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| 1 | 2016版WHO淋巴肿瘤分类修订解读显示文摘自2008年第4版世界卫生组织(WHO)造血与淋巴组织肿瘤分类(以下称2008版)发布以来,淋巴组织肿瘤的临床与基础研究取得巨大进展,有些类型的淋巴瘤需要重新定义,同时也报道一些新的亚型。 | 易树华 邹德慧 Ken He Young 邱录贵 | 2016 | 中华医学杂志2016，96，42： | 7 |
| 2 | Blastic Plasmacytoid Dendritic Cell Neoplasm:Progress in Cell Origin,Molecular Biology,Diagnostic Criteria and Therapeutic Approaches显示文摘Blastic plasmacytoid dendritic cell neoplasm(BPDCN)is a rare hematological malignancy characterized by recurrent skin nodules,an aggressive clinical course with rapid involvement of hematological organs,and a poor prognosis with poor overall survival.BPDCN is derived from plasmacytoid dendritic cells(pDCs)and its pathogenesis is unclear.The tumor cells show aberrant expression of CD4,CD56,interleukin-3 receptor alpha chain(CD 123),blood dendritic cell antigen 2(BDCA 2/CD303),blood dendritic cell antigen 4(BDCA4)and transcription factor(E protein)E2-2(TCF4).The best treatment drugs are based on experience by adopting those used for either leukemia or lymphoma.Relapse with drug resistance generally occurs quickly.Stem cell transplantation after the first complete remission is recommended and tagraxofusp is the first targeted therapy.In this review,we summarize the differentiation of BPDCN from its cell origin,its connection with normal pDCs,clinical characteristics,genetic mutations and advances in treatment of BPDCN.This review provides insights into the mechanisms of and new therapeutic approaches for BPDCN. | Wei CHENG Tian-tian YU Ai-ping TANG Ken HE YOUNG Li YUI | 2021 | Current Medical Science2021，41，3： | 4 |
| 3 | Infection complications in febrile chimeric antigen receptor(CAR)-T recipients during the peri-CAR-T cell treatment period examined using metagenomic next-generation sequencing(mNGS)显示文摘Dear Editor,Chimeric antigen receptor-engineered(CAR)-T cell therapy has achieved unprecedented efficacy on refractory/relapsed B-cell malignancies[1].Yet,CAR-T recipients are highly susceptible to infection due to the immunodeficiency caused by B-cell aplasia and the pretreatment with chemotherapy.However,due to the systematic use of empirical broad-spectrum antibiotics and immunosuppressors to control cytokine release syndrome(CRS)reaction,microbiological diagnosis of infection has remained challenging in CAR-T recipients. | Jiali Nie Li Yang Liang Huang Lili Gao Ken He Young Jehane Michael Le Grange Xingcheng Yang Jia Wei Min Xiao Jianfeng Zhou | 2022 | Cancer Communications2022，42，5： | 2 |
| 4 | Self- pierce riveting for sheet materials:state of the art 显示文摘 | He Xiaocong Ian Pearson Ken Young | 2008 | Journal of Materials Processing Technology2008，199，123： | 1 |
| 5 | Finite element analysis of self-pierce riveted joints 显示文摘 | He Xiaocong Ian Pearson Ken Young | 2007 | Key Engineering Materials2007，344，： | 1 |
| 6 | Three dimensional finite element analysis of transverse free vibration of self-pierce riveting beam 显示文摘 | He Xiaocong Ian Pearson Ken Young | 2007 | Key Engineering Materials2007，344，： | 1 |
| 7 | Self-pierce riveting for sheet materials:State of the art显示文摘 | He Xiaocong Pearson Ian Young Ken | | 0，，1： | 1 |
| 8 | Do ethnic and socio-economic inequalities in mortality vary by region in New Zealand? An application of hierarchical Bayesian modelling显示文摘 | Richardson Ken Blakely Tony Young Jim | 2009 | Social Science and Medicine2009，69，8： | 1 |
| 9 | Self - pierce riveting for sheet materials:state of the art显示文摘 | He Xiaoeong Ian Pearson Ken Young | 2008 | Journal of Materials Processing Technology2008，，1： | 1 |
| 10 | EML4-ALK Fusion Is Linked to Histological Characteristics in a Subset of Lung Cancers显示文摘 | Kentaro Inamura Kengo Takeuchi Yuki Togashi Kimie Nomura Hironori Ninomiya Michiyo Okui Yukitoshi Satoh Sakae Okumura Ken Nakagawa Manabu Soda Young Lim Choi Toshiro Niki Hiroyuki Mano Yuichi Ishikawa | 2008 | Journal of Thoracic Oncology2008，，1： | 1 |
| 11 | Self-pierce riveting for sheet materials: State of the art显示文摘 | Xiaocong He Ian Pearson Ken Young | 2008 | Journal of Materials Processing Technology2008，199，： | 1 |
| 12 | Self-pierce riveting for sheet materials: State of the art显示文摘 | Xiaocong He Ian Pearson Ken Young | 2007 | Journal of Materials Processing Tech2007，，1： | 1 |
| 13 | Self-pierce riveting for sheet materials: State of the art 显示文摘 | He Xiaocong Pearson Ian Young Ken | 2008 | J Mater Processing Technol2008，199，1： | 1 |
| 14 | An Actor-Net-work Theory Analysis of Policy Innovation for Smoke-FreePlaces: Understanding Change in Complex Systems显示文摘 | Young David Borland Ron Coghill Ken | 2010 | Ameri can Journal of Public Health2010，100，12： | 1 |
| 15 | Lenalidomide in combination with rituximab for patients with relapsed or refractory mantle-cell lymphoma: a phase 1/2 clinical trial显示文摘 | Michael Wang Luis Fayad Nicolaus Wagner-Bartak Liang Zhang Fredrick Hagemeister Sattva S Neelapu Felipe Samaniego Peter McLaughlin Michelle Fanale Anas Younes Fernando Cabanillas Nathan Fowler Kate J Newberry Luhong Sun Ken H Young Richard Champlin Larry | 2012 | Lancet Oncology2012，，： | 1 |
| 16 | Self-pierce rive ting for sheet materials: state of the art显示文摘 | He Xiaoeong Pearson Ian Young Ken | 2008 | Journal of Mate rials Processing Technology2008，199，： | 1 |
| 17 | Loss of CDKN 2A expression is a frequent event in primary invasive melanoma and correlates with sensitivity to the CDK 4/6 inhibitor PD 0332991 in melanoma cell lines显示文摘 | Richard J. Young Kelly Waldeck Claire Martin Jung H. Foo Donald P. Cameron Laura Kirby Hongdo Do Catherine Mitchell Carleen Cullinane Wendy Liu Stephen B. Fox Ken Dutton‐Regester Nicholas K. Hayward Nicholas Jene Alexander Dobrovic Richard B. Pearson Jame | 2014 | Pigment Cell Melanoma Res2014，，4： | 1 |
| 18 | Sap flow characteristics of neotropical mangroves in flooded and grained soils显示文摘 | KEN W K YOUNG P J JIM L | 2007 | Tree Physiology2007，27，： | 1 |
| 19 | Confronting the scientific obstacles to global control of tuberculosis显示文摘 | Young Douglas B Perkins Mark D Duncan Ken Barry Clifton E | 2008 | Journal of Clinical Investigation2008，，4： | 1 |
| 20 | Overexpressed BAG3 is a potential therapeutic target in chronic lymphocytic leukemia显示文摘 | Huayuan Zhu Wei Wu Yuan Fu Wenyi Shen Kourong Miao Min Hong Wei Xu Ken H. Young Peng Liu Jianyong Li | 2014 | Annals of Hematology2014，，3： | 1 |
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