| 3 | Drones,virtual reality,and modeling:communicating catastrophic dam failure显示文摘Dam failures occur worldwide and can be economically and ecologically devastating.Communicating the scale of these risks to the general public and decision-makers is imperative.Two-dimensional(2D)dam failure hydraulic models inform owners and floodplain managers of flood regimes but have limitations when shared with non-specialists.This study addresses these limitations by constructing a 3D Virtual Reality(VR)environment to display the 1976 Teton Dam disaster case study using a pipeline composed of(1)2D hydraulic model data(extrapolated into 3D),(2)a 3D reconstructed dam,and(3)a terrain model processed from UAS(Uncrewed Airborne System)imagery using Structure from Motion photogrammetry.This study validates the VR environment pipeline on the Oculus Quest 2 VR Headset with the criteria:immersion fidelity,movement,immersive soundscape,and agreement with historical observations and terrain.Through this VR environment,we develop an effective method to share historical events and,with future work,improve hazard awareness;applications of this method could improve citizen engagement with Early Warning Systems.This paper establishes a pipeline to produce a visualization tool for merging UAS imagery,Virtual Reality,digital scene creation,and sophisticated 2D hydraulic models to communicate catastrophic flooding events from natural or human-made levees or dams. | H.R.Spero I.Vazquez-Lopez K.Miller R.Joshaghani S.Cutchin J.Enterkine | 2022 | International Journal of Digital Earth2022，15，1： | 1 |
| 4 | Functional recovery after peripheral nerve injury via sustained growth factor delivery from mineral-coated microparticles显示文摘The gold standard for treating peripheral nerve injuries that have large nerve gaps where the nerves cannot be directly sutured back together because it creates tension on the nerve,is to incorporate an autologous nerve graft.However,even with the incorporation of a nerve graft,generally patients only regain a small portion of function in limbs affected by the injury.Although,there has been some promising results using growth factors to induce more axon growth through the nerve graft,many of these previous therapies are limited in their ability to release growth factors in a sustained manner and tailor them to a desired time frame.The ideal drug delivery platform would deliver growth factors at therapeutic levels for enough time to grow axons the entire length of the nerve graft.We hypothesized that mineral coated microparticles(MCMs)would bind,stabilize and release biologically active glial cell-derived neurotrophic factor(GDNF)and nerve growth factor(NGF)in a sustained manner.Therefore,the objective of this study was to test the ability of MCMs releasing growth factors at the distal end of a 10 mm sciatic nerve graft,to induce axon growth through the nerve graft and restore hind limb function.After sciatic nerve grafting in Lewis rats,the hind limb function was tested weekly by measuring the angle of the ankle at toe lift-off while walking down a track.Twelve weeks after grafting,the grafts were harvested and myelinated axons were analyzed proximal to the graft,in the center of the graft,and distal to the graft.Under physiological conditions in vitro,the MCMs delivered a burst release of NGF and GDNF for 3 days followed by a sustained release for at least 22 days.In vivo,MCMs releasing NGF and GDNF at the distal end of sciatic nerve grafts resulted in significantly more myelinated axons extending distal to the graft when compared to rats that received nerve grafts without growth factor treatment.The rats with nerve grafts incorporated with MCMs releasing NGF and GDNF also showed significant improvement in hind limb function starting at 7 weeks postoperatively and continuing through 12 weeks postoperatively when compared to rats that received nerve grafts without growth factor treatment.In conclusion,MCMs released biologically active NGF and GDNF in a sustained manner,which significantly enhanced axon growth resulting in a significant improvement of hind limb function in rats.The animal experiments were approved by University of Wisconsin-Madison Animal Care and Use Committee(ACUC,protocol#M5958)on January 3,2018. | Daniel J.Hellenbrand Clayton L.Haldeman Jae-Sung Lee Angela G.Gableman Elena K.Dai Stephen D.Ortmann Jerrod CGotchy Kierra K.Miller Adrianna M.Doucas Nicole C.Nowak William L.Murphy Amgad S.Hanna | 2021 | Neural Regeneration Research2021，16，5： | 0 |
| 6 | 通过分析羽状流的分布来评价大陆坡上甲烷水合物的分解显示文摘卡斯卡迪亚古陆边缘沉积层中含有丰富的碳库,其来源一方面是物质从陆地的不断输入,另一方面是来自海水表层生产力。该碳资源中有一部分是以固态的天然气水合物形式存在于沉积层的孔隙中,之前有研究表明在温哥华岛和卡斯卡迪亚古陆边缘的俄勒冈州区域都有大量甲烷资源的存在。卡斯卡迪亚古陆边缘多道地震反射剖面表明该区域沉积层中普遍存在似海底反射(BSR),这意味着天然气水合物从3000m水深的形变前缘到500m水深的天然气水合物稳定区上临界位置都有分布。在本研究中我们汇总了卡斯卡迪亚古陆边缘经过一系列由不同的研究目的而进行的勘探确定存在甲烷羽状流的点位,同时也包含一些商业渔民主动提供的点位信息。高密度羽状流这一反常现象的出现和大陆架(小于180m)结构以及甲烷水合物稳定区域(MHSD)上限深度有关,甲烷水合物稳定区在东北太平洋区域一般为500m左右。在卡斯卡迪亚古陆坡观测到的这一异常现象可能是由于中层深度海水变暖引起的,这表明现代气候变暖已经开始使得对气候变化非常敏感的卡斯卡迪亚古陆边缘地带沉积层中的水合物开始出现失稳状态。针对北美大西洋斜坡相似的羽状流图像的重新分析表明在很多纬度范围内观测到的羽状流深度和MHSD之间联系不大。 | H.Paul Johnson Una K.Miller Marie S.Salmi 龚焕燊 | 2015 | 海洋地质2015，0，4： | 0 |
| 7 | 大学生多系统人际关系特征之中美比较显示文摘目的根据Leary发展的人际圆环理论研究大学生与父母、与同学、与老师的人际关系特征,在横轴为积极情感对消极情感,纵轴为分化对联结的框架中予以分类比较。方法方便取样获得中国被试156名和美国被试100名,让其对自己大学期间的3类人际关系进行十分钟的纸笔词语联想。结果两国大学生人际特征词语可按照人际圆环理论纳入4个象限,词频统计发现在4个象限的分布上有统计学意义的显著差异。与美国大学生相比,中国大学生的人际关系特征为较多的消极情感体验,与父母关系相对友好亲密,较少独立分化;与同学关系有较多的消极情感的分离和联结;与教师关系则相对更多疏离回避。结论两国大学生人际关系特征存在共性和差异,与文化背景、教育现实有关。 | 姚玉红 赵旭东 John K.Miller | 2010 | 上海精神医学2010，22，B12： | 0 |
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