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| 1 | Crystal structure of HLA-B*5801, a protective HLA allele for HIV-1 infection显示文摘 | Xiaolong Li Pedro A. Lamothe Robert Ng Shutong Xu Maikun Teng Bruce D. Walker Jia-huai wang | 2016 | Protein & Cell2016，7，10： | 2 |
| 2 | A Preliminary Investigation of Arctic Sea Ice Negative Freeboard from in-situ Observations and Radar Altimetry显示文摘The negative freeboard of sea ice(i.e., the height of ice surface below sea level) with subsequent flooding is widespread in the Southern Ocean, as opposed to the Arctic, due to the relatively thicker ice and thinner snow. In this study, we used the observations of snow and ice thickness from 103 ice mass balance buoys(IMBs) and NASA Operation IceBridge Aircraft Missions to investigate the spatial distribution of negative freeboard of Arctic sea ice. The Result showed that seven IMBs recorded negative freeboards, which were sporadically located in the seas around Northeast Greenland, the Central Arctic Ocean, and the marginal areas of the Chukchi–Beaufort Sea. The observed maximum values of negative freeboard could reach-0.12 m in the seas around Northeast Greenland. The observations from IceBridge campaigns also revealed negative freeboard comparable to those of IMBs in the seas around North Greenland and the Beaufort Sea. We further investigated the large-scale distribution of negative freeboard using NASA CryoSat-2 radar altimeter data, and the result indicates that except for the negative freeboard areas observed by IMBs and IceBridge, there are negative freeboards in other marginal seas of the Arctic Ocean. However, the comparison of the satellite data with the IMB data and IceBridge data shows that the Cryosat-2 data generally overestimate the extent and magnitude of the negative freeboard in the Arctic. | LI Shutong DOU Tingfeng XIAO Cunde | 2021 | Journal of Ocean University of China2021，20，2： | 2 |
| 3 | Unimodal productivity-biodiversity relationship along the gradient of multidimensional resources across Chinese grasslands显示文摘Resources can affect plant productivity and biodiversity simultaneously and thus are key drivers of their relationships in addition to plant-plant interactions.However,most previous studies only focused on a single resource while negle cting the nature of resource multidimensionality.Here we integrated four essential resources for plant growth into a single metric of resource diversity(RD)to investigate its effects on the productivity-biodiversity relationship(PBR)across Chinese grasslands.Results showed that habitats differing in RD have different PBRs—positive in low-resource habitats,but neutral in medium-and high-resource ones—while collectively,a weak positive PBR was observe d.However,when excluding direct effects of RD on productivity and biodiversity,the PBR in high-resource habitats became negative,which leads to a unimodal instead of a positive PBR along the RD gradient.By integrating resource effects and changing plant-plant interactions into a unified framework with the RD gradient,our work contributes to uncovering underlying me chanisms for inconsistent PBRs at large scales. | Yanfen Wang Jianqing Du Zhe Pang Yali Liu Kai Xue Yann Hautier Biao Zhang Li Tang Lili Jiang Baoming Ji Xingliang Xu Jing Zhang Ronghai Hu Shutong Zhou Fang Wang Rongxiao Che Di Wang Chaoting Zhou Xiaoyong Cui Nico Eisenhauer Yanbin Hao | 2022 | National Science Review2022，9，12： | 2 |
| 4 | Crystal structures of isoorotate decarboxylases reveal a novel catalytic mechanism of 5-carboxyl-uracil decarboxylation and shed light on the search for DNA decarboxylase显示文摘DNA methylation 和 demethylation 在哺乳动物调整许多关键生物过程并且被连接到许多疾病。活跃 DNA demethylation 被相信被 TET 蛋白质和可以与在真菌催化 5caU 的去碳酸基到 U 的 isoorotate decarboxylase (IDCase ) 在顺序,结构和催化机制分享一些类似的通常认为的 DNA decarboxylase 催化。我们这里与 5caU, U,和禁止者 5-nitro-uracil 在 apo 形式或在建筑群从 Cordyceps militaris 和 Metarhizium anisopliae 报导野类型、变异的 IDCases 的结构。IDCases 采用一典型(β /α) amidohydrolase 总科和功能的 8 桶褶层作为 dimers。Zn 2+ 在活跃地点被绑并且由四严格地保存的残余协调了,一条毒蛇并且三他的。底层被几严格地保存的残余认出。在活跃地点的关键残余的功能的角色被 mutagenesis 和生物化学的研究验证。基于结构、生物化学的数据,我们在场第一次为 IDCases 的去碳酸基的新奇催化机制,它可能也适用于 amidohydrolase 总科的另外的成员。另外,我们 IDCases 能催化的生物化学的数据表演到有弱活动的 C 虽然的 5caC 的去碳酸基,它在为到由酶的 C 的 5caC 的直接去碳酸基的 vitro 证据是第一。这些调查结果在在哺乳动物的潜在的 DNA decarboxylase 的鉴定是珍贵的。 | Shutong Xu Wenjing Li Junjun Zhu Rong Wang Zheng Li Guo-Liang Xu Jianping Ding | 2013 | Cell Research2013，23，11： | 1 |
| 5 | Effects of retrograde-zoning of garnet on Sm-Nd isotopic dating of eclogite and oxygen isotopic disequilibrium between eclogitic minerals显示文摘 | Shuguang Li Liu Yican Shutong Xu Yongfei Zheng | 2002 | Science in China Series B: Chemistry2002，，1： | 1 |
| 6 | Dual pH‐ and temperature‐responsive hydrogels with extraordinary swelling/deswelling behavior and enhanced mechanical performances显示文摘 | Shutong Huang Jianfeng Shen Na Li Mingxin Ye | 2015 | J. Appl. Polym. Sci2015，，9： | 1 |
| 7 | A HEVC Video Steganalysis Algorithm Based on PU Partition Modes显示文摘Steganalysis is a technique used for detecting the existence of secret information embedded into cover media such as images and videos.Currently,with the higher speed of the Internet,videos have become a kind of main methods for transferring information.The latest video coding standard High Efficiency Video Coding(HEVC)shows better coding performance compared with the H.264/AVC standard published in the previous time.Therefore,since the HEVC was published,HEVC videos have been widely used as carriers of hidden information.In this paper,a steganalysis algorithm is proposed to detect the latest HEVC video steganography method which is based on the modification of Prediction Units(PU)partition modes.To detect the embedded data,All the PU partition modes are extracted from P pictures,and the probability of each PU partition mode in cover videos and stego videos is adopted as the classification feature.Furthermore,feature optimization is applied,that the 25-dimensional steganalysis feature has been reduced to the 3-dimensional feature.Then the Support Vector Machine(SVM)is used to identify stego videos.It is demonstrated in experimental results that the proposed steganalysis algorithm can effectively detect the stego videos,and much higher classification accuracy has been achieved compared with state-of-the-art work. | Zhonghao Li Laijing Meng Shutong Xu Zhaohong Li Yunqing Shi Yuanchang Liang | 2019 | Computers, Materials & Continua2019，，5： | 1 |
| 8 | Hydrother real carbonization synthesis of a novel montmorillonite supported carbon nanosphere adsorbent for removal of Cr (VI) from waste water显示文摘 | Tie Li Jianfeng Shen Shutong Huang | 2014 | Applied Clay Science2014，93，5： | 1 |
| 9 | Precursor Based on Polyborylborazine for BN Fiber: Preparation and Rheology Properties显示文摘 | Shutong Li Yimiao Cao Keqing Han Xi Zhao Muhuo Yu | 2009 | Journal of Macromolecular Science, Part B2009，，： | 1 |
| 10 | The Saemaul Undong in Ko- rea Social Practice Based on the as the Peasant Interviewing Li Shuishan, the director of Compara- tive Education Research Centre of Central Institute of Educational of Ministry of Education显示文摘 | Li shutong | 2006 | Forum Rakyat2006，04，： | 1 |
| 11 | A mutation in the promoter of the yellow stripe-like transporter gene in cucumber results in a yellow cotyledon phenotype显示文摘Leaf color mutants in higher plants are considered to be ideal materials for studying the chlorophyll biosynthesis,photosynthesis mechanism and chloroplast development.Herein,we identified a spontaneous mutant,yc412,in cultivated cucumber that exhibited yellow cotyledons.The yellow-lethal mutant was diagnosed with an abnormal chloroplast ultrastructure,and reduced photosynthetic capacity and pigment content.Through bulked segregant analysis-based whole-genome sequencing and fine genetic mapping,we narrowed the yellow cotyledons (yc) locus to a 96.8 kb interval on chromosome 3.By resequencing and molecular cloning,we showed that Csyc is a potential candidate gene,which encodes a yellow stripe-like (YSL) transporter.The T to C mutation in the promoter region of Csyc caused the yellow cotyledon phenotype in yc412.Compared to YZU027A (WT),the expression of Csyc was significantly downregulated in the cotyledons of yc412.Silencing of Csyc in cucumber via virus-induced gene silencing resulted in chlorotic leaves,mainly by suppressing the chlorophyll content.Furthermore,a comparative transcriptome analysis revealed that chloroplast-related genes and chlorophyll biosynthesis genes were significantly downregulated in yc412 cotyledons.Our results provide new insights into the molecular function of the YSL transporter in plant chloroplast development and chlorophyll synthesis. | Jiawei Pan Jia Song Rahat Sharif Xuewen Xu Shutong Li Xuehao Chen | 2024 | Journal of Integrative Agriculture2024，23，3： | 0 |
| 12 | Suppressing the ferroelectric switching barrier in hybrid improper ferroelectrics显示文摘Integration of ferroelectric materials into novel technological applications requires low coercive field materials,and consequently,design strategies to reduce the ferroelectric switching barriers.In this first principles study,we show that biaxial strain,which has a strong effect on the ferroelectric ground states,can also be used to tune the switching barrier of hybrid improper ferroelectric Ruddlesden–Popper oxides.We identify the region of the strain-tolerance factor phase diagram where this intrinsic barrier is suppressed,and show that it can be explained in relation to strain-induced phase transitions to nonpolar phases. | Shutong Li Turan Birol | 2020 | npj Computational Materials2020，，1： | 0 |
| 13 | An observational study of precipitation types in the Alaskan Arctic显示文摘The effects of various precipitation types,such as snow,rain,sleet,hail and freezing rain,on regional hydrology,ecology,snow and ice surfaces differ significantly.Due to limited observations,however,few studies into precipitation types have been conducted in the Arctic.Based on the high-resolution precipitation records from an OTT Parsivel^(2) disdrometer in Utqiaġvik,Alaska,this study analysed variations in precipitation types in the Alaskan Arctic from 15 May to 16 October,2019.Results show that rain and snow were the dominant precipitation types during the measurement period,accounting for 92%of the total precipitation.In addition,freezing rain,sleet,and hail were also observed(2,4 and 11 times,respectively),accounting for the rest part of the total precipitation.The records from a neighbouring U.S.Climate Reference Network(USCRN)station equipped with T-200B rain gauges support the results of disdrometer.Further analysis revealed that Global Precipitation Measurement(GPM)satellite data could well characterise the observed precipitation changes in Utqiaġvik.Combined with satellite data and station observations,the spatiotemporal variations in precipitation were verified in various reanalysis datasets,and the results indicated that ECMWF Reanalysis v5(ERA5)could better describe the observed precipitation time series in Utqiaġvik and the spatial distribution of data in the Alaskan Arctic.Modern-Era Retrospective analysis for Research and Applications,Version 2(MERRA-2)overestimated the amount and frequency of precipitation.Japanese 55-year Reanalysis(JRA-55)could better simulate heavy precipitation events and the spatial distribution of the precipitation phase,but it overestimated summer snowfall. | YUE Handong DOU Tingfeng LI Shutong LI Chuanjin DING Minghu XIAO Cunde | 2021 | Advances in Polar Science2021，32，4： | 0 |
| 14 | Exploring the potential mechanism of Huanglian Jiedu Decoction against sepsis based on network pharmacology显示文摘Background Huanglian Jiedu Decoction(HJD) is a typical traditional Chinese medicine which exhibits diverse curative effects against different kinds of diseases because of its multi-components and multi-targets. It has been widely used for the treatment of sepsis. However, the underlying molecular mechanism is still unclear.Methods Network pharmacology was applied to analyze the potential active ingredients and molecular mechanism of HJD in the treatment of sepsis.Results As a result, we totally found 102 active ingredients and 221 corresponding targets. Among them, 117 were hit by the 1 837 targets associated with sepsis. Our further analysis demonstrated 57 drug and disease intersection targets. Based on Gene Ontology(GO) enrichment analysis, 2176 biological process terms, 84 molecular function terms and 28 cellular component terms were acquired. By performing Kyoto Encyclopedia of Genes and Genomes(KEGG) enrichment analysis, we acquired the dominating signaling pathways associated with sepsis. By constructing protein-protein interaction network of common targets, 11 hub genes were identified.Conclusions Taken together, our results indicated that HJD may protect against sepsis via a mechanism involving multiple targets and pathways. | Liu Yarong Li Shutong Jiang Yu Zou Lianhong Cheng Ting Liu Yanjuan | 2022 | 实用休克杂志(中英文)2022，6，2： | 0 |
| 15 | Conformation Changes of Enkephalin in Coordination with Pb^(2+) Investigated by Gas Phase Hydrogen/Deuterium Exchange Mass Spectrometry Combined with Theoretical Calculations显示文摘In this study, the effects of lead ions(Pb^(2+)) on the conformations of leucine encephalin(LE) and methionine encephalin(ME) in gas phase were studied using hydrogen/deuterium exchange mass spectrometry(HDX-MS) and quantum chemistry theoretical calculations at the molecular level. The HDX-MS result revealed that the complexes with the monovalent compounds [LE+Pb–H]+ and [ME+Pb–H]+had a 1:1 stoichiometric ratio, and different HDX reactivates were observed in a follow of [ME+H]+>[LE+H]+>[LE+Pb–H]+> [ME+Pb–H]+. Combining the collision-induced dissociation energies of the complexes and their HDX results, it was found that the more stable the complex, the harder it was for HDX. In addition, the favo-rable conformations of the complexes were obtained by theoretical calculations, revealing that the similar coordination type with diffe-rent bond lengths was obtained. Then, the proton affinity(PA) values of the optimized complexes were calculated to interpret the HDX observations, indicating that the higher the PA values, the more difficult it was for HDX. Overall, the experiments and theoretical calculations revealed that Pb^(2+) could induce conformational changes of LE and ME, and generate ME into a more rigid conformation than LE. The results will prompt further fundamental investigations on the conformational properties of LE/ME in coordination with Pb^(2+). | HAN Jiaru WU Fangling YANG Shutong WU Xiaonan TANG Keqi LI Zhenhua DING Chuan-Fan | 2022 | Chemical Research in Chinese Universities2022，38，2： | 0 |
| 16 | Build in seconds:Small-molecule hydrogels of self-assembled tryptophan derivatives显示文摘Small-molecule hydrogels based on amino acid derivatives have promising applications in many biological fields,including cell culture,drug delivery,and tissue engineering.Although these hydrogels have been widely reported to have low cytotoxicity,biocompatibility,and tunable bioactivity,problems such as harsh preparation conditions and complex material design hinder their application.Herein,by adjusting pH to induce non-covalent interactions between small-molecule tryptophan derivatives(N-[(phenylmethoxy)carbonyl]-L-tryptophan,Mw:338.35),we developed a self-assembled three-dimensional network hydrogel that can be rapidly formed in seconds.And the supramolecular self-assembly mechanism of the hydrogels was also investigated in detail through experimental characterizations and density functional theory calculation.As-prepared hydrogels also exhibit reversible pH-stimulated response and self-healing properties.This study details a research process for the simple and rapid preparation of tryptophan derivative-based hydrogels,which provides more reference ideas for the future development of materials based on other amino acid derivatives. | Xianwen Song Jun Zheng Shunmei He Yilin Liu Shutong Yang Qiang Li Chuntai Liu Zequn Zhang Xi Liu Chunyan Deng Yi Zhang | 2023 | Chinese Chemical Letters2023，34，8： | 0 |
| 17 | High-quality genome assembly and pan-genome studies facilitate genetic discovery in mung bean and its improvement显示文摘Mung bean is an economically important legume crop species that is used as a food,consumed as a vegetable,and used as an ingredient and even as a medicine.To explore the genomic diversity of mung bean,we assembled a high-quality reference genome(Vrad_JL7)that was479.35 Mb in size,with a contig N50 length of 10.34 Mb.A total of 40,125 protein-coding genes were annotated,representing96.9%of the genetic region.We also sequenced 217 accessions,mainly landraces and cultivars from China,and identified 2,229,343 high-quality single-nucleotide polymorphisms(SNPs).Population structure revealed that the Chinese accessions diverged into two groups and were distinct from non-Chinese lines.Genetic diversity analysis based on genomic data from 750 accessions in 23 countries supported the hypothesis that mung bean was first domesticated in south Asia and introduced to east Asia probably through the Silk Road.We constructed the first pan-genome of mung bean germplasm and assembled 287.73 Mb of non-reference sequences.Among the genes,83.1%were core genes and 16.9%were variable.Presence/absence variation(PAV)events of nine genes involved in the regulation of the photoperiodic flowering pathway were identified as being under selection during the adaptation process to promote early flowering in the spring.Genomewide association studies(GWASs)revealed 2,912 SNPs and 259 gene PAV events associated with 33 agronomic traits,including a SNP in the coding region of the SWEET10 homolog(jg24043)involved in crude starch content and a PAV event in a large fragment containing 11 genes for color-related traits.This high-quality reference genome and pan-genome will provide insights into mung bean breeding. | Changyou Liu Yan Wang Jianxiang Peng Baojie Fan Dongxu Xu Jing Wu Zhimin Cao Yunqing Gao Xueqing Wang Shutong Li Qiuzhu Su Zhixiao Zhang Shen Wang Xingbo Wu Qibing Shang Huiying Shi Yingchao Shen Bingbing Wang Jing Tian | 2022 | Plant Communications2022，3，6： | 0 |
| 18 | Milling degree affects the fermentation properties of rice:perspectives from the composition of nutrients and gut microbiota via in vitro fermentation显示文摘Fermentation substrates of rice with different milling degrees(MDs) were prepared and fermented with human feces to compare their fermentation properties and effects on gut microbiota.MD 0s,MD 5s and MD 60s represented brown rice,moderately-milled rice and white rice,respectively.After in vitro fermentation,the MD 5s group showed higher starch utilization,compared with the MD 0s and 60s groups evaluated by Fourier transform infrared spectrometer,and confocal laser scanning microscope.Effects of fermentation substrates of rice with different MDs on gut microbiota were evaluated by 16S rDNA sequencing.All the sample groups reduced the pH and produced short-chain fatty acids(SCFAs) and branched-chain fatty acids.The MD 5s group exhibited higher α-diversity than the MD 0s and 60s groups.Abundances of Phascolarctobacterium,Blautia and norank_f_Ruminococcaceae were higher in the MD 0s and 5s groups,compared with the MD 60s group.These bacteria were also positively correlated with the SCFAs production via Spearman correlation analysis.In vitro culture assay revealed that fermentation substrates of MD 0s and 5s promoted the growth of two probiotics(Akkermansia muciniphila and Bifidobacterium adolescentis).Our results showed that moderate milling might be an appropriate way to produce rice products with richer nutrients and better fermentation properties. | Yu Zhang Fan Li Shutong Pan Bing Bai Kai Huang Sen Li Hongwei Cao Tian Xie Jian Xie Xiao Guan | 2024 | Food Science and Human Wellness2024，13，3： | 0 |
| 19 | Instantaneous Real-Time Detection Technology of GLI on FY-4 Geostationary Meteorological Satellite显示文摘Lightning is a typical example of an instantaneous random point source target. It has close connection with severe convective phenomena such as a thunderstorm, whose distribution, variation, position and forecasting can be acquired through lightning observation. In this paper, we discuss the way to achieve instantaneous lightning signal intensification and detection from geostationary orbit by using the differences between the lightning signal and the slowly changing background noise such as that of cloud, land and ocean, combining three methods, spectral filtering, spatial filtering and background noise, enabling removal between frames. After six months of operation in orbit, lightning within the coverage of the Geostationary Lightning Imager was effectively detected, strongly supporting the case for shorttime and real-time early warning, forecasting and tracking of severe convective phenomena in China. | BAO Shutong LI Yunfei TANG Shaofan LIANG Hua ZHAO Xuemin | 2017 | Aerospace China2017，18，2： | 0 |
| 20 | Preparation of porous semi-IPN temperature-sensitive hydrogel-supported nZVI and its application in the reduction of nitrophenol显示文摘Nanoscale zero-valent iron(n ZVI) particles supported on a porous, semi-interpenetrating(semi-IPN), temperature-sensitive composite hydrogel(PNIPAm-PHEMA). n ZVI@PNIPAmPHEMA, was successfully synthesized and characterized by FT-IR, SEM, EDS, XRD and the weighing method. The loading of nZVI was 0.1548 ± 0.0015 g/g and the particle size was30–100 nm. NZVI was uniformly dispersed on the pore walls inside the PNIPAm-PHEMA.Because of the well-dispersed n ZVI, the highly porous structure, and the synergistic effect of PNIPAm-PHEMA, nZVI@PNIPAm-PHEMA showed excellent reductive activity and wide p H applicability. 95% of 4-NP in 100 m L of 400 mg/L 4-NP solution with initial p H 3.0–9.0 could be completely reduced into 4-AP by about 0.0548 g of fresh supported n ZVI at 18–25 °C under stirring(110 r/min) within 45 min reaction time. A greater than 99% 4-NP degradation ratio was obtained when the initial p H was 5.0–9.0. The reduction of 4-NP by nZVI@PNIPAm-PHEMA was in agreement with the pseudo-first-order kinetics model with Kobsvalues of 0.0885–0.101 min-1.NZVI@PNIPAm-PHEMA was able to be recycled, and about 85% degradation ratio of 4-NP was obtained after its sixth reuse cycle. According to the temperature sensitivity of PNIPAmPHEMA, n ZVI@PNIPAm-PHEMA exhibited very good storage stability, and about 88.9%degradation ratio of 4-NP was obtained after its storage for 30 days. The hybrid reducer was highly efficient for the reduction of 2-NP, 3-NP, 2-chloro-4-nitrophenol and 2-chloro-4-nitrophenol. Our results suggest that PNIPAm-PHEMA could be a good potential carrier, with n ZVI@PNIPAm-PHEMA having potential value in the application of reductive degradation of nitrophenol pollutants. | Lixia Li Ruiwei Wang Xiaodong Xing Wenqiang Qu Shutong Chen Yunlong Zhang | 2019 | Journal of Environmental Sciences2019，31，8： | 0 |
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