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| 1 | 42,573 cases of hepatectomy in China: a multicenter retrospective investigation显示文摘Hepatectomy is currently routinely performed in most hospitals in China. China owns the largest population of liver diseases and the biggest number of liver resection cases. A nationwide multicenter retrospective investigation involving 112 hospitals was performed, and focused on liver resection for patients with hepatocellular carcinoma(HCC). 42,573 cases of hepatectomy were enrolled, and 18,275 valid cases of liver resection for HCC patients were selected for statistical analysis. The epidemiology of HCC, distribution of hepatectomy, postoperative complications and prognosis were finally analyzed. In the 18,275 HCC patients,81% had hepatitis B virus infection and 10% had hepatitis C virus infection. 38% of the HCC patients had normal Alphafetoprotein(AFP) level, and other 35% had an AFP level lower than 400 ng mL^(-1). In the study period, 97% of the hepatectomy for HCC were treated with open surgery, and 23.81% had vascular exclusion techniques. The operation time was(191.7±105.6) min,the blood loss was(546.0±562.8) m L, and blood transfusion was(543.0±1,035.2) m L. The median survival for HCC patients was 631 days, with 1-, 3-, and 5-year overall survival of 73.2%, 28.8% and 19.6%, respectively. Liver cirrhosis, multiple nodules,tumor thrombosis and high AFP level were risk factors that affect postoperative survival. | Binhao Zhang Bixiang Zhang Zhiwei Zhang Zhiyong Huang Yifa Chen Minshan Chen Ping Bie Baogang Peng Liqun Wu Zhiming Wang Bo Li Jia Fan Lunxiu Qin Ping Chen Jingfeng Liu Zhe Tang Jun Niu Xinmin Yin Deyu Li Songqing He Bin Jiang Yilei Mao Weiping Zhou Xiaoping Chen | 2018 | Science China(Life Sciences)2018，61，6： | 39 |
| 2 | Estimating biophysical parameters of rice with remote sensing data using support vector machines显示文摘Hyperspectral reflectance (350-2500 nm) measurements were made over two experimental rice fields containing two cultivars treated with three levels of nitrogen application.Four different transformations of the reflectance data were analyzed for their capability to predict rice biophysical parameters,comprising leaf area index (LAI;m-2 green leaf area m-2 soil) and green leaf chlorophyll density (GLCD;mg chlorophyll m 2 soil),using stepwise multiple regression (SMR) models and support vector machines (SVMs).Four transformations of the rice canopy data were made,comprising reflectances (R),first-order derivative reflectances (D1),second-order derivative reflectances (D2),and logarithm transformation of reflectances (LOG).The polynomial kernel (POLY) of the SVM using R was the best model to predict rice LAI,with a root mean square error (RMSE) of 1.0496 LAI units.The analysis of variance kernel of SVM using LOG was the best model to predict rice GLCD,with an RMSE of 523.0741 mg m-2.The SVM approach was not only superior to SMR models for predicting the rice biophysical parameters,but also provided a useful exploratory and predictive tool for analyzing different transformations of reflectance data. | YANG XiaoHua HUANG JingFeng WU YaoPing WANG JianWen WANG Pei WANG XiaoMing Alfredo R. HUETE | 2011 | Science China(Life Sciences)2011，54，3： | 12 |
| 3 | Forms and Balance of Nitrogen and Phosphorus in Cage Culture Waters in Guangdong Province, China显示文摘In order to approach the characteristics of nitrogen and phosphorus pollution caused by cage culture and the balance of nitrogen and phosphorus during the process of cage culture, a monitoring was conducted in Daya Bay of Guangdong Province, China from April 2002 to Jane 2003. The results show that the concentrations of total nitrogen (TN) in the waters at the sites with five and ten years of cage culture history are 1.8 and 2.3 times of that at control site respectively. Ammonium (NH3-N) is the main form of nitrogen in spring while nitrate ( NO3 -) in winter. The concentrations of TN, total dissolved nitrogen (TDN) and dissolved organic nitrogen (DON) are highest in autumn. The concentration of phosphorus increases with the increasing of the culturing time, among which phosphate ( PO 34-) increases most obviously. The concentrations of total phosphorus (TP) and total dissolved phosphorus (TDP) are highest in autumn. The nitrogen and phosphorus are accumulated significantly in the sediment of cage culture area. The model of N balance in the cage culture area: bait (70.62%) + fry (0.28%) + input by tide (14.8%) + release from sediment (14.3%) = harvest of adult fish (12.07%) + deposition into sediment (28.75%) + output by tide (56.18%) + others (3.00%). The model of P balance: bait (83.11%) + fry (0.17%) + input by tide (12.23%) + release from sediment (4.49%) = harvest of adult fish (8.43%) + deposition into sediment (48.59%) + output by tide (41.94%) + others (1.04%). In one fish growth year, the contents of nitrogen and phosphorus in harvest of adult fish are only 17.0% and 10.1% of the contents of nitrogen and phosphorus in fish bait and fry, wherein 83% of nitrogen and more than 89% of phosphorus in fish bait became marine pollutants. | WEN Yanmao WEI Xiange SHU Tingfei ZHOU Jingfeng YU Guanghui LI Feng HUANG Yanyun | 2007 | Chinese Geographical Science2007，17，4： | 9 |
| 4 | Effects of Y on the Microstructure, Mechanical and Bio-corrosion Properties of Mg-Zn-Ca Bulk Metallic Glass显示文摘The micro-alloying effects of Y on the microstructure, mechanical properties, and bio-corrosion behavior of Mg69-xZn27Ca4Yx(x= 0, 1, 2 at.%) alloys were investigated through X-ray diffraction, compressive tests,electrochemical treatments, and immersion tests. The Mg69Zn27Ca4 alloy was found to be absolutely amorphous, and its glass-forming ability decreased with the addition of Y. The Mg68Zn27Ca4Y1 alloy exhibited an ultrahigh compressive strength above 1010 MPa as well as high capacity for plastic strain above 3.1%.Electrochemical and immersion tests revealed that these Y-doped MgeZ neC a alloys had good bio-corrosion resistance in simulated body fluid(SBF) at 37℃. The results of the cytotoxicity test showed high cell viabilities for these alloys, which means good bio-compatibility. | Jingfeng Wang Yang Li Song Huang Yiyun Wei Xingfeng Xi Kaiyong Cai Fusheng Pan | 2014 | Journal of Materials Science & Technology2014，30，12： | 8 |
| 5 | An inertial parameter identification method of eliminating system damping effect for a six-degree-of-freedom parallel manipulator显示文摘A new simple and effective inertial parameter identification method based on sinusoidal vibrations of a six-degree-of-freedom parallel manipulator is proposed. Compared with previously known identification algorithms, the advantages of the new approach are there is no need to design the excitation trajectory to consider the condition number of the observation matrix and the inertial matrix can be accurately defined regardless of the effect of viscous friction. In addition, the use of a sinusoidal exciting trajectory allows calculation of the velocities and accelerations from the measured position response. Simulations show that the new approach has acceptable tolerance of dry friction when using a simple coupling parameter modified formula. The experimental application to the hydraulically driven Stewart platform demonstrates the capability and efficiency of the proposed identification method. | Tian Tixian Jiang Hongzhou Tong Zhizhong He Jingfeng Huang Qitao | 2015 | Chinese Journal of Aeronautics2015，28，2： | 5 |
| 6 | Chinese expert consensus on conversion therapy for hepatocellular carcinoma(2021 edition)显示文摘Recent advances in systemic and locoregional treatments for patients with unresectable or advanced hepatocellular carcinoma(HCC)have resulted in improved response rates.This has provided an opportunity for selected patients with initially unresectable HCC to achieve adequate tumor downstaging to undergo surgical resection,a‘conversion therapy’strategy.However,conversion therapy is a new approach to the treatment of HCC and its practice and treatment protocols are still being developed.Review the evidence for conversion therapy in HCC and develop consensus statements to guide clinical practice.Evidence review:Many research centers in China have accumulated significant experience implementing HCC conversion therapy.Preliminary findings and data have shown that conversion therapy represents an important strategy to maximize the survival of selected patients with intermediate stage to advanced HCC;however,there are still many urgent clinical and scientific challenges for this therapeutic strategy and its related fields.In order to summarize and learn from past experience and review current challenges,the Chinese Expert Consensus on Conversion Therapy for Hepatocellular Carcinoma(2021 Edition)was developed based on a review of preliminary experience and clinical data from Chinese and non-Chinese studies in this field and combined with recommendations for clinical practice.Sixteen consensus statements on the implementation of conversion therapy for HCC were developed.The statements generated in this review are based on a review of clinical evidence and real clinical experience and will help guide future progress in conversion therapy for patients with HCC. | Hui-Chuan Sun Jian Zhou Zheng Wang Xiufeng Liu Qing Xie Weidong Jia Ming Zhao Xinyu Bi Gong Li Xueli Bai Yuan Ji Li Xu Xiao-Dong Zhu Dousheng Bai Yajin Chen Yongjun Chen Chaoliu Dai Rongping Guo Wenzhi Guo Chunyi Hao Tao Huang Zhiyong Huang Deyu Li Gang Li Tao Li Xiangcheng Li Guangming Li Xiao Liang Jingfeng Liu Fubao Liu Shichun Lu Zheng Lu Weifu Lv Yilei Mao Guoliang Shao Yinghong Shi Tianqiang Song Guang Tan Yunqiang Tang Kaishan Tao Chidan Wan Guangyi Wang Lu Wang Shunxiang Wang Tianfu Wen Baocai Xing Bangde Xiang Sheng Yan Dinghua Yang Guowen Yin Tao Yin Zhenyu Yin Zhengping Yu Bixiang Zhang Jialin Zhang Shuijun Zhang Ti Zhang Yamin Zhang Yubao Zhang Aibin Zhang Haitao Zhao Ledu Zhou Wu Zhang Zhenyu Zhu Shukui Qin Feng Shen Xiujun Cai Gaojun Teng Jianqiang Cai Minshan Chen Qiang Li Lianxin Liu Weilin Wang Tingbo Liang Jiahong Dong Xiaoping Chen Xuehao Wang Shusen Zheng Jia Fan 无 | 2022 | Hepatobiliary Surgery and Nutrition2022，11，2： | 4 |
| 7 | Microstructure and mechanical properties of large-scale Mg-Gd-Y-Zn-Mn alloys prepared through semi-continuous casting显示文摘Large-scale Mg-8Gd-4Y-1Zn-Mn(wt.%)alloy ingot with a diameter of 315 mm and a length of 2410 mm was prepared through semi-continuous casting.Chemical composition,microstructure and mechanical properties at different locations of the samples with as-cast,T4 and T6 heat-treated states,respectively,were investigated.No obvious macro segregation has been detected in the high-quality alloy ingot.The main eutectic structures at all different locations are composed ofα-Mg,Mg3RE-type,Mg5RE-type and LPSO phases.At the edge of ingot,the unusual casting twins including 10-12 extension twins and 10-11 compression twins were observed due to the intensive internal stress.In T4 heat-treated alloy,the micro segregation was eliminated.The remained phases wereα-Mg and LPSO phase.Combined with the remarkable age-hardening response,T6 samples exhibits improved mechanical properties at ambient temperature,which derives from the dense prismaticβ'precipitates and profuse basalγ'precipitates. | Kui Wang Jingfeng Wang Xiaoxu Dou Yuanding Huang Norbert Hort Sarkis Gavras Shijie Liu Yanwu Cai Jinxing Wang Fusheng Pan | 2020 | Journal of Materials Science & Technology2020，52，17： | 4 |
| 8 | Development of a novel RNAi therapy:Engineered miR-31 exosomes promoted the healing of diabetic wounds显示文摘Rationale:Chronic wounds associated with diabetes exact a heavy burden on individuals and society and do not have a specific treatment.Exosome therapy is an extension of stem cell therapy,and RNA interference(RNAi)-based therapy is a type of advanced precision therapy.Based on the discovery of chronic wound-related genes in diabetes,we combined exosome therapy and RNAi therapy through an engineering approach for the treatment of diabetic chronic wounds.Methods:We combined exosome therapy and RNAi therapy to establish a precision therapy for diabetes-associated wounds via an engineered exosome approach.Results:First,chronic diabetic wounds express low levels of miR-31-5p compared with nondiabetic wounds,and an miR-31-5p mimic was shown to be effective in promoting the proliferation and migration of three wound-related cell types in vitro.Second,bioinformatics analysis,luciferase reporter assays and western blotting suggested that miR-31-5p promoted angiogenesis,fibrogenesis and reepithelization by inhibiting factor-inhibiting HIF-1(HIF1AN,also named FIH)and epithelial membrane protein-1(EMP-1).Third,engineered miR-31 exosomes were generated as a miR-31-5p RNAi therapeutic agent.In vivo,the engineered miR-31 exosomes promoted diabetic wound healing by enhancing angiogenesis,fibrogenesis and reepithelization.Conclusion:Engineered miR-31 exosomes are an ideal disease pathophysiology-initiated RNAi therapeutic agent for diabetic wounds. | Jinghuan Huang Muyu Yu Wenjing Yin Bo Liang Ang Li Jingfeng Li Xiaolin Li Shichang Zhao Fang Liu | 2021 | Bioactive Materials2021，6，9： | 3 |
| 9 | Evaluating urban expansion and land use change in Shijiazhuang, China, by using GIS and remote sensing显示文摘 | Jieying Xiao Yanjun Shen Jingfeng Ge Ryutaro Tateishi Changyuan Tang Yanqing Liang Zhiying Huang | 2005 | Landscape and Urban Planning2005，，1： | 3 |
| 10 | Enhanced Damping Capacities of Mg–Ce Alloy by the Special Microstructure with Parallel Second Phase显示文摘Microstructure evolution and damping capacities of Mg–Ce binary alloys with three different Ce contents(0.5, 1, or 2 wt%) have been systematically investigated in this work. Numerous fine parallel second phases in Mg–2Ce alloy are obtained, as well as a large number of dislocations around them, but few dislocations appear around the reticular second phase in the Mg–1Ce alloy. Among the three alloys, two internal friction peaks(P_1 and P_2) are detected at about 78 and 167?C in both the Mg–0.5Ce and Mg–1Ce alloys.In addition, the alloy with special parallel second phase structure exhibits excellent damping capacity in both strain amplitude and temperature-dependent regions. These results may be ascribed to the stress concentration and the formation of abundant parallel and uniform dislocation configurations in the ?-Mg matrix without the influence of crystal orientation. The obtained results may provide a novel idea to prepare high-damping magnesium alloys by tailoring their microstructure. | Zhongshan Wu Jingfeng Wang Haibo Wang She Ma Song Huang Shun Li Fusheng Pan | 2017 | Journal of Materials Science & Technology2017，33，9： | 3 |
| 11 | Substitution of Ni for Zn on microstructure and mechanical properties of Mg-Gd-Y-Zn-Mn alloy显示文摘This study analyzes the effect of substitution of Ni for Zn on microstructure and mechanical properties of Mg-Gd-Y-Zn-Mn alloy.Our results show that the volume fraction of Mg5(Gd,Y)and(Mg,Zn)3RE phase decreased and LPSO phase increased with more substitution of Ni.After homogenization,onlyα-Mg and LPSO phase existed.In Mg-Gd-Y-Zn-Mn alloys,the LPSO phases mainly consisted of the 14H type.While in Mg-Gd-Y-Ni-Mn alloy,the LPSO phases consisted of the 18R type.In addition,compared with Mg-Gd-Y-Zn-Mn alloy,the mechanical properties of as-extruded Ni-substitution alloys were improved due to the better refinement of the size of grains and LPSO phases.The tensile strength in as-extruded Mg-Gd-Y-Ni-Mn alloy could reach up to 400 MPa with 18%of the elongation to failure. | Rongqing Zhang Jingfeng Wang Song Huang Shijie Liu Fusheng Pan | 2017 | Journal of Magnesium and Alloys2017，5，3： | 3 |
| 12 | Significance of ST-segment elevation in lead aVR显示文摘To the editor:The aVR lead has been frequently overlooked in the past.Our study indicates that hypertrophic cardiomyopathy needs to be considered in the differential diagnosis of ST-segment elevation in aVR.A 21-year-old woman presented with breathlessness.Over a period of 14 months,she had been unable to play sports owing to dyspnea on exertion.She denied any chest pain,palpitation.She had no prior illness or cardiovascular risk factors.Her physical examination was unremarkable.The electrocardiogram obtained at the time of presentation (Figure 1) showed distinct ST-segment depressions in eight of the 12 electrocardiogram leads.The most striking electrocardiogram abnormality was characterized by a prominent ST-segment elevation of almost 2 mm (0.2 mV) in the aVR lead. | Zhao Yong Wang Jingfeng Huang Guibao Ding Chunhua | 2014 | Chinese Medical Journal2014，，16： | 2 |
| 13 | Detection and estimation of mixed paddy rice cropping patterns with MODIS data显示文摘 | Dailiang Peng Alfredo R. Huete Jingfeng Huang Fuming Wang Huasheng Sun | 2010 | International Journal of Applied Earth Observations and Geoinformation2010，，1： | 2 |
| 14 | Influence of the morphology of long-period stacking ordered phase on the mechanical properties of as-extruded Mg–5Zn–5Y–0.6Zr magnesium alloy显示文摘 | Jingfeng Wang Pengfei Song Xiaoen Zhou Xuefei Huang Fusheng Pan | 2012 | Materials Science & Engineering A2012，，： | 2 |
| 15 | Orthorectification of IKONOS and Impact of Different Resolution DEM显示文摘IKONOS image has been wildly used in city planning, precision agriculture and emergence response. However, the accuracy of IKONOS Geo product is limited due to distortion caused by terrain relief. Orthorectification was performed to remove the distortion and the impact of different DEM on orthorectification were evaluated. 38 ground control points (GCPs) and 25 independent check points (ICPs) were collected. DEMs were generated from 1∶10 000 and 1∶50 000 topographic maps. Results show that RMS error at the check points is 1.554 0 m using DEM generated from 1∶10 000 topographic map, which can meet the accuracy requirement of IKONOS Precision product (1.9 m RMSE). While RMS error is 2.572 4 m using DEM generated from 1∶50 000 topographic map. | XU Junfeng HUANG Jingfeng | 2006 | Geo-Spatial Information Science2006，9，2： | 2 |
| 16 | Improved strength and ductility of AZ31B Mg alloy sheets processed by accumulated extrusion bonding with artificial cooling显示文摘In this study,accumulated extrusion bonding(AEB)process with application of artificial water cooling was successfully performed to fabricate fined-grains AZ31B Mg alloy sheets at 150℃,200℃ and 250℃.The resultant microstructure and mechanical properties are systematically investigated.It reveals that the processing temperature has an important effect on the microstructural evolution during extrusion.During AEB process at 150℃ and 200℃,{10-12}tensile twinning was activated at early stage of extrusion,and subsequently continuous dynamic recrystallization(CDRX)occurred and dominated the further deformation.However,for the sample extruded at 250℃,hardly any twins can be observed,and new fined dynamic recrystallized grains were found along grain boundaries.Artificial cooling was utilized to reduce the rate of grain growth out of the extrusion die,resulting the grains significantly refined from 11μm to 2.5μm.Local high dislocation density region was also observed in the microstructure of sample processed at 150℃ in artificial cooling condition,and the degree decreased with the processing temperature increase.The results summarized from tensile tests indicated that due to the grain refinement the strength and ductility was significantly enhanced(YS of 186 MPa vs.145 MPa,UTS of 391 MPa vs.336 MPa and FE of 31.5%vs.24.5%compared with the as-received sample).Subsequently,annealing treatment at different temperatures was applied to eliminate the high dislocation density.The sample annealed at 200℃ exhibited the best comprehensive mechanical property with YS of 179 MPa,UTS of 390 MPa and FE of 33.0%.As the annealing temperature increasing,the dislocation density was reduced by static recrystallization(SRX)and grain growth,leading to a decreased strength and ductility. | Tingzhuang Han Jingfeng Zou Guangsheng Huang Lifeng Ma Chaojie Che Weitao Jia Lifei Wang Fusheng Pan | 2021 | Journal of Magnesium and Alloys2021，9，5： | 2 |
| 17 | Assessing and characterizing oilseed rape freezing injury based on MODIS and MERIS data显示文摘The oilseed rape growing in the lower reaches of Yangtze River in China belongs to winter varieties and suffers the risk of freezing injury.In this research,a typical freezing injury event occurred in Anhui Province was taken as a case study,the freezing damage degree of oilseed rape was assessed,and its development characteristics based on the vegetation metrics derived from MODIS and MERIS data were investigated.The oilseed rape was mapped according to the decline of greenness from bud stage to full-bloom period,with the phenological phases identified adopting time-series analyses.NDVI was more sensitive to freezing injury compared with other commonly used vegetation indices(VIs)calculated using MODIS bands,e.g.,EVI,GNDVI and SAVI.The freezing damage degree employing the difference between post-freeze growth and the baseline level in adjacent damage-free growing seasons was determined.The remote sensing-derived damage levels were supported by their correlation with the cold accumulated temperatures at the county level.The performance of several remote sensing indicators of plant biophysical and biochemical parameters was also investigated,i.e.,the photosynthetic rate,canopy water status,canopy chlorophyll content,leaf area index(LAI)and the red edge position(REP),in response to the advance of the freezing damage.It was found that the photosynthetic rate indicator—Photochemical Reflectance Index(PRI)responded strongly to freezing stress.Freezing injury caused canopy water loss,which could be detected though the magnitude was not very large.MERIS-LAI showed a slow and lagging response to low temperature and restored rapidly in the recovery phase;additionally,REP and the indicator of canopy chlorophyll content—MERIS Terrestrial Chlorophyll Index(MTCI),did not appear to be influenced by freezing injury.It was concluded that the physiological functions,canopy structure,and organic content metrics showed a descending order of vulnerabilities to freezing injury. | She Bao Huang Jingfeng Zhang Dongyan Huang Linsheng | 2017 | International Journal of Agricultural and Biological Engineering2017，10，3： | 2 |
| 18 | Vegetation water content estimation for corn and soybeans using spectral indices derived from MODIS near- and short-wave infrared bands显示文摘 | Daoyi Chen Jingfeng Huang Thomas J. Jackson | 2005 | Remote Sensing of Environment2005，，2： | 1 |
| 19 | Transpacific transport and evolution of the optical properties of Asian dust显示文摘 | Zhaoyan Liu T. Duncan Fairlie Itsushi Uno Jingfeng Huang Dong Wu Ali Omar Jayanta Kar Mark Vaughan Raymond Rogers David Winker Charles Trepte Yongxiang Hu Wenbo Sun Bing Lin Anning Cheng | 2013 | Journal of Quantitative Spectroscopy and Radiative Transfer2013，，： | 1 |
| 20 | Effect of Gd and Y contents on the microstructural evolution of long period stacking ordered phase and the corresponding mechanical properties in Mg–Gd–Y–Zn–Mn alloys显示文摘 | Song Huang Jingfeng Wang Fan Hou Xiuhong Huang Fusheng Pan | 2014 | Materials Science & Engineering A2014，，： | 1 |
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