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| 1 | Palaeoproterozoic Khondalite Belt in the western North China Craton: New evidence from SHRIMP dating and Hf isotope composition of zircons from metamorphic rocks in the Bayan Ul-Helan Mountains area显示文摘Zircom U-Pb age and Hf isotope analyses were made on gneissic granite and garnet-mica two-feldspar gneiss from the Helanshan Group in the Bayan Ul-Helan Mountains area, the western block of the North China Craton (NCC). Zircons from the gneissic granite commonly show core-mantle-rim structures, with magmatic core, metamorphic mantle and rim having ages of 2323±20 Ma, 1923±28 Ma and 1856±12 Ma, respectively. The core, mantle and rim show similar Hf isotope compositions, with single-stage depleted mantle model ages (TDM1) of 2455 to 2655 Ma (19 analyses). Most of the detrital zircons from the garnet-mica two-feldspar paragneiss have a concentrated U-Pb age distribution, with a weighted mean 207Pb/206Pb age of 1978±17 Ma. A few detrital zircons are older (2871 to 2469 Ma). The age for metamorphic overgrown rim was not determined because of strong Pb loss due to their high U content. The zircons show large variation in Hf isotope composition, with TDM1 ages of 1999 to 3047 Ma. In com- bination with previous studies, the main conclusions are as follows: (1) protolith of the khondalite se- ries in the Helanshan Group formed during Palaeoproterozoic rather than the Archaean as previously considered; (2) The results lend support to the contention that there is a huge Palaeoproterozoic Khondalite (metasedimentary) Belt between the Yinshan Mountains Block and the Ordos Block in the Western Block of NCC; (3) The widely-distributed bodies of early Palaeoproterozoic orthogneisses in the Khondalite Belt might be one of the important sources for detritus material in the khondalite series; (4) Collision between the Yinshan Block, the Ordos Block and the Eastern Block occurred in the same tectonothermal event of late Palaeoproterozoic, resulting in the final assembly of the NCC. | DONG ChunYan LIU DunYi LI JunJian WAN YuSheng ZHOU HongYing LI ChengDong YANG YueHeng XIE LieWen | 2007 | Chinese Science Bulletin2007，52，21： | 52 |
| 2 | Viscoelasticity of repaired sciatic nerve by poly(lactic-co-glycolic acid) tubes显示文摘Medical-grade synthetic poly(lactic-co-glycolic acid) polymer can be used as a biomaterial for nerve repair because of its good biocompatibility,biodegradability and adjustable degradation rate.The stress relaxation and creep properties of peripheral nerve can be greatly improved by repair with poly(lactic-co-glycolic acid) tubes.Ten sciatic nerve specimens were harvested from fresh corpses within 24 hours of death,and were prepared into sciatic nerve injury models by creating a 10 mm defect in each specimen.Defects were repaired by anastomosis with nerve autografts and poly(lactic-co-glycolic acid) tubes.Stress relaxation and creep testing showed that at 7 200 seconds,the sciatic nerve anastomosed by poly(lactic-co-glycolic acid) tubes exhibited a greater decrease in stress and increase in strain than those anastomosed by nerve autografts.These findings suggest that poly(lactic-co-glycolic acid) exhibits good viscoelasticity to meet the biomechanical requirements for a biomaterial used to repair sciatic nerve injury. | Chengdong Piao Peng Li Guangyao Liu Kun Yang | 2013 | Neural Regeneration Research2013，8，33： | 4 |
| 3 | Fabrication of single-walled carbon nanotube-based highly sensitive gas sensors显示文摘A highly sensitive single-walled carbon nanotube(SWCNT)-based ammonia(NH3) gas detector is manufactured by orderly assembling SWCNT using the dielectrophoretical(DEP) technology.Atom force microscopy(AFM) and scanning electron microscopy(SEM) images revealed that SWCNTs were assembled between the microelectrodes.SWCNTs were affected by the electrophoretic force which was carried out by the related theoretical analysis in a nonuniform electric field.The SWCNT field effect transistors geometry was obtained.The electrical performance of NH3 gas sensor with the SWCNT field effect transistors geometry was tested before and after the adoption of NH3 at room temperature.Experimental results indicated that the efficient assembly of SWCNT was obtained by the applied alternating current voltage with frequency of 2 MHz and amplitude of 10 V.The SWCNTs-based gas sensor had high sensitivity to NH3,and the electrical conductance of NH3 gas sensor reduced two times after interaction with NH3.The SWCNTs surface gas molecules were removed by means of ultraviolet ray irradiation for 10 min.Hence,the fabricated NH3 gas sensor could be reversible.There is a clear evidence that the adsorption of NH3 on the SWCNT channel is easy to be realized.Our theoretical results are consistent with recent experiments. | XU Ke TIAN XiaoJun WU ChengDong LIU Jian LI MengXin SUN Ying WEI FaNan | 2013 | Science China(Technological Sciences)2013，56，1： | 4 |
| 4 | A new Cu^(2+)-induced color reaction of a rhodamine derivative N-(3-carboxy)acryloyl rhodamine B hydrazide显示文摘A new rhodamine derivative,N-(3-carboxy)acryloyl rhodamine B hydrazide(CARB),has been synthesized,and its unusual spectroscopic reaction with Cu2+ has been investigated.The derivative exhibits a rapid and reversible non-fluorescent absorption upon coordination to Cu2+,which is a rather unusual phenomenon for rhodamine B derivatives.Stoichiometric measurements using the Job's method and the molar ratio method reveal that one CARB molecule combines two Cu2+ ions,and the two Cu2+ ions play different roles:one opens the spirocyclic structure and the other quenches the fluorescence of the xanthene moiety.This reaction mechanism is supported by a comparative study on the model compound N-acryloyl rhodamine B hydrazide as well as by the density functional theory calculations.Furthermore,the absorption response of CARB is highly selective for Cu2+ over other common ions,which implies that CARB may be used as a colorimetric probe for the rapid visual detection of Cu2+. | SUN ChengDong CHEN JianMing MA HuiMin LIU Yang ZHANG JingHua LIU QingJun | 2011 | Science China Chemistry2011，54，7： | 3 |
| 5 | Numerical Study of Effect of Compressor Swirling Flow on Combustor Design in a MTE显示文摘An effect of the swirling flow on the combustion performance is studied by the computational fluid dynamics(CFD) in a micro-gas turbine with a centrifugal compressor, dump diffuser and forward-flow combustor. The distributions of air mass and the Temperature Pattern Factor(as: Overall Temperature Distribution Factor-OTDF) in outlet are investigated with two different swirling angles of compressed air as 0° and 15° in three combustors. The results show that the influences of swirling flow on the air distribution and OTDF cannot be neglected. Compared with no-swirling flow, the air through outer liner is more, and the air through the inner liner is less, and the pressure loss is bigger under the swirling condition in the same combustor. The Temperature Pattern Factor changes under the different swirling conditions. | MU Yong WANG Chengdong LIU Cunxi LIU Fuqiang HU Chunyan XU Gang ZHU Junqiang | 2017 | Journal of Thermal Science2017，26，4： | 3 |
| 6 | Study on the large-scale assembly and fabrication method for SWCNTs nano device显示文摘The large-scale assembly and fabrication method for single-walled carbon nanotube(SWCNT) nano devices was implemented.Assembly of SWCNT field effect transistor(FET) was realized by floating potential dielectrophoresis approach.The simulation of floating potential distribution of the chip was performed by comsol multiphysics coupling software.Six hundred devices were assembled on the area of less than one square centimeter.The fabricated devices were characterized by atomic force microscopy and scanning electron microscopy.The experimental results showed that large-scale assembly had been realized,and the success rate of ideal assembly for SWCNT FET had been assessed. | XU Ke TIAN XiaoJun WU ChengDong LIU Jian LI MengXin DONG ZaiLi | 2013 | Science China Chemistry2013，56，3： | 3 |
| 7 | Mechanical properties and microstructure of 3D orthogonal quartz fiber reinforced silica composites fabricated by silicasol-infiltration-sintering显示文摘 | Chengdong Li Zhaofeng Chen Jianxun Zhu Yong Liu Yun Jiang Tianru Guan Binbin Li Long Lin | 2011 | Materials and Design2011，，： | 1 |
| 8 | Numerica simulation of inertia friction welding process of GH4169 alloy显示文摘 | Zhang Liwen Liu Chengdong Qi Shaoan | 2004 | Journal de Physique IV2004，120，11： | 1 |
| 9 | PRESSURE GRADIENT FROM THE CONTRIBUTION OF BOTH GEOTHERMAL AND GRAVITY IN THE LITHOSPHERE显示文摘The pressure gradient of the lithosphere is a key to explaining various geological processes, and varies also in time and space similar to the geothermal gradient. In this paper a correlation formula of geothermal gradients and pressure gradients was built with the thermocomprestion coefficients. Based on this formula, the article has studied the relation between the pressure gradients and the geothermal gradients in the lithosphere, and the results indicate that the pressure gradient in the lithosphere is nonlinear, and its minimum value is the lithostatic gradient, and that the pressure gradient of the lithosphere will increase obviously with the contribution of both geothermal and gravity, and could be twice times more than the lithostatic gradient. | HU Baoqun LU Guxian WANG Fangzhang SUN Zhanxue LIU Chengdong BAI Lihong | 2005 | Geotectonica et Metallogenia2005，29，2： | 1 |
| 10 | The Distinguished Involutions with a value n^2-3n+3 in the Weyl Group of Type Dn显示文摘 | CHEN Chengdong LIU Jiachun | 2003 | Journal of Algebra(S0092-7892)2003，265，： | 1 |
| 11 | On Certain Distinguishable Involutions of the Weyl Group of Type Dn显示文摘 | CHEN Chengdong LIU Jiachun | 2004 | Journal of Algebra(S0092-7892)2004，274，： | 1 |
| 12 | Kazhdan-Lusztig Basis Elements in the Hecke Algebra of Type Bn and Dn显示文摘 | CHEN Chengdong LIU Jiachun | 2004 | Algebra Colloquium(S1005-3867)2004，11，3： | 1 |
| 13 | Remarkably enhanced piezo-photocatalytic performance in BaTiO_(3)/CuO heterostructures for organic pollutant degradation显示文摘Introducing polarization field of piezoelectric materials is an effective strategy to improve photocatalytic performance.In this study,a new type of BaTiO_(3)/CuO heterostructure catalyst was designed and synthesized to achieve high piezo-photocatalytic activity through the synergy of heterojunction and piezoelectric effect.The BaTiO_(3)/CuO heterostructure shows a significantly enhanced piezo-photocatalytic degradation efficiency of organic pollutants compared with the individual BaTiO_(3) nanowires(NWs)and CuO nanoparticles(NPs).Under the co-excitation of ultrasonic vibration and ultraviolet radiation,the optimal degradation reaction rate constant k of polarized BaTiO_(3)/CuO heterostructure on methyl orange(MO)dye can reach 0.05 min^(−1),which is 6.1 times of photocatalytic rate and 7 times of piezocatalytic rate.The BaTiO_(3)/CuO heterostructure with remarkable piezo-photocatalytic behavior provides a promising strategy for the development of high-efficiency catalysts for wastewater purification,and it also helps understand the coupling mechanism between piezoelectric effect and photocatalysis. | Chenye YU Mengxi TAN Chengdong TAO Yuxuan HU Chuanbao LIU Huimin MENG Yanjing SU Lijie QIAO Yang BAI | 2022 | Journal of Advanced Ceramics2022，11，3： | 1 |
| 14 | Recent advances in amino acid sensing and new challenges for protein nutrition in aquaculture显示文摘From the conventional knowledge of protein nutrition to the molecular nutrition of amino acids, our understanding of protein/amino acid nutrition is rapidly increasing. Amino acids control cell growth and metabolism through two amino acid-sensingpathways, i.e. target of rapamycin complex 1 (TORC1) and the general control nonderepressible 2 (GCN2) signaling pathway.In the amino acid-abundant status, TORC1 dominates intracellular signaling and increases protein synthesis and cell growth.In contrast, amino acid deprivation actives GCN2 resulting in repression of general protein synthesis but facilitates the aminoacid transport and synthesis process. By integrating and coordinating nutrition and hormone signaling, TORC1 and GCN2control the switch of the catabolism and anabolism phase in most eukaryotes. Now, we appreciate that the availability ofindividual amino acids is sensed by intracellular sensors. These cutting-edge findings expand our knowledge of amino acidnutrition. Although the TORC1 and GCN2 were discovered decades ago, the study of molecular amino acid nutrition inaquaculture animals is still at its infancy. The aquaculture industry is highly dependent on the supply of fishmeal, which isthe major protein source in aquacultural animal diets. Some concerted efforts were conducted to substitute for fishmeal dueto limited supply of it. However, the concomitant issues including the unbalanced amino acid profile of alternative proteinsources limited the utilization of those proteins. Continued study of the molecular nutrition of amino acid in aquacultureanimals may be expected in the immediate future to expand our knowledge on the utilization of alternative protein sources. | Chengdong Liu Xuan Wang Huihui Zhou Kangsen Mai Gen He | 2019 | Marine Life Science & Technology2019，1，1： | 1 |
| 15 | Electron-ion collider in China显示文摘Lepton scattering is an established ideal tool for studying inner structure of small particles such as nucleons as well as nuclei.As a future high energy nuclear physics project,an Electron-ion collider in China(EicC)has been proposed.It will be constructed based on an upgraded heavy-ion accelerator,High Intensity heavy-ion Accelerator Facility(HIAF)which is currently under construction,together with a new electron ring.The proposed collider will provide highly polarized electrons(with a po-larization of 80%)and protons(with a polarization of 70%)with variable center of mass energies from 15 to 20 GeV and the luminosity of(2–3)×1033 cm^(−2)·s^(−1).Polarized deuterons and Helium-3,as well as unpolarized ion beams from Carbon to Uranium,will be also available at the EicC.The main foci of the EicC will be precision measurements of the structure of the nucleon in the sea quark region,including 3D tomography of nucleon;the partonic structure of nuclei and the parton interaction with the nuclear environment;the exotic states,especially those with heavy flavor quark contents.In addition,issues fundamental to understanding the origin of mass could be addressed by measurements of heavy quarkonia near-threshold production at the EicC.In order to achieve the above-mentioned physics goals,a hermetical detector system will be constructed with cutting-edge technologies.This document is the result of collective contributions and valuable inputs from experts across the globe.The EicC physics program complements the ongoing scientific programs at the Jefferson Laboratory and the future EIC project in the United States.The success of this project will also advance both nuclear and particle physics as well as accelerator and detector technology in China. | Daniele PAnderle Valerio Bertone Xu Cao Lei Chang Ningbo Chang Gu Chen Xurong Chen Zhuojun Chen Zhufang Cui Lingyun Dai Weitian Deng Minghui Ding Xu Feng Chang Gong Longcheng Gui Feng-Kun Guo Chengdong Han Jun He Tie-Jiun Hou Hongxia Huang Yin Huang KrešImir KumeričKi LPKaptari Demin Li Hengne Li Minxiang Li Xueqian Li Yutie Liang Zuotang Liang Chen Liu Chuan Liu Guoming Liu Jie Liu Liuming Liu Xiang Liu Tianbo Liu Xiaofeng Luo Zhun Lyu Boqiang Ma Fu Ma Jianping Ma Yugang Ma Lijun Mao Cédric Mezrag HervéMoutarde Jialun Ping Sixue Qin Hang Ren Craig DRoberts Juan Rojo Guodong Shen Chao Shi Qintao Song Hao Sun PawełSznajder Enke Wang Fan Wang Qian Wang Rong Wang Ruiru Wang Taofeng Wang Wei Wang Xiaoyu Wang Xiaoyun Wang Jiajun Wu Xinggang Wu Lei Xia Bowen Xiao Guoqing Xiao Ju-Jun Xie Yaping Xie Hongxi Xing Hushan Xu Nu Xu Shusheng Xu Mengshi Yan Wenbiao Yan Wencheng Yan Xinhu Yan Jiancheng Yang Yi-Bo Yang Zhi Yang Deliang Yao Zhihong Ye Peilin Yin C-PYuan Wenlong Zhan Jianhui Zhang Jinlong Zhang Pengming Zhang Yifei Zhang Chao-Hsi Chang Zhenyu Zhang Hongwei Zhao Kuang-Ta Chao Qiang Zhao Yuxiang Zhao Zhengguo Zhao Liang Zheng Jian Zhou Xiang Zhou Xiaorong Zhou Bingsong Zou Liping Zou | 2021 | Frontiers of physics2021，16，6： | 1 |
| 16 | Research on Rare Earth Encapsulated Luminescent Material显示文摘A new method of preparation of irradiative material by using rare earth as luminophor and inorganic powder as base nucleus was presented.Rare earth was used to make colloid, which was mixed with base nucleus solution,where deposition/attachment reaction took place and rare earth was adhered onto the surface of base nucleus, hence yielding a new rare earth encapsulated irradiative material.Fluorescent spectrum analysis shows that this material possesses two emission peaks, one within 400 ~ 500 nm and the other within 580 ~ 700 nm, reflecting the luminous characteristics of original rare earth material. | Yu Zhiwei Liu Chengdong Qi Xiaopeng | 2004 | Journal of Rare Earths2004，22，z1： | 0 |
| 17 | 5′-tiRNA-Gln inhibits hepatocellular carcinoma progression by repressing translation through the interaction with eukaryotic initiation factor 4A-I显示文摘tRNA-derived small RNAs(tsRNAs)are novel non-coding RNAs that are involved in the occurrence and progression of diverse diseases.However,their exact presence and function in hepatocellular carcinoma(HCC)remain unclear.Here,differentially expressed tsRNAs in HCC were profiled.A novel tsRNA,tRNAGln-TTG derived 5′-tiRNA-Gln,is significantly downregulated,and its expression level is correlated with progression in patients.In HCC cells,5′-tiRNA-Gln overexpression impaired the proliferation,migration,and invasion in vitro and in vivo,while 5′-tiRNA-Gln knockdown yielded opposite results.5′-tiRNA-Gln exerted its function by binding eukaryotic initiation factor 4A-I(EIF4A1),which unwinds complex RNA secondary structures during translation initiation,causing the partial inhibition of translation.The suppressed downregulated proteins include ARAF,MEK1/2 and STAT3,causing the impaired signaling pathway related to HCC progression.Furthermore,based on the construction of a mutant 5′-tiRNA-Gln,the sequence of forming intramolecular G-quadruplex structure is crucial for 5′-tiRNA-Gln to strongly bind EIF4A1 and repress translation.Clinically,5′-tiRNA-Gln expression level is negatively correlated with ARAF,MEK1/2,and STAT3 in HCC tissues.Collectively,these findings reveal that 5′-tiRNA-Gln interacts with EIF4A1 to reduce related mRNA binding through the intramolecular Gquadruplex structure,and this process partially inhibits translation and HCC progression. | Chengdong Wu Dekai Liu Lufei Zhang Jingjie Wang Yuan Ding Zhongquan Sun Weilin Wang | 2023 | Frontiers of Medicine2023，17，3： | 0 |
| 18 | Genome-wide identification and spatiotemporal expression profiling of zinc finger SWIM domain-containing protein family genes显示文摘The biological function of the novel zinc-finger SWIM domain-containing protein family(ZSWIM)during embryonic development remains elusive.Here,we conducted a genome-wide analysis to explore the evolutionary processes of the ZSWIM gene family members in mice,Xenopus tropicalis,zebrafish,and humans.We identified nine putative ZSWIM genes in the human and mouse genome,eight in the Xenopus genome,and five in the zebrafish genome.Based on multiple sequence alignment,three members,ZSWIM5,ZSWIM6,and ZSWIM8,demonstrated the highest homology across all four species.Using available RNA sequencing(RNAseq)data,ZSWIM genes were found to be widely expressed across different tissues,with distinct tissuespecific properties.To identify the functions of the ZSWIM protein family during embryogenesis,we examined temporal and spatial expression patterns of zswim family genes in Xenopus embryos.Quantitative real-time polymerase chain reaction(qRT-PCR)revealed that each member had a distinct expression profile.Whole-mount in situ hybridization showed that both zswim1 and zswim3 were maternally expressed genes;zswim5 and zswim6were expressed throughout embryogenesis and displayed dynamic expression in the brain,eyes,somite,and bronchial arch at the late tailbud stages;zswim7 was detected in the eye area;zswim8 showed a dynamic expression pattern during the tailbud stages,with expression detected in the brain,eyes,and somite;zswim9 was faintly expressed throughout embryonic development.This study provides a foundation for future research to delineate the functions of ZSWIM gene members. | Imtiaz Ul Hassan Hafiz Mamoon Rehman Ziran Liu Liangji Zhou Muhammad Kaleem Samma Chengdong Wang Zixin Rong Xufeng Qi Dongqing Cai Hui Zhao | 2023 | Zoological Research2023，44，3： | 0 |
| 19 | Elevated Kir2.1/nuclear N2ICD defines a highly malignant subtype of non-WNT/SHH medulloblastomas显示文摘Medulloblastoma(MB)is one of the most common childhood malignant brain tumors(WHO grade IV),traditionally divided into WNT,SHH,Group 3,and Group 4 subgroups based on the transcription profiles,somatic DNA alterations,and clinical outcomes.Unlike WNT and SHH subgroup MBs,Group 3 and Group 4 MBs have similar transcriptomes and lack clearly specific drivers and targeted therapeutic options.The recently revised WHO Classification of CNS Tumors has assigned Group 3 and 4 to a provisional non-WNT/SHH entity.In the present study,we demonstrate that Kir2.1,an inwardly-rectifying potassium channel,is highly expressed in non-WNT/SHH MBs,which promotes tumor cell invasion and metastasis by recruiting Adam10 to enhance S2 cleavage of Notch2 thereby activating the Notch2 signaling pathway.Disruption of the Notch2 pathway markedly inhibited the growth and metastasis of Kir2.1-overexpressing MB cell-derived xenograft tumors in mice.Moreover,Kir2.1^(high)/nuclear N2ICD^(high)MBs are associated with the significantly shorter lifespan of the patients.Thus,Kir2.1^(high)/nuclear N2ICD^(high)can be used as a biomarker to define a novel subtype of non-WNT/SHH MBs.Our findings are important for the modification of treatment regimens and the development of novel-targeted therapies for non-WNT/SHH MBs. | Yan-Xia Wang Haibo Wu Yong Ren Shengqing Lv Chengdong Ji Dongfang Xiang Mengsi Zhang Huimin Lu Wenjuan Fu Qing Liu Zexuan Yan Qinghua Ma Jingya Miao Ruili Cai Xi Lan Bin Wu Wenying Wang Yinhua Liu Dai-Zhong Wang Mianfu Cao Zhicheng He Yu Shi Yifang Ping Xiaohong Yao Xia Zhang Peng Zhang Ji Ming Wang Yan Wang Youhong Cui Xiu-Wu Bian | 2022 | Signal Transduction and Targeted Therapy2022，7，4： | 0 |
| 20 | The effect of macropore size of hydroxyapatite scaffold on the osteogenic differentiation of bone mesenchymal stem cells under perfusion culture显示文摘Previous studies have proved that dynamic culture could facilitate nutrients transport and apply mechanical stimulation to the cells within three-dimensional scaffolds,thus enhancing the differentiation of stem cells towards the osteogenic phenotype.However,the effects of macropore size on osteogenic differentiation of stem cells under dynamic condition are still unclear.Therefore,the objective of this study was to investigate the effects of macropore size of hydroxyapatite(HAp)scaffolds on osteogenic differentiation of bone mesenchymal stem cells under static and perfusion culture conditions.In vitro cell culture results showed that cell proliferation,alkaline phosphate(ALP)activity,mRNA expression of ALP,collagen-I(Col-I),osteocalcin(OCN)and osteopontin(OPN)were enhanced when cultured under perfusion condition in comparison to static culture.Under perfusion culture condition,the ALP activity and the gene expression of ALP,Col-I,OCN and OPN were enhanced with the macropore size decreasing from 1300 to 800 mm.However,with the further decrease in macropore size from 800 to 500 mm,the osteogenic related gene expression and protein secretion were reduced.Computational fluid dynamics analysis showed that the distribution areas of medium-and high-speed flow increased with the decrease in macropore size,accompanied by the increase of the fluid shear stress within the scaffolds.These results confirm the effects of macropore size on fluid flow stimuli and cell differentiation,and also help optimize the macropore size of HAp scaffolds for bone tissue engineering. | Feng Shi Dongqin Xiao Chengdong Zhang Wei Zhi Yumei Liu Jie Weng | 2021 | Regenerative Biomaterials2021，8，6： | 0 |
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