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| 1 | Association between Helicobacterpylori, Epstein-Barr virus, human papillomavirus and gastric adenocarcinomas显示文摘AIM To correlate Helicobacter pylori(H. pylori), Epstein-Barr virus(EBV) and human papillomavirus(HPV) with gastric cancer(GC) cases in Pará State, Brazil.METHODS Tissue samples were obtained from 302 gastric adenocarcinomas. A rapid urease test was used to detect the presence of H. pylori, and the presence of the cagA gene in the HP-positive samples was confirmed by PCR. An RNA in situ hybridization test designed to complement Eber1 RNA was used to detect the presence of EBV in the samples, and the L1 region of HPV was detected using nested PCR. Positive HPV samples were genotyped and analyzed for E6 and E7 viral gene expression. Infections were also correlated with the clinical and pathological characteristics of the patients.RESULTS The majority of the 302 samples analyzed were obtained from men(65%) aged 55 years or older(67%) and were classified as the intestinal subtype(55%). All three pathogens were found in the samples analyzed in the present study(H. pylori : 87%, EBV: 20%, HPV: 3%). Overall, 78% of the H. pylori-positive(H. pylori+) samples were cag A +(H. pylori-cag A+), and there was an association between the cytotoxic product of this gene and EBV. Coinfections of H. pylori-cagA+ and EBV were correlated with the most advanced tumor stages. Although only 20% of the tumors were positive for EBV, infection with this virus was associated with distant metastasis. Only the HPV 16 and 18 strains were found in the samples, although no expression of the E6 and E7 oncoproteins was detected. The fundus of the stomach was the region least affected by the pathogens.CONCLUSION HPV was not involved in gastric tumorigenesis. Prophylactic and therapeutic measures against H. pylori and EBV may prevent the development of GC, especially the more aggressive forms. | Carolina Rosal Teixeira de Souza Marcelli Carolini Alves Almeida Andre Salim Khayat Emerson Lucena da Silva Paulo Cardoso Soares Luiz Claudio Chaves Rommel Mario Rodriguez Burbano | 2018 | World Journal of Gastroenterology2018，24，43： | 6 |
| 2 | Analysis of the postoperative hemostatic profile of colorectal cancer patients subjected to liver metastasis resection surgery显示文摘BACKGROUND Liver resection surgery has advanced greatly in recent years,and the adoption of fasttrack programs has yielded good results.Combination anesthesia (general anesthesia associated to epidural analgesia) is an anesthetic-analgesic strategy commonly used for the perioperative management of patients undergoing surgery of this kind,though there is controversy regarding the coagulation alterations it may cause and which can favor the development of spinal hematomas.AIM To study the postoperative course of liver resection surgery,an analysis was made of the outcomes of liver resection surgery due to colorectal cancer metastases in our centre in terms of morbiditymortality and hospital stay according to the anesthetic technique used (general vs combination anesthesia).METHODS A prospective study was made of 61 colorectal cancer patients undergoing surgery due to liver metastases under general and combination anesthesia between January 2014 and October 2015.The patient characteristics,intraoperative variables,postoperative complications,evolution of hemostatic parameters,and stay in intensive care and in hospital were analyzed.RESULTS A total of 61 patients were included in two homogeneous groups: general anesthesia (n = 30) and combination anesthesia (general anesthesia associated to epidural analgesia)(n = 31).All patients had normal coagulation values before surgery.The international normalized ratio (INR) in both the general and combination anesthesia groups reached maximum values at 2448 h (mean 1.37 and 1.45 vs 1.39 and 1.41,respectively),followed by a gradual decrease.There was less intraoperative bleeding in the combination anesthesia group (769 mL) than in the general anesthesia group (1200 mL)(P < 0.05).Of the 61 patients,38.8% in the general anesthesia group experienced some respiratory complication vs 6.6% in the combination anesthesia group (P < 0.001).The time to gastrointestinal tolerance was significantly correlated to the type of anesthesia,though not so the stay in critical care or the time to hospital discharge.CONCLUSION Epidural analgesia in liver resection surgery was seen to be safe,with good results in terms of pain control and respiratory complications,and with no associated increase in complications secondary to altered hemostasis. | Guillermo Perez Navarro Ana Maria Pascual Bellosta Sonia María Ortega Lucea Mario Serradilla Martín Jose Manuel Ramirez Rodriguez Javier Martinez Ubieto | 2019 | World Journal of Clinical Cases2019，7，17： | 4 |
| 3 | Prediction of the airblast wave effects near a tunnel advanced by drilling and blasting 显示文摘 | RAFAEL RODRIGUEZ JAVIER TORANO MARIO MENENDEZ | 2007 | Tunnelling and Underground Space Technology2007，22，： | 1 |
| 4 | Ketosis-Prone Diabetes: Dissection of a Heterogeneous Syndrome Using an Immunogenetic and β-Cell Functional Classification, Prospective Analysis, and Clinical Outcomes显示文摘 | Mario Maldonado Christiane S. Hampe Lakshmi K. Gaur Susana D’Amico Dinakar Iyer Lisa P. Hammerle Douglas Bolgiano Lucille Rodriguez Arun Rajan ?ke Lernmark Ashok Balasubramanyam | 2003 | The Journal of Clinical Endocrinology & Metabolism2003，，11： | 1 |
| 5 | Tests on a half-scale two-story seismic resisting precast concrete building 显示文摘 | Rodriguez Mario E Blandon J J | 2005 | PCI Journal2005，50，1： | 1 |
| 6 | A measure of the capacity of earthquake ground motions to damage structures显示文摘 | Mario Rodriguez | 1994 | Earthquake Engineering and Structural Dynamics1994，23，2： | 1 |
| 7 | Behavior of Connections and Floor diaphragms in Seismic - Resisting Precast Concrete Buildings 显示文摘 | Blandon John J Mario E Rodriguez | 2005 | PCI Journal2005，，2： | 1 |
| 8 | Evolution of Bacillus thuringiensis Cry toxins insecticidal activity显示文摘 | Alejandra Bravo Isabel Gómez Helena Porta Blanca Ines García‐Gómez Claudia Rodriguez‐Almazan Liliana Pardo Mario Soberón | 2012 | Microbial Biotechnology2012，，1： | 1 |
| 9 | Endoplasmic reticulum: ER stress regulates mitochondrial bioenergetics显示文摘 | Roberto Bravo Tomás Gutierrez Felipe Paredes Damián Gatica Andrea E. Rodriguez Zully Pedrozo Mario Chiong Valentina Parra Andrew F.G. Quest Beverly A. Rothermel Sergio Lavandero | 2011 | International Journal of Biochemistry and Cell Biology2011，，： | 1 |
| 10 | Assessing representativeness of protected natural areas in Costa Rica for conserving biediversity: A preliminary gap analysis 显示文摘 | George V N Powell James Barborak Mario Rodriguez S | 2000 | Biological Conservation2000，93，： | 1 |
| 11 | Synthesis of polyols by anionic polymerization: determination of kinetic parameters of propylene oxide polymerization using caesium and potassium alcoholates 显示文摘 | ATONIO De Lucas LOURDES Rodriguez MARIO Perez-Collado | 2002 | Polymer International2002，51，： | 1 |
| 12 | When Lithium Hurts: A Look at Ebstein Anomaly显示文摘 | Stephen Osiro Kevin J. Tiwari Njambi Mathenge Jonier R. Rodriguez R. Shane Tubbs Marios Loukas | 2013 | Cardiology in Review2013，，5： | 1 |
| 13 | Dark-lumen MR colonography with fecal tagging: a comparison of water enema and air methods of colonic distension for detecting colonic neoplasms显示文摘 | Sonia Rodriguez Gomez Mario Pagés Llinas Antoni Castells Garangou Carmen Juan Garcia Josep M. Bordas Alsina Jordi Rimola Gibert Juan R. Ayuso Colella Carmen Ayuso Colella | 2008 | European Radiology2008，，7： | 1 |
| 14 | A measure of the capacity of earthquake ground motions to damage structures显示文摘 | Mario Rodriguez | 1994 | Earthquake Engineering and Structural Dynamics1994，23，2： | 1 |
| 15 | Carbon sequestration and farm income in West Africa: Identifying best management practices for smallholder agricultural systems in northern Ghana显示文摘 | Ernesto González-Estrada Luis C. Rodriguez Valerie K. Walen Jesse B. Naab Jawoo Koo James W. Jones Mario Herrero Philip K. Thornton | 2008 | Ecological Economics2008，，3： | 1 |
| 16 | A Damage Index for the Seismic Analysis of Reinforced Concrete Members显示文摘 | Mario E. Rodriguez Daniel Padilla | 2009 | Journal of Earthquake Engineering2009，，3： | 1 |
| 17 | Behavior of Connections and Floor diaphragms in Seismic-Resisting Precast concrete Buildings显示文摘 | Blandon John J Mario E Rodriguez | 2005 | PCI Journal2005，，2： | 1 |
| 18 | Decline in subarachnoid haemorrhage volumes associated with the first wave of the COVID- 19 pandemic显示文摘Background During the COVID-19 pandemic,decreased volumes of stroke admissions and mechanical thrombectomy were reported.The study’s objective was to examine whether subarachnoid haemorrhage(SAH)hospitalisations and ruptured aneurysm coiling interventions demonstrated similar declines.Methods We conducted a cross-sectional,retrospective,observational study across 6 continents,37 countries and 140 comprehensive stroke centres.Patients with the diagnosis of SAH,aneurysmal SAH,ruptured aneurysm coiling interventions and COVID-19 were identified by prospective aneurysm databases or by International Classification of Diseases,10th Revision,codes.The 3-month cumulative volume,monthly volumes for SAH hospitalisations and ruptured aneurysm coiling procedures were compared for the period before(1 year and immediately before)and during the pandemic,defined as 1 March-31 May 2020.The prior 1-year control period(1 March-31 May 2019)was obtained to account for seasonal variation.Findings There was a significant decline in SAH hospitalisations,with 2044 admissions in the 3 months immediately before and 1585 admissions during the pandemic,representing a relative decline of 22.5%(95%CI−24.3%to−20.7%,p<0.0001).Embolisation of ruptured aneurysms declined with 1170-1035 procedures,respectively,representing an 11.5%(95%CI−13.5%to−9.8%,p=0.002)relative drop.Subgroup analysis was noted for aneurysmal SAH hospitalisation decline from 834 to 626 hospitalisations,a 24.9%relative decline(95%CI−28.0%to−22.1%,p<0.0001).A relative increase in ruptured aneurysm coiling was noted in low coiling volume hospitals of 41.1%(95%CI 32.3%to 50.6%,p=0.008)despite a decrease in SAH admissions in this tertile.Interpretation There was a relative decrease in the volume of SAH hospitalisations,aneurysmal SAH hospitalisations and ruptured aneurysm embolisations during the COVID-19 pandemic.These findings in SAH are consistent with a decrease in other emergencies,such as stroke and myocardial infarction. | Thanh N Nguyen Diogo C Haussen Muhammad M Qureshi Hiroshi Yamagami Toshiyuki Fujinaka Ossama Y Mansour Mohamad Abdalkader Michael Frankel Zhongming Qiu Allan Taylor Pedro Lylyk Omer F Eker Laura Mechtouff Michel Piotin Fabricio Oliveira Lima Francisco Mont'Alverne Wazim Izzath Nobuyuki Sakai Mahmoud Mohammaden Alhamza R Al-Bayati Leonardo Renieri Salvatore Mangiafico David Ozretic Vanessa Chalumeau Saima Ahmad Umair Rashid Syed Irteza Hussain Seby John Emma Griffin John Thornton Jose Antonio Fiorot Rodrigo Rivera Nadia Hammami Anna M Cervantes-Arslanian Hormuzdiyar H Dasenbrock Huynh Le Vu Viet Quy Nguyen Steven Hetts Romain Bourcier Romain Guile Melanie Walker Malveeka Sharma Don Frei Pascal Jabbour Nabeel Herial Fawaz Al-Mufti Atilla Ozcan Ozdemir Ozlem Aykac Dheeraj Gandhi Chandril Chugh Charles Matouk Pascale Lavoie Randall Edgell Andre Beer-Furlan Michael Chen Monika Killer-Oberpfalzer Vitor Mendes Pereira Patrick Nicholson Vikram Huded Nobuyuki Ohara Daisuke Watanabe Dong Hun Shin Pedro SC Magalhaes Raghid Kikano Santiago Ortega-Gutierrez Mudassir Farooqui Amal Abou-Hamden Tatsuo Amano Ryoo Yamamoto Adrienne Weeks Elena A Cora Rotem Sivan-Hoffmann Roberto Crosa Markus Möhlenbruch Simon Nagel Hosam Al-Jehani Sunil A Sheth Victor S Lopez Rivera James E Siegler Achmad Fidaus Sani Ajit S Puri Anna Luisa Kuhn Gianmarco Bernava Paolo Machi Daniel G Abud Octavio M Pontes-Neto Ajay K Wakhloo Barbara Voetsch Eytan Raz Shadi Yaghi Brijesh P Mehta Naoto Kimura Mamoru Murakami Jin Soo Lee Ji Man Hong Robert Fahed Gregory Walker Eiji Hagashi Steve M Cordina Hong Gee Roh Ken Wong Juan F Arenillas Mario Martinez-Galdamez Jordi Blasco Alejandro Rodriguez Vasquez Luisa Fonseca M Luis Silva Teddy Y Wu Simon John Alex Brehm Marios Psychogios William J Mack Matthew Tenser Tatemi Todaka Miki Fujimura Roberta Novakovic Jun Deguchi Yuri Sugiura Hiroshi Tokimura Rakesh Khatri Michael Kelly Lissa Peeling Yuichi Murayama Hugh Stephen Winters Johnny Wong Mohamed Teleb Jeremy Payne Hiroki Fukuda Kosuke Miyake Junsuke Shimbo Yusuke Sugimura Masaaki Uno Yohei Takenobu Yuji Matsumaru Satoshi Yamada Ryuhei Kono Takuya Kanamaru Masafumi Morimoto Junichi Iida Vasu Saini Dileep Yavagal Saif Bushnaq Wenguo Huang Italo Linfante Jawad Kirmani David S Liebeskind Viktor Szeder Ruchir Shah Thomas G Devlin Lee Birnbaum Jun Luo Anchalee Churojana Hesham E Masoud Carlos Ynigo Lopez Brendan Steinfort Alice Ma Ameer E Hassan Amal Al Hashmi Mollie McDermott Maxim Mokin Alex Chebl Odysseas Kargiotis Georgios Tsivgoulis Jane G Morris Clifford J Eskey Jesse Thon Leticia Rebello Dorothea Altschul Oriana Cornett Varsha Singh Jeyaraj Pandian Anirudh Kulkarni Pablo M Lavados Veronica V Olavarria Kenichi Todo Yuki Yamamoto Gisele Sampaio Silva Serdar Geyik Jasmine Johann Sumeet Multani Artem Kaliaev Kazutaka Sonoda Hiroyuki Hashimoto Adel Alhazzani David Y Chung Stephan A Mayer Johanna T Fifi Michael D Hill Hao Zhang Zhengzhou Yuan Xianjin Shang Alicia C Castonguay Rishi Gupta Tudor G Jovin Jean Raymond Osama O Zaidat Raul G Nogueira SVIN COVID-19 Registry,the Middle East North Africa Stroke and Interventional Neurotherapies Organization(MENA-SINO),Japanese Society of Vascular and Interventional Neurology Society(JVIN) | 2021 | Stroke & Vascular Neurology2021，6，4： | 0 |
| 19 | G-StarRAW总部显示文摘G-Star RAW新总部位于阿姆斯特丹Zuid-Oost工业区内的A10路旁,其单栋建筑集G-Star RAW各类不同设施于一身,旨在刺激各部门间的互动合作。
横向的总部大楼长140m,面积达27 500m2,由一个容纳G-Star RAW各个核心部门的"创作核"组成,外围则是办公室、停车位和配套设施。 | Katrien van Dijk Michel van de Kar Tjeerd van de Sandt Saskia Simon Mario Rodriguez Marina Cogliani Jung-Won Yoon Marlies Boterman Marina Coglianiv Karolina Czeczek Green van Gogh Sarah Moylan Mafalda Rangel Richard Hollington Ⅲ Fred Awty Philippe Braun Kaveh Dabiri Hans Hammink Mariano Sagasta Koen Stockbroekx | 2014 | 城市环境设计2014，，6： | 0 |
| 20 | Oregano and Composite Substrates: A Mitigation Alternative for Heavy Metals Emission from Tailings Deposits in Parral, Chihuahua, Mexico显示文摘 | Luis Miguel Rodriguez Vazquez Mario Lorenzo Franco Soto Magdiel Aaron Solis Lozoya Luis Manuel Saenz Macias Ever Ulysses Torres Carrillo Emilio Yanez Terrazas Eduardo Florencio Herrera Peraza Ramon Silva Vazquez | 2017 | Journal of Environmental Science and Engineering(A)2017，6，3： | 0 |
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