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| 1 | 果园风送喷雾精准控制方法研究进展显示文摘果园风送喷雾技术与装备正在朝着精准化和智能化方向发展。果园喷雾控制对象主要为喷施药量和风力供给量,二者需要协同精准调控,其按需调控的前提是果园靶标精准探测。该文从果园靶标探测方法、喷施药量控制方法、风力调控方法 3个方面对现有研究进展进行综述,阐述了基于光电感知、超声波传感、激光雷达、图像、光谱和电子鼻技术探测果树位置、冠层外形轮廓、冠层体积、冠层内部结构、枝叶稠密程度、病虫害程度等特征信息的技术方法;分析了喷施药量调控方法中管道总药量控制方法在管道设计、混药方式、药液流量控制策略方面技术和产品化上取得的巨大突破,以及喷头药量独立控制方法研究方面获得的大量成果;综述了果园风送喷雾风速风量需求理论原则、风场雾场建模方法、风力调控方法与调控装备研究进展,指出了其基本理论原则、建模调控方法等科学问题还有待深入探索。同时,还分析了目前研究在果园靶标探测方法、喷施药量调控方法和风送喷雾风力调控方法中面临的困难和挑战,主要包括冠层稠密程度和病虫害程度高效感知方法探索、靶标风力需求普适模型构建、风场建模风力按需调控方法研究和精准喷雾技术与系统集成开发。最后指出了果园风送喷雾精准控制方法未来发展方向:1)果园靶标冠层枝叶稠密程度和病虫害程度在线探测方法将成为新的研究热点;2)果园风送喷雾风速风量供给需求理论原则、风场快速模拟仿真和风力调控方法与装备是未来重要研究方向;3)随着高新科技的涌现,科研院所和公司有望在果园喷雾药量和风力调控系统优化设计及精准喷雾机系统集成研发方面获得更大发展。 | 翟长远 赵春江 Ning Wang John Long 王 秀 Paul Weckler 张海辉 | 2018 | 农业工程学报2018，34，10： | 61 |
| 2 | Potential Toxicological and Cardiopulmonary Effects of PM2,5 Exposure and Related Mortality:Findings of Recent Studies Published during 2003-2013显示文摘INTRODUCTION Air pollution has become a serious environmental issue owing to its diverse harmful effects on the physical and biological environment.According to the Environmental Protection Agency(EPA)and the World Health Organization(WHO)[1-2],air pollution affects millions of people worldwide.Hundreds of thousands of deaths each year and a range of diseases, | Mohammed O.A.Mohammed SONG Wei Wei MA Wan Li LI Wen Long LI Yi Fan Afed Ullah Khan Mohammed A.E.M.Ibrahim Osman Adam Maarouf Alshebli A Ahmed John J.Ambuchi | 2016 | Biomedical and Environmental Sciences2016，29，1： | 16 |
| 3 | Historic distribution and driving factors of human-caused fires in the Chinese boreal forest between 1972 and 2005显示文摘Aims The pattern and driving factors of forest fires are of interest for fire occurrence prediction and forest fire management.The aims of the study were:(i)to describe the history of human-caused fires by season and size of burned area over time;(ii)to identify the spatial patterns of human-caused fires and test for the existence of‘hotspots’to determine their exact locations in the Daxing’an mountains;(iii)to determine the driving factors that determine the spatial distribution and the possibility of human-caused fire occurrence.Methods In this study,K-function and Kernel density estimation were used to analyze the spatial pattern of human-caused fires.The analysis was conducted in s-plus and arcgIs environments,respectively.The analysis of driving factors was performed in SPSS 19.0 based on a logistic regression model.The variables used to identify factors that influence fire occurrence included vegetation types,meteorological conditions,socioeconomic factors,topography and infrastructure factors,which were extracted and collected through the spatial analysis mode of arcgIs and from official statistics,respectively.Important Findings The annual number of human-caused fires and the area burnt have declined since 1987 due to the implementation of a forest fire protection act.There were significant spatial heterogeneity and seasonal variations in the distribution of human-caused fires in the Daxing’an mountains.The heterogeneity was caused by elevation,distance to the nearest railway,forest type and temperature.a logistic regression model was developed to predict the likelihood of human-caused fire occurrence in the Daxing’an mountains;its global accuracy attained 64.8%.The model was thus comparable to other relevant studies. | Futao Guo John L.Innes Guangyu Wang Xiangqing Ma Long Sun Haiqing Hu Zhangwen Su | 2015 | Journal of Plant Ecology2015，8，5： | 10 |
| 4 | 果园风送喷雾机的改进设计与喷雾高度调控模型构建显示文摘【目的】针对第一代果园喷雾机存在的风箱角度不能电动控制且调节精度不高、传动装置设计欠合理和体积偏大等问题进行改进,并建立喷雾高度调控模型,为新一代果园喷雾机的设计提供参考。【方法】对喷雾机导流风箱的固定方式、传动方案和通过性能进行了改进,并通过喷雾沉积分布试验及数学方程拟合,建立沉积分布重心高度、喷雾宽度与风箱角度之间的数学模型。【结果】与改进前相比,该喷雾机不仅支持风箱角度电动精确调控,而且其理论功耗还减少了8%,长度尺寸减小了32.6%。风箱旋转角度对喷雾机尺寸影响的测试结果表明,旋转角度对风箱组宽度有一定的影响,旋转角度为最大值30°时风箱组宽度最大,为0.95m,但仍然小于喷雾机轮距1.0m;风箱旋转角度对喷雾机高度基本没有影响。改进后的喷雾机喷雾沉积分布试验表明,风箱与铅垂线夹角分别为0°,15°和30°时,喷雾沉积分布重心高度分别为1.14,1.55和2.20m,70.7%的药量分别垂直集中分布于0.72~1.56,1.15~1.94和1.71~2.69m,拟合得到的沉积分布重心高度、喷雾宽度和风箱角度之间的数学方程均为线性方程,其R2值分别为0.982和0.996。【结论】改进后喷雾机支持喷雾高度电动精确调节;所建立的喷雾高度智能调控模型可为果园喷雾机的改进完善提供支持。 | 翟长远 徐莎 John Long 李瀚哲 张波 朱瑞祥 | 2018 | 西北农林科技大学学报(自然科学版)2018，46，9： | 9 |
| 5 | Molecular evolution of the rice miR395 gene family显示文摘MicroRNAs (miRNAs) are 20-22 nucleotide non-coding RNAs that play important roles in plant and animal development. They are usually processed from larger precursors that can form stem-loop structures. Among 20 miRNA families that are conserved between Arabidopsis and rice, the rice miR395 gene family was unique because it was organized into compact clusters that could be transcribed as one single transcript. We show here that in fact this family had four clusters of total 24 genes. Three of these clusters were segmental duplications. They contained miR395 genes of both 120 bp and 66 bp long. However, only the latter was repeatedly duplicated. The fourth cluster contained miR395 genes of two different sizes that could be the consequences of intergenic recombination of genes from the first three clusters. On each cluster, both 1-duplication and 2-duplication histories were observed based on the sequence similarity between miR395 genes, some of which were nearly identical suggesting a recent origin. This was supported by a miR395 locus survey among several species of the genus Oryza, where two clusters were only found in species with an AA genome, the genome of the cultivated rice. A comparative study of the genomic organization of Medicago truncatula miR395 gene family showed significant expansion of intergenic spaces indicating that the originally clustered genes were drifting away from each other. The diverse genomic organizations of a conserved microRNA gene family in different plant genomes indicated that this important negative gene regulation system has undergone dramatic tune-ups in plant genomes. | Sreelatha GUDDETI De Chun ZHANG Ai Li LI Chuck H. LESEBERG Hui KANG Xiao Guang LI Wen Xue ZHAI Mitrick A. JOHNS Long MAO | 2005 | Cell Research2005，15，8： | 7 |
| 6 | Human ACE2-Functionalized Gold“Virus-Trap”Nanostructures for Accurate Capture of SARS-CoV-2 and Single-Virus SERS Detection显示文摘The current COVID-19 pandemic urges the extremely sensitive and prompt detection of SARS-CoV-2 virus.Here,we present a Human Angiotensin-converting-enzyme 2(ACE2)-functionalized gold“virus traps”nanostructure as an extremely sensitive SERS biosensor,to selectively capture and rapidly detect S-protein expressed coronavirus,such as the current SARS-CoV-2 in the contaminated water,down to the single-virus level.Such a SERS sensor features extraordinary 106-fold virus enrichment originating from high-affinity of ACE2 with S protein as well as“virus-traps”composed of oblique gold nanoneedles,and 109-fold enhancement of Raman signals originating from multi-component SERS effects.Furthermore,the identification standard of virus signals is established by machine-learning and identification techniques,resulting in an especially low detection limit of 80 copies mL^(−1) for the simulated contaminated water by SARS-CoV-2 virus with complex circumstance as short as 5 min,which is of great significance for achieving real-time monitoring and early warning of coronavirus.Moreover,here-developed method can be used to establish the identification standard for future unknown coronavirus,and immediately enable extremely sensitive and rapid detection of novel virus. | Yong Yang Yusi Peng Chenglong Lin Li Long Jingying Hu Jun He Hui Zeng Zhengren Huang Zhi-Yuan Li Masaki Tanemura Jianlin Shi John R.Lombardi Xiaoying Luo | 2021 | Nano-Micro Letters2021，13，7： | 6 |
| 7 | Charge‑Transfer Resonance and Electromagnetic Enhancement Synergistically Enabling MXenes with Excellent SERS Sensitivity for SARS‑CoV‑2 S Protein Detection显示文摘The outbreak of coronavirus disease 2019 has seriously threatened human health.Rapidly and sensitively detecting SARSCoV-2 viruses can help control the spread of viruses.However,it is an arduous challenge to apply semiconductor-based substrates for virus SERS detection due to their poor sensitivity.Therefore,it is worthwhile to search novel semiconductor-based substrates with excellent SERS sensitivity.Herein we report,for the first time,Nb2C and Ta2C MXenes exhibit a remarkable SERS enhancement,which is synergistically enabled by the charge transfer resonance enhancement and electromagnetic enhancement.Their SERS sensitivity is optimized to 3.0×10^6 and 1.4×10^6 under the optimal resonance excitation wavelength of 532 nm.Additionally,remarkable SERS sensitivity endows Ta2C MXenes with capability to sensitively detect and accurately identify the SARS-CoV-2 spike protein.Moreover,its detection limit is as low as 5×10^−9 M,which is beneficial to achieve real-time monitoring and early warning of novel coronavirus.This research not only provides helpful theoretical guidance for exploring other novel SERS-active semiconductor-based materials but also provides a potential candidate for the practical applications of SERS technology. | Yusi Peng Chenglong Lin Li Long Tanemura Masaki Mao Tang Lili Yang Jianjun Liu Zhengren Huang Zhiyuan Li Xiaoying Luo John RLombardi Yong Yang | 2021 | Nano-Micro Letters2021，13，3： | 3 |
| 8 | Epidemiology of prostatitis: new evidence for a world-wide problem显示文摘 | John N. Krieger Donald E. Riley Phaik Yeong Cheah Men Long Liong Kah Hay Yuen | 2003 | World Journal of Urology2003，，2： | 3 |
| 9 | Th1 cytokines promote T-cell binding to antigen-presenting cells via enhanced hyaluronan production and accumulation at the immune synapse显示文摘Hyaluronan(HA)production by dendritic cells(DCs)is known to promote antigen presentation and to augment T-cell activation and proliferation.We hypothesized that pericellular HA can function as intercellular‘glue’directly mediating T cell–DC binding.Using primary human cells,we observed HA-dependent binding between T cells and DCs,which was abrogated upon pre-treatment of the DCs with 4-methylumbelliferone(4-MU),an agent which blocks HA synthesis.Furthermore,T cells regulate HA production by DCs via T cell-derived cytokines in a T helper(Th)subset-specific manner,as demonstrated by the observation that cell-culture supernatants from Th1 but not Th2 clones promote HA production.Similar effects were seen upon the addition of exogenous Th1 cytokines,IL-2,interferon c(IFN-c)and tumor necrosis factor a(TNF-a).The critical factors which determined the extent of DC–T cell binding in this system were the nature of the pre-treatment the DCs received and their capacity to synthesize HA,as T-cell clones which were pre-treated with monensin,added to block cytokine secretion,bound equivalently irrespective of their Th subset.These data support the existence of a feedforward loop wherein T-cell cytokines influence DC production of HA,which in turn affects the extent of DC–T cell binding.We also document the presence of focal deposits of HA at the immune synapse between T-cells and APC and on dendritic processes thought to be important in antigen presentation.These data point to a pivotal role for HA in DC–T cell interactions at the IS. | Paul L Bollyky Stephen P Evanko Rebecca P Wu Susan Potter-Perigo S Alice Long Brian Kinsella Helena Reijonen Kelly Guebtner Brandon Teng Christina K Chan Kathy R Braun John A Gebe Gerald T Nepom Thomas N Wight | 2010 | Cellular & Molecular Immunology2010，7，3： | 3 |
| 10 | Exercise interventions for older adults: A systematic review of meta-analyses显示文摘Background:The evidence concerning which physical exercise characteristics are most effective for older adults is fragmented.We aimed to characterize the extent of this diversity and inconsistency and identify future directions for research by undertaking a systematic review of metaanalyses of exercise interventions in older adults.Methods:We searched the Cochrane Database of Systematic Reviews,PsycInfo,MEDLINE,Embase,CINAHL,AMED,SPORTDiscus,and Web of Science for articles that met the following criteria:(1)meta-analyses that synthesized measures of improvement(e.g.,effect sizes)on any outcome identified in studies of exercise interventions;(2)participants in the studies meta-analyzed were adults aged 65+or had a mean age of 70+;(3)meta-analyses that included studies of any type of exercise,including its duration,frequency,intensity,and mode of delivery;(4)interventions that included multiple components(e.g.,exercise and cognitive stimulation),with effect sizes that were computed separately for the exercise component;and(5)meta-analyses that were published in any year or language.The characteristics of the reviews,of the interventions,and of the parameters improved through exercise were reported through narrative synthesis.Identification of the interventions linked to the largest improvements was carried out by identifying the highest values for improvement recorded across the reviews.The study included 56 meta-analyses that were heterogeneous in relation to population,sample size,settings,outcomes,and intervention characteristics.Results:The largest effect sizes for improvement were found for resistance training,meditative movement interventions,and exercise-based active videogames.Conclusion:The review identified important gaps in research,including a lack of studies investigating the benefits of group interventions,the characteristics of professionals delivering the interventions associated with better outcomes,and the impact of motivational strategies and of significant others(e.g.,carers)on intervention delivery and outcomes. | Claudio Di Lorito Annabelle Long Adrian Byrne Rowan H.Harwood John R.F.Gladman Stefan Schneider Pip Logan Alessandro Bosco Veronika van der Wardt | 2021 | Journal of Sport and Health Science2021，10，1： | 3 |
| 11 | Skp2 dictates cell cycle-dependent metabolic oscillation between glycolysis and TCA cycle显示文摘Whether glucose is predomi nantly metabolized via oxidative phosphorylati on or glycolysis differs between quiesce nt versus proliferating cells,iincluding tumor cells.However,how glucose metabolism is coordinated with cell cycle in mammalian cells remains elusive.Here,we report that mammalian cells predominantly utilize the tricarboxylic acid(TCA)cycle in G1 phase,but prefer glycolysis in S phase.Mechanistically,coupling cell cycle with metabolism is largely achieved by timely destruction of IDH1/2,key TCA cycle enzymes,in a Skp2-dependent manner.As such,depleting SKP2 abolishes cell cycle-dependent fluctuation of IDH1 protein abundance,leading to reduced glycolysis in S phase.Furthermore,elevated Skp2 abundance in prostate cancer cells destabilizes IDH1 to favor glycolysis and subsequent tumorigenesis.Therefore,our study reveals a mechanistic link between two cancer hallmarks,aberrant cell cycle and addiction to glycolysis,and provides the underlying mechanism for the coupling of metabolic fluctuation with periodic cell cycle in mammalian cells. | Jing Liu Yunhua Peng Le Shi Lixin Wan Hiroyuki Inuzuka Jiangang Long Jianping Guo Jinfang Zhang Min Yuan Shuangxi Zhang Xun Wang Jing Gao Xiangpeng Dai Shozo Furumoto Lijun Jia Pier Paolo Pandolfic John M.Asara William G.Kaelin Jr. Jjankang Liu Wenyi Wei | 2021 | Cell Research2021，31，1： | 2 |
| 12 | Effects of acetic acid/acetic anhydride ratios on the properties of corn starch acetates显示文摘 | Cherif Ibrahima Khalil Diop Hai Long Li Bi Jun Xie John Shi | 2010 | Food Chemistry2010，，4： | 2 |
| 13 | Gamma generalized linear model to investigate the effects of climate variables on the area burned by forest fire in northeast China显示文摘The purpose of this study was to determine a suitable model for investigating the effects of climate factors on the area burned by forest fire in the Tahe forest region, Daxing'an Mountains, in northeast China. The response variables were the area burned by lightningcaused fire, human-caused fire, and total burned area. The predictor variables were nine climate variables collected from the local weather station. Three regression models were utilized, including multiple linear regression, loglinear model(log-transformation on both response and predictor variables), and gamma-generalized linear model.The goodness-of-fit of the models were compared based on model fitting statistics such as R^2, AIC, and RMSE. The results revealed that the gamma-generalized linear model was generally superior to both multiple linear regression model and log-linear model for fitting the fire data. Further,the best models were selected based on the criteria that the climate variables were statistically significant at a = 0.05.The gamma best models indicated that maximum wind speed, precipitation, and days that rainfall greater than0.1 mm had significant impacts on the area burned by the lightning-caused fire, while the mean temperature and minimum relative humidity were the main drivers of the burned area caused by human activities. Overall, the total burned area by forest fire was significantly influenced by days that rainfall greater than 0.1 mm and minimum relative humidity, indicating that the moisture condition of forest stands determine the burned area by forest fire. | Futao Guo Guangyu Wang John L. Innes Xiangqing Ma Long Sun Haiqing Hu | 2015 | Journal of Forestry Research2015，26，3： | 2 |
| 14 | Quantification of Nano‐ and Mesoscale Phase Separation and Relation to Donor and Acceptor Quantum Efficiency, J sc, and FF in Polymer:Fullerene Solar Cells显示文摘 | Wei Ma John R. Tumbleston Long Ye Cheng Wang Jianhui Hou Harald Ade | 2014 | Adv. Mater2014，，25： | 1 |
| 15 | Orga- noleptic characteristics of flavor materials显示文摘 | Gerald Mosciano John Long Carl Holmgren | 1996 | Perfumer and Flavorist1996，21，3： | 1 |
| 16 | The modeling,characterization,and design of monolit hic inductors for silicon RF IC's 显示文摘 | John R Long Miles A Copeland | 1997 | IEEE J of Solid-State Circuits1997，32，3： | 1 |
| 17 | A health literacy assessment of the National Epilepsy Foundation Web site显示文摘 | John O. Elliott Christine Charyton Lucretia Long | 2007 | Epilepsy and Behavior2007，，4： | 1 |
| 18 | Revolutionary Advances in the Management of Traumatic Wounds in the Emergency Department During the Last 40 Years: Part II显示文摘 | Richard F. Edlich George T. Rodeheaver John G. Thacker Kant Y. Lin David B. Drake Shelley S. Mason Courtney A. Wack Margot E. Chase Curt Tribble William B. Long Robert J. Vissers | 2010 | Journal of Emergency Medicine2010，，2： | 1 |
| 19 | The molecular conformation of silk fibroin regulates osteogenic cell behavior by modulating the stability of the adsorbed protein-material interface显示文摘Silk fibroin(SF)can be used to construct various stiff material interfaces to support bone formation.An essential preparatory step is to partially transform SF molecules from random coils toβ-sheets to render the material water insoluble.However,the influence of the SF conformation on osteogenic cell behavior at the material interface remains unknown.Herein,three stiff SF substrates were prepared by varying theβ-sheet content(high,medium,and low).The substrates had a comparable chemical composition,surface topography,and wettability.When adsorbed fibronectin was used as a model cellular adhesive protein,the stability of the adsorbed protein-material interface,in terms of the surface stability of the SF substrates and the accompanying fibronectin detachment resistance,increased with the increasingβ-sheet content of the SF substrates.Furthermore,(i)larger areas of cytoskeleton-associated focal adhesions,(ii)higher orders of cytoskeletal organization and(iii)more elongated cell spreading were observed for bone marrow-derived mesenchymal stromal cells(BMSCs)cultured on SF substrates with high vs.lowβ-sheet contents,along with enhanced nuclear translocation and activation of YAP/TAZ and RUNX2.Consequently,osteogenic differentiation of BMSCs was stimulated on highβ-sheet substrates.These results indicated that theβ-sheet content influences osteogenic differentiation of BMSCs on SF materials in vitro by modulating the stability of the adsorbed protein-material interface,which proceeds via protein-focal adhesion-cytoskeleton links and subsequent intracellular mechanotransduction.Our findings emphasize the role of the stability of the adsorbed protein-material interface in cellular mechanotransduction and the perception of stiff SF substrates with differentβ-sheet contents,which should not be overlooked when engineering stiff biomaterials. | Yanlin Long Xian Cheng John A.Jansen Sander G.C.Leeuwenburgh Jing Mao Fang Yang Lili Chen | 2021 | Bone Research2021，9，2： | 1 |
| 20 | Miscanthus for Renewable Energy Generation: European Union Experience and Projections for Illinois显示文摘 | Emily A. Heaton Stephen P. Long Thomas B. Voigt Michael B. Jones John Clifton-Brown | 2004 | Mitigation and Adaptation Strategies for Global Change2004，，4： | 1 |
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