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| 1 | PI 3-kinase pathway is responsible for antiapoptotic effects of atrial natriuretic peptide in rat liver transplantation显示文摘AIM:To investigate the in vivo effect of atrial natriureticpeptide(ANP)and its signaling pathway during ortho-topic rat liver transplantation.METHODS:Rats were infused with NaCl,ANP(5 μg/kg),wortmannin(WM,16 μg/kg),or a combination ofboth for 20 min.Livers were stored in UW solution(4°C)for 24 h,transplanted and reperfused.Apoptosis wasexamined by caspase-3 activity and TUNEL staining.Phosphorylation of Akt and Bad was visualized by West-ern blotting and phospho-Akt-localization by confocalmicroscopy.RESULTS:ANP-pretreatment decreased caspase-3activity and TUNEL-positive cells after cold ischemia,indicating antiapoptotic effects of ANP in vivo.The an-tiapoptotic signaling of ANP was most likely caused byphosphorylation of Akt and Bad,since pretreatment withPI 3-kinase inhibitor WM abrogated the ANP-inducedreduction of caspase-3 activity.Interestingly,analysis ofliver tissue by confocal microscopy showed translocationof phosphorylated Akt to the plasma membrane of hepa-tocytes evoked by ANP.CONCLUSION:ANP activates the PI-3-kinase pathwayin the liver in vivo leading to phosphorylation of Bad, an event triggering antiapoptotic signaling cascade inischemic liver. | Uwe Grutzner Melanie Keller Michael Bach Alexandra K Kiemer Herbert Meissner Manfred Bilzer Stefan Zahler Alexander L Gerbes Angelika M Vollmar | 2006 | World Journal of Gastroenterology2006，12，7： | 3 |
| 2 | Examining effective use of data sources and modeling algorithms for improving biomass estimation in a moist tropical forest of the Brazilian Amazon显示文摘Previous research has explored the potential to integrate lidar and optical data in aboveground biomass(AGB)estimation,but how different data sources,vegetation types,and modeling algorithms influence AGB estimation is poorly understood.This research conducts a comparative analysis of different data sources and modeling approaches in improving AGB estimation.RapidEye-based spectral responses and textures,lidar-derived metrics,and their combination were used to develop AGB estimation models.The results indicated that(1)overall,RapidEye data are not suitable for AGB estimation,but when AGB falls within 50–150 Mg/ha,support vector regression based on stratification of vegetation types provided good AGB estimation;(2)Lidar data provided stable and better estimations than RapidEye data;and stratification of vegetation types cannot improve estimation;(3)The combination of lidar and RapidEye data cannot provide better performance than lidar data alone;(4)AGB ranges affect the selection of the best AGB models,and a combination of different estimation results from the best model for each AGB range can improve AGB estimation;(5)This research implies that an optimal procedure for AGB estimation for a specific study exists,depending on the careful selection of data sources,modeling algorithms,forest types,and AGB ranges. | Yunyun Feng Dengsheng Lu Qi Chena Michael Keller Emilio Moran Maiza Nara dos-Santos Edson Luis Bolfe Mateus Batistella | 2017 | International Journal of Digital Earth2017，10，10： | 2 |
| 3 | Functional response and predation of Nabis kinbergii (Hemiptera. Nabidae) to Plutella xylostella (Lepidoptera. Plutellidae)显示文摘成年 Nabis kinbergii 的功能的反应(半翅类:Nabidae ) 到有菱形斑纹的蛾 Plutella xylostella 的密度(鳞翅目:Plutellidae ) 在实验室条件下面被调查。Holling' s (1959 ) 类型Ⅱ模型被发现是一好为这个食肉动物的观察功能的反应合适。P 的数字。消费的 xylostella 从 15 ℃与温度增加了到 35 ℃。杀死的猎物的最大的数字向前在 35 ℃被观察,与 10.3 和 8.3 的一般水准中间形态幼虫由 N 的成年女性和男性消费了。kinbergii 分别地。N 的捕食。P 上的 kinbergii。xylostella 与连续最不成熟的年龄增加了。当猎物的身体尺寸增加了,食肉动物消费的猎物的数字减少了。131 个鸡蛋的 Anaverage 或 P 的 95 幼虫。xylostella 被女成年人的一个单身者在 24 ℃在 24hours 打死。P 的蛹。xylostella 被观察被第五个中间形态美女和成年人 N 吃。在数字的 kinbergii 不到 0.7 蛹的一般水准每在 24 小时 at24 ℃的食肉动物。由 N 的捕食偏爱。kinbergii 也被调查。P 的数字。xylostella andMyzus persicae 由女 N 杀死了。kinbergii 不是显著地不同的,但是男性们显著地杀死了更多的 P。xylostella 比 M。persicae。P 的鸡蛋和幼虫。xylostella 在一样的喂竞技场 Pieris rapae 比那些在显著地更大的数字被打死。 | JUN MA YOU-ZHI LI MICHAEL KELLER SHUN-XIANG REN | 2005 | Insect Science2005，12，4： | 2 |
| 4 | Human adipose tissue-derived mesenchymal stem cells differentiate into insulin, somatostatin, and glucagon expressing cells显示文摘 | Katharina Timper Dalma Seboek Michael Eberhardt Philippe Linscheid Mirjam Christ-Crain Ulrich Keller Beat Müller Henryk Zulewski | 2006 | Biochemical and Biophysical Research Communications2006，，4： | 2 |
| 5 | Fertilizer-induced nitric oxide emissions from agricultural soils显示文摘 | Edzo Veldkamp Michael Keller | | Nutrient Cycling in Agroecosystems (-)0，，： | 1 |
| 6 | Nitrogen Oxide Fluxes and Nitrogen Cycling during Postagricultural Succession and Forest Fertilization in the Humid Tropics显示文摘 | Heather Erickson Michael Keller Eric A. Davidson | 2001 | Ecosystems2001，，1： | 1 |
| 7 | Basic Epidemiology of Fractures of the Upper and Lower Limb among Americans over 65 Years of Age显示文摘 | John A. Baron Margaret Karagas Jane Barrett Wayne Kniffin David Malenka Michael Mayor Robert B. Keller | 1996 | Epidemiology1996，，6： | 1 |
| 8 | A self-healing poly ( dimethylsiloxane ) elastomer 显示文摘 | KELLER Michael Wade WHITE Scott Ray SOTTOS Nancy R | 2007 | Advanced Functional Materials2007，17，14： | 1 |
| 9 | Human adipose tissue-derived mesenchymal stem cells differentiate into insulin, somatostatin, and glucagon expressing cells显示文摘 | Katharina Timper Dalma Seboek Michael Eberhardt Philippe Linscheid Mirjam Christ-Crain Ulrich Keller Beat Müller Henryk Zulewski | 2006 | Biochemical and Biophysical Research Communications2006，，4： | 1 |
| 10 | A Fuzzy K-Nearest Neighbor algorithm显示文摘 | JAMES M KELLER MICHAEL R GRAY JAMES A GIVENS | 1985 | IEEE Transactions on Systems Man Cybernetics1985，15，4： | 1 |
| 11 | Immunodominant peptides from conserved influenza proteins – A tool for more efficient vaccination in the elderly?显示文摘 | Giovanni Almanzar Dietmar Herndler-Brandstetter Sandra Vega Chaparro Brigitte Jenewein Michael Keller Beatrix Grubeck-Loebenstein | 2007 | Wiener Medizinische Wochenschrift2007，，： | 1 |
| 12 | Estimates of forest canopy height and aboveground biomass using the Geoscience Laser Altimeter System显示文摘 | Lefsky Michael A Harding D J Michael Keller | 2005 | Geophys Res Lett2005，32，： | 1 |
| 13 | AmazonForest Structure from IKONOS Satellite Data and the AutomatedCharacterization of Forest Canopy Properties显示文摘 | Michael Palace Michael Keller Gregory P Asner | 2008 | Biotropica2008，40，2： | 1 |
| 14 | Effects of tropical deforestation on global and regional atmospheric chemistry显示文摘 | Michael Keller Daniel J. Jacob Steven C. Wofsy Robert C. Harriss | 1991 | Climatic Change (-)1991，，1： | 1 |
| 15 | Structural health management technologies for inflatable/deployable structures: Integrating sensing and self-healing显示文摘 | Erik J. Brandon Max Vozoff Elizabeth A. Kolawa George F. Studor Frankel Lyons Michael W. Keller Brett Beiermann Scott R. White Nancy R. Sottos Mark A. Curry David L. Banks Robert Brocato Lisong Zhou Soyoun Jung Thomas N. Jackson Kevin Champaigne | 2010 | Acta Astronautica2010，，7： | 1 |
| 16 | Celecoxib, a Selective Cyclooxygenase-2 Inhibitor, Decreases Monocyte Chemoattractant Protein-1 Expression and Neointimal Hyperplasia in the Rabbit Atherosclerotic Balloon Injury Model显示文摘 | Kai Wang Khaldoun Tarakji Zhongmin Zhou Ming Zhang Farhad Forudi Xiaorong Zhou Alane T. Koki Mark E. Smith Bradley T. Keller Eric J. Topol A. Michael Lincoff Marc S. Penn | 2005 | Journal of Cardiovascular Pharmacology2005，，1： | 1 |
| 17 | Large-Size Honeycomb-Shaped and Iris-Like Liquid Crystal Elastomer Actuators显示文摘Nature is providing inspiration for researchers to mimic its functions or existing structures,which could remarkably promote the development of new materials.Here,a large-size honeycomb-shaped liquid crystal elastomer(LCE)actuator with LC orientation along the height of the honeycomb shape is built by combining magnetic field alignment and soft lithography technology.This homeotropic alignment allowed the height contraction of honeycomb and pore size expansion of hexagons in a reversible manner upon temperature variation.Therefore,this LCE actuator can be used as a structure for temperature-gated separation of particles.Another example is an iris-like LCE actuator,which has the capability of adjusting its aperture size with a temperature variation.Our approach provides a simple way to design customizable sophisticated LCE actuators for various potential applications. | Bin Ni Gaoyu Liu Mengxue Zhang Patrick Keller Michael Tatoulian Min-Hui Li | 2022 | CCS Chemistry2022，4，3： | 1 |
| 18 | Increasing the value of weather-related warnings显示文摘Despite advances in forecasting and emergency preparedness, weather related disasters continue to cost many lives, to displace populations and to cause wide-spread damage. Therefore, High Impact Weather Project (HIWeather), a 10-year research project (http://gffzz72c37a797ca44d97sc0w00nvqbk9u6w0b.ffgz.tsg.suse.edu.cn/en/resources/buHetin/hiweather-10-yearresearch- project), was established in 2016 by WM0 (World Meteorology Organization) WWRP (World Weather Research Program: http://gffzz74e393fd09b145d8sc0w00nvqbk9u6w0b.ffgz.tsg.suse.edu.cn/pages/prog/arep/wwrp/new/wwrp_new_en. html). HIWeather aimed at achieving dramatic improvements in the effectiveness of weather-related hazard warnings, following recent advancement in numerical weather prediction at km-scale and in disaster risk reduction. The implementation plan was developed under the concept of warning chain, which comprises all components and the connections between to a successful weather-hazards warning: observations, weather forecast, hazard forecast, impact forecast, the generation of warnings and decision making (Fig. 1). A successful warning relies on information produced by the meteorological and related physical sciences, thus its effectiveness of delivery depends on applications of social, behavioral and economic sciences. The workshop of WM0 High Impact Weather Project was held in Beijing during 20-22 November of 2018, attracted a diverse and interdisciplinary group of over 70 scientists from 25 countries in the broad field of physical and social science, during which all elements of the warning chain were discussed critically. | Qinghong Zhang Liye Li Beth Ebert Brian Golding David Johnston Brian Mills Shannon Panchuk Sally Potter Michael Riemer Juanzhen Sun Andrea Taylor Sarah Jones Paolo Ruti Julia Keller | 2019 | Science Bulletin2019，64，10： | 1 |
| 19 | The effects of brand name suggestiveness on advertising recall 显示文摘 | Keller K L Susan E H Michael J H | 1998 | Journal of Marketing1998，62，1： | 1 |
| 20 | Effects of seed provenance on germination of herbs for agricultural compensation sites 显示文摘 | MICHAEL KELLER J K | 1999 | Agriculture Ecosystems & Environment1999，72，1： | 1 |
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