|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Broadband mid-infrared supercontinuum generation in dispersion-engineered As_(2)S_(3)-silica nanospike waveguides pumped by 2.8 μm femtosecond laser显示文摘Broadband mid-infrared(IR)supercontinuum laser sources are essential for spectroscopy in the molecular fingerprint region.Here,we report generation of octave-spanning and coherent mid-IR supercontinua in As_(2)S_(3)-silica nanospike hybrid waveguides pumped by a custom-built 2.8μm femtosecond fiber laser.The waveguides are formed by pressure-assisted melt-filling of molten As_(2)S_(3) into silica capillaries,allowing the dispersion and nonlinearity to be precisely tailored.Continuous coherent spectra spanning from 1.1μm to 4.8μm(30 dB level)are observed when the waveguide is designed so that 2.8μm lies in the anomalous dispersion regime.Moreover,linearly tapered millimeter-scale As_(2)S_(3)-silica waveguides are fabricated and investigated for the first time,to the best of our knowledge,showing much broader supercontinua than uniform waveguides,with improved spectral coherence.The waveguides are demonstrated to be long-term stable and water-resistant due to the shielding of the As_(2)S_(3) by the fused silica sheath.They offer an alternative route to generating broadband mid-IR supercontinua,with applications in frequency metrology and molecular spectroscopy,especially in humid and aqueous environments. | Pan Wang Jiapeng Huang Shangran Xie Johann Troles and Philip St.J.Russell | 2021 | Photonics Research2021，9，4： | 4 |
| 2 | Enhanced production of seed oil with improved fatty acid composition by overexpressing NAD^(+)-dependent glycerol-3-phosphate dehydrogenase in soybean显示文摘There is growing interest in expanding the production of soybean oils(mainly triacylglycerol, or TAG) to meet rising feed demand and address global energy concerns. We report that a plastidlocalized glycerol-3-phosphate dehydrogenase(GPDH), encoded by GmGPDHp1 gene, catalyzes the formation of glycerol-3-phosphate(G3 P), an obligate substrate required for TAG biosynthesis.Overexpression of GmGPDHp1 increases soybean seed oil content with high levels of unsaturated fatty acids(FAs), especially oleic acid(C18:1), without detectably affecting growth or seed protein content or seed weight. Based on the lipidomic analyses, we found that the increase in G3 P content led to an elevated diacylglycerol(DAG) pool, in which the Kennedy pathwayderived DAG was mostly increased, followed by PC-derived DAG, thereby promoting the synthesis of TAG containing relatively high proportion of C18:1. The increased G3 P levels induced several transcriptional alterations of genes involved in the glycerolipid pathways. In particular, genes encoding the enzymes responsible for de novo glycerolipid synthesis were largely upregulated in the transgenic lines, in-line with the identified biochemical phenotype. These results reveal a key role for GmGPDHp1-mediated G3 P metabolism in enhancing TAG synthesis and demonstrate a strategy to modify the FA compositions of soybean oils for improved nutrition and biofuel. | Ying Zhao Pan Cao Yifan Cui Dongxu Liu Jiapeng Li Yabin Zhao Siqi Yang Bo Zhang Runnan Zhou Minghao Sun Xuetian Guo Mingliang Yang Dawei Xin Zhanguo Zhang Xin Li Chen Lv Chunyan Liu Zhaoming Qi Jingyu Xu Xiaoxia Wu Qingshan Chen | 2021 | Journal of Integrative Plant Biology2021，63，6： | 4 |
| 3 | Preliminary investigations into surface molecularly imprinted nanoparticles for Helicobacter pylori eradication显示文摘This paper reports investigations into the preparation and characterization of surface molecularly imprinted nanoparticles(SMINs) designed to adhere to Helicobacter pylori(H.pylori).Imprinted nanoparticles were prepared by the inverse microemulsion polymerization method.A fraction of Lpp20,an outer membrane protein of H.pylori known as NQA,was chosen as template and modified with myristic acid to facilitate its localization on the surface of the nanoparticles.The interaction between these SMINs with the template NQA were evaluated using surface plasmon resonance(SPR),change in zeta potential and fluorescence polarization(FP).The results were highly consistent in demonstrating a preferential recognition of the template NQA for SMINs compared with the control nanoparticles.In vitro experiments also indicate that such SMINs are able to adhere to H.pylori and may be useful for H.pylori eradication. | Jiaying Han Yinjing Sun Jiapeng Hou Yuyan Wang Yu Liu Cao Xie Weiyue Lu Jun Pan | 2015 | Acta Pharmaceutica Sinica B2015，5，6： | 2 |
| 4 | Material patterning on substrates by manipulation of fluidic behavior显示文摘Patterned materials on substrates are of great importance for a wide variety of applications.In solution-based approaches to material patterning;fluidic flow is inevitable.Here we demonstrate not only the importance of fluidic behavior but also the methodology of engineering the flow pattern to guide the material crystallization and assembly.We show by both experiment and simulation that substrate heating;which is generally used to accelerate evaporation,produces irregular complex vortexes.Instead;a top-heating-bottom-cooling(THBC)set-up offers an inverse temperature gradient and results in a single Marangoni vortex,which is desired for ordered nanomaterial patterning near the contact line.We then realize the fabrication of large-scale patterns of iodide perovskite crystals on different substrates under THBC conditions.We further demonstrate that harnessing the flow behavior is a general strategy with great feasibility to pattern various functional materials ranging from inorganic;organic,hybrid to biological categories on different substrates,presenting great potential for practical applications. | Yitan Li Hao Wang Henglu Xu Shiting Wu Xuemei Li Jiapeng Yu Chaoyu Huang Zeyao Zhang Hao Sun Lu Han Meihui Li Anyuan Cao Zhenhai Pan Yan Li | 2019 | National Science Review2019，6，4： | 0 |
| 5 | Advanced ocean wave energy harvesting:current progress and future trends显示文摘With a transition towards clean and low-carbon renewable energy,against the backdrop of the fossil-energy crisis and rising pollution,ocean energy has been proposed as a significant possibility for mitigating climate change and energy shortages for its characteristics of clean,renewable,and abundant.The rapid development of energy harvesting technology has led to extensive applications of ocean wave energy,which,however,has faced certain challenges due to the low-frequency and unstable nature of ocean waves.This paper overviews the debut and development of ocean wave energy harvesting technology,and discusses the potential and application paradigm for energy harvesting in the“intelligent ocean.”We first describe for readers the mechanisms and applications of traditional wave energy converters,and then discuss current challenges in energy harvesting performance connected to the characteristics of ocean waves.Next,we summarize the progress in wave energy harvesting with a focus on advanced technologies(e.g.,data-driven design and optimization)and multifunctional energy materials(e.g.,triboelectric metamaterials),and finally propose recommendations for future development. | Fang HE Yibei LIU Jiapeng PAN Xinghong YE Pengcheng JIAO | 2023 | Journal of Zhejiang University-Science A(Applied Physics & Engineering)2023，24，2： | 0 |
| 6 | [(CH_(3))_(4)N]_(2)Mn_(0.6)Zn_(0.4)Br_(4):Lead-free MnII-based hybrid halide with high photoluminescence quantum yield for backlight displays显示文摘High efficient lead halide perovskites with wide-color gamut properties have emerged as new candidates for backlight displays.However,the toxicity of lead and the instability of halide perovskites greatly limit their practical applications.Herein,the luminescent powders of[(CH_(3))4N]2MnBr_(4)and[(CH_(3))4N]MnBr3 were synthesized via a simple yet robust solvent evaporation method.[(CH_(3))4N]2MnBr_(4)with tetrahedral coordination Mn^(2+)and[(CH_(3))4N]MnBr3 with octahedral coordination Mn^(2+)show green at 517 nm and red emission peaks at 620 nm,respectively,originating from the^(4)T1-^(6)A_(1)transition of Mn^(2+).To enhance optical of manganese halide via effective alloying,Zn^(2+)-doped[(CH_(3))4N]2MnBr_(4)was successfully prepared,and the quantum efficiency of[(CH_(3))_(4)N]_(2)Mn_(0.6)Zn_(0.4)Br_(4)was as high as 65%.Furthermore,[(CH_(3))4N]2Mn0.6Zn0.4Br_(4)exhibits better optical and thermal stability compared to[(CH_(3))4N]2MnBr_(4).[(CH_(3))_(4)N]_(2)Mn_(0.6)Zn_(0.4)Br_(4)@CsPbBr_(1.2)I_(1.8)light conversion films with different green-to-red ratios are placed in backlight display devices,and their color gamut exceeds 106%of the National Television Standards Committee(NTSC)1953 standard,which is superior to the currently reported Mn-based perovskite.This work broadly shows that the[(CH_(3))_(4)N]_(2)Mn_(0.6)Zn_(0.4)Br_(4)will provide effective route to fabricate stable and high-performance lead-free liquid crystal displays. | Xiaoting Liu Jiapeng Yang Wenya Chen Fan Yang Yihuang Chen Xiaojuan Liang Shuang Pan Weidong Xiang | 2023 | Nano Research2023，16，4： | 0 |
| 7 | Targeting FAPα-positive lymph node metastatic tumor cells suppresses colorectal cancer metastasis显示文摘Lymphatic metastasis is the main metastatic route for colorectal cancer, which increases the risk of cancer recurrence and distant metastasis. The properties of the lymph node metastatic colorectal cancer(LNM-CRC) cells are poorly understood, and effective therapies are still lacking. Here, we found that hypoxia-induced fibroblast activation protein alpha(FAPα) expression in LNM-CRC cells. Gain-or loss-function experiments demonstrated that FAPα enhanced tumor cell migration, invasion, epithelial-mesenchymal transition, stemness, and lymphangiogenesis via activation of the STAT3 pathway. In addition, FAPα in tumor cells induced extracellular matrix remodeling and established an immunosuppressive environment via recruiting regulatory T cells, to promote colorectal cancer lymph node metastasis(CRCLNM). Z-GP-DAVLBH, a FAPα-activated prodrug, inhibited CRCLNM by targeting FAPα-positive LNM-CRC cells. Our study highlights the role of FAPα in tumor cells in CRCLNM and provides a potential therapeutic target and promising strategy for CRCLNM. | Shuran Fan Ming Qi Qi Qi Qun Miao Lijuan Deng Jinghua Pan Shenghui Qiu Jiashuai He Maohua Huang Xiaobo Li Jie Huang Jiapeng Lin Wenyu Lyu Weiqing Deng Yingyin He Xuesong Liu Lvfen Gao Dongmei Zhang Wencai Ye Minfeng Chen | 2024 | Acta Pharmaceutica Sinica B2024，14，2： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员