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| 1 | 自发性脑出血治疗指南美国心脏协会/美国卒中协会对医疗卫生专业人员发布的指南显示文摘目的本指南旨在为急性自发性脑出血的诊断和治疗提供最新的综合性推荐意见。方法通过Medline进行规范的文献检索,利用证据表合并资料。撰写委员会成员通过远程电信会议讨论根据资料得出的推荐意见。采用美国心脏协会卒中委员会的证据分级方案对推荐意见进行分级。由6位同行评议专家以及卒中委员会科学声明监督委员会和卒中委员会领导委员会成员对指南的草案进行发表前审阅。预期本指南在3年内完全更新。结果本文为脑出血患者的医疗诊治提供了循证指南。重点包括诊断、止血、血压管理、院内管理和护理、预防内科合并症、外科治疗、转归预测、康复、预防复发以及将来需要考虑的问题。结论脑出血是一种严重的疾病,早期积极救治可影响其转归。本指南为脑出血患者的目标导向治疗提供了一个框架。 | Lewis B. Morgenstem J. Claude Hemphill Ⅲ Craig Anderson Kyra Becker Joseph P. Broderick E. Sander Connolly Jr Steven M. Greenberg James N. Huang R. Loch Macdonald Steven R. Messe Pamela H. Mitchell Magdy Selim Rafael J. Tamargo 王玉洁(译) 王健(译) 刘相玉(译) 谢丽丽(译) | 2010 | 国际脑血管病杂志2010，，8： | 259 |
| 2 | Guidelines for the Management of Spontaneous Intracerebral Hemorrhage: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association显示文摘 | Lewis B. Morgenstern J. Claude Hemphill Craig Anderson Kyra Becker Joseph P. Broderick E. Sander Connolly Steven M. Greenberg James N. Huang R. Loch Macdonald Steven R. Messé Pamela H. Mitchell Magdy Selim Rafael J. Tamargo | 2010 | Stroke2010，，9： | 10 |
| 3 | 美国肺动脉高压治疗指南显示文摘 | David B.Badesch Steven H.Abman Gerald Simonneau Lewis J.Rubin Vallerie V.McLaughlin 李井泉 | 2008 | 中国全科医学2008，11，2： | 7 |
| 4 | Mycophenolate mofetil for maintenance of remission in steroid-dependent autoimmune pancreatitis显示文摘Systemic corticosteroids represent the standard treatment for autoimmune pancreatitis with IgG4-associated cholangitis.For steroid-dependent disease,azathioprine has been used for maintenance of remission.Mycophenolate mofetil has been used for transplant immunosuppression and more recently for autoimmune hepatitis;however,there are no case reports to date on the use of mycophenolate mofetil in adult patients with autoimmune pancreatitis.A patient with IgG4-mediated autoimmune pancreatitis and IgG4-associated cholangitis refractory to steroids and intolerant of azathioprine was treated with mycophenolate mofetil,which inhibits de novo guanosine synthesis and blockade of both B and T lymphocyte production.Introduction of mycophenolate mofetil and uptitration to 1000 mg by mouth twice daily over a treatment period of 4 mo was associated with improvement in the patient's energy level and blood glucose control and was not associated with any adverse events.The patient was managed without a biliary stent.However,there was a return of symptoms,jaundice,increase in transaminases,and hyperbilirubinemia when the prednisone dose reached 11 mg per day.In the first report of mycophenolate mofetil use in an adult patient with IgG4-associated autoimmune pancreatitis and IgG4-associated cholangitis,the introduction of mycophenolate mofetil was safe and well-tolerated without adverse events,but it did not enable discontinuation of the steroids.Mycophenolate mofetil and other immunomodulatory therapies should continue to be studied for maintenance of remission in the large subset of patients with refractory or recurrent autoimmune pancreatitis. | Jamie B Sodikoff Steven A Keilin Sheila J Bharmal Melinda M Lewis Gottumukkala S Raju Field F Willingham | 2012 | World Journal of Gastroenterology2012，18，18： | 6 |
| 5 | PrP^C-related signal transduction is influenced by copper, membrane integrity and the alpha cleavage site显示文摘铜绑定,抛锚膜的、细胞的 prion 蛋白质(PrPC ) 有二个组成的劈开地点生产不同 N 终端和 C 终端碎片(N1/C1 和 N2/C2 ) 。用表示也人的 PrPC,鼠标 PrPC 或鼠标 PrPC 的 RK13 房间带 3F4 epitope,这研究在 endoproteolytic 劈开和一个通常认为的 PrPC 函数上探索了 PrPC 主要顺序的影响,地图 kinase 信号 transduction,响应外长的铜与或没有使不安的膜环境。PrPC 主要顺序,特别在 N1/C1 劈开地点附近,看起来在这个地点和细胞外的调整信号的 kinase 1/2 (ERK1/2 ) phosphorylation 影响解朊作用的基础层次,与处理激活增加与基础 ERK1/2 表明一种反的关系。人的 PrPC 独自响应铜显示出增加的 N1/C1 劈开,由特定的 p38 和 JNK/SAPK phosphorylation 伴随了。到加扣押胆固醇的抗菌素 filipin 的铜的联合暴露导致了一只老鼠信号蛋白质 phosphorylation 的 PrPC 特定的实质的增加,由 N1/C1 劈开的增加伴随了。怀有人的 N1/C1 劈开地点的老鼠 PrPC 基础地并且响应铜假定更似人类的侧面并且改变了膜环境。我们的结果证明在 N1/C1 劈开地点附近的 PrPC 主要顺序影响在这个地点处理的 endoproteolytic,它显得连接了基础地并且响应铜印射 kinase 信号 transduction。进一步,主要顺序看起来响应外长的刺激在 PrPC 相关的信号 transduction 的忠实上授与 N1/C1 劈开和膜完整的相互的依赖。 | Cathryn L Haigh | 2009 | Cell Research2009，19，9： | 4 |
| 6 | 2009 Canadian Cardiovascular Society/Canadian guidelines for the diagnosis and treatment of dyslipidemia and prevention of cardiovascular disease in the adult – 2009 recommendations显示文摘 | Jacques Genest Ruth McPherson Jiri Frohlich Todd Anderson Norm Campbell André Carpentier Patrick Couture Robert Dufour George Fodor Gordon A. Francis Steven Grover Milan Gupta Robert A. Hegele David C. Lau Lawrence Leiter Gary F. Lewis Eva Lonn G.B. John | 2009 | Canadian Journal of Cardiology2009，，10： | 2 |
| 7 | Automatic classification of Web queries using very large unlabeled query logs显示文摘 | Steven M Jensen E C Lewis D D | 2007 | ACM Transaction on Information Systems (TOIS)2007，25，2： | 1 |
| 8 | Interpretation of metal concentrations in estuarine sediments of Florida using aluminum as a reference element显示文摘 | Steven J. Schropp F. Graham Lewis Herbert L. Windom Joe D. Ryan Fred D. Calder Louis C. Burney | 1990 | Estuaries1990，，3： | 1 |
| 9 | Visibility and aerosol composition in Houston,Texas显示文摘 | Dzubay T G Stevens R K Lewis C W | 1982 | Environ Sci Technol1982，16，8： | 1 |
| 10 | Lipid profiling identifies a triacylglycerol signature of insulin resistance and improves diabetes prediction in humans显示文摘 | Rhee Eugene P Cheng Susan Larson Martin G Walford Geoffrey A Lewis Gregory D McCabe Elizabeth Yang Elaine Farrell Laurie Fox Caroline S O’Donnell Christopher J Carr Steven A Vasan Ramachandran S Florez Jose C Clish Clary B Wang Thomas J Ger | 2011 | Journal of Clinical Investigation2011，，4： | 1 |
| 11 | How early is early laparoscopic treatment of acute cholecystitis?显示文摘 | Atul K Madan Shaghayegh Aliabadi-Wahle Donna Tesi Lewis M Flint Steven M Steinberg | 2002 | The American Journal of Surgery2002，，3： | 1 |
| 12 | Aerosol properties over bright-reflecting source region显示文摘 | Dzubay T G Stevens R K Lewis C W | 2004 | IEEE Transactions on Geoscience and Remote Sensing2004，42，3： | 1 |
| 13 | Egg white proteins 显示文摘 | Lewis Stevens | 1991 | Comp Biochem Physical1991，100，1： | 1 |
| 14 | Interleukin-1activates phospholipase A2 in rabbit chondrocytes: A possible signal for IL-1 action显示文摘 | Joseph Chang Steven C Gilman and Alan J Lewis | 1986 | Journal of Immuology1986，136，： | 1 |
| 15 | Feasibility and Predictability of Perioperative PET and Estrogen Receptor Ligand in Patients with Invasive Breast Cancer显示文摘 | Mary L. Gemignani Sujata Patil Venkatraman E. Seshan Michelle Sampson John L. Humm Jason S. Lewis Edi Brogi Steven M. Larson Monica Morrow Neeta Pandit-Taskar | 2013 | Journal of Nuclear Medicine2013，，10： | 1 |
| 16 | Effects of Aspirin Dose When Used Alone or in Combination With Clopidogrel in Patients With Acute Coronary Syndromes: Observations From the Clopidogrel in Unstable angina to prevent Recurrent Events (CURE) Study显示文摘 | Ron J.G. Peters Shamir R. Mehta Keith A.A. Fox Feng Zhao Basil S. Lewis Steven L. Kopecky Rafael Diaz Patrick J. Commerford Vicent Valentin Salim Yusuf | 2003 | Circulation: Journal of the American Heart Association2003，，14： | 1 |
| 17 | Fate of Biotinylated Basic Fibroblast Growth Factor in the Retina Following Intravitreal Injection显示文摘 | GEOFFREY P. LEWIS STEVEN K. FISHER DON H. ANDERSON | 1996 | Experimental Eye Research1996，，3： | 1 |
| 18 | Negative state weighting in the linear quadratic regulator for aircraft control 显示文摘 | Al-SUMNI F M STEVENS B L LEWIS F L | 1992 | J of Guidance Control and Dynamics1992，15，5： | 1 |
| 19 | Differences in shame and pride as a function of children' s gender and task difficulty 显示文摘 | Lewis M Alessandri Steven M Sullivan M W | 1992 | Child Development1992，63，3： | 1 |
| 20 | Isolation and Characterization of Circulating Tumor Cells in Patients with Metastatic Colorectal Cancer显示文摘 | Steven J. Cohen R. Katherine Alpaugh Steve Gross Shawn M. O’Hara Denis A. Smirnov Leon W.M.M. Terstappen W. Jeffrey Allard Maryann Bilbee Jonathan D. Cheng John P. Hoffman Nancy L. Lewis Ann Pellegrino André Rogatko Elin Sigurdson Hao Wang James C. Watson | 2006 | Clinical Colorectal Cancer2006，，2： | 1 |
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