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| 1 | 参与式渭南地震情景构建:中国地震风险对策的行动研究示范显示文摘中国政府层面自上而下的防震减灾管理卓有成效;但是,对于提升全社会的整体防震减灾能力而言,尚需推动基于此而又有民众与基层自下而上广泛参与的全社会治理模式。为发展这种模式积累经验,渭南市地震情景构建示范项目借助参与式行动研究范式,特别关注了中国防震减灾工作当前存在的以下2点广泛不足:一是社会民众与基层的自下而上办法薄弱,且与政府层面自上而下对策之间的相互衔接与促进不足;二是科学研究向实际减灾对策的转化不足,特别是针对自下而上办法的科学研究与应用转化不足。取得的主要进展有:1)基于广泛参与理念,通过'研究者'和'减灾实践者'、'相关者'、'当事人'2方面人员间的密切合作,共同诊断评估了渭南面临的主要地震灾害风险及隐患、共同提炼了针对性的减灾对策改进建议等,从而使情景构建所得的结果或认识更加可靠、所提对策建议更加符合当地实际需要;借助行动研究过程平台,尝试了风险评估、风险沟通和风险对策改进3大环节的无缝衔接与同步互动,促进了科学研究与实际应用的直接对接与就地转化。2)基于多尺度、多层面视角和同时为'政府'或'部门'与'基层'或'民众'两大类用户服务。在关注改进自上而下对策的同时,针对薄弱的自下而上办法,特别是就这两大对策途径间最广泛与最可持续的接口——宣传教育和家庭、学校、社区减灾,开展了大规模的专项调查分析,梳理了系列化的现今本底与改进方向。3)聚焦改善减灾宣教和促进风险沟通,编创了由'故事'引导的2版内容与形式均有显著差别的地震情景叙事读本:政府版和公众版,以期借助'故事'和艺术呈现'故事'带动人们更好地理解与应用情景构建结果和认识,借助'故事'演绎社会性灾害脆弱成分——'留守儿童家庭与贫困'之于灾害的强化与叠加效应,促进人们对地震灾害风险更加全面与深入的认识;在理性刻板科学中融入感性与人文艺术情怀,以引导共识与共鸣、改善减灾态度、培养减灾价值观,进而激发减灾行动和减灾参与意愿,特别是激励人们就相关问题进行长期思考和持续行动改善。以上3方面进展,从总体上实现了对中国防震减灾工作存在的前述2点广泛不足的有益研讨与部分弥补推动尝试。参与式渭南地震情景构建行动研究示范,对国内相关工作具有抛砖引玉的作用,也为国际同类工作积累了中国经验。 | 苏桂武 Janise Rodgers 田青 齐文华 Philip England Timothy Sim John Young 王东明 李志强 冯希杰 孙磊 陈鲲 Emily So Barry Parsons 赵金礼 石建梁 袁志祥 Yue Cao 周旗 魏本勇 David Milledge Alexander Densmore | 2020 | 地震地质2020,42,6: | 6 |
| 2 | Hepatobiliary scintigraphy for detecting biliary strictures after living donor liver transplantation显示文摘AIM:To investigate the diagnostic accuracy of hepatobiliary scintigraphy(HBS) in detecting biliary strictures in living donor liver transplantation(LDLT) patients.METHODS:We retrospectively reviewed 104 adult LDLT recipients of the right hepatic lobe with duct-toduct anastomosis,who underwent HBS and cholangiography.The HBS results were categorized as normal,parenchymal dysfunction,biliary obstruction,or bile leakage without re-interpretation.The presence of biliary strictures was determined by percutaneous cholangiography or endoscopic retrograde cholangiopancreatography(ERCP).RESULTS:In 89 patients with biliary strictures,HBS showed biliary obstruction in 50 and no obstruction in 39,for a sensitivity of 56.2%.Of 15 patients with no biliary strictures,HBS showed no obstruction in 11,for a specificity of 73.3%.The positive predictive value(PPV) was 92.6%(50/54) and the negative predictive value(NPV) was 22%(11/50).We also analyzed the diagnostic accuracy of the change in bile duct size.The sensitivity,NPV,specificity,and PPV were 65.2%,27.9%,80% and 95%,respectively.CONCLUSION:The absence of biliary obstruction on HBS is not reliable.Thus,when post-LDLT biliary strictures are suspected,early ERCP may be considered. | Yu Jin Kim Kyu Taek Lee Young Cheol Jo Kwang Hyuck Lee Jong Kyun Lee Jae-Won Joh Choon Hyuck David Kwon | 2011 | World Journal of Gastroenterology2011,17,21: | 6 |
| 3 | AME证据系列001--转化医学协会:脓毒症诊断和早期识别的临床实践指南显示文摘脓毒症是一种由感染引起的异质性疾病,感染触发了一系列复杂的局部或者全身的免疫炎症反应,引起多器官功能衰竭,发病率和病死率显著升高。由于至今仍然没有诊断脓毒症的金标准,所以脓毒症的临床诊断仍是一个难题。因此,脓毒症的临床诊断需要不断改变来满足临床和研究的要求。然而,尽管有许多新型的生物标记和筛选工具去预测脓毒症发生的风险,但是这些措施的诊断价值和有效性不足以让人满意,并且没有充分的证据去建议临床使用这些新技术。因此,脓毒症的临床诊断标准需要定期更新去适应不断产生的新证据。这篇综述旨在呈现当前脓毒症的诊断和早期识别方面的最新研究证据。临床运用不同的诊断方法的推荐意见依赖于推荐、评价、发展和评估分级体系(Grades of Recommendation Assessment,Development and Evaluation,GRADE),因为大部分的研究是观察性研究,并没有对这些方法进行可靠评估,采用的是两步推理方法。未来需要更多研究来确认或者反驳某一特殊的指标检测,同时应该直接采用相关病人的结果数据。 | Zhongheng Zhang Nathan J.Smischney Haibo Zhang Sven Van Poucke Panagiotis Tsirigotis Jordi Rello Patrick M.Honore Win Sen Kuan Juliet June Ray Jiancang Zhou You Shang Yuetian Yu Christian Jung Chiara Robba Fabio Silvio Taccone Pietro Caironi David Grimaldi Stefan Hofer George Dimopoulos Marc Leone Sang-Bum Hong Mabrouk Bahloul Laurent Argaud Won Young Kim Herbert D.Spapen Jose Rodolfo Rocco 张建成(译) 尚游(译) 钟鸣(校) | 2016 | 临床与病理杂志2016,36,10: | 5 |
| 4 | A Lookahead Read Cache: Improving Read Performance for Deduplication Backup Storage显示文摘数据 deduplication (dedupe 为短) 是一种特殊数据压缩技术。节省备份时间以及存储空间广泛地被采用了,特别地在备份存储系统。因此,大多数 dedupe 研究首先集中了于改进 dedupe 写性能。然而,备份存储 dedupe 读了性能也是为存储恢复的一个关键问题。新 dedupe 存储读了的图案为改善的备份应用程序缓冲的这篇论文由利用一个特殊特征读了性能:读的顺序与 write 顺序一样。为更好的缓存利用,由在一个动人的窗口以内向前寻找未来引用,因而,它从有最小的未来存取的缓存驱逐牺牲品。而且,进一步改进读的缓存性能,贤明地缓冲未来存取数据块维持一个小日志缓冲区。有真实世界的备份工作量的广泛的实验证明建议读的缓存计划在多达 64.3% | Dongchul Park Ziqi Fan Young Jin Nam David H. C. Du | 2017 | Journal of Computer Science & Technology2017,32,1: | 4 |
| 5 | Putting things in place for fertilization: discovering roles for importin proteins in cell fate and spermatogenesis显示文摘Importin 蛋白质原来通过原子毛孔在蛋白质运输为他们的中央角色被描绘,唯一的细胞内部的入口到原子核。这个重要函数必须紧被调整由抄写因素和另外的原子蛋白质控制存取到 genomic DNA,到完成细胞的行为影响的适当调整房间命运。调停 Importin 的 nucleocytoplasmic 运输依靠他们货物的特定的识别,与到不同、重叠的蛋白质子集的每 importin 绑定。importin 功能的知识关于三个关键发展系统实质地膨胀了:胚胎的干细胞,肌肉房间和细菌排队。自从为调整 nucleocytoplasmic 运输的潜力被建议贡献精子发生,在十年,我们和其它证明了进原子核的渡船抄写因素执行的 importins 另外的角色,它控制房间命运。这评论从哺乳动物的精子发生的研究介绍关键调查结果揭示男富饶和不孕由产生的潜在的新小径。germline 开始的这些研究照亮 importin 蛋白质在管理细胞的区别的新方法,经由指导到不同细胞内部的分隔空间并且由决定细胞的压力回答的蛋白质包括。 | Kate L Loveland Andrew T Major Romaly Butler Julia C Young David A Jan Yoichi Miyamoto | 2015 | Asian Journal of Andrology2015,17,4: | 3 |
| 6 | Scientific evidence is just the starting point: A generalizable process for developing sports injury prevention interventions显示文摘Background: The 2 most cited sports injury prevention research frameworks incorporate intervention development, yet little guidance is available in the sports science literature on how to undertake this complex process. This paper presents a generalizable process for developing implementable sports injury prevention interventions, including a case study applying the process to develop a lower limb injury prevention exercise training program(Footy First) for community Australian football.Methods: The intervention development process is underpinned by 2 complementary premises:(1) that evidence-based practice integrates the best available scientific evidence with practitioner expertise and end user values and(2) that research evidence alone is insufficient to develop implementable interventions.Results: The generalizable 6-step intervention development process involves(1) compiling research evidence, clinical experience, and knowledge of the implementation context;(2) consulting with experts;(3) engaging with end users;(4) testing the intervention;(5) using theory; and(6)obtaining feedback from early implementers. Following each step, intervention content and presentation should be revised to ensure that the final intervention includes evidence-informed content that is likely to be adopted, properly implemented, and sustained over time by the targeted intervention deliverers. For Footy First, this process involved establishing a multidisciplinary intervention development group, conducting 2targeted literature reviews, undertaking an online expert consensus process, conducting focus groups with program end users, testing the program multiple times in different contexts, and obtaining feedback from early implementers of the program.Conclusion: This systematic yet pragmatic and iterative intervention development process is potentially applicable to any injury prevention topic across all sports settings and levels. It will guide researchers wishing to undertake intervention development. | Alex Donaldson David G.Lloyd Belinda J.Gabbe Jill Cook Warren Young Peta White Caroline F.Finch | 2016 | Journal of Sport and Health Science2016,5,3: | 3 |
| 7 | High Prevalence of Sessile Serrated Adenomas With BRAF Mutations: A Prospective Study of Patients Undergoing Colonoscopy显示文摘 | Kevin J. Spring Zhen Zhen Zhao Rozemary Karamatic Michael D. Walsh Vicki L.J. Whitehall Tanya Pike Lisa A. Simms Joanne Young Michael James Grant W. Montgomery Mark Appleyard David Hewett Kazutomo Togashi Jeremy R. Jass Barbara A. Leggett | 2006 | Gastroenterology2006,,5: | 3 |
| 8 | Cell:癌基因“遗传平衡”或会影响患者对癌症疗法的反应显示文摘进行癌症疗法的选择越来越需要确定肿瘤细胞中是否含有一些特殊突变的癌基因会驱动癌细胞异常生长。并且确定是否癌细胞会对特殊药物耐受或敏感.近日来自加州大学旧金山分校的研究人员就通过研究发现。以常见的癌基因KRAs突变为例。患者对疗法的反应往往会随着肿瘤的不断进化而发生改变。相关研究刊登于国际杂志Cell上。 | Michael R. Burgess Eugene Hwang Rana Mroue Craig M. Bielski Anica M. Wandler Benjamin J. Huang Ari J. Firestone Amy Young Jennifer A. Lacap Lisa Crocker Saurabh Asthana Elizabeth M. Davis Jin Xu Keiko Akagi Michelle M. Le Beau Qing Li Benjamin Haley David Stokoe Deepak Sampath Barry S. Taylor Marie Evangelista Kevin Shannon | 2017 | 现代生物医学进展2017,17,18: | 2 |
| 9 | Collateral Flow Predicts Response to Endovascular Therapy for Acute Ischemic Stroke显示文摘 | Oh Young Bang Jeffrey L. Saver Suk Jae Kim Gyeong-Moon Kim Chin-Sang Chung Bruce Ovbiagele Kwang Ho Lee David S. Liebeskind | 2011 | Stroke2011,,3: | 2 |
| 10 | The synthetic rock mass approach for jointed rock mass modelling显示文摘 | Diego Mas Ivars Matthew E. Pierce Caroline Darcel Juan Reyes-Montes David O. Potyondy R. Paul Young Peter A. Cundall | 2010 | International Journal of Rock Mechanics and Mining Sciences2010,,2: | 2 |
| 11 | Association analysis using SSR markers to find QTL for seed protein content in soybean显示文摘 | Tae-Hwan Jun Kyujung Van Moon Young Kim Suk-Ha Lee David R. Walker | 2008 | Euphytica2008,,2: | 2 |
| 12 | Temperature and water vapour effects on the cyclic oxidation behaviour of Fe–Cr alloys显示文摘 | Norinsan K. Othman Jianqiang Zhang David J. Young | 2010 | Corrosion Science2010,,9: | 2 |
| 13 | Physicochemical and Biological Properties of Biomimetic Mineralo‐Protein Nanoparticles Formed Spontaneously in Biological Fluids显示文摘 | Hsin‐Hsin Peng Cheng‐Yeu Wu David Young Jan Martel Andrew Young David M. Ojcius Yu‐Hsiu Lee John D. Young | 2013 | Small2013,,13: | 1 |
| 14 | MUC17, a Novel Membrane-Tethered Mucin显示文摘 | James R. Gum Suzanne C. Crawley James W. Hicks David E. Szymkowski Young S. Kim | 2002 | Biochemical and Biophysical Research Communications2002,,3: | 1 |
| 15 | Association of Serum Bilirubin with Ischemic Stroke Outcomes显示文摘 | Sandra Pineda Oh Young Bang Jeffrey L. Saver Sidney Starkman Susan W. Yun David S. Liebeskind Doojin Kim Latisha K. Ali Samir H. Shah Bruce Ovbiagele | 2008 | Journal of Stroke and Cerebrovascular Diseases2008,,3: | 1 |
| 16 | Bevacizumab Maintenance in Patients with Advanced Non–Small-Cell Lung Cancer, Clinical Patterns, and Outcomes in the Eastern Cooperative Oncology Group 4599 Study: Results of An Exploratory Analysis显示文摘 | Ariel Lopez-Chavez Todd Young Sophie Fages Larry Leon Joan H. Schiller Afshin Dowlati Julie R. Brahmer David H. Johnson Alan Sandler | 2012 | Journal of Thoracic Oncology2012,,11: | 1 |
| 17 | Role for adrenal venous sampling in primary aldosteronism显示文摘 | William F. Young Anthony W. Stanson Geoffrey B. Thompson Clive S. Grant David R. Farley Jon A. van Heerden | 2004 | Surgery2004,,6: | 1 |
| 18 | Regional brain sodium, potassium and water changes in the rat middle cerebral artery occlusion model of ischemia显示文摘 | Young W Harry R David J | 1987 | Stroke1987,18,5: | 1 |
| 19 | The Future Prospects of Microbial Cel|u- lose in Biomedical Applications显示文摘 | Wojciech K Czaja David J Young Marek Kawec- ki | 2007 | Biomacromol- ecules2007,8,1: | 1 |
| 20 | Amplitude spectrum area: Measuring the probability of successful defibrillation as applied to human data显示文摘 | Clayton Young Joe Bisera Stacy Gehman David Snyder Wanchun Tang Max Harry Weil | 2004 | Critical Care Medicine . 2004 (9 Su)2004,,9: | 1 |