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| 1 | Current status of diagnosis and treatment of bladder cancer in China-Analyses of Chinese Bladder Cancer Consortium database显示文摘Objective:To investigate current status of diagnosis and treatment of bladder cancer in China.Methods:A database was generated by Chinese Bladder Cancer Consortium(CBCC).From January 2007 to December 2012,14,260 cases from 44 CBCC centers were included.Data of diagnosis,treatment and pathology were collected.Results:The average age was 63.5 year-old and most patients were male(84.3%).The most common histologic types were urothelial carcinoma(91.4%),adenocarcinoma(1.8%),and squamous carcinoma(1.9%).According to 1973 and 2004 WHO grading system,42.0%,41.0%,and 17.0% of patients were grade 1,2,and 3,and 16.0%,48.7%,and 35.3% of patients were papillary urothelial neoplasms of low malignant potential,low,and high grade,respectively.Non-muscle invasive bladder cancer(NMIBC)and muscle invasive bladder cancer(MIBC)were 25.2% and 74.1%,respectively(0.8% not clear).Carcinoma in situ was only 2.4%.Most patients were diagnosed by white-light cystoscopy with biopsy(74.3%).Fluorescence and narrow band imaging cystoscopy had additional detection rate of 1.0% and 4.0%,respectively.Diagnostic transurethral resection(TUR)provided detection rate of 16.9%.Most NMIBCs were treated with TUR(89.2%).After initial TUR,2.6%accepted second TUR,and 45.7%,69.9%,and 58.7% accepted immediate,induced,and maintenance chemotherapy instillation,respectively.Most MIBCs were treated with radical cystectomy(RC,59.7%).Laparoscopic RCs were 35.1%,while open RC 63.4%.Extended and standard pelvic lymph node dissection were 7% and 66%,respectively.Three most common urinary diversions were orthotopic neobladder(44%),ileal conduit(31%),and ureterocutaneostomy(23%).Only 2.3% of patients accepted neo-adjuvant chemotherapy and only 18%of T3 and T4 patients accepted adjuvant chemotherapy.Conclusion:Disease characteristics are similar to international reports,while differences of diagnosis and treatment exist.This study can provide evidences for revisions of the guideline on bladder cancer in China. | Kaiwen Li Tianxin Lin 无 Wei Xue Xin Mu Enci Xu Xu Yang Fubao Chen Guangyong Li Lulin Ma Guoliang Wang Chaozhao Liang Haoqiang Shi Ming Li Mao Tang Xueyi Xue Yisong Lv Yaoliang Deng Chengyang Li Zhiwen Chen Xiaozhou Zhou Fengshuo Jin Xudong Liu Jinxin Wei Lei Shi Xin Gou Weiyang He Liqun Zhou Lin Cai Baiye Jin Guanghou Fu Xiangbo Kong Hongyan Sun Ye Tian Lang Feng Tiejun Pan Yiyi Wu Dongwen Wang Hailong Hao Benkang Shi Yaofeng Zhu Qiang Wei Ping Han Changli Wu Dawei Tian Zhangqun Ye Zheng Liu Zhiping Wang Junqiang Tian Lin Qi Minfeng Chen Wei Li Jinchun Qi Gongxian Wang Longlong Fu Zhaolin Sun Guangheng Luo Zhoujun Shen Zhaowei Zhu Jinchun Xing Zhun Wu Dong Wei Xin Chen Yanqun Na Hongfeng Guo Chunxi Wang Zhihua Lu Chuize Kong Yang Liu Jin Yang Jianyun Hu Xin Gao Jielin Li Changjun Yin Pu Li Shan Chen Zhen Du Jiongming Li Yongji Yan Xu Zhang Shuang Huang Fangjian Zhou Zhiling Zhang Yinghao Sun Shuxiong Zeng Song Cen Jiaquan Zhou Hanzhong Li Jin Wen Jian Huang | 2015 | Asian Journal of Urology2015，2，2： | 21 |
| 2 | Estimation of earthquake losses by using macroeconomic approach显示文摘Most earthquake loss studies use an inventory approach by which the predicted damages in various categories of structures and facilities in a concerned region are estimated and added together to obtain the total estimated. Such an approach requires a detailed inventory database of the structures and facilities in the region, which is not always readily available in many regions of the world. Therefore, an alternative means of estimating earthquake losses is used based on several macroeconomic indices such as the gross domestic product (GDP) and population. Based on the published earthquake loss data during 1980—1995, the relations between GDP and earthquake losses have been formulated empirically for several intensity ranges. The world’s land surface was divided into unit cells with 0.5°×0.5°in size, the GDP of each cell was apportioned based on its population and the GDP and population of the region to which it belongs. The predicted seismic loss of the cell was then estimated from the seismic | Qifu Chen Yong Chen Ling Chen Jie Liu Minfeng Li | 1999 | Chinese Science Bulletin1999，44，3： | 3 |
| 3 | Optimizing the electrolyte salt of aqueous zinc-ion batteries based on a high-performance calcium vanadate hydrate cathode material显示文摘It is urgent to develop high-performance cathode materials for the emerging aqueous zinc-ion batteries with a facile strategy and optimize the related components.Herein,a Ca0.23V2O5·0.95 H2O nanobelt cathode material with a rather large interlayer spacing of 13.0 A is prepared via a one-step hydrothermal approach.The battery with this cathode material and 3 M Zn(CF3SO3)2 electrolyte displays high specific capacity(355.2 mAh g^(-1) at 0.2 A g^(-1)),great rate capability(240.8 mAh g^(-1) at 5 A g^(-1)),and excellent cyclability(97.7% capacity retention over 2000 cycles).Such superior performances are ascribed to fast electrochemical kinetics,outstanding electrode/electrolyte interface stability,and nearly dendrite-free characteristic.Instead,when ZnSO4 or Zn(ClO4)2 is used to replace Zn(CF3SO3)2,the electrochemical performances become much inferior,due to the slow electrochemical kinetics,inhomogeneous Zn stripping/plating process,and the formation of large dendrites and byproducts.This work not only discloses a high-performance cathode material for aqueous zinc-ion batteries but also offers a reference for the choice of electrolyte salt. | Weijun Zhou Minfeng Chen Anran Wang Aixiang Huang Jizhang Chen Xinwu Xu Ching-Ping Wong | 2021 | Journal of Energy Chemistry2021，30，1： | 2 |
| 4 | Factors Affecting Kyphotic Angle Reduction in Osteoporotic Vertebral Compression Fractures with Kyphoplasty显示文摘 | Shen Minjie Wang Heng Chen Guangdong Gan Minfeng Yuan Quan Wang Zhidong Liu Ling Yang Huilin | 2013 | Orthopedics (Online)2013，，4： | 2 |
| 5 | Visualizing large-scale high-dimensional data via hierarchical embedding of KNN graphs显示文摘Visualizing intrinsic structures of high-dimensional data is an essential task in data analysis.Over the past decades,a large number of methods have been proposed.Among all solutions,one promising way for enabling effective visual exploration is to construct a k-nearest neighbor(KNN)graph and visualize the graph in a low-dimensional space.Yet,state-of-the-art methods such as the LargeVis still suffer from two main problems when applied to large-scale data:(1)they may produce unappealing visualizations due to the non-convexity of the cost function;(2)visualizing the KNN graph is still time-consuming.In this work,we propose a novel visualization algorithm that leverages a multilevel representation to achieve a high-quality graph layout and employs a cluster-based approximation scheme to accelerate the KNN graph layout.Experiments on various large-scale datasets indicate that our approach achieves a speedup by a factor of five for KNN graph visualization compared to LargeVis and yields aesthetically pleasing visualization results. | Haiyang Zhu Minfeng Zhu Yingchaojie Feng Deng Cai Yuanzhe Hu Shilong Wu Xiangyang Wu Wei Chen | 2021 | Visual Informatics2021，5，2： | 2 |
| 6 | Ultrathin Zn-free anode based on Ti_(3)C_(2)T_(x) and nanocellulose enabling high-durability aqueous hybrid Zn-Na battery with Zn2+/Na+co-intercalation mechanism显示文摘With low cost and high safety,aqueous zinc-based batteries have received considerable interest.Nevertheless,the excess utilization of zinc metal in the anodes of these batteries reduces energy density and increases costs.Herein,an ultrathin electrode of approximately 6.2μm thick is constructed by coating Ti_(3)C_(2)T_(x)/nanocellulose hybrid onto a stainless steel foil.This electrode is used as the Zn-free anode for aqueous hybrid Zn-Na battery,in which,a concentrated electrolyte is used to improve electrochemical reversibility.The Ti_(3)C_(2)T_(x)/nanocellulose coating is found to improve the electrolyte wettability,facilitate desolvation process of hydrated Zn^(2+) ions,lower nucleation overpotential,improve zinc plating kinetics,guide horizontal zinc plating along the Zn(002)facet,and inhibit parasitic side reactions.It is also found that the Na_(3)V_(2)(PO_(4))_(3) cathode material adopts a highly reversible Zn^(2+)/Na^(+)co-intercalation charge storage mechanism in this system.Thanks to these benefits,the assembled hybrid Zn-Na battery exhibits excellent rate capability,superior cyclability,and good anti-freezing ability.This work provides a new concept of electrode design for electrochemical energy storage. | Hao Chen Weijun Zhou Minfeng Chen Qinghua Tian Xiang Han Jizhang Chen | 2023 | Nano Research2023，16，1： | 1 |
| 7 | Tumor-responsive copper-activated disulfiram for synergetic nanocatalytic tumor therapy显示文摘Exploring alternative biomedical use of traditional drugs in different disease models is highly important as it can reduce the cost of drug development and overcome several critical issues of traditional chemodrugs such as low chemotherapeutic efficiency,severe side effect,and drug resistance.Disulfiram(DSF),a clinically approved alcohol-aversion drug,was recently demonstrated tofeature tumor-growth suppression effect along with the co-administration of Cu^(2+)species,but direct Cu^(2+)administration mode might cause severe toxicity originating from low Cu^(2+)accumulation into the tumor and nonspecific Cu^(2+)distribution-induced cytotoxicity.Based on the intriguing drug-delivery performance of nanoscale metal-organic frameworks(MOFs),we herein construct HKUST nMOFs as the Cu^(2+)self-supplying nanocarriers for efficient delivery of the D SF drug.The mildly acidic condition of tumor microenvironment initially triggered the release of Cu ions from HKUST nMOFs,which further reacted with the encapsulated DSF toform toxic Cu(DDTC)2(activation)for tumor chemotherapy.Especially,during the Cu(DDTC)2 complexation,Cu^(+)species were formed concomitantly,triggering the intratumoral nanocatalytic therapy for the generation of reactive oxygen species to synergistically destroying the tumor cells/tissue.As a result,synergetic tumor-responsive chemotherapy and nanocatalytic therapy are enabled by DSF@HKU ST nanodrugs,as demonstrated by the dominant anticancer efficacy with satisfied biocompatibility both in vitro and in vivo.The present work offers a sophisticated strategy for tumor-responsive nontoxic-to-toxic therapeutic with high biocompatibility. | Hao Chen Xi Li Minfeng Huo Liying Wang Yu Chen Wei Chen Bailiang Wang | 2021 | Nano Research2021，14，1： | 1 |
| 8 | Artificial solid electrolyte interface layer based on sodium titanate hollow microspheres assembled by nanotubes to stabilize zinc metal electrodes显示文摘Recently,aqueous zinc-ion batteries with intrinsic safety,low cost,and environmental benignity have attracted tremendous research interest.However,zinc dendrites,harmful side reactions,and zinc metal corrosion stand in the way.Herein,we use lepidocrocite-type sodium titanate hollow microspheres assembled by nanotubes to constitute an artificial solid electrolyte interface layer on the zinc metal electrode.Thanks to the hierarchical structure with abundant open voids,negative-charged layered framework,low hydrophilicity,electrically insulting nature,and large ionic conductivity,the sodium titanate coating layer can effectively homogenize the electric field,promote the Zn^(2+)ion transfer,guide the Zn^(2+)ion flux,reduce the desolvation barrier,improve the exchange current density,and accommodate the plated zinc metal.Consequently,this coating layer can effectively suppress zinc dendrites and other unfavorable effects.With this coating layer,the Zn//Zn symmetric cell is able to provide an impressive cumulative zinc plating capacity of 1375 m Ah cm^(-2) at a current density of 5 m A cm^(-2).This coating layer also contributes to significantly improved electrochemical performances of Zn//MnO_(2) battery and zincion hybrid capacitor.This work offers new insights into the modifications of zinc metal electrodes. | Minfeng Chen Weijun Zhou Qinghua Tian Xiang Han Yanjun Tan Jizhang Chen Ching-Ping Wong | 2022 | Journal of Energy Chemistry2022，31，8： | 1 |
| 9 | A simplified approach to the global seismic hazard assessment显示文摘Some earthquakes in recent years (such as Tangshan earthquake (1976, China), North Ridge earthquake (1994, USA), Kobe earthquake (1995, Japan)) did not occur in known faults;moreover, the detailed data of geology, earthquake, crust deformation, etc. needed by the fault model are very difficult to obtain in many regions of the world. A simplified method of global seismic hazard analysis is developed, based on an area source model and by using seismicity data, and the global seismic hazard map is compiled. To evaluate the effectiveness and credibility of the new method, comparison study of this map with the existing national maps has been performed, which implies that it is considerably valuable to apply this method to practical use. | Jie Liu Yong Chen Ling Chen Qifu Chen Minfeng Li | 1999 | Chinese Science Bulletin1999，44，3： | 1 |
| 10 | The productivity evaluation model and its application for finite conductivity horizontal wells in fault block reservoirs显示文摘It is very difficult to evaluate the productivity of horizontal wells in fault block reservoirs due to the influence of fault sealing.On the basis of the method of images and source-sink theory,a semianalytical model coupling reservoir and finite conductivity horizontal wellbore flow dynamics was built,in which the influence of fault sealing was taken into account.The distribution of wellbore flow and radial inflow profiles along the horizontal interval were also obtained.The impact of the distance between the horizontal well and the fault on the well productivity was quantitatively analyzed.Based on this analysis,the optimal distance between the horizontal well and the fault in banded fault block reservoirs could be determined.According to the field application,the relative error calculated by the model proposed in this paper is within ±15%.It is an effective evaluation method for the productivity of horizontal wells in fault block reservoirs.The productivity of the horizontal well increases logarithmically as the distance between the horizontal well and the fault increases.The optimal distance between the horizontal well and the fault is 0.25-0.3 times the horizontal well length. | Jiang Hanqiao Ye Shuangjiang Lei Zhanxiang Wang Xing Zhu Guojin Chen Minfeng | 2010 | Petroleum Science2010，7，4： | 1 |
| 11 | The FAPα-activated prodrug Z-GP-DAVLBH inhibits the growth and pulmonary metastasis of osteosarcoma cells by suppressing the AXL pathway显示文摘Osteosarcoma is a kind of bone tumor with highly proliferative and invasive properties,a high incidence of pulmonary metastasis and a poor prognosis.Chemotherapy is the mainstay of treatment for osteosarcoma.Currently,there are no molecular targeted drugs approved for osteosarcoma treatment,particularly effective drugs for osteosarcoma with pulmonary metastases.It has been reported that fibroblast activation protein alpha(FAPa)is upregulated in osteosarcoma and critically associated with osteosarcoma progression and metastasis,demonstrating that FAPa-targeted agents might be a promising therapeutic strategy for osteosarcoma.In the present study,we reported that the FAPa-activated vinblastine prodrug Z-GP-DAVLBH exhibited potent antitumor activities against FAPa-positive osteosarcoma cells in vitro and in vivo.Z-GP-DAVLBH inhibited the growth and induced the apoptosis of osteosarcoma cells.Importantly,it also decreased the migration and invasion capacities and reversed epithelial-mesenchymal transition(EMT)of osteosarcoma cells in vitro and suppressed pulmonary metastasis of osteosarcoma xenografts in vivo.Mechanistically,Z-GP-DAVLBH suppressed the AXL/AKT/GSK-3β/β-catenin pathway,leading to inhibition of the growth and metastatic spread of osteosarcoma cells.These findings demonstrate that Z-GP-DAVLBH is a promising agent for the treatment of FAPa-positive osteosarcoma,particularly osteosarcoma with pulmonary metastases. | Geni Ye Maohua Huang Yong Li Jie Ouyang Minfeng Chen Qing Wen Xiaobo Li Huhu Zeng Pei Long Zepei Fan Junqiang Yin Wencai Ye Dongmei Zhang | 2022 | Acta Pharmaceutica Sinica B2022，12，3： | 1 |
| 12 | Post-traumatic osteoporotic vertebral osteonecrosis treated using balloon kyphoplasty显示文摘 | Genlin Wang Huilin Yang Bin Meng Xuesong Zhu Jun Zou Minfeng Gan Xin Mei Kangwu Chen Tiansi Tang | 2010 | Journal of Clinical Neuroscience2010，，5： | 1 |
| 13 | Kyphoplasty for the Treatment of Painful Osteoporotic Thoracolumbar Burst Fractures显示文摘 | Gan Minfeng Yang Huilin Zhou Feng Zou Jun Wang Genlin Mei Xin Qian Zhonglai Chen Liang | 2010 | Orthopedics (Online)2010，，2： | 1 |
| 14 | A Heat Transfer Numerical Model for Thermoelectric Genera- tor With Cylindrical Shell Sterdy-State Conditions 显示文摘 | Zhou Minfeng HE Yongling CHEN Yanmin | 2014 | ing2014，，68： | 1 |
| 15 | Study and application on the evaluation method of porous formation for long-term waterflooding sand reservoir显示文摘Nine targets which stand both for the static characteristic of produced formations and the dynamic parameter of wells including the average permeability,variation coefficient of permeability,moving capability,remaining recoverable reserves,coefficient of flooding,daily oil production,increasing rate of water cut,cumulative liquid production per unit meter and efficiency index of oil production are selected as the evaluation indexes,a novel model to evaluate the porous formations in long-term waterflooding sand reservoir was established by using the support vector machine and clustering analysis. Data of 57 wells from Shentuo 21 block Shengli oilfield was analyzed by using the model. Four kinds of formation groups were gained. According to the analysis result,different adjustment solutions were put forward to develop the relevant formations. The Monthly oil production increased 7.6 % and the water cut decreased 8.9 % after the adjusted solutions. Good results indicate that the learning from this method gained will be valuable adding to other long-term waterflooding sand reservoirs in Shengli oilfield and other similar reservoirs worldwide. | Wang Changjiang Jiang Hanqiao Chen Minfeng Geng Zhanli Liu Pengfei | 2009 | Engineering Sciences2009，7，3： | 1 |
| 16 | Simulation study on the effect of the microscopic parameters of reservoir pore structure on oil-water relative permeability 显示文摘 | GAO Huimei JIANG Hanqiao CHEN Minfeng | 2007 | Journal of Xi''an Shiyou Uni- versity(Natural Science Edition)2007，22，2： | 1 |
| 17 | Li-MOF-based ions regulator enabling fast-charging and dendrite-free lithium metal anode显示文摘Li metal has been regarded as the holy grail for the next-generation Li-ion battery.Li dendrites issues,however,impede its practical application.In general,prolonging the sand time of Li nucleation and regulating homogeneous Li^(+) flux are effective approaches to suppress the dendrites formation and growth.Regarding this view,a functional polypropylene (PP) separator is developed to regulate ion transportation via a newly designed Li-based metal-organic framework (Li-MOF) coating.The Li-MOF crystallizes in the orthorhombic space group P212121 and features a double-walled three-dimensional (3D) structure with 1D channels.The well-defined intrinsic nanochannels of Li-MOF and the steric-hinerance effect both restrict free migration of anions,contributing to a high Li^(+) transference number of 0.65,which improve the Sand time of Li nucleation.Meanwhile,the Li-MOF coating with uniform porous structure promotes homogeneous Li^(+) flux at the surface of Li metal.Furthermore,the Li-MOF coating layer helps to build solid-electrolyte interphase (SEI) layer that comprises of inorganic Li F and Li_(3)N,which further prohibits the dendrites growth.Consequently,a highly stable Li plating/stripping cycling for over 1000 h is achieved.The functional separator also enables high-performance full lithium metal cells,the high-rate and long-stable cycling performance of Li Ni_(0.8)Mn_(0.1)Co_(0.1)(NMC811)-Li and Li Co O_(2)(LCO)-Li cells further demonstrate the feasibility of this concept. | Xiang Han Tiantian Wu Lanhui Gu Minfeng Chen Jianzhong Song Dan Tian Jizhang Chen | 2023 | Chinese Chemical Letters2023，34，2： | 0 |
| 18 | Liquid-phase sintering enabling mixed ionic-electronic interphases and free-standing composite cathode architecture toward high energy solid-state battery显示文摘Solid-state batteries(SSBs)will potentially offer increased energy density and,more importantly,improved safety for next generation lithium-ion(Li-ion)batteries.One enabling technology is solid-state composite cathodes with high operating voltage and area capacity.Current composite cathode manufacturing technologies,however,suffer from large interfacial resistance and low active mass loading that with excessive amounts of polymer electrolytes and conductive additives.Here,we report a liquidphase sintering technology that offers mixed ionic-electronic interphases and free-standing electrode architecture design,which eventually contribute to high area capacity.A small amount(~4 wt.%)of lithium hydroxide(LiOH)and boric acid(H_(3)BO_(3))with low melting point are utilized as sintering additives that infiltrate into single-crystal Ni-rich LiNi_(0.8)Mn_(0.1)Co_(0.1)(NMC811)particles at a moderately elevated temperature(~350℃)in a liquid state,which not only enable intimate physical contact but also promote the densification process.In addition,the liquid-phase additives react and transform to ionic-conductive lithium boron oxide,together with the indium tin oxide(ITO)nanoparticle coating,mixed ionic-electronic interphases of composite cathode are successfully fabricated.Furthermore,the liquid-phase sintering performed at high-temperature(~800℃)also enables the fabrication of highly dense and thick composite cathodes with a novel free-standing architecture.The promising performance characteristics of such composite cathodes,for example,delivering an area capacity above 8 mAh·cm^(−2) within a wide voltage window up to 4.4 V,open new opportunities for SSBs with a high energy density of 500 Wh·kg^(−1) for safer portable electronic and electrical transport. | Xiang Han Weijun Zhou Minfeng Chen Linshan Luo Lanhui Gu Qiaobao Zhang Jizhang Chen Bo Liu Songyan Chen Wenqing Zhang | 2022 | Nano Research2022，15，7： | 0 |
| 19 | Molten salt synthesis of α-MnO_(2)/Mn_(2)O_(3) nanocomposite as a high-performance cathode material for aqueous zinc-ion batteries显示文摘Thanks to low cost,high safety,and large energy density,aqueous zinc-ion batteries have attracted tremendous interest worldwide.However,it remains a challenge to develop high-performance cathode materials with an appropriate method that is easy to realize massive production.Herein,we use a molten salt method to synthesize nanostructured manganese oxides.The crystalline phases of the manganese oxides can be tuned by changing the amount of reduced graphene oxide added to the reactant mixture.It is found that the α-MnO_(2)/Mn_(2)O_(3) nanocomposite with the largest mass ratio of Mn_(2)O_(3) delivers the best electrochemical performances among all the products.And its rate capability and cyclability can be significantly improved by modifying the Zn anode with carbon black coating and nanocellulose binder.In this situation,the nanocomposite can deliver high discharging capacities of 322.1 and 213.6 mAh g^(-1) at 0.2 and 3 Ag^(-1),respectively.After 1000 cycles,it can retain 86.2% of the capacity at the 2 nd cycle.Thus,this nanocomposite holds great promise for practical applications. | Aixiang Huang Weijun Zhou Anran Wang Minfeng Chen Qinghua Tian Jizhang Chen | 2021 | Journal of Energy Chemistry2021，30，3： | 0 |
| 20 | Pressure Transient Analysis of Arbitrarily Shaped Fractured Reservoirs显示文摘Reservoir boundary shape has a great influence on the transient pressure response of oil wells located in arbitrarily shaped reservoirs. Conventional analytical methods can only be used to calculate transient pressure response in regularly shaped reservoirs. Under the assumption that permeability varies exponentially with pressure drop, a mathematical model for well test interpretation of arbitrarily shaped deformable reservoirs was established. By using the regular perturbation method and the boundary element method, the model could be solved. The pressure behavior of wells with wellbore storage and skin effects was obtained by using the Duhamel principle. The type curves were plotted and analyzed by considering the effects of permeability modulus, arbitrary shape and impermeable region. | Gao Huimei He Yingfu Jiang Hanqia Chen Minfeng | 2007 | Petroleum Science2007，4，2： | 0 |
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