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| 1 | Noncontrast-enhanced MRI-based Noninvasive Score for Portal Hypertension(CHESS1802):An International Multicenter Study显示文摘Background and Aims:This study aimed to determine the performance of the non-invasive score using noncontrastenhanced MRI(CHESS-DIS score)for detecting portal hy-pertension in cirrhosis.Methods:In this international multicenter,diagnostic study(ClinicalTrials.gov,NCT03766880),patients with cirrhosis who had hepatic venous pressure gradient(HVPG)measurement and noncontrast-enhanced MRI were prospectively recruited from four university hospitals in China(n=4)and Turkey(n=1)between December 2018 and April 2019.A cohort of patients was retrospectively recruited from a university hospital in Italy between March 2015 and November 2017.After segmentation of the liver on fat-suppressed T1-weighted MRI maps,CHESS-DIS score was calculated automatically by an in-house developed code based on the quantification of liver surface nodularity.Results:A total of 149 patients were included,of which 124 were from four Chinese hospitals(training cohort)and 25 were from two international hospitals(validation cohort).A positive correlation between CHESS-DIS score and HVPG was found with the correlation coefficients of 0.36(p<0.0001)and 0.55(p<0.01)for the training and validation cohorts,respectively.The area under the receiver operating characteristic curve of CHESS-DIS score in detection of clinically significant portal hypertension(CSPH)was 0.81 and 0.9 in the training and validation cohorts,respectively.The intra-class correlation coefficients for assessing the inter-and intra-observer agreement were 0.846 and 0.841,respectively.Conclusions:A non-invasive score using noncontrast-enhanced MRI was developed and proved to be significantly correlated with invasive HVPG.Besides,this score could be used to detect CSPH in patients with cirrhosis. | Yanna Liu Tianyu Tang NecatiÖrmeci Yifei Huang Jitao Wang Xiaoguo Li Zhiwei Li Weimin An Dengxiang Liu Chunqing Zhang Changchun Liu Jinqiang Liu Chuan Liu Guangchuan Wang Cristina Mosconi Alberta Cappelli Antonio Bruno Seray Akçalar EmrecanÇelebioğlu EvrenÜstüner Sadık Bilgiç Zeynep Ellik ÖzgünÖmer Asiller Lei Li Haijun Zhang Ning Kang Dan Xu Ruiling He Yan Wang Yang Bu Ye Gu Shenghong Ju Rita Golfieri Xiaolong Qi | 2021 | Journal of Clinical and Translational Hepatology2021，9，6： | 3 |
| 2 | Dendrite morphology and evolution mechanism of nickel-based single crystal superalloys grown along the<001>and<011>orientations | Chubin Yang,Lin Liu n,Xinbao Zhao,Yafeng Li,Jun Zhang,Hengzhi Fu State Key Laboratory of Solidification Processing,Northwestern Polytechnical University,Xi’an 710072,China | 2012 | Progress in Natural Science:Materials International2012，22，5： | 2 |
| 3 | Multiple expansions of C4 plant biomass in East Asia since 7 Ma coupled with strengthened monsoon circulation 显示文摘 | An Z S Huang Y S Liu W G Guo Z T Clemens S Li L Prell W Ning Y F Cai Y J Zhou W J Lin B H Zhang Q L Cao Y N Qiang X K Chang H Wu Z K | 2005 | Geology2005，33，9： | 1 |
| 4 | 3-D dose distribution for stents, liquid balloons and ~(90)Y seeds using dose-volume histograms显示文摘 | Whiting JS Li AN Eigler N | 1997 | Med Phys1997，24，： | 1 |
| 5 | The synthesis and demulsification of two lower generation hyperbranehed polyether surfactants显示文摘 | Wang J Li C Q An N | 2012 | Separation Science and Technology2012，47，10： | 1 |
| 6 | Pseudorabies virus variant in Bartha-K61-vaccinated pigs,China,2012显示文摘 | An T Q Peng J M Tian Z J Zhao H Y Li N Liu Y M Chen J Z Leng C L Sun Y Chang D Tong G Z | 2013 | Emerg Infect Dis2013，19，11： | 1 |
| 7 | Did an extensive forest ever develop on the Chinese Loess Plateau during the past 130 ka?: A test using soil carbon isotopic signatures 显示文摘 | Liu W G Yang H Cao Y N Ning Y F Li Li Zhou Jie An Z S | 2005 | Appl Geochem2005，20，3： | 1 |
| 8 | Thesequence and de novo assembly of the giant panda genome显示文摘 | LI R FAN W TIAN G ZHU H HE L CAI J HUANG Q CAIQ LI B BAI Y ZHANG Z ZHANG Y WANG W LI J WEI F LI H JIAN M LI J ZHANG Z NIELSEN R LI D GU W YANG Z XUAN Z RYDER OA LEUNG FC ZHOU Y CAO J SUN X FU Y FANG X GUO X WANG B HOU R SHEN F MU B NI P LIN R QIAN W WANG G YU C NIE W WANGJ WU Z LIANG H MIN J WU Q CHENG S RUAN J WANGM SHI Z WEN M LIU B REN X ZHENG H DONG D COOKK SHAN G ZHANG H KOSIOL C XIE X LU Z ZHENG H LI Y STEINER CC LAM TT LIN S ZHANG Q LI G TIAN J GONG T LIU H ZHANG D FANG L YE C ZHANG J HU W XU A REN Y ZHANG G BRUFORD MW LI Q MA L GUOY AN N HU Y ZHENG Y SHI Y LI Z LIU Q CHEN Y ZHAO J QU N ZHAO S TIAN F WANG X WANG H XU L LIU X VINAR T WANG Y LAM TW YIU SM LIU S ZHANGH LI D HUANG Y WANG X YANG G JIANG Z WANG J QIN N LI L LI J BOLUND L KRISTIANSEN K WONG GK OLSON M ZHANG X LI S YANG H WANG J WANG J | 2010 | Na-ture2010，463，： | 1 |
| 9 | Review of HIV and Other Sexually Transmitted Infectious among Female Sex Workers in China显示文摘 | Poon AN Li Z Wang N Hong Y | 2012 | AIDS Care2012，，23： | 1 |
| 10 | 查看详情显示文摘 | Wang J Li C Q An N Yang Y | | 0，，10： | 1 |
| 11 | Emergence and localized circulation of a vaccine-derived poliovirus in an isolated mountain com- munity in Guangxi, China显示文摘 | Yan D Li L Zhu S Zhang Y An J Wang D Wen N Jorba J Liu W Zhong G Huang L Kew O Li- ang X Xu W | 2010 | J Clin Microbiol2010，48，9： | 1 |
| 12 | Macromolecules显示文摘 | Hu X An H N Li Z M Geng Y Li L B Yang C L | 2009 | 42:32152009，42，： | 1 |
| 13 | Review of HIV and other sexually transmitted infections among female sex workers in China显示文摘 | Poon AN Li Z Wang N | 2011 | AIDS Care2011，231，： | 1 |
| 14 | Review of HIV and other sexually transmitted infections among female sex workers in China 显示文摘 | POONM AN LI Z WANG N | 2011 | AIDS Care2011，，： | 1 |
| 15 | Location Planning for Transit-based Evacuation Under the Risk of Service Disruptions显示文摘 | AN S CUI N LI X P | | 0，，： | 1 |
| 16 | Up-regulation of key microRNAs,and inverse down-regulation of their predicted oxidative phosphorylation target genes,during aging in mouse brain显示文摘 | Li N Bates DJ An J | | 0，，： | 1 |
| 17 | Clinical and cytogenetic results of a series of amniocentesis cases from Northeast China: a re-port of 2500 cases显示文摘 | An N Li L L Wang R X | 2015 | Genet Mol Res2015，14，15： | 1 |
| 18 | Chlorotoxin-conjugated nanoparticles as potential glioma-targeted drugs 显示文摘 | Fu Y An N Li K | 2012 | J Neurooncol2012，107，3： | 1 |
| 19 | Differential Geochemical Features of Clinopyroxene from the Floodplain Sediments in Yangtze and Hanjiang Rivers and Its Implication for Detrital Source Identification显示文摘The evolution history of the Yangtze River attracted increasing attention in recent years. Comparison of the properties of the floodplain sediments between the upper and lower reaches of the Three Gorges is of significance to identify the material detrital sources for the Yangtze River Basin. Clinopyroxene(Cpx) is the typical mineral widely distributed in the sediments of the Yangtze River Basin. Cpx was extracted from the fine sediments with the grain size ranging from 0.063 to 0.125 mm in the upper and lower reaches of the Three Gorges. The sediments, from which the Cpx was extracted, were taken from the floodplains of the catchments of both the Yangtze River and the Hanjiang River, as well as from the surface of the Zhoulao Core drilled in the center of the Jianghan Basin where the two rivers flow through. Geochemistry of these Cpx was investigated, concerning the contents of major elements measured by electron probe microanalysis(EPMA) and the contents of trace elements analyzed by laser ablation inductively coupled plasma-mass spectrometry(LA-ICP-MS). The Cpx in the Yangtze River contains titaniferous augite which is sourced from the Panzhihua-Xichang region in South Sichuan Province, whereas the Cpx in the Hanjiang River is mainly from the surroundings without any titaniferous augite. The REE analysis infers that the titaniferous augite is the diagnostic mineral of the upper Yangtze River, and thus could be used as a tracer mineral to identify the detrital sources for the sediments formed during the evolution of the Yangtze River. The Cpx from the surface sediments of the Jianghan Plain(Zhoulao Core) shows comparable geochemical nature with that of the Yangtze River, but is different in geochemistry from that of the Hanjiang River, implying that the modern sediments in the Jianghan Plain are mainly sourced from the upper Yangtze River. | Jian Yang Chang'an Li Yufen Zhang N'dji dit Jacques Dembele | 2014 | Journal of Earth Science2014，25，4： | 1 |
| 20 | The Effect of Pressing Directionon the 5-axis CNC Incremental Forming Quality显示文摘 | ZHU H u LI N an LIU Zhijun | 2012 | International Journal of Material Forming2012，5，3： | 1 |
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