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| 1 | Cardiotoxicity of 5-fluorouracil and capecitabine in Chinese patients: a prospective study显示文摘Background:5-Fluorouracil(5-FU)and capecitabine-associated cardiotoxicity ranging from asymptomatic electro-cardiography(ECG)abnormalities to severe myocardial infarction has been reported in a number of studies,but such cardiotoxicity in Chinese patients with malignant diseases has not been investigated to date.In the present study,we aimed to prospectively evaluate the incidence rates and clinical manifestations of 5-FU-and capecitabine-associated cardiotoxicity in cancer patients recruited from multiple centers in China.Methods:Among the 527 patients who completed the study,196 received 5-FU-based chemotherapy and 331 received capecitabine-based chemotherapy as either first-line or adjuvant therapy.Adverse events were reported during the treatment and up to 28 days of follow-up.Outcome measures included ECG,myocardial enzymes,cardiac troponin,brain natriuretic peptide and echocardiography.Univariate analysis and logistic regression were performed for subgroup analysis and identification of significant independent variables that are associated with cardiotoxicity of both agents.Results:In total,161 of 527 patients(30.6%)experienced cardiotoxicity.The incidence rate of cardiotoxicity was 33.8%(112/331)in the capecitabine group,which was significantly higher than the rate of 25%(49/196)in the 5-FU group(P=0.0042).110/527 patients(20.9%)suffered arrhythmia,105/527(19.9%)developed ischemic changes,while only 20/527 patients(3.8%)presented heart failure and 6/527 patients(1.1%)had myocardial infarction.Pre-existing cardiac disease,hypertension,capecitabine-based chemotherapy and duration of treatment were identified as sig-nificant risk factors associated with cardiotoxicity.The odds ratio were 15.7(prior history of cardiac disease versus no history),1.86(capecitabine versus 5-FU),1.06(5-8 versus 1-4 chemotherapy cycles)and 1.58(hypertension versus no hypertension),respectively.Conclusions:Cardiotoxicity induced by fluoropyrimidines in the Chinese population may be underestimated in clini-cal practice.Close monitoring of patients is recommended,especially for those patients at high risk for cardiotoxicity.Possible risk factors are duration of treatment,capecitabine-based chemotherapy,pre-existing cardiac diseases and hypertension.Trial registration This study was initiated on January 22,2014 and has been retrospectively registered with the registra-tion number ChiCTR1800015434 . | Jianjun Peng Chao Dong Chang Wang Weihua Li Hao Yu Min Zhang Qun Zhao Bo Zhu Jun Zhang Wenliang Li Fenghua Wang Qiong Wu Wenhao Zhou Ying Yuan Meng Qiu Gong Chen | 2018 | Cancer Communications2018，38，1： | 23 |
| 2 | Aflatoxin B1, zearalenone and deoxynivalenol in feed ingredients and complete feed from different Province in China显示文摘Background: The current study was carried out to provide a reference for monitory of aflatoxin B_1(AFB_1),zearalenone(ZEN) and deoxynivalenol(DON) contamination in feed ingredients and complete feeds were collected from different Province in China from 2013 to 2015.Methods: A total of 443 feed ingredients, including 220 corn, 24 wheat, 24 domestic distillers dried grains with soluble(DDGS), 55 bran, 20 wheat shorts and red dog, 37 imported DDGS, 34 corn germ meal and 29 soybean meal as well as 127 complete feeds including 25 pig complete feed(powder), 90 pig complete feed(pellet), six duck complete feed and six cattle complete feed were randomly collected from different Province in China,respectively, by high-performance chromatography in combined with UV or fluorescence analysis.Results: The incidence rates of AFB_1, ZEN and DON contamination of feed ingredients and complete feeds were80.8, 92.3 and 93.9 %, respectively. The percentage of positive samples for DON ranged from 66.7 to 100 %.Domestic DDGS and imported DDGS presented the most serious contamination AFB_1, ZEN and DON contamination levels of feeds ranged from 61.5 to 100 %, indicated that serious contamination over the studied 3-year period.Conclusion: The current data provide clear evidence that AFB_1, ZEN and DON contamination of feed ingredients and complete feeds in different Province in China is serious and differs over past 3-year. The use of corn, domestic DDGS, imported DDGS and corn germ meal, which may be contaminated with these three mycotoxins, as animal feed may triggered a health risk for animal. Feeds are most contaminated with DON followed by ZEN and AFB_1.Mycotoxins contamination in feed ingredients and complete feeds should be monitored routinely in China. | Li Wu Jianjun Li Yunhu Li Tiejun Li Qinghua He Yulong Tang Hongnan Liu Yongteng Su Yulong Yin Peng Liao | 2017 | Journal of Animal Science and Biotechnology2017，8，2： | 13 |
| 3 | Gibberellin homeostasis and plant height control by EUI and a role for gibberellin in root gravity responses in rice显示文摘米饭 Eui (伸长最高节间) 基因编码撤销的细胞色素 P450 monooxygenase 简历活跃赤霉素(气体) 。在这研究,我们在植物开发调查了 Eui 基因和它的角色的控制表示。我们发现 Eui 是外长的气体导致的差别并且 Eui 倡导者在维管束举办了最高的活动。eui 异种在在根冠的淀粉小粒开发是有缺点的,在表达式上的 Eui 提高了淀粉小粒产生和严肃回答,揭示为在根淀粉小粒开发和严肃回答的 GA 的一个角色。使用胚胎更少一半种子的实验揭示了那 RAmy1A, GAmyb 是高度起来当外长的 GA 不在时在 eui 糊粉房间调整了。另外, GA 生合成基因 GA3ox1 和 GA20ox2 是调整的 down, GA2ox1 起来在 eui 调整了幼苗。这些结果显示 EUI 涉及 GA 动态平衡,不是在仅仅内部在出发阶段的节点,而且在苗期,根和种子。扰乱 GA 动态平衡影响了表明基因 GID1 (赤霉素感觉迟钝的矮子 1 ) 的 GA 的表示, GID2 和 SLR1。有效地增加的 Eui 基因的转基因的 RNA 干扰种高度和改进标题性能。由对比,在米饭 GA 生合成基因 GA3ox2 和 GA20ox2 的倡导者下面的 Eui 的宫外的表示显著地减少了植物高度。这些结果证明 Eui 表示的细微增加能戏剧性地改变米饭形态学,显示在米饭的 Eui 基因的实际申请为一个高产潜力的分子的繁殖。 | Yingying Zhang Yongyou Zhu Yu Peng Dawei Yan Qun Li Jianjun Wang Linyou Wang Zuhua He | 2008 | Cell Research2008，18，3： | 10 |
| 4 | Nine-month angiographic and two-year clinical follow-up of polymer-free sirolimus-eluting stent versus durable-polymer sirolimus-eluting stent for coronary artery disease: the Nano randomized trial显示文摘 | Zhang Yaojun Chen Fang Takashi Muramatsu Xu Bo Li Zhanquan Ge Junbo He Qing Yang Zhijian Li Shumei Wang Lefeng Wang Haichang He Ben Li Kang Qi Guoxian Li Tianchang Zeng Hesong Peng Jianjun Jiang Tieming Zeng Qiutang Zhu Jianhua Fu Guosheng Christos V. Bourantas Patrick W. Serruys Huo Yong | 2014 | Chinese Medical Journal2014，，11： | 8 |
| 5 | A novel approach to melt purification of magnesium alloys显示文摘A novel low-cost method for melt purification of magnesium alloys,the melt self-purifying technology(MSPT),has been developed successfully based on a low temperature melt treatment(LTMT)without adding any fluxes.The iron solubility in the molten liquid of magnesium and its alloys,and the settlement velocity of iron particles were calculated.It is shown that the low temperature melt treatment is an effective method to decrease the impurity Fe content in magnesium and its alloys.Without any additions,the Fe content in the AZ31 alloy was reduced to 15 ppm from the initial 65 ppm,and the Fe content in the AZ61 melt was decreased to 20 ppm from the initial 150 ppm after the low temperature melt treatment.The results also showed that the Fe content in AM60 and AM50 dropped to 15 and 18 ppm,respectively,from the initial 150 ppm after the low temperature melt treatment.For ZK 60,the Fe content in the melt down to less than 5 ppm was achieved.After the low temperature melt treatment,the Si content in the above alloys was also decreased obviously. | Fusheng Pan Xianhua Chen Tao Yan Tingting Liu Jianjun Mao Wei Luo Qin Wang Jian Peng Aitao Tang Bin Jiang | 2016 | Journal of Magnesium and Alloys2016，4，1： | 5 |
| 6 | Modelling of dynamic recrystallization kinetics of 300M steel at high strain rates during hot deformation显示文摘The flow curves of 300M steel exhibit a transition from stress peak presence to stress peak absence as the strain rate increases. It is difficult to establish dynamic recrystallization(DRX) kinetics models suitable for strain rates where there are no stress peaks in the flow curves using the existing Avrami equation, and the optimal processing parameters for forging can be scarcely acquired.In this study, the high-temperature flow and DRX behavior of 300M steel are investigated by performing isothermal compression tests at temperatures between 1173–1423K with strain rates between 0.001–50 s-1. Distinct stress peaks can be found in the flow curves at low strain rates, and the average grain size decreases with the increase in the strain rate at the same temperature. The DRX mechanism is a discontinuous DRX, and the grain boundary migration plays an important role in the DRX process. In contrast, no stress peak is observed in the flow curves at high strain rates, and the average grain size no longer decreases with the strain rate increase at the same temperature. The DRX mechanism in this case is a continuous DRX. The demarcated strain rate is calculated based on the characteristics of the obtained flow curves and grain sizes. The recrystallization volume fraction model and prediction grain size model at high strain rates are established. In combination with the existing DRX kinetics models at low strain rates, the processing parameters can be optimized to produce components with excellent mechanical properties. | GUO Peng DENG Lei WANG XinYun LI JianJun | 2019 | Science China(Technological Sciences)2019，62，9： | 5 |
| 7 | MiR-125a regulates chemo-sensitivity to gemcitabine in human pancreatic cancer cells through targeting A20显示文摘胰腺的 ductal 腺癌(PDAC ) 是最致命的人之一恶意的疾病和在中国的癌症相关的死亡的第六个领先的原因。Gemcitabine 是与 PDAC 为病人的辩解的治疗使用的唯一的首要的化学疗法的代理人,但是 chemo 抵抗限制他们的功效。这里,当时,我们证明 miR-125a 在 chemo 抵抗的 SW1990GZ 房间是起来调整的与 SW1990 房间相比。miR-125a 的在表示上在 SW1990 房间增加了 chemo 抵抗到 gemcitabine,当在 SW1990GZ 房间的 miR-125a 的下面规定增加了 chemo 敏感到 gemcitabine 时。由使用生物信息学分析工具(Targetscan ) , A20 基因的 3 untranslated 区域(3UTR ) 被发现是 miR-125a 的一个目标。酶记者试金进一步证实 A20 3UTR 是 miR-125a 的一个直接目标。在 SW1990 房间的 A20 的在表示上在支持的 SW1990 房间 A20 增加了 chemo 敏感到 gemcitabine,当击倒时 chemo 抵抗到 gemcitabine。最后,在从 chemo 敏感的病人的胰腺的癌症纸巾的 miR-125a 的表示水平来自 chemo 抵抗的病人是比那显著地低的,并且相反地与 A20 mRNA 层次被相关。在结论,我们的结果建议 miR-125a 通过指向 A20 在胰腺的房间把 chemo 抵抗提升到 gemcitabine,它可以为癌症治疗提供新奇治疗学的目标或分子的 biomarkers 并且改进肿瘤诊断或治疗学的回答的预言。 | Jie Yao Zhennan Li Xiaodong Wang Peng Xu Long Zhao Jianjun Qian | 2016 | Acta Biochimica et Biophysica Sinica2016，48，2： | 5 |
| 8 | Effect of Al on Microstructures and Mechanical Properties of the Ultrahigh Carbon Steels显示文摘In this research, we tried to find a simple processing method to break up the network carbides in ultrahigh carbon steels (UHCS). Our results revealed that Al addition was favorable to the decrease in the proeutectoid carbides, the pearlite-colony size and the pearlitic interlamellar spacing of the forged microstructures, and that a fully-pearlitic structure was obtained in the UHCS containing 1.6 wt pct Al. The quenching-and-tempering process resulted in fine microstructure in those steels. On the other hand, the strength of the UHCSs increased with the increase of the Al content, and the highest strength was obtained at the UHCS with 1.6 wt pct Al. The UHCSs with Al contents higher than 1.3 wt pct showed a high tensile strength of more than σb=1000 MPa and good ductility of higher than δ5=10% at ambient temperature. | Huifen PENG, Baoqi WANG, Jianjun ZHANG, Xiaoyan SONG, Xiaoli MA and Nanju GUSchool of Materials Science & Engineering, Hebei University of Techonology, Tianjin 300130, China | 2004 | Journal of Materials Science & Technology2004，20，5： | 5 |
| 9 | Elastic Scattering of 7Be on Pb Target显示文摘 | Yang Yanyun Wang Jiansong Wang Qi Huang Meirong Ma Junbing Ma Peng Cao Xiguang Han Jianlong Bai Zhen Jin Shilong Hu Qiang Jin Lei Chen Jiangbo Zhang Xueying Chen Ruofu Hu Zhengguo Xu Shiwei Zhen Chuan Xu Zhiguo Xu Hushan Duan Liming Sun Zhiyu Chen Zhiqiang He Jianjun Li Songlin Lei Xiangguo Fu Fen Zhang Xueheng Yuan Xiaohua Du Chengming Yan Xinshuang Hu Jun Tang Shuwen Ye Ruiping Yang Kun Shi Fudong Zhang Wei Chen Ze Li Long Xu Xing Liu Longxiang Zhang Liyong Lin Qingyun Gou Boxing Xu Ge Zhou Xionghong Zhang Yuhu Xiao Guoqing | 2011 | IMP & HIRFL Annual Report2011，，1： | 4 |
| 10 | Charge‑Transfer Resonance and Electromagnetic Enhancement Synergistically Enabling MXenes with Excellent SERS Sensitivity for SARS‑CoV‑2 S Protein Detection显示文摘The outbreak of coronavirus disease 2019 has seriously threatened human health.Rapidly and sensitively detecting SARSCoV-2 viruses can help control the spread of viruses.However,it is an arduous challenge to apply semiconductor-based substrates for virus SERS detection due to their poor sensitivity.Therefore,it is worthwhile to search novel semiconductor-based substrates with excellent SERS sensitivity.Herein we report,for the first time,Nb2C and Ta2C MXenes exhibit a remarkable SERS enhancement,which is synergistically enabled by the charge transfer resonance enhancement and electromagnetic enhancement.Their SERS sensitivity is optimized to 3.0×10^6 and 1.4×10^6 under the optimal resonance excitation wavelength of 532 nm.Additionally,remarkable SERS sensitivity endows Ta2C MXenes with capability to sensitively detect and accurately identify the SARS-CoV-2 spike protein.Moreover,its detection limit is as low as 5×10^−9 M,which is beneficial to achieve real-time monitoring and early warning of novel coronavirus.This research not only provides helpful theoretical guidance for exploring other novel SERS-active semiconductor-based materials but also provides a potential candidate for the practical applications of SERS technology. | Yusi Peng Chenglong Lin Li Long Tanemura Masaki Mao Tang Lili Yang Jianjun Liu Zhengren Huang Zhiyuan Li Xiaoying Luo John RLombardi Yong Yang | 2021 | Nano-Micro Letters2021，13，3： | 3 |
| 11 | Sound propagation from the shelfbreak to deep water显示文摘Motivated by a phenomenon in an experiment conducted in the Northwestern Pacific indicating that the energy of the received signal around the sound channel axis is much greater than that at shallower depths,we study sound propagation from the transitional area(shelfbreak)to deep water.Numerical simulations with different source depths are first performed,from which we reach the following conclusions.When the source is located near the sea surface,sound will be strongly attenuated by bottom losses in a range-independent oceanic environment,whereas it can propagate to a very long range because of the continental slope.When the source is mounted on the bottom in shallow water,acoustic energy will be trapped near the sound channel axis,and it converges more evidently than the case where the source is located near the sea surface.Then,numerical simulations with different source ranges are performed.By comparing the relative energy level in the vertical direction between the numerical simulations and the experimental data,the range of the air-gun source can be approximated. | QIN JiXing ZHANG RenHe LUO WenYu PENG ZhaoHui LIU JianJun WANG DeJun | 2014 | Science China(Physics,Mechanics & Astronomy)2014，57，6： | 3 |
| 12 | Progress of Jinping Underground laboratory for Nuclear Astrophysics(JUNA)显示文摘Jinping Underground laboratory for Nuclear Astrophysics(JUNA) will take the advantage of the ultra-low background of CJPL lab and high current accelerator based on an ECR source and a highly sensitive detector to directly study for the first time a number of crucial reactions occurring at their relevant stellar energies during the evolution of hydrostatic stars. In its first phase, JUNA aims at the direct measurements of^(25)Mg(p,γ)^(26)Al,^(19)F(p,α)^(16)O,^(13)C(α,n)^(16)O and ^(12)C(α,γ)^(16)O reactions. The experimental setup,which includes an accelerator system with high stability and high intensity, a detector system, and a shielding material with low background, will be established during the above research. The current progress of JUNA will be given. | WeiPing Liu ZhiHong Li JiangJun He XiaoDong Tang Gang Lian Zhu An JianJun Chang Han Chen QingHao Chen XiongJun Chen ZhiJun Chen BaoQun Cui XianChao Du ChangBo Fu Lin Gan Bing Guo GuoZhu He Alexander Heger SuQing Hou HanXiong Huang Ning Huang BaoLu Jia LiYang Jiang Shigeru Kubono JianMin Li KuoAng Li Tao Li YunJu Li Maria Lugaro XiaoBing Luo HongYi Ma ShaoBo Ma DongMing Mei YongZhong Qian JiuChang Qin Jie Ren YangPing Shen Jun Su LiangTing Sun WanPeng Tan Isao Tanihata Shuo Wang Peng Wang YouBao Wang Qi Wu ShiWei Xu ShengQuan Yan LiTao Yang Yao Yang XiangQing Yu Qian Yue Sheng Zeng HuanYu Zhang Hui Zhang LiYong Zhang NingTao Zhang QiWei Zhang Tao Zhang XiaoPeng Zhang XueZhen Zhang ZiMing Zhang Wei Zhao Zuo Zhao Chao Zhou | 2016 | Science China(Physics,Mechanics & Astronomy)2016，59，4： | 3 |
| 13 | A BODIPY-based Fluorescent Probe for Thiophenol显示文摘 | Dongxiang Zhang Ning Xu Liman Xian Haoying Ge Jiangli Fan Jianjun Du Xiaojun Peng | 2018 | Chinese Journal of Chemistry2018，36，2： | 3 |
| 14 | Serum uric acid is a risk factor for large-artery atherosclerosis cerebral infarction显示文摘Using the Trial of Org 10172 in Acute Stroke Treatment (TOAST) classification for acute ischemic stroke, 371 patients with either acute large-artery atherosclerosis or small-artery oc-clusion cerebral infarction were recruited to investigate the potential impact of elevated serum uric acid on cerebrovascular disorders. The results showed that patients who have suffered from large-artery atherosclerosis, relative to small-artery occlusion patients, were characterized by elevated serum uric acid but reduced high-density lipoprotein cholesterol and triglyceride levels. Logistic regression showed that elevated uric acid and lower triglyceride levels were the main risk factors for patients with large-artery atherosclerosis. The findings of this study suggest that hyperuricemia may be a risk factor for stroke. | Jianjun Guo Qingyu Shen Jie Li Xiaoming Rong Ying Peng Yamei Tang | 2011 | Neural Regeneration Research2011，6，36： | 3 |
| 15 | 5-氟尿嘧啶和卡培他滨对中国患者的心脏毒性:一项前瞻性研究显示文摘背景与目的已有许多研究报道5-氟尿嘧啶(5-Fluorouracil,5-FU)和卡培他滨相关的心脏毒性,严重程度从无症状心电图(electrocardiography,ECG)异常到严重心肌梗塞而不同。目前为止,对中国恶性肿瘤患者的这种心脏毒性尚无研究。本研究旨在前瞻性地对多个中心招募的癌症患者进行5-FU和卡培他滨相关心脏毒性的发生率和临床表现进行评估。方法在完成研究的527例患者中,196例接受基于5-FU的化疗,331例接受基于卡培他滨的化疗并以其为一线或辅助治疗。在治疗期间和长达28 d的随访期间对所发生的不良反应进行记录。疗效测量指标包括心电图、心肌酶、心肌肌钙蛋白、脑钠肽和超声心动图。使用单因素分析和logistic回归方法进行亚组分析和鉴定与两种药物的心脏毒性相关的显著性独立变量。结果 527例患者中有161例(30.6%)出现心脏毒性。卡培他滨组的心脏毒性发生率为33.8%(112/331),显著高于5-FU组25%(49/196)的发生率(P=0.0042)。110/527患者(20.9%)发生心律失常,105/527(19.9%)发生缺血性改变,而只有20/527患者(3.8%)出现心力衰竭,6/527患者(1.1%)出现心肌梗塞。既往的心脏病、高血压、卡培他滨为基础的化疗和治疗时间被确定为与心脏毒性相关的显著风险因素。优势比分别为15.7(心脏病史vs.无病史)、1.86(卡培他滨vs. 5-FU)、1.06(5–8个化疗周期vs. 1–4个化疗周期)和1.58(高血压vs.无高血压)。结论氟嘧啶类药物在中国人群中引起的心脏毒性可能在临床实践中被低估。建议密切监测患者,尤其是对心脏毒性高风险的患者。可能的风险因素包括治疗持续时间、基于卡培他滨的化疗、既往心脏病史和高血压史。 | Jianjun Peng Chao Dong Chang Wang Weihua Li Hao Yu Min Zhang Qun Zhao Bo Zhu Jun Zhang Wenliang Li Fenghua Wang Qiong Wu Wenhao Zhou Ying Yuan Meng Qiu Gong Chen | 2018 | 癌症2018，37，10： | 3 |
| 16 | Preventing crash in stock market:The role of economic policy uncertainty during COVID‑19显示文摘This paper investigates the impact of economic policy uncertainty(EPU)on the crash risk of US stock market during the COVID-19 pandemic.To this end,we use the GARCHS(GARCH with skewness)model to estimate daily skewness as a proxy for the stock market crash risk.The empirical results show the significantly negative correlation between EPU and stock market crash risk,indicating the aggravation of EPU increase the crash risk.Moreover,the negative correlation gets stronger after the global COVID-19 outbreak,which shows the crash risk of the US stock market will be more affected by EPU during the epidemic. | Peng‑Fei Dai Xiong Xiong Zhifeng Liu Toan Luu Duc Huynh Jianjun Sun | 2021 | Financial Innovation2021，7，1： | 2 |
| 17 | Desert vegetation distribution and species-environment relationships in an oasis-desert ecotone of northwestern China显示文摘Environmental heterogeneity significantly affects the structure of ecological communities.Exploring vegetation distribution and its relationship with environmental factors is essential to understanding the abiotic mechanism(s)driving vegetation succession,especially in the ecologically fragile areas.In this study,based on the quantitative analysis of plant community and environmental factors in 68 plots at 10 different transects in the Minqin oasis-desert ecotone(ODE)of northwestern China,we investigated desert vegetation distribution and species-environment relationships using multivariate analysis.Two-way indicator species analysis(TWINSPAN),detrended correspondence analysis(DCA),and canonical correspondence analysis(CCA)methods were used.A total of 28 species,belonging to 27 genera in 8 families,were identified.Chenopodiaceae,Zygophyllaceae,Gramineae,and Leguminosae were the largest families.Annual and perennial herbs accounted for 28.60%of the total number of plants,while shrubs(42.90%)were the most dominant.Nitraria tangutorum was the constructive species of the desert plant community.We divided the 68 plots surveyed in this study into 7 community types,according to the results of TWINSPAN.The distribution of these 7 communities in the DCA ordination graph showed that species with a similar ecotype were clustered together.Results of CCA indicated that groundwater was the dominant factor influencing vegetation distribution,while distance between plot and oasis(Dis)and soil electrical conductivity(EC)were the local second-order factors.Our study suggests that optimizing the utilization of groundwater in oases is key to controlling the degradation of desert vegetation.The favorable topographic conditions of sand dunes should be fully utilized for vegetal dune stabilization,and the influence of soil salinity on the selection of afforestation tree species should be considered. | ZHAO Peng QU Jianjun XU Xianying YU Qiushi JIANG Shengxiu ZHAO Heran | 2019 | Journal of Arid Land2019，11，3： | 2 |
| 18 | Carboniferous Highly Fractionated I-type Granites from the Kalamaili Fault Zone, Eastern Xinjiang, NW China: Petrogenesis and Tectonic Implications显示文摘Carboniferous magmatism is one of the most important tectonothermal events in the Central Asian Orogenic Belt(CAOB). However, the final closure time of the Kalamaili Ocean between East Junggar and Harlik Mountain is still debated. Early Carboniferous(332 Ma) and late Carboniferous(307-298 Ma) granitic magmatism from Kalamaili fault zone have been recognized by LA-ICP-MS zircon U-Pb dating. They are both metaluminous highly fractionated I-type and belong to the high-K calc-alkaline. The granitoids for early Carboniferous have zircon εHf(t) values of-5.1 to +8.5 with Hf model ages(TDM2) of 1.78-0.83 Ga, suggesting a mixed magma source of juvenile material with old continental crust. Furthermore, those for late Carboniferous have much younger heterogeneous zircon εHf(t) values(+5.1 to +13.6) with Hf model ages(TDM2=1.03-0.45 Ga) that are also indicative of juvenile components with a small involvement of old continental crust. Based on whole-rock geochemical and zircon isotopic features, these high-K granitoids were derived from melting of heterogeneous crustal sources or through mixing of old continental crust with juvenile components and minor AFC(assimilation and fractional crystallization). The juvenile components probably originated from underplated basaltic magmas in response to asthenospheric upwelling. These Carboniferous highly fractionated granites in the Kalamaili fault zone were probably emplaced in a post-collisional extensional setting and suggested vertical continental crustal growth in the southern CAOB, which is the same or like most granitoids in CAOB. This study provides new evidence for determining the post-accretionary evolution of the southern CAOB. In combination with data from other granitoids in these two terranes, the Early Carboniferous Heiguniangshan pluton represents the initial record of post-collisional environment, suggesting that the final collision between the East Junggar and Harlik Mountain might have occurred before 332 Ma. | SONG Peng WANG Tao TONG Ying ZHANG Jianjun HUANG He ZHANG Lei QIN Qie SHEN Huan | 2019 | Acta Geologica Sinica(English Edition)2019，93，5： | 2 |
| 19 | Extraction and identification of the chyme proteins in the digestive tract of growing pigs显示文摘This study aimed to explore the rule of degradation of dietary proteins by identifying chyme proteins in different segments of the digestive tract of growing pigs, using proteomics techniques. Six growing pigs were fed a corn-soybean meal-based diet for 7 days. The feedstuff and chyme proteins were separately extracted and separated with SDS-PAGE. 2 D LCMS/MS combined with protein database searching identified 1,513 proteins in different segments of the gastrointestinal tract, the number of identified exogenous proteins gradually decline from the stomach to colon, with large amounts in the duodenum to the large intestine.More corn proteins than soybean proteins were identified both in the feedstuff and chyme, and these were significantly decreased after digestion in the stomach. More membrane proteins than non-membrane proteins were identified in whole digestive tract.These results regarding the profiles of chyme proteins in different segments of the gastrointestinal tract would provide useful information for optimizing feed formula in pigs. | Jianjun Li Bie Tan Yulong Tang Peng Liao Kang Yao Peng Ji Yulong Yin | 2018 | Science China(Life Sciences)2018，61，11： | 2 |
| 20 | 2-14 Investigation of the Thermonuclear 18Ne(α, p)21Na Reaction Rate via Resonant Elastic Scattering of 21Na + p显示文摘A nuclear astrophysics experiment was performed at CRIB (CNS low-energy Radioactive-Ion Beam separator)on Mar. 2011. The goal of this experiment is to study the reaction rate of 18Ne(,p)21Na reaction, which mightbe a key breakout reaction from the hot CNO cycle to rp-process in X-ray burst and nova. Yet its reaction rate ispoorly known.Explosive hydrogen burning is thought to be the main source of energy generation and a source of nucleosynthesisin X-ray burst and nova[1;2]. For example, XRBs are characterized by a sudden increase of X-ray emission withinonly a few seconds to a total energy output of about 1040 ergs, which is observed to repeat with some regularity.The recurrence time for single bursts can range from hours to days at the typical temperature of 0.4~2 GK. Thebursts have been interpreted as being generated by thermonuclear runaway on the surface of a neutron star thataccretes H- and He-rich material from a less evolved companion star in a close binary system. As shown in Fig. 1,under its typical temperature, the hydrogen burning in X-ray burst occurs from the hot CNO cycle: | Zhang Liyong He Jianjun Xu Shiwei H.Yamaguchi S. Kubono Y.Wakabayashi Chen Size Hu Jun Ma Peng Y. Togano T. Hashimoto D. Kahl T. Teranishi Chen Ruofu Wang Hongwei Tian Wendong Guo Bing S. Hayakawa N. Iwasa T. Yamada T. Komatsubara | 2014 | IMP & HIRFL Annual Report2014，，1： | 2 |
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