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| 1 | Human monoclonal antibodies block the binding of SARS-CoV-2 spike protein to angiotensin converting enzyme 2 receptor显示文摘According to the World Health Organization(WHO)newly updated situation report on March 18th,2020,the coronavirus disease 2019(COVID-19)pandemic has confirmed 191,127 cases and claimed 7807 deaths worldwide.1 The etiological agent of COVID-19 has been identified as a novel coronavirus,the severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),belonging to Sarbecovirus subgenus(genus Betacoronavirus,family Coronaviridae)and showing 79.6 and 96.2%sequence identity in nucleotide to SARS-CoV and a bat coronavirus(BatCoV RaTG13),respectively.2–4 Like SARS-CoV infection,a substantial fraction of COVID-19 patients exhibits severe respiratory symptoms and has to be hospitalized in intensive care unit.5–8 Although the mortality rate of COVID-19 is significantly lower than that of SARS-CoV infection,SARS-CoV-2 shows much higher human-to-human transmission rate,rapidly leading to a global pandemic declared by WHO on March 11th,2020. | Xiangyu Chen Ren Li Zhiwei Pan Chunfang Qian Yang Yang Renrong You Jing Zhao Pinghuang Liu Leiqiong Gao Zhirong Li Qizhao Huang Lifan Xu Jianfang Tang Qin Tian Wei Yao Li Hu Xiaofeng Yan Xinyuan Zhou Yuzhang Wu Kai Deng Zheng Zhang Zhaohui Qian Yaokai Chen Lilin Ye | 2020 | Cellular & Molecular Immunology2020，17，6： | 17 |
| 2 | Intelligent control of mode-locked femtosecond pulses by time-stretch-assisted real-time spectral analysis显示文摘Mode-locked fiber lasers based on nonlinear polarization evolution can generate femtosecond pulses with different pulse widths and rich spectral distributions for versatile applications through polarization tuning.However,a precise and repeatable location of a specific pulsation regime is extremely challenging.Here,by using fast spectral analysis based on a time-stretched dispersion Fourier transform as the spectral discrimination criterion,along with an intelligent polarization search algorithm,for the first time,we achieved real-time control of the spectral width and shape of mode-locked femtosecond pulses;the spectral width can be tuned from 10 to 40 nm with a resolution of ~1.47 nm,and the spectral shape can be programmed to be hyperbolic secant or triangular.Furthermore,we reveal the complex,repeatable transition dynamics of the spectrum broadening of femtosecond pulses,including five middle phases,which provides deep insight into ultrashort pulse formation that cannot be observed with traditional mode-locked lasers. | Guoqing Pu Lilin Yi Li Zhang Chao Luo Zhaohui Li Weisheng Hu | 2020 | Light(Science & Applications)2020，9，1： | 16 |
| 3 | rMVP: A Memory-efficient, Visualization-enhanced, and Parallel-accelerated Tool for Genome-wide Association Study显示文摘Along with the develoipment of high-throughput sequencing technologies,both sample size and SNP number are increasing rapidly in genome-wide association studies(GWAS),and the associated computation is more challenging than ever.Here,we present a memory-efficient,visualization-enhanced,and parallel-accelerated R package called“r MVP”to address the need for improved GWAS computation.r MVP can 1)effectively process large GWAS data,2)rapidly evaluate population structure,3)efficiently estimate variance components by Efficient Mixed-Model Association e Xpedited(EMMAX),Factored Spectrally Transformed Linear Mixed Models(Fa ST-LMM),and Haseman-Elston(HE)regression algorithms,4)implement parallel-accelerated association tests of markers using general linear model(GLM),mixed linear model(MLM),and fixed and random model circulating probability unification(Farm CPU)methods,5)compute fast with a globally efficient design in the GWAS processes,and 6)generate various visualizations of GWASrelated information.Accelerated by block matrix multiplication strategy and multiple threads,the association test methods embedded in r MVP are significantly faster than PLINK,GEMMA,and Farm CPU_pkg.r MVP is freely available at http://gffzz188fe103f8f1460aso0wx5pucqbfp6bcq.ffgz.tsg.suse.edu.cn/xiaolei-lab/r MVP. | Lilin Yin Haohao Zhang Zhenshuang Tang Jingya Xu Dong Yin Zhiwu Zhang Xiaohui Yuan Mengjin Zhu Shuhong Zhao Xinyun Li Xiaolei Liu | 2021 | Genomics, Proteomics & Bioinformatics2021，19，4： | 12 |
| 4 | Small interfering RNA targeted to secretory clusterin blocks tumor growth, motility, and invasion in breast cancer显示文摘Clusterin/apolipoprotein J (Clu ) 是在几个生理的过程被含有的无所不在地表示的分泌 heterodimeric glycoprotein。这被报导了分泌 clusterin (sClu ) 的提高的水平蛋白质在乳癌病人与差的幸存被联系并且能在啮齿类动物模型导致转移。在这研究,我们在 vitro 并且在 vivo 在细胞活动性,侵略,和生长上与小介入 RNA (siRNAs ) 调查了 sClu 抑制的效果。MDA-MB-231 房间是有 pSuper-siRNA/sClu 的 transfected。房间幸存和增长被 3-(4,5-dimethyl-thiazol-2yl ) 检验 -5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium 和 clonogenic 幸存试金。结果证明 sClu silencing 显著地禁止了 MDA-MB-231 房间的增长。侵略和迁居能力戏剧性地也被减少,它被 matrigel 试金检测。染色的 TUNEL 和 caspase-3 活动试金证明 sClu silencing 能也增加房间的 apoptosis 率,导致房间生长的抑制。我们也在一个 orthotopic 乳癌模型在肿瘤生长和变形前进上决定了 sClu silencing 的效果。结果比肿瘤源于父母 MDA-MB-231 或 MDA-MB-231/pSuper 的证明主要肿瘤从 MDA-MB-231/pSuper sClu siRNA 房间导出的 orthotopic 变得显著地慢爬 siRNA 房间,并且少些转移到肺。这些数据建议能分泌的 clusterin 在肿瘤生长和变形前进起一个重要作用。敲门下面 sClu 基因表示可以为乳癌治疗提供一个珍贵方法。 | Zhaohe Niu Xinhui Li Bin Hu Rong Li Ligang Wang Lilin Wu Xingang Wang | 2012 | Acta Biochimica et Biophysica Sinica2012，44，12： | 6 |
| 5 | The histone methyltransferase EZH2 primes the early differentiation of follicular helper T cells during acute viral infection显示文摘Epigenetic modifications to histones dictate the differentiation of naïve CD4^(+) T cells into different subsets of effector T helper(TH)cells.The histone methyltransferase enhancer of zeste homolog 2(EZH2)has been implicated in the mechanism regulating the differentiation of TH1,TH2 and regulatory T(Treg)cells.However,whether and how EZH2 regulates follicular helper T(TFH)cell differentiation remain unknown.Using a mouse model of acute lymphocytic choriomeningitis virus(LCMV)infection,we observed abundant EZH2 expression and associated H3K27me3 modifications preferentially in the early committed virus-specific TFH cells compared to those in TH1 cells.Ablation of EZH2 in LCMV-specific CD4^(+) T cells leads to a selective impairment of early TFH cell fate commitment,but not late TFH differentiation or memory TFH maintenance.Mechanistically,EZH2 specifically stabilizes the chromatin accessibility of a cluster of genes that are important for TFH fate commitment,particularly B cell lymphoma 6(Bcl6),and thus directs TFH cell commitment.Therefore,we identified the chromatin-modifying enzyme EZH2 as a novel regulator of early TFH differentiation during acute viral infection. | Xiangyu Chen Guoshuai Cao Jialin Wu Xinxin Wang Zhiwei Pan Jianbao Gao Qin Tian Lifan Xu Zhirong Li Yaxing Hao Qizhao Huang Pengcheng Wang Minglu Xiao Luoyingzi Xie Shupei Tang Zhenyu Liu Li Hu Jianfang Tang Ran He Li Wang Xinyuan Zhou Yuzhang Wu Mengjie Chen Beicheng Sun Bo Zhu Jun Huang Lilin Ye | 2020 | Cellular & Molecular Immunology2020，17，3： | 4 |
| 6 | Automatic mode-locking fiber lasers: progress and perspectives显示文摘Polarization control in nonlinear polarization rotation based mode-locked fiber lasers is a longterm challenge.Suffering from the polarization drifts induced by environmental disturbances,nonlinear polarization rotation based mode-locked fiber lasers is difficult in continuously operating under the desired pulsation regime thereby substantially hindering their utilizations.The appearance of automatic modelocking techniques brings the light in addressing this challenge.Combining with various algorithms and electrical polarization control,automatic mode-locking techniques resolve the dilemma of nonlinear polarization rotation based mode-locked fiber lasers.We review the research progress of automatic mode-locking techniques in detail.Furthermore,we comment on the perspectives and potential applications of automatic mode-locking techniques. | Guoqing PU Li ZHANG Weisheng HU Lilin YI | 2020 | Science China(Information Sciences)2020，63，6： | 4 |
| 7 | A Low-Interference Time-Domain N-Continuous OFDM Scheme显示文摘N-continuous orthogonal frequency division multiplexing(NC-OFDM) is an outstanding method to suppress sidelobe for baseband OFDM signals in future 5G wireless communications.However,the precoder of NCOFDM usually causes severe interference and high complexity.To alleviate these problems,this paper proposes an improved time-domain N-continuous OFDM(TD-NC-OFDM) by optimizing the smooth signal,which is the linear combination of rectangularly pulsed OFDM basis signals truncated by a smooth window.Furthermore,we show that the proposed scheme is with lower transceiver complexity and notable performance gain in signal-tointerference-plus-noise ratio(SINR).Lastly,simulation results show that the proposed low-interference TD-NC-OFDM can achieve similar sidelobe suppression performance,with negligible bit-error rate(BER) degradation,compared to conventional NC-OFDM. | Peng Wei Lilin Dan Yue Xiao Xia Lei Shaoqian Li | 2016 | China Communications2016，13，S2： | 3 |
| 8 | Porcine FcεRI Mediates Porcine Reproductive and Respiratory Syndrome Virus Multiplication and Regulates the Inflammatory Reaction显示文摘Porcine reproductive and respiratory syndrome virus(PRRSV) shows characteristic antibody-dependent enhancement(ADE) of infection and causes porcine systemic inflammation, which is similar to a type I allergic reaction; however, the role of porcine FceεRI in ADE is still unclear. In this study, the expression of different Fc receptors(Fc Rs) on macrophages was investigated in a PRRSV 3D4/21 cell infection model in the presence or absence of PRRSV antibody. The transcription level of Fcc II and FceεRI was significantly up-regulated under PRRSV-antibody complex infection. Internalization and proliferation of PRRSV were promoted by the ADE mechanism when FceεRI was expressed in permissive 3D4/21 cells and the non-permissive cell line HEK 293T. Transcriptome sequencing data showed that the expression levels of AKT,ERK and other signal molecules in the anti-inflammatory pathway were significantly increased, especially in the cells infected with the PRRSV-antibody immune complex. Inflammatory regulatory molecules such as PLA2G6, LOX, TRPM8 and TRPM4 were significantly up-regulated following PRRSV infection but significantly down-regulated in the cells infected with the PRRSV-antibody immune complex. Our results demonstrated that FceεRI could be involved in PRRSV ADE, the antigen presenting process and regulation of the inflammatory response during PRRSV infection, which provides new insights into PRRSV infection mediated by FceεRI and the PRRSV-antibody immune complex. | Peidian Shi Lilin Zhang Jiashun Wang Dong Lu Yi Li Jie Ren Menglu Shen Lei Zhang Jinhai Huang | 2018 | Virologica Sinica2018，33，3： | 3 |
| 9 | Fabrication and application of a graphene polarizer with strong saturable absorption显示文摘By transferring 100 nm gold-coated CVD monolayer graphene onto the well-polished surface of D-shaped fiber, we achieve a graphene in-line polarizer with a high polarization extinction ratio of ~27 d B and low insertion loss of 5 d B at 1550 nm, meanwhile achieving a strong saturable absorption effect of 14%. The manufacture of this graphene in-line polarizer also simplifies the graphene transfer process. To explore the potential applications of the new device, we also demonstrate noise-like pulse generation and supercontinuum spectrum generation. By launching the designed graphene device into a fiber ring laser cavity, 51 nm bandwidth noise-like pulse is obtained. Then, launching the high-power noise-like pulse into high nonlinear fiber, a 1000 nm wide supercontinuum spectrum is obtained, which is favorable for sensing and nonlinearities scientific fields. | Weixiong Li Lilin Yi Ran Zheng Zhenghua Ni Weisheng Hu | 2016 | Photonics Research2016，4，2： | 2 |
| 10 | SOME RESULTS OF UPPER ATMOSPHERIC COMPOSITION MEASUREMENTS BY A MASS-SPECTROMETER ON BOARD 'SZ-2':CHANGE OF COMPOSITIONS DURING SOLAR AND GEOMAGNETIC DISTURBANCES显示文摘Upper atmosphere composition data were obtained for the last half year with a quadruple mass spectrometer on board spacecraft 'SZ-2' launched on 10 Jan uary 2001. Based on the analysis of these data, the variations of atmospheric compositions in solar and geomagnetic quiet conditions are reported first, then a detailed discussion on the atmospheric composition variations under the so lar and geomagnetic disturbed conditions is given. The results show that near the altitude of 400 km the variations of main atmospheric compositions corre sponding to solar disturbances are more remarkable in the sunlit area than in the shade area. On the contrary, in geomagnetic disturbance events the corre sponding variations are more obvious in the shade area, an evident increase of N2 density at relatively higher latitudes was observed. | QIN Guotai QIU Shiyan HE Aiqing ZHU Yiqiang SUN Lilin LIN Xianwen LI Hong XU Xuepei | 2002 | 空间科学学报2002，22，z1： | 2 |
| 11 | Performance analysis of peak cancellation in OFDM systems显示文摘Peak cancellation is a class of peak-to-average power ratio (PAPR) reduction techniques for orthogo-nal frequency division multiplexing (OFDM).It can control the PAPR and out-of-band radiation simultaneously at the cost of additional interference.In this paper,the interference of peak cancellation is modeled and an-alyzed so as to evaluate the degradation of system performance.Furthermore,through theoretical analysis,a closed form of the BER performance is derived for OFDM with popular modulation schemes such as QPSK and 16QAM.Finally,the analytical results are verified by simulations. | XIAO Yue BAI WenLing DAN LiLin WU Gang LI ShaoQian | 2012 | Science China(Information Sciences)2012，55，4： | 2 |
| 12 | The dichotomous and incomplete adaptive immunity in COVID-19 patients with different disease severity显示文摘The adaptive immunity that protects patients from coronavirus disease 2019(COVID-19),caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),is not well characterized.In particular,the asymptomatic patients have been found to induce weak and transient SARS-CoV-2 antibody responses,but the underlying mechanisms remain unknown;meanwhile,the protective immunity that guide the recovery of these asymptomatic patients is elusive.Here,we characterized SARS-CoV-2-specific B-cell and T-cell responses in 10 asymptomatic patients and 64 patients with other disease severity(mild,n=10,moderate,n=32,severe,n=12)and found that asymptomatic or mild symptomatic patients failed to mount virus-specific germinal center(GC)B cell responses that result in robust and prolonged humoral immunity,assessed by GC response indicators including follicular helper T(TFH)cell and memory B cell responses as well as serum CXCL13 levels.Alternatively,these patients mounted potent virus-specific TH1 and CD8+T cell responses.In sharp contrast,patients of moderate or severe disease induced vigorous virus-specific GC B cell responses and associated TFH responses;however,the virus-specific TH1 and CD8+T cells were minimally induced in these patients.These results,therefore,uncovered the protective immunity in asymptomatic patients and also revealed the strikingly dichotomous and incomplete humoral and cellular immune responses in COVID-19 patients with different disease severity,providing important insights into rational design of effective COVID-19 vaccines. | Leiqiong Gao Jing Zhou Sen Yang Lisha Wang Xiangyu Chen Yang Yang Ren Li Zhiwei Pan Jing Zhao Zhirong Li Qizhao Huang Jianfang Tang Li Hu Pinghuang Liu Guozhong Zhang Yaokai Chen Lilin Ye | 2021 | Signal Transduction and Targeted Therapy2021，6，4： | 2 |
| 13 | The C/EBPβ-Dependent Induction of TFDP2 Facilitates Porcine Reproductive and Respiratory Syndrome Virus Proliferation显示文摘Porcine reproductive and respiratory syndrome(PRRS) is an important infectious disease caused by porcine reproductive and respiratory syndrome virus(PRRSV), leading to significant economic losses in swine industry worldwide. Although several studies have shown that PRRSV can affect the cell cycle of infected cells, it is still unclear how it manipulates the cell cycle to facilitate its proliferation. In this study, we analyzed the mRNA expression profiles of transcription factors in PRRSV-infected 3D4/21 cells by RNA-sequencing. The result shows that the expression of transcription factor DP2(TFDP2) is remarkably upregulated in PRRSV-infected cells. Further studies show that TFDP2 contributes to PRRSV proliferation and the PRRSV nucleocapsid(N) protein induces TFDP2 expression by activating C/EBPb. TFDP2 positively regulates cyclin A expression and triggers a less proportion of cells in the S phase, which contributes to PRRSV proliferation. This study proposes a novel mechanism by which PRRSV utilizes host protein to regulate the cell cycle to favor its infection. Findings from this study will help us for a better understanding of PRRSV pathogenesis. | Min Zhu Xiaoyang Li Ruiqi Sun Peidian Shi Aiping Cao Lilin Zhang Yanyu Guo Jinhai Huang | 2021 | Virologica Sinica2021，36，6： | 2 |
| 14 | CD49a^(+)CD49b^(+) NK cells induced by viral infection reflect an activated state of conventional NK cells显示文摘Natural killer(NK) cells are important innate effectors that play a pivotal role in the defense against tumors and infections and participate in regulating adaptive immunity. Recent studies have revealed phenotypic and functional heterogeneity of NK cells.Here, using murine models of acute and chronic lymphocytic choriomeningitis virus infection, we observed that a CD49a^(+)CD49b^(+) NK cell subset emerged in the liver and other tissues, and underwent vigorous expansion following viral infection,before progressively decreasing in cell number. These viral infection-induced CD49a^(+)CD49b^(+) NK cells displayed an activated and mature phenotype. Moreover, compared with liver-resident NK cells and conventional NK(cNK) cells, CD49a^(+)CD49b^(+) NK cells showed increased functional competence, as evidenced by higher amounts of IFN-γ production and stronger cytotoxic capabilities during viral infection. Generation of these CD49a^(+)CD49b^(+) NK cells was shown to be independent of the T-bet transcription factor. Adoptive transfer experiments revealed that c NK cells could convert into CD49a^(+)CD49b^(+) NK cells following viral infection. Collectively, these results suggest that viral infection-induced CD49a^(+)CD49b^(+) NK cells represent a transiently activated state of cNK cells. | Wenhan Li Jing Zhou Xianwei Wang Yuzhang Wu Lilin Ye Haiming Wei Rui Sun Zhigang Tian Hui Peng | 2020 | Science China(Life Sciences)2020，63，11： | 2 |
| 15 | Progress and Prospects of the Strategic Priority Program on Space Science显示文摘In May 2018,the second phase of the Strategic Priority Program on Space Science(SPP II)was officially approved by the Chinese Academy of Sciences,in view of the significant scientific achievements of the first phase of the Strategic Priority Program on Space Science(SPP I)which includes 4 space science missions:the Dark Matter Particle Explorer(DAMPE),ShiJian-10(SJ-10),Quantum Experiments at Space Scale(QUESS)and Hard X-ray Modulation Telescope(HXMT).Aiming to address fundamental scientific questions,SPP II focuses on two major themes:How the universe and life originate and evolve and What is the relationship between the solar system and human beings.In areas that Chinese scientists have advantages,new space science missions including Graviational wave high-energy Electromagnetic Counterpart All-sky Monitor(GECAM),the Advanced space-based Solar Observatory(ASO-S),the Einstein Probe(EP),and Solar wind Magnetosphere Ionosphere Link Explorer(SMILE)have been approved in the framework of SPP II.This paper presents the research highlights of the SPP I,introduces the recent progress of SPP II,and puts forward the prospects for future development. | WANG Chi SUN Lilin FAN Quanlin LI Chao BAI Qingjiang | 2020 | 空间科学学报2020，40，5： | 2 |
| 16 | Retrorsine Cooperates with Gut Microbiota to Promote Hepatic Sinusoidal Obstruction Syndrome by Disrupting the Gut Barrier显示文摘Background and Aims:Hepatic sinusoidal obstruction syndrome(HSOS)is a life-threatening syndrome,and a cause is exposure to pyrrolizidine alkaloid(PA)-containing products.It is well-established that retrorsine(RTS),a rep-resentative Pas,insults hepatic sinusoidal endothelial cells and ensues congestion of hepatic sinusoids.However,little known about the impact of Pas on gut microbiota and intesti-nal barrier and inflammation in HSOS.Methods:Mice were gavaged with or without nonabsorbable antibiotics(ABX),followed by a single dose of RTS.The gut microbiota was examined by 16S rDNA sequencing.Results:ABX pretreat-ment significantly reversed RTS-induced liver damage.RTS altered gut microbiota composition,increasing Gram-nega-tive bacteria and resulting in a sharp elevation of circulating lipopolysaccharides(LPS)in HSOS mice.Gut decontamina-tion with ABX alleviated RTS-induced intestine inflamma-tion,protected against disruption of the intestinal epithelial barrier and gut vascular barrier(GVB),and suppressed he-patic LPS-NF-κB pathway activation in RTS-induced HSOS.Importantly,the LPS level was positively correlated with MELD score in patients with HSOS.Elevated LPS in patients with HSOS confirmed that Gram-negative bacteria were in-volved in the pathogenesis of HSOS.Conclusions:RTS,a PA,cooperated with gut dysbiosis to cause intestinal inflam-mation and gut barrier compromise that increased transport of gut-derived LPS into the liver through the portal vein,which contributed to the pathology of HSOS.Modulating the gut microbiota,protecting the intestinal barrier,and sup-pressing intestinal inflammation with prebiotics or antibiot-ics might be a useful pharmacologic intervention in HSOS. | Li Xiao Lilin Hu Huikuan Chu Liuying Chen Jingjing Yan Weijun Wang Xiaoqian Yang Qingjing Zhu Fan Du Yuhu Song Peng Chen Xiaohua Hou Ling Yang | 2022 | Journal of Clinical and Translational Hepatology2022，10，6： | 2 |
| 17 | Elevation gradient distribution of indices of tree population in a montane forest:The role of leaf traits and the environment显示文摘Background:To disentangle the controls on species distribution in the context of climate change is a central element in proposed strategies to maintain species diversity.However,previous studies have focused mainly on the roles of abiotic factors(e.g.,climate and soil properties),with much less attention given to the roles of biotic factors such as functional traits.Here,we measured eight leaf traits for 240 individual trees of 53 species and analyzed the variation in traits and population composition indices and their relationships with soil properties,climate factors,and leaf traits.Results:The tree density,frequency and species importance values of the overall species and saplings significantly increased with increasing elevation,while the same indices(except for species frequency)of adults did not significantly change.The largest percentage of variation of species importance value(greater than 50%)was explained by climate,but leaf traits played a critical role in driving elevation distribution patterns of both saplings and adults;the abundance of saplings significantly increased with elevation,with increased leaf carbon contents,while the abundance of adults did not change in accordance with a nutrient conservation strategy associated with the leaf economic spectrum.Conclusions:Our results suggest that the elevation gradient distribution of woody plant species is dependent on tree size and that local atmospheric humidity and leaf traits cause considerable variation in species distribution along subtropical mountain elevations.We provide evidence of which leaf traits play a key role in the elevation gradient distribution of different sizes of woody tree species. | Zuhua Wang Rong Zheng Lilin Yang Tinghong Tan Haibo Li Min Liu | 2022 | Forest Ecosystems2022，9，1： | 1 |
| 18 | Lipase--catalyzed trans- esterifieation of rapeseed oils for biodiesel production with a novel or ganic solvent as the reaction medium 显示文摘 | Lilin Li Wei Du Dehua Liu | 2006 | Journal of Molecular Catalysis B : Enzymatic2006，43，： | 1 |
| 19 | A low-complexity multiple signal representation scheme in downlink OFDM-CDMA显示文摘OFDM-CDMA is an attractive technique for broadband wireless communication. However, the high peakto-average power ratio (PAPR) of the downlink signals, generated from multiple spread codes, remains a serious problem. In this paper, a low-complexity multiple signal representation (MSR) scheme is proposed to control the PAPR problem in downlink OFDM-CDMA systems. The proposed scheme generates multiple candidate signals by a novel user grouping scheme, which is without distortion and can provide more PAPR reduction than the conventional MSR schemes, such as partial transmit sequence (PTS) and selective mapping (SLM). Furthermore, a low-complexity processing structure is developed using a novel joint spreading and inverse fast Fourier transform (S-IFFT) to simplify the generation of multiple candidate signals. Complexity analysis and numerical results show that the OFDM-CDMA systems employing the proposed scheme have better tradeoff between PAPR reduction and computational complexity, compared with the conventional MSR schemes. | DAN LiLin XIAO Yue CHENG Peng WU Gang LI ShaoQian | 2009 | Science in China(Series F)2009，52，12： | 1 |
| 20 | Growing impacts of low-flow events on vegetation dynamics in hydrologically connected wetlands downstream Yangtze River Basin after the operation of the Three Gorges Dam显示文摘Wetland vegetation is intimately related to floodplain inundations,which can be seriously affected by dam operation.Poyang Lake is the largest floodplain wetland in China and naturally connected with the Yangtze River and the Three Gorges Dam(TGD)upstream.To understand the potential impacts of TGD on Poyang Lake wetlands,we collected remote sensing imagery acquired during dry season from 1987 to 2020 and extracted vegetation coverage data in the Ganjiang Northern-branch Delta(GND)and the Ganjiang Southern-branch Delta(GSD),using the Object-oriented Artificial Neural Network Regression.Principal components analysis,correlation analysis,and the random forest model were used to explore the interactions between vegetation extent in the two deltas and 33 hydrological variables regarding magnitude,duration,timing,and variation.The implementation of the TGD advanced and extended the low-flow periods in Poyang Lake.Vegetation coverage in the GND and GSD increased at the rates of 0.39 and 0.22 km2/year,respectively.The reservoir storage at the end of September accelerated the runoff recession in the GND and the GSD,making low-flow events more influential for vegetation dynamics and shortening the response time of vegetation to the water regime.This study provides an important reference for evaluating the impacts of dam engineering on downstream wetlands. | WANG Dandan LIU Ying ZHENG Lilin LI Dahui | 2023 | Journal of Geographical Sciences2023，33，4： | 1 |
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