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| 1 | Analysis of humidity-dependent adhesion between a probe tip and a surface显示文摘 | Li Yang Junhui Hu Huapeng Xiao Wenwen Quan | 2017 | Particuology2017，15，4： | 4 |
| 2 | Reduced grain chalkiness and its possible physiological mechanism in transgenic rice overexpressing L-GalLDH显示文摘Chalkiness is one of the key factors determining rice quality and price. Ascorbic acid(Asc) is a major plant antioxidant that performs many functions in plants. L-Galactono-1,4-lactone dehydrogenase(L-Gal LDH, EC1.3.2.3) is an enzyme that catalyzes the final step of Asc biosynthesis in plants. Here we show that the L-Gal LDH-overexpressing transgenic rice, GO-2,which has constitutively higher leaf Asc content than wild-type(WT) plants, exhibits significantly reduced grain chalkiness. Higher foliar ascorbate/dehydroascorbate(Asc/DHA)ratios at 40, 60, 80, and 100 days of plant age were observed in GO-2. Further investigation showed that the enhanced level of Asc resulted in a significantly higher ribulose-1,5-bisphosphate(Ru BP) carboxylase/oxygenase(Rubisco) protein level in GO-2 at 80 days. In addition, levels of abscisic acid(ABA) and jasmonic acid(JA) were lower in GO-2 at 60, 80, and100 days. The results we present here indicate that the enhanced level of Asc is likely responsible for changing redox homeostasis in key developmental stages associated with grain filling and alters grain chalkiness in the L-Gal LDH-overexpressing transgenic by maintaining photosynthetic function and affecting phytohormones associated with grain filling. | Le Yu Yonghai Liu Jianhua Tong Junhui Ding Ruozhong Wang Changlian Peng Langtao Xiao | 2015 | The Crop Journal2015，3，2： | 4 |
| 3 | Radio core dominance of Fermi/LAT-detected AGNs显示文摘We present a sample of 4388 AGNs with available radio core-dominance parameters—defined as the ratio of the core flux densities to the extended ones, R = S_(core)/S_(ext).—which includes 630 Fermi-detected AGNs from the fourth source catalog(4FGL) of the Fermi Large Area Telescope(Fermi/LAT);the rest are non-Fermi-detected AGNs. In our sample, 584 blazars are Fermi-detected and 1310 are not. The sample also contains other subclasses, such as Seyferts, Fanaroff-Riley I/II galaxies, and normal galaxies.We investigate various properties of the Fermi-detected and non-Fermi-detected AGNs by using core-dominance parameters,capitalizing on a previous study which showed that R is a good indicator of beaming. We then calculate radio spectral indices for the whole sample, and adopt γ-ray-photon indices for the Fermi AGNs from the 4FGL catalog to discuss the properties of different subclasses. We obtain a relation between the core-dominance parameters and the radio spectral indices for both Fermi and non-Fermi sources, assuming a two-component model in the radio band. Our previous study ruled out the assumption that the core-dominance parameters and radio spectral indices are quite different for different AGN subclasses. This holds not only for Fermi sources but also for non-Fermi sources. In particular, R is, on average, greater for the former AGNs than for the latter.In this study, we enlarge our sample with available values of R to 4388 AGNs, and the obtained conclusions are consistent with our previous study. We assume that the same two-component model holds for the γ-ray band as for the radio band, and therefore,adopt the same relation between the core-dominance parameters and the γ-ray-photon indices for Fermi AGNs. Our fitting results indicate that the γ-ray emissions of Fermi blazars originate mainly from the jet, and therefore, we conclude that the Fermi blazars are beamed. | ZhiYuan Pei JunHui Fan Denis Bastieri JiangHe Yang HuBing Xiao | 2020 | Science China(Physics,Mechanics & Astronomy)2020，63，5： | 2 |
| 4 | Synthesis of Ti(C,N) ultrafine powders by carbothermal reduction of TiO 2 derived from sol–gel process显示文摘 | Junhui Xiang Zhipeng Xie Yong Huang Hanning Xiao | 2000 | Journal of the European Ceramic Society2000，，7： | 1 |
| 5 | Junction plakoglobin regulates and destabilizes HIF2α to inhibit tumorigenesis of renal cell carcinoma显示文摘Background:Increased hypoxia-inducible factor 2α(HIF2α)activation is a common event in clear cell renal cell carcinoma(ccRCC)progression.However,the function and underlying mechanism of HIF2α in ccRCC remains uninvestigated.We conducted this study to access the potential link between junction plakoglobin(JUP)and HIF2αin ccRCC.Methods:Affinity purification and mass spectrometry(AP-MS)screening,glutathione-s-transferase(GST)pull-down and co-immunoprecipitation(Co-IP)assays were performed to detect the interacting proteins of HIF2α.Quantitative PCR(qPCR)and Western blotting were used to detect the expression of JUP in human ccRCC samples.Luciferase reporter assays,chromatin immunoprecipitation(ChIP),cycloheximide chase assays,and ubiquitination assays were conducted to explore the regulation of JUP on the activity of HIF2α.Cell Counting Kit-8(CCK-8)assays,colony formation assays,transwell assays,and xenograft tumor assays were performed to investigate the effect of JUP knockdown or overexpression on the tumorigenicity of renal cancer cells.Results:We identified JUP as a novel HIF2α-binding partner and revealed an important role of JUP in recruiting von Hippel-Lindau(VHL)and histone deacetylases 1/2(HDAC1/2)to HIF2α to regulate its stability and transactivation.JUP knockdown promoted and overexpression suppressed the tumorigenicity of renal cell carcinoma in vitro and in vivo.Importantly,the low expression of JUP was found in clinical ccRCC samples and correlated with enhanced hypoxia scores and poor treatment outcomes.Conclusion:Taken together,these data support a role of JUP in modulating HIF2α signaling during ccRCC progression and identify JUP as a potential therapeutic target. | Ke Chen Jin Zeng Yi Sun Wei Ouyang Gan Yu Hui Zhou Yangjun Zhang Weimin Yao Wei Xiao Junhui Hu Jinchun Xing Kefeng Xiao Lily Wu Zhiqiang Chen Zhangqun Ye Hua Xu | 2021 | Cancer Communications2021，41，4： | 1 |
| 6 | Strength Degradation of Wood Members Based on the Correlation of Natural and Accelerated Decay Experiments显示文摘An accelerated decay test and a natural decay test were conducted synchronically to explore the strength degradation of decaying wood members under long-term exposure to natural environment.A natural decay test was carried out to measure the bending strength,compressive strength parallel to grain and modulus of elasticity of the wood members,with 6 groups of specimens decayed in natural environment for 3 to 18 months respectively.To compare with corresponding decay test,in which 6 other groups of specimens were measured under accelerated conditions.The experimental data collected were evaluated by Pearson productmoment for the correlation.The results indicate that the mechanical properties of the accelerated decay were highly correlated with those in natural environment,both of which decreased in the same trend.Under the given test conditions,the mean value of the accelerated decay test data were curve-fitted to achieve the time-dependent degradation model of the bending strength,the compressive strength parallel to grain,as well as the modulus of elasticity.Due to the high correlation,the acceleration shift factors(ASF)of the two tests were derived,where the bending strength of 2.934,the compressive strength parallel to grain of 2.519 and the elastic modulus of 2.346 were employed to formulate the strength degradation models in the long-term natural environment.The results verify that the exponential functionσ=σ0e^(-βt)enables to exactly capture the degradation of the mechanical properties of wood members decayed in natural environment. | Xueliang Wang Qiangang Xu Xiuxin Wang Junhui Guo Wancheng Cao Chun Xiao | 2020 | Journal of Renewable Materials2020，8，5： | 1 |
| 7 | Satellite-based Estimation of Evapotranspiration of anOld-growth Temperate Mixed Forest显示文摘 | Zhang Junhui Hu Yanling Xiao Xiangming | 2009 | Agricultural and Forest Meteorology2009，149，11： | 1 |
| 8 | Resveratrol inhibits high glucose induced collagen upregulation in cardiac fibroblasts through regulating TGF-β1–Smad3 signaling pathway显示文摘 | Junhui Liu Xiaozhen Zhuo Weimin Liu Zhaofei Wan Xiao Liang Shanshan Gao Zuyi Yuan Yue Wu | 2015 | Chemico-Biological Interactions2015，，： | 1 |
| 9 | Weather index insurance for wind energy显示文摘As China vigorously promotes the development of new energy,photovoltaic power curtailment and wind power curtailment have been effectively resolved.At the same time,the yield from new energy power generation is becoming an important factor that affects the scale of investment in new energy.This paper focuses on the weather risks faced by wind power producers.By studying current research on weather index insurance in China and abroad,the functions and design methods for weather index insurance have been clarified.In addition,the feasibility of wind-power generation index insurance is discussed.The calculation methods for wind power generation index and the weather index insurance pricing methods for wind power enterprises are proposed.A weather index insurance model for wind power generation was established.The rationality and feasibility of the weather index insurance model proposed in this paper were verified using data from an existing power plant.The simulation results show that wind power enterprises can effectively avoid economic losses caused by weather risks through weather index insurance. | Xiao Han Guoxing Zhang Yixiang Xie Jiaxuan Yin Haiming Zhou Yunxi Yang Junhui Li Wenlei Bai | 2019 | Global Energy Interconnection2019，2，6： | 1 |
| 10 | Overexpression of CfPIP1-1,CfPIP1-2,and CfPIP1-4 genes of Catalpa fargesii in transgenic Arabidopsis thaliana under drought stress显示文摘Catalpa fargesii is an important economic tree species used for furniture and timber production because of its high density and hardness.Its survival and growth are severely aff ected and primarily limited by drought stress.Thus,to better understand the mechanism of drought resistance in C.fargesii,we used qRT-PCR to reveal signifi cantly diff erent expression of three plasma membrane intrinsic protein genes:CfPIP1-1,CfPIP1-2 and CfPIP1-4.We then cloned their full-length cDNA sequences and characterized the encoded proteins.We analyzed the genes phylogenetically and predicted conserved motifs,domains,and secondary and tertiary structures.To verify the function ofthe CfPIP1 genes further,we ectopically expressed CfPIP1 transgenes in Arabidopsis thaliana.The results showed that CfPIP1-1,CfPIP1-2 and CfPIP1-4 had several characteristics of aquaporins.The transgenic plants grew better than the WT plants did under drought stress,and overexpression of the CfPIP1 genes increased the plant water content and resistance to drought.Thus,CfPIP1-1,CfPIP1-2 and CfPIP1-4 of C.fargesii play key roles in regulating the intracellular and extracellular water balance and in mediating the plant response to drought. | Wenjun Ma Yao Xiao Yuan Li Pan Hu Zhi Wang Guijuan Yang Junhui Wang | 2021 | Journal of Forestry Research2021，32，1： | 1 |
| 11 | Comparison between Fermi detected and non-Fermi detected superluminal sources显示文摘Active galactic nuclei(AGNs) have been attracting research attention due to their special observable properties. Specifically,a majority of AGNs are detected by Fermi-LAT missions, but not by Fermi-LAT, which raises the question of weather any differences exist between the two. To answer this issue, we compile a sample of 291 superluminal AGNs(189 FDSs and 102 nonFDSs) from available multi-wavelength radio, optical, and X-ray(or even γ-ray) data and Doppler factors and proper motion(μ)(or apparent velocity(βapp));calculated the apparent velocity from their proper motion, Lorentz factor(Γ), viewing angle(Ф) and co-moving viewing angle(Фco) for the sources with available Doppler factor(δ);and performed some statistical analyses for both types. Our study indicated that(1) in terms of average values, FDSs have higher proper motions(μ), apparent velocities(βapp),Doppler factor(δ), Lorentz factor(Γ), and smaller viewing angle(Ф). Nevertheless, there is no clear difference in co-moving viewing angles(Ф∞). The results reveal that FDSs show stronger beaming effect than non-FDSs.(2) In terms of correlations:1) both sources show positive, mutually correlated fluxes, which become closer in de-beamed fluxes;2) with respect to apparent velocities and γ-ray luminosity, there is a tendency for the brighter sources to have higher velocities;3) with regard to viewing angle and observed γ-ray luminosity, logФ=-(0.23 ± 0.04)log Lγ+(11.14 ± 1.93), while for the co-moving viewing angle and the intrinsic γ-ray luminosity, logФ∞=(0.09 ± 0.01)log Lγ^in-(1.73 ± 0.48). These correlations show that the luminous γ-ray sources have smaller viewing angles and a larger co-moving viewing angle, which indicate a stronger beaming effect in γ-ray emissions. | HuBing Xiao JunHui Fan JiangHe Yang Yi Liu YuHai Yuan Jun Tao Denise Costantin YuTao Zhang ZhiYuan Pei LiXia Zhang WenXin Yang | 2019 | Science China(Physics,Mechanics & Astronomy)2019，62，12： | 1 |
| 12 | Biochar pyrolyzed at low temperature enhanced acidophilous plant growth by promoting rhizospheric microbes in a slightly alkaline urban soil显示文摘Biochar has been considered as a potential way to enhance acidophilous plant growth in alkaline soils.However,whether such enhancements are closely linked with biochar pyrolysis temperature and its improvements in rhizospheric soil fertility and microbial activities remains largely unknown.We performed a pot experiment to investigate changes in azalea(Rhodo-dendron)morphology and physiology,as well as its rhizosphere soil chemical and biological properties in a slightly alkaline urban soil under the amendment of biochars that pyrolyzed at three temperatures(i.e.,350,550 and 700°C).Our results showed that the effects of biochars on plant growth and soil properties depended on pyrolysis temperature.In comparison with the non-amended control,350 and 550°C biochars showed significant promotions on the azalea growth in terms of photosynthetic characteristics,biomass,root morphology,and N and P uptake.Whereas,700°C biochar showed an inhibi-tion effect on them.350°C biochar decreased soil pH and increased soil available P and K contents and the activities ofα-glucosidase,N-β-glucosaminidase,phosphatase and sulfatase.In addition,350°C biochar significantly enhanced bacterial 16S rRNA and fungal 18S rRNA gene abundances in the rhizosphere soil of azalea and mycorrhizal infection.Correlation analysis indicated that soil pH,available nutrients and fungal abundance had positive associations with the enhanced plant growth parameters.Therefore,our findings suggest that biochar produced at low temperature could be a feasible strategy for enhancing acidophilous azalea growth and improving urban soil quality. | Huimin Zhou Xiaoying Li Chang Li Lisi He Xiaoqing Liu Zheng Xiao Xiaobo Sun Gaoling Shi Jiale Su Junhui Chen | 2021 | Biochar2021，3，4： | 1 |
| 13 | Allelic variation in the coumarate 3-hydroxylase gene associated with wood properties of Catalpa fargesii Bur.显示文摘Coumarate 3-hydroxylase(C3h)genes participate in the synthesis of lignin and may affect the properties of wood that are important for its commercial value.A better understanding of the natural variation in C3h genes and their associations to wood properties is required to effectively improve wood quality.We used a candidate gene-based association mapping approach to identify CfC3h allelic variants associated with traits that affect the wood properties of Catalpa fargesii.We first isolated the full-length CfC3h cDNA(1825 bp),which was expressed at relatively high levels in xylem according to real time-polymerase chain reaction.In totally,17 common single-nucleotide polymorphisms(minor allele frequency>5%)were identified through cloning and sequencing the CfC3h locus from a mapping population(including 88 unrelated natural C.fargesii individuals collected from main distribution area).Nucleotide diversity and linkage disequilibrium(LD)in CfC3h indicate that CfC3h has low nucleotide diversity(π_(t)=0.0031 andθ_(w)=0.0103)and relatively low LD(within 1800 bp;r^(2)≥0.1).An association analysis identified eight common single-nucleotide polymorphisms(SNPs)(false discovery rate,Q<0.10)and ten haplotypes(Q<0.10)associated with wood properties,explaining 4.92-12.09%of the phenotypic variance in an association population consisted of 125 unrelated natural individuals(The 88 individuals from the mapping population were comprised in the association population).Our study would provide new insight into C3h gene affecting wood quality,and the SNP markers identified would have potential applications in marker-assisted breeding in the future. | Nan Lu Fang Mei Zhi Wang Nan Wang Yao Xiao Lisheng Kong Guanzheng Qu Wenjun Ma Junhui Wang | 2021 | Journal of Forestry Research2021，32，6： | 1 |
| 14 | Selective separation of iron and scandium from Bayer Sc-bearing red mud显示文摘In this study,we investigated the separation of iron and scandium from Sc-bearing red mud.The red mud object of our study contained 31.11 wt%total iron(TFe),0.0045 wt%Sc,hematite(Fe_(2)O_(3))and ferrosilite(FeO·SiO_(2))as the main Fe-bearing minerals.The Sc-bearing red mud was treated by a novel deep reduction roasting and magnetic separation process that includes the addition of coke and CaO to extract Fe and enriching Sc from the Sc-bearing red mud.The addition of coke and CaO enhances the transformation of hematite(Fe_(2)O_(3))to metallic iron(Fe~0)and magnetite(Fe_(3)O_(4))as well as the transformation of ferrosilite into metallic iron(Fe~0).The test results show that utilizing the new process a Fe concentrate with a TFe content of 81.22 wt%and Fe recovery of 92.96%was obtained.Furthermore,magnetic separation tailings with Sc content of 0.0062 wt%and Sc recovery of 98.65%were also obtained.The test results were achieved under the following process conditions:roasting temperature of 1373 K,roasting time of 45 min,calcium oxide dosage of 20 wt%,coke dosage of 25 wt%,grinding fineness of90%<0.04 mm,and magnetic field intensity of 0.24 T.The major minerals in the Fe concentrate are metallic iron(Fe~0)and magnetite(Fe_(3)O_(4)).The main minerals in the magnetic separation tailings with a low TFe content of 2.62%are CaO·SiO_(2),Na_(2)O·SiO_(2),FeO·SiO_(2),Ca_(3)Fe_(2)Si_(3)O_(12),CaAl_(2)SiO_6 and CaFe(SiO_(3))_(2). | Junhui Xiao Kai Zou Nanlan Zhong Deqiang Gao | 2023 | Journal of Rare Earths2023，41，7： | 0 |
| 15 | Electro-mechanical offset measurements of beam position monitors显示文摘Purpose The absolute beam position measurement in the booster and storage ring of the high energy photon source(HEPS)requires the offset between the electrical and mechanical centers of the beam position monitor(BPM).Method Traditionally,an RF signal is sent to an antenna or stretched wire aligned with the vacuum chamber,and the signal at each electrode is measured.Conversely,a replacement method using a vector network analyzer,which was proposed by Lambertson,does not involve mechanical alignment and can be used for electrical offset determination.Results and conclusions The electro-mechanical offsets of booster BPMs of the HEPS were measured using the Lambertson method.The result shows good agreement with the stretched wire method within a 30μm error. | Jun He Yanfeng Sui Yong Li Yaoyao Du Linda Yu Junhui Yue Jianshe Cao Xujian Wang Zhe Duan Ouzheng Xiao | 2023 | Radiation Detection Technology and Methods2023，7，2： | 0 |
| 16 | Lime Assisted Cyanide Leaching of Refractory Gold Ores from Ajialongwa Mine显示文摘Heap leaching is a promising, less costly, alternative technology for processing low grade gold ores compared with traditional, energy intensive processes (e.g. autoclave/tank leaching). This research investigated the effectiveness of lime for enhancing gold leaching rates of gold ores from ajialongwa gold mine in china. Column and heaping experiments were performed using cyanide leaching solutions at pH=10, with and without lime (CaO). The presence of lime greatly increased gold leaching rates. Column leaching experiments showed without the addition of lime, there was 35.2% of gold leached. The addition of lime resulted in the release of 50.56% gold. Lime assisted cyanide of refractory gold was proved by heap leaching experiments. | FU Kaibin WANG Zheng XIAO Junhui LUO Deqiang | 2013 | 矿物学报2013，33，S1： | 0 |
| 17 | Status of transjugular intrahepatic portosystemic shunt for portal hypertension in China:A national survey analysis显示文摘Aim:The transjugular intrahepatic portosystemic shunt(TIPS)procedure has been performed in China for 30 years,but our understanding of the status and difficulties associated with the use of TIPS for portal hypertension is incomplete.This study aims to investigate the current situation of the use of TIPS for portal hypertension,which should aid the development of TIPS in China.Methods:This study involved a questionnaire survey,initiated by the China Portal Hypertension Alliance(CHESS)to investigate the use of TIPS for portal hypertension in China.Questionnaires were released on the Internet between August 16,2022 and September 16,2022.Detailed information was collected from 545 hospitals contracted by the CHESS in China,which performed TIPS surgery in 2021.Results:The 545 hospitals covers the majority of hospitals in China that conduct TIPS intervention.In the survey,a total of 13,527 TIPS interventions were carried out with 94.1%(498/545)of them had a system of routine follow‐up after TIPS.The majority(42.6%[232/545])believed that the main indication of TIPS was the control of acute bleeding.Overall,48.1%(262/545)carried out early or pre‐emptive TIPS,53.0%(289/545)carried out TIPS for cavernous transformation of the portal vein,and 81.0%(441/545)chose routine embolization of collateral circulation during operation.Most used coils(97.0%[475/490])and biological glue(72.0%[353/490])as embolic materials,and 78.5%(428/545)routinely performed intraoperative portal pressure gradient measurements.When selecting TIPS stents,57.1%(311/545)chose viator‐specific stents,and 57.2%(312/545)chose conventional anticoagulation after TIPS.Conventional anticoagulation after TIPS is over a time interval of 3–6 months(55.4%[173/312]).The limitation of TIPS surgery is mainly its cost(72.3%[394/545])and insufficient understanding of the procedure by doctors in other related departments(77.4%[422/545]).Most of the hospital teams accept the use of domestic instruments in TIPS surgery(92.7%[505/545]).Conclusions:This survey shows that TIPS is an essential part of the treatment of portal hypertension in China.TIPS is widely used in Chinese patients with portal hypertension,and this survey presents a more comprehensive picture of the options and difficulties encountered in the implementation of TIPS.In the future,it is necessary to promote TIPS technology and further standardize surgical indications,routine operations,and instrument application. | Haibo Shao Xinwei Han Jianbo Zhao Junhui Sun Zhuting Fang Bin Xiong Xiaoli Zhu Weixin Ren Min Yuan Shiping Yu Meng Niu Weifu Lv Xueqiang Zhang Chunqing Zhang Lei Li Xuefeng Luo Yusheng Song Yilong Ma Tong Dang Hua Xiang Yun Jin Hui Xue Guiyun Jin Xiao Li Jiarui Li Shi Zhou Changlu Yu Song He Lei Yu Hongmei Zu Jun Ma Yanming Lei Ke Xu Xiaolong Qi | 2023 | Portal Hypertension & Cirrhosis2023，2，1： | 0 |
| 18 | Mesenchymal stem cell-derived exosomes: Versatile nanomaterials for skin wound treatment显示文摘Accumulating studies reveal that mesenchymal stem cells(MSCs)promote skin wound healing mainly through the paracrine effects.Exosomes,one of the crucial paracrine mediators in wound healing,are cell-derived nanosized membranous vesicles containing diverse bioactive cargoes.With the potent ability of modulating skin cell behaviors,MSC-derived exosomes(MSC-Exos)are regarded as a promising nanomaterial for regenerative wound therapy.Under hostile conditions,MSC-Exos are efficient in protecting skin cells from severe damage and restoring their function.According to recent studies,MSC-Exos possess remarkable pro-healing effects in a variety of skin wounds,typically resulting in increased wound closure,inhibited scar tissue formation,and better restoration of skin function.To further enhance the therapeutic potential of MSC-Exos,the development of applicable pretreatment strategies and the optimization of exosome delivery are under intensive investigation.Herein,we summarize current research progress of MSC-Exos for skin wound treatment,with an emphasis on the biological effects of these nanovesicles,the repair mechanisms,and future challenges in clinical translation. | Yuzhen Xiao Hexi Li Junhui Zhang Songyun Yang Chunsen Zhang Yizhou Huang Xin Tang Huiqi Xie | 2024 | Nano Research2024，17，4： | 0 |
| 19 | Generation of functional oligopeptides that promote osteogenesis based on unsupervised deep learning of protein IDRs显示文摘Deep learning(DL)is currently revolutionizing peptide drug development due to both computational advances and the substantial recent expansion of digitized biological data.However,progress in oligopeptide drug development has been limited,likely due to the lack of suitable datasets and difficulty in identifying informative features to use as inputs for DL models.Here,we utilized an unsupervised deep learning model to learn a semantic pattern based on the intrinsically disordered regions of~171 known osteogenic proteins.Subsequently,oligopeptides were generated from this semantic pattern based on Monte Carlo simulation,followed by in vivo functional characterization.A five amino acid oligopeptide(AIB5P)had strong bone-formation-promoting effects,as determined in multiple mouse models(e.g.,osteoporosis,fracture,and osseointegration of implants).Mechanistically,we showed that AIB5P promotes osteogenesis by binding to the integrinα5 subunit and thereby activating FAK signaling.In summary,we successfully established an oligopeptide discovery strategy based on a DL model and demonstrated its utility from cytological screening to animal experimental verification. | Mingxiang Cai Baichuan Xiao Fujun Jin Xiaopeng Xu Yuwei Hua Junhui Li Pingping Niu Meijing Liu Jiaqi Wu Rui Yue Yong Zhang Zuolin Wang Yongbiao Zhang Xiaogang Wang Yao Sun | 2022 | Bone Research2022，10，2： | 0 |
| 20 | Understanding the growth mechanisms of metal-based core–shell nanostructures revealed by in situ liquid cell transmission electron microscopy显示文摘Metal-based core-shell nanostructures have garnered enduring interest due to their unique properties and functionalities.However,their growth and transformation mechanisms in liquid media remain largely unknown because they lack direct observation of the dynamic growth process with high spatial and temporal resolution.Developing the in situ liquid cell transmission electron microscopy(TEM)technique offers unprecedented real-time imaging and spectroscopy capabilities to directly track the evolution of structural and chemical transformation of metal-based core–shell nanostructures in liquid media under their working condition.Here,this review highlights recent progress in utilizing in situ liquid cell TEM characterization technique in investigating the dynamic evolution of material structure and morphology of metal-based core–shell nanostructures at the nano/atomic scale in real-time.A brief introduction of the development of liquid cells for in situ TEM is first given.Subsequently,recent advances in in situ liquid cell TEM for the fundamental study of growth mechanisms of metal based core–shell nanostructures are discussed.Finally,the challenge and future developments of metalbased core–shell nanostructures for in situ liquid cell TEM are proposed.Our review is anticipated to inspire ongoing interest in revealing unseen growth dynamics of core–shell nanostructures by in situ liquid cell TEM technique. | Junyu Zhang Bensheng Xiao Junhui Zhao Miao Li Haichen Lin Zewen Kang Xianwen Wu Haodong Liu Dong-Liang Peng Qiaobao Zhang | 2022 | Journal of Energy Chemistry2022，31，8： | 0 |
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