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| 1 | Study on the antiulcer effects of Veronicastrum axillare on gastric ulcer in rats induced by ethanol based on tumor necrosis factor-α(TNF-α)and endothelin-1(ET-1)显示文摘Objective:To assess whether Veronicastrum axillare(V.axillare)can ameliorate ethanol-induced gastric mucosal lesions in rats,reduce the production of pro-inflammatory cytokines,suppress apoptosis and improve local microcirculation disturbances.Methods:Totally 48 male Sprague-Dawley rats were randomly divided into six groups,eight rats in each group.Rats in the normal group and the model group were administered with 0.9%normal saline respectively.Rats in the positive group and ranitidine group were administered with 0.18%ranitidine suspension by intragastric administration respectively.Those in the high dose V.axillare group,the medium dose V.axillare group and the low dose V.axillare group were administrated with V.axillare at the daily dose of 2.8 g/kg,1.4 g/kg and 0.7 g/kg by intragastric administration.Gastric mucosal lesions were produced by intragastric administration of absolute ethanol.Water extract of V.axillare was successively injected for 14 d and last day was injected 1 h before ethanol administration.Gastric mucosal ulcer index and ulcer inhibitory rate were counted by improved Guth methods.The tissue sections were made for pathological histology analysis.Also,we measured the concentrations of tumor necrosis factor-α(TNF-α)and endothelin-1(ET-1)in gastric mucosal,as an index of the pro-inflammatory cytokines,apoptosis and local microcirculation.Besides,the mRNA contents of TNF-αand ET-1 were measured to verify effects on gene expression by real-time fluorescent quantitative PCR.Results:Water extract of V.axillare significantly ameliorated the gastric mucosal lesions induced by ethanol administration(P<0.01).Pro-inflammatory cytokines,TNF-a and ET-1 were increased after ethanol administration and significantly reduced by water extract of V.axillare.The expressions of TNF-αand ET-1 mRNA were also be inhibited by water extract of V.axillare.Conclusion:Current evidences show water extract of V.axillare is effective for defending against ethanol-induced gastric mucosal lesions,significantly inhibiting the production of proinflammatory cytokines and the expressions of TNF-αand ET-1 mRNA,which may be useful for inhibiting apoptosis and improving local microcirculation. | Yong Du Weichun Zhao Leilei Lu Jiayan Zheng Xishi Hu Zhehan Yu Lixin Zhu | 2013 | Asian Pacific Journal of Tropical Biomedicine2013,3,12: | 13 |
| 2 | PtrHB7, a class III HD-Zip Gene, Plays a Critical Role in Regulation of Vascular Cambium Differentiation in Populus显示文摘在树的第二等的生长的一个关键问题是脉管的形成层房间的区别怎么被指导到 concurrentlyform 二不同纸巾:木部或韧皮部。类 III homeodomain 白氨酸拉链(HD 压缩 III ) 基因被知道在主要、第二等的 growth.However 的进程在脉管的系统的开始, patterning,和区别玩 criticalroles,这些基因怎么控制第二等的脉管的区别的机制是未知的。这里,我们显示出那 Populus 类 III HD 压缩基因, PtrHB7,优先地在 cambial 被表示地区。压制 PtrHB7 的植物在木部与减小在脉管的纸巾显示了重要变化但是韧皮部的增加。Transcriptionalanalysis 表明调整木部区别的基因是下面调整的,而基因调整韧皮部 differentiationwere 起来调整。相应地, PtrHB7 overexpression 向木部房间提高了 cambial 房间的区别,但是禁止了韧皮部区别。cambial 房间区别上的 PtrHB7 规定与它的抄本丰富被联系。一起,结果 demonstratedthat PtrHB7 在在剂量依赖者 manner.Key 在 processof Populus 第二等的生长控制在第二等的木部和韧皮部纸巾之间的平衡区别起一个关键作用词: | Yingying Zhu Dongliang Song Jiayan Sun Xingfen Wang Laigeng Li | 2013 | Molecular Plant2013,6,4: | 13 |
| 3 | Selective Synthesis of Mesoporous and Nanorod CeVO4 without Template显示文摘 | Ling Zhu Qin Li Jiayan Li Xiangdong Liu Jian Meng Xueqiang Cao | 2007 | Journal of Nanoparticle Research2007,,2: | 1 |
| 4 | TwoMADS-boxgenes regulate vascularcambium activity and secondary growth by modulating auxin homeostasis in Populus显示文摘In trees,stem secondary growth depends on vascular cambium proliferation activity and subsequent cell differentiation,in which an auxin concentration gradient across the cambium area plays a crucial role in regulating the process.However,the underlying molecular mechanismfor the establishment of auxin concentration is not fully understood.In this study,we identified two function-unknown MADS-box genes,VCM1 and VCM2,which are expressed specifically in the vascular cambium and modulate the subcellular homeostasis of auxin.Simultaneous knockdown of both VCM1 and VCM2 enhanced vascular cambium proliferation activity and subsequent xylem differentiation.Overexpression of VCM1 suppressed vascular cambium activity and wood formation by regulating PIN5 expression,which tuned the soluble auxin concentration in the vascular cambium area.This study reveals the role of VCM1 and VCM2 in regulating the proliferation activity of the vascular cambium and secondary growth by modulating the subcellular auxin homeostasis in Populus. | Shuai Zheng Jiajia He Zengshun Lin Yingying Zhu Jiayan Sun Laigeng Li | 2021 | Plant Communications2021,2,5: | 1 |
| 5 | Preparation and biological activity of quaternized carboxymethylchitosan conjugated with collagen peptide显示文摘 | Xiaoming Zhu Xiaoyu Zhou Jiayan Yi | 2014 | International Journal of Biological Macromolecules2014,70,: | 1 |
| 6 | Selective Synthesis of Mesoporous and Nanorod CeVO4 without Template显示文摘 | Ling Zhu Qin Li Jiayan Li Xiangdong Liu Jian Meng Xueqiang Cao | 2007 | Journal of Nanoparticle Research2007,,2: | 1 |
| 7 | Preparation of CeO 2 –ZrO 2 ceramic fibers by electrospinning显示文摘 | Yanfei Zhang Jiayan Li Qin Li Ling Zhu Xiangdong Liu Xinghua Zhong Jian Meng Xueqiang Cao | 2006 | Journal of Colloid And Interface Science2006,,2: | 1 |
| 8 | Preparation and biological activity of quatemized carboxymethyl chitosan conjugated with collagen peptide显示文摘 | Zhu Xiaoming Zhou Xiaoyu Yi Jiayan | 2014 | Intemational Journal of Biological Macromolecules2014,70,8: | 1 |
| 9 | Influences of Lactiplantibacillus plantarum and Saccharomyces cerevisiae fermentation on the nutritional components,flavor property and lipid-lowering effect of highland barley显示文摘Highland barley is a well-known cereal in Qinghai-Tibet Plateau area with high nutritional value,which has been reported to be a health-promoting grain for the obesity and the diabetes.Fermentation by certain microbiota can improve the flavor property and nutritional characteristics.In the present study,Lactiplantibacillus plantarum and Saccharomyces cerevisiae were singly or jointly applied to ferment highland barley,and the profile of volatile substances and lipid-lowering effects of the respective extracts were analyzed.Results indicated that either L.plantarum or S.cerevisiae or co-fermentation could consume the polysaccharides of highland barley to provide energy,and dramatically increase the contents of total protein and polyphenol.Gas chromatography-mass spectrometry(GC-MS)analysis revealed that the presence of S.cerevisiae was critical for production of the pleasant flavors,especially for the ethyl ester substances including hexadecanoic acid ethyl,hexanoic acid ethyl ester and so on.Meanwhile,we found that fermented highland barley extracts by L.plantarum exhibited stronger lipid-lowering effects in Caenorhabditis elegans than that by S.cerevisiae,while the co-fermentation not only emitted pleasant odors but also exerted high hypolipidemic function.In all,co-fermentation by L.plantarum and S.cerevisiae was proposed to be a promising processing to improve the flavor and functional properties of highland barley. | Juan Bai Linzhao He Jinfu Zhang Xiangyue Gu Beiqi Wu Anlin Wang Ying Zhu Jiayan Zhang Yansheng Zhao Jie Yuan Xiang Xiao | 2024 | Journal of Future Foods2024,4,3: | 0 |
| 10 | Silver-Mediated N-Trifluoromethylation of Amides and Peptides显示文摘Summary of main observation and conclusion We report herein the direct N-trifluoromethylation of N-H amides.Promoted by AgOTf and 2-fluoro-pyridine,the reaction of a variety of amides with Selectfluor,TMSCF3 and CsF proceeds smoothly at room temperature leading to the corresponding N-trifluoromethylated products in satisfactory yields.The protocol is also applicable to amino acid derivatives,resulting in efficient and chemoselective W-trifluoromethylation of di-and tri-peptides with retention of configuration.A mechanism involving reductive elimination of Ag(Ⅲ)intermediates to form N—CF3 bonds is proposed. | Zhenzhen Zhang Jiayan He Lin Zhu Haiwen Xiao Yewen Fang Chaozhong Li | 2020 | Chinese Journal of Chemistry2020,38,9: | 0 |
| 11 | The Impact of Teacher-Student Interaction on Learning Engagement in Blended Learning显示文摘The blended learning environment has the advantages of both traditional teaching and online learning on the Internet,and is highly sought after by educators.As learning engagement is an important guarantee for effective learning outcomes,and teacher-student interaction behaviour is one of the key factors influencing students’learning engagement,it is important to clarify the mechanism between teacher behaviour and learning engagement to optimise teachers’teaching ability,promote students’learning engagement,and enhance their learning outcomes.In this study,a structured questionnaire was used to investigate the online teaching component of blended learning,and the questionnaire was divided into two parts:a survey on student engagement and a survey on student-teacher interaction.Student behavioural input was high but inefficient.Student cognitive input is low.There is a timeliness of student affective engagement. | ZHU Xumei TANG Xiaonan QIAN Jiayan SUN Hong | 2023 | US-China Education Review(A)2023,13,2: | 0 |
| 12 | The Impact of Interaction Methods on Online Learning for English Majors显示文摘Since the outbreak of the epidemic in 2019,online teaching has become one of the most mainstream teaching methods.The huge differences between online and offline teaching have led many teachers and students to try more diverse ways of interacting with each other.Through collecting online teaching and learning data from the online teaching platform(SPOC)of the Contemporary College English course at Xuzhou University of Technology,this project uses the learning analysis method of big data to refine the key factors of interaction models in online and offline hybrid teaching,and to analyse and test the interaction relationships between the factors to explore the types of positive online interaction activities achieved under a hybrid learning environment and the study also explores the types and models of active online interaction activities in a blended learning environment to improve students’learning initiatives and effectiveness. | TANG Xiaonan ZHU Xumei QIAN Jiayan SUN Hong | 2023 | US-China Education Review(B)2023,13,1: | 0 |
| 13 | From lab to market:a review of commercialization and advances for binders in lithium-,zinc-,sodium-ion batteries显示文摘The paper discusses the progress and commercialization of binders for energy storage applications,such as batteries.It explains the role of binders in holding together active materials and current collectors,and highlights the challenges associated with conventional organic solvents in binders.The potential of aqueous binders is introduced as a cost-effective and environmentally friendly alternative.The advantages and limitations of different types of binders are discussed,and the importance of binder selection for optimal battery performance is emphasized.The current state of commercialization of binders is reviewed,and the need for collaboration between researchers,manufacturers,and policymakers to develop and promote environmentally friendly and cost-effective binders is emphasized.The paper concludes by outlining future directions for research and development to further improve the performance and commercialization of binders,while addressing limitations such as lack of standardization,high cost,and long-term stability and reliability. | Chang Su Xuan Gao Kejiang Liu Yuhang Dai Haobo Dong Yiyang Liu Jiayan Zhu Qiuxia Zhang Hongzhen He Guanjie He | 2024 | Nano Research Energy2024,3,1: | 0 |