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| 1 | Microbialite of anoxic condition from Permian-Triassic transition in Guizhou,China显示文摘Spherical microfossils are present in the Hindeodus parvus zone of the Lower Triassic in Ziyun,Guizhou Province. They generally range from 0.15 to 0.30 mm across,with micritic wall and filled by micro-sparry calcites,and are evenly scattered in micritic matrix. Their abundance makes the rock as-signed to microbialites. The accompanied organisms include ostracods and algal mat,but no gastro-pods or bivalves. Presence of small (<7 μm) pyrite framboids indicates that this bed formed in anoxic conditions. In some sections,this bed is overlain and underlain by tidal-flat micritic limestone with microgastropods and small burrows. Occurrence only in deposits on reef top indicates that the micro-bial organism was benthic,and needed sunlight in life. The size of the microbial fossil exceeds that of any bacteria or cyanobacteria. Thus,it does not belong to these two phyla. It may belong to lower green algae,and is assigned to a new species in a new genus,Ziyunosphaeridium sinensis gen. et sp. nov. Up to now,the rocks described as microbialites from the Permian-Triassic transition include six types: (1) porous micritic limestone such as that descried from Japan by Sano and Nakashima (1997),(2) limestone with rich globular microfossils such as that described from the Nanpanjiang Basin in China by Lehrmann (1999),(3) dendroidal limestone such as that described from the vicinity of Chongqing by Kershaw et al. (1999),(4) spherical microbial limestone adapted to anoxic environments described from Ziyun,Guizhou reported in this paper,(5) limestone with cyanobacterial fossils such as that described by Wang et al. (2005),and (6) stromatolites. All these microbialites are not reefs in the proper sense,and the argument that Permian reef ecosystems extended into the Mesozoic is incorrect. | WU YaSheng JIANG HongXia YANG Wan FAN JiaSong | 2007 | Science China Earth Sciences2007，50，7： | 18 |
| 2 | PREPARATIOPREPARATION OF 1-OCTENE BY ETHYLENE TETRAMERIZATION WITH HIGH SELECTIVITY显示文摘Two novel PNP ligands have been synthesized and characterized by 1H-NMR, elemen- tal analysis, and mass spectra. In combination with Cr(Ⅲ ) and cocatalyst MAO, they generate active catalytic systems that tetramerize ethylene with both high catalytic activity and high selectivity to produce 1-octene. The results show that these catalyst sys- tems are able to catalyze ethylene tetramerization, with high catalytic activity up to 0.89×106 g/mol Cr.h, and the selectivity of C8 in products is 72.52%, and the percentage of 1-olefins in the C8 cut is 97.87%. | JIANG Tao CHEN Hongxia NING Yingnan CHEN Wei | 2006 | Chinese Science Bulletin2006，51，5： | 13 |
| 3 | Ethylene tetramerization with a highly active and long-lifetime trinuclear diphenylphosphinoamine/Cr(III)/MAO catalyst显示文摘The synthesis and characterization of a novel trinuclear diphosphinoamine ligand 2 are reported. The ligand combined with Cr(III), activated with methylaluminoxane, lead to highly active and long-lifetime catalytic systems for the tetramerization of ethylene to form 1-octene. The effects of reaction temperature, reaction pressure, molar ratio of Al/Cr and bis(diphenylphosphino)amine/Cr on the catalytic activity and product selectivity were studied. Compared with its mononuclear analogue 1, ligand 2 showed a higher catalytic activity and longer lifetime for ethylene tetramerization in the presence of methylaluminoxane as cocatalyst. High molecular weight polyethylene was generated as a by-product with extremely broad molecular weight distributions. | JIANG Tao TAO YiQing GAO XiangLu MAO GuoLiang CHEN HongXia CAO ChenGang NING YingNan | 2012 | Chinese Science Bulletin2012，57，13： | 12 |
| 4 | Extinction pattern of reef ecosystems in latest Permian显示文摘Studies of two Permian-Triassic boundary (PTB) sections on top of a Changhsingian reef in Ziyun, Guizhou Province, southwestern China indicate that the end-Permian mass extinction of reef ecosystems occurred in two steps. The first step is the extinction of all stenotropic organisms such as calcisponges and fusulinids in the latest Permian (in the Clarkina yini conodont zone). The biota after the first extinction is simple, comprising eurytropic organisms including microgastropods, ostracods, and some small burrowing organisms, or only algal mats. At the beginning of the Early Triassic (i.e. the beginning of the Hindeodus parvus zone), the environments became anoxic, and the microgastropod dominated biota or algal mats disappeared, which constituted the second episode of the mass extinction. The biota after the second extinction comprises small spherical microproblematica, some kinds of specialized organisms tolerant of anoxic or oxygen-poor conditions. As the environments became oxygenated, the specialized biota was replaced by a microgastropod-dominated simple biota. When the environmental conditions improved further, the simple biota was replaced by a diverse biota with normal-sized ammonoids, bivalves, and gastropods, representing restoration of normal oceanic condi- tions. Comparison with PTB sections in Dolomites, Italy and Meishan, Zhejiang Province shows that non-reef ecosystems had a similar first episode of mass extinction in the latest Permian. In the case that oceanic anoxia happened, non-reef ecosystems had a second extinction episode similar to that of reef ecosystems. | WU YaSheng FAN JiaSong JIANG HongXia YANG Wan | 2007 | Chinese Science Bulletin2007，52，4： | 11 |
| 5 | Reproductive toxicity of organic extracts from petrochemical plant effluents discharged to the Yangtze River,China显示文摘Water pollution of the Yangtze River in China became one of challenges that the government is facing today.Increasing numbers of petrochemical plants were built along the river in past decades,and numbers of organic chemicals were discharged into the river.Our goal was to establish in vitro system on rat sertoli cells,spermatogenic cells and leydig cells to investigate the reproductive toxicity potential induced by organic extracts from petrochemical effluents.Our results showed that the organic extract depressed the viability(p<0.01) and destroyed the plasma membrane integrity of sertoli cells and spermatogenic cells to a certain degree.Accordingly,proportion of early apoptotic sertoli cells and late apoptotic spermatogenic cells increased significantly.Although significant morphological changes were not detected for leydig cells,the extract was observed to inhibit their testosterone production(p<0.01).Sertoli cells and spermatogenic cells appeared to be more sensitive and maybe the main targets of the key toxins.These results suggested that the in vitro system on rat testicular cells may be useful to predicate reproductive toxicity potential of organic extracts from petrochemical effluents.More attention should be paid to the petrochemical effluents,because long-term accumulation of these organic compounds in organisms may cause spermatogenesis malfunction and testosterone reduction. | Xiaoyi Wang Wei Shi Jiang Wu Yingqun Hao Guanjiu Hu Hongling Liu Xiaodong Han Hongxia Yu | 2010 | Journal of Environmental Sciences2010，22，2： | 7 |
| 6 | Filamentous cyanobacteria fossils and their signifi-cance in the Permian-Triassic boundary section at Laolongdong,Chongqing显示文摘The microbial communities blooming immediately after the end-Permian mass extinction represent abnormally extreme environments, and vary in different areas. In this study, filamentous cyanobacterial biota was found in the strata after the extinction in the famous Permian-Triassic boundary section at Laolongdong, Chongqing, southwest China. In thin sections, the filamentous cyanobacterial fossils are below 1 mm in length, and generally taper to one end, with the widest diameter up to 0.08 mm. Some of them are curved, indicating that they are soft in life. Their walls are composed of cryptocrystalline to microcrystalline calcites. The filaments have round cross section, and are internally filled with micrites and fine sparry calcites, which indicate that the filaments are originally empty. They are randomly dis-tributed in the rocks, but in some places, they tend to be distributed in radial pattern. The filamentous organisms are morphologically similar to Rivularia of Rivulariaceae, Cyanobacteria Phylum, but with calcified sheaths, and are tentatively regarded as an indeterminate new species in Rivularia: Rivularia sp. Cyanobacteria are photosynthetic autotrophic, and can survive in dysoxic condition. The blooming of this organism and the absence of other organisms may indicate that the environment was oxygen- deficient and shallow, since this photosynthetic autotrophic organism needed to live within photic zone. | JIANG HongXia WU YaSheng CAI ChunFang | 2008 | Chinese Science Bulletin2008，53，12： | 7 |
| 7 | Impaired tumor angiogenesis and VEGF- induced pathway in endothelial CD146 knockout mice显示文摘 | Qiqun Zeng Zhenzhen Wu Hongxia Duan Xuan Jiang Tao Tu Di Lu Yongting Luo Ping Wang Lina Song Jing Feng Dongling Yang Xiyun Yan | 2014 | Protein & Cell2014，5，6： | 6 |
| 8 | Patient-derived non-small cell lung cancer xenograft mirrors complex tumor heterogeneity显示文摘Objective:Patient-derived xenograft(PDX)models have shown great promise in preclinical and translational applications,but their consistency with primary tumors in phenotypic,genetic,and pharmacodynamic heterogeneity has not been well-studied.This study aimed to establish a PDX repository for non-small cell lung cancer(NSCLC)and to further elucidate whether it could preserve the heterogeneity within and between tumors in patients.Methods:A total of 75 surgically resected NSCLC specimens were implanted into immunodeficient NOD/SCID mice.Based on the successful establishment of the NSCLC PDX model,we compared the expressions of vimentin,Ki67,EGFR,and PD-L1 proteins between cancer tissues and PDX models using hematoxylin and eosin staining and immunohistochemical staining.In addition,we detected whole gene expression profiling between primary tumors and PDX generations.We also performed whole exome sequencing(WES)analysis in 17 first generation xenografts to further assess whether PDXs retained the patient heterogeneities.Finally,paclitaxel,cisplatin,doxorubicin,atezolizumab,afatininb,and AZD4547 were used to evaluate the responses of PDX models to the standard-of-care agents.Results:A large collection of serially transplantable PDX models for NSCLC were successfully developed.The histology and pathological immunohistochemistry of PDX xenografts were consistent with the patients’tumor samples.WES and RNA-seq further confirmed that PDX accurately replicated the molecular heterogeneities of primary tumors.Similar to clinical patients,PDX models responded differentially to the standard-of-care treatment,including chemo-,targeted-and immuno-therapeutics.Conclusions:Our established PDX models of NSCLC faithfully reproduced the molecular,histopathological,and therapeutic characteristics,as well as the corresponding tumor heterogeneities,which provides a clinically relevant platform for drug screening,biomarker discovery,and translational research. | Xuanming Chen Cheng Shen Zhe Wei Rui Zhang Yongsheng Wang Lili Jiang Ke Chen Shuang Qiu Yuanli Zhang Ting Zhang Bin Chen Yanjun Xu Qiyi Feng Jinxing Huang Zhihui Zhong Hongxia Li Guowei Che Kai Xiao | 2021 | Cancer Biology & Medicine2021，18，1： | 5 |
| 9 | Community replacement sequences and paleoenvironmental changes in reef areas of South China from Late Permian to Early Triassic exemplified by Panlongdong section in northeastern Sichuan Basin显示文摘The well-known Permian Changhsingian calcisponge reef located at Panlongdong section,Xuanhan county,northeastern Sichuan Basin has attracted wide attention.Due to severe dolomitization and poor quality of the fossils,the P-T boundary in this section is difficult to determine.This study,for the first time,recognized six communities in the Upper Permian Changhsingian Changxing Formation through the Lower Triassic Induan Feixianguan Formation of the Panlongdong section.They are Bryozoan-Archaeolithoporella-calcisponge Community,Calcareous green algae-foraminifer-crinoid Community,Microgastropod-foraminifer Community,Ostracod-microgastropod-cystic microbe Community,Ostracod-small brachiopod Community,and Non-calcified cyanobacteria Community.By using community replacement and palaeoenvironmental analysis,for the first time,we set the P-T boundary of the Panlongdong section at the middle of the calcimicrobialite containing cystic microbes.The community replacement sequence in the Panlongdong section is similar to that in other contemporaneous sections in reef areas of South China,indicating universal palaeoenvironmental changes during the Permian-Triassic transition.The results show that:(1)Changhsingian calcisponge reefs in South China generally vanished before the mass extinction and may be related to the large regression in the Late Permian.(2)The Calcareous green algae-foraminifer-crinoid Community replaced reef community and continued till the mass extinction.The mass extinction was probably related to the global sea-level drop.(3)The first aftermath community was dominated by specialized microgastropods,followed by the microbes,and then by the specialized microgastropods and small brachiopods.The succession of the three communities reflected the change in environmental conditions from dysoxic to anoxic and again to dysoxic.(4)In the Early Triassic,the relict community in shallow sea had very low diversity and low abundance,and was dominated by crinoids,gastropods,and bivalves. | LIU LiJing JIANG HongXia WU YaSheng CAI ChunFang | 2014 | Science China Earth Sciences2014，57，5： | 4 |
| 10 | Rapid and sensitive determination of fatty acids in edible oil by liquid chromatography-electrospray ionization tandem mass spectrometry显示文摘A sensitive and robust on-line LC/MS method was developed for quantitative determination of linoleic acid,docosahexaenoic acid and docosanoic acid from edible oil samples.The oil samples were dissolved in chloroform-isopropyl alcohol(20:80,v:v)solution and the three fatty acids were separated by HPLC with a C4 column using 10 mmol/L ammonium acetate-isopropyl alcohol-acetonitrile(20:40:40,v:v:v)mobile phase in isocratic elution.Electrospray ionization mass spectrometry with the selected ion recording monitoring was used to detect and quantify the fatty acid.The calibration curves were linear in the range of 10.00–5000 pg/mL for linoleic acid and docosanoic acid,and 1.000–500.0 pg/mL for docosahexaenoic acid.The limit of detection was 2.0 pg/mL for linoleic acid,3.0 pg/mL for docosanoic acid,and 0.20 pg/mL for docosahexaenoic acid.The results showed that the method described in this paper could be utilized for rapid determination of three fatty acids at picogram levels in edible oils. | BI Xin JIN YiBao LI ShangFu GAO Dan JIANG YuYang LIU HongXia | 2014 | Science China Chemistry2014，57，3： | 4 |
| 11 | U-shaped association between telomere length and esophageal squamous cell carcinoma risk: a case-control study in Chinese population显示文摘在由维持 chromosomal 正直并且阻止染色体的生物变老的一个关键角色结束的 Telomeres 玩熔化。流行病学的研究建议了 telomere 长度的内部个人的差别能影响倾向到多重癌症,但是关于食道的有鳞的房间癌(ESCC ) 的证据仍然是不明确的。几 telomere 在白种人的长度相关的单个核苷酸多型性(TLSNP ) 在染色体宽的协会研究被报导了。然而,在 ESCC 开发的 telomere 长度和 TL-SNPs 的效果是不清楚的。因此,我们进行了盒子控制研究(1045 个 ESCC 案例和 1433 控制) 在中国人口评估在 telomere 长度, TL-SNPs,和 ESCC 风险之间的协会。作为结果, ESCC 案例显示出全面更短的相对 telomere 长度(RTL )( 中部:1.34 ) 比控制(中部:1.50, P < 0.001 ) 。更有趣地,一个明显的非线性的U字形的协会在 RTL 和 ESCC 风险之间被观察( P < 0.001 )与比率(95%信心间隔)等于到 2.40 的机会( 1.843.14 ), 1.36 ( 1.031.79 ), 1.01 ( 0.761.35 ),并且 1.37 ( 1.031.82 )为个人在第一(最短),第二,第三,并且 第5 (最长) quintile 分别地,在是的 第4 quintile 与那些相比引用组。没有重要协会在八报导 TL-SNPs 和 ESCC 危险性之间被观察。这些调查结果建议短或极其长的 telomeres 可以是为在中国人口的 ESCC 的风险因素。 | Jiangbo Du Wenjie Xue Yong Ji Xun Zhu Yayun Gu Meng Zhu Cheng Wang Yong Gao Juncheng Dai Hongxia Ma Yue Jiang Jiaping Chen Zhibin Hu Guangfu Jin Hongbing Shen | 2015 | Frontiers of Medicine2015，9，4： | 4 |
| 12 | Oxygen Isotope Clue to Migration of Dolomitizing Fluid as Exampled by the Changxing Formation Dolomite at Panlongdong, Northeastern Sichuan显示文摘The Upper Permian Changxing dolomite reservoirs serves as one of the most important gas and oil reservoirs in the NE Sichuan Basin. Determining the dolomitizing fluid's pathway is regarded as the key to solve the 'dolomite problem' and further petroleum exploration. Outcrop samples from Upper Permian Changhsingian Panlongdong Section were studied using oxygen isotopic analysis, cathodoluminescence(CL) and major element analysis, in an attempt to determine the migration path way and properties of the dolomitizing fluid. Of the Changxing dolomite, the δ18O values ranged from-3.494‰ to-5.481‰, which decreased from the top layer to the bottom in the section; the MgO contents varied from 9.24% to 21.43%, CaO contents from 28.65% to 39.87%, the CaO/MgO ratio from 1.40 to 4.31 and the Mn O contents from 0.004% to 0.009 8%. The Mg O contents showed a downwardly decreasing trend in the section, while the Ca O/Mg O showed an opposite rule. All of the dolomites looked dull or dark when they were exposed to the electron beam of the cathodoluminescence device. None of the fine-to medium grained dolomite showed a banded structure. Given that dolomitizing fluid's salinity decreased during the dolomitization process in its pathway, we concluded that the dolomitizing fluid migrated downwardly in Changxing Formation after excluding the possibility of deep burial or meteoric-marine mixing-water influences. As the dolomitizing fluid's pathway has always been difficult to be determined in highly dolomitized Formation, this study showed an important application of oxygen isotope values in resolving this problem. | Rui Zhao Yasheng Wu Hongxia Jiang Qingsong Liu 无 | 2017 | Journal of Earth Science2017，28，2： | 4 |
| 13 | Diagenesis of the microbialites in the Permian-Triassic boundary section at Laolongdong,Chongqing,South China显示文摘An interval of limestone,which generally has a dendroid appearance on outcrops,has been found in several Permian-Triassic boundary(PTB) sections in South China,and interpreted to be microbialites.Previous research has examined the paleontology and sedimentology of the unit,however,little attention has been devoted to its diagenesis.This paper discusses the diagenesis of the microbialites in the PTB section at Laolongdong,Chongqing,South China.Examination of multiple outcrops reveals that the structure in this kind of rock is not always dendroid;in many cases it is irregular in shape,and seldom shows the 'up-branching' form.In addition,the speckled interval has also been found beneath the dendroid interval.In outcrop,both the speckled and dendroid rocks consist of the darkercolored areas and the lighter-colored areas.Examination of thin sections reveals that the darker-colored areas on outcrops are actually lighter-colored in thin sections,consist of larger crystals,and are more transparent.The lighter-colored areas in thin sections generally consist of large blocky calcite containing scattered small dirty calcite rhombs and irregular residual limestones,which are the same as the lime mudstones between the lighter-colored areas.It is inferred that the dendroid and speckled rocks have experienced the following diagenetic processes:(1) exposure of the carbonate sediments to the subaerial environment because of a sea level drop;(2) dolomitization caused by the downward migration of fluids formed the dendroid and speckled dolomitic patches;(3) dedolomitization of the dolomitic patches formed dendroid and speckled patches of calcite;(4) dissolution occurred in the interstices between relic dolomite crystals formed spongy pores;and(5) filling of the spongy pores by large blocky calcite.Therefore,even though microbes played a critical role in the formation of these microbialites,diagenesis contributed greatly to the formation of the speckled and dendroid pattern of the microbialites. | Jiang Hongxia Wu Yasheng | 2013 | Journal of Palaeogeography2013，2，2： | 4 |
| 14 | Bortezomib improves progression-free survival in multiple myeloma patients overexpressing preferentially expressed antigen of melanoma显示文摘 | Qin Yazhen Lu Jin Bao Li Zhu Honghu Li Jinlan Li Lingdi Lai Yueyun Shi Hongxia Wang Yazhe Liu Yanrong Jiang Bin Huang Xiaojun | 2014 | Chinese Medical Journal2014，，9： | 4 |
| 15 | Effect of Alkylaluminum Activators on Ethylene Trimerization Based on 2,5-DMP/Cr(III)/TCE Catalyst System显示文摘向 1-hexene 的乙烯 trimerization 有 2,5-dimethylpyrrole (2,5-DMP ) 的催化系统 /Cr (III )/alkylaluminum/tetrachloroethane (TCE ) 被调查。在催化活动和产品选择的各种各样的 cocatalysts 的效果被讨论。结果证明 triethylaluminum (茶) , trimethylaluminum (TMA ) , tri-n-hexylaluminum (TNHA ) 和 tri-isobutylaluminum (TIBA ) 都是为向 1-hexene 的乙烯 trimerization 的有效 cocatalysts。2,5-DMP/Cr (III )/TEA/TCE 催化系统为乙烯 trimerization 负担得起最好的结果,当减少副产品的水平时形成。有在催化周期的活跃 Cr 种类的 alkylaluminum 的一些特定的相互作用模式被建议在催化活动和 1-hexene 选择解释 cocatalyst 的效果。 | Jiang, Tao Ji, Rongxin Chen, Hongxia Cao, Chengang Mao, Guoliang Ning, Yingnan | 2011 | Chinese Journal of Chemistry2011，29，6： | 3 |
| 16 | Polymer-derived SiBCN ceramic pressure sensor with excellent sensing performance显示文摘Pressure measurement with excellent stability and long time durability is highly desired,especially at high temperature and harsh environments.A polymer-derived silicoboron carbonitride(SiBCN)ceramic pressure sensor with excellent stability,accuracy,and repeatability is designed based on the giant piezoresistivity of SiBCN ceramics.The SiBCN ceramic sensor was packaged in a stainless steel case and tested using half Wheatstone bridge with the uniaxial pressure up to 10 MPa.The SiBCN ceramic showed a remarkable piezoresistive effect with the gauge factor(K)as high as 5500.The output voltage of packed SiBCN ceramic sensor changes monotonically and smoothly versus external pressure.The as received SiBCN pressure sensor possesses features of short response time,excellent repeatability,stability,sensitivity,and accuracy.Taking the excellent high temperature thermo-mechanical properties of polymer-derived SiBCN ceramics(e.g.,high temperature stability,oxidation/corrosion resistance)into account,SiBCN ceramic sensor has significant potential for pressure measurement at high temperature and harsh environments. | Gang SHAO Junpeng JIANG Mingjie JIANG Jie SU Wen LIU Hailong WANG Hongliang XU Hongxia LU Rui ZHANG | 2020 | Journal of Advanced Ceramics2020，9，3： | 3 |
| 17 | Hypoxia-controlled matrix metalloproteinase-9 hyperexpression promotes behavioral recovery after ischemia显示文摘Matrix metalloproteinase-9(MMP-9) plays a beneficial role in the sub-acute phase after ischemic stroke.However,unrestrained MMP-9 may disrupt the blood-brain barrier(BBB),which has limited its use for the treatment of brain ischemia.In the present study,we constructed lentivirus mediated hypoxiacontrolled MMP-9 expression and explored its role after stroke.Hypoxia response element(HRE)was used to confine MMP-9 expression only to the hypoxic region of mouse brain after 120-min transient middle cerebral artery occlusion.Lentiviruses were injected into the peri-infarct area on day 7 after transient ischemia.We found hyperexpression of exogenous HRE-MMP-9 under the control of hypoxia,and its expression was mainly located in neurons and astrocytes without aggravation of BBB damage compared to the CMV group.Furthermore,mice in the HRE-MMP-9 group showed the best behavioral recovery compared with the normal saline,GFP,and SB-3CT groups.Therefore,hypoxia-controlled MMP-9 hyperexpression during the sub-acute phase of ischemia may provide a novel promising approach of gene therapy for stroke. | Hongxia Cai Zhihao Mu Zhen Jiang Yongting Wang Guo-Yuan Yang Zhijun Zhang | 2015 | Neuroscience Bulletin2015，31，5： | 3 |
| 18 | Hydrochemical characteristics and water quality evaluation of shallow groundwater in Suxian mining area,Huaibei coalfield,China显示文摘The aim of this study is to evaluate the hydrogeochemical characteristics and water environmental quality of shallow groundwater in the Suxian mining area of Huaibei coalfield,China.The natural formation process of shallow groundwater in Suxian is explored using Piper trilinear charts and Gibbs diagrams,and by examining the ratios between the major ions.United States Salinity Laboratory(USSL)charts,Wilcox diagrams,and the water quality index(WQI)are further employed to quantify the differences in water quality.The results reveal that the main hydrochemical facies of groundwater are HC03-Ca,and that silicate dissolution is the main factor controlling the ion content in shallow groundwater.The USSL charts and Wilcox diagrams show that most of the water samples would be acceptable for use in irrigation systems.The WQI results for each water sample are compared and analyzed,and the quality of groundwater samples around collapse ponds is found to be relatively poor. | Hao Yu Herong Gui Honghai Zhao Meichen Wang Jun Li Hongxia Fang Yaqi Jiang Yaru Zhang | 2020 | International Journal of Coal Science & Technology2020，7，4： | 3 |
| 19 | Construction of hydrangea-like core-shell SiO_(2)@Ti_(3)C_(2)T_(x)@CoNi microspheres for tunable electromagnetic wave absorbers显示文摘Ti_(3)C_(2)T_(x)MXene shows great potential in the application as microwave absorbers due to its high attenuation ability.However,excessively high permittivity and self-stacking are the main obstacles that constrain its wide range of applications.To tackle these problems,herein,the microspheres of SiO_(2)@Ti_(3)C_(2)T_(x)@CoNi with the hydrangea-like core-shell structure were designed and prepared by a combinatorial electrostatic assembly and hydrothermal reaction method.These microspheres are constructed by an outside layer of CoNi nanosheets and intermediate Ti_(3)C_(2)T_(x)MXene nanosheets wrapping on the core of modified SiO_(2),engendering both homogenous and heterogeneous interfaces.Such trilayer SiO_(2)@Ti_(3)C_(2)T_(x)@CoNi microspheres are“magnetic microsize supercapacitors”that can not only induce dielectric loss and magnetic loss but also provide multilayer interfaces to enhance the interfacial polarization.The optimized impedance matching and core-shell structure could boost the reflection loss(RL)by electromagnetic synergy.The synthesized SiO_(2)@Ti_(3)C_(2)T_(x)@CoNi microspheres demonstrate outstanding microwave absorption(MA)performance benefited from these advantages.The obtained RL value was-63.95 dB at an ultra-thin thickness of 1.2 mm,corresponding to an effective absorption bandwidth(EAB)of 4.56 GHz.This work demonstrates that the trilayer core-shell structure designing strategy is highly efficient for tuning the MA performance of MXene-based microspheres. | Huanhuan Niu Xuewen Jiang Yongde Xia Hailong Wang Rui Zhang Hongxia Li Bingbing Fan Yanchun Zhoua | 2023 | Journal of Advanced Ceramics2023，12，4： | 3 |
| 20 | Association of assisted reproductive technology, germline de novo mutations and congenital heart defects in a prospective birth cohort study显示文摘Emerging evidence suggests that children conceived through assisted reproductive technology(ART)have a higher risk of congenital heart defects(CHDs)even when there is no family history.De novo mutation(DNM)is a well-known cause of sporadic congenital diseases;however,whether ART procedures increase the number of germline DNM(gDNM)has not yet been well studied.Here,we performed whole-genome sequencing of 1137 individuals from 160 families conceived through ART and 205 families conceived spontaneously.Children conceived via ART carried 4.59 more gDNMs than children conceived spontaneously,including 332 paternal and 1.26 maternal DNMs,after correcting for parental age at conception,cigarette smoking,alcohol drinking,and exercise behaviors.Paternal DNMs in offspring conceived via ART are characterized by C>T substitutions at CpG sites,which potentially affect protein-coding genes and are significantly associated with the increased risk of CHD.In addition,the accumulation of non-coding functional mutations was independently associated with CHD and 87.9% of the mutations were originated from the father.Among ART offspring,infertility of the father was associated with elevated paternal DNMs;usage of both recombinant and urinary follicle-stimulating hormone and high-dosage human chorionic gonadotropin trigger was associated with an increase of maternal DNMs.In sum,the increased gDNMs in offspring conceived by ART were primarily originated from fathers,indicating that ART itself may not be a major reason for the accumulation of gDNMs.Our findings emphasize the importance of evaluating the germline status of the fathers in families with the use of ART. | Cheng Wang Hong Lv Xiufeng Ling Hong Li Feiyang Diao Juncheng Dai Jiangbo Du Ting Chen Qi Xi Yang Zhao Kun Zhou Bo Xu Xiumei Han Xiaoyu Liu Meijuan Peng Congcong Chen Shiyao Tao Lei Huang Cong Liu Mingyang Wen Yangqian Jiang Tao Jiang Chuncheng Lu Wei Wu Di Wu Minjian Chen Yuan Lin Xuejiang Guo Ran Huo Jiayin Liu Hongxia Ma Guangfu Jin Yankai Xia Jiahao Sha Hongbing Shen Zhibin Hu | 2021 | Cell Research2021，31，8： | 2 |
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