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| 1 | AHA/ASA关于卒中和短暂性脑缺血发作患者卒中预防推荐的更新显示文摘在卒中和短暂性脑缺血发作(transient ischemic attack,TIA)患者卒中预防推荐发表以后,美国心脏协会和美国卒中协会(American Heart Association/American Stroke Association,AHA/ASA)著述委员会对最近的一些试验结果进行了回顾。本文的目的是对这些新资料做简要回顾、更新某些推荐意见并说明进行这些修改的理由。在2个领域已发表了一些新的重要临床试验结果:(1)在非心源性栓塞所致缺血性卒中或TIA患者卒中二级预防中具体抗血小板药的应用;(2)他汀类药物在预防卒中复发中的应用。 | Robert J. Adams Greg Albers Mark J. Alberts Oscar Benavente Karen Furie Larry B. Goldstein Philip Gorelick Jonathan Halperin Robert Harbaugh S. Claiborne Johnston Irene Katzan Margaret Kelly-Hayes Edgar J. Kenton Michael Marks Ralph L. Sacco Lee H. Schwamm 赵洪芹 李海峰 (译) | 2008 | 国际脑血管病杂志2008，16，4： | 123 |
| 2 | 婴幼儿卒中的处理:来自美国心脏协会卒中委员会和青少年心血管病委员会专门写作组的科学声明显示文摘目的:本声明旨在回顾有关儿童卒中的文献,为最佳的诊断和治疗提供推荐意见,供负责诊断和治疗婴儿、儿童和青少年脑血管病的医生使用。方法:写作组成员由美国心脏协会卒中委员会科学声明监督委员会任命,由多个不同领域的专家组成。应用美国心脏协会卒中委员会的证据分级标准对每条推荐意见进行分级。在经过小组成员审查后,草稿由4位同行评议专家和卒中委员会指导委员会成员审阅,并由美国心脏协会科学咨询和协调委员会批准。我们预计该声明需在4年内进行更新。结果:为镰状细胞病、烟雾病、颈一脑动脉夹层分离和心源性栓塞引起的缺血性卒中的预防提供循证推荐,同时为出血性卒中的评价和处理提供推荐意见。提出儿童使用肝素和华法林的剂量方案。另外,还为围产期卒中和儿童脑静脉窦血栓形成的评价和处理提供推荐。 | E.Steve Roach(著) Meredith R. Golomb(著) Robert Adams(著) Jose Biller(著) Stephen Daniels(著) Gabrielle deVeber(著) Donna Ferriero(著) Blaise V. Jones(著) Fenella J. Kirkham(著) R. Michael Scott(著) Edward R. Smith(著) 刘丽芳(译) 王胜男(译) 王伟(译) 林镇洲(译) 朱佳佳(译) 潘速跃(译) | 2008 | 国际脑血管病杂志2008，16，11： | 60 |
| 3 | 腰椎终板骨折特点及相关因素的实验研究显示文摘目的探讨腰椎椎体终板压迫骨折的特点及其影响因素。方法19个尸体标本的腰椎运动节段(FSU),根据X线检查来确定椎间盘的退变分级,在双能X线吸收仪器(DEXA)上测量椎体和椎体终板的骨密度(BMD)和骨矿含量(BMC),然后分别承受过度负荷导致终板骨折,根据力-位移曲线来确定终板骨折和终板的极限负荷(FL)。终板骨折后,运动节段解剖为单独的椎体,观察终板骨折情况。结果19个FSU标本中,16个发生肉眼可见的终板骨折,骨折仅仅发生在下位椎体的上终板,比率为84.2%,骨折均位于终板的中央部分或前部,表现为星形放射状、阶梯状、局部突入型等;终板的FL与椎体及终板的BMD、BMC呈正相关。同一个椎体内,上终板的BMD、BMC显著低于下终板,而同一个椎间盘周围,上终板的BMD高于下终板者,BMC却无差异。结论终板压迫骨折易发生于椎体的上终板;不同退变程度椎间盘邻近终板骨折的特点不同,但这种骨折在X线片上很难显现,终板的极限负荷与椎体终板的BMD、BMC呈正相关。 | 赵凤东 范顺武 Patricia Dolan Michael Adams | 2006 | 中华外科杂志2006，44，16： | 16 |
| 4 | Optimal timing and route of nutritional support after esophagectomy: A review of the literature显示文摘Some controversy surrounds the postoperative feeding regimen utilized in patients who undergo esophagectomy.Variation in practices during the perioperative period exists including the type of nutrition started,the delivery route,and its timing.Adequate nutrition is essential for this patient population as these patients often present with weight loss and have altered eating patterns after surgery,which can affect their ability to regain or maintain weight.Methods of feeding after an esophagectomy include total parenteral nutrition,nasoduodenal/nasojejunal tube feeding,jejunostomy tube feeding,and oral feeding.Recent evidence suggests that early oral feeding is associated with shorter LOS,faster return of bowel function,and improved quality of life.Enhanced recovery pathways after surgery pathways after esophagectomy with a component of early oral feeding also seem to be safe,feasible,and cost-effective,albeit with limited data.However,data on anastomotic leaks is mixed,and some studies suggest that the incidence of leaks may be higher with early oral feeding.This risk of anastomotic leak with early feeding may be heavily modulated by surgical approach.No definitive data is currently available to definitively answer this question,and further studies should look at how these early feeding regimens vary by surgical technique.This review aims to discuss the existing literature on the optimal route and timing of feeding after esophagectomy. | Richard Zheng Courtney L Devin Michael J Pucci Adam C Berger Ernest L Rosato Francesco Palazzo | 2019 | World Journal of Gastroenterology2019，25，31： | 11 |
| 5 | Implications of preoperative hypoalbuminemia in colorectal surgery显示文摘Serum albumin has traditionally been used as a quantitative measure of a patient's nutritional status because of its availability and low cost. While malnutrition has a clear definition within both the American and European Societies for Parenteral and Enteral Nutrition clinical guidelines, individual surgeons often determine nutritional status anecdotally. Preoperative albumin level has been shown to be the best predictor of mortality after colorectal cancer surgery. Specifically in colorectal surgical patients, hypoalbuminemia significantly increases the length of hospital stay, rates of surgical site infections, enterocutaneous fistula risk, and deep vein thrombosis formation. The delay of surgical procedures to allow for preoperative correction of albumin levels in hypoalbuminemic patients has been shown to improve the morbidity and mortality in patients with severe nutritional risk. The importance of preoperative albumin levels and the patient's chronic inflammatory state on the postoperative morbidity and mortality has led to the development of a variety of surgical scoring systems to predict outcomes efficiently. This review attempts to provide a systematic overview of albumin and its role and implications in colorectal surgery. | Adam Truong Mark H Hanna Zhobin Moghadamyeghaneh Michael J Stamos | 2016 | World Journal of Gastrointestinal Surgery2016，8，5： | 9 |
| 6 | Therapy-refractory gastrointestinal motility disorder in a child with c-kit mutations显示文摘Constipation and fecal impaction are frequent and distressing complaints in pediatric gastroenterology. Especially in neurologically handicapped children, treatment of severe forms of slow-transit constipation (STC) can be difficult. In the majority of cases, STC is of unknown etiology. However, in recent years, there is growing evidence that interstitial cells of Cajal (ICCs), which serve as electrical pacemakers and generate spontaneous electrical slow waves in the gastrointestinal tract, might play an important role in the pathophysiology of STC. It remains unclear whether morphological ICC alterations seen in affected patients are based on congenital developmental anomalies, or whether they are a consequence of long-term constipation with secondary damage of the gastrointestinal nervous system. To the best of our knowledge, we present the first case of a patient with histological alterations in ICC morphology who displayed multiple alterations of c-kit at the level of mRNA. The protein encoded by c-kit is the receptor tyrosine kinase Kit (CD117), which is crucial for development and function of ICCs. Therefore, these findings provide a new explanation for congenital alterations of ICC development that result in gastrointestinal motility disorders. | Christian Breuer Jun Oh Gerhard J Molderings Michael Schemann Birgit Kuch Ertan Mayatepek Rüdiger Adam | 2010 | World Journal of Gastroenterology2010，16，34： | 7 |
| 7 | Differential gene expression in nontransgenic and transgenic“M.26”apple overexpressing a peach CBF gene during the transition from eco-dormancy to bud break显示文摘The CBF signal pathway is responsible for a significant portion of plant responses to low temperature and freezing.Overexpression of CBF genes in model organisms such as Arabidopsis thaliana enhances abiotic stress tolerance but also reduces growth.In addition to these effects,overexpression of the peach(Prunus persica[L.]Batsch)CBF1 gene in transgenic apple(Malus x domestica Borkh.)line T166 also results in early entry into and late exit from dormancy.Although the regulation of dormancy-induction and dormancy-release occur while the CBF regulon is operative in perennial,woody plants,how overexpression of CBF1 affects these dormancy-related changes in gene expression is incompletely understood.The objective of the present study was to characterize global changes in gene expression in peach CBF1-overexpressing and non-transformed apple bark tissues at different states of dormancy via RNA-seq.RNAseq bioinformatics data was confirmed by RT-qPCR on a number of genes.Results indicate that the greatest number of significantly differentially expressed genes(DEGs)occurred in April when dormancy release and bud break normally occur but are delayed in Line T166.Genes involved in storage and inactivation of auxin,GA,and cytokinin were generally upregulated in T166 in April,while those for biosynthesis,uptake or signal transduction were generally downregulated in T166.Genes for cell division and cambial growth were also downregulated in T166 relative to the non-transformed line.These data suggest that overexpression of the peach CBF1 gene impacts growth hormone homeostasis and as a result the activation of growth in the spring,and most likely growth cessation in the fall as well. | Timothy Artlip Adam McDermaid Qin Ma Michael Wisniewski | 2019 | Horticulture Research2019，6，1： | 6 |
| 8 | Alternative ventilation strategies in U.S.offices:Comprehensive assessment and sensitivity analysis of energy saving potential显示文摘Mature technologies exist to reduce the heating,ventilation,and air-conditioning(HVAC) energy associated with ventilation and use ventilation proactively to save energy.This study investigated the energy use impacts in U.S.office buildings of multiple alternative ventilation strategies that combined:economizing,demand controlled ventilation(DCV),supply air temperature reset(SR),and/or a doubled ventilation rate.We used energy simulations in a Monte Carlo analysis,sampling 17 building inputs and varying locations to match the climate zone distribution of the U.S.office stock.Results indicated the possibility for significant savings compared to a baseline that ventilated constantly at a minimum rate in both a small office type with a constant air volume(CAV) HVAC system and a medium office type with a variable air volume(VAV) system.In 95%of instances,HVAC source energy savings were 5-25%in the small-CAV office(median:11%) and 6-42%in the medium-VAV office(median:27%).In the small-CAV office,DCV typically saved the most energy,usually from heating,and heating degree days and occupant density were decisive influences.In the medium-VAV office,economizing and SR were most important,DCV usually only had minor impacts,and zone temperature setpoints,along with climate indicators,were the critical influences.Other than infiltration,envelope characteristics did not strongly influence energy impacts.The untapped primary energy savings of alternative ventilation strategies over the 74%of U.S.office floorspace reasonably represented by our modeling was estimated at 36 TWh per year,with an annual value of U.S.$ 1.25 billion. | Adams Rackes Michael S.Waring 侯恩哲 | 2017 | 建筑节能2017，45，5： | 5 |
| 9 | Executive Summary: Heart Disease and Stroke Statistics— 2010 Update: A Report From the American Heart Association显示文摘 | Donald Lloyd-Jones Robert J. Adams Todd M. Brown Mercedes Carnethon Shifan Dai Giovanni De Simone T. Bruce Ferguson Earl Ford Karen Furie Cathleen Gillespie Alan Go Kurt Greenlund Nancy Haase Susan Hailpern P. Michael Ho Virginia Howard Brett Kissela Stev | 2010 | Circulation2010，，7： | 5 |
| 10 | 《Science》杂志发表关于计算社会科学的文章:Computational Social Science显示文摘计算科学是一门正在兴起的综合性学科,它依赖于先进的计算机及计算技术对理论科学、大型实验、观测数据、应用科学、国防以及社会科学进行模型化、模拟与仿真、计算等。特别是对极复杂系统进行模型与程序化,然后利用计算机给出严格理论及实验无法达到的过程数据或者直接模拟出整个复杂过程的演变或者预测过程的发展趋势。对基础科学、应用科学、国防科学、社会科学以及工程技术等的发展有着不可估量的科学作用与经济效益。其中,随着信息化和网络化的不断普及与深入,社会动态变化的速度和规模已经提高到一个前所未有的水平,计算科学在社会科学中的深入应用,即计算社会科学也将成为科研信息化发展中一个新的热点。本刊对《Science》2009年2月发表的一篇关于计算社会科学的文章《Computational Social Science》进行了摘编,该文由美国多个大学及研究机构的共15名研究人员共同编写,文章从计算社会科学的数据获取、研究方法及其制约因素,以及人才的培养等几个方面,描述了计算社会科学的发展、讨论了社会科学研究的特点等。其主要目的是想借此文向广大读者介绍计算社会科学这一学科理念,推动这一对于提高社会科学研究水平和规范性的研究方法在国内的发展,并以此进一步繁荣我国社会科学研究工作。 | 张鉴 孔丽华 David Lazer Alex Pentland Lada Adamic Sinan Aral Albert-László Barabási Devon Brewer Nicholas Christakis Noshir Contractor James Fowler Myron Gutmann Tony Jebara Gary King Michael Macy Deb Roy Marshall Van Alstyne | 2010 | 科研信息化技术与应用2010，0，2： | 5 |
| 11 | Randomized Trial Evaluating Ranibizumab Plus Prompt or Deferred Laser or Triamcinolone Plus Prompt Laser for Diabetic Macular Edema显示文摘 | Michael J. Elman Lloyd Paul Aiello Roy W. Beck Neil M. Bressler Susan B. Bressler Allison R. Edwards Frederick L. Ferris Scott M. Friedman Adam R. Glassman Kellee M. Miller Ingrid U. Scott Cynthia R. Stockdale Jennifer K. Sun | 2010 | Ophthalmology2010，，6： | 5 |
| 12 | Nanostructured fibers as a versatile photonic platform: radiative cooling and waveguiding through transverse Anderson localization显示文摘Broadband high reflectance in nature is often the result of randomly,three-dimensionally structured materials.This study explores unique optical properties associated with one-dimensional nanostructures discovered in silk cocoon fibers of the comet moth,Argema mittrei.The fibers are populated with a high density of air voids randomly distributed across the fiber cross-section but are invariant along the fiber.These filamentary air voids strongly scatter light in the solar spectrum.A single silk fiber measuring~50μm thick can reflect 66%of incoming solar radiation,and this,together with the fibers’high emissivity of 0.88 in the mid-infrared range,allows the cocoon to act as an efficient radiative-cooling device.Drawing inspiration from these natural radiative-cooling fibers,biomimetic nanostructured fibers based on both regenerated silk fibroin and polyvinylidene difluoride are fabricated through wet spinning.Optical characterization shows that these fibers exhibit exceptional optical properties for radiative-cooling applications:nanostructured regenerated silk fibers provide a solar reflectivity of 0.73 and a thermal emissivity of 0.90,and nanostructured polyvinylidene difluoride fibers provide a solar reflectivity of 0.93 and a thermal emissivity of 0.91.The filamentary air voids lead to highly directional scattering,giving the fibers a highly reflective sheen,but more interestingly,they enable guided optical modes to propagate along the fibers through transverse Anderson localization.This discovery opens up the possibility of using wild silkmoth fibers as a biocompatible and bioresorbable material for optical signal and image transport. | Norman Nan Shi Cheng-Chia Tsai Michael J.Carter Jyotirmoy Mandal Adam C.Overvig Matthew Y.Sfeir Ming Lu Catherine L.Craig Gary D.Bernard Yuan Yang Nanfang Yu | 2018 | Light(Science & Applications)2018，7，1： | 5 |
| 13 | Detection,Occurrence,and Survey of Rice Stripe and BlackStreaked Dwarf Diseases in Zhejiang Province,China显示文摘The major viral diseases that occur on rice plants in Zhejiang Province, eastern China, are stripe and rice black-streaked dwarf diseases. Rice stripe disease is only caused by rice stripe tenuivirus(RSV), while rice black-streaked dwarf disease can be caused by rice black-streaked dwarf fijivirus(RBSDV) and/or southern rice black-streaked dwarf fijivirus(SRBSDV). Here we review the characterization of these viruses, methods for their detection, and extensive surveys showing their occurrence and spread in the province. | ZHANG Heng-mu WANG Hua-di YANG Jian Michael J ADAMS CHEN Jian-ping | 2013 | Rice science2013，20，6： | 4 |
| 14 | Posthepatectomy liver failure: A definition and grading by the International Study Group of Liver Surgery (ISGLS)显示文摘 | Nuh N. Rahbari O. James Garden Robert Padbury Mark Brooke-Smith Michael Crawford Rene Adam Moritz Koch Masatoshi Makuuchi Ronald P. Dematteo Christopher Christophi Simon Banting Val Usatoff Masato Nagino Guy Maddern Thomas J. Hugh Jean-Nicolas Vauthey Pau | 2011 | Surgery2011，，5： | 4 |
| 15 | Three-dimensional DEM-CFD analysis of air-flow-induced detachment of API particles from carrier particles in dry powder inhalers显示文摘Air flow and particle-particle/wall impacts are considered as two primary dispersion mechanisms for dry powder inhalers(DPIs).Hence,an understanding of these mechanisms is critical for the development of DPIs.In this study,a coupled DEM-CFD(discrete element method-computational fluid dynamics)is employed to investigate the influence of air flow on the dispersion performance of the carrier-based DPI formulations.A carrier-based agglomerate is initially formed and then dispersed in a uniformed air flow.It is found that air flow can drag API particles away from the carrier and those in the downstream air flow regions are prone to be dispersed.Furthermore,the influence of the air velocity and work of adhesion are also examined.It is shown that the dispersion number(i.e.,the number of API particles detached from the carrier)increases with increasing air velocity,and decreases with increasing the work of adhesion,indicating that the DPI performance is controlled by the balance of the removal and adhesive forces.It is also shown that the cumulative Weibull distribution function can be used to describe the DPI performance,which is governed by the ratio of the fluid drag force to the pull-off force. | Jiecheng Yang Chuan-Yu Wu Michael Adams | 2014 | Acta Pharmaceutica Sinica B2014，4，1： | 4 |
| 16 | Heart Disease and Stroke Statistics—2009 Update: A Report From the American Heart Association Statistics Committee and Stroke Statistics Subcommittee显示文摘 | Donald Lloyd-Jones Robert Adams Mercedes Carnethon Giovanni De Simone T Bruce Ferguson Katherine Flegal Earl Ford Karen Furie Alan Go Kurt Greenlund Nancy Haase Susan Hailpern Michael Ho Virginia Howard Brett Kissela Steven Kittner Daniel Lackland Lynda L | 2009 | Circulation2009，，3： | 4 |
| 17 | Analysis of a Successful Immune Response against Hepatitis C Virus显示文摘 | Stewart Cooper Ann L Erickson Erin J Adams Joe Kansopon Amy J Weiner David Y Chien Michael Houghton Peter Parham Christopher M Walker | 1999 | Immunity1999，，4： | 3 |
| 18 | 缺血性卒中或短暂性脑缺血发作患者的卒中预防指南显示文摘这份新声明旨在为缺血性卒中或短暂性脑缺血发作存活者的缺血性卒中预防提供全面和及时的循证推荐,循证推荐包括对危险因素的控制,动脉粥样硬化性疾病的干预措施,心源性栓塞的抗栓治疗以及非心源性卒中抗血小板药的应用。另外,还为其他多种特殊情况下复发性卒中的预防提供了推荐、包括动脉夹层分离、卵圆孔未闭、高同型半胱氨酸血症、高凝状态、镰状细胞病、脑静脉窦血栓形成、女性卒中(特别是与妊娠和绝经后激素替代治疗相关卒中),脑出血后肮凝药的应用,以及该指南在高危人群中执行和应用的特殊措施。 | Ralph L.Sacco Robert Adams Grge Albers Mark J.ALBERTS Oscar Benavente Karen Furie Larry B.Goldstein Philip Gorelick Jonathan Halperin Robert Harbaugh S.Claiborne Johnston Irene Katzan Margaret Kelly-Hayes Edgar J.Kenton Michael Marks Lee H.Schwamm Thomas Tomsick 曹勇军(译) 陈孝东(译) 毛成洁(译) 刘春风(译) | 2006 | 中华脑血管病论坛2006，4，1： | 3 |
| 19 | Adherence to acne treatment guidelines in the military environment-a descriptive,serial cross-sectional study显示文摘Background:Acne vulgaris,a common skin disease,affects up to 80% of the population.Moderate to severe acne requires treatment with a combination of topical and oral drugs such as antibiotics,hormones and retinoids.Retinoids have many contraindications and adverse effects requiring close monitoring.The study's objectives were to describe prescribing trends in acne medication over time in a military setting,and assess physician adherence to guidelines for acne treatment,including drug precautions,clinical monitoring,and treatment progression.Methods:We conducted a descriptive,serial cross-sectional study of acne drugs prescribed in the Israel Defense Forces(IDF) in the years 2002–2007,analyzing the classes of drugs prescribed and patient characteristics.In addition,the clinical quality of the medical encounter was assessed by examining physician adherence to IDF guidelines.Results:Between 2002 and 2007,64,281 patients were treated for acne.Treatment courses generally persisted for 1–2 months.Over 70% of female patients receiving oral retinoids were not concomitantly receiving oral contraceptives.Conclusions:This study provides a unique perspective of acne treatment in a military setting,overall displaying good adherence to general guidelines.The common prescription of oral retinoids to young females without concomitant contraception is alarming. | Chen Fleischmann Lior Cohen Elimelech Adams Michael Hartal | 2016 | Journal of Medical Colleges of PLA(China)2016，31，1： | 3 |
| 20 | Repeat endoscopic retrograde cholangiopancreaticography after failed initial precut sphincterotomy for biliary cannulation显示文摘AIM: To investigate the outcome of repeating endoscopic retrograde cholangiopancreaticography(ERCP) after initially failed precut sphincterotomy to achieve biliary cannulation.METHODS: In this retrospective study, consecutive ERCPs performed between January 2009 and September 2012 were included. Data from our endoscopy and radiology reporting databases were analysed for use of precut sphincterotomy, biliary access rate, repeat ERCP rate and complications. Patients with initially failed precut sphincterotomy were identified.RESULTS: From 1839 consecutive ERCPs, 187(10%) patients underwent a precut sphincterotomy during the initial ERCP in attempts to cannulate a native papilla. The initial precut was successful in 79/187(42%). ERCP was repeated in 89/108(82%) of patients with failed initial precut sphincterotomy after a median interval of 4 d, leading to successful biliary cannulation in 69/89(78%). In 5 patients a third ERCP was attempted(successful in 4 cases). Overall, repeat ERCP after failed precut at the index ERCP was successful in 73/89 patients(82%). Complications after precut-sphincterotomy were observed in 32/187(17%) patients including pancreatitis(13%), retroperitoneal perforations(1%), biliary sepsis(0.5%) and haemorrhage(3%).CONCLUSION: The high success rate of biliary cannulation in a second attempt ERCP justifies repeating ERCP within 2-7 d after unsuccessful precut sphincterotomy before more invasive approaches should be considered. | Michael Pavlides Ashley Barnabas Nilesh Fernandopulle Adam A Bailey Jane Collier Jane Phillips-Hughes Anthony Ellis Roger Chapman Barbara Braden | 2014 | World Journal of Gastroenterology2014，20，36： | 3 |
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