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20篇 您的检索式:作者名="Pablo LE"
    题名 作者 年代 出处 被引量
1Effect of damaged starch levels on flour-thermal behaviour and bread staling显示文摘Alberto E. León Gabriela N. Barrera Gabriela T. Pérez Pablo D. Ribotta Cristina M. Rosell 2006European Food Research and Technology2006,,2:1
2Mapping standard automated perimetry to the peripapillary retinal nerve fiber layer in glaucoma显示文摘Ferreras A Pablo LE Garway-Heath DF 2008Invest Ophthalmnl Vis Sci2008,49,:1
3Influence of soy protein on rheological properties and water retention capacity of wheat gluten显示文摘Paola Roccia Pablo D. Ribotta Gabriela T. Pérez Alberto Edel León 2008LWT - Food Science and Technology2008,,1:1
4Laparoscopic approach to esophageal perforation secondary to pneumatic dilation for achalasia显示文摘Andrés Sánchez-Pernaute Elia Pérez Aguirre Pablo Talavera Luis Díez Valladares Julio Pérez Serna Concepción Sevilla Mantilla Antonio Ruiz León Antonio Torres 2009Surgical Endoscopy2009,,5:1
5Relationship between standard automated perimetry and retinalnerve fiber layer parameters obtained with optical coherencetomography显示文摘Lopez-Pena MJ Ferreras A Larrosa JM Vicente PM Pablo LE 2011J Glaucoma2011,20,42:1
6Mapping standard automated perimetry to the peripapillary retinal nerve fiber layer in glaucoma显示文摘Ferreras A Pablo LE Garway-Heath DF 2008Invest Ophthalmol Vis Sei2008,49,:1
7Role of formyl peptide receptor-like 1 (FPRL1/FPR2) in mononuclear phagocyte responses in alzheimer disease显示文摘Pablo Iribarren Ye Zhou Jinyue Hu Yingying Le Ji Ming Wang 2005Immunologic Research2005,,3:1
8Short-wavelength automated perimetry (SWAP) in subjects with suspected glaucoma (I) :assessment of sensitivity thresholds 显示文摘Polo Llorens V Pinilla Lozano I Pablo Julvez LE 2000Arch Soc Esp Oftalmol2000,75,:1
9Discriminating between normal and glaucoma-damaged eyes with the Heidelberg Retina Tomograph 3显示文摘Ferreras A Pablo LE Larrosa JM 2008Ophthalmology2008,115,5:1
10Diagnostic ability of the Heidelberg retina tomography,opti-cal coherence tomography,and scanning laser polarimeter in open angle glaucoma显示文摘Pueyo V Polo V Larrosa JM Ferreras A Pablo LE Honrubia FM 2007J Glaucoma2007,16,2:1
11Short-wavelength automated perimetry and retinal nerve fiber layer evaluation in suspected cases of glaucoma 显示文摘Polo V Abecia E Pablo LE 1998Arch Ophthalmol1998,116,:1
12Role of formyl peptide receptor-like 1 (FPRL1/FPR2) in mononuclear phagocyte responses in alzheimer disease显示文摘Pablo Iribarren Ye Zhou Jinyue Hu Yingying Le Ji Ming Wang 2005Immunologic Research2005,,3:1
13Mapping standard automated perimetry to the peripapillary retinal nerve fiber layer in glaucoma显示文摘Ferreras A Pablo LE Garway-Heath DF 2008Invest Ophtalmol Vis Sci2008,49,7:1
14Quantifying SERS enhancements显示文摘Eric C. Le Ru Pablo G. Etchegoin 2013MRS Bulletin2013,,8:1
15Enzymatic recycling-based amperometric immunosensor for the ultrasensitive detection of okadaic acid in shellfish显示文摘Mònica Campàs Pablo de la Iglesia Marie Le Berre Marian Kane Jorge Diogène Jean-Louis Marty 2008Biosensors and Bioelectronics2008,,4:1
16Influence of damaged starch on cookie and bread-making quality显示文摘Gabriela N. Barrera Gabriela T. Pérez Pablo D. Ribotta Alberto E. León 2007European Food Research and Technology2007,,1:1
17Garlic:Medicinal Plant and Natural Aromatic Condiment显示文摘Objective:To relate the presence of active metabolites with therapeutic effects of the Allium sativum L whose common name is Garlic,as well as its contraindications and adverse reactions and its use as condiment.Methods:Searching about the topic in the last 5 years and present a general view of the Allium sativum L whose common name is Garlic.Conclusions:Technological prevision was based on the search of articles in the Virtual Library in Health(BVS)and using the key words“medicinal plants”/“spice”/Allium sativum L/garlic/adverse reactions and contraindications,and the association among them.Alexis Ruiz León Regina de Caridad Rodríguez Muñoz Ana Elena Rodríguez Cadalso Luis Pablo Ibáñez Silva Eduardo RafaelÁguila Turiño Lesvia Leonides Rodríguez Galdó Úrsula Cristina Pomares Ortega 2021Journal of Pharmacy and Pharmacology2021,9,12:0
18Decline in subarachnoid haemorrhage volumes associated with the first wave of the COVID- 19 pandemic显示文摘Background During the COVID-19 pandemic,decreased volumes of stroke admissions and mechanical thrombectomy were reported.The study’s objective was to examine whether subarachnoid haemorrhage(SAH)hospitalisations and ruptured aneurysm coiling interventions demonstrated similar declines.Methods We conducted a cross-sectional,retrospective,observational study across 6 continents,37 countries and 140 comprehensive stroke centres.Patients with the diagnosis of SAH,aneurysmal SAH,ruptured aneurysm coiling interventions and COVID-19 were identified by prospective aneurysm databases or by International Classification of Diseases,10th Revision,codes.The 3-month cumulative volume,monthly volumes for SAH hospitalisations and ruptured aneurysm coiling procedures were compared for the period before(1 year and immediately before)and during the pandemic,defined as 1 March-31 May 2020.The prior 1-year control period(1 March-31 May 2019)was obtained to account for seasonal variation.Findings There was a significant decline in SAH hospitalisations,with 2044 admissions in the 3 months immediately before and 1585 admissions during the pandemic,representing a relative decline of 22.5%(95%CI−24.3%to−20.7%,p<0.0001).Embolisation of ruptured aneurysms declined with 1170-1035 procedures,respectively,representing an 11.5%(95%CI−13.5%to−9.8%,p=0.002)relative drop.Subgroup analysis was noted for aneurysmal SAH hospitalisation decline from 834 to 626 hospitalisations,a 24.9%relative decline(95%CI−28.0%to−22.1%,p<0.0001).A relative increase in ruptured aneurysm coiling was noted in low coiling volume hospitals of 41.1%(95%CI 32.3%to 50.6%,p=0.008)despite a decrease in SAH admissions in this tertile.Interpretation There was a relative decrease in the volume of SAH hospitalisations,aneurysmal SAH hospitalisations and ruptured aneurysm embolisations during the COVID-19 pandemic.These findings in SAH are consistent with a decrease in other emergencies,such as stroke and myocardial infarction.Thanh N Nguyen Diogo C Haussen Muhammad M Qureshi Hiroshi Yamagami Toshiyuki Fujinaka Ossama Y Mansour Mohamad Abdalkader Michael Frankel Zhongming Qiu Allan Taylor Pedro Lylyk Omer F Eker Laura Mechtouff Michel Piotin Fabricio Oliveira Lima Francisco Mont'Alverne Wazim Izzath Nobuyuki Sakai Mahmoud Mohammaden Alhamza R Al-Bayati Leonardo Renieri Salvatore Mangiafico David Ozretic Vanessa Chalumeau Saima Ahmad Umair Rashid Syed Irteza Hussain Seby John Emma Griffin John Thornton Jose Antonio Fiorot Rodrigo Rivera Nadia Hammami Anna M Cervantes-Arslanian Hormuzdiyar H Dasenbrock Huynh Le Vu Viet Quy Nguyen Steven Hetts Romain Bourcier Romain Guile Melanie Walker Malveeka Sharma Don Frei Pascal Jabbour Nabeel Herial Fawaz Al-Mufti Atilla Ozcan Ozdemir Ozlem Aykac Dheeraj Gandhi Chandril Chugh Charles Matouk Pascale Lavoie Randall Edgell Andre Beer-Furlan Michael Chen Monika Killer-Oberpfalzer Vitor Mendes Pereira Patrick Nicholson Vikram Huded Nobuyuki Ohara Daisuke Watanabe Dong Hun Shin Pedro SC Magalhaes Raghid Kikano Santiago Ortega-Gutierrez Mudassir Farooqui Amal Abou-Hamden Tatsuo Amano Ryoo Yamamoto Adrienne Weeks Elena A Cora Rotem Sivan-Hoffmann Roberto Crosa Markus Möhlenbruch Simon Nagel Hosam Al-Jehani Sunil A Sheth Victor S Lopez Rivera James E Siegler Achmad Fidaus Sani Ajit S Puri Anna Luisa Kuhn Gianmarco Bernava Paolo Machi Daniel G Abud Octavio M Pontes-Neto Ajay K Wakhloo Barbara Voetsch Eytan Raz Shadi Yaghi Brijesh P Mehta Naoto Kimura Mamoru Murakami Jin Soo Lee Ji Man Hong Robert Fahed Gregory Walker Eiji Hagashi Steve M Cordina Hong Gee Roh Ken Wong Juan F Arenillas Mario Martinez-Galdamez Jordi Blasco Alejandro Rodriguez Vasquez Luisa Fonseca M Luis Silva Teddy Y Wu Simon John Alex Brehm Marios Psychogios William J Mack Matthew Tenser Tatemi Todaka Miki Fujimura Roberta Novakovic Jun Deguchi Yuri Sugiura Hiroshi Tokimura Rakesh Khatri Michael Kelly Lissa Peeling Yuichi Murayama Hugh Stephen Winters Johnny Wong Mohamed Teleb Jeremy Payne Hiroki Fukuda Kosuke Miyake Junsuke Shimbo Yusuke Sugimura Masaaki Uno Yohei Takenobu Yuji Matsumaru Satoshi Yamada Ryuhei Kono Takuya Kanamaru Masafumi Morimoto Junichi Iida Vasu Saini Dileep Yavagal Saif Bushnaq Wenguo Huang Italo Linfante Jawad Kirmani David S Liebeskind Viktor Szeder Ruchir Shah Thomas G Devlin Lee Birnbaum Jun Luo Anchalee Churojana Hesham E Masoud Carlos Ynigo Lopez Brendan Steinfort Alice Ma Ameer E Hassan Amal Al Hashmi Mollie McDermott Maxim Mokin Alex Chebl Odysseas Kargiotis Georgios Tsivgoulis Jane G Morris Clifford J Eskey Jesse Thon Leticia Rebello Dorothea Altschul Oriana Cornett Varsha Singh Jeyaraj Pandian Anirudh Kulkarni Pablo M Lavados Veronica V Olavarria Kenichi Todo Yuki Yamamoto Gisele Sampaio Silva Serdar Geyik Jasmine Johann Sumeet Multani Artem Kaliaev Kazutaka Sonoda Hiroyuki Hashimoto Adel Alhazzani David Y Chung Stephan A Mayer Johanna T Fifi Michael D Hill Hao Zhang Zhengzhou Yuan Xianjin Shang Alicia C Castonguay Rishi Gupta Tudor G Jovin Jean Raymond Osama O Zaidat Raul G Nogueira SVIN COVID-19 Registry,the Middle East North Africa Stroke and Interventional Neurotherapies Organization(MENA-SINO),Japanese Society of Vascular and Interventional Neurology Society(JVIN) 2021Stroke & Vascular Neurology2021,6,4:0
19Helicobacter pylori HopE and HopV porins present scarce expression among clinical isolates显示文摘AIM:To evaluate how widely Helicobacter pylori (H. pylori ) HopE and HopV porins are expressed among Chilean isolates and how seroprevalent they are among infected patients in Chile.METHODS: H. pylori hopE and hopV genes derived from strain CHCTX-1 were cloned by polymerase chain reaction (PCR), sequenced and expressed in Escherichia coli AD494 (DE3). Gel-purified porins were used to prepare polyclonal antibodies. The presence of both genes was tested by PCR in a collection of H. pylori clinical isolates and their expression was detected in lysates by immunoblotting. Immune responses against HopE, HopV and other H. pylori antigens in sera from infected and non-infected patients were tested by Western blotting using these sera as f irst antibody on recombinant H. pylori antigens.RESULTS: PCR and Western blotting assays revealed that 60 and 82 out of 130 Chilean isolates carried hopE and hopV genes, respectively, but only 16 and 9, respectively, expressed these porins. IgG serum immunoreactivity evaluation of 69 H. pylori-infected patients revealed that HopE and HopV were infrequently recognized (8.7% and 10.1% respectively) compared to H. pylori VacA (68.1%) and CagA (59.5%) antigens. Similar values were detected for IgA serum immunoreactivity against HopE (11.6%) and HopV (10.5%) although lower values for VacA (42%) and CagA (17.4%) were obtained when compared to the IgG response.CONCLUSION: A scarce expression of HopE and HopV among Chilean isolates was found, in agreement with the infrequent seroconversion against these antigens when tested in infected Chilean patients.Maritza Lienlaf Juan Pablo Morales María Inés Díaz Rodrigo Díaz Elsa Bruce Freddy Siegel Gloria León Paul R Harris Alejandro Venegas 2010World Journal of Gastroenterology2010,16,3:0
20A Th2-score in the tumor microenvironment as a predictive biomarker of response to Bacillus Calmette Guérin in patients with non-muscle invasive bladder carcinoma:A retrospective study显示文摘Intravesical Bacillus Calmette Guerin(BCG)is the gold standard therapy for intermediate/high-risk nonmuscle invasive bladder cancer(NMIBC).However,the response rate is~60%,and 50%of non-responders will progress to muscle-invasive disease.BCG induces massive local infiltration of inflammatory cells(Th1)and ultimately cytotoxic tumor elimination.We searched for predictive biomarker of BCG response by analyzing tumor-infiltrating lymphocyte(TIL)polarization in the tumor microenvironment(TME)in pre-treatment biopsies.Pre-treatment biopsies from patients with NMIBC who received adequate intravesical instillation of BCG(n=32)were evaluated retrospectively by immunohistochemistry.TME polarization was assessed by quantifying the T-Bet+(Th1)and GATA-3+(Th2)lymphocyte ratio(G/T),and the density and degranulation of EPX+eosinophils.In addition,PD-1/PD-L1 staining was quantified.The results correlated with BCG response.In most non-responders,Th1/Th2 markers were compared in pre-and post-BCG biopsies.ORR was 65.6%in the study population.BCG responders had a higher G/T ratio and a greater number of degranulated EPX+cells.Variables combined into a Th2-score showed a significant association with higher scores in responders(p=0.027).A Th2-score cut-off value>48.1 allowed discrimination of responders with 91%sensitivity but lower specificity.Relapse-free survival was significantly associated with the Th2-score(p=0.007).In post-BCG biopsies from recurring patients,TILs increased Th2-polarization,probably reflecting BCG failure to induce a pro-inflammatory status and,thus,a lack of response.PD-L1/PD-1 expression was not associated with the response to BCG.Our results support the hypothesis that a preexisting Th2-polarized TME predicts a better response to BCG,assuming a reversion to Th1 polarization and antitumor activity.GUSTAVO MARTÍN VILLOLDO MARÍA TERESA POMBO MARIANA ARIS JOAQUÍN CHEMI PABLO MANDÓ SUPRIYA NAGARAJU JUAN CAMEAN ADRIÁN BURIONI DEBORAH EGEA MORA AMAT JOSÉLEÓN MELLADO JOSÉMORDOH ALBERTO VILLARONGA MARÍA MARCELA BARRIO 2023Oncology Research2023,31,2:0
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