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| 1 | Herbal decoctosome is a novel form of medicine显示文摘Traditionally, herbal medicine is consumed by drinking decoctions produced by boiling herbs with water. The functional components of the decoction are heat stable. Small RNAs(sRNAs) were reported as a new class of functional components in decoctions. However, the mechanisms by which sRNAs survive heat treatment of the decoction and enter cells are unclear.Previous studies showed that plant-derived exosome-like nanoparticles(ELNs), which we call botanosomes, could deliver therapeutic reagents in vivo. Here, we report that heat-stable decoctosomes(ELNs) from decoctions have more therapeutic effects than the decoctions in vitro and demonstrate therapeutic efficacy in vivo. Furthermore, sRNAs, such as HJT-sRNA-m7 and PGY-sRNA-6, in the decoctosome exhibit potent anti-fibrosis and anti-inflammatory effects, respectively. Decoctosome is comprised of lipids, chemical compounds, proteins, and s RNAs. A medical decoctosome mimic is called bencaosome. A single lipid sphinganine(d22:0) identified in the decoctosome was mixed and heated with the synthesized sRNAs to form the simplest bencaosome. This simple bencaosome structure was identified by critical micelle concentration(cmc) assay that sRNAs coassembled with sphinganine(d22:0) to form the lipid layers of vesicles. The heating process facilitates co-assembly of sRNAs and sphinganine(d22:0) until a steady state is reached. The artificially produced sphinganine-HJT-sRNA-m7 and sphinganinePGY-sRNA-6 bencaosomes could ameliorate bleomycin-induced lung fibrosis and poly(I:C)-induced lung inflammation, respectively, following oral administration in mice. Our study not only demonstrates that the herbal decoctosome may represent a combinatory remedy in precision medicine but also provides an effective oral delivery route for nucleic acid therapy. | Xiaoyun Li Zhu Liang Jianchao Du Zhiqing Wang Song Mei Zhiqing Li Yan Zhao DANDan Zhao Yiming Ma Jun Ye Jiantao Xu Yu Zhao Jiahui Chang Yuhao Qin Lanlan Yu Chenxuan Wang Chengyu Jiang | 2019 | Science China(Life Sciences)2019，62，3： | 26 |
| 2 | Visualization of CO_2 and oil immiscible and miscible flow processes in porous media using NMR micro-imaging显示文摘CO_2 flooding is considered not only one of the most effective enhanced oil recovery(EOR) methods,but also an important alternative for geological CO_2 storage.In this paper,the visualization of CO_2 flooding was studied using a 400 MHz NMR micro-imaging system.For gaseous CO_2 immiscible displacement,it was found that CO_2 channeling or fingering occurred due to the difference of fluid viscosity and density.Thus,the sweep efficiency was small and the final residual oil saturation was 53.1%.For supercritical CO_2 miscible displacement,the results showed that piston-like displacement occurred,viscous fingering and the gravity override caused by the low viscosity and density of the gas was effectively restrained,and the velocity of CO_2 front was uniform.The sweep efficiency was so high that the final residual oil saturation was 33.9%,which indicated CO_2 miscible displacement could enhance oil recovery more than CO_2 immiscible displacement.In addition,the average velocity of CO_2 front was evaluated through analyzing the oil saturation prof ile.A special core analysis method has been applied to in-situ oil saturation data to directly evaluate the local Darcy phase velocities and capillary dispersion rate. | Zhao Yuechao SongYongchen Liu Yu Jiang Lanlan Zhu Ningjun | 2011 | Petroleum Science2011，8，2： | 9 |
| 3 | Dissociation characteristics of methane hydrate using depressurization combined with thermal stimulation显示文摘Methane hydrate is considered as a potential energy source in the future due to its abundant reserves and high energy density.To investigate the influence of initial hydrate saturation,production pressure,and the temperature of thermal stimulation on gas production rate and cumulative gas production percentage,we conducted the methane hydrate dissociation experiments using depressurization,thermal stimulation and a combination of two methods in this study.It is found that when the gas production pressures are the same,the higher the hydrate initial saturation,the greater change in hydrate reservoir temperature.Therefore,it is easier to appear the phenomenon of icing and hydrate reformation when the hydrate saturation is higher.For example,the reservoir temperature dropped to below zero in depressurization process when the hydrate saturation was about 37%.However,the same phenomenon didn’t appear as the saturation was about 12%.This may be due to more free gas in the reservoir with hydrate saturated of 37%.We also find that the temperature variation of reservoir can be reduced effectively by combination of depressurization and thermal stimulation method.And the average gas production rate is highest with combined method in the experiments.When the pressure of gas production is 2 MPa,compared with depressurization,the average of gas production can increase 54%when the combined method is used.The efficiency of gas production is very low when thermal stimulation was used alone.When the temperature of thermal stimulation is 11℃,the average rate of gas production in the experiment of thermal stimulation is less than 1/3 of that in the experiment of the combined method. | Mingjun Yang Zhanquan Ma Yi Gao Lanlan Jiang | 2019 | Chinese Journal of Chemical Engineering2019，27，9： | 5 |
| 4 | Fe3C-N-doped carbon modified separator for high performance lithium-sulfur batteries显示文摘A new Fe3C-N-doped reduced graphene oxide(Fe3C-N-rGO)prepared by a facile method is used as a separator for high performance lithium-sulfur(Li-S)batteries.The Fe3C-N-rGO is coated on the surface of commercial polypropylene separator(Celgard 2400)close to the sulfur cathode.The special nanotubes are in-situ catalyzed by Fe3C nanoparticles.They could entrap lithium polysulfides(Li PSs)to restrain the shuttle effect and reduce the loss of active material.The battery with the modified separator and sulfur cathode shows an excellent cycle performance.It has a high rate performance,580.5 mAh/g at the high current rate of 4 C relative to 1075 mAh/g at 0.1 C.It also has an initial discharge capacity of 774.8 m Ah/g measured at 0.5 C and remains 721.8 mAh/g after 100 cycles with a high capacity retention of 93.2%.The outstanding performances are notable in recently reports with modified separator. | Hongyu Pan Zhong Tan Haihui Zhou Lanlan Jiang Zhongyuan Huang Qjaoxia Feng Qiang Zhou Shuai Ma Yafei Kuang | 2019 | Journal of Energy Chemistry2019，28，12： | 5 |
| 5 | Erratum to:Herbal decoctosome is a novel form of medicine显示文摘Following the published article,we noticed an error duplication in Figure 5G“control”and“PGY-6”that was introduced during the revised process,with an attempt to replace it with higher-resolution images.Here we provide the original data in the first submitted manuscript(Figure 5G). | Xiaoyun Li Zhu Liang Jianchao Du Zhiqing Wang Song Mei Zhiqing Li Yan Zhao Dandan Zhao Yiming Ma Jun Ye Jiantao Xu Yu Zhao Jiahui Chang Yuhao Qin Lanlan Yu Chenxuan Wang Chengyu Jiang | 2020 | Science China(Life Sciences)2020，63，9： | 2 |
| 6 | Adsorption isotherms and kinetic characteristics of methane on block anthracite over a wide pressure range显示文摘It is important to quantitatively understand the methane adsorption and transport mechanism in coal for an evaluation of the reserves and for its production forecast. In this work, a block coal sample was chosen to perform the CH4 adsorption experiments using the gravimetric method at temperatures of 293.60 K, 311.26 K, 332.98 K and 352.55 K and pressures up to 19 MPa. The excess adsorption capacity of CH4 in dry block anthracite increased, followed by a sequence decrease with the increasing pressure. High temperature restrained the growth of the excess adsorption due to that the adsorption is an intrinsically physical and exothermic process. The excess adsorption peak decreased slowly with the increase of temperature and intersected at a pressure of more than 18 MPa; meanwhile, the pressure at the excess adsorption peak increased.The existing correlations were examined in terms of density rather than pressure. The DR+k correlation, with an average relative deviation of ±0.51%, fitted our data better than the others, with an average relative deviation of up to 2.29%. The transportation characteristics of CH4 adsorption was also investigated in this study, including the adsorption rate and diffusion in block coal. The kinetic data could be described by a modified unipore model. The adsorption rates were found to exhibit dependence on pressure and temperature at low pressures, while the calculated diffusivities exhibited little temperature dependence. In addition, the kinetic characteristics were compared between CH4 and CO2 adsorption on the block coal. The excess adsorption ratios of CO2 to CH4obtained from the DR+k model decreased with the increasing pressure. | Wanli Xing Yongchen Song Yi Zhang Weiguo Liu Lanlan Jiang Yanghui Li Yuechao Zhao | 2015 | Journal of Energy Chemistry2015，24，2： | 2 |
| 7 | High-resolution characterization of hexagonal boron nitride coatings exposed to aqueous and air oxidative environments显示文摘六角形的硼氮化物(h-BN ) 被相信由于它的绝缘的性质比 graphene 把更好的钝化提供给金属性的表面,它便于堵住电子的流动,从而阻止流电的反应的出现。不过,当 h-BN-protected 材料暴露于水的环境时,这不能是盒子。在这个工作,我们分析了暴露于 H 2 O 2 和大气的条件。当暴露了到 H 2 O 2 。多层的 h-BN 提供了保护的好度。单层 h-BN 被发现也在空气气氛无效。甚至 10-15 层厚的 h-BN 栈不能完全在考虑下面保护金属的表面。由联合钻电子光谱学和第二等的离子团 spectrometry 技术,我们观察到氧能通过 h-BN 栈的谷物边界扩散到达金属性的底层。因为这个过程的散开的性质,一旦一个浸透的状态被到达,幸好,氧化区域没与时间增加。这成为多层(不单层) h-BN 一个合适的长期的氧化障碍。氧渗入不能被 X 光检查光电子光谱学观察。这种技术不能估计材料的更深的层的化学作文。因此,以前的报告,依靠了 XPS 分析 h-BN 和 graphene 的使钝化的性质,可能忽略了一些重要表面下的现象。在这研究获得的结果在水的媒介和暴露于空气环境的 h-BN-coated 金属的降级动力学提供新卓见进单音、多层的 h-BN 的使钝化的性质。 | Lanlan Jiang Na Xiao Bingru Wang Enric Grustan-Gutierrez Xu Jing Petr Babor Miroslav Kogbal Guangyuan Lu Tianru Wu Haomin Wang Fei Hui Yuanyuan Shi Bo Song Xiaoming Xie Mario Lanza | 2017 | Nano Research2017，10，6： | 2 |
| 8 | Simultaneous Determination of Aflatoxin B 1 and Aflatoxin M 1 in Food Matrices by Enzyme-Linked Immunosorbent Assay显示文摘 | Wenxiao Jiang Zhanhui Wang Greta N?lke Jing Zhang Lanlan Niu Jianzhong Shen | 2013 | Food Analytical Methods2013，，3： | 1 |
| 9 | The effectsof calcite and montmorillonite on oil cracking in confined py-rolysis experiments显示文摘 | Pan Changchun Jiang Lanlan Liu Jinzhong | 2010 | Original Research Article OrganicGeochemistry2010，41，7： | 1 |
| 10 | Simultaneous determination of chloramphenicol, florfenicol and florfenicol amine in ham sausage with a hybrid chemiluminescent immunoassay显示文摘 | Xiaoqi Tao Haiyang Jiang Xuezhi Yu Jinghui Zhu Xia Wang Zhanhui Wang Lanlan Niu Xiaoping Wu Jianzhong Shen | 2013 | Food Additives & Contaminants: Part A2013，，5： | 1 |
| 11 | Effect of aqueous electrolytes on the electrochemical behaviors of supercapacitors based on hierarchically porous carbons显示文摘 | Xiaoyan Zhang Xianyou Wang Lanlan Jiang Hao Wu Chun Wu Jingcang Su | 2012 | Journal of Power Sources2012，，： | 1 |
| 12 | High Order Energy-Preserving Method of the “Good” Boussinesq Equation显示文摘The fourth order average vector field(AVF)method is applied to solve the“Good”Boussinesq equation.The semi-discrete system of the“good”Boussi-nesq equation obtained by the pseudo-spectral method in spatial variable,which is a classical finite dimensional Hamiltonian system,is discretizated by the fourth order average vector field method.Thus,a new high order energy conservation scheme of the“good”Boussinesq equation is obtained.Numerical experiments confirm that the new high order scheme can preserve the discrete energy of the“good”Boussinesq equation exactly and simulate evolution of different solitary waves well. | Chaolong Jiang Jianqiang Sun Xunfeng He Lanlan Zhou | 2016 | Numerical Mathematics(Theory,Methods and Applications)2016，9，1： | 1 |
| 13 | Molecular correlation of crude oils and oil components from reservoir rocks in the Tazhong and Tabei uplifts of the Tarim Basin, China 显示文摘 | Yu Shuang Pan Changchun Wang Jinji Jin Xiaodong Jiang Lanlan Liu Dayong LiJ Xiuxiang Qin Jianzhong Qian Yixiong Ding Yong Chen | 2011 | Org Geochem2011，42，10： | 1 |
| 14 | The effects of calcite and montmorillonite on oil cracking in confined pyrolysis experiments显示文摘 | Changchun Pan Lanlan Jiang Jinzhong Liu Shuichang Zhang Guangyou Zhu | 2010 | Organic Geochemistry2010，，7： | 1 |
| 15 | The effects of calcite and montmorillonite on oil cracking in confined pyrolysis experiments显示文摘 | Pan Changchun Jiang Lanlan Liu Jinzhong | 2010 | Organic Geochemistry2010，41，7： | 1 |
| 16 | The ef-fects of calcite and montmorillonite on oil cracking in con-fined pyrolysis experiments显示文摘 | Pan Changchun Jiang Lanlan Liu Jinzhong | | 0，，： | 1 |
| 17 | The effects of pyrobitumen on oil cracking in confined pyrolysis experiments显示文摘 | Changchun Pan Lanlan Jiang Jinzhong Liu Shuichang Zhang Guangyou Zhu | 2012 | Organic Geochemistry2012，，： | 1 |
| 18 | The effects of calcite and montmorillonite on oil cracking in confined pyrolysis experiments显示文摘 | Changchun Pan Lanlan Jiang Jinzhong Liu Shuichang Zhang Guangyou Zhu | 2010 | Organic Geochemistry2010，，： | 1 |
| 19 | Microclimate Effect of Artificial Caragana microphylla Communities in Horqin Sandy Land显示文摘Caragana microphylla is one of the key species for vegetation restoration in Horqin Sandy Land. Adopting field investigation and outdoor experiments,the microclimate effect of artificial C. microphylla communities with different restoration years were studied by observing wind velocity,air temperature,relative humidity and soil temperature. The results show that:( 1) Caragana microphylla community has an obvious wind-breaking effect near ground surface. Compared with shifting dunes,the wind velocity in the 6-year-old and 11-year-old C. microphylla shrubs at the height of 30 cm separately decreases by 71. 9% and 76. 0%.( 2) Mean daily temperature in the 6-year-old and 11-yearold C. microphylla communities is 3. 7 ℃ and 4. 9 ℃ lower than in shifting dunes,respectively.( 3) The relative humidity of air in the Caragana microphylla shrubs is higher than in shifting dunes.( 4) Soil temperature in C. microphylla plantation is lower than in shifting dunes. These results are significant in further exploring material and energy exchange near surface layer of artificial vegetation in the extremely arid condition. | Shanfeng HE Lanlan QIU Deming JIANG Yongming LUO | 2014 | Asian Agricultural Research2014，6，5： | 0 |
| 20 | Quantitative Seismicity Analysis for the Risk of Historical Large Earthquake Rupture Zone:Application to the Mid-North Segment of the North-South Seismic Belt显示文摘Although seismic gap theory plays an important role in the med-and long-term earthquake prediction,the potential risk of the non-seismic gap in historical earthquake rupture areas will need to be simultaneously taken into account in the study of med-and long-term earthquake prediction,due to the temporally clustering or non-linear behavior of large earthquake recurrence.In order to explore technical methods which can be based on observational data,and identify historical earthquake rupture zones( including the seismic gap in historical and prehistoric earthquake rupture zones),we select eight historical large earthquake rupture zones with different elapsed times on the mid-north segment of the North-South Seismic Belt to make quantitative analysis on the characteristics of modern seismicity of these zones and preliminarily explore the seismicity method for determining the urgency degree of potential earthquake hazards.The results mainly show that the pvalue,which reflects the attenuation of earthquake sequence,and the a-value,which reflects the seismicity rate,are strongly related to the elapsed time of the latest earthquake in the rupture zone.However,the corresponding relationships in some rupture areas are not clear perhaps due to the complex fault structure and faulting behavior.The b-value,which represents the state of tectonic stress accumulation,does not easily reflect the elapsed time information of different evolution stages.The b-value temporal scanning shows a steady evolution over time in most of the rupture zones,but in the rupture zone of the Wudu M8.0 earthquake of 1879,the b-value shows significant fluctuations with a decreasing trend for 20 years.By comparative analysis,we conclude that the rupture zones of the 1933 M7.5 Maoxian earthquake and the 1976 M7.2 Songpan-Pingwu earthquake are still in the decaying period of earthquake sequences,and thus do not have the background for recurrence of M7.0 earthquakes.The low b-value Maqu segment,which is located at the north margin of the rupture zone of the 842A.D.M7.0 Diebu earthquake,is more dangerous than the Diebu segment.The continuous decline of the b-value in the 1879 M8.0 Wudu earthquake rupture zone may also indicate a new round of seismogenic process. | Long Feng Jiang Changsheng Feng Jiangang Tang Lanlan | 2013 | Earthquake Research in China2013，27，3： | 0 |
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