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| 1 | Comparing the Diagnostic Criteria for Gestational Diabetes Mellitus of World Health Organization 2013 with 1999 in Chinese Population显示文摘INTRODUCTION Gestational diabetes mellitus (GDM) was earlier defined as 'hyperglycemia first recognized during pregnancy' and has more recently been described by American Diabetes Association (ADA) (2012) as diabetes diagnosed during pregnancy that is not clearly overt diabetes.[1] The hyperglycemia and adverse pregnancy outcomes study (HAPO) demonstrated that the risk of adverse maternal,fetal,and neonatal outcomes continuously increase as a function of maternal glycemia at 24-28 weeks,even within ranges previously considered normal for pregnancy.[2] After reviewing the results of the HAPO study,many international diabetes study groups,including the International Association of Diabetes and Pregnancy Study Groups and ADA have adopted the 75 g oral glucose tolerance test (OGTT) at 24-28 weeks as a screening and diagnostic test and defined new cut-off values for GDM diagnosis.The Ministry of Health of China published the criteria for GDM,that is the same as the ADA criteria on July 1,2011.World Health Organization (WHO) has recommended the 75 g OGTT with different cut-offvalues as a diagnostic test since 1999,changed its recommendation on 2013.In Hongkong and Yunnan province in China,most hospital adopted the WHO 1999 criteria,nevertheless,there is no evidence of multicenter and large sample to show that the GDM population within the same ethnic group diagnosed by the new WHO criteria matches those diagnosed by the old one and consistency between the two criteria has not been reported.Thus,we conducted this study to analyze the two criteria in Chinese pregnant women. | Weiwei Zhu Huixia Yang Yumei Wei Zilian Wang Xuelan Li Hairong Wu Nan Li Meihua Zhang Xinghui Liu Hua Zhang Yunhui Wang Jianmin Niu Yujie Gan Liruo Zhong Yunfeng Wang Anil Kapur | 2015 | Chinese Medical Journal2015，，1： | 42 |
| 2 | Volcanism at the Permian-Triassic Boundary in South China and Its Effects on Mass Extinction显示文摘This paper discusses the clayrocks widespread at the Permian-Triassic boundary, which are mostly of volcanic origin. Volcanogenetic textures, structures and minerals such as high-temperature quartz are found in clayrocks at the Permian-Triassic boundary in many places. Thousands of microspherules have been collected from the Boundary clayrocks, many of which exhibit the typical features of the process from melting to cooling and solidification. indicating that they were formed by volcanic eruption or extraterrestrial impact. Volcanic effects on the Permian-Triassic mass extinction may be reflected in conodonts, algae and ammonoids. The Boundary clayrocks are found in many Permian-Triassic sections along the coast of Tethys. Their orighin remains to be studied. | Yin Hongfu, Huang Siji, Zhang Kexin, Yang Fengqing, Ding Meihua, Bi Xianmei and Zhang Suxin China University of Geosciences, Wuhan, Hubei | 1989 | Acta Geologica Sinica(English Edition)1989，63，4： | 22 |
| 3 | Three-dimensional Finite Element Analysis of the Mechanical Properties of Helical Thread Connection显示文摘Conventional analytical and numerical methods for the mechanical properties of helical threads are relied on many assumptions and approximations and thus hardly yield satisfied results. A parameterized 3D finite element model of bolted joints with real helical thread geometry is established and meshed with refined hexahedral elements. The Von Mises plasticity criterion, kinematic hardening rule of materials and interfacial contacts are employed to make it possible for the suggested model be able to approach real assembly conditions. Then, the mechanical properties of bolted joints with different thread pitches, thread numbers and modular ratios are investigated, including the contact pressure distribution at joint interfaces, the axial load distribution and stress concentration in screw threads during the loading and unloading process. Simulation results indicate that the load distribution in screw threads produced by the suggested model agrees well the results from CHEN's photoelastic tests. In addition, an interesting phenomenon is found that tightening the bolt with a large preload first and then adjusting the clamping force by unloading can make the load distribution more uniform and reduce the maximum residual equivalent stress in thread roots by up to 40%. This research provides a simple and practical approach to constructing the 3D finite element model and predicting the mechanical properties of helical thread connection. | YANG Guoqing HONG Jun ZHU Linbo LI Baotong XIONG Meihua WANG Fei | 2013 | Chinese Journal of Mechanical Engineering2013，26，3： | 19 |
| 4 | Safety issues and new rapid detection methods in traditional Chinese medicinal materials显示文摘The safety of traditional Chinese medicine(TCM) is a major strategic issue that involves human health. With the continuous improvement in disease prevention and treatment, the export of TCM and its related products has increased dramatically in China. However, the frequent safety issues of Chinese medicine have become the ‘bottleneck' impeding the modernization of TCM. It was proved that mycotoxins seriously affect TCM safety; the pesticide residues of TCM are a key problem in TCM international trade; adulterants have also been detected, which is related to market circulation. These three factors have greatly affected TCM safety. In this study, fast, highly effective, economically-feasible and accurate detection methods concerning TCM safety issues were reviewed, especially on the authenticity, mycotoxins and pesticide residues of medicinal materials. | Lili Wang Weijun Kong Meihua Yang Jianping Han Shilin Chen | 2015 | Acta Pharmaceutica Sinica B2015，5，1： | 18 |
| 5 | Surface latent heat flux anomalies prior to the Indonesia Mw9.0 ear thquakeof 2004显示文摘The temporal and spatial variations of surface latent heat flux (SLHF) before and after the Mw9.0 earthquake that occurred on the west coast of Sumatra, Indonesia on 26 December 2004 are summarized. It is found that before the earthquake significant SLHF anomalies occurred at the epicentral area and its vicinity. The largest SLHF anomaly oc- curred on the subduction zone in the middle part of Burma micro-plate, where the middle part of the rup- ture zone is located and the aftershocks are concen- trated. The developments of the anomaly involved growing of the anomaly from small to large and spreading of the anomaly from disordered to con- centrated. The anomaly began to occur on the east extensional boundary of the Burma micro-plate and its adjacent oceanic basin, and then propagated to the west compressive boundary, where the subduc- tion zone exists. Finally, the anomaly disappeared after the main shock. The seismic source is consid- ered to be a dissipation system. The increase of stress prior to an earthquake may enhance the ex- change of energy and material between the seismic source system and the outer system, resulting in the increase of the rate of energy exchange between sea surface and atmosphere, which is believed to be the main reason of the generation of SLHF anomaly. | CHEN Meihua DENG Zhihui YANG Zhuzhuan MA Xiaojing | 2006 | Chinese Science Bulletin2006，51，8： | 14 |
| 6 | Present Terrestrial Heat Flow Measurements of the Geothermal Fields in the Chagan Sag of the YingenEjinaqi Basin,Inner Mongolia,China显示文摘Owing to the lack o f terrestrial heat flow data, studying lithospheric thermal structure and geodynamics of the Yingen-Ejinaqi Basin in Inner Mongolia is limited. In this paper, the terrestrial heat flow o f the Chagan sag in the YingenEjinaqi Basin were calculated by 193 system steady-state temperature measurements of 4 wells, and newly measuring 62 rock thermal conductivity and 20 heat production rate data on basis o f the original 107 rock thermal conductivity and 70 heat production data. The results show that the average thermal conductivity and heat production rate are 2.11 ±0.28 W/(m.K) and2.42±0.25 nW/m^3 in the Lower Cretaceous o f the Chagan sag. The average geothermal gradient from the Lower Suhongtu 2 Formation to the Suhongtu 1 Fonnation is 37.6 °C/km, and that o f the Bayingebi 2 Formation is 27.4 °C/km. Meanwhile, the average terrestrial heat flow in the Chagan sag is 70.6 mW/m^2. On the above results, it is clear that there is an obvious negative correlation between the thermal conductivity o f the stratum and its geothermal gradient. Moreover, it reveals that there is a geothermal state between tectonically stable and active areas. This work may provide geothermal parameters for further research o f lithospheric thermal structure and geodynamics in the Chagan sag. | FENG Renpeng ZUO Yinhui YANG Meihua ZHANG Jiong LIU Zhi ZHOU Yongshui HAO Qingqing | 2019 | Acta Geologica Sinica(English Edition)2019，93，2： | 6 |
| 7 | Enhanced photodynamic therapy of mixed phase TiO2(B)/anatase nanofibers for killing of HeLa cells显示文摘光力学的治疗(太平洋夏季时间) 是使用使药具有感光性有选择地使用治疗指向地点的一个过程,被证明了是为可以发展成癌症的癌症和条件的安全治疗。缩放 Nano 的 TiO < 潜水艇 class= “ a-plus-plus ” > 2 为紫外轻驾驶太平洋夏季时间被认为是潜在的 photosensitizer。在这研究, TiO 的四种类型<潜水艇class=“ a-plus-plus ”> 2 nanofibers 从质子 tri-titanate 被准备( H <潜水艇class=“ a-plus-plus ”> 2 T <潜水艇class=“ a-plus-plus ”> 3 O <潜水艇class=“ a-plus-plus ”> 7 ) nanofiber 。同样获得的 nanofibers 为太平洋夏季时间杀死 HeLa 房间作为有效 photosensitizers 被表明。MTT 试金和流动 cytometry (FCM ) 被执行评估 biocompatibility, apoptotic 房间的百分比,和房间生存能力。同样准备的 TiO 的 non-cytotoxicity < 潜水艇 class= “ a-plus-plus ” > 当紫外照耀不在时的 2 nanofibers 也被表明了。在紫外轻照耀下面, TiO < 潜水艇 class= “ a-plus-plus ” > 2 nanofibers,特别地混合阶段 nanofibers,比 Pirarubicin (THP ) 显示了高得多的杀死房间的效率,它是普通的药导致 HeLa 房间的 apoptosis。我们归功于混合阶段 nanofibers 的高 cellkilling 效率到在 TiO 之间的 bandgap 边比赛和稳定的接口 < 候补选手 class= “ a-plus-plus ” > 2 (B) 和锐钛矿在单个 nanofiber 分阶段执行,它能禁止 photogenerated 电子和洞的再结合。这支持费用分离和转移过程和罐头生产负责杀死 HeLa 房间的更多的反应的氧种类(ROS ) 。 | Shuchao Zhang Dongjiang Yang Dengwei Jing Hongwei Liu Long Liu Yi Jia Meihua Gao Liejin Guo Ziyang Huo | 2014 | Nano Research2014，7，11： | 6 |
| 8 | Serine metabolism orchestrates macrophage polarization by regulating the IGF1–p38 axis显示文摘Serine metabolism is reportedly involved in immune cell functions, but whether and how serine metabolism regulates macrophage polarization remain largely unknown. Here, we show that suppressing serine metabolism, either by inhibiting the activity of the key enzyme phosphoglycerate dehydrogenase in the serine biosynthesis pathway or by exogenous serine and glycine restriction, robustly enhances the polarization of interferon-γ-activated macrophages (M(IFN-γ)) but suppresses that of interleukin-4-activated macrophages (M(IL-4)) both in vitro and in vivo. Mechanistically, serine metabolism deficiency increases the expression of IGF1 by reducing the promoter abundance of S-adenosyl methionine-dependent histone H3 lysine 27 trimethylation. IGF1 then activates the p38-dependent JAK–STAT1 axis to promote M(IFN-γ) polarization and suppress STAT6-mediated M(IL-4) activation. This study reveals a new mechanism by which serine metabolism orchestrates macrophage polarization and suggests the manipulation of serine metabolism as a therapeutic strategy for macrophage-mediated immune diseases. | Xiao Shan Penghui Hu Lina Ni Long Shen Yanan Zhang Zemin Ji Yan Cui Meihua Guo Haoan Wang Liyuan Ran Kun Yang Ting Wang Lei Wang Bin Chen Zhi Yao Vingjie Wu Qiujing Yu | 2022 | Cellular & Molecular Immunology2022，19，11： | 5 |
| 9 | Post-marketing safety surveillance and reevaluation of Motherwort injection:A clinical study of 10094 cases显示文摘OBJECTIVE:To investigate the safety profiles of Motherwort injection(MI).METHODS:A multi-center,prospective and drugderived hospital intensive monitoring method was conducted to assess the safety of MI in real world applications.This study was based on a very large population after the injection was approved and marketed in China.All patients using the injection in participating hospitals were monitored to determine the incidence,pattern,severity and outcome of associated adverse events.RESULTS:The post-marketing surveillance was performed in 10 094 female patients from April to December,2015.The incidence of adverse drug reactions(ADRs) was 0.79‰(8/10 094).Among the 8 patients,the reported adverse events mainly included systemic abnormalities,such as fever,chills and eyelid edema;skin and appendages disorders,such as pruritus and rash;gastrointestinal disorders,such as nausea,abdominal distension and pain;heart rate and rhythm disorders,such as palpitation and increased heart rate.All of these ADRs were mild in severity.CONCLUSION:In this study the ADRs incidence rate of MI is very low,which supports that it is generally safe for use in obstetric and gynecological diseases.However,the total number of 8 ADRs recorded over a relatively short time span seems limited,and the low number of reports could not represent an absolute guarantee of safety. | Cao Shan Zhang Wenhao Zhao Ziwei Heng Mingli Bu Huaien Wang Hongwu Liu Xinghui Wang Zhong Cai Yan Ma Yuyan Cui Shihong Deng Jihong Ding Guifeng Ding Yajuan Dong Linhong Duan Zhentao Fan Ling Fan Yang Fu Fen He Jing Ji Shuying Jin Lin Li Hong Li Hongying Liao Tao Lu Wei Luo Xiucui Lü Zhihui Ma Fengchun Ma Dafeng Shi Tianyun Sun Juying Sun Xiaotong Teng Hong Wang Jinhua Wang Ruihua Wang Ying Wang Zhengling Xi Jie Xu Minjuan Xu Zhihong Yan Qian Yang Cuirong Yang Yimei Yin Jie Yu Jinhua Yuan Wenjun Zhang Guanli Zhang Meihua Zhao Renfeng Zhong Yonghong Zhou Jian | 2018 | Journal of Traditional Chinese Medicine2018，38，4： | 4 |
| 10 | Formal Analysis and Improvement on Ultralightweight Mutual Authentication Protocols of RFID显示文摘Ultralightweight mutual authentication protocols (UMAP) of Radio frequency identification (RFID) systems have attracted much attention from researchers. Many studies reveal that most of UMAP suffer malicious attack. To improve security of UMAP, formal analysis is performed with Simple promela interpreter (SPIN). Two typical UMAPs, which are RCIA and RAPP, are selected as our case study. A protocol abstract modeling method is presented to make UMAP can be formalized simply. Using SPIN, verification results show that RCIA and RAPP are both vulnerable against desynchronization attack. A Generalized model of UMAP (G-UMAP) and a general patching scheme are presented for resisting the attack. To validate the patching scheme, formal verification is then performed for the improved protocol. SPIN verification shows that the improved RCIA and RAPP both gain higher security. The above proposed modeling method has great significance for similar UMAP analyzing, and the proposed patching scheme is proved to be practical and reliable. | XIAO Meihua LI Wei ZHONG Xiaomei YANG Ke CHEN Jia | 2019 | Chinese Journal of Electronics2019，28，5： | 3 |
| 11 | Proving Mutual Authentication Property of RCIA Protocol in RFID Based on Logic of Events显示文摘The increasing commercialization and massive deployment of radio frequency identification(RFID) systems has raised many security related issues which in return evokes the need of security protocols. Logic of events theory(Lo ET) is a formal method for constructing and reasoning about distributed systems and protocols that involve concepts of security. We propose fresh ciphertext and ciphertext release lemmas to extend Lo ET for analyzing and proving the security of authentication protocols that use symmetric key cryptography more than just digital signature. Based on the extended Lo ET we formally analyze and prove the authentication property of RCIA protocol, which provides mutual authentication between Tag and Reader in RFID system.Our proof approach based on extended Lo ET could be applied to the design and analysis of such ultralightweight RFID mutual authentication protocols. | ZHONG Xiaomei XIAO Meihua ZHANG Tong YANG Ke LUO Yunxian | 2022 | Chinese Journal of Electronics2022，31，1： | 3 |
| 12 | Suggestion of Meishan Section as GlobalStratotype Section and Point (GSSP) of Permian-Triassic Boundary显示文摘ThisdatumwasobtainedfromthetopIcmofthe6cmthickBed3,whereasthedatum0.40isthemeanvalueof6samplesofBed26.TABLE3SUCCESSIONOFTHEPTBMARKERStogetherwithunevenlydistributCdirspikeareheresuggestedasauxiliarymarkersoftheboundary.Significanceofthechemicalanomalieswillbefurtherdiscussedintheparagraphofeventostratigraphy.EVENTOgyRATIGRAPHYACROSSTHEPTBOFMEISnANVolcedcEventThe'WhiteClay'orBed25iscomposedofinterbedsofilliteandaxxedmontmorillonite--illitelayerswithsubordinatekaolinite.The'BlackClay'orBed26isofmixedmontmori? | Yin Hongfu Wu Shunbao Ding Meihua Zhang Kexin Tong Jinnan Yang Fengqing(Faculty of Earth Sciences,China University of Geosciences, Wuhan 430074) | 1995 | Journal of Earth Science1995，14，1： | 3 |
| 13 | Tailoring mesoporous-silica nanoparticles for robust immobilization of lipase and biocatalysis显示文摘nano 搬运人的合理设计为为先进 biocatalysis 的现代的酶固定是批评的。此处,我们与一个高 C18 内容报导修改 octadecylalkyl 的 mesoporous 硅石 nanoparticles (C18-MSNs ) 的合成(~ 19 wt.%) 并且悦耳的毛孔尺寸(1.6-13 nm ) 。增加的恐水病的内容和一个定制的毛孔缩放,这被表明(比脂肪分解酵素的尺寸稍微大) 为使不能调动的脂肪分解酵素的高效负责。优化 C18-MSNs 展览 711 mg/g 和比免费的酶的高 5.23 倍的一项特定的活动的一个装载能力。另外, 93% 起始的活动在复用以后被保留五次,它比性能迄今为止报导了的最好好。我们的调查结果为 biocatalytic 应用为脂肪分解酵素的柔韧的固定铺平道路。 | Mohammad Kalantari Meihua Yu Yannan Yang Ekaterina Strounina Zhengying Gu Xiaodan Huang Jun Zhang Hao Song Chengzhong Yu | 2017 | Nano Research2017，10，2： | 3 |
| 14 | Room temperature ferromagnetism of Ni, (Ni, Li), (Ni, N)-doped ZnO thin films显示文摘Ni-doped ZnO thin films (Ni concentration up to 10 mol%) were generated on Si (100) substrates by a sol-gel technique. The films showed wurtzite structure and no other phase was found. The chemical state of Ni was found to be bivalent by X-ray photoelectron spectroscopy. The results of magnetic measurements at room temperature indicated that the films were ferromagnetic, and magnetic moment decreased with rise of Ni concentration. The magnetization of Ni (10 mol%)-doped ZnO film annealed in nitrogen was lower than that annealed in argon, suggesting that the density of defects had an effect on ferromagnetism. | YE XiaoJuan SONG HaiAn ZHONG Wei QI XiaoSi XU MeiHua JIN ChangQing YANG ZaiXin AU ChakTong DU YouWei | 2010 | 中国科学:技术科学2010，40，2： | 2 |
| 15 | AoATG5 plays pleiotropic roles in vegetative growth,cell nucleus development,conidiation,and virulence in the nematode-trapping fungus Arthrobotrys oligospora显示文摘Autophagy is an evolutionarily conserved process in eukaryotes,which is regulated by autophagy-related genes(ATGs).Arthrobotrys oligospora is a representative species of nematode-trapping(NT)fungi that can produce special traps for nematode predation.To elucidate the biological roles of autophagy in NT fungi,we characterized an orthologous Atg protein,AoAtg5,in A.oligospora.We found that AoATG5 deletion causes a significant reduction in vegetative growth and conidiation,and that the transcript levels of several sporulation-related genes were significantly downregulated during sporulation stage.In addition,the cell nuclei were significantly reduced in theΔAoATG5 mutant,and the transcripts of several genes involved in DNA bio-synthesis,repair,and ligation were significantly upregulated.InΔAoATG5 mutants,the autophagic process was significantly impaired,and trap formation and nematocidal activity were significantly decreased.Comparative transcriptome analysis results showed that AoAtg5 is involved in the regulation of multiple cellular processes,such as autophagy,nitrogen metabolism,DNA biosynthesis and repair,and vesicular transport.In summary,our results suggest that AoAtg5 is essential for autophagy and significantly contributes to vegetative growth,cell nucleus development,sporulation,trap formation,and pathogenicity in A.oligospora,thus providing a basis for future studies focusing on related mechanisms of autophagy in NT fungi. | Duanxu Zhou Yingmei Zhu Na Bai Le Yang Meihua Xie Jiangliu Yang Meichen Zhu Ke-Qin Zhang Jinkui Yang | 2022 | Science China(Life Sciences)2022，65，2： | 2 |
| 16 | National Alveolar Echinococcosis Distribution--China, 2012−2016显示文摘What is already known about this topic?Both alveolar echinococcosis(AE)and cystic echinococcosis are endemic in China,among which alveolar echinococcosis has a very high mortality rate.What is added by this report?The survey results showed the prevalence and scope of AE in China and identified high-risk groups including children,monks,herdsmen and illiterate people.At the same time,all the cases found in the survey(more than 90%of the patients did not go to the hospital for diagnosis and treatment before survey)were promptly diagnosed and treated.What are the implications for public health practice?This study provides information for the development of a plan for AE prevention and control and for the implementation of interventions targeted to high-risk populations. | Canjun Zheng Chuizhao Xue Shuai Han Zhongjie Li Hu Wang Liying Wang Ying Wang Qian Wang Yu Feng Yanyan Hou Xiao Ma Junying Ma Xiumin Han Gongsang Quzhen Xiaofeng Jiang Weidong Guo Xianglin Wu Yaming Yang Lei Cao Fanka Li Weiqi Chen Xinliu Yan Shicheng Yu Meihua Fu Qing Yu Ning Xiao Jiangping Cao Jun Yan Weiping Wu Xiao-nong Zhou | 2020 | China CDC weekly2020，2，1： | 2 |
| 17 | Molecularly imprinted polymer-based solid phase clean-up for analysis of ochratoxin A in ginger and LC-MS/MS confirmation显示文摘 | Jiliang Cao Shujun Zhou Weijun Kong Meihua Yang Li Wan Shihai Yang | 2013 | Food Control2013，，2： | 1 |
| 18 | PKC-SWI6 signaling regulates asexual development,cell wall integrity,stress response,and lifestyle transition in the nematode-trapping fungus Arthrobotrys oligospora显示文摘Predatory fungi possess intricate signal transduction systems that regulate their development and support successful infection of the host.Herein,we characterized three components of the cell wall integrity-controlling pathway,namely protein kinase C(Ao PKC),SLT2-MAPK(Ao SLT2),and SWI6(Ao SWI6),in a representative nematode-trapping fungus Arthrobotrys oligospora,using gene disruption and multi-omics approaches.The phenotypic traits(such as mycelia development,conidiation,stress response,and trap morphogenesis) and metabolic profiles of ΔAopkc and ΔAoswi6 mutants were similar but differed from those of the ΔAoslt2 mutants.Transcriptomic analysis indicated that the genes differentially expressed in the absence of Aoswi6 were involved in DNA replication,repair,and recombination during trap formation.Moreover,the yeast two-hybrid assay showed that Ao PKC interacted with Ao SWI6,suggesting that in A.oligospora,PKC can directly regulate SWI6,bypassing the SLT2signaling cascade.Conclusively,our findings deepen our understanding of the regulatory mechanism of asexual development and lifestyle switching in nematode-trapping fungi. | Meihua Xie Ni Ma Na Bai Le Yang Xuewei Yang Ke-Qin Zhang Jinkui Yang | 2022 | Science China(Life Sciences)2022，65，12： | 1 |
| 19 | Exact cone beam reconstruction for a saddle trajectory显示文摘 | Yang Haiquan Li Meihua Koizumi K | 2006 | Phys Med Biol2006，51，： | 1 |
| 20 | Complete assign- ments of ^1 H and ^13C NMR data for seven arylnaphthalide lig- nans from Justicia procumbens 显示文摘 | Yang Meihua Wu jun Cheny Fang | 2006 | Magn Reson Chem2006，44，7： | 1 |
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