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| 1 | The Global Boundary Stratotype Section and Point (GSSP) for the base of the Hirnantian Stage (the uppermost of the Ordovician System)显示文摘 | Xu Chen Jiayu Rong Junxuan Fan Renbin Zhan Charles E. Mitchell David A. T. Harper Michael J. Melchin Ping'an Peng Stan C. Finney Xiaofeng Wang | 2006 | Episodes2006，29，3： | 61 |
| 2 | Elevated serum alpha fetoprotein levels promote pathological progression of hepatocellular carcinoma显示文摘AIM:To investigate the biological role of alpha fetoprotein (AFP) and its clinical signif icance in carcinogenesis of hepatocellular carcinoma (HCC).METHODS:Clinical analysis of HCC patients and im-munohistochemical examination were conducted to evaluate the relationship between serum AFP level and patient mortality. Confocal microscopy,Western blotting, dimethylthiahzolyl-2,5-diphenyl-tetrazolium bromide,Cell Counting Kit-8 assays and flow cytometry were performed to explore the possible mechanism.RESULTS: Among the 160 HCC patients enrolled in this study,130 patients survived 2 years (81.25%),with a survival rate of 86.8% in AFP < 2 0 μg/L group,88.9% in AFP 20-250 μg/L group,and 69.6% in AFP > 250 μg/L group, demonstrating a higher mortality rate in HCC patients with higher AFP levels. Surgical treatment was benef icial only in patients with low AFP levels.The mortality rate of HCC patients with high AFP levels who were treated surgically was apparently higher than those treated with conservative management.The results of immunohistochemistry showed that AFP and AFP receptor were merely expressed in tissues of HCC patients with positive serum AFP.Consistently,in vitro analysis showed that AFP and AFPS were expressed in HepG2 but not in HLE cells. AFP showed a capability to promote cell growth,and this was more apparent in HepG2 cells,in which the proliferation was increased by 3.5 folds. Cell cycle analysis showed that the percent-age of HepG2 cells in S phase after exposure to AFP was modestly increased.CONCLUSION:HCC patients with higher AFP levels show a higher mortality rate,which appears to be attributable to the growth promoting properties of AFP. | Peng Li Shan-Shan Wang Hui Liu Ning Li Michael A McNutt Gang Li Hui-Guo Ding | 2011 | World Journal of Gastroenterology2011，17，41： | 23 |
| 3 | Cold-Induced CBF–PIF3 Interaction Enhances Freezing Tolerance by Stabilizing the phyB Thermosensor in Arabidopsis显示文摘Growth inhibition and cold-acclimation strategies help plants withstand cold stress,which adversely affects growth and survival.PHYTOCHROME B(phyB)regulates plant growth through perceiving both light and ambient temperature signals.However,the mechanism by which phyB mediates the plant response to cold stress remains elusive.Here,we show that the key transcription factors mediating cold acclimation,C-REPEAT BINDING FACTORs(CBFs),interact with PHYTOCHROME-INTERACTING FACTOR 3(PIF3)under cold stress,thus attenuating the mutually assured destruction of PIF3–phyB.Cold-stabilized phyB acts downstream of CBFs to positively regulate freezing tolerance by modulating the expression of stress-responsive and growth-related genes.Consistent with this,phyB mutants exhibited a freezing-sensitive phenotype,whereas phyB-overexpression transgenic plants displayed enhanced freezing tolerance.Further analysis showed that the PIF1,PIF4,and PIF5 proteins,all of which negatively regulate plant freezing tolerance,were destabilized by cold stress in a phytochrome-dependent manner.Collectively,our study reveals that CBFs–PIF3–phyB serves as an important regulatory module for modulating plant response to cold stress. | Bochen Jiang Yiting Shi Yue Peng Yuxin Jia Yan Yan Xiaojing Dong Hui Li Jie Dong Jigang Li Zhizhong Gong Michael F.Thomashow Shuhua Yang | 2020 | Molecular Plant2020，13，6： | 13 |
| 4 | Methylated and thiolated arsenic species for environmental and health research——A review on synthesis and characterization显示文摘Hundreds of millions of people around the world are exposed to elevated concentrations of inorganic and organic arsenic compounds, increasing the risk of a wide range of health effects. Studies of the environmental fate and human health effects of arsenic require authentic arsenic compounds. We summarize here the synthesis and characterization of more than a dozen methylated and thiolated arsenic compounds that are not commercially available. We discuss the methods of synthesis for the following14 trivalent(Ⅲ) and pentavalent() arsenic compounds: monomethylarsonous acid(MMA~Ⅲ), dicysteinylmethyldithioarsenite(MMA~Ⅲ(Cys)_2), monomethylarsonic acid(MMA~Ⅴ),monomethylmonothioarsonic acid(MMMTAⅤ) or monothio-MMA~Ⅴ, monomethyldithioarsonic acid(MMDTA~Ⅴ) or dithio-MMA~Ⅴ, monomethyltrithioarsonate(MMTTA~Ⅴ) or trithio-MMA~Ⅴ,dimethylarsinous acid(DMA~Ⅲ), dimethylarsino-glutathione(DMA~Ⅲ(SG)), dimethylarsinic acid(DMA~Ⅴ), dimethylmonothioarsinic acid(DMMTA~Ⅴ) or monothio-DMAⅤ, dimethyldithioarsinic acid(DMDTA~Ⅴ) or dithio-DMA~Ⅴ, trimethylarsine oxide(TMAO~Ⅴ), arsenobetaine(AsB), and an arsenicin-A model compound. We have reviewed and compared the available methods,synthesized the arsenic compounds in our laboratories, and provided characterization information. On the basis of reaction yield, ease of synthesis and purification of product, safety considerations, and our experience, we recommend a method for the synthesis of each of these arsenic compounds. | William R.Cullen Qingqing Liu Xiufen Lu Anthony McKnight-Whitford Hanyong Peng Aleksandra Popowich Xiaowen Yan Qi Zhang Michael Fricke Hongsui Sun X.Chris Le | 2016 | Journal of Environmental Sciences2016，28，11： | 12 |
| 5 | Organ preservation: from the past to the future显示文摘机关移植是为有结束阶段疾病的病人的最有效的治疗。保藏答案和技术在移植以后与病态和幸存有关直接为施主机关质量是关键的,它是。当前,静态的冷存储(SCS ) 是为机关保藏的标准方法。然而,当延长冷存储增加贡献长期的复杂并发症的早接枝机能障碍的风险,有 SCS 的保藏时间被限制。而且,对边缘的施主机关的使用的成长要求为机关评价和修理要求方法。机器灌注在机关保藏上整修了并且统治当前的研究。它被承认到它的动态性质和象生理一样环境。更复杂的机器灌注技术和更好的 perfusates 的发展可以导致机关修理 / 修理。这评论描述机关保藏的历史,总结迄今为止被做了的进步,并且讨论为机关保藏的未来方向。 | Lei JING Leeann YAO Michael ZHAO Li-ping PENG Mingyao LIU | 2018 | Acta Pharmacologica Sinica2018，39，5： | 11 |
| 6 | Super-resolution dipole orientation mapping via polarization demodulation显示文摘Fluorescence polarization microscopy(FPM)aims to detect the dipole orientation of fluorophores and to resolve structural information for labeled organelles via wide-field or confocal microscopy.Conventional FPM often suffers from the presence of a large number of molecules within the diffraction-limited volume,with averaged fluorescence polarization collected from a group of dipoles with different orientations.Here,we apply sparse deconvolution and least-squares estimation to fluorescence polarization modulation data and demonstrate a super-resolution dipole orientation mapping(SDOM)method that resolves the effective dipole orientation from a much smaller number of fluorescent molecules within a sub-diffraction focal area.We further apply this method to resolve structural details in both fixed and live cells.For the first time,we show that different borders of a dendritic spine neck exhibit a heterogeneous distribution of dipole orientation.Furthermore,we illustrate that the dipole is always perpendicular to the direction of actin filaments in mammalian kidney cells and radially distributed in the hourglass structure of the septin protein under specific labelling.The accuracy of the dipole orientation can be further mapped using the orientation uniform factor,which shows the superiority of SDOM compared with its wide-field counterpart as the number of molecules is decreased within the smaller focal area.Using the inherent feature of the orientation dipole,the SDOM technique,with its fast imaging speed(at sub-second scale),can be applied to a broad range of fluorescently labeled biological systems to simultaneously resolve the valuable dipole orientation information with super-resolution imaging. | Karl Zhanghao Long Chen Xu-San Yang Miao-Yan Wang Zhen-Li Jing Hong-Bin Han Michael Q Zhang Dayong Jin Jun-Tao Gao Peng Xi | 2016 | Light(Science & Applications)2016，5，1： | 11 |
| 7 | Hsa-miR-1246, hsa-miR-320a and hsa-miR-196b-5p inhibitors can reduce the cytotoxicity of Ebola virus glycoprotein in vitro显示文摘Ebola virus(EBOV)causes a highly lethal hemorrhagic fever syndrome in humans and has been associated with mortality rates of up to 91%in Zaire,the most lethal strain.Though the viral envelope glycoprotein(GP)mediates widespread inflammation and cellular damage,these changes have mainly focused on alterations at the protein level,the role of microRNAs(miRNAs)in the molecular pathogenesis underlying this lethal disease is not fully understood.Here,we report that the miRNAs hsa-miR-1246,hsa-miR-320a and hsa-miR-196b-5p were induced in human umbilical vein endothelial cells(HUVECs)following expression of EBOV GP.Among the proteins encoded by predicted targets of these miRNAs,the adhesion-related molecules tissue factor pathway inhibitor(TFPI),dystroglycan1(DAG1)and the caspase 8 and FADD-like apoptosis regulator(CFLAR)were significantly downregulated in EBOV GP-expressing HUVECs.Moreover,inhibition of hsa-miR-1246,hsa-miR-320a and hsa-miR-196b-5p,or overexpression of TFPI,DAG1 and CFLAR rescued the cell viability that was induced by EBOV GP.Our results provide a novel molecular basis for EBOV pathogenesis and may contribute to the development of strategies to protect against future EBOV pandemics. | SHENG MiaoMiao ZHONG Ying CHEN Yang DU JianChao JU XiangWu ZHAO Chen ZHANG GuiGen ZHANG LiFang LIU KangTai YANG Ning XIE Peng LI DangSheng ZHANG Michael Q. JIANG ChengYu | 2014 | Science China(Life Sciences)2014，57，10： | 7 |
| 8 | K-ras^G12V transformation leads to mitochondrial dysfunction and a metabolic switch from oxidative phosphorylation to glycolysis显示文摘增加的氧气的 glycolysis 和氧化应力是癌症房间新陈代谢的重要特征,但是内在的生物化学、分子的机制留下逃犯。用四圜素可诱导的模型,我们显示出 K 地岬 G12V 原因 mitochondrial 机能障碍,导致反应的氧的减少的呼吸,提高的 glycolysis,和增加的产生种类。K 地岬蛋白质与线粒体被联系,并且导致呼吸的链建筑群的快速的抑制 -- 我和在由影响 cyclosporin 敏感的渗透的 mitochondrial transmembrane 潜力的减少转移毛孔。而且, K 地岬 在 vitro 的 G12V 表示提高转变房间的能力允许新陈代谢的改编到高 glycolytic 新陈代谢在 vivo 形成肿瘤。我们的学习建议 mitochondrial 机能障碍的那正式就职是由 K 地岬 G12V 在癌症房间引起新陈代谢的变化和 ROS 应力,并且支持肿瘤开发。 | Yumin Hu Weiqin Lu Gang Chen Peng Wang Zhao Chen Yan Zhou Marcia Ogasawara Dunyaporn Trachootham Li Feng Helene Pelicano Paul J Chiao Michael J Keating Guillermo Garcia-Manero Peng Huang | 2012 | Cell Research2012，22，2： | 6 |
| 9 | Energy Efficient Run-Time Incremental Mapping for 3-D Networks-on-Chip显示文摘3-D Networks-on-Chip(NoC) emerge as a potent solution to address both the interconnection and design complexity problems facing future Multiprocessor System-on-Chips(MPSoCs).Effective run-time mapping on such 3-D NoC-based MPSoCs can be quite challenging,as the arrival order and task graphs of the target applications are typically not known a priori,which can be further complicated by stringent energy requirements for NoC systems.This paper thus presents an energy-aware run-time incremental mapping algorithm(ERIM) for 3-D NoC which can minimize the energy consumption due to the data communications among processor cores,while reducing the fragmentation effect on the incoming applications to be mapped,and simultaneously satisfying the thermal constraints imposed on each incoming application.Specifically,incoming applications are mapped to cuboid tile regions for lower energy consumption of communication and the minimal routing.Fragment tiles due to system fragmentation can be gleaned for better resource utilization.Extensive experiments have been conducted to evaluate the performance of the proposed algorithm ERIM,and the results are compared against the optimal mapping algorithm(branch-and-bound) and two heuristic algorithms(TB and TL).The experiments show that ERIM outperforms TB and TL methods with significant energy saving(more than 10%),much reduced average response time,and improved system utilization. | Xiao-Hang Wang Peng Liu Mei Yang Maurizio Palesi Ying-Tao Jiang Michael C Huang | 2013 | Journal of Computer Science & Technology2013，28，1： | 5 |
| 10 | Consumption of rice and fish in an electronic waste recycling area contributes significantly to total daily intake of mercury显示文摘Mercury is a global pollutant due to its widespread use,emission,and long-range transport(Blum,2013;Pacyna et al.,2010).It is considered a priority pollutant due to its neurological toxicity,persistence,and bioaccumulation(Pacyna et al.,2010;Sharma et al.,2015).Mercury pollution can occur when products that contain mercury are improperly disposed of and mercury is released into the air,water,and soil(Zhang and Wong,2007).An estimated 22%of the annual world usage of mercury is in electrical equipment such as batteries,thermometers,and discharge lamps,and electronic devices such as monitors | Hanyong Peng Michael S.Reid X.Chris Le | 2015 | Journal of Environmental Sciences2015，27，12： | 5 |
| 11 | Doped, conductive SiO_(2) nanoparticles for large microwave absorption显示文摘Although many materials have been studied for the purpose of microwave absorption,SiO_(2) has never been reported as a good candidate.In this study,we present for the first time that doped,microwave conductive SiO_(2) nanoparticles can possess an excellent microwave absorbing performance.A large microwave reflection loss(RL)of−55.09 dB can be obtained.The large microwave absorption originates mainly from electrical relaxation rather than the magnetic relaxation of the incoming microwave field.The electrical relaxation is attributed to a large electrical conductivity that is enabled by the incorporation of heterogeneous(N,C and Cl)atoms.The removal of the magnetic susceptibility only results in a negligible influence of the microwave absorption.In contrast,the removal of the heterogeneous atoms leads to a large decrease in the electrical conductivity and microwave absorption performance.Meanwhile,the microwave absorption characteristics can be largely adjusted with a change of the thickness,which provides large flexibility for various microwave absorption applications. | Michael Green Zhanqiang Liu Peng Xiang Yan Liu Minjie Zhou Xinyu Tan Fuqiang Huang Lei Liu Xiaobo Chen | 2018 | Light(Science & Applications)2018，7，1： | 4 |
| 12 | Key changes in denervated muscles and their impact on regeneration and reinnervation显示文摘The neuromuscular junction becomes progressively less receptive to regenerating axons if nerve repair is delayed for a long period of time.It is difficult to ascertain the denervated muscle's residual receptivity by time alone.Other sensitive markers that closely correlate with the extent of denervation should be found.After a denervated muscle develops a fibrillation potential,muscle fiber conduction velocity,muscle fiber diameter,muscle wet weight,and maximal isometric force all decrease; remodeling increases neuromuscular junction fragmentation and plantar area,and expression of myogenesis-related genes is initially up-regulated and then down-regulated.All these changes correlate with both the time course and degree of denervation.The nature and time course of these denervation changes in muscle are reviewed from the literature to explore their roles in assessing both the degree of detrimental changes and the potential success of a nerve repair.Fibrillation potential amplitude,muscle fiber conduction velocity,muscle fiber diameter,m RNA expression levels of myogenic regulatory factors and nicotinic acetylcholine receptor could all reflect the severity and length of denervation and the receptiveness of denervated muscle to regenerating axons,which could possibly offer an important clue for surgical choices and predict the outcomes of delayed nerve repair. | Peng Wu Aditya Chawla Robert J.Spinner Cong Yu Michael J.Yaszemski Anthony J.Windebank Huan Wang | 2014 | Neural Regeneration Research2014，9，20： | 3 |
| 13 | Biodegradable magnesium pins enhanced the healing of transverse patellar fracture in rabbits显示文摘Displaced fractures of patella often require open reduction surgery and internal fixation to restore the extensor continuity and articular congruity.Fracture fixation with biodegradable magnesium(Mg)pins enhanced fracture healing.We hypothesized that fixation with Mg pins and their degradation over time would enhance healing of patellar fracture radiologically,mechanically,and histologically.Transverse patellar fracture surgery was performed on thirty-two 18-weeks old female New Zealand White Rabbits.The fracture was fixed with a pin made of stainless steel or pure Mg,and a figure-of-eight stainless steel band wire.Samples were harvested at week 8 or 12,and assessed with microCT,tensile testing,microindentation,and histology.Microarchitectural analysis showed that Mg group showed 12%higher in the ratio of bone volume to tissue volume at week 8,and 38.4%higher of bone volume at week 12.Tensile testing showed that the failure load and stiffness of Mg group were 66.9%and 104%higher than the control group at week 8,respectively.At week 12,Mg group was 60.8%higher in ultimate strength than the control group.Microindentation showed that,compared to the Control group,Mg group showed 49.9%higher Vickers hardness and 31%higher elastic modulus at week 8 and 12,respectively.At week 12,the new bone of Mg group remodelled to laminar bone,but those of the control group remained woven bone-like.Fixation of transverse patellar fracture with Mg pins and its degradation enhanced new bone formation and mechanical properties of the repaired patella compared to the Control group. | Dick Ho Kiu Chow Jiali Wang Peng Wan Lizhen Zheng Michael Tim Yun Ong Le Huang Wenxue Tong Lili Tan Ke Yang Ling Qin | 2021 | Bioactive Materials2021，6，11： | 3 |
| 14 | Level set band method: A combination of density-based and level set methods for the topology optimization of continuums显示文摘The level set method(LSM),which is transplanted from the computer graphics field,has been successfully introduced into the structural topology optimization field for about two decades,but it still has not been widely applied to practical engineering problems as density-based methods do.One of the reasons is that it acts as a boundary evolution algorithm,which is not as flexible as density-based methods at controlling topology changes.In this study,a level set band method is proposed to overcome this drawback in handling topology changes in the level set framework.This scheme is proposed to improve the continuity of objective and constraint functions by incorporating one parameter,namely,level set band,to seamlessly combine LSM and density-based method to utilize their advantages.The proposed method demonstrates a flexible topology change by applying a certain size of the level set band and can converge to a clear boundary representation methodology.The method is easy to implement for improving existing LSMs and does not require the introduction of penalization or filtering factors that are prone to numerical issues.Several 2D and 3D numerical examples of compliance minimization problems are studied to illustrate the effects of the proposed method. | Peng WEI Wenwen WANG Yang YANG Michael Yu WANG | 2020 | Frontiers of Mechanical Engineering2020，15，3： | 3 |
| 15 | Synthesis, Crystal Structure and Calculated β Value of a Tetrahedral Zinc (II) Complex——Zn(2-NH_2py)_2Br_2显示文摘A new zinc(II) complex, Zn(2-NH2py)2Br2 (py=pyridine), has been synthesized, and its molecular structure has been confirmed by IR, elemental analysis and -ray crystal structure analysis. Its space group is P21/n with Mr=413.43 (C10H12Br2N4Zn), a=7.435(2), b=12.865(3), c=14.186(4)? b=94.08(2)? V=1353.5(5) 3, Z=4, Dc=2.029 g/cm3, F(000)=328, ?2.378mm-1, R=0.0283, wR=0.0501. The total observed reflections with I≥2?I) were 5314, of which the independent reflections were 3106. The complex structure contains a distorted tetrahedron formed by four atoms coordinated to zinc atom, namely two bromide atoms and two nitrogen atoms. The two ZnBr bond lengths within one molecule, 2.3763(6) and 2.4002(5)? respectively, are not equal; and so are the two ZnN bond lengths, which are 2.031(2) and 2.044(2)?respectively. The calculation results using PM3 method through MOPAC software package in Chem 3D show that its first molecular hyperpolarizability b value is 5.210-30esu, which is comparable with that of p-nitroaniline. No bulk SHG effect has been detected due to the centrosymmetric space group. | REN Peng a SU Nan-Bing a QIN Jin-Gui a Michael W. Day b CHEN Chuang-Tianc ( aDepartment of Chemistry, Wuhan University, Wuhan 43007, China) ( bBeckman Institute, California Institute of Technology, Pasadena, CA91125, USAQ ) ( cBeijing R & D Center | 2002 | Chinese Journal of Structural Chemistry2002，21，1： | 3 |
| 16 | Mesencephalic astrocyte-derived neurotrophic factor ameliorates steatosis in HepG2 cells by regulating hepatic lipid metabolism显示文摘BACKGROUND Nonalcoholic fatty liver disease (NAFLD) is a global metabolism-associated liver disease.Mesencephalic astrocyte-derived neurotrophic factor (MANF) is a newly discovered secreted protein that is involved in metabolic homeostasis.However,much remains to be discovered about its function in hepatic lipid metabolism;thus,we assessed whether MANF could regulate hepatic metabolism.AIM To establish in vivo and in vitro NAFLD models to explore the role of MANF in hepatic lipid metabolism.METHODS HepG2 cells treated with free fatty acids (FFAs) and ob/ob mice were used as NAFLD models.Liver tissues collected from wild type and ob/ob mice were used to detect MANF expression.Cells were treated with FFAs for different durations.Moreover,we used lentiviral constructs to establish overexpression and knockdown cell models in order to interfere with MANF expression levels and observe whether MANF influences hepatic steatosis.Western blot analysis and quantitative real-time PCR were used to detect protein and gene expression,and oil red O staining was used to visualize intracellular lipid droplets.RESULTS Hepatic MANF protein and mRNA expression in wild type mice were 10-fold and 2-fold higher,respectively,than those in ob/ob mice.The MANF protein was temporarily increased by 1.3-fold after stimulation with FFAs for 24 h and gradually decreased to 0.66-fold that of the control at the 72 h time point in HepG2 cells.MANF deficiency upregulated the expression of genes involved infatty acid synthesis,cholesterol synthesis,and fatty acid uptake and aggravated HepG2 cell steatosis,while MANF overexpression inhibited fatty acid synthesis and uptake and cholesterol synthesis,and rescued HepG2 cells from FFAsinduced steatosis.Furthermore,a significant decrease in triglyceride levels was observed in the MANF overexpression group compared with the control group(0.4288±0.0081 mmol/g vs 0.3746±0.0121 mmol/g,P <0.05) upon FF As treatment.There was also a 17%decrease in intracellular total cholesterol levels between the MANF overexpression group and the control group (0.1301±0.0059mmol/g vs 0.1088±0.0009 mmol/g,P <0.05) upon FF As treatment.Moreover,MANF suppressed lipid deposition in HepG2 cells.CONCLUSION Our findings indicate that MANF improves the phenotype of liver cell steatosis and may be a potential therapeutic target in hepatic steatosis processes. | Miao He Cong Wang Xiao-Hong Long Jia-Jia Peng Dong-Fang Liu Gang-Yi Yang Michael D Jensen Li-Li Zhang | 2020 | World Journal of Gastroenterology2020，26，10： | 3 |
| 17 | Microwave absorption of aluminum/hydrogen treated titanium dioxide nanoparticles显示文摘Interactions between incident electromagnetic energy and matter are of critical importance for numerous civil and military applications such as photocatalysis,solar cells,optics,radar detection,communications,information processing and transport et al.Traditional mechanisms for such interactions in the microwave frequency mainly rely on dipole rotations and magnetic domain resonance.In this study,we present the first report of the microwave absorption of Al/H2 treated TiO_(2) nanoparticles,where the A_(l)/H_(2) treatment not only induces structural and optical property changes,but also largely improves the microwave absorption performance of TiO_(2) nanoparticles.Moreover,the frequency of the microwave absorption can be finely controlled with the treatment temperature,and the absorption efficiency can reach optimal values with a careful temperature tuning.A large reflection loss of58.02 dB has been demonstrated with 3.1mm TiO_(2) coating when the treating temperature is 700℃.The high efficiency of microwave absorption is most likely linked to the disordering-induced property changes in the materials.Along with the increased microwave absorption properties are largely increased visiblelight and IR absorptions,and enhanced electrical conductivity and reduced skin-depth,which is likely related to the interfacial defects within the TiO_(2) nanoparticles caused by the Al/H2 treatment. | Michael Green Peng Xiang Zhanqiang Liu James Murowchick Xinyu Tan Fuqiang Huang Xiaobo Chen | 2019 | Journal of Materiomics2019，5，1： | 3 |
| 18 | Effects of Mechanical Milling and Sintering Temperature on the Densification, Microstructure and Tensile Properties of the Fe–Mn–Si Powder Compacts显示文摘This work reported on the effects of mechanical milling and sintering temperature on the densification,microstructure and mechanical properties of the Fe–28Mn–3Si(wt%) alloy. Elemental Fe, Mn and Si powders were used as the starting materials, and two batches of powder mixture were prepared: one was blended elemental(BE) powder mixture; the other was mechanically milled(MM) powder mixture milled for5 h using planetary ball milling. Both powder mixtures were pressed under a uniaxial pressure of 400 MPa,and subsequently sintered in a high vacuum furnace for 3 h at 1000, 1100, 1200 and 1300 °C. It was found that Mn depletion region(MDR) was formed on the surface of all the sintered samples. The sintered BE compacts had a low density(<68.2%) at all temperatures, while the density of the sintered MM compacts increased drastically from ~65% at 1000 °C to ~91% at 1300 °C. All the sintered MM compacts were composed of a predominant γ-austenite and minor ε-martensite. In comparison, additional(Fe, Mn)3Si phase was observed in the BE alloys sintered at 1000 °C, and a single α-Fe phase was identified in the BE compact sintered at 1300 °C. The tensile properties of the sintered MM compacts increased significantly with the temperature and were significantly higher than those of their BE counterparts. | Zhigang Xu Michael A.Hodgson Peng Cao | 2016 | Journal of Materials Science & Technology2016，32，11： | 3 |
| 19 | Development of a panel of unigene-derived polymorphic EST–SSR markers in lentil using public database information显示文摘Lentil(Lens culinaris Medik.), a diploid(2n = 14) with a genome size greater than 4000 Mbp, is an important cool season food legume grown worldwide. The availability of genomic resources is limited in this crop species. The objective of this study was to develop polymorphic markers in lentil using publicly available curated expressed sequence tag information(ESTs). In this study, 9513 ESTs were downloaded from the National Center for Biotechnology Information(NCBI) database to develop unigene-based simple sequence repeat(SSR) markers. The ESTs were assembled into 4053 unigenes and then analyzed to identify 374 SSRs using the MISA microsatellite identification tool. Among the 374 SSRs, 26 compound SSRs were observed.Primer pairs for these SSRs were designed using Primer3 version 1.14. To classify the functional annotation of ESTs and EST–SSRs, BLASTx searches(using E-value 1 × 10-5) against the public UniP rot(http://gffzzc0d2db89b939488bhxv9b6qb5xknp6xcw.ffgz.tsg.suse.edu.cn/) and NCBI(http://gffzz5b533c64939a43b3hxv9b6qb5xknp6xcw.ffgz.tsg.suse.edu.cn/) databases were performed. Further functional annotation was performed using PLAZA(version3.0) comparative genomics and GO annotation was summarized using the Plant GO slim category. Among the synthesized 312 primers, 219 successfully amplified Lens DNA. A diverse panel of 24 Lens genotypes was used to identify polymorphic markers. A polymorphic set of 57 markers successfully discriminated the test genotypes. This set of polymorphic markers with functional annotation data could be used as molecular tools in lentil breeding. | Debjyoti Sen Gupta Peng Cheng Gaurav Sablok Dil Thavarajah Pushparajah Thavarajah Clarice J.Coyne Shiv Kumar Michael Baum Rebecca J.McGee | 2016 | The Crop Journal2016，4，5： | 2 |
| 20 | Simulating global soil-CO_2 flux and its response to climate change显示文摘It has been argued that increased soil respiration would become a major atmospheric source of CO\-2 in the event of global warming. The simple statistical models were developed based on a georeferenced database with 0 5°×0 5° longitude/latitude resolution to simulate global soil\|CO\-2 fluxes, to investigate climatic effects on these fluxes using sensitivity experiments, and to assess possible responses of soil\|CO\-2 fluxes to various climate change scenarios. The statistical models yield a value of 69 PgC/a of global soil\|CO\-2 fluxes for current condition. Sensitivity experiments confirm that the fluxes are responsive to changes in temperature, precipitation and actual evapotranspiration, but increases in temperature and actual evapotranspiration affect soil\|CO 2 fluxes more than increases in precipitation. Using climatic change projections from four global circulation models, each corresponding to an equilibrium doubling of CO 2, it can be found that the largest increases in soil\|CO 2 fluxes were associated with the boreal and tundra regions. The globally averaged soil\|CO 2 fluxes were estimated to increase by about 35% above current values, providing a positive feedback to the greenhouse effect. | PENG Chang\|hui 1* , Michael J. Apps\+2 (1 Ontario Forest Research Institute, Ministry of Natural Resources, 1235 Queen Street East, Sault Ste. Marie, ON P6A 2E5,Canada. E\|mail: pengc@gov.on.ca 2 Morthern Forestry Center, Canadian Forest Serv | 2000 | Journal of Environmental Sciences2000，12，3： | 2 |
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