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| 1 | Lignin biosynthesis by suppression of two O-methyl-transferases显示文摘Caffeic acid O-methyltransferase (COMT) and caffeoyl-CoA-3-O-methyltransferase (CCoAOMT) genes encode two methyltransferases at different substrate levels in lignin biosynthesis. We constructed two single antisense expression vectors containing the cDNA of COMT or CCoAOMT genes and one dual antisense expression vector containing cDNAs of both OMTs genes. The antisense constructs were transferred into tobacco mediated by Agrobac-terium tumefacience. PCR-Southern analysis indicated that antisense cDNAs had been integrated into the genome of the transgenic tobacco. The antisense genes were also expressed at transcriptional level displayed by Northern dot analysis. Klason lignin assay of 3-month-old transgenic tobaccos showed that repression in COMT or CCoAOMT alone could result in reduction of lignin content, more reduction was caused by suppression in CCoAOMT than in COMT. Furthermore, simultaneous suppression of both COMT and CCoAOMT resulted in more reduction than that of single gene, which indicated | ZHAO Huayan WEI Jianhua ZHANG Jinyu LIU Huirong WANG Tai SONG Yanru | 2002 | Chinese Science Bulletin2002，47，13： | 7 |
| 2 | Glucose-regulated protein 75 suppresses apoptosis induced by glucose deprivation in PC12 cells through inhibition of Bax conformational change显示文摘调整葡萄糖的蛋白质(Grp75 ) 75 是属于热吃惊蛋白质的重要分子的女伴 70 家庭并且在线粒体主要住。Grp75 能保护房间免受葡萄糖剥夺(GD ) 的伤害损害。然而,它由执行这功能的分子的机制是未知的。这里,我们报导 Grp75 能推迟细胞色素 c 的版本,还原剂 apoptosis 由 GD 导致,并且我们也发现 Grp75 能减少 Bax/Bcl-2 基因表示比率并且在这个过程期间禁止 Bax 的 conformational 变化。在结论,这些调查结果建议 Grp75 overexpression 能禁止 GD 导致的 apoptosis。Grp75 禁止了 Bax conformational 变化推迟细胞色素 c 的版本,因此提供保护给对 GD 毒性首先被用作一个神经原模型的 PC12 房间。 | Ling Yang Xiaoyu Liu Jinyu Hao Yunlong Yang Mingxia Zhao Ji Zuo Wen Liu | 2008 | Acta Biochimica et Biophysica Sinica2008，40，4： | 6 |
| 3 | Experimental and measured research on three-dimensional deformation law of gas drainage borehole in coal seam显示文摘Using self-researched gas drainage borehole stability dynamic monitoring device, three-dimensional deformation characteristics of borehole under steady vertical load were researched experimentally and systematically. This research indicated that under the action of steady loading, the mechanical deformation path of the simulated gas drainage borehole is gradually complicated, and the decay of the borehole circumferential strain is an important characterization of the prediction and early warning of borehole instability and collapse. The horizontal position of borehole occurs compressive strain, and the vertical of which occurs tensile strain under the action of vertical stress. At the initial stage of loading, the vertical strain is more sensitive than that in the horizontal direction. After a certain period of time, the horizontal strain is gradually higher than the vertical one, and the intersection of the borehole horizontal diameter and the hole wall is the stress concentration point. With the increase of the depth of hole, the strain shows a gradual decay trend as a whole, and the vertical strain decays more observably, but there is no absolute position correlation between the amount of strain decay and the increase in borehole depth,and the area within 1.5 times the orifice size is the borehole stress concentration zone. | Hongbao Zhao Jinyu Li Yihong Liu Yikuo Wang Tao Wang Hui Cheng | 2020 | International Journal of Mining Science and Technology2020，30，3： | 5 |
| 4 | Small RNA transcriptome investigation based on next-generation sequencing technology显示文摘在过去的十年,有学习小 RNA transcriptome 为理解 transcriptional 规定的复杂性是必要的一条成长认识。与增加的产量和减少的费用,下一代的定序技术提供了一个崭新的机会测量小 RNA transcriptome 的程度和复杂性。同时,大量获得的数据和改变的技术平台也为有效数据分析和采矿提出了多重挑战。提供某卓见进小 RNA transcriptome 调查,这评论描述主要小 RNA 班,识别小 RNA 的试验性的方法,和可得到的生物信息学工具和数据库。 | Linglin Zhou Xueying Li Qi Liu Fangqing Zhao Jinyu Wu | 2011 | Journal of Genetics and Genomics2011，38，11： | 5 |
| 5 | Effect of addition of Al-Si eutectic alloy on microstructure and mechanical properties of Mg-12wt%Li alloy显示文摘Mg-12 Li, Mg-12 Li-3(Al-Si), Mg-12 Li-7(Al-Si) and Mg-12 Li-9(Al-Si) alloys(all in wt%) were fabricated by high frequency vacuum induction melting in a water cooled copper crucible. After subsequently hotrolling and annealing, their microstructure and mechanical properties were investigated. Experimental results show that mechanical properties of Mg-12 Li alloy were significantly improved by the addition of Al-Si eutectic alloy. Mg-12 Li-7(Al-Si) alloy shows the highest strength of 196 MPa of the investigated alloys, which is about 1.8 times of the strength of Mg-12 Li alloy, and maintains high elongation of 27%.The improved mechanical property with addition of Al and Si in the eutectic proportion into Mg-12 Li alloy was attributed to the solution strengthening effect of A1 and precipitation hardening effect from AlLi and Mg_2 Si precipitates. | Zilong Zhao Xuegang Xing Jinyu Ma Liping Bian Wei Liang Yide Wang | 2018 | Journal of Materials Science & Technology2018，34，9： | 5 |
| 6 | Recovery of rare earths and aluminum from FCC waste slag by acid leaching and selective precipitation显示文摘This paper investigated the recovery of rare earth elements(REEs) and aluminum(AI) from the waste slag discharged by FCC catalyst factory(FCC waste slag) via acid leaching and selective precipitation.Analysis methods such as ICP-AES, XRF and XRD were applied to obtain experiment data. The maximum leaching efficiency of REEs and Al was achieved at pH value of 1 and with liquid to solid ratio of 4:1,Under such conditions, 91.01%, 92.24% and 94.77% of La, Ce and Al were extracted at 20 ℃ for 2 h from the FCC waste slag, respectively. The SiO_2 content in the leaching residue was 88.3%, which can be used as an available silicon resource. The REEs can be precipitated in the form of REEs and sodium double sulfate(NaRE(SO_4)_2·xH_2 O) by adding Na_2 SO_4 to the leaching solution, while Al remained in the solution. Afterwards, the pH value of the filtrate was adjusted to 4.5, and Al was precipitated as AI(OH)_3. Finally,NaRE(SO_4)_2·xH_2 O and Al(OH)_3 were converted into RECl_3 and Al_2(SO4)_3 solution,respectively, which were recycled to manufacture zeolite. This process recovered REEs and Al from the FCC waste slag and reduced the emissions of waste slag simultaneously, which has an important economic and environment significance. | Jinyu wang Xiaowei Huang Dali Cui Liangshi Wang Zongyu Feng Bin Hu Zhiqi Long Na Zhao | 2017 | Journal of Rare Earths2017，35，11： | 4 |
| 7 | The normal cell proliferation and wound healing effect of polysaccharides from Ganoderma amboinense显示文摘To study the cell proliferation and wound healing activity of polysaccharides from Ganoderma amboinense(GAMPS),the polysaccharide was extracted by water extraction and alcohol precipitation method,and its monosaccharide composition and molecular weight were analyzed.The effects of different concentrations of GAMPS on the cell proliferation were determined by cell survival rate test,and the wound healing ability of GAMPS to NIH/3T3 cells was detected.The preliminary evaluation of the antioxidant ability of GAMPS was conducted by the oxygen radical absorbance capacity(ORAC).The results showed that the GAMPS was composed of glucose,mannose,and galactose at a molar ratio of 67.62:14.07:7.50,and the weightaverage molecular weights were 5.439×10^(6) and 1.704×10^(5) g/mol by using high-performance gel-permeation chromatography-multiple angle laser scatter(HPGPC-MALS)analysis.GAMPS(0.2μg/μL)showed the strongest proliferation ability to THP-1 cells,with cell survival rate of 178.7%.The wound healing effect of GAMPS(0.1μg/μL)was obvious on NIH/3T3 and 3.75μg/μL of GAMPS showed the strongest total antioxidant ability.All the results indicate that GAMPS promotes cell proliferation,and has cell wound healing effect and strong antioxidant activity.The results provide theoretical foundation for the development and utilization of GAMPS. | Shuangzhi Zhao Ming Lei Hui Xu Hailun He Alexander Suvorov Junhua Wang Jiying Qiu Qingxin Zhou Jinyu Yang Leilei Chen | 2021 | Food Science and Human Wellness2021，10，4： | 4 |
| 8 | The metastable constituent effects on size-dependent deformation behavior of nanolaminated micropillars: Cu/FeCoCrNi vs Cu/CuZr显示文摘Metastable high entropy alloys(HEAs) and amorphous metallic glasses(MGs), with the chemical disordered character, are intensively studied due to their excellent performance. Here, we introduce Cu to separately constrain these two metastable materials and comparatively investigate their deformation behaviors and mechanical properties of Cu/HEA Fe Co Cr Ni and Cu/MG Cu Zr nanolaminated micropillars in terms of intrinsic layer thickness h and extrinsic pillar diameter D. The metastable HEA layers, as the hard phase in Cu/HEA micropillars, are stable and dominate the deformation, while transformation(crystallization) occurs in MG which plays a minor role in deformation of Cu/MG micropillars. The h-controlled deformation mode transits from the D-independent homogenous-like deformation at large h to the Ddependent shear banding at small h in both Cu/HEA and Cu/MG micropillars. Although both Cu/HEA and Cu/MG micropillars exhibit a maximum strain hardening capability controlled by h, the former manifests much lower hardening capability compared with the latter. The intrinsic size h and extrinsic size D have a strong coupling effect on the strength of Cu/HEA and Cu/MG micropillars. The strength of strength of Cu/HEA micropillars exhibits the D-dependent transition from 'smaller is stronger' to 'smaller is weaker'with increasing h. By contrast, the strength of Cu/MG micropillars exhibits the transition from bulk-like D-independent behavior at large h to small volume D-dependent behavior(smaller is stronger) at small h. | Yufang Zhao Jinyu Zhang YaQiang Wang Shenghua Wu Xiaoqing Liang Kai Wu Gang Liu Jun Sun | 2021 | Journal of Materials Science & Technology2021，，9： | 3 |
| 9 | Low intensity near-infrared light promotes bone regeneration via circadian clock protein cryptochrome 1显示文摘Bone regeneration remains a great clinical challenge. Low intensity near-infrared(NIR) light showed strong potential to promote tissue regeneration, offering a promising strategy for bone defect regeneration. However, the effect and underlying mechanism of NIR on bone regeneration remain unclear. We demonstrated that bone regeneration in the rat skull defect model was significantly accelerated with low-intensity NIR stimulation. In vitro studies showed that NIR stimulation could promote the osteoblast differentiation in bone mesenchymal stem cells(BMSCs) and MC3T3-E1 cells, which was associated with increased ubiquitination of the core circadian clock protein Cryptochrome 1(CRY1) in the nucleus. We found that the reduction of CRY1 induced by NIR light activated the bone morphogenetic protein(BMP) signaling pathways, promoting SMAD1/5/9 phosphorylation and increasing the expression levels of Runx2 and Osterix. NIR light treatment may act through sodium voltage-gated channel Scn4a, which may be a potential responder of NIR light to accelerate bone regeneration. Together, these findings suggest that low-intensity NIR light may promote in situ bone regeneration in a CRY1-dependent manner, providing a novel, efficient and non-invasive strategy to promote bone regeneration for clinical bone defects. | Jinfeng Peng Jiajia Zhao Qingming Tang Jinyu Wang Wencheng Song Xiaofeng Lu Xiaofei Huang Guangjin Chen Wenhao Zheng Luoying Zhang Yunyun Han Chunze Yan Qian Wan Lili Chen | 2022 | International Journal of Oral Science2022，14，4： | 2 |
| 10 | Hepatitis C and Alcohol Exacerbate Liver Injury by Suppression of FOXO3显示文摘 | Batbayar Tumurbaatar Irina Tikhanovich Zhuan Li Jinyu Ren Robert Ralston Sudhakiranmayi Kuravi Roosevelt Campbell Gaurav Chaturvedi Ting-Ting Huang Jie Zhao Junfang Hao Maura O’Neil Steven A. Weinman | 2013 | The American Journal of Pathology2013，，6： | 2 |
| 11 | Petrogenesis of Jurassic Granitoids on Liaodong Peninsula,Northeast China:Constraints on the Evolution of the Mongol-Okhotsk and Pacific Tectonic Regimes显示文摘The tectonic setting of Jurassic magmatism in the Northeast China(NE China)is unclear.Here,we present new petrological,whole-rock geochemical,zircon U-Pb geochronological,and zircon Lu-Hf isotope data for Jurassic granitoids of the Wulong region,Liaodong Peninsula,NE China.Laser ablation-inductively coupled plasma-mass spectrometry(LA-ICP-MS)zircon U-Pb data indicate that these granitoids were emplaced at 165-156 Ma.The biotite monzogranite,two-mica monzogranite,monzogranite,granodiorite,biotite granodiorite,and syenogranite are strongly peraluminous(A/CNK=1.09-1.29),contain peraluminous minerals such as muscovite,have high normative corundum abundances(1.26 wt.%-3.28 wt.%),and have high K2_(O)/Na2O ratios(0.76-1.48),all of which indicate an S-type granite affinity.However,the biotite granodiorite and syenogranite have high Sr(391 ppm-570 ppm)and low Y(3.06 ppm-5.94 ppm)contents,with high Sr/Y(65.8-185.9)ratios,and the two-mica monzogranite,monzogranite,and granodiorite have relatively high Sr(138 ppm-379 ppm)and low Y(3.38 ppm-8.71 ppm)contents,with high Sr/Y ratios(19.1-77.9).All of the analyzed samples have negative zircon eHf(t)values(-41.4 to-20.6)with old two-stage Hf model ages(TDM2(Hf)=2.50-3.76 Ga).Therefore,we infer that the biotite monzogranite is the typical feature of S-type granite that was derived by partial melting of metagraywacke.The monzogranite,two-mica monzogranite,granodiorite,biotite granodiorite,and syenogranite exhibit geochemical characteristics of S-type granite with K-rich adakitic features,and were possibly derived by mixing of melts from clastic crustal materials and ada-kitic magmas.There are voluminous Jurassic igneous rocks in the NE China.By combining our study with the previous researches,this paper infers that the Jurassic magmatism within the Erguna-Xing'an Massif was related to the southward subduction and closure of the Mongol-Okhotsk Ocean;the Early Jurassic magmatism to the east of the Songliao Basin and in the northern North China Cra-ton(NCC)was related to the subduction of the Pacific Plate;however,the Middle-Late Jurassic igne-ous rocks to the west of the Songliao Basin were related to the closure of the Mongol-Okhotsk Ocean and,in the northern NCC,were related to closure of the Mongol-Okhotsk Ocean with an influence from flat-slab subduction of the Pacific Plate. | Jinyu Li Ye Qian Leontine Tekoumc Changji Zhao Jinlei Sun Tao Zheng Fengyue Sun Yanjie Shen | 2021 | Journal of Earth Science2021，32，1： | 2 |
| 12 | A Review of In‑Situ Techniques for Probing Active Sites and Mechanisms of Electrocatalytic Oxygen Reduction Reactions显示文摘Electrocatalytic oxygen reduction reaction(ORR)is one of the most important reactions in electrochemical energy technologies such as fuel cells and metal–O2/air batteries,etc.However,the essential catalysts to overcome its slow reaction kinetic always undergo a complex dynamic evolution in the actual catalytic process,and the concomitant intermediates and catalytic products also occur continuous conversion and reconstruction.This makes them difficult to be accurately captured,making the identification of ORR active sites and the elucidation of ORR mechanisms difficult.Thus,it is necessary to use extensive in-situ characterization techniques to proceed the real-time monitoring of the catalyst structure and the evolution state of intermediates and products during ORR.This work reviews the major advances in the use of various in-situ techniques to characterize the catalytic processes of various catalysts.Specifically,the catalyst structure evolutions revealed directly by in-situ techniques are systematically summarized,such as phase,valence,electronic transfer,coordination,and spin states varies.In-situ revelation of intermediate adsorption/desorption behavior,and the real-time monitoring of the product nucleation,growth,and reconstruction evolution are equally emphasized in the discussion.Other interference factors,as well as in-situ signal assignment with the aid of theoretical calculations,are also covered.Finally,some major challenges and prospects of in-situ techniques for future catalysts research in the ORR process are proposed. | Jinyu Zhao Jie Lian Zhenxin Zhao Xiaomin Wang Jiujun Zhang | 2023 | Nano-Micro Letters2023，15，2： | 2 |
| 13 | Genomic Variations in the Tea Leafhopper Reveal the Basis of Its Adaptive Evolution显示文摘Tea green leafhopper(TGL),Empoasca onukii,is of biological and economic interest.Despite numerous studies,the mechanisms underlying its adaptation and evolution remain enigmatic.Here,we use previously untapped genome and population genetics approaches to examine how the pest adapted to different environmental variables and thus has expanded geographically.We complete a chromosome-level assembly and annotation of the E.onukii genome,showing notable expansions of gene families associated with adaptation to chemoreception and detoxification.Genomic signals indicating balancing selection highlight metabolic pathways involved in adaptation to a wide range of tea varieties grown across ecologically diverse regions.Patterns of genetic variations among 54 E.onukii samples unveil the population structure and evolutionary history across different tea-growing regions in China.Our results demonstrate that the genomic changes in key pathways,including those linked to metabolism,circadian rhythms,and immune system functions,may underlie the successful spread and adaptation of E.onukii.This work highlights the genetic and molecular basis underlying the evolutionary success of a species with broad economic impacts,and provides insights into insect adaptation to host plants,which will ultimately facilitate more sustainable pest management. | Qian Zhao Longqing Shi Weiyi He Jinyu Li Shijun You Shuai Chen Jing Lin Yibin Wang Liwen Zhang Guang Yang Liette Vasseur Minsheng You | 2022 | Genomics, Proteomics & Bioinformatics2022，20，6： | 1 |
| 14 | QNE1 is a key flowering regulator determining the length of the vegetative period in soybean cultivars显示文摘The soybean E1 gene is a major regulator that plays an important role in flowering time and maturity.However,it remains unclear how cultivars carrying the dominant E1 allele adapt to the higher latitudinal areas of northern China.We mapped the novel quantitative trait locus QNE1(QTL near E1) for flowering time to the region proximal to E1 on chromosome 6 in two mapping populations.Positional cloning revealed Glyma.06G204300,encoding a TCP-type transcription factor,as a strong candidate gene for QNE1.Association analysis further confirmed that functional single nucleotide polymorphisms(SNPs) at nucleotides 686 and 1,063 in the coding region of Glyma.06G204300 were significantly associated with flowering time.The protein encoded by the candidate gene is localized primarily to the nucleus.Furthermore,soybean and Brassica napus plants overexpressing Glyma.06G204300 exhibited early flowering.We conclude that despite their similar effects on flowering time,QNE1 and E4 may control flowering time through different regulatory mechanisms,based on expression studies and weighted gene co-expression network analysis of flowering time-related genes.Deciphering the molecular basis of QNE1 control of flowering time enriches our knowledge of flowering gene networks in soybean and will facilitate breeding soybean cultivars with broader latitudinal adaptation. | Zhengjun Xia Hong Zhai Yanfeng Zhang Yaying Wang Lu Wang Kun Xu Hongyan Wu Jinglong Zhu Shuang Jiao Zhao Wan Xiaobin Zhu Yi Gao Yingxiang Liu Rong Fan Shihao Wu Xin Chen Jinyu Liu Jiayin Yang Qijian Song Zhixi Tian | 2022 | Science China(Life Sciences)2022，65，12： | 1 |
| 15 | Morphological control of highly ordered mesoporous silica SBA-15显示文摘 | Zhao Dongyuan Sun Jinyu Li Quanzhi | 2000 | Chem Mater2000，12，： | 1 |
| 16 | Synthesis, morphology control, and properties of porous metal–organic coordination polymers显示文摘 | Limin Huang Huanting Wang Jinxi Chen Zhengbao Wang Jinyu Sun Dongyuan Zhao Yushan Yan | 2002 | Microporous and Mesoporous Materials2002，，2： | 1 |
| 17 | Operation of LECR3显示文摘 | Feng Yueheng Ma Baohua Wang Hui Li Jinyu Cao Yun Shang Yong Lu Wang Sha Shan Ma Hongyi Zhang Wenhui Lin Shuhao Li Xixia Zhao Huanyu Miao Tingting Guo Xiaohong Zhang Xuezhen Sun Liangting | 2009 | 近代物理研究所和兰州重离子加速器实验室年报:英文版2009，，1： | 1 |
| 18 | Fast valve power loss evaluation method for modular multi-level converter operating at high-frequency显示文摘There is no common accepted way for calculating the valve power loss of modular multilevel converter(MMC).Valve power loss estimation based on analytical calculation is inaccurate to address the switching power loss and valve power loss estimation based on detailed electro-magnetic simulation is of low speed.To solve this problem,a method of valve power loss estimation based on the detailed equivalent simulation model of MMC is proposed.Results of valve power loss analysis of 201-level 500MW MMC operating at 50Hz~1000Hz are presented.It is seen that the valve power loss of a MMC increased by 12,40 and 93%under 200Hz,500Hz and 1000Hz operating frequency.The article concludes that in a device with isolated inner AC system,MMC operating at higher frequency will be more competitive than typical 50Hz/60Hz MMC with moderate increase of operating power loss and significant reduction of the size of the AC components. | Fen Tao Zhujun Xie Jie Cheng Chenghao Li Lu Zhao Jinyu Wen | 2016 | Protection and Control of Modern Power Systems2016，1，1： | 1 |
| 19 | Morphological control of highly ordered large pore mesoporous silica SBA-15显示文摘 | ZHAO Dongyuan SUN Jinyu LI Quanzhi | 2000 | Chem Mater2000，12，： | 1 |
| 20 | Synthe- sis of isoamyl salicylate using a novel mesoporous ti-tania superacid as a catalyst显示文摘 | Qian Zhao Jinyu Chu Tingshun Jiang | 2008 | Korean J Chem Eng2008，25，5： | 1 |
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