | 癌症2018，37，10： | 3 |
| 13 | Research on Dinoasur Footprints in Zizhou, Shaanxi Province, China显示文摘In recent years,the discoveries of dinosaur footprints have been successively reported from Dianshi Town,Zizhou City,Shaanxi Province.The footprints include the tracks of theropod,ornithopod and sauropod as well.Actually,the dinosaur footprints were found by local inhabitants much earlier in history,but not for science.The slabs bearing the dinosaur footprints were collected for domestic use,such as building stones,millstones,cellar covers,sheepfold fences,windlass holders,etc.This paper is to describe the dinosaur footprints on both sides of three slabs used for cellar covers,sheepfold fences and windlass holders by the local people.24 dinosaur footprints and 4 trackways have been recognized and all of them belong to theropod.Four kinds of dinosaur footprints are identified,including 1 new ichnogenus and 2 new ichnospecies:(1)Shanbeipus caudatus ichnogen.et ichnosp.nov.;(2)Pengxianpus yulinensis ichnosp.nov.;(3)Eubrontes ichnosp;(4)Kayentapus ichnosp.Dinosaur-footprint-bearing beds were initially identified as the Fuxian Formation of the Lower Jurassic.Multipal dinosaur footprints associated with fragment plant fossils suggest a humid fluviolacustrine environment setting in the Ordos Basin during the early period of the Jurassic. | WANG Baopeng LI Jianjun BAI Zhiqiang GAO Junmin DONG Shurong HU Bailin ZHAO Suiqin CHANG Jieqiong | 2016 | Acta Geologica Sinica(English Edition)2016，90，1： | 2 |
| 14 | Synthesis of super-fine L1_(0)-FePt nanoparticles with high ordering degree by two-step sintering under high magnetic field显示文摘Super-fine L1_(0)-Fe Pt nanoparticles(NPs)with high ordering degree were successfully prepared by a modified two-step sintering method,which includes low-temperature pre-sintering,and the high magnetic field(HMF)assisted post-sintering processes.The particle size of the L1_(0)-FePt NPs was obviously refined by lowering the sintering temperature.By applying the HMF during the post-sintering process,the fine size characteristics of L1_(0)-Fe Pt NPs were retained,and the ordering degree was significantly improved.The L1_(0)-Fe Pt NPs with sizes of about 4.5 nm,ordering degree of 0.940,and coercivity of 22.01 k Oe were obtained by this two-step sintering under a magnetic field of 12 T.The mechanism investigation of HMF enhancing the ordering degree indicates that the HMF enhances lattice distortion and magnetization energy(Zeeman energy).The enhanced lattice distortions cause high stress existing in the lattice,which can effectively promote the disordered-order transition.When the magnetic field reaches to 3 T,the Zeeman energy of the NPs is higher than the thermal disturbing energy of the NPs,and the magnetization effect is stronger.Therefore,the HMF(higher than 3 T)can obviously improve the disorder-order transition by lowering the energy barrier and accelerating the orderly diffusions of atoms.The HMF is a promising assistant to synthesize the L1_(0)-phase NPs with both of high ordering degree and super-fine size. | Dong Zhao Xiaoyang Wang Ling Chang Wenli Pei Chun Wu Fei Wang Luran Zhang Jianjun Wang Qiang Wang | 2021 | Journal of Materials Science & Technology2021，，14： | 2 |
| 15 | Structural insights into the catalytic mechanism of aldehyde-deformylating oxygenases显示文摘在 cyanobacteria 发现的丰满的 alk (a/e ) ne 生合成小径为 biofuel 生产作为一条有希望的其他的途径在最近的年里获得了巨大的注意。Cyanobacterial aldehyde-deformylating oxygenase (cADO ) 催化 C 的变换,潜水艇 class= “ a-plus-plus ” > n 丰满的醛到它的相应 C < 潜水艇 class= “ a-plus-plus ” > n-1 alk (a/e ) ne,是在那条小径的关键酶。由于它的低活动,由 cADO 的 alk (a/e ) ne 生产是一个低效的过程。cADO 的以前的生物化学、结构的调查在它的催化反应上提供了一些信息。然而,它的催化过程的细节仍然保持不清楚。这里,我们从 Synechococcus 报导 cADO 的五水晶结构伸长在两种它的没有铁、包铁的形式的紧张 PCC7942,在它的催化过程期间代表不同状态。结构的比较和功能的酶试金显示那 Glu144,协调铁的残余之一,在 cADO 的催化反应起一个重要作用。而且, Glu144 住的螺旋展出在 cADO 结构与 di 铁中心的不同有约束力的状态相关的二不同符合构造。因此,我们的结果为 cADO di 铁中心的高度易变的特征提供结构的解释,我们建议它与它的低酶的活动有关。根据我们的结构、生物化学的数据, cADO 的一个可能的催化过程被建议,它能与改进活动帮助 cADO 的设计。 | Cheniun Jia Mei Li Jianjun Li Jingjing Zhang Hongmei Zhang Peng Cao Xiaowei Pan Xuefeng LU Wenrui Chang | 2015 | Protein & Cell2015，6，1： | 1 |
| 16 | A novel radio-over-fiber configuration using optical phase modulator to Generate an optical mm-Wave and centralized lightwave for uplink connection显示文摘 | Zhensheng Jia Ting Wang Gee -Kung Chang | 2007 | IEEE Photonics Technology Letters2007，，3： | 1 |
| 17 | A dynamically reeonfigurable folded-path time delay buffer for optical packets switching显示文摘 | Yong Kee Yeo Jianjun Y Gee Kung Chang | 2004 | J Photon Technol Lett2004，16，11： | 1 |
| 18 | Arabidopsis ovate family protein 1 is a transcriptional repressor that suppresses cell elongation显示文摘 | Wang Shucai Chang Ying Guo Jianjun | 2007 | The Plant Journal2007，50，5： | 1 |
| 19 | Optical Millimeter- wave Generation or Up-conversion Using External Modulators 显示文摘 | YU Jianjun JIA Zhensheng CHANG Geekung | 2006 | IEEE Photonics Technology Letters2006，18，1： | 1 |
| 20 | A dynamically reconfigurable folded-path time delay buffer for optical packets switching显示文摘 | Yong-Kee Yeo Jianjun Yu Gee-Kung Chang | 2004 | IEEE Photon Technol Lett2004，16，11： | 1 |
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