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| 1 | Efficacy and safety of a novel anti-HER2 therapeutic antibody RC48 in patients with HER2-overexpressing,locally advanced or metastatic gastric or gastroesophageal junction cancer:a single-arm phase II study显示文摘Background:Current treatment options for human epidermal growth factor receptor 2(HER2)-overexpressing gastric cancer at third-line have shown limited clinical benefit.Further,there is no specific treatment for HER2 immunohistochemistry(IHC)2+and fluorescence in-situ hybridization-negative patients.Here,we report the efficacy and safety of a novel anti-HER2 antibody RC48 for patients with HER2-overexpressing,advanced gastric or gastroesophageal junction cancer.Methods:Patients with HER2-overexpressing(IHC 2+or 3+),locally advanced or metastatic gastric or gastroesophageal junction cancer who were under at least second-line therapy were eligible and received RC482.5 mg/kg alone every 2 weeks.The primary endpoint was the objective response rate(ORR)assessed by an independent review committee.Secondary endpoints included progressionfree survival(PFS),overall survival(OS),duration of response,time to progression,disease control rate,and safety.Results:Of 179 patients screened,125 were eligible and received RC48 treatment.The ORR was 24.8%(95%confidence interval[CI]:17.5%-33.3%).The median PFS and OS were 4.1 months(95%CI:3.7-4.9 months)and 7.9 months(95%CI:6.7-9.9 months),respectively.The most frequently reported adverse events were decreased white blood cell count(53.6%),asthenia(53.6%),hair loss(53.6%),decreased neutrophil count(52.0%),anemia(49.6%),and increased aspartate aminotransferase level(43.2%).Serious adverse events(SAEs)occurred in 45(36.0%)patients,and RC48-related SAEs were mainly decreased neutrophil count(3.2%).Seven patients had adverse events that led to death were not RC48-related.Conclusions:RC48 showed promising activity with manageable safety,suggesting potential application in patients with HER2-overexpressing,advanced gastric or gastroesophageal junction cancer who have previously received at least two lines of chemotherapy. | Zhi Peng Tianshu Liu Jia Wei Airong Wang Yifu He Liuzhong Yang Xizhi Zhang Nanfeng Fan Suxia Luo Zhen Li Kangsheng Gu Jianwei Lu Jianming Xu Qingxia Fan Ruihua Xu Liangming Zhang Enxiao Li Yuping Sun Guohua Yu Chunmei Bai Yong Liu Jiangzheng Zeng Jieer Ying Xinjun Liang Nong Xu Chao Gao Yongqian Shu Dong Ma Guanghai Dai Shengmian Li Ting Deng Yuehong Cui Jianmin Fang Yi Ba Lin Shen | 2021 | Cancer Communications2021，41，11： | 29 |
| 2 | Mapping Heterotic Loci for Yield and Agronomic Traits Using Chromosome Segment Introgression Lines in Cotton显示文摘在现在的学习,一套染色体片断基因渗入排队(CSIL ) 使用 Gossypium hirsutum L。TM-1 作为接受者父母和 G。施主父母被用来为种间的混血儿探索杂种优势的基因基础的 barbadense Hai7124。个别地从与两个父母一起交叉的 CSIL 导出的 F1 人口的二个集合被设置调查 heterotic loci (HL ) 和替换效果 loci (SL ) 。58 HL 和 39 SL 的一个总数在 3 年里被识别。一稳定的 HL, hLP-A4-3,能在所有 3 年里被检测。三 HL, hBS-A8-1, hLP-D6-1,和 hSI-D7-11,能在 2 年里被检测。四 SL, sBS-D7-1, sLP-A8-1, sLP-D7-1,和 sLP-D12-1,能在 2 年里被检测。HL 和 SL 趋于在有靠近的位置的一些 HL 富有的染色体片断分布式。与在以前的研究检测的 QTL 相比, HL 与 QTL 显示出很少重叠,显示特点显型和杂种优势可能被 loci 的不同集合控制。基因效果的所有三种形式(部分 -- ,完整 -- ,在主导上) 被识别,当在主导上的效果做了主要贡献到杂种优势时。这些结果可以帮助为在棉花澄清杂种优势的遗传机制打了基础。 | Xian Guo Yuping Guo Jun Ma Fang Wang Mizhen Sun Lijuan Gui Jiajia Zhou Xianliang Song Xuezhen Sun Tianzhen Zhang | 2013 | Journal of Integrative Plant Biology2013，55，8： | 13 |
| 3 | Effect of extrusion speed on microstructure and mechanical properties of the Mg-Ca binary alloy显示文摘This work reported the effect of extrusion speeds on the microstructures and mechanical properties of Mg-Ca binary alloy.The results showed that yield strength of the as-extruded Mg-1.2wt.%Ca alloys decrease from∼360MPa to∼258MPa as the ram speed increases from 0.4mm/s to 2.4 mm/s,and the elongation increases from∼3.9%to∼12.2%.The microstructure changes from bimodal grain feature to the complete dynamical recrystallization(DRX)with increase of the extrusion speed.The ultrafine DRXed grains in size of∼0.85μm,the numerous nano-Mg_(2)Ca particles dispersing along the grain boundaries and interiors,as well as the high density of residual dislocations,should account for the high strength.It is believed that the high degree of dynamic recrystallization and the resulting texture randomization play the critical roles in the ductility enhancement of the high-speed extruded Mg alloys. | Jingren Li Aiyue Zhang Hucheng Pan Yuping Ren Zhuoran Zeng Qiuyan Huang Changlin Yang Lifeng Ma Gaowu Qin | 2021 | Journal of Magnesium and Alloys2021，9，4： | 9 |
| 4 | OsSPL18 controls grain weight and grain number in rice显示文摘Grain weight and grain number are two important traits directly determining grain yield in rice. To date,a lot of genes related to grain weight and grain number have been identified; however, the regulatory mechanism underlying these genes remains largely unknown. In this study, we studied the biological function of OsSPL18 during grain and panicle development in rice. Knockout (KO) mutants of OsSPL18exhibited reduced grain width and thickness, panicle length and grain number, but increased tiller number. Cytological analysis showed that OsSPL18 regulates the development of spikelet hulls by affecting cell proliferation. qRT-PCR and GUS staining analyses showed that OsSPL18 was highly expressed in developing young panicles and young spikelet hulls, in agreement with its function in regulating grain and panicle development. Transcriptional activation experiments indicated that OsSPL18is a functional transcription factor with activation domains in both the N-terminus and C-terminus, and both activation domains are indispensable for its biological functions. Quantitative expression analysis showed that DEP1, a major grain number regulator, was significantly down-regulated in OsSPL18 KO lines.Both yeast one-hybrid and dual-luciferase (LUC) assays showed that OsSPL18 could bind to the DEP1promoter, suggesting that OsSPL18 regulates panicle development by positively regulating the expression of DEP1. Sequence analysis showed that OsSPL18 contains the OsmiR156k complementary sequence in the third exon; 5?RLM-RACE experiments indicated that OsSPL18 could be cleaved by OsmiR156k. Taken together, our results uncovered a new OsmiR156k-OsSPL18-DEP1 pathway regulating grain number in rice. | Hua Yuan Peng Qin Li Hu Shijie Zhan Shifu Wang Peng Gao Jing Li Mengya Jin Zhengyan Xu Qiang Gao Anping Du Bin Tu Weilan Chen Bingtian Ma Yuping Wang Shigui Li | 2019 | Journal of Genetics and Genomics2019，46，1： | 8 |
| 5 | Detection of serum IgM and IgG for COVID-19 diagnosis显示文摘Dear Editor,Infection with the novel coronavirus(SARS-CoV-2,which is the virus responsible for the coronavirus disease 2019(COVID-19))was first reported in Wuhan,China on December 31,2019.The outbreak of COVID-19 remains ongoing and was linked to more than 80,000 infected patients and more than 3,000 deaths in China as of March 7,2020(Holshue et al.,2020). | Ling Zhong Junlan Chuan Bo Gong Ping Shuai Yu Zhou Yi Zhang Zhilin Jiang Dingding Zhang Xiaoqi Liu Shi Ma Yi Huang He Lin Qingwei Wang Lulin Huang Dan Jiang Fang Hao Juan Tang Chunqi Zheng Hua Yu Zhibin Wang Qi Jiang Tao Zeng Mei Luo Fanwei Zeng Fanxin Zeng Jianghai Liu Junxi Tian Yu Xu Tengxiang Long Kaiju Xu Xingxiang Yang Yuping Liu Yi Shi Li Jiang Zhenglin Yang | 2020 | Science China(Life Sciences)2020，63，5： | 8 |
| 6 | Dynamic changes in soil chemical properties and microbial community structure in response to different nitrogen fertilizers in an acidified celery soil显示文摘To determine the effects of different kinds of nitrogen fertilizer,especially high-efficiency slowrelease fertilizers,on soil pH,nitrogen(N)and microbial community structures in an acidic celery soil,four treatments(CK,no N fertilizer;NR,urea;PE,calcium cyanamide fertilizer;and SK,controlled-release N fertilizer)were applied,and soil pH,total soil N,inorganic N,and soil microbial biomass C were analyzed.Phospholipid fatty acids(PLFAs)were extracted and detected using the MIDI Sherlock microbial identification system.The PE treatment significantly improved soil pH,from 4.80 to>6.00,during the whole growth period of the celery,and resulted in the highest celery yield among the four treatments.After 14 d application of calcium cyanamide,the soil nitrate content significantly decreased,but the ammonium content significantly increased.The PE treatment also significantly increased soil microbial biomass C during the whole celery growth period.Canonical variate analysis of the PLFA data indicated that the soil microbial community structure in the CK treatment was significantly different from those in the N applied treatments after 49 d fertilization.However,there was a significant difference(P<0.05)in soil microbial community structure between the PE treatment and the other three treatments at the end of the experiment.Calcium cyanamide is a good choice for farmers to use on acidic celery land because it supplies sufficient N,and increases soil pH,microbial biomass and the yield of celery. | Yuping Wu Jiangxing Wu Yongjun Ma Ying Lian Hui Sun Danchao Xie Yaying Li Philip C.Brookes Huaiying Yao | 2019 | Soil Ecology Letters2019，1，3： | 7 |
| 7 | Applications of gold nanorods in biomedical imaging and related fields显示文摘Gold nanorods (GNRs) have great potential widespread applications in biomedical imaging, drug delivery and photothermal therapy due to unique surface plasmon resonance (SPR) ranging from visible to near infrared (NIR) region, facile synthesis and easy functionalization. In this review, the recent progress of GNRs in bioimaging, drug delivery, photothermal therapy and theranostics is summarized and the recommendations for the future work on GNRs are also covered. | MA ZhiYa XIA HongXing LIU YuPing LIU Bo CHEN Wei ZHAO YuanDi | 2013 | Chinese Science Bulletin2013，58，21： | 6 |
| 8 | An experiment-library least-squares method on on-line coal element contents analysis显示文摘A new experiment-library least-squares(experiment-LLs) method used in the neutron inelastic-scattering and thermal-capture analysis(NITA) technique for on-line coal analysis was developed,which has significantly decreased the non-linear radiation effects.In this method,sixty samples with preset elemental contents were made,from whose experimental spectra twenty single-element spectrum libraries corresponding to twenty kinds of coal were built using the least-squares method.The spectrum of the unknown sample was analyzed based on these twenty libraries to estimate its element contents.With the initial estimated result,the procedure of developing library and analysis was iterated to build a new library with the closest element contents to the unknown sample.Hence the experiment-LLs method can reduce non-linear radiation effects.The experiment-LLs method was performed on an improved coal analysis system which was equipped with a long-life 14 MeV pulsed-neutron generator,a bulk BGO detector with a temperature controller,a moisture meter and coal-smoothing device.The precisions of this system for ash content,water content,volatile content and calorific value have reached 1.0wt%,0.5wt%,1.0wt%,350 kJ/kg,respectively. | WANG HuiDong LU JingBin LU YuPing YANG Dong MA KeYan YANG Kang LIU YuMin CHENG DaoWen | 2012 | Science China(Physics,Mechanics & Astronomy)2012，55，11： | 6 |
| 9 | Loss of Gn1a/OsCKX2 confers heavy-panicle rice with excellent lodging resistance显示文摘Significant achievements have been made in breeding programs for the heavy-panicle-type(HPT)rice(Oryza sativa) in Southwest China. The HPT varieties now exhibit excellent lodging resistance,allowing them to overcome the greater pressures caused by heavy panicles. However, the genetic mechanism of this lodging resistance remains elusive. Here, we isolated a major quantitative trait locus, Panicle Neck Diameter 1(PND1), andidentified the causal gene as GRAIN NUMBER 1 A/CYTOKININ OXIDASE 2(Gn1 A/Os CKX2). The null gn1 a allele from rice line R498(gn1 aR498) improved lodging resistance through increasing the culm diameter and promoting crown root development.Loss-of-function of Gn1 a/Os CKX2 led to cytokinin accumulation in the crown root tip and accelerated the development of adventitious roots. Gene pyramiding between the null gn1 aR498 allele with two gain-of-function alleles, STRONG CULM 2(SCM2)and SCM3, further improved lodging resistance.Moreover, Gn1 a/Os CKX2 had minimal influence on overall rice quality. Our research thus highlights the distinct genetic components of lodging resistance of HPT varieties and provides a strategy for tailormade crop improvement of both yield and lodging resistance in rice. | Bin Tu Zhang Tao Shiguang Wang Lei Zhou Ling Zheng Chun Zhang Xinzi Li Xiaoyu Zhang Junjie Yin Xiaobo Zhu Hua Yuan Ting Li Weilan Chen Peng Qin Bingtian Ma Yuping Wang Shigui Li | 2022 | Journal of Integrative Plant Biology2022，64，1： | 5 |
| 10 | Single-dose and multiple-dose pharmacokinetics of zaltoprofen after oral administration in healthy Chinese volunteers显示文摘Zaltoprofen, a propionic acid derivative of non-steroidal anti-inflammatory drugs, has strong inhibitory effects on actue and chronic inflammation. A randomized, dose-escalating study was conducted to evaluate the pharma-cokinetics of single and multiple oral doses of zaltoprofen in 12 healthy Chinese volunteers. Pharmacokinetics was determined from serial blood samples obtained up to 24 h after administration of a single dose of zaltoprofen at 80, 160 or 240 mg and after multiple doses of zaltqorofen at 80 mg 3 times daily. The C max and AUC 0-24 of zaltoprofen were found to be proportional to drug dose. Zaltoprofen was rapidly absorbed (t max =1.46±0.83 h) and cleared (t 1/2 =4.96±2.97 h). Pharmacokinetic parameters after multiple doses were similar to those after single doses. Zaltoprofen was well tolerated. These results support a tid regimen of zaltoprofen for the management of acute and chronic inflammation. | Lingjun Li Pengcheng Ma Yuping Cao Lei Tao Yue Tao | 2011 | The Journal of Biomedical Research2011，25，1： | 4 |
| 11 | Characterization and Fine Mapping of GLABROUS RICE 2 in Rice显示文摘Glabrous rice exhibits glabrous leaves and hulls because neither of these structures have trichomes on their surfaces.Glabrous rice varieties have become an important germplasm resource in the rice industry because they have considerable packaging efficiency and can reduce skin itching and dust during harvesting,drying,and packing(Shim et al.,2012;Zhang et al.,2012).Trichomes are ubiquitous in land plants and they originate from the expansion of the epidermal cell and then develop through growth,differentiation,or cell division to produce hair-like tissues that extend from epidermal | Yuping Wang Weilan Chen Peng Qin Yanyan Huang Bingtian Ma Xinhao Ouyang Xuewei Chen Shigui Li | 2013 | Journal of Genetics and Genomics2013，40，11： | 4 |
| 12 | Differentiation of mesenchymal stem cells into neuronal cells on fetal bovine acellular dermal matrix as a tissue engineered nerve scaffold显示文摘The purpose of this study was to assess fetal bovine acellular dermal matrix as a scaffold for supporting the differentiation of bone marrow mesenchymal stem cells into neural cells following induction with neural differentiation medium.We performed long-term,continuous observation of cell morphology,growth,differentiation,and neuronal development using several microscopy techniques in conjunction with immunohistochemistry.We examined specific neuronal proteins and Nissl bodies involved in the differentiation process in order to determine the neuronal differentiation of bone marrow mesenchymal stem cells.The results show that bone marrow mesenchymal stem cells that differentiate on fetal bovine acellular dermal matrix display neuronal morphology with unipolar and bi/multipolar neurite elongations that express neuronal-specific proteins,including βIII tubulin.The bone marrow mesenchymal stem cells grown on fetal bovine acellular dermal matrix and induced for long periods of time with neural differentiation medium differentiated into a multilayered neural network-like structure with long nerve fibers that was composed of several parallel microfibers and neuronal cells,forming a complete neural circuit with dendrite-dendrite to axon-dendrite to dendrite-axon synapses.In addition,growth cones with filopodia were observed using scanning electron microscopy.Paraffin sectioning showed differentiated bone marrow mesenchymal stem cells with the typical features of neuronal phenotype,such as a large,round nucleus and a cytoplasm full of Nissl bodies.The data suggest that the biological scaffold fetal bovine acellular dermal matrix is capable of supporting human bone marrow mesenchymal stem cell differentiation into functional neurons and the subsequent formation of tissue engineered nerve. | Yuping Feng Jiao Wang Shixin Ling Zhuo Li Mingsheng Li Qiongyi Li Zongren Ma Sijiu Yu | 2014 | Neural Regeneration Research2014，9，22： | 4 |
| 13 | Synthesis of three-dimensionally ordered porous perovskite type LaMnO_3 for Al-air battery显示文摘LaMnO_3 catalysts with three-dimensionally ordered holes perovskite structure were prepared via closepacked SiO_2 template synthesized by Stober-Frink method. SEM, XRD and BET were employed to characterize the microstructure, phases and specific surface area. CV method was used to the oxygen electrode beha-vior of catalysts. Diameter of the holes was about 330 nm, corresponding to the size of SiO_2 template. Full-cell discharge tests were performed on aluminum-air battery fabricated by porous LaMnO_3.Results showed that the discharge performance of porous LaMnO_3 were 1.54 V, 1.42 V and 1.24 V respectively when the discharge currents were set at 5 mA/cm^2,10 mA/cm^2 and 20 mA/cm^2, respectively, which were higher than that of LaMnO_3 prepared by coprecipitation method(1.33 V, 1.09 V, 0.63 V, respectively). | Fuwei Xiang Xiuhua Chen Jie Yu Wenhui Ma Yuping Li Ni Yang | 2018 | Journal of Materials Science & Technology2018，34，9： | 3 |
| 14 | A single nucleotide substitution at 5'-UTR of GSN1 represses its translation and leads to an increase of grain length in rice显示文摘Rice grain size is an important trait that affects rice yield and quality, and thus the identification of genes related to grain size is of great significance for improving rice yield and quality. Many genes related to grain size, such as DEP1(Huang et al., 2009),GW5(Liu et al., 2017). | Xia Zhang Peng Qin Youlin Peng Bo Ma Jiangbo Hu Shijun Fan Binhua Hu Guohua Zhang Hua Yuan Wei Yan Weilan Chen Bin Tu Hang He Bingtian Ma Yuping Wang Shigui Li | 2019 | Journal of Genetics and Genomics2019，46，2： | 2 |
| 15 | PM_(2.5)and water-soluble inorganic ion concentrations decreased faster in urban than rural areas in China显示文摘We investigated variations of PM_(2.5)and water-soluble inorganic ions chemical characteristics at nine urban and rural sites in China using ground-based observations.From 2015 to 2019,mean PM_(2.5)concentration across all sites decreased by 41.9μg/m~3with a decline of 46%at urban sites and 28%at rural sites,where secondary inorganic aerosol(SIAs)contributed to 21%(urban sites)and 17%(rural sites)of the decreased PM_(2.5).SIAs concentrations underwent a decline at urban locations,while sulfate(SO_(4)^(2–)),nitrate(NO_(3)^(–)),and ammonium(NH_(4)^(+))decreased by 49.5%,31.3%and 31.6%,respectively.However,only SO_(4)^(2–)decreased at rural sites,NO_(3)^(–)increased by 21%and NH_(4)^(+)decreased slightly.Those changes contributed to an overall SIAs increase in 2019.Higher molar ratios of NO_(3)^(–)to SO_(4)^(2–)and NH_(4)^(+)to SO_(4)^(2–)were observed at urban sites than rural sites,being highest in the heavily polluted days.Mean molar ratios of NH_(3)/NH_xwere higher in 2019 than 2015 at both urban and rural sites,implying increasing NH_xremained as free NH_(3).Our observations indicated a slower transition from sulfate-driven to nitrate-driven aerosol pollution and less efficient control of NO_(x)than SO_(2)related aerosol formation in rural regions than urban regions.Moreover,the common factor at urban and rural sites appears to be a combination of lower SO_(4)^(2–)levels and an increasing fraction of NO_(3)^(–)to PM_(2.5)under NH_(4)^(+)-rich conditions.Our findings imply that synchronous reduction in NO_(x)and NH_(3)emissions especially rural areas would be effective to mitigate NO_(3)^(–)-driven aerosol pollution. | Yangyang Zhang Aohan Tang Chen Wang Xin Ma Yunzhe Li Wen Xu Xiaoping Xia Aihua Zheng Wenqing Li Zengguo Fang Xiufen Zhao Xianlong Peng Yuping Zhang Jian Han Lijuan Zhang Jeffrey L.Collett Jr Xuejun Liu | 2022 | Journal of Environmental Sciences2022，34，12： | 2 |
| 16 | Red-Emissive Organic Room-Temperature Phosphorescence Material for Time-Resolved Luminescence Bioimaging显示文摘Organic room-temperature phosphorescence(RTP)materials have been used in high-resolution imaging.However,the development of long-wavelength-emis sion RTP materials in aqueous solution remains a challenge.Here,we report red-emissive RTP materials via integration of the ring-fusing effect and host–guest interaction. | Wenbo Dai Yahui Zhang Xinghui Wu Shuai Guo Jieran Ma Jianbing Shi Bin Tong Zhengxu Cai Haiyan Xie Yuping Dong | 2022 | CCS Chemistry2022，4，8： | 2 |
| 17 | Chinese Returnees from Overseas Study:An Understanding of Brain Gain and Brain Circulation in the Age of Globalization显示文摘Among discussions on international academic mobility,a persistent challenge is to understand whether education abroad can become a source of brain gain,and whether globalization can offer source countries the hope that they might enjoy the benefits of freer cross-border flows in information and personnel.With reference to China,this article provides an understanding of these two issues.It reveals practical factors affecting returnees’decision to return,their contribution to specific areas,and obstacles that limit their contribution and career opportunities.In addition,it sheds light on an emerging brain circulation between China and foreign countries,along with the increased cross-border flow of academic talent from and into China. | Yuping MA Suyan PAN | 2015 | Frontiers of Education in China2015，10，2： | 2 |
| 18 | Magnetic transformation of Mn from anti-ferromagnetism to ferromagnetism in FeCoNiZMn_(x)(Z=Si,Al,Sn,Ge)high entropy alloys显示文摘We design high entropy alloys(HEAs) with different induction elements(Si/Al/Sn).In order to keep the crystal structure invariant and to investigate how the increment in saturation magnetization(Ms)is caused only by the change of electron spin state,each set of HEAs contains a different amount of Mn.Synergistic effects among induction elements that induce the magnetic transformation of Mn from anti-ferromagnetism to ferromagnetism are found.Ms of added Mn reduces when a particular induction element(Si_(0.4)/Al_(0.4)/Sn_(0.4)) exists,while a larger increment of Ms appears when two induction elements coexist,Si_(0.4)Al_(0.4)(25.79 emu/g) and Sn_(0.4)Al_(0.4)(15.43 emu/g).This is reflected in the microcosmic magnetic structure for the emergence of closed domains due to large demagnetization energy,which is confirmed by the Lorentz transmission electron microscope(LTEM) data.The calculated magnetic moments and the exchange integral constants from density functional theory based on the Exact Muffin-Tin Orbits fo rmalism reveal that the magnetic state and the strength of fe rromagnetic and anti-ferromagnetic coupling determine the variation of Ms in different chemical environments.The difference in energy levels of coexisting multiple induction elements also leads to a larger increment of Ms,Si_(0.4)Al_(0.4)Sn_(0.4)(29.78 emu/g),and Si_(0.4)Al_(0.4)Ge_(0.4)Sn_(0.4)(31.00 emu/g). | Bin Zhang Yuping Duan Haifeng Zhang Shuo Huang Guojia Ma Tongmin Wang Xinglong Dong Nan Jia | 2021 | Journal of Materials Science & Technology2021，，9： | 2 |
| 19 | Advanced graph model for tainted variable tracking显示文摘The reliability of hardware devices is of critical importance to the overall stability of operating systems.Drivers assume that hardware devices always work normally,but this assumption may cause drivers or systems to crash,since hardware device failures occur frequently.This can lead to incorrect values for drivers and cause them to malfunction.This paper proposes an advanced graph model for tainted variable tracking.The proposed approach can efciently fnd variables,which are related to values read from hardware devices.It can also be used for variable assignment tracking,which is of great beneft in improving the reliability of hardware devices and drivers. | MA Chao YAN Dong WANG YuPing HU ShiMin | 2013 | Science China(Information Sciences)2013，56，11： | 2 |
| 20 | Latest Advances in High-Voltage and High-Energy-Density Aqueous Rechargeable Batteries显示文摘Aqueous rechargeable batteries(ARBs)have become a lively research theme due to their advantages of low cost,safety,environmental friendliness,and easy manufacturing.However,since its inception,the aqueous solution energy storage sys-tem has always faced some problems,which hinders its development,such as the narrow electrochemical stability window of water,poor percolation of electrode materials,and low energy density.In recent years,to overcome the shortcomings of the aqueous solution-based energy storage system,some very pioneering work has been done,which also provides a great inspiration for further research and development of future high-performance aqueous energy storage systems.In this paper,the latest advances in various ARBs with high voltage and high energy density are reviewed.These include aqueous rechargeable lithium,sodium,potassium,ammonium,zinc,magnesium,calcium,and aluminum batteries.Further chal-lenges are pointed out. | Xinhai Yuan Fuxiang Ma Linqing Zuo Jing Wang Nengfei Yu Yuhui Chen Yusong Zhu Qinghong Huang Rudolf Holze Yuping Wu Teunis van Ree | 2021 | Electrochemical Energy Reviews2021，4，1： | 2 |
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