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| 1 | Research progresses on Cherenkov and transit-time high-power microwave sources at NUDT显示文摘Research progresses on Cherenkov and transit-time high-power microwave(HPM)sources in National University of Defense Technology(NUDT)of China are presented.The research issues are focused on the following aspects.The pulse-shortening phenomenon in O-type Cerenkov HPM devices is suppressed.The compact coaxial relativistic backward-wave oscillators(RBWOs)at low bands are developed.The power efficiency in M-Type HPM tubes without guiding magnetic field increased.The power capacities and power efficiencies in the triaxial klystron amplifier(TKA)and relativistic transit-time oscillator(TTO)at higher frequencies increased.In experiments,some exciting results were obtained.The X-band source generated 2 GW microwave power with a pulse duration of 110 ns in 30 Hz repetition mode.Both L-and P-band compact RBWOs generated over 2 GW microwave power with a power efficiency of over 30%.There is approximately a 75% decline of the volume compared with that of conventional RBWO under the same power capacity conditions.A 1.755 GHz MILO produced 3.1 GW microwave power with power efficiency of 10.4%.A 9.37 GHz TKA produced the 240 MW microwave power with the gain of 34 dB.A 14.3 GHz TTO produced 1 GW microwave power with power efficiency of 20%. | Jiande Zhang Xingjun Ge Jun Zhang Juntao He Yuwei Fan Zhiqiang Li Zhenxing Jin Liang Gao Junpu Ling Zumin Qi | 2016 | Matter and Radiation at Extremes2016，1，3： | 7 |
| 2 | Genomic landscapes of Chinese sporadic autism spectrum disordersrevealed by whole-genome sequencing显示文摘Autism spectrum disorder (ASD) is a neurodevelopmental disorder with considerable clinical and genetic heterogeneity.In this study,we identified all classes of genomic variants from whole-genome sequencing (WGS) dataset of 32 Chinese trios with ASD,including de novo mutations,inherited variants,copy number variants (CNVs) and genomic structural variants.A higher mutation rate (Poisson test,P<2.2×10^(-16)) in exonic (1.37×10^(-8)) and 3'-UTR regions (1.42×10^(-8)) was revealed in comparison with that of whole genome (1.05×10^(-8)).Using an integrated model,we identified 87 potentially risk genes (P<0.01) from 4832 genes harboring various rare deleterious variants,including CHD8 and NRXN2,implying that the disorders may be in favor to multiple-hit.In particular,frequent rare inherited mutations of several microcephaly-associated genes (ASPM,WDR62,and ZNF335)were found in ASD.In chromosomal structure analyses,we found four de novo CNVs and one de novo chromosomal rearrangement event,including a de novo duplication of UBE3A-containing region at 15q11.2-q13.1,which causes Angelman syndrome and microcephaly,and a disrupted TNR due to de novo chromosomal translocation t (1;5) (q25.1;q33.2).Taken together,our results suggest that abnormalities of centrosomal function and chromatin remodeling of the microcephaly-associated genes may be implicated in pathogenesis of ASD.Adoption of WGS as a new yet efficient technique to illustrate the full genetic spectrum in complex disorders,such as ASD,could provide novel insights into pathogenesis,diagnosis and treatment. | Jinyu Wu Ping Yu Xin Jin Xiu Xu Jinchen Li Zhongshan Li Mingbang Wang Tao Wang Xueli Wu Yi Jiang Wanshi Cai Junpu Mei Qingjie Min Qiong Xu Bingrui Zhou Hui Guo Ping Wang Wenhao Zhou Zhengmao Hu Yingrui Li Tao Cai Yi Wang Kun Xia Yong-Hui Jiang Zhong Sheng Sun | 2018 | Journal of Genetics and Genomics2018，45，10： | 3 |
| 3 | Energy measurement system of a large-aperture high power laser experiment platform显示文摘An energy measurement system in a large-aperture high power laser experiment platform is introduced. The entire measurement system includes five calorimeters, which carry out the energy measurement of the fundamental frequency before the frequency conversion unit, remaining fundamental frequency, remaining second-harmonics, third-harmonics,as well as the energy balance measurement after the frequency conversion unit. Combinational indirect calibration and direct calibration are employed to calibrate the sampling coefficients of the calorimeters. The analysis of the data showed that, regarding the energy balance coefficients, combinational calibration approach gives a higher precision, and leads to an energy balance with 1%; and regarding the energy sampling coefficients for the various wavelengths after the frequency conversion, the results from direct and combinational calibration are consistent. The uncertainties for all energy sampling coefficients are within 3%, which guarantees the reliability of the energy measurement for the laser facility. | Yanwen Xia Yue Liang Sen Li Junpu Zhao Zhitao Peng Hongguang Li Hua Liu Zhihong Sun Kuixing Zheng Xiaofeng Wei | 2013 | High Power Laser Science and Engineering2013，1，Z1： | 2 |
| 4 | Fiber Bragg Grating Strain Sensors for Marine Engineering显示文摘 | Tingting WANG Zilin YUAN Yuan GONG Yu WU Yunjiang RAO Lili WEI Peng GUO Junpu WANG Fu WAN | 2013 | Photonic Sensors2013，3，3： | 2 |
| 5 | Genome-wide identification and expression analysis of NIN-like Protein(NLP)genes reveals their potential roles in the response to nitrate signaling in watermelon显示文摘To balance the relationship between high yield and low nitrogen supply,the nitrogen utilization efficiency of watermelon needs to be improved urgently.Nodule inception-like Protein(NLP)transcription factors play a key node role in nitrate response and growth and development of plant,however,comprehensive analysis of the NLP gene family in watermelon is unclear.This study explored the functional classification,evolutionary characteristics,and expression profile of the ClNLP gene family.Three ClNLPs were categorized into three groups according to their gene structure and phylogeny.All of them contained the conserved RWP-RK and PB1 domains.Evolutionary analysis of ClNLPs revealed that ClNLP1 and ClNLP3 underwent strong purified selection.In addition,cis-acting elements related to plant hormones and abiotic stresses were present in the ClNLP promoter.According to tissue-specific analysis ClNLP was widely expressed in roots,stems,leaves,flowers and fruits,and ClNLP1 was significantly induced in the roots of different nitrogen utilization varieties under different nitrate nitrogen supply.The SRTING functional protein association network suggested that ClNLP1 is associated with most genes,such as NRT1.1,NRT2.1,NIA1,and NIR1,and the dual-luciferase reporter assay found that ClNLP1 positively regulates the expression of ClNRT2.1.We speculated that ClNLP1 might play a central role in regulating the response of watermelon to nitrate nitrogen. | Gaopeng Yuan Dexi Sun Yifan Wang Guolin An Weihua Li Wenjing Si Junpu Liu Yingchun Zhu | 2022 | Horticultural Plant Journal2022，8，5： | 2 |
| 6 | Downregulation of Beclin1 and Impairment of Autophagy in a Small Population of Colorectal Cancer显示文摘 | Zhihong Chen Yanchun Li Chi Zhang Hongmei Yi Chang Wu Junpu Wang Yuwu Liu Jieqiong Tan Jifang Wen | 2013 | Digestive Diseases and Sciences2013，，10： | 2 |
| 7 | Analysis on Development Pathway of Farmer Organization under the Background of Rural Revitalization显示文摘The development of farmer organization will play an important role in rural revitalization. Basic pathways of farmer organization development are excavating common interest,playing the role of farmer elite,cultivating modern farmers and increasing government support. But due to the influences of rural culture tradition and current management system,there exists certain difficulty to meet these conditions to different extents,which decides that benign development of farmer organization will be a long persistence process. | Junpu ZHANG | 2018 | Asian Agricultural Research2018，10，5： | 1 |
| 8 | Effects of oxygen potential and flux composition on dephosphorization and rephosphorization of molten steel显示文摘The dephosphorization experiments of low phosphorus containing steel by CaO-based and BaO-based fluxes were carried out. The effects of the oxygen potential in molten steel and the BaO content in the slag on dephosphorization and rephosphorization of molten steel were analyzed. The results showed that the dephosphorization ratio of more than 50% and the ultra-low phosphorus content of less than 0.005% in steel were obtained by the three kinds of dephosphorization fluxes as the oxygen potential of molten steel higher than 400×10-6. Rephosphorization of molten steel was serious as the oxygen content of molten steel lower than 10×10-6. BaO-based fluxes can improve the dephosphorization effect and reduce the phosphorus pick-up effectively under the condition of weak deoxidization of molten steel (the oxygen potential is about 100×10-6), but can not prevent rephosphorization under the condi- tion of deep deoxidization of molten steel (the oxygen potential less than 10×10-6). | Zhihong Tian Junpu Jiang Kaike Cai XinhuaWang Lixin Zhu Xiaodong Yin Hongzhi Shi | 2005 | Journal of University of Science and Technology Beijing2005，12，5： | 1 |
| 9 | Intelligent Control and Automation显示文摘 | Zheng Quan Wang Junpu Wu Xiuqing | 2000 | Proceedings of the 3rd World Congress2000，，1： | 1 |
| 10 | Measurement of Raman scattering gain coefficient in large-aperture DKDP crystals irradiated by 351 nm pulses显示文摘Transverse stimulated Raman scattering (TSRS) gain coefficient in a large aperture 65% deu terated potassium dihydrogen phosphate (DKDP) is measured at 351 nm. The measurement involves the use of an optical fiber sensor system to detect Raman scattering light in the DKDP crystal. A Raman scattering gain coefficient of 0. 109 cm/GW is obtained and will be used to set upper limit of the DKDP crystals in our laser fa cility to avoid the TSRS induced energy loss and laser damage. The effect of bulk damage on growth behavior of TSRS is also examined and it is found that bulk damage has little impact on the TSRS growth. Thus the influ ence of bulk damage on the measurement of TSRS gain coefficient can be ignored. | Han Wei Xiang Yong Wang Fang Zhou Lidan Feng Bin Li FUCluan Zhao Junpu Zheng Kuixing Zhu Qihua Wei Xiaofeng Zheng Wanguo Gong Mali | 2016 | 强激光与粒子束2016，28，2： | 0 |
| 11 | Preparation of Peanut Shell Cellulose Double-Network Hydrogel and Its Adsorption Capacity for Methylene Blue显示文摘To achieve optimal recovery and value-added utilisation of cellulose in peanut shells,the cellulose in peanut shells was first extracted using the sodium hydroxide-sodium chlorite method.Then,cellulose hydrogel was prepared by graft copolymerisation using N,N’-methylenebisacrylamide as the cross-linking agent,sodium persulfate as the initiator,and acrylic acid as the monomer.Orthogonal optimisation experiments were designed to obtain optimal process parameters for hydrogel preparation with the cellulose dosage of 0.40 g,initiator dosage of 0.20 g,polymerisation temperature of 70°C,cross-linking agent of 0.25 g,and monomer dosage of 3.0 mL.The effect of initiator dosage on hydrogel synthesis was the most significant,followed by monomer dosage and reaction temperature.Characterisation using X-ray diffraction analysis and scanning electron microscopy revealed that the hydrogel was amorphous and exhibited a distinct three-dimensional double network structure.Hydrogel swelling kinetic analysis showed that the hydrogel swelling process was divided into three stages,and fitted the Schott secondary swelling kinetic model.The prepared hydrogel had a good adsorption effect on methylene blue;the adsorption of methylene blue by the hydrogel was 1.259 mg/g at 25°C when the initial concentration of methylene blue was 5 mg/L.The adsorption kinetics of the hydrogel fit the pseudo-first-order kinetic model,pseudo-secondorder kinetic model,Eovich model and particle diffusion model.The best fitting effect was obtained with the pseudo-second-order kinetic model.The adsorption isotherm analysis of methylene blue on hydrogel showed that the adsorption process was consistent with Langmuir and Freundlich models.The correlation coefficient of the Freundlich isotherm model was higher,indicating that the adsorption of methylene blue on hydrogel was mainly chemisorption. | Yalin Li Lei Liu Wenbao Huang Junpu Xie Zhaoxia Song Shuna Guo Enci Wang | 2023 | Journal of Renewable Materials2023，11，7： | 0 |
| 12 | Expression of miR-224, miR-145, and their putative target ADAM17 in hepatocellular carcinoma显示文摘 | Yuwu Liu Chang Wu Ying Wang Sailan Wen Junpu Wang Zhihong Chen Qiongqiong He Deyun Feng | 2014 | Acta Biochimica et Biophysica Sinica2014，46，8： | 0 |
| 13 | Dilemma and Path for Rural Mutual Aid Elderly Care Model in Underdeveloped Areas——A Case Study of Dazhou City in Sichuan Province显示文摘Rural mutual aid elderly care,as an emerging elderly care model,has become an exploration and attempt to rebuild rural communities in the process of rural social transformation.At present,in the vast underdeveloped rural areas,the rural mutual aid elderly care model is faced with such problems as imperfect policies and regulations,insufficient funds,single service items,lack of professional services,and limited functions of civil organizations.It is necessary to strengthen the formulation and improvement of laws and regulations,and to ensure the stable source of funds,enhance the level of specialization,and give full play to the functions of social organizations in the rural mutual aid elderly care model,so as to promote the sustainable development of the rural mutual aid elderly care model. | Junpu ZHANG | 2019 | Asian Agricultural Research2019，11，1： | 0 |
| 14 | The Predicament of Rural Development under the Strategy of Rural Revitalization显示文摘Solving rural poverty is the most urgent problem to be solved in the current rural revitalization strategy.The'alienation'of farmer organizations makes it difficult to give full play to the function of farmer organizations.The institutionalized obstacle of urban-rural dual division restricts the urban integration of migrant workers.There is an institutional conflict between the construction of new countryside and rural urbanization.It is the best way for farmers to find a suitable model for local development according to local conditions,but the exploration and practice of rural development model will be a complex and tortuous process. | Junpu ZHANG | 2019 | Asian Agricultural Research2019，11，11： | 0 |
| 15 | Strength enhancement of nanocrystalline tungsten under high pressure显示文摘Three tungsten powder samples—one coarse grained(c-W;grain size:1μm–3μm)and two nanocrystalline(n-W;average grain sizes:10nm and 50 nm)—are investigated under nonhydrostatic compression in a diamond anvil cell in separate experiments,and their in situ X-ray diffraction patterns are recorded.The maximum microscopic deviatoric stress in each tungsten sample,a measure of the yield strength,is determined by analyzing the diffraction line width.Over the entire pressure range,the strength of tungsten increases noticeably as the grain size is decreased from 1μm–3μmto 10 nm.The results show that the yield strength of tungsten with an average crystal size of 10nmis around 3.5 times that of the sample with a grain size of 1μm–3μm. | Jing Yang Wen Deng Qiang Li Xin Li Akun Liang Yuzhu Su Shixue Guan Junpu Wang Duanwei He | 2020 | Matter and Radiation at Extremes2020，5，5： | 0 |
| 16 | Microbiota-mediated shaping of mouse spleen structure and immune function characterized by scRNA-seq and Stereo-seq显示文摘Gut microbes exhibit complex interactions with their hosts and shape an organism's immune system throughout its lifespan.As the largest secondary lymphoid organ,the spleen has a wide range of immunological functions.To explore the role of microbiota in regulating and shaping the spleen,we employ scRNA-seq and Stereo-seq technologies based on germ-free(GF)mice to detect differences in tissue size,anatomical structure,cell types,functions,and spatial molecular characteristics.We identify 18 cell types,9 subtypes of T cells,and 7 subtypes of B cells.Gene differential expression analysis reveals that the absence of microorganisms results in alterations in erythropoiesis within the red pulp region and congenital immune deficiency in the white pulp region.Stereo-seq results demonstrate a clear hierarchy of immune cells in the spleen,including marginal zone(MZ)macrophages,MZ B cells,follicular B cells and T cells,distributed in a well-defined pattern from outside to inside.However,this hierarchical structure is disturbed in GF mice.Ccr7 and Cxcl13 chemokines are specifically expressed in the spatial locations of T cells and B cells,respectively.We speculate that the microbiota may mediate the structural composition or partitioning of spleen immune cells by modulating the expression levels of chemokines. | Yin Zhang Juan Shen Wei Cheng Bhaskar Roy Ruizhen Zhao Tailiang Chai Yifei Sheng Zhao Zhang Xueting Chen Weiming Liang Weining Hu Qijun Liao Shanshan Pan Wen Zhuang Yangrui Zhang Rouxi Chen Junpu Mei Hong Wei Xiaodong Fang | 2023 | Journal of Genetics and Genomics2023，50，9： | 0 |
| 17 | Recent Advances and Emerging Applications of the Singular Boundary Method for Large-Scale and High-Frequency Computational Acoustics显示文摘With the rapid development of computer technology,numerical simulation has become the third scientific research tool besides theoretical analysis and experi-mental research.As the core of numerical simulation,constructing efficient,accurate and stable numerical methods to simulate complex scientific and engineering prob-lems has become a key issue in computational mechanics.The article outlines the ap-plication of singular boundary method to the large-scale and high-frequency acoustic problems.In practical application,the key issue is to construct efficient and accurate numerical methodology to calculate the large-scale and high-frequency soundfield.This article focuses on the following two research areas.They are how to discretize partial differential equations into more appropriate linear equations,and how to solve linear equations more efficiently.The bottle neck problems encountered in the compu-tational acoustics are used as the technical routes,i.e.,efficient solution of dense linear system composed of ill-conditioned matrix and stable simulation of wave propagation at low sampling frequencies.The article reviews recent advances in emerging appli-cations of the singular boundary method for computational acoustics.This collection can provide a reference for simulating other more complex wave propagation. | Junpu Li Zhuojia Fu Yan Gu Qing-Hua Qin | 2022 | Advances in Applied Mathematics and Mechanics2022，14，2： | 0 |
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