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| 1 | Vertical distribution of aerosol optical properties based on aircraft measurements over the Loess Plateau in China显示文摘Vertical distributions of aerosol optical properties based on aircraft measurements over the Loess Plateau were measured for the first time during a summertime aircraft campaign, 2013 in Shanxi, China. Data from four flights were analyzed. The vertical distributions of aerosol optical properties including aerosol scattering coefficients(σsc), absorption coefficients(σab),Angstr?m exponent(α), single scattering albedo(ω), backscattering ratio(βsc), aerosol mass scattering proficiency(Q sc) and aerosol surface scattering proficiency(Q sc′) were obtained. The mean statistical values of σsc were 77.45 Mm-1(at 450 nm), 50.72 Mm-1(at 550 nm), and32.02 Mm-1(at 700 nm). The mean value of σab was 7.62 Mm-1(at 550 nm). The mean values ofα, βsc and ω were 1.93, 0.15, and 0.91, respectively. Aerosol concentration decreased with altitude. Most effective diameters(ED) of aerosols were less than 0.8 μm. The vertical profiles of σsc,, α, βsc, Q sc and Q sc′ showed that the aerosol scattering properties at lower levels contributed the most to the total aerosol radiative forcing. Both α and βsc had relatively large values, suggesting that most aerosols in the observational region were small particles. The mean values of σsc, α, βsc, Q sc, Q sc′, σab and ω at different height ranges showed that most of the parameters decreased with altitude. The forty-eight hour backward trajectories of air masses during the observation days indicated that the majority of aerosols in the lower level contributed the most to the total aerosol loading, and most of these particles originated from local or regional pollution emissions. | Junxia Li Xingang Liu Liang Yuan Yan Yin Zhanqing Li Peiren Li Gang Ren Lijun Jin Runjun Li Zipeng Dong Yiyu Li Junmei Yang | 2015 | Journal of Environmental Sciences2015，27，8： | 6 |
| 2 | Auranofin mitigates systemic iron overload and induces ferroptosis via distinct mechanisms显示文摘Iron homeostasis is essential for health;moreover,hepcidin-deficiency results in iron overload in both hereditary hemochromatosis and iron-loading anemia.Here,we identified iron modulators by functionally screening hepcidin agonists using a library of 640 FDA-approved drugs in human hepatic Huh7 cells.We validated the results in C57BL/6J mice and a mouse model of hemochromatosis(Hfe^(−/−)mice).Our screen revealed that the anti-rheumatoid arthritis drug auranofin(AUR)potently upregulates hepcidin expression.Interestingly,we found that canonical signaling pathways that regulate iron,including the Bmp/Smad and IL-6/Jak2/Stat3 pathways,play indispensable roles in mediating AUR’s effects.In addition,AUR induces IL-6 via the NF-κB pathway.In C57BL/6J mice,acute treatment with 5 mg/kg AUR activated hepatic IL-6/hepcidin signaling and decreased serum iron and transferrin saturation.Whereas chronically treating male Hfe^(−/−)mice with 5 mg/kg AUR activated hepatic IL-6/hepcidin signaling,decreasing systemic iron overload,but less effective in females.Further analyses revealed that estrogen reduced the ability of AUR to induce IL-6/hepcidin signaling in Huh7 cells,providing a mechanistic explanation for ineffectiveness of AUR in female Hfe^(−/−)mice.Notably,high-dose AUR(25 mg/kg)induces ferroptosis and causes lipid peroxidation through inhibition of thioredoxin reductase(TXNRD)activity.We demonstrate the ferroptosis inhibitor ferrostatin significantly protects liver toxicity induced by highdose AUR without comprising its beneficial effect on iron metabolism.In conclusion,our findings provide compelling evidence that TXNRD is a key regulator of ferroptosis,and AUR is a novel activator of hepcidin and ferroptosis via distinct mechanisms,suggesting a promising approach for treating hemochromatosis and hepcidin-deficiency related disorders. | Lei Yang Hao Wang Xiang Yang Qian Wu Peng An Xi Jin Weiwei Liu Xin Huang Yuzhu Li Shiyu Yan Shuying Shen Tingbo Liang Junxia Min Fudi Wang | 2020 | Signal Transduction and Targeted Therapy2020，5，1： | 5 |
| 3 | An HDR Imaging Method With DTDI Technology for Push-Broom Cameras显示文摘通常,高动态范围(HDR ) 成像基于拿二或有不同暴露的一样的景色的更多的图画。由于在照相机和景色之间的一个高速度的相对运动,然而,要用于推扫帚遥感照相机,为这种技术是难的。为在推扫帚遥感应用的 HDR 成像的缘故,现在的纸建议没有冗余的图象传感器或光部件,能产生 HDR 图象的一个创新方法。明确地,这份报纸与数字领域 time-delay-integration (DTDI ) 采用一个区域数组互补金属氧化物半导体(互补金属氧化物半导体) 为成像的技术而不是多于一个排图象传感器采用,从而与不同暴露拍摄超过一张照片。然后由与一个简单算法熔化二幅原来的图象的一幅新 HDR 图象能被完成。由进行实验,图象的动态范围(医生) 由 26.02 dB 增加。建议方法被证明有效并且在在照相机和场面之间有一个相对运动的另外的成像应用有潜力。 | Wu SUN Chengshan HAN Xucheng XUE Hengyi LV Junxia SHI Changhong HU Xiangzhi LI Yao FU Xiaonan JIANG Liang HUANG Hongyin HAN | 2018 | Photonic Sensors2018，8，1： | 4 |
| 4 | Prediction of sorghum miRNAs and their targets with computational methods显示文摘microRNAs 是 21-nt 的一个班在 post-transcriptional 起关键作用的长、非编码、最新识别的 RNA 基因规定。他们的目标涉及各种各样的生物过程,包括开发,新陈代谢,和压力反应。尽管很多 miRNAs 在许多种类被报导了,在蜀黍的 miRNAs 的报告是有限的。基于 genomic 调查顺序(GSS ) 和 microRNA (miRNA ) 使用相同搜索第二等的结构, 17 新 miRNAs 的一个总数在这个工作被识别。他们被发现在 11 个 miRNA 家庭之中不均匀的分布式。一些 miRNA 基因在多重地点并且在超过一 genomic 上下文被发现。大多数 miRNAs 在一样的王国以内被保存,但是我们在蜀黍发现 sbi-miR127 和 sbi-miR466 与 H 显示出保存。现代人并且 M。musculus 分别地。经由联机软件 miRU 的那些 17 新 miRNAs 的分析证明他们可能调整 64 目标基因,其大多数涉及 RNA 处理,新陈代谢,房间周期,蛋白质降级,压力反应和交通。11 个 miRNA 家庭中的至少 7 个指向在新陈代谢和压力反应是必要的蛋白质,包括 NADPH 细胞色素 P450 reductase, nucleoside diphosphate kinase 和 superoxide dismutase,建议 miRNAs 起在生物过程的一个必要作用。 | DU JiangFeng WU YongJun FANG XiaoFeng CAO JunXia ZHAO Liang TAO ShiHeng | 2010 | Chinese Science Bulletin2010，55，13： | 2 |
| 5 | A reactive molecular dynamics study of n?heptane pyrolysis at high temperature显示文摘 | Ding Junxia Zhang Liang Zhang Yan | 2013 | The Journal of Physical Chemistry2013，117，16： | 1 |
| 6 | Astrocyte dysfunction in Parkinson's Check for updates disease:from the perspectives of transmittedα-synuclein and genetic modulation显示文摘Parkinson's disease(PD)is a common neurodegenerative disorder that primarily affects the elderly.While the etiology of PD is likely multifactorial with the involvement of genetic,environmental,aging and other factors,α-synuclein(α-syn)pathology is a pivotal mechanism underlying the development of PD.In recent years,astrocytes have attracted considerable attention in the field.Although astrocytes perform a variety of physiological functions in the brain,they are pivotal mediators ofα-syn toxicity since they internalizeα-syn released from damaged neurons,and this triggers an inflammatory response,protein degradation dysfunction,mitochondrial dysfunction and endoplasmic reticulum stress.Astrocytes are indispensable coordinators in the background of several genetic mutations,including PARK7,GBA1,LRRK2,ATP13A2,PINK1,PRKN and PLA2G6.As the most abundant glial cells in the brain,functional astrocytes can be replenished and even converted to functional neurons.In this review,we discuss astrocyte dysfunction in PD with an emphasis onα-syn toxicity and genetic modulation and conclude that astrocyte replenishment is a valuable therapeutic approach in PD. | Changjing Wang Tongtong Yang Meiyu Liang Junxia Xie Ning Song | 2021 | Translational Neurodegeneration2021，10，4： | 1 |
| 7 | Monitoring the morphology evolution of LiNi_(0.8)Mn_(0.1)Co_(0.1)O_(2)during high-temperature solid state synthesis via in situ SEM显示文摘The particle morphology determined by the sintering process is the director factor affecting the electrochemical performance of Ni-rich NMC cathode materials.To prepare the ideal NMC particles,it is of great significance to understand the morphological changes during sintering process.In this work,the morphology evolution of LiNi_(0.8)Mn_(0.1)Co_(0.1)O_(2)(NMC811)synthesis at temperature ranging from 300–1080℃were observed by in situ SEM.The uniform mixture of spherical Ni_(0.8)Mn_(0.1)Co_(0.1)(OH)_(2)precursor and lithium sources(LiOH)was employed by high temperature solid-state process inside the SEM,which enables us to observe morphology changes in real time.The results show that synthetic reaction of LiNi_(0.8)Mn_(0.1)Co_(0.1)O_(2)usually includes three processes:the raw materials’dehydration,oxidation,and combination,accompanied by a significant reduction in particle size,which is important reference to control the synthesis temperature.As heating temperature rise,the morphology of mixture also changed from flake to brick-shaped.However,Ni nanoparticle formation is apparent at higher temperature~1000℃,suggesting a structural transformation from a layered to a rock-salt-like structure.Combining the in-situ observed changes in size and morphology,and with the premise of ensuring the morphology change from flakes to bricks,reducing the sintering temperature as much as possible to prevent excessive reduction in particle size and layered to a rock-salt structure transformation is recommended for prepare ideal NMC particles. | Liang Tang Xiaopeng Cheng Rui Wu Tianci Cao Junxia Lu Yuefei Zhang Ze Zhang | 2022 | Journal of Energy Chemistry2022，31，3： | 1 |
| 8 | Novel Fluorescent Chemosensor for Detection of F- Anions Based on a Single Functionalized Pillar[5]arene Iron(Ⅲ) Complex显示文摘 | Youming Zhang Junxia Su Qiao Li Wenting Li Guoyan Liang Hui Li Haixia Ma Qi Lin Hong Yao Taibao Wei | 2016 | Chinese Journal of Chemistry2016，34，12： | 0 |
| 9 | A 2D Staggered Multi-Material ALE Code Using MOF Interface Reconstruction显示文摘Hydrocodes are necessary numerical tools in the fields of implosion and high-velocity impact,which often involve large deformations with changing-topology interfaces.It is very difficult for Lagrangian or Simplified Arbitrary Lagrangian-Eulerian(SALE)codes to tackle these kinds of large-deformation problems,so a stag-gered Multi-Material ALE(MMALE)code is developed in this paper,which is the explicit time-marching Lagrange plus remap type.We use the Moment Of Fluid(MOF)method to reconstruct the interfaces of multi-material cells and present an adaptive bisection method to search for the global minimum value of the nonlinear objective function.To keep the Lagrangian computations as long as possible,we develop a ro-bust rezoning method named as Combined Rezoning Method(CRM)to generate the convex,smooth grids for the large-deformation domain.Regarding the staggered remap phase,we use two methods to remap the variables of Lagrangian mesh to the rezoned one.One is the first-order intersection-based remapping method that doesn’t limit the distances between the rezoned and Lagrangian meshes,so it can be used in the applications of wide scope.The other one is the conservative second-order flux-based remapping method developed by Kucharika and Shashkov[22]that requires the rezoned element to locate in its adjacent old elements.Numerical results of triple point problem show that the result of first-order remapping method using ALE computations is gradually convergent to that of second-order remapping method using Eulerian computations with the decrease of rezoning,thereby telling us that MMALE computations should be performed as few as possible to reduce the errors of the interface reconstruction and the remapping.Numerical results provide a clear evidence of the robustness and the accuracy of this MMALE scheme,and that our MMALE code is powerful for the large-deformation problems. | Yibing Chen Junxia Cheng Liang Pan Haihua Yang Heng Yong Xin Yu | 2021 | Numerical Mathematics(Theory,Methods and Applications)2021，14，1： | 0 |
| 10 | Novel Ag-bridged dual Z-scheme g-C_(3)N_(4)/BiOI/AgI plasmonic heterojunction: Exceptional photocatalytic activity towards tetracycline and the mechanism insight显示文摘Rational design and synthesis of highly efficient and robust photocatalysts with positive exciton splitting and interfacial charge transfer for environmental applications is critical.Herein,aiming at overcoming the common shortcomings of traditional photocatalysts such as weak photoresponsivity,rapid combination of photo-generated carriers and unstable structure,a novel Ag-bridged dual Z-scheme g-C_(3)N_(4)/BiOI/AgI plasmonic heterojunction was successfully synthesized using a facile method.Results showed that Ag-AgI nanoparticles and three-dimensional(3D)BiOI microspheres were decorated highly uniformly on the 3D porous g-C_(3)N_(4) nanosheet,resulting in a higher specific surface area and abundant active sites.The optimized 3D porous dual Z-scheme g-C_(3)N_(4)/BiOI/Ag-AgI manifested exceptional photocatalytic degradation efficiency of tetracycline(TC)in water with approximately 91.8%degradation efficiency within 165 min,outperforming majority of the reported g-C_(3)N_(4)-based photocatalysts.Moreover,g-C_(3)N_(4)/BiOI/Ag-AgI exhibited good stability in terms of activity and structure.In-depth radical scavenging and electron paramagnetic resonance(EPR)analyses confirmed the relative contributions of various scavengers.Mechanism analysis indicated that the improved photocatalytic performance and stability were ascribed to the highly ordered 3D porous framework,fast electron transfer of dual Z-scheme heterojunction,desirable photocatalytic performance of BiOI/AgI and synergistic effect of Ag plasmas.Therefore,the 3D porous Z-scheme g-C_(3)N_(4)/BiOI/Ag-AgI heterojunction had a good prospect for applications in water remediation.The current work provides new insight and useful guidance for designing novel structural photocatalysts for environment-related applications. | Wenxia Wang Zhen Li Kailin Wu Guodong Dai Qingping Chen Lihua Zhou Junxia Zheng Liang Ma Guiying Li Wanjun Wang Taicheng An | 2023 | Journal of Environmental Sciences2023，，9： | 0 |
| 11 | Two-stage reproduction derived from cells of thallus could directly contribute to seeds for green tidal algal Enteromorpha(Ulva) prolifera/clathrata bloom,with disclosure of their ephemeral trait显示文摘Green tidal algal Enteromorpha species complete their life cycles by the isomorphic alternation of generations.The provenance of green tide caused by them in the western Yellow Sea has been disputed. The cell reproduction derived from adult thallus was observed on E. clathrata collected from Shantou City, Guangdong Province in this study. Subsequently, it further found that E. proliferia collected from Qingdao City, Shandong Province and Qinhuangdao City, Hebei Province, produced reproductive cells by somatic cells of its early infantile thallus or branch. The latter is functionally similar to that the seedlings of red alga Porphyra yezoensis produce the monospores, and could exquisitely explain the ephemeral or opportunistic trait and environmental adaptation ability of Enteromorpha species. Changes in growth conditions may induce the two types of cell reproduction.They contribute to the bloom, and can effectively reveal the seasonally occurring large-scale and on-year and offyear phenomenon. The latter may have played a decisive role in its formation. This paper analyses the legal status of the species name, the type of generation during bloom, ephemeral traits, the role of microscopic propagule, the area of origin, on-year and off-year phenomenon, early warning and prevention and control of the species, and so on. On this basis, further study on the influence of environmental factors on cell reproduction of early infantile thalli or branches will achieve a positive effect for early warning and prevention and control of the green tidal algal bloom. | Bingxin Huang Lanping Ding Yao Zhang Youxuan Guo Junxia Liang Yanqi Xie Yue Chu | 2023 | Acta Oceanologica Sinica2023，42，9： | 0 |
| 12 | LEAF项目建设状态报告显示文摘LEAF or the Low Energy heavy ion Accelerator Facility is a multidiscipline heavy ion research platform under construction at IMP.It is a 5 year National Major Instruments Research Program supported by National Science Foundation of China(NSFC)started in 2015.Oriented to the frontier research in Material Sciences,Astrophysics,Atomic Physics and Highly Charged Ion Physics,LEAF has been designed and constructed with the state of the art technologies for low energy heavy ion acceleration.This facility features a 45 GHz ECR ion source FECR,a heavy ion CW 4-vane radio frequency quadruple accelerator LRFQ,300 kV HV platform,LEBT,MEBT and several dedicated experimental terminals. | Sun Liangting Yang Yao Lu Liang Guo Yuhui Liu Xiaojun Jing Long Li Libin Sun Liepeng Gao Zheng Ma Hongyi Jin Xiaofeng Zhai Yuhan Xu Xianbo Shi Longbo Xing Chaochao Liu Yuting Zhu Tieming Hu Qiang Zhang Peng Zhang Xuezhen Fang Xing Jia Huan Zhang Bin Liu Chaodong Ma Yingming Zhao Bo Wu Beimin Zhu Li Li Jiaqing Lu Wang Guo Junwei Li Chenxing Wang Zhijun Dou Weiping Wu Junxia Zhang Zimin Yao Qinggao Wu Wei Zhou Zhongzu Zhang Junhui Ma Lizhen He Yuan Zhao Hongwei | 2018 | IMP & HIRFL Annual Report2018，，1： | 0 |
| 13 | LEAF项目建设状态报告显示文摘LEAF or the Low Energy heavy ion Accelerator Facility is a multidiscipline heavy ion research platform constructing at IMP.It is a 5-year National Major Instruments Research Program supported by National Science Foundation of China(NSFC)started in 2015.Oriented to the frontier research in material sciences,astrophysics,atomic physics and highly charged ion physics,LEAF has been designed and constructed with the state-of-the-art technologies for low energy heavy ion acceleration.This facility features a 45 GHz ECR ion source FECR,a heavy ion CW 4-vane radio frequency quadruple accelerator LRFQ,300 kV HV platform,LEBT,MEBT and several dedicated experimental terminals.The layout of LEAF is given in Fig.1. | Sun Liangting Lu Liang Jia Huan Yang Yao Zhang Bin Guo Yuhui Gao Zheng Ma Hongyi Jin Xiaofeng Zhu Tieming Hu Qiang Zhang Peng Zhang Xuezhen Fang Xing Jing Long Liu Chaodong Ma Yingming Zhao Bo Wu Beimin Liu Xiaojun Li Jiaqing Lu Wang Guo Junwei Yang Long Li Libin Sun Liepeng Shi Longbo Li Chenxing Ma Wei Wang Zhijun Dou Weiping Wu Junxia Zhang Zimin Yao Qinggao Wu Wei Zhou Zhongzu Zhang Junhui Ma Lizhen He Yuan Zhao Hongwei | 2017 | IMP & HIRFL Annual Report2017，，1： | 0 |
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