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| 1 | Endoscopic ultrasound elastography for evaluation of lymph nodes and pancreatic masses:A multicenter study显示文摘AIM:To evaluate the ability of endoscopic ultrasound(EUS) elastography to distinguish benign from malignant pancreatic masses and lymph nodes.METHODS:A multicenter study was conducted and included 222 patients who underwent EUS examination with assessment of a pancreatic mass(n=121) or lymph node(n=101).The classification as benign or malignant,based on the real time elastography pattern,was compared with the classif ication based on the B-mode EUS images and with the fi nal diagnosis obtained by EUS-guided fi ne needle aspiration(EUS-FNA) and/or by surgical pathology.An interobserver study was performed.RESULTS:The sensitivity and specificity of EUS elastography to differentiate benign from malignant pancreatic lesions are 92.3% and 80.0%,respectively,compared to 92.3% and 68.9%,respectively,for the conventional B-mode images.The sensitivity and specificity of EUS elastography to differentiate benign from malignant lymph nodes was 91.8% and 82.5%,respectively,compared to 78.6% and 50.0%,respectively,for the B-mode images.The kappa coefficient was 0.785 for the pancreatic masses and 0.657 for the lymph nodes.CONCLUSION:EUS elastography is superior compared to conventional B-mode imaging and appears to be able to distinguish benign from malignant pancreatic masses and lymph nodes with a high sensitivity,specificity and accuracy.It might be reserved as a second line examination to help characterise pancreatic masses after negative EUS-FNA and might increase the yield of EUS-FNA for lymph nodes. | Marc Giovannini Botelberge Thomas Bories Erwan Pesenti Christian Caillol Fabrice Esterni Benjamin Monges Geneviève Arcidiacono Paolo Deprez Pierre Yeung Robert Schimdt Walter Schrader Hanz Szymanski Carl Dietrich Christoph Eisendrath Pierre Van Laethem Jean-Luc Devière Jacques Vilmann Peter Saftoiu Andrian | 2009 | World Journal of Gastroenterology2009，15，13： | 48 |
| 2 | 农业信息技术与精确农业的发展显示文摘介绍了美国精确农业发展现状及当前进行的主要工作 ,阐述精确农业就是信息农业的概念。着重介绍 SS-CM(根据田间具体情况作物管理系统 )系统和 Yield Map产量图在精确农业发展中的作用及 GIS与精确农业的不可分关系。 | 彭望禄 Pierre Robert 程惠贤 | 2001 | 农业工程学报2001，17，2： | 36 |
| 3 | The Clavien-Dindo Classification of Surgical Complications: Five-Year Experience显示文摘 | Pierre A. Clavien Jeffrey Barkun Michelle L. de Oliveira Jean Nicolas Vauthey Daniel Dindo Richard D. Schulick Eduardo de Santiba?es Juan Pekolj Ksenija Slankamenac Claudio Bassi Rolf Graf René Vonlanthen Robert Padbury John L. Cameron Masatoshi Makuuchi | 2009 | Annals of Surgery2009，，2： | 4 |
| 4 | ACC/AHA guidelines for the management of patients with unstable angina and non–st-segment elevation myocardial infarction显示文摘 | Eugene Braunwald Elliott M Antman John W Beasley Robert M Califf Melvin D Cheitlin Judith S Hochman Robert H Jones Dean Kereiakes Joel Kupersmith Thomas N Levin Carl J Pepine John W Schaeffer Earl E Smith David E Steward Pierre Theroux Raymond J Gibbons J | 2000 | Journal of the American College of Cardiology2000，，3： | 4 |
| 5 | Epididymis-specific lipocalin promoters显示文摘我们的目标是译解序列它 DNA 为附睾基因的 tissue-specificexpression 被要求。至少 6 epididymis 特定的 lipocalin 基因被知道。这些不同地在附睾被调整并且区域化。Lipocalin 5 (Lcn5 或 mE-RABP ) andLipocalin (Lcn8 或 mEP17 ) 8 是属于 epididymis 特定的 lipocalin 基因簇的相应基因。两个都, Lcn5 基因和 5.3 kb 倡导者的 5 kb 倡导者碎片直接 theLcn8 基因罐头碎裂在附睾(到远侧的头的 Lcn5 和到起始的片断的 Lcn8 ) 的 transgene 表示,显示这些倡导者碎片为 epididymis 特定的基因表示包含重要 cis-regulatoryelement。为了定义,推进调整基因表示的碎片, Lcn5 倡导者在转基因的鼠标被检查并且使附睾房间线不朽。在连续删除以后, Lcn5 基因的 1.8 kb 倡导者碎片是在转基因的老鼠的足够的 fortissue 特定、区域特定的基因表示。短暂 transfectionanalysis 表明抄写因素叉头框 A2 ( Foxa2 )与雄激素受体交往并且绑在 Lcn5 倡导者 activity.Immunohistochemistry 感应的雄激素依赖者显示了的 kb 和 1.3 kb 和 thatFoxa2 表示禁止的在 1.2 之间的 Lcn5 倡导者的 100 bp 碎片在附睾的 Foxa2 的一个限制表达式在哪儿 endogenousLcn5 基因表示被压制并且 Lcn5 倡导者的 Foxa2 抑制与在语料库和尾的 Lcn5 的表示的缺乏一致。我们的途径为附睾 lipocalin 基因规定的进一步的分析和 epididymalfunction 的灵活控制提供基本策略。 | Kichiya Suzuki Xiuping Yu Pierre Chaurand Yoshihiko Araki Jean-Jacques Lareyre Richard M. Caprioli Marie-Claire Orgebin-Crist Robert J. Matusik | 2007 | Asian Journal of Andrology2007，9，4： | 3 |
| 6 | Twist, a Master Regulator of Morphogenesis, Plays an Essential Role in Tumor Metastasis显示文摘 | Jing Yang Sendurai A Mani Joana Liu Donaher Sridhar Ramaswamy Raphael A Itzykson Christophe Come Pierre Savagner Inna Gitelman Andrea Richardson Robert A Weinberg | 2004 | Cell2004，，7： | 3 |
| 7 | Health-related quality of life, work productivity, and health care resource utilization of subjects with irritable bowel syndrome: Baseline results from logic (longitudinal outcomes study of gastrointestinal symptoms in Canada), a naturalistic study显示文摘 | Pierre Paré James Gray Sy Lam Robert Balshaw Shideh Khorasheh Martin Barbeau Suzanne Kelly Christopher R. McBurney | 2006 | Clinical Therapeutics2006，，10： | 2 |
| 8 | 2012 ACCF/AHA Focused Update Incorporated Into the ACCF/AHA 2007 Guidelines for the Management of Patients With Unstable Angina/Non–ST-Elevation Myocardial Infarction显示文摘 | Jeffrey L. Anderson Cynthia D. Adams Elliott M. Antman Charles R. Bridges Robert M. Califf Donald E. Casey William E. Chavey Francis M. Fesmire Judith S. Hochman Thomas N. Levin A. Michael Lincoff Eric D. Peterson Pierre Theroux Nanette K. Wenger R. Scott | 2013 | Journal of the American College of Cardiology2013，，23： | 2 |
| 9 | Efficacy of azacitidine compared with that of conventional care regimens in the treatment of higher-risk myelodysplastic syndromes: a randomised, open-label, phase III study显示文摘 | Pierre Fenaux Ghulam J Mufti Eva Hellstrom-Lindberg Valeria Santini Carlo Finelli Aristoteles Giagounidis Robert Schoch Norbert Gattermann Guillermo Sanz Alan List Steven D Gore John F Seymour John M Bennett John Byrd Jay Backstrom Linda Zimmerman David M | 2009 | Lancet Oncology2009，，： | 2 |
| 10 | Degradation Mechanisms of Vertical Cavity Surface Emitting Lasers, Quantum Electronics显示文摘 | Michael C Y Robert W H Pierre M P | 1996 | IEEE Journal1996，32，： | 2 |
| 11 | 农业信息技术与精确农业的发展显示文摘介绍了美国精确农业发展现状及当前进行的主要工作,阐述精确农业就是信息农业的概念。着重介绍SSCM(根据田间具体情况作物管理系统)系统和YieldMap产量图在精确农业发展中的作用及GIS与精确农业的不可分关系。 | 彭望禄 Pierre Robert 程惠贤 | 2001 | 中国农业信息快讯2001，，8： | 2 |
| 12 | Estimates of optimal vitamin D status显示文摘 | Bess Dawson-Hughes Robert P. Heaney Michael F. Holick Paul Lips Pierre J. Meunier Reinhold Vieth | 2005 | Osteoporosis International2005，，7： | 2 |
| 13 | Baossi–Warack monogenetic volcanoes, Adamawa Plateau,Cameroon: petrography, mineralogy and geochemistry显示文摘Three monogenetic cones in the Baossi–Warack area, Ngaoundéré, Adamawa Plateau forming part of the Cameroon Volcanic Line(CVL) are documented in this study. Basaltic lavas(<1 km^3) scattered around these vents and restricted volcaniclastic deposits were emplaced by Hawaiian and mild strombolian style eruptions. The lavas are porphyritic, mainly composed of olivine(chrysolite) and clinopyroxene(diopside and augite) phenocrysts and plagioclase(andesine) microphenocrysts. Accessory minerals include titano-magnetite and titano-hematite, nepheline,apatite and amphibole xenocrysts. Sanidine occurs in some samples and sodi-potassic albite in others. Some olivines and clinopyroxenes exhibit resorbed margins and thin reaction rims while plagioclase displays oscillatory zoning, and sieved textures as a result of magma mixing. Whole-rock geochemistry data indicates that the lavas are silica-undersaturated, composed of basanites and basalts, showing little compositional variations(SiO_2: 39.20 wt.%–48.01 wt.%,MgO: 5.29 wt.%–9.70 wt.%). Trace elements patterns of these lavas suggest they are enriched in LILE including Pb,probably due to crustal contamination. REE patterns suggest cogenetic magmas below Baossi 1 and Baossi 2 volcanoes,and distinct sources below Warack volcano and nearby lavas.The lavas studied show affinity to high-μ(HIMU), enriched type Ⅰ(EM1) and Oceanic Island Basalt(OIB)-like mantle signatures and thus indicate a heterogeneous mantle source underneath the vents as noted at other monogenetic and polygenetic volcanoes along the CVL. Primary melts derived from low degrees of partial melting(0.5%–2%) and encountered low rates of fractionation, and crustal contamination coupled with magma mixing. These melts evolved independently through structural weaknesses in the basement. | Anicet Feudjio Tiabou Robert Temdjim Pierre Wandji Jacques-Marie Bardintzeff Vivian Bih Che Edith Ekatah Bate Tibang Caroline Neh Ngwa Fran?ois Xavier Onana Mebara | 2019 | Acta Geochimica2019，38，1： | 2 |
| 14 | Twist, a Master Regulator of Morphogenesis, Plays an Essential Role in Tumor Metastasis显示文摘 | Jing Yang Sendurai A Mani Joana Liu Donaher Sridhar Ramaswamy Raphael A Itzykson Christophe Come Pierre Savagner Inna Gitelman Andrea Richardson Robert A Weinberg | 2004 | Cell2004，，7： | 1 |
| 15 | Biomechanical and morphological corneal response to placement of intrastromal corneal ring segments for keratoconus显示文摘 | Caroline Dauwe David Touboul Cynthia J. Roberts Ashraf M. Mahmoud Julien Kérautret Pierre Fournier Fran?ois Malecaze Joseph Colin | 2009 | Journal of Cataract & Refractive Surgery2009，，10： | 1 |
| 16 | The Network Architecture of the Connection Machine CM-5显示文摘 | Charles E. Leiserson Zahi S. Abuhamdeh David C. Douglas Carl R. Feynman Mahesh N. Ganmukhi Jeffrey V. Hill W.Daniel Hillis Bradley C. Kuszmaul Margaret A. St. Pierre David S. Wells Monica C. Wong-Chan Shaw-Wen Yang Robert Zak | 1996 | Journal of Parallel and Distributed Computing1996，，2： | 1 |
| 17 | Systemic Delivery of Bone Marrow–Derived Mesenchymal Stem Cells to the Infarcted Myocardium: Feasibility, Cell Migration, and Body Distribution显示文摘 | Israel M. Barbash Pierre Chouraqui Jack Baron Micha S. Feinberg Sharon Etzion Ariel Tessone Liron Miller Esther Guetta Dov Zipori Laurence H. Kedes Robert A. Kloner Jonathan Leor | 2003 | Circulation: Journal of the American Heart Association2003，，7： | 1 |
| 18 | Structure, chromosomal localization, and expression of 12 genes of the MAGE family显示文摘 | Etienne Plaen Catia Traversari José J. Gaforio Jean-Pierre Szikora Charles Smet Francis Brasseur Pierre Bruggen Bernard Lethé Christophe Lurquin Patrick Chomez Olivier Backer Thierry Boon Karen Arden Webster Cavenee Robert Brasseur | 1994 | Immunogenetics1994，，5： | 1 |
| 19 | Ginkgo biloba extract (EGb761) protects Na^+,K^+-ATPase isoenzymes during cerebral ischemia显示文摘 | PIERR S JAMME I ROBERT K | 2002 | Cell Mol Biol (Noisy-le-grand)2002，48，6： | 1 |
| 20 | Identifying important factors influencing corn yield and grain quality variability using artificial neural networks显示文摘 | Yuxin Miao David J. Mulla Pierre C. Robert | 2006 | Precision Agriculture2006，，2： | 1 |
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