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| 1 | Aqueous extract of Taxus Chinensis (Pilger) Rehd inhibits lung carcinoma A549 cells through the epidermal growth factor receptor/mitogen-activated protein kinase pathway in vitro and in vivo显示文摘OBJECTIVE:To explore the anticancer mechanismof aqueous extract of Taxus Chinensis (Pilger) Rehd (AETC).METHODS: The serum pharmacological method was used to avoid interference from administration of the crude medicinal herbs. Eight purebred New Zealand rabbits were used for preparation of serum containing various concentrations of AETC. Forty-eightBalb/c-nu mice were used for in vivo experiments. The effects of serum containing AETC on the proliferation of A549 cells and expression levels of the epidermal growth factor receptor/mitogen-activated protein kinase(EGFR/MAPK) pathway-related proteins in vitro were investigated. Additionally, the effects on the growth of A549 xenografts in nudemice,and expression levels of the EGFR/MAPK pathway-related proteins in the xenografts,were investigated.RESULTS: 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide(MTT) assay revealed that the serum containing AETC significantly decreased the viability of A549 cells in a dose-dependent manner.Western blot showed that the serum containing various concentrations of AETC strongly reduced the levels of phospho-Jun N-terminal kinase(p-JNK) and phospho-extracellular signal-regulated kinase1/2(ERK1/2) while it increased the level of p-p38. However, no significant effects on the expression levels of JNK, ERK1/2, and p38 MAPK were found. In addition, an anticancer effect from AETC was observed invivo in the Balb/c-nu mice bearing A549xenografts.CONCLUSION: AETC has significant effects on the growth of A549 xenografts and on the activity of the EGFR/MAPK pathway. Therefore, AETC may be beneficial in lung carcinoma treatment. | Qijin Shu Minhe Shen Binbin Wang Qingli Cui Xiaoying Zhou Luming Zhu | 2014 | Journal of Traditional Chinese Medicine2014，34，3： | 10 |
| 2 | Effects of baicalein on pancreatic cancer stem cells via modulation of sonic Hedgehog pathway显示文摘 | Libin Song Xiangyuan Chen Peng Wang Song Gao Chao Qu Luming Liu | 2018 | Acta Biochimica et Biophysica Sinica2018，50，6： | 10 |
| 3 | STUDY ON MECHANISM OF ARC-EXCITED ULTRASONIC显示文摘0INTRODUCTIONAnelectricalarccanbeidentifiedasadynamicresistanceinanarcweldingcircuit.Itistriedsucesfulyintungsteninertgasarcw... | Wu Minsheng Wang Zhengxian Li Luming Sun Diqing Duan Xiangyang Department of Mechanical Engineering, Qinghua University | 1999 | Chinese Journal of Mechanical Engineering1999，12，1： | 8 |
| 4 | Carbothermic reduction of vanadium titanomagnetite with the assistance of sodium carbonate显示文摘The carbothermic reduction of vanadium titanomagnetite concentrate(VTC)with the assistance of Na_(2)CO_(3)was conducted in an argon atmosphere between 1073 and 1473 K.X-ray diffraction and scanning electron microscopy were used to investigate the phase transformations during the reaction.By investigating the reaction between VTC and Na_(2)CO_(3),it was concluded that molten Na_(2)CO_(3)broke the structure of titanomagnetite by combining with the acidic oxides(Fe_(2)O_(3),TiO_(2),Al_(2)O_(3),and SiO_(2))to form a Na-rich melt and release FeO and MgO.Therefore,Na_(2)CO_(3)accelerated the reduction rate.In addition,adding Na_(2)CO_(3)also benefited the agglomeration of iron particles and the slag–metal separation by decreasing the viscosity of the slag.Thus,Na_(2)CO_(3)assisted carbothermic reduction is a promising method for treating VTC at low temperatures. | Luming Chen Yulan Zhen Guohua Zhang Desheng Chen Lina Wang Hongxin Zhao Fancheng Meng Tao Qi | 2022 | International Journal of Minerals,Metallurgy and Materials2022，29，2： | 5 |
| 5 | Spatial and temporal variabilities of rainstorms over China under climate change显示文摘Rainstorms are one of the extreme rainfall events that cause serious disasters,such as urban flooding and mountain torrents.Traditional studies have used rain gauge observations to analyze rainstorm events,but relevant information is usually missing in gauge-sparse areas.Satellite-derived precipitation datasets serve as excellent supplements or substitutes for the gauge observations.By developing a grid-based rainstorm-identification tool,we used the Tropical Rainfall Measurement Mission(TRMM)Multi-satellite Precipitation Analysis(TMPA)time series product to reveal the spatial and temporal variabilities of rainstorms over China during 1998–2017.Significant patterns of both increasing and decreasing rainstorm occurrences were detected,with no spatially uniform trend being observed across the whole country.There was an increase in the area being affected by rainstorms during the 20-year period,with rainstorm centers shifting along the southwest–northeast direction.Rainstorm occurrence was found to be correlated with local total precipitation.By comparing rainstorm occurrence with climate variables such as the El Ni?o-Southern Oscillation and Pacific Decadal Oscillation,we also found that climate change was likely to be the primary reason for rainstorm occurrence in China.This study complements previous studies that used gauge observations by providing a better understanding of the spatiotemporal dynamics of China’s rainstorms. | HUANG Chang ZHANG Shiqiang DONG Linyao WANG Zucheng LI Linyi CUI Luming | 2021 | Journal of Geographical Sciences2021，31，4： | 3 |
| 6 | Ultrahigh rate capability of 1D/2D polyaniline/titanium carbide(MXene)nanohybrid for advanced asymmetric supercapacitors显示文摘High energy density and enhanced rate capability are highly sought-after for supercapacitors in today's mobile world.In this work,polyaniline/titanium carbide(MXene)(PANI/Ti3C2Tx)nanohybrid is synthesized through a facile and cost-effective self-assembly of.one-dimensional(10)PANI nanofibers and two-dimensional(20)Ti3C2Tx nanosheets.PANl!Ti3C2Tx delivers greatly improved specific capacitance,ultrahigh rate capability(67%capacitance retention from 1 to 100 A·g^(-1))as well as good cycle stability.Electrochemical kinetic analysis reveals that PANI/Ti3C2Tx is featured with surface capacitance-dominated process and has a quasi-reversible kinetics at high scan rates,giving rise to an ultrahigh rate capability.By using PANl!Ti3C2Tx as positive electrode,an 1.8 V aqueous asymmetric supercapacitor(ASC)is successfully assembled,showing a maximum energy density of 50.8 Wh·kg^(-1)·(at 0.9 kW-kg-1)and a power density of 18 kW·kg^(-1)(at 26 Wh·kg^(-1)).Moreover,an 3.0 V organic ASC is also elaborately fabricated,·by using PANI/Ti3C2Tx,achieving an ultrahigh energy density of 67.2 Wh·kg^(-1)(at 1.5 kW·kg^(-1))and a power density of 30 kW·kg^(-1)·(at 26.8 Wh·kg^(-1)).The present work not only improves fundamental understanding of the structure-property relationship towards ultrahigh rate capability electrode materials,but also provides valuable guideline for the rational design of high-performance:energy storage devices with both high energy and power densities. | Jinhua Zhou Qi Kang Shuchi Xu Xiaoge Li Cong Liu Lu Ni Ningna Chen Chunliang Lu Xizhang Wang Luming Peng Xuefeng Guo Weiping Ding Wenhua Hou | 2022 | Nano Research2022，15，1： | 2 |
| 7 | Shrinking target problems for beta-dynamical system显示文摘For any β>1,let([0,1],Tβ) be the beta dynamical system.For a positive function ψ:N→R+ and a real number x0 ∈[0,1],we define D(Tβ,ψ,x0) the set of ψ-well approximable points by x0as {x∈[0,1]:|Tβnx-x0|<ψ(n) for infinitely many n∈N}.In this note,by proving a structure lemma that any ball B(x,r) contains a regular cylinder of comparable length with r,we determine the Hausdorff dimension of the set D(Tβ,ψ,x0) completely for any β>1 and any positive function ψ. | SHEN LuMing WANG BaoWei | 2013 | Science China Mathematics2013，56，1： | 2 |
| 8 | Research on magnetic testing method of stress distribution显示文摘 | LI Luming Huang Songling Wang Laifu | 2002 | Transaction of Nonferrous Metals Society of China2002，12，3： | 1 |
| 9 | Influ- ence of operating conditions on extracellular polymeric sub- stances and surface properties of sludge floes显示文摘 | WANG Hongwu DENG Huanhuan MA Luming | 2013 | Carbohy- drate Polymers2013，92，1： | 1 |
| 10 | Hierarchically porous Fe/N/S/C nanospheres with high-content of Fe-Nx for enhanced ORR and Zn-air battery performance显示文摘Heteroatom-doped carbon-based transition-metal single-atom catalysts(SACs) are promising electrocatalysts for oxygen reduction reaction(ORR). Herein, with the aid of hierarchically porous silica as hard template, a facile and general melting perfusion and mesopore-confined pyrolysis method was reported to prepare single-atomic Fe/N–S-doped carbon catalyst(FeNx/NC-S) with hierarchically porous structure and well-defined morphology. The FeNx/NC-S exhibited excellent ORR activity with a half-wave potential(E_(1/2)) of 0.92 V, and a lower overpotential of 320 mV at a current density of 10 mA cm^(-2)for OER under alkaline condition. The remarkable electrocatalysis performance can be attributed to the hierarchically porous carbon nanospheres with S doping and high content of Fe-Nx sites(up to 3.7 wt% of Fe), resulting from the nano-confinement effect of the hierarchically porous silica spheres(NKM-5) during the pyrolysis process. The rechargeable Zn-air battery with FeNx/NC-S as a cathode catalyst demonstrated a superior power density of 194.5 mW cm-2charge–discharge stability. This work highlights a new avenue to design advanced SACs for efficient sustainable energy storage and conversion. | Luming Wu Ruge Zhao Guo Du Huan Wang Machuan Hou Wei Zhang Pingchuan Sun Tiehong Chen | 2023 | Green Energy & Environment2023，8，6： | 1 |
| 11 | Magnetic field abnormality caused by welding residual stress显示文摘 | Li Luming Huang Songling Wang Xiaofeng | 2003 | Journal of Magnetism and Magnetic Materials2003，，261： | 1 |
| 12 | Conservative sehemes for the symmetric regularized long wave equations 显示文摘 | Wang Tingchun Zhang Luming Chen Fangqi | 2007 | Applied Mathematics and Computation2007，190，： | 1 |
| 13 | Optimization of extraction procedure for formaldehyde assay in smoked meat products显示文摘 | Yi Zhu Zengqi Peng Min Wang Rongrong Wang Luming Rui | 2012 | Journal of Food Composition and Analysis2012，，： | 1 |
| 14 | Split-step orthogonal spline collocation methods for nonlinear Schr?dinger equations in one, two, and three dimensions显示文摘 | Shanshan Wang Luming Zhang | 2011 | Applied Mathematics and Computation2011，，5： | 1 |
| 15 | Iron shavings supported biological denitrification in sequencing batch reactor显示文摘 | Wang Zi Wang Hongwu Ma Luming | 2012 | Desalin Water Treat2012，49，123： | 1 |
| 16 | Magnetic field abnormality caused by welding residual stress显示文摘 | Li Luming Huang Songling Wang Xiaofeng Shi Keren Wu Su | 2002 | Journal of Magnetism and Magnetic Materials2002，，3： | 1 |
| 17 | The serum miR-21 level serves as a predictor for the chemosensitivity of advanced pancreatic cancer, and miR-21 expression confers chemoresistance by targeting FasL显示文摘 | Peng Wang Liping Zhuang Juan Zhang Jie Fan Jianmin Luo Hao Chen Kun Wang Luming Liu Zhen Chen Zhiqiang Meng | 2013 | Molecular Oncology2013，，3： | 1 |
| 18 | Conservative difference scheme based on numerical analysis for nonlinear SchrSdinger equation with wave operator显示文摘 | Wang Tingchun Zhang Luming Chen Fangqi | 2006 | Trans Nanjing Univ of Aero &: Astron2006，23，2： | 1 |
| 19 | A compact finite difference scheme for the nonlinear Schr?dinger equation with wave operator显示文摘 | Xin Li Luming Zhang Shanshan Wang | 2012 | Applied Mathematics and Computation2012，，6： | 1 |
| 20 | A compact finite difference scheme for the nonlinear SchrSdinger equation with wave operator显示文摘 | Li Xin Zhang Luming Wang Shanshan | 2012 | Appl Math Comput2012，219，： | 1 |
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