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| 1 | Floor heave in the west wing track haulage roadway of the Tingnan Coal Mine: Mechanism and control显示文摘Floor heave of a roadway is a dynamic phenomenon that often happens in the roadways of coal mines. It seriously affects safe production in the coal mine. Floor heave has long been one of the most difficult problems to be resolved during coal mining. An analysis of floor heave in the soft rock surrounding the roadway, and the factors influencing it, allowed the deformation mechanism in the west wing double track haulage roadway of the Tingnan Coal Mine to be deduced. Three types of floor heave are observed there: intumescent floor heave, extrusion and mobility floor heave, and compound floor heave. Control measures are proposed that have been adopted during a recent repair engineering project. Control of the floor heave in the west wing track haulage roadway was demonstrated. The reliability and rationality of a combined support technology including floor anchors, an inverted arch, and anchoring of both sides was verified by mine pressure data and the field observations. Waterproofing measures were also under-taken to assist in the control of floor heave. | Wang Jiong | 2012 | International Journal of Mining Science and Technology2012，22，3： | 18 |
| 2 | Prenatal diagnosis of methylmalonic aciduria by analysis of organic acids and total homocysteine in amniotic fluid显示文摘背景:Methylmalonic 酸尿(MMA ) 是在中国的器官的酸尿的最经常的疾病。各种各样的生物化学的策略为 MMA 的出生前的诊断被跟随。然而,后来, MMA 影响的胎儿减少了 methylmalonic 酸的排泄,出生前的生物化学的诊断的困难是明显的。煤气的层析团分光术(GC/MS ) 和双人脚踏车团分光术(ESI/MS/MS ) 允许我们在影响胎儿识别疾病。这研究的目的是在 MMA 的出生前的诊断在羊膜的液体决定有机酸和全部的人半胱氨酸的分析的价值。方法:临床诊断并且有 MMA 的九个职业人员乐队的结果并且出生前在风险基于九个胎儿的生物化学的分析诊断因为 MMA 被调查。从在为 MMA 的风险的怀孕和新陈代谢的联盟者正常怀孕的羊膜的液体样品在 16 点被获得 - 24 星期怀孕期。Methylmalonic 酸和甲基枸橼酸被 GC/MS 测量, propionylcarnitine 被 ESI/MS/MS 分析,并且全部的人半胱氨酸由荧光极化免疫分析是坚定的。结果:在二怀孕, methylmalonic 酸的高水平,甲基枸橼酸, propionylcarnitine,和总数,人半胱氨酸在胎儿显示了联合 MMA 和 homocysteinemia。继续的怀孕和收到的维生素 B12 作为出生前的处理,和其它补充的母亲之一终止了她的怀孕。在一个,怀孕, methylmalonic 酸的显著地提高的层次,甲基枸橼酸,和 propionylcarnitine,和正常全部的人半胱氨酸铺平被发现在胎儿显示孤立的 MMA;流产在这个案例上被执行。在另外的六怀孕,上述提及的代谢物的所有层次是正常的建议胎儿没被 MMA 影响。diagnoses 被严峻的尿有机酸和血浆总数人半胱氨酸在交货以后证实。结论:MMA 的新陈代谢的畸形在怀孕期早发生。在羊膜的液体的全部的人半胱氨酸的水平可以是胎儿的联合 MMA 和 homocysteinemia 的另外的指示物。在羊膜的液体的全部的人半胱氨酸水平的决心可以为疾病的出生前的诊断成为一个方便、可靠的方法。 | ZHANG Yao YANG Yan-ling HASEGAWA Yuki YAMAGUCHI Seiji SHI Chun-yan SONG Jin-qing SAYAMI Sujan LIU Ping YAN Rong DONG Jin-hua QIN Jiong | 2008 | Chinese Medical Journal2008，，3： | 18 |
| 3 | An Integrated Analysis of Risk Factors of Cognitive Impairment in Patients with Severe Carotid Artery Stenosis显示文摘Objective To investigate cognitive dysfunction in patients with carotid artery stenosis(CAS) and potential risk factors related to cognitive-especially memory-dysfunction. Methods Forty-seven patients with carotid artery stenosis were recruited into our study cohort. The Mini-Mental State Examination(MMSE) and the Montreal Cognitive Assessment(MoCA) were adopted to assess cognitive function, the Wechsler Memory Scale(WMS) to assess memory function, high-resolution MRI and enhanced ultrasound to evaluate carotid plaques, and computed tomography perfusion(CTP) imaging to evaluate intracranial blood perfusion. Single-factor analysis and multiple-factor regression analysis were used to analyze potential risk factors of cognitive impairment. Results Mini-Mental State Examination test results showed that 22 patients had cognitive impairment, and MoCA test results showed that 10 patients had cognitive impairment. Analysis of various risk factors indicated that the average memory quotient of female patients was higher than that of males(P = 0.024). The cognitive and memory performance of those with an educational background above high school were significantly better than those of participants with high school or lower(P = 0.045). Patients with abnormal intracranial perfusion performed worse on the MMSE test(P = 0.024), and their WMS scores were significantly lower(P = 0.007). The MMSE scores and the memory quotients were significantly lower in patients with a history of cerebral infarction(MMSE, P = 0.047, memory quotient score, P = 0.018). Conclusion A history of cerebral infarction and abnormal cerebral perfusion are associated with decline in overall cognitive function and memory in patients with carotid stenosis. Being female and having an educational background above high school may be protective factors in the development of cognitive dysfunction. | LUO Ru Tao WANG Pei Jiong DENG Xiao Feng ZHOU Shu Jie ZHAO Meng QIAN Jing ZHANG Dong WANG Rong ZHANG Yan | 2018 | Biomedical and Environmental Sciences2018，31，11： | 17 |
| 4 | Sequential invasive-noninvasive mechanical ventilation weaning strategy for patients after tracheostomy显示文摘BACKGROUND: Because the continuity and integrity of the trachea are likely damaged to some extent after tracheostomy, the implementation of sequential ventilation has certain difficulties, and sequential invasive-noninvasive ventilation on patients after tracheostomy is less common in practice. The present study aimed to investigate the feasibility of invasive-noninvasive sequential weaning strategy in patients after tracheostomy.METHODS: Fifty patients including 24 patients with withdrawal of mechanical ventilation(conventional group) and 26 patients with sequential invasive-noninvasive weaning by directly plugging of tracheostomy(sequential group) were analyzed retrospectively after appearance of pulmonary infection control(PIC) window. The analysis of arterial blood gases, ventilator-associated pneumonia(VAP) incidence, the total duration of mechanical ventilation, the success rate of weaning and total cost of hospitalization were compared between the two groups.RESULTS: Arterial blood gas analysis showed that the sequential weaning group was better than the conventional weaning group 1 and 24 hours after invasive ventilation. The VAP incidence was lowered, the duration of mechanical ventilation shortened, the success rate of weaning increased, and the total cost of hospitalization decreased.CONCLUSION: Sequential invasive-noninvasive ventilator weaning is feasible in patients after tracheostomy. | Xue-xue Pu Jiong Wang Xue-bo Yan Xue-qin Jiang | 2015 | World Journal of Emergency Medicine2015，6，3： | 17 |
| 5 | School and community physical activity characteristics and moderate-to-vigorous physical activity among Chinese school-aged children: A multilevel path model analysis显示文摘Purpose: The purpose of this study was to examine the association between school and community physical activity(PA) characteristics and levels of moderate-to-vigorous physical activity(MVPA) among Chinese school children.Methods: Data were obtained from the 2016 Physical Activity and Fitness in China—The Youth Study project. Participants were 80,928 school children(Grades 4–12; 39,747 boys, 41,181 girls; mean age = 13 years) and 935 physical education(PE) teachers who completed a study survey.Independent variables included both school-related factors(school-level PA support, availability of and access to PA facilities, and the duration of school PE classes) and community-related factors(the frequency of sports events, sports training opportunities, availability of sports clubs and organizations, and access to PA facilities). The dependent variable was the children's self-reported participation in MVPA. The data were analyzed,in 2017, via multilevel modeling.Results: PA support from school administrators was the only school-level factor significantly related to children's participation in MVPA.Children's perceptions of the frequency of community-sponsored sports events, availability of sports clubs and organizations, and convenient access to PA facilities were associated with a high level of MVPA participation. In regard to residency in urban and rural areas, children attending urban schools who perceived high availability of PA facilities were associated with a low level of participation in MVPA.Conclusion: School support for PA and community PA resources are associated with MVPA among Chinese school children. School PA facilities appear underutilized among urban schools as evidenced by low levels of MVPA among school children. | Lijuan Wang Yan Tang Jiong Luo | 2017 | Journal of Sport and Health Science2017，6，4： | 11 |
| 6 | Clinical risk score for invasive fungal diseases in patients with hematological malignancies undergoing chemotherapy:China Assessment of Antifungal Therapy in Hematological Diseases (CAESAR) study显示文摘Invasive fungal disease (IFD) is a major infectious complication in patients with hematological malignancies.In this study,we examined 4889 courses of chemotherapy in patients with hematological diseases to establish a training dataset (n=3500) by simple random sampling to develop a weighted risk score for proven or probable IFD through multivariate regression,which included the following variables: male patients,induction chemotherapy for newly diagnosed or relapsed disease,neutropenia,neutropenia longer than 10 days,hypoalbuminemia,central-venous catheter,and history of IFD.The patients were classified into three groups,which had low (0-10,~1.2%),intermediate (11-15,6.4%),and high risk (> 15,17.5%) of IFD.In the validation set (n=1389),the IFD incidences of the groups were ~1.4%,5.0%,and 21.4%.In addition,we demonstrated that antifungal prophylaxis offered no benefits in low-risk patients,whereas benefits were documented in intermediate (2.1% vs.6.6%,P=0.007) and high-risk patients (8.4% vs.23.3%,P=0.007).To make the risk score applicable for clinical settings,a pre-chemo risk score that deleted all unpredictable factors before chemotherapy was established,and it confirmed that anti-fungal prophylaxis was beneficial in patients with intermediate and high risk of IFD.In conclusion,an objective,weighted risk score for IFD was developed,and it may be useful in guiding antifungal prophylaxis. | Ling Wang Ying Wang Jiong Hu Yuqian Sun He Huang Jing Chen Jianyong Li Jun Ma Juan Li Yingmin Liang Jianmin Wang Yan Li Kang Yu Jianda Hu Jie Jin Chun Wang Depei Wu Yang Xiao Xiaojun Huang | 2019 | Frontiers of Medicine2019，13，3： | 10 |
| 7 | A brief history of the discovery of PXR and CAR as xenobiotic receptors显示文摘The nuclear receptors pregnane X receptor(PXR) and constitutive androstane receptor(CAR) were cloned and/or established as xenobiotic receptors in 1998.Due to their activities in the transcriptional regulation of phase I and phase II enzymes as well as drug transporters,PXR and CAR have been defined as the master regulators of xenobiotic responses.The discovery of PXR and CAR provides the essential molecular basis by which drugs and other xenobiotic compounds regulate the expression of xenobiotic enzymes and transporters.This article is intended to provide a historical overview on the discovery of PXR and CAR as xenobiotic receptors. | Jiong Yan Wen Xie | 2016 | Acta Pharmaceutica Sinica B2016，6，5： | 9 |
| 8 | Neuroprotective effect of baicalin on focal cerebral ischemia in rats显示文摘Baicalin, a flavonoid compound from the root of the herb Scutellaria baicalensis Georgi, has been widely used to treat patients with inflammatory disease. The aim of this study was to assess the efficacy of baicalin in a rat model of focal cerebral ischemia. Adult male Sprague-Dawley rat models of cerebral artery occlusion were established and then randomly and equally divided into three groups: ischemia(cerebral ischemia and reperfusion), valproic acid(cerebral ischemia and reperfusion + three intraperitoneal injections of valproic acid; positive control), and baicalin(cerebral ischemia and reperfusion + intraperitoneal injection of baicalin for 21 days). Neurological deficits were assessed using the postural reflex test and forelimb placing test at 3, 7, 14, and 21 days after ischemia. Rat cerebral infarct volume was measured using 2,3,5-triphenyltetrazolium chloride(TTC) staining method. Pathological change of ischemic brain tissue was assessed using hematoxylin-eosin staining. In the baicalin group, rat neurological function was obviously improved, cerebral infarct volume was obviously reduced, and the pathological impairment of ischemic brain tissue was obviously alleviated compared to the ischemia group. Cerebral infarct volume was similar in the valproic acid and baicalin groups. These findings suggest that baicalin has a neuroprotective effect on cerebral ischemia. | Jiong Dai Yong-Ming Qiu Zheng-Wen Ma Guo-Feng Yan Jing Zhou Shan-Quan Li Hui Wu Yi-Chao Jin Xiao-Hua Zhang | 2018 | Neural Regeneration Research2018，13，12： | 7 |
| 9 | Optimal b value of diffusion-weighted imaging on a 3.0T magnetic resonance scanner in Crohn's disease显示文摘AIM:To determine the optimal b value of diffusionweighted imaging for detecting active inflammation in Crohn's disease.METHODS:Thirty-one patients clinically diagnosed with active Crohn’s disease were referred for magnetic resonance examination.All patients were scanned on a3.0T magnetic resonance scanner using the same protocol involving four different b values(800,1500,2000and 2500 s/mm2).The diagnostic effect of diffusionweighted imaging was evaluated and compared with endoscopic findings.The diffusion-weighted image quality of four b value groups was evaluated and apparent diffusion coefficient was measured for both nor-mal and inflammatory intestinal segments.RESULTS:The contrast-to-noise ratio and signal-tonoise ratio were not satisfied when b value 2000 or2500 s/mm2 was adopted(36.52±14.95 vs 34.78±24.83,P>0.05;53.58±23.45 vs 47.58±29.67,P>0.05).The qualitative image quality was not enough to meet diagnostic requirement.No matter which b value was chosen,the apparent diffusion coefficient of inflammatory intestinal segments was significantly lower than that of normal intestinal segments(1.38±0.28 vs 2.00±0.38,P<0.01;1.09±0.20 vs 1.50±0.28,P<0.01;0.95±0.19 vs 1.34±0.28,P<0.01;0.88±0.14 vs 1.20±0.21,P<0.01).The lesion detection rate(90.32%),diagnostic sensitivity(81.18%)and specificity(95.10%)would be appropriate when b value 1500 s/mm2 was adopted.CONCLUSION:High b value is suitable for intestinal DW examination on a high field MR scanner. | Qi Feng Yun-Qi Yan Jiong Zhu Jin-Lu Tong Jian-Rong Xu | 2014 | World Journal of Gastroenterology2014，20，35： | 4 |
| 10 | PEA3 activates CXCR4 transcription in MDA-MB-231 and MCF7 breast cancer cells显示文摘(CXCR4 ) CXC chemokine 受体 4 是被显示了调停的房间表面受体包括肺,胸,肾,和前列腺的许多稳固的肿瘤的转移肿瘤。在这研究,我们发现 et 变体基因 4 的 overexpression (PEA3 ) 能在人的 MDA-MB-231 和 MCF-7 乳癌房间提高 CXCR4 mRNA 水平和 CXCR4 倡导者活动。PEA3 支持了 CXCR4 表示和乳癌转移。染色质 immunoprecipitation 试金证明 PEA3 能与 PEA3 表示向量在房间 transfected 绑在 CXCR4 倡导者。PEA3 siRNA 在 MDA-MB-231 和 MCF-7 房间稀释了 CXCR4 倡导者活动和 PEA3 的绑定到 CXCR4 倡导者。这些结果显示 PEA3 能激活 CXCR4 倡导者抄写并且支持乳癌转移。 | Shengmei Gu Li Chen Qi Hong Tingting Yan Zhigang Zhuang Qiaoqiao Wang Wei Jin Hua Zhu Jiong Wu | 2011 | Acta Biochimica et Biophysica Sinica2011，43，10： | 4 |
| 11 | Updating magnetic resonance imaging of small bowel:Imaging protocols and clinical indications显示文摘High soft tissue contrast resolution,acquisition of multi-planar images and the possibility to obtain functional information make magnetic resonance an interesting imaging technique to evaluate the small bowel disease.The absence of ionizing radiation is an important feature of magnetic resonance imaging(MRI) examinations because inflammatory diseases such as Crohn's disease(CD) are studied most frequently,which are prevalent among children and young adults.MRI,using modern equipment and a rigorous technical approach,can offer detailed morphologic information and functional data on the small bowel.This article discusses the MRI protocols for small bowel and the MR imaging findings of small bowel diseases,such as CD and small bowel neoplasms. | Jiong Zhu Jian-Rong Xu Hong-Xia Gong Yan Zhou | 2008 | World Journal of Gastroenterology2008，14，21： | 4 |
| 12 | Mechanism of energy limit equilibrium of rock burst in coal mine显示文摘随采矿深度的增加,在煤采矿上冲破的岩石的效果正在变得越来越明显,岩石爆炸机制变得越来越复杂。来自许多国家的学者提出了不同机制,但是没有人把合理解释给了冲破的岩石的机制。在这份报纸,基于精力理论,我们学习了矿岩石冲破了的煤的精力限制平衡(ELE ) 。有冲破的岩石的煤缝接被划分成精力限制平衡地区(ELEZ )(A) 和有弹性的地区(B) ;我们也决定了岩石爆炸发生的位置,包括煤缝接的房顶和地板;另外,我们导出在限制宽度和冲破的岩石的出现机制之间的 ELEZ 和数学关系的限制宽度:精力差别功能(EDF ) , w (x)= wj wp 一阶的衍生物 w (x) ,是不到 0。EDF 因此是 monotonically 减少的功能。精力差别功能的图也被决定,通过哪个我们分析了岩石的出现机制爆炸。 | Wang Jiong Yan Yubiao Jiang Zhengjun Qi Ping Chen Chen | 2011 | Mining Science and Technology2011，21，2： | 4 |
| 13 | Mudskipper interleukin-34 modulates the functions of monocytes/macrophages via the colony-stimulating factor-1 receptor 1显示文摘Interleukin-34(IL-34)is a novel cytokine that plays an important role in innate immunity and inflammatory processes by binding to the colonystimulating factor-1 receptor(CSF-1R).However,information on the function of IL-34 in fish remains limited.In the present study,we identified an IL-34 homolog from mudskippers(Boleophthalmus pectinirostris).In silico analysis showed that the mudskipper IL-34(BpIL-34)was similar to other known IL-34 variants in sequence and structure and was most closely related to an orange-spotted grouper(Epinephelus coioides)homolog.BpIL-34 transcripts were constitutively expressed in various tissues,with the highest level of expression found in the brain.Edwardsiella tarda infection significantly up-regulated the mRNA expression of BpIL-34 in the mudskipper tissues.The recombinant mature BpIL-34 peptide(rBpIL-34)was purified and used to produce anti-rBpIL-34 IgG.Western blot analysis combined with PNGase F digestion revealed that native BpIL-34 in monocytes/macrophages(MOs/MФs)was N-glycosylated.In vitro,rBpIL-34 treatment enhanced the phagocytotic and bactericidal activity of mudskipper MOs/MФs,as well as the mRNA expression of pro-inflammatory cytokines like tumor necrosis factorα(BpTNF-α)and BpIL-1βin these cells.Furthermore,the knockdown of mudskipper CSF-1R1(BpCSF-1R1),but not mudskipper BpCSF-1R2,significantly inhibited the rBpIL-34-mediated enhanced effect on MO/MФfunction.In conclusion,our results indicate that mudskipper BpIL-34 modulates the functions of MOs/MФs via BpCSF-1R1. | Hai-Yu Shen Yan Zhou Qian-Jin Zhou Ming-Yun Li Jiong Chen | 2020 | Zoological Research2020，41，2： | 3 |
| 14 | Risk factors for postoperative seromas in Chinese breast cancer patients显示文摘 | LIN Yan-ping YIN Wen-jin YAN Ting-ting ZHOU Li-heng DI Geng-hong WU Jiong SHEN Zhen-zhou SHAO Zhi-min LU Jin-song | 2011 | Chinese Medical Journal2011，，9： | 2 |
| 15 | Malignant fibrous histiocytoma of the bone in a traumatic amputation stump: A case report and review of the literature显示文摘BACKGROUND Malignant fibrous histiocytoma(MFH)is one of the most common soft tissue sarcomas among adults.It is characterized by large size,high grade,and biological aggressiveness.There are many reports of MFH after local stimulation,such as bone fracture,implants,and chronic osteomyelitis.In this paper,we report a patient who developed MFH 6 years after amputation,suggesting that wound healing and mechanical force play a role in the local stimulation of this disease.CASE SUMMARY A 66-year-old man complained of persistent pain in his residual mid-thigh.He had undergone amputation surgery due to a traffic accident 6 years prior.Physical examination showed tenderness but no abnormalities in appearance.Xray radiographs and magnetic resonance imaging supported the diagnosis of a tumor,and a biopsy confirmed that the lesion was MFH.The patient received neoadjuvant chemotherapy and left hip disarticulation.During the 6-mo followup,there were no symptoms of recurrence.CONCLUSION Postsurgery MFH has been reported before,and many studies have attributed it to the biological effects of implants.Our case report shows that this disease can develop without an implant and thus highlights the importance of local stimulation.The wound-healing process and mechanical force can both promote this tumor,but whether they directly cause MFH needs further investigation. | Ke-Yang Zhao Xu Yan Peng-Fei Yao Jiong Mei | 2021 | World Journal of Clinical Cases2021，9，26： | 1 |
| 16 | Contributions of the Visual Ventral Pathway to Long-Range Apparent Motion(视腹侧通路在长距离似动中的贡献)显示文摘 | Zhuo Yan Zhou Tian gang Rao Heng yi Jiong jiongWang Meng Ming Chen Ming Zhou Cheng and ChenLin | 2003 | SCIENCE2003，299，： | 1 |
| 17 | The Contribu- tion of 17beta - Hydroxysteroid Dehydrogenase Type 1 to the Estradiol - Estrone Ratio in Estrogen - Sensitive Breast Cancer Cells 显示文摘 | Chen -Yan Zhang Jiong Chen Da- Chuan Yin | 2012 | PLOS2012，7，29： | 1 |
| 18 | Floor heave in the west wing track haulage roadway of the Tingnan caol mine:mechanism and control显示文摘 | Wang jiong Guo Zhibiao Yan Yubiao | | 0，，03： | 1 |
| 19 | Fluorinated Graphene for Promoting Neuro‐Induction of Stem Cells显示文摘 | Yu Wang Wong Cheng Lee Kiran Kumar Manga Priscilla Kailian Ang Jiong Lu Yan Peng Liu Chwee Teck Lim Kian Ping Loh | 2012 | Adv Mater2012，，31： | 1 |
| 20 | T staging of rectal cancer: Accuracy of diffusion‐weighted imaging compared with T2 ‐weighted imaging on 3.0 tesla MRI显示文摘 | Qi Feng Yun Qi Yan Jiong Zhu Jian Rong XU | 2014 | Journal of Digestive Diseases2014，，： | 1 |
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