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| 1 | 持续气道正压通气在预防阻塞性睡眠呼吸暂停患者心血管事件中的作用显示文摘阻塞性睡眠呼吸暂停(obstructive sleep apnea,OSA)导致阵发性低氧血症,夜间交感神经系统激活,血压、氧化应激和炎症指标的升高以及高凝血症。较大的胸内负压波动也会给心脏和大血管施加机械应力。基于人群和睡眠诊所的队列研究显示,OSA与心脑血管事件,特别是脑卒中相关。 | McEvoy RD Antic NA Heeley E Luo Y Ou Q Zhang X Mediano O Chen R Drager LF Liu Z Chen G Du B McArdle N Mukherjee S Tripathi M Billot L Li Q Lorenzi-Filho G Barbe F Redline S Wang J Arima H Neal B White DP Grunstein RR Zhong N Anderson CS 练桂丽 叶鹏 | 2016 | 中华高血压杂志2016，24，11： | 4 |
| 2 | Telaprevir for retreatment of HCV infection 显示文摘 | Zeuzem S Andreone P Pol S Lawitz E Diago M Roberts S Foeaccia R Younossi Z Foster GR Horban A Ferenci P Nevens F Mullhaupt B Pockros P Terg R Shouval D van Hoek B Weiland O Van Heeswijk R De Meyer S Luo D Boogaerts G Polo R Picchio G Beumont M REALIZE Study Team | 2011 | N Engl J Med2011，364，25： | 1 |
| 3 | The Chlamydomonas genome reveals the evolution of key animal and plant functions 显示文摘 | Merchant S S Prochnik S E Vallon O Harris E H Karpowicz S J Witman G B Terry A Salamov A Fritz-Laylin L K Marechal- Drouard L Marshall W F Qu L H Nelson D R Sanderfoot A A Spalding M H Kapitonov V V Ren Q Ferris P Lindquist E Shapiro H Lucas S M Grimwood J Schmutz J Cardol P Cerutti H Chanfreau G Chen C L Cognat V Croft M T Dent R Dutcher S Fernandez E Fukuzawa H Gonzalez-Ballester D Gonzalez-Halphen D Hallmann A Hanikenne M Hippler M Inwood W Jabbari K Kalanon M Kuras R Lefebvre P A Lemaire S D Lobanov A V Lohr M Manuell A Meier I Mets L Mittag M Mittelmeier T Moroney J V Moseley J Napoli C Nedelcu A M Niyogi K Novoselov S V Paulsen I T Pazour G Purton S Ral J P Riano-Pachon D M Riekhof W Rymarquis L Schroda M Stern D Umen J Willows R Wilson N Zimmer S LAllmer J Balk J Bisova K Chen C J Elias M Gendler K Hauser C Lamb M R Ledford H Long J C Minagawa J Page M D Pan J Pootakham W Roje S Rose A Stahlberg E Terauchi A M Yang P Ball S Bowler C Dieckmann C L GIadyshev V N Green P Jorgensen R Mayfield S Mueller-Roeber B Rajamani S Sayre R T Brokstein P Dubchak I Goodstein D Hornick L Huang Y W Jhaveri J Luo Y Martinez D Ngau W C Otillar B Poliakov A Porter A Szajkowski L Werner G Zhou K Grigoriev I V Rokhsar D S Grossman A R | 2007 | Science2007，318，5848： | 1 |
| 4 | Variability and climatology of pwv from global 13-year GPS observations显示文摘 | JIN SH G LUO O F | 2009 | IEEE Geoscience and Rremote Sensing2009，47，1： | 1 |
| 5 | Hydrogen gener- ation from liquid reforming of glycerin over Ni -Co bime- tallic catalyst 显示文摘 | Luo N J Yang K O Cao F H Xiao T C | 2010 | International Journal of Hydrogen En- ergy2010，34，： | 1 |
| 6 | Telaprevir for retreatment of HCV infection显示文摘 | Zeuzem S Andreone P Pol S Lawitz E Diago M Roberts S Focaccia R Younossi Z Foster G R Horban A Ferenci P Nevens F Müllhaupt B Pockros P Terg R Shouval D Hoek B Weiland O Heeswijk R Meyer S Luo D Boogaerts G Polo R Picchio G Beumont M | 2011 | N Engl J Med2011，364，25： | 1 |
| 7 | The draft genome of sweet orange (Citrus sinensis)显示文摘 | Xu Q Chen L L Ruan X Chen D Zhu A Chen C Bertrand D Jiao W B Hao B H Lyon M P Chen J Gao S Xing F Lan H Chang J W Ge X Lei Y Hu Q Miao Y Wang L Xiao S Biswas M K Zeng W Guo F Cao H Yang X Xu X W Cheng Y J Xu J Liu J H Luo O J Tang Z Guo W W Kuang H Zhang | | 0，，： | 1 |
| 8 | Variability and Climatology of pwv From Global 13-Year GPS Observations显示文摘 | Shuanggen Jin Luo O F | | 0，，1： | 1 |
| 9 | Electron transfer at electrodes through conjugated 'molecular wire' bridges显示文摘 | CREAGER S YU C J BAMDAD C O'CONNOR S MACLEAN T LAM E CHONG Y OLSEN G T LUO J GOZIN M KAYYEM J F | | 0，，05： | 1 |
| 10 | Aggregation-induced emission of 1-methyl-1, 2, 3, 4, 5 pentaphenylsilole 显示文摘 | Luo J D Xie Z L Lain J W Y Cheng L Chen H Y Qiu C F Kwok H S Zhan X W Liu Y O Zhu D B Tang B Z | 2001 | Chemical Communications2001，，： | 1 |
| 11 | GPS observations of the ionospheric F2-1ayer behavior during the 20th November 2003 geomagnetic storm over South Korea 显示文摘 | JIN Shuang-gen LUO O F Park P | 2008 | Journal of Geodesy2008，82，12： | 1 |
| 12 | GPS Obserwltions of the Ionospheric F2 layer Behavior during the 20th NovemSer 2003 Geomagnetic Storm over South Korea显示文摘 | JIN S G LUO O F PARK P | 2008 | Journal ofGeodesy2008，82，12： | 1 |
| 13 | Simulation and experi- mental study of remote field eddy current testing on flat con- ductive plate显示文摘 | Wang H T Luo O F Wang X | 2010 | International journal of applied electromag- netics and mechanics2010，33，： | 1 |
| 14 | Role of transcription factors Brn-3,1 and Brn-3,2 in auditory and visual system development显示文摘 | Erkman L McEvilly RJ Luo L Ryan AK Hooshmand F O'Connell SM Keithley EM Rapaport DH Ryan AF Rosenfeld MG | | 0，，： | 1 |
| 15 | GPS observations of the i- onospheric F2-layer behavior during the 20th November 2003 geo- magnetic storm over South Korea显示文摘 | JIN SHUANGGEN LUO O F PARK P | 2008 | Journal of Geodesy2008，82，12： | 1 |
| 16 | Definition of tumor- associated antigens in hepatocellular carcinoma显示文摘 | Stenner-Liewen F Luo G Sahin U Tureci O | 2000 | Cancer Epidemiol Biomarkers Prev2000，9，： | 1 |
| 17 | GPS Observations of the Ionospheric F2-layer Behavior during the 20th November,2003 Geomagnetic Storm over South Korea显示文摘 | JIN Shuanggen LUO O F PARK P | 2008 | Journal of Geodesy2008，82，12： | 1 |
| 18 | Decline in subarachnoid haemorrhage volumes associated with the first wave of the COVID- 19 pandemic显示文摘Background During the COVID-19 pandemic,decreased volumes of stroke admissions and mechanical thrombectomy were reported.The study’s objective was to examine whether subarachnoid haemorrhage(SAH)hospitalisations and ruptured aneurysm coiling interventions demonstrated similar declines.Methods We conducted a cross-sectional,retrospective,observational study across 6 continents,37 countries and 140 comprehensive stroke centres.Patients with the diagnosis of SAH,aneurysmal SAH,ruptured aneurysm coiling interventions and COVID-19 were identified by prospective aneurysm databases or by International Classification of Diseases,10th Revision,codes.The 3-month cumulative volume,monthly volumes for SAH hospitalisations and ruptured aneurysm coiling procedures were compared for the period before(1 year and immediately before)and during the pandemic,defined as 1 March-31 May 2020.The prior 1-year control period(1 March-31 May 2019)was obtained to account for seasonal variation.Findings There was a significant decline in SAH hospitalisations,with 2044 admissions in the 3 months immediately before and 1585 admissions during the pandemic,representing a relative decline of 22.5%(95%CI−24.3%to−20.7%,p<0.0001).Embolisation of ruptured aneurysms declined with 1170-1035 procedures,respectively,representing an 11.5%(95%CI−13.5%to−9.8%,p=0.002)relative drop.Subgroup analysis was noted for aneurysmal SAH hospitalisation decline from 834 to 626 hospitalisations,a 24.9%relative decline(95%CI−28.0%to−22.1%,p<0.0001).A relative increase in ruptured aneurysm coiling was noted in low coiling volume hospitals of 41.1%(95%CI 32.3%to 50.6%,p=0.008)despite a decrease in SAH admissions in this tertile.Interpretation There was a relative decrease in the volume of SAH hospitalisations,aneurysmal SAH hospitalisations and ruptured aneurysm embolisations during the COVID-19 pandemic.These findings in SAH are consistent with a decrease in other emergencies,such as stroke and myocardial infarction. | Thanh N Nguyen Diogo C Haussen Muhammad M Qureshi Hiroshi Yamagami Toshiyuki Fujinaka Ossama Y Mansour Mohamad Abdalkader Michael Frankel Zhongming Qiu Allan Taylor Pedro Lylyk Omer F Eker Laura Mechtouff Michel Piotin Fabricio Oliveira Lima Francisco Mont'Alverne Wazim Izzath Nobuyuki Sakai Mahmoud Mohammaden Alhamza R Al-Bayati Leonardo Renieri Salvatore Mangiafico David Ozretic Vanessa Chalumeau Saima Ahmad Umair Rashid Syed Irteza Hussain Seby John Emma Griffin John Thornton Jose Antonio Fiorot Rodrigo Rivera Nadia Hammami Anna M Cervantes-Arslanian Hormuzdiyar H Dasenbrock Huynh Le Vu Viet Quy Nguyen Steven Hetts Romain Bourcier Romain Guile Melanie Walker Malveeka Sharma Don Frei Pascal Jabbour Nabeel Herial Fawaz Al-Mufti Atilla Ozcan Ozdemir Ozlem Aykac Dheeraj Gandhi Chandril Chugh Charles Matouk Pascale Lavoie Randall Edgell Andre Beer-Furlan Michael Chen Monika Killer-Oberpfalzer Vitor Mendes Pereira Patrick Nicholson Vikram Huded Nobuyuki Ohara Daisuke Watanabe Dong Hun Shin Pedro SC Magalhaes Raghid Kikano Santiago Ortega-Gutierrez Mudassir Farooqui Amal Abou-Hamden Tatsuo Amano Ryoo Yamamoto Adrienne Weeks Elena A Cora Rotem Sivan-Hoffmann Roberto Crosa Markus Möhlenbruch Simon Nagel Hosam Al-Jehani Sunil A Sheth Victor S Lopez Rivera James E Siegler Achmad Fidaus Sani Ajit S Puri Anna Luisa Kuhn Gianmarco Bernava Paolo Machi Daniel G Abud Octavio M Pontes-Neto Ajay K Wakhloo Barbara Voetsch Eytan Raz Shadi Yaghi Brijesh P Mehta Naoto Kimura Mamoru Murakami Jin Soo Lee Ji Man Hong Robert Fahed Gregory Walker Eiji Hagashi Steve M Cordina Hong Gee Roh Ken Wong Juan F Arenillas Mario Martinez-Galdamez Jordi Blasco Alejandro Rodriguez Vasquez Luisa Fonseca M Luis Silva Teddy Y Wu Simon John Alex Brehm Marios Psychogios William J Mack Matthew Tenser Tatemi Todaka Miki Fujimura Roberta Novakovic Jun Deguchi Yuri Sugiura Hiroshi Tokimura Rakesh Khatri Michael Kelly Lissa Peeling Yuichi Murayama Hugh Stephen Winters Johnny Wong Mohamed Teleb Jeremy Payne Hiroki Fukuda Kosuke Miyake Junsuke Shimbo Yusuke Sugimura Masaaki Uno Yohei Takenobu Yuji Matsumaru Satoshi Yamada Ryuhei Kono Takuya Kanamaru Masafumi Morimoto Junichi Iida Vasu Saini Dileep Yavagal Saif Bushnaq Wenguo Huang Italo Linfante Jawad Kirmani David S Liebeskind Viktor Szeder Ruchir Shah Thomas G Devlin Lee Birnbaum Jun Luo Anchalee Churojana Hesham E Masoud Carlos Ynigo Lopez Brendan Steinfort Alice Ma Ameer E Hassan Amal Al Hashmi Mollie McDermott Maxim Mokin Alex Chebl Odysseas Kargiotis Georgios Tsivgoulis Jane G Morris Clifford J Eskey Jesse Thon Leticia Rebello Dorothea Altschul Oriana Cornett Varsha Singh Jeyaraj Pandian Anirudh Kulkarni Pablo M Lavados Veronica V Olavarria Kenichi Todo Yuki Yamamoto Gisele Sampaio Silva Serdar Geyik Jasmine Johann Sumeet Multani Artem Kaliaev Kazutaka Sonoda Hiroyuki Hashimoto Adel Alhazzani David Y Chung Stephan A Mayer Johanna T Fifi Michael D Hill Hao Zhang Zhengzhou Yuan Xianjin Shang Alicia C Castonguay Rishi Gupta Tudor G Jovin Jean Raymond Osama O Zaidat Raul G Nogueira SVIN COVID-19 Registry,the Middle East North Africa Stroke and Interventional Neurotherapies Organization(MENA-SINO),Japanese Society of Vascular and Interventional Neurology Society(JVIN) | 2021 | Stroke & Vascular Neurology2021，6，4： | 0 |
| 19 | Trends and risk factors for opioid administration for non-emergent lower back pain显示文摘BACKGROUND Non-emergent low-back pain(LBP)is one of the most prevalent presenting complaints to the emergency department(ED)and has been shown to contribute to overcrowding in the ED as well as diverting attention away from more serious complaints.There has been an increasing focus in current literature regarding ED admission and opioid prescriptions for general complaints of pain,however,there is limited data concerning the trends over the last decade in ED admissions for non-emergent LBP as well as any subsequent opioid prescriptions by the ED for this complaint.AIM To determine trends in non-emergent ED visits for back pain;annual trends in opioid administration for patients presenting to the ED for back pain;and factors associated with receiving an opioid-based medication for non-emergent LBP in the ED METHODS Patients presenting to the ED for non-emergent LBP from 2010 to 2017 were retrospectively identified from the National Hospital Ambulatory Medical Care Survey database.The“year”variable was transformed to two-year intervals,and a weighted survey analysis was conducted utilizing the weighted variables to generate incidence estimates.Bivariate statistics were used to assess differences in count data,and logistic regression was performed to identify factors associated with patients being discharged from the ED with narcotics.Statistical significance was set to a P value of 0.05.RESULTS Out of a total of 41658475 total ED visits,3.8%(7726)met our inclusion and exclusion criteria.There was a decrease in the rates of non-emergent back pain to the ED from 4.05%of all cases during 2010 and 2011 to 3.56%during 2016 and 2017.The most common opioids prescribed over the period included hydrocodone-based medications(49.1%)and tramadol-based medications(16.9),with the combination of all other opioid types contributing to 35.7%of total opioids prescribed.Factors significantly associated with being prescribed narcotics included age over 43.84-years-old,higher income,private insurance,the obtainment of radiographic imaging in the ED,and region of the United States(all,P<0.05).Emergency departments located in the Midwest[odds ratio(OR):2.42,P<0.001],South(OR:2.35,<0.001),and West(OR:2.57,P<0.001)were more likely to prescribe opioid-based medications for non-emergent LBP compared to EDs in the Northeast.CONCLUSION From 2010 to 2017,there was a significant decrease in the number of nonemergent LBP ED visits,as well as a decrease in opioids prescribed at these visits.These findings may be attributed to the increased focus and regulatory guidelines on opioid prescription practices at both the federal and state levels.Since nonemergent LBP is still a highly common ED presentation,conclusions drawn from opioid prescription practices within this cohort is necessary for limiting unnecessary ED opioid prescriptions. | Chukwuweike U Gwam Ahmed K Emara Noor Chughtai Sameer Javed T David Luo Kevin Y Wang Morad Chughtai Tadhg O'Gara Johannes F Plate | 2021 | World Journal of Orthopedics2021，12，9： | 0 |
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