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| 1 | Ground settlement of Chek Lap Kok Airport,Hong Kong,detected by satellite synthetic aperture radar interferometry显示文摘Satellite synthetic aperture radar (SAR) inter-ferometry is used to investigate the slowly accumulating ground settlement at the new Chek Lap Kok Airport in Hong Kong. Most of the land occupied by the airport was reclaimed from the sea and therefore certain ground settlement in the area has been expected. A pair of ERS-2 SAR images spanning nearly a year is used in the study. The high spatial resolution (20 m×20 m) ground settlement map derived indicates that the settlement that occurred in the area over the time period is as large as 50 mm. The SAR measurement results agree with the levelling measurements at some benchmarks in the area to well within 1 cm(rms error),and the overall correlation between the two types of results is 0.89. The paper presents some brief background of inter-ferometric SAR, and outlines the data processing methods and results. | LIU Guoxiang DING Xiaoli CHEN Yongqi LI Zhilin LI Zhiwei | 2001 | Chinese Science Bulletin2001，46，21： | 16 |
| 2 | Interface issues of lithium metal anode for high-energy batteries: Challenges, strategies, and perspectives显示文摘Lithium(Li)metal is considered as one of the most promising anode materials for next-generation high-energy-density storage systems.However,the practical application of Li metal anode is hindered by interfacial instability and air instability due to the highly reactivity of Li metal.Unstable interface in Li metal batteries(LMBs)directly dictates Li dendrite growth,“dead Li”and low Coulombic efficiency,resulting in inferior electrochemical performance of LMBs and even safety issues.In addition,its sensitivity to ambient air leads to the severe corrosion of Li metal anode,high requirements of production and storage,and increased manufacturing cost.Plenty of efforts in recent years have overcome many bottlenecks in these fields and hastened the practical applications of high-energy-density LMBs.In this review,we focus on emerging methods of these two aspects to fulfill a stable and low cost electrode.In this perspective,design artificial solid electrolyte interphase(SEI)layers,construct three-dimensional conductive current collectors,optimize electrolytes,employ solid-state electrolytes,and modify separators are summarized to be propitious to ameliorate interfacial stability.Meanwhile,ex situ/in situ formed protective layers are highlighted in favor of heightening air stability.Finally,several possible directions for the future research on advanced Li metal anode are addressed. | Yiyao Han Bo Liu Zhen Xiao Wenkui Zhang Xiuli Wang Guoxiang Pan Yang Xia Xinhui Xia Jiangping Tu | 2021 | InfoMat2021，3，2： | 11 |
| 3 | The wheat MYB-related transcription factor TaMYB72 promotes flowering in rice显示文摘Through large-scale transformation analyses, Ta MYB72 was identified as a flowering time regulator in wheat. Ta MYB72 is a MYB family transcription factor localized to the nucleus. Three Ta MYB72 homologs,Ta MYB72-A, Ta MYB72-B and Ta MYB72-D, cloned from hexaploid wheat were mapped to the short arm of the group 6 chromosomes. Under the long-day conditions,over-expression of the Ta MYB72 in rice shortened the flowering time by approximately 12 d. Expression analyses suggest that Ta MYB72 may function through upregulation of florigen genes Hd3 a and RFT1. | Lichao Zhang Guoxiang Liu Jizeng Jia Guangyao Zhao Chuan Xia Lina Zhang Fu Li Qiang Zhang Chunhao Dong Shuangcheng Gao Longzhi Han Xiuping Guo Xin Zhang Jinxia Wu Xu Liu Xiuying Kong | 2016 | Journal of Integrative Plant Biology2016，58，8： | 8 |
| 4 | Medical expenditures for colorectal cancer diagnosis and treatment: A 10-year high-level-hospital-based multicenter retrospective survey in China, 2002-2011显示文摘Objective: Colorectal cancer(CRC) causes a substantial burden of disease in China and the evidence of economic burden triggered is fundamental for priority setting. The aim of this survey was to quantify medical expenditures and the time trends for CRC diagnosis and treatment in China.Methods: From 2012 to 2014, a hospital-based multicenter retrospective survey was conducted in 13 provinces across China. For each eligible CRC patient diagnosed from 2002 to 2011, clinical information and expenditure data were extracted using a uniform questionnaire. All expenditure data were reported in Chinese Yuan(CNY)using 2011 values.Results: Of the 14,536 CRC patients included, the average age at diagnosis was 58.2 years and 15.8% were stageI cases. The average medical expenditure per patient was estimated at 37,902 CNY [95 % confidence interval(95%CI): 37,282-38,522], and the annual average increase rate was 9.2% from 2002 to 2011(P for trend <0.001), with a cumulative increase of 2.4 times(from 23,275 CNY to 56,010 CNY). The expenditure per patient in stages Ⅰ, Ⅱ, Ⅲ and Ⅳ were 31,698 CNY, 37,067 CNY, 38,918 CNY and 42,614 CNY, respectively(P<0.001). Expenditure significantly differed within various subgroups. Expenses for drugs contributed the largest proportion(52.6%).Conclusions: These conservative estimates illustrated that medical expenditures for CRC diagnosis and treatment in tertiary hospitals in China were substantial and increased rapidly over the 10 years, with drugs continually being the main expense by 2011. Relatively, medical expenditures are lower for CRC in the earlier stages. These findings will facilitate the economic evaluation of CRC prevention and control in China. | Jufang Shi Guoxiang Liu Hong Wang Ayan Mao Chengcheng Liu Lanwei Guo Huiyao Huang Jiansong Ren Xianzhen Liao Yana Bai Xiaojie Sun Xinyu Zhu Jialin Wang Bingbing Song Jinyi Zhou Lin Zhu Haike Lei Yuqin Liu Yunyong Liu Lingbin Du Yutong He Kai Zhang Ni Li Wanqing Chen Min Dai Jie He | 2019 | Chinese Journal of Cancer Research2019，31，5： | 8 |
| 5 | Colony development and physiological characterization of the edible blue-green alga,Nostoc sphaeroides (Nostocaceae,Cyanophyta)显示文摘可食的蓝绿色的水藻, Nostoc sphaeroides K ü t 精力,能形成微殖民地和球形的宏殖民地。它被用作因为它的 nutraceutical 和药理学,草药的药和饮食的补充几个世纪有益于的一个有势力。然而,有限信息在球形的宏殖民地和影响他们的结构的环境因素的发展是可得到的。这份报告描述了 N 的形态发生。从单个毛状体的 sphaeroides 到宏殖民地。在这个过程期间,各种各样的尺寸的宏殖民地的很结构的特征是稠密的斑点,戒指,紧缩的核心和液体核心的形成;并且在宏殖民地以内的细丝显示出取决于宏殖民地的尺寸的不同长度和数组。同时,温度和轻紧张强烈也影响了宏殖民地的内部结构。同样微的殖民地进一步在尺寸增加了形成 30 个公里宏殖民地,区分进不同的外部、中间、内部的层的殖民地。外部层的细丝内部层比那些显示出更高最大的光合的率,更高轻的浸透点,和更高光合的效率;而内部层的细丝有叶绿素的一个更高的内容 and phycobiliproteins 比那些外部层。在这研究获得的结果为 N 的集体耕作是重要的。sphaeroides 作为一个 nutraceutical 产品。 | Zhongyang Deng Qiang Hu Fan Lu Guoxiang Liu Zhengyu Hu | 2008 | Progress in Natural Science:Materials International2008，18，12： | 7 |
| 6 | Geochemical Characteristics and Sources of Ore-forming Fluids of the Mayuan Pb-Zn Deposit,Nanzheng,Shaanxi,China显示文摘The Mayuan stratabound Pb-Zn deposit in Nanzheng,Shaanxi Province,is located in the northern margin of the Yangtze Plate,in the southern margin of the Beiba Arch.The orebodies are stratiform and hosted in breciated dolostone of the Sinian Dengying Formation.The ore minerals are primarily sphalerite and galena,and the gangue minerals comprise of dolomite,quartz,barite,calcite and solid bitumen.Fluid inclusions from ore-stage quartz and calcite have homogenization tempreatures from 98 to 337℃ and salinities from 7.7 wt%to 22.2 wt%(NaCl equiv.).The vapor phase of the inclusions is mainly composed of CH_4 with minor CO_2 and H_2S.The δD_(fluid) values of fluid inclusions in quartz and calcite display a range from-68‰ to-113‰(SMOW),and the δ^(18)O_(fluid)values calculated from δ^(18)O_(quartz) and δ^(18)O_(calcite) values range from 4.5‰ to 16.7‰(SMOW).These data suggest that the ore-forming fluids may have been derived from evaporitic sea water that had reacted with organic matter.The δ^(13)C_(CH4) values of CH_4 in fluid inclusions range from-37.2‰ to-21.0‰(PDB),suggesting that the CH_4 in the ore-forming fluids was mainly derived from organic matter.This,together with the abundance of solid bitumen in the ores,suggest that organic matter played an important role in mineralization,and that the thermochemical sulfate reduction(TSR) was the main mechanism of sulfide precipitation.The Mayuan Pb-Zn deposit is a carbonate-hosted epigenetic deposit that may be classified as a Mississippi Valley type(MVT) deposit. | LIU Shuwen LI Ronxi CHI Guoxiang ZENG Rong LIU Lingfang SHI Shun | 2015 | Acta Geologica Sinica(English Edition)2015，89，3： | 5 |
| 7 | Detecting land subsidence near metro lines in the Baoshan district of Shanghai with multi-temporal interferometric synthetic aperture radar显示文摘Land subsidence is a major factor that affects metro line(ML) stability. In this study, an improved multitemporal interferometric synthetic aperture radar(InSAR)(MTI) method to detect land subsidence near MLs is presented. In particular, our multi-temporal InSAR method provides surface subsidence measurements with high observation density. The MTI method tracks both point-like targets and distributed targets with temporal radar backscattering steadiness. First, subsidence rates at the point targets with low-amplitude dispersion index(ADI) values are extracted by applying a least-squared estimator on an optimized freely connected network. Second, to reduce error propagation, the pixels with high-ADI values are classified into several groups according to ADI intervals and processed using a Pearson correlation coefficient and hierarchical analysis strategy to obtain the distributed targets. Then,nonlinear subsidence components at all point-like and distributed targets are estimated using phase unwrapping and spatiotemporal filtering on the phase residuals. The proposed MTI method was applied to detect land subsidence near MLs of No. 1 and 3 in the Baoshan district of Shanghai using 18 TerraSAR-X images acquired between April 21,2008 and October 30, 2010. The results show that the mean subsidence rates of the stations distributed along the two MLs are-12.9 and-14.0 mm/year. Furthermore, three subsidence funnels near the MLs are discovered through the hierarchical analysis. The testing results demonstrate the satisfactory capacity of the proposed MTI method in providing detailed subsidence information near MLs. | Tao Li Guoxiang Liu Hui Lin Rui Zhang Hongguo Jia Bing Yu | 2014 | Journal of Modern Transportation2014，22，3： | 4 |
| 8 | Neuritin promotes angiogenesis through inhibition of DLL4/Notch signaling pathway显示文摘Neuritin is a member of the neurotrophic factor family,which plays an important role in the promotion and development of the nervous system.Neuritin is also involved in angiogenesis.Neuritin was recently found to be a negative regulatory factor of the Notch 1 signaling pathway.Notch signaling pathway is known as a regulatory pathway of angiogenesis.Thus,neuritin may play a role in angiogenesis through the Notch signaling pathway.In the present study,we investigated the expressions of neuritin and Notch signaling pathway factors in the pulmonary vascular tissue.The results showed that neuritin expression was increased in the paraneoplastic vascular tissue and decreased in the lung cancer vascular tissue.The neuritin expression was increased with the increase of vascular tissue density,and a negative correlation between neuritin expression and delta-like ligand 4(DLL4)was identified in vascular tissues of lung cancer.Overexpression of neuritin in human umbilical vein endothelial cells(HUVECs)inhibited the expressions of Notch signaling pathway-associated factors,including DLL4,NICD,and Hes-1,and promoted the migration and tubular formation of HUVECs.In conclusion,our results indicated that neuritin is involved in angiogenesis and may play a role in angiogenesis through the Notch signaling pathway.This study provides a theoretical basis for clinical anti-angiogenesis therapy. | Li Yang Xuhui Wang Jiawei Sun Chunyan Liu Guoxiang Li Jingling Zhu Jin Huang | 2021 | Acta Biochimica et Biophysica Sinica2021，53，6： | 4 |
| 9 | Monitoring subsidence rates along road network by persistent scatterer SAR interferometry with high-resolution TerraSAR-X imagery显示文摘Ground subsidence is one of the key factors damaging transportation facilities,e.g.,road networks consisting of highways and railways.In tiiis paper,we propose to apply the persistent scatterer synthetic aperture radar interferometry(PS-InSAR)approach mat uses highresolution TerraSAR-X(TSX)imagery to extract the regional scale subsidence rates(i.e.,average annual subsidence in mm/year)along road networks.The primary procedures involve interferometric pair selection,interferogram generation,persistent scatterer(PS)detection,PS networking,phase parameterization,and subsidence rate estimation.The Xiqing District in southwest Tianjin(China)is selected as the study area.This district contains one railway line and several highway lines.A total of 15TSX images covering this area between April 2009 and June 2010 are utilized to obtain the subsidence rates by using the PS-InSAR(PSI)approach.The subsidence rates derived from PSI range from—68.7 to—1.3 mm/year.These findings show a significantly uneven subsidence pattern along the road network.Comparison between the PSI-derived subsidence rates and the leveling data obtained along the highways shows that the mean and standard deviation(SD)of the discrepancies between die two types of subsidence rates are 0.1 and±3.2 mm/year,respectively.The results indicate that the high-resolution TSX PSI is capable of providing comprehensive and detailedsubsidence information regarding road networks with millimeter-level accuracy.Further inspections under geological conditions and land-use categories in the study area indicate that the observed subsidence is highly related to aquifer compression due to groundwater pumping.Therefore,measures should be taken to mitigate groundwater extraction for the study area. | Bing Yu Guoxiang Liu Rui Zhang Hongguo Jia Tao Li Xiaowen Wang Keren Dai Deying Ma | 2013 | Journal of Modern Transportation2013，21，4： | 4 |
| 10 | Circadian clock gene expression regulates cancer cell growth through glutaminase显示文摘夫酸安是为恶意的肿瘤房间的必要氨基酸。使夫酸安产生代射变化的 Glutaminase 到达肿瘤立即在最大的增长前评估的最大的 expressionin。肿瘤房间在日子期间以不同的率成长。我们 postulatedthat 在肿瘤房间的 glutaminase 的活动服从于生理节奏的钟基因的规定。我们测量了由在在六 equispaced 时间的肝和 tumorcells 的即时聚合酶链反应的西方的污点分析和生理节奏的钟基因表示削尖的 glutaminaseby 在一张 12/12 h 光 / 黑暗时间表的单个鼠标今日。结果显示出 thatthe 忍受肿瘤的鼠标,在正常下面日报条件,生理节奏地被乘火车,由正常主机 locomotoractivity 节奏和有韵律的肝钟基因表示思考了。在这些老鼠以内的肿瘤生理节奏地也被组织,由生理节奏的钟基因(Bmal1 ) 的 asreflected 表示。是很显著的的,是肾类型 glutaminase 也在一样的模式 withtumor 显示出生理节奏的节奏在肝癌症异种皮移植模型的生理节奏的钟基因表示,有条件地显示那禁止 glutaminaseactivity 可以为癌症提供一个新目标治疗。 | Aixia Huang Bingbo Bao H Rex Gaskins Haijun Liu Xueli Zhang Liwen Lu Shan Gao Yihai Shi Ming Zhang Yuanzhou Shan Jing Feng Guoxiang Yao | 2014 | Acta Biochimica et Biophysica Sinica2014，46，5： | 3 |
| 11 | Enhanced learning and memory in GAT1 heterozygous mice显示文摘-Aminobutyric 酸(伽马氨基丁酸) 是在中央神经系统的主要禁止的 neurotransmitter。伽马氨基丁酸传播的结束通过膜蛋白质的一个家庭的行动,叫的伽马氨基丁酸 transporters (GAT14 ) 。伽马氨基丁酸系统涉及存储器的调整,这很好被建立。我们的以前的学习显示出老鼠展出了损害马头鱼尾的怪兽依赖者学习和记忆的那同型结合的 GAT1/ 。在鼠标上评估内长的减少的伽马氨基丁酸举起的影响认知行为,学习和异质接合的 GAT1+/ 鼠标的存储器的能力被被动回避范例和莫利斯舞水迷宫检测。洞板范例也被用来在如此的老鼠在焦虑相关的行为或探索行为测量变化。作为 synaptic 粘性的一种形式,长期的 potentiation 在老鼠被记录海马趾的 CA1 区域。我们发现了显示的老鼠增加了的那 GAT1+/ 学习并且记忆,减少的像焦虑的行为,和与野类型、同型结合的 GAT1/ 老鼠相比的最高的 synaptic 粘性。我们的结果建议在 GAT1 活动的中等减小引起在鼠标学习和记忆的改进。 | Jun Shi Youqing Cai Guoxiang Liu Neng Gong Zhenze Liu Tianle Xu Zhugang Wang Jian Fei | 2012 | Acta Biochimica et Biophysica Sinica2012，44，4： | 3 |
| 12 | Characterization of the target DNA sequence for the DNA-binding domain of zinc finger protein 191显示文摘抄写因素的 DNA 有约束力的性质上的研究在寻找这些因素调整的下游的基因是重要的。在现在的学习,我们在一个 Cy s2His2 类型抄写因素的 DNA 有约束力的性质上报导,锌手指蛋白质 191 (Zfpl91 ) ,它最新被发现了在老鼠起一个重要作用。由构造包含 Zfpl91 的 DNA 有约束力的域的熔化蛋白质,我们由在锌上决定蛋白质的有约束力的特性和依赖描绘了目标 DNA。数据证明 Zfpl91 的 DNA 有约束力的域能明确地绑在 TCAT 重复主题并且在目标 DNA 的多重有约束力的地点之中有合作效果。而且,有约束力的反应依赖于锌。这个工作在基因规定和开发在 Zfpl91 的角色上为进一步的研究提供一个基础。 | Haoyue Wang Ruilin Sun Guoxiang Liu Minghui Yao Jian Fei Hebai Shen | 2008 | Acta Biochimica et Biophysica Sinica2008，40，8： | 3 |
| 13 | Aberrantly expressed GFRα-1/RET in patients with lacrimal adenoid cystic carcinoma is associated with high recurrence risk:a retrospective study of 51 LACC cases显示文摘Objective:Because of the poor prognosis of lacrimal adenoid cystic carcinoma(LACC),we aimed to investigate the effects of perineural invasion(PNI)and consequent aberrations in GDNF/GFRα-1/RET protein expression on LACC recurrence.Methods:Clinicopathological data for 51 histologically confirmed patients with LACC enrolled between 2001 and 2017 were retrospectively analyzed.Hematoxylin and eosin staining was applied to assess PNI.Tissue-based immunohistochemistry(IHC)detection of GDNF,GFRα-1,and RET proteins was performed on LACC formalin-fixed,paraffin-embedded specimens.We generated semi-quantitative data of the IHC results and compared them with the clinicopathological data for the 51 patients.Results:Of the 51 patients,19(37.3%)were PNI positive.Recurrence was more common for LACC with than without PNI(73.7%vs.37.5%,P=0.01).GDNF,GFRα-1,and RET proteins were expressed in 62.7%,62.7%,and 54.9%of the 51 patients with LACC,respectively.The expression of all 3 proteins was more common in patients with than without PNI.In agreement with previous findings,PNI-associated GFRα-1 and RET positivity,as detected by IHC,remained significantly associated with recurrence,whereas GDNF expression,as detected by IHC,was not correlated with LACC recurrence.Specifically,patients with concurrent GFRα-1 and RET expression may have a high risk of PNI(89.5%positivity rate)and recurrence(84.2%positivity rate).Conclusions:PNI may contribute to LACC recurrence.The concurrent expression of GFRα-1 and RET proteins,as detected by IHC,may potentially be associated with LACC PNI and recurrence. | Lin Liu Liqiong Zhao Jie Zhang Guoxiang Song Carol LShields Ruihua Wei | 2021 | Cancer Biology & Medicine2021，18，1： | 3 |
| 14 | Improved method to raise polyclonal antibody using enhanced green fluorescent protein transgenic mice显示文摘Recombinant 熔化蛋白质广泛地被用作抗原对目标蛋白质的 epitope 提起抗体。然而,在产生抗血清的伴随物反搬运人抗体减少需要的抗体的生产并且引起讨厌的非特定的有免疫力的反应。这被建议搬运人蛋白质转基因的动物能被用来解决这个问题。验证这个假设,提高的绿荧光灯的蛋白质(EGFP ) 转基因的老鼠被生产。由与熔化蛋白质 His6HAtag-EGFP 使老鼠免疫,我们证明从转基因的老鼠的抗血清从野类型的老鼠与那相比对 EGFP 对 His6HA 标签和更低的 titer 抗体有更高的 titer 抗体。因此,这份报告描述一个改进方法用能在抗体准备有申请潜力的 EGFP 转基因的老鼠提起高 titer 反肽 polyclonal 抗体。 | Jianke Ren Long Wang Guoxiang Liu Wen Zhang Zhejin Sheng Zhugang Wang Jian Fei | 2008 | Acta Biochimica et Biophysica Sinica2008，40，2： | 3 |
| 15 | Extraction and analysis of saline soil deformation in the Qarhan Salt Lake region (in Qinghai, China) by the sentinel SBAS-InSAR technique显示文摘The instability of saline soil foundation affects the safety of artificial construction,and may cause ground collapse,building destruction and road damage.It is fundamental to reduce the potential engineering geological disasters by exploring the dynamic evolution of saline soil.Most of the previous researches of saline soil were conducted by simulated experiments and traditional geodetic surveying methods.Restricted to the limited sampling points,the spatiotemporal evolution characteristics of saline soil were difficult to find out in a large scale.This paper exploited SBAS-InSAR method to extract the deformation of the Qarhan Salt Lake(in Qinghai,China)section along Qinghai-Tibet railway,based on 119 image data acquired by Sentinel-1A from 2015 to 2020.The results showed that the deformation trends varied frequently in this saline mud flat.Between the adjacent areas with different deformation trends along Qinghai-Tibet railway,discontinuities caused by uplift and subsidence were very obvious.Besides,among the areas with brine exploitation or artificial construction,the maximum subsidence rate reached50 mm/yr,and the maximum cumulative subsidence exceeded 320 mm in the latest 5 years.In the saline mud flat closed to the rivers and lakes,the deformation trend was continuous uplift.Nevertheless,there were obvious seasonal deformation characteristics in those areas far away from the water body.Further analysis found out a sharply subsidence caused by the salt collapsibility appeared in rainy seasons.While an uplift trend induced by the salt swelling or frost heave was remarkable in dry seasons.Subsequently,the relationships were analyzed between the time series deformation and external environmental fac-tors.Furthermore,the deformation mechanism of saline soilin the Qarhan Salt Lake region was inter-preted then.In general,this study provides complete spatiotemporal evolution information of saline soil,and demonstrates the deformation characteristics of saline soil in the Qarhan Salt Lake region suc-cessfully.Related results would contribute to the safety monitoring for large-scale infrastructure con-struction in the saline soil areas. | Wei Xiang Rui Zhang Guoxiang Liu Xiaowen Wang Wenfei Mao Bo Zhang Jialun Cai Jiawen Bao Yin Fu | 2022 | Geodesy and Geodynamics2022，13，2： | 2 |
| 16 | Consensus control and feedback graph co-design for MIMO discrete-time multi-agent systems显示文摘This paper studies consensus control for multi-input/multi-output(MIMO)discrete-time multi-agent systems(MASs).It makes use of the novel idea of resource allocation in designing both the communication graph and feedback controller.The weakest consensusability condition is obtained for MASs over both directed and undirected graphs,which extends the existing results to MIMO discrete-time MASs.Explicit synthesis procedures are also developed.Our work demonstrates the importance of the graph and controller co-design based on resource allocation for MIMO discrete-time MASs. | Guoxiang Gu Fei Liu Xiang Chen | 2014 | Journal of Control and Decision2014，1，1： | 2 |
| 17 | TiC/C core/shell nanowires arrays as advanced anode of sodium ion batteries显示文摘High-perfo rmance anodes of sodium ion batteries(SIBs)largely depends on rational architecture design and binder-free smart hybridization.Herein,we report TiC/C core/shell nanowires arrays prepared by a one-step chemical vapor deposition(CVD)method and apply it as the anode of SIBs for the first time.The conductive TiC core is intimately decorated with carbon shell.The as-obtained TiC/C nanowires are homogeneously grown on the substrate and show core/shell heterostructure and porous architecture with high electronic conductivity and reinforced stability.Owing to these merits,the TiC/C electrode displays good rate performance and outstanding cycling performance with a capacity of 135.3 mAh/g at 0.1 A/g and superior capacity retention of 90.14%after 1000 cycles at 2 A/g.The reported strategy would provide a promising way to construct binder-free arrays electrodes for sodium ion storage. | Yanbin Shen Yahao Li Shengjue Deng Guoxiang Pan Qinqin Xiong Xiaokun Ding Yangfan Lu Qi Liu Xinhui Xia Xiuli Wang Jiangping Tu | 2020 | Chinese Chemical Letters2020，31，3： | 2 |
| 18 | Self-supported hierarchical porous Li_(4)Ti_(5)O_(12)/carbon arrays for boosted lithium ion storage显示文摘The development of fast rechargeable lithium ion batteries(LIBs)is highly dependent on the innovation of advanced high-power electrode materials.In this work,for the first time,we report a sacrificial NiO arrays template method for controllable synthesis of self-supported hierarchical porous Li_(4)Ti_(5)O_(12)/C(LTO/C)nanoflakes arrays,for use as fast rechargeable anodes for LIBs.The ultrathin(2-3 nm)carbon layer was uniformly coated on the LTO forming arrays architecture.The hierarchical porous LTO/C nanoflakes consisted of primary cross-linked nanoparticles of 50-100 nm and showed large porosity.Because of the enhanced electrical conductivity and accelerated ion transfer channels,the well-designed binderfree porous LTO/C nanoflakes arrays exhibited notable high-rate lithium ion storage performance with smaller polarization,better electrochemical reactivity,higher specific capacity(157 mAh g^(-1) at the current density of 20C)and improved long-term cycling life(96.2% after 6000 cycles at 20C),superior to the unmodified porous LTO arrays counterpart(126 mAh g^(-1) at 20C and 88.0%after 6000 cycles at 20C).Our work provides a new template for the construction of high-performance high-rate electrodes for electrochemical energy storage. | Jun Liu Aixiang Wei Guoxiang Pan Shenghui Shen Zhiming Xiao Yu Zhao Xinhui Xia | 2021 | Journal of Energy Chemistry2021，30，3： | 2 |
| 19 | Frequent RNF43 mutation contributes to moderate activation of Wnt signaling in colorectal signet-ring cell carcinoma显示文摘Dear Editor,Signet-ring cell carcinoma(SRCC)is a rare subtype of colorectal cancer(CRC)characterized histologically by the accumulation of mucins in the cytoplasm and displacement of nuclei to the cellular periphery,accounting for about 1%CRC(Fig.S1A)(Borger et al.,2007).Compare to common subtypes of CRC,such as adenocarcinoma(AC)and mucinous adenocarcinoma(MAC),SRCC is associated with aggressive behaviors and younger age at presentation(Kang et al.,2005;Sung et al.,2008;Nitsche et al.,2013;Hugen et al.,2014;Inamura et al.,2015).A retrospective analysis of CRC patient's data at Fudan University Shanghai Cancer Center(FUSCC)also indicated a worse overall and disease-free survival of SRCC patients(Fig.S1B and S1C,Table S1). | Yaqi Li Jian Li Renjie Wang Long Zhang Guoxiang Fu Xueying Wang Yebin Wang Chuantao Fang Dandan Zhang Duo Du Xiaoji Ma Mengxue Pan Qiang Guo Xiaoya Xu Xiang Hu Yi Zhou Shaobo Mo Huijun Wang Jianjun Gao Shenglin Huang Yun Liu Sanjun Cai Guoqiang Hua Junjie Peng Fa-Xing Yu | 2020 | Protein & Cell2020，11，4： | 2 |
| 20 | E3 ligase FBXW7 aggravates TMPD-induced systemic lupus erythematosus by promoting cell apoptosis显示文摘Systemic lupus erythematosus(SLE)is a systemic autoimmune disease,and the pathogenesis of SLE has not been fully elucidated.The E3 ubiquitin ligase FBXW7 has been well characterized in cancer as a tumor suppressor that can promote the ubiquitination and subsequent degradation of various oncoproteins;however,the potential role of FBXW7 in autoimmune diseases is unclear.In the present study,we identified that FBXW7 is a crucial exacerbating factor for SLE development and progression in a mouse model induced by 2,6,10,14-tetramethylpentadecane(TMPD).Myeloid cell-specific FBXW7-deficient(Lysm+FBXW7f/f)C57BL/6 mice showed decreased immune complex accumulation,glomerulonephritis,glomerular mesangial cell proliferation,and basemembrane thickness in the kidney.Lysm+FBXW7f/f mice produced fewer anti-Sm/RNP and anti-ANA autoantibodies and showed a decreased MHC II expression in B cells.In Lysm+FBXW7f/f mice,we observed that cell apoptosis was reduced and that fewer CD11b+Ly6Chi inflammatory monocytes were recruited to the peritoneal cavity.Consistently,diffuse pulmonary hemorrhage(DPH)was also decreased in Lysm+FBXW7f/f mice.Mechanistically,we clarified that FBXW7 promoted TMPD-induced cell apoptosis by catalyzing MCL1 degradation through K48-linked ubiquitination.Our work revealed that FBXW7 expression in myeloid cells played a crucial role in TMPD-induced SLE progression in mice,which may provide novel ideas and theoretical support for understanding the pathogenesis of SLE. | Zhenlu Chong Chunjing Bao Jia He Tianxiao Chen Lijia Zhong Gaopeng Li Huanle Li Lutong Fang Yinjing Song Guoxiang Fu Xuyan Yang Lihua Lai Yang Liu Qingqing Wang | 2018 | Cellular & Molecular Immunology2018，15，12： | 2 |
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