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| 1 | Isolation of highly purity cellulose from wheat straw using a modified aqueous biphasic system显示文摘有从 8.39 慨楳? | Lifeng YAN Yi ZHAO Qing GU Wan LI | 2012 | Frontiers of Chemical Science and Engineering2012，6，3： | 3 |
| 2 | Experimental and numerical study on instability structure of the supersonic mixing layer(M_c = 0.5)显示文摘The parameters of instability wave of supersonic mixing layer(Mc=0.5,M1=3.5/M2=1.4) are measured by flow visualization and calculated by means of two-dimensional direct numerical simulaitons of the compressible Navier-Stokes equations.In both cases of the mixing layer with harmonic disturbance or not,the comparative results indicate that the wavelength of the two-dimensional wave is equal to the vortex spacing in the streamwise direction because the difference between them is less than 1%.However,the measured convective velocity of the large-scale structure deviates from the theoretical isentropic prediction about 10%.Here the measured value confirms that Mc,2 | YANG WuBing ZHUANG FengGan SHEN Qing GUAN FaMing WANG Qiang YI ShiHe ZHAO YuXin HE Lin TIAN LiFeng | 2009 | Science China(Physics,Mechanics & Astronomy)2009，52，10： | 2 |
| 3 | Cell-Based Biosensors Based on Light-Addressable Potentiometric Sensors for Single Cell Monitoring显示文摘 | Xu Gaixia Ye Xuesong Qing Lifeng Xu Ying Li Yah Li Rong Wang Ping | 2005 | Biosensors and Bioelectronics2005，20，： | 1 |
| 4 | Hydrodynamic Characteristics in an External Loop Airlift Slurry Reactor显示文摘Three different types of gas distributors were used in an external loop airlift slurry reactor to investigate the hydrodynamic characteristics. To predict the important hydrodynamic parameters, such as the total gas holdup, the slurry circulating velocity, the bubble size distribution, and the slip velocity between the gas phase and the slurry phase, the correlations are developed. The calculated results fit the experimental data very well. According to the influence of the solid holdup on the bubble size, the fluid flow in the reactor can be divided into two regimes, while a 10% value is regarded as the critical solid holdup value. When εs is≤10%, the bubble size is determined by both the gas phase and the slurry phase. When εs is ≥10%, the bubble size is determined mainly by the slurry phase. By analyzing the relationship between the slip velocity and the gas holdup, the bubble coalescence plays a key role in the slurry reactor. | Bian Qing Tang Xiaojin Hu Lifeng Wang Shaobing Zhang Zhanzhu | 2016 | China Petroleum Processing & Petrochemical Technology2016，18，3： | 1 |
| 5 | Cloning of human XAF1 gene promoter and assay of its transcription activity in a variety of cell lines显示文摘To investigate the regulation of tumor sup-pressor XAF1 gene expression in digestive system cancers,we studied XAF1 gene promoter transcription activity and mRNA level in digestive system cancer cell lines(human hepatoma cell line HepG2,human colon cancer cell line LoVo,and human gastric cancer cell line AGS)and nontumor cell lines(human embryonic liver cell line L02(L02 cells)and human embryonic kidney 293 cells[HEK293 cells])as controls.1395-bp-promoter fragment of XAF1 gene was amplified by polymerase chain reaction(PCR)and cloned into pGL3-basic vector and pEGFP-1 vector to assay its promoter transcription activity.The plasmids were transfected into a variety of cell lines by lipofectamine 2000.The promoter transcription activity was determined by dual-luciferase report assay,and enhanced greenfluorescent protein(EGFP)-positive cells were detected byfluorescence microscope.The expression of XAF1 mRNA in HEK293 and L02 were significantly higher than that in any of the three digestive system cancer cell lines.The dual-luciferase reporter assay showed that the promoter transcription activity in digestive system tumor cell lines transfected with pGL3-XAF1p promoter was apparently lower than that of both HEK293 and L02 cells.Expression of greenfluorescent protein(GFP)under the control of XAF1 promoter in the three digestive system cancer cell lines was lower than that of both HEK293 and L02 cells.The activities of pGL3-XAF1p in the three digestive system cancer cell lines after treatment with heat stress were significantly lower than those in the unstressed cells.The results suggested that remarkably down-regulated XAF1 mRNA expression in digestive system cancer cell lines may be due to loss of transcription activity of XAF1 promoter. | Qiong CHEN Qing YU Yuhu SONG Peiyuan Li Ying CHANG Zhijun WANG Lifeng LIU Wei WU Jusheng LIN | 2009 | Frontiers of Medicine2009，3，2： | 0 |
| 6 | Local administration of liposomal-based Plekhf1 gene therapy attenuates pulmonary fibrosis by modulating macrophage polarization显示文摘Idiopathic pulmonary fibrosis(IPF)is a fatal interstitial lung disease with limited therapeutic options.Macrophages,particularly alternatively activated macrophages(M2),have been recognized to contribute to the pathogenesis of pulmonary fibrosis.Therefore,targeting macrophages might be a viable therapeutic strategy for IPF.Herein,we report a potential nanomedicinebased gene therapy for IPF by modulating macrophage M2 activation.In this study,we illustrated that the levels of pleckstrin homology and FYVE domain containing 1(Plekhf1)were increased in the lungs originating from IPF patients and PF mice.Further functionality studies identified the pivotal role of Plekhf1 in macrophage M2 activation.Mechanistically,Plekhf1 was upregulated by IL-4/IL-13 stimulation,after which Plekhf1 enhanced PI3K/Akt signaling to promote the macrophage M2 program and exacerbate pulmonary fibrosis.Therefore,intratracheal administration of Plekhf1 siRNA-loaded liposomes could effectively suppress the expression of Plekhf1 in the lungs and notably protect mice against BLM-induced lung injury and fibrosis,concomitant with a significant reduction in M2 macrophage accumulation in the lungs.In conclusion,Plekhf1 may play a crucial role in the pathogenesis of pulmonary fibrosis,and Plekhf1 siRNA-loaded liposomes might be a promising therapeutic approach against pulmonary fibrosis. | Lifeng Yan Chenchen Hou Juan Liu Yi Wang Chenxi Zeng Jun Yu Tianyu Zhou Qing Zhou Shengzhong Duan Weining Xiong | 2023 | Science China(Life Sciences)2023，66，11： | 0 |
| 7 | Direct transformation of n-alkane into all-trans conjugated polyene via cascade dehydrogenation显示文摘Selective C(sp^(3))-H activation is of fundamental importance in processing alkane feedstocks to produce high-value-added chemical products.By virtue of an on-surface synthesis strategy,we report selective cascade dehydrogenation of n-alkane molecules under surface constraints,which yields monodispersed all-trans conjugated polyenes with unprecedented length controllability.We are also able to demonstrate the generality of this concept for alkyl-substituted molecules with programmable lengths and diverse functionalities,and more importantly its promising potential in molecular wiring. | Xuechao Li Kaifeng Niu Junjie Zhang Xiaojuan Yu Haiming Zhang Yuemin Wang Qing Guo Pengdong Wang Fangsen Li Zhengming Hao Chaojie Xu Yanning Tang Zhichao Xu Shuai Lu Peng Liu Guigu Xue Yen Wei Lifeng Chi | 2021 | National Science Review2021，8，10： | 0 |
| 8 | Synthesis, crystal structure and thermal analysis of a new stilbazolium salt crystal显示文摘 | Bing TENG Weijin KONG Ke FENG Fei YOU Lifeng CAO Degao ZHONG Lun HAO Qing SUN Sander van SMAALEN Wenhui GONG | 2015 | Frontiers of Materials Science2015，9，2： | 0 |
| 9 | Hole-Transporting Low-Dimensional Perovskite for EnhancingPhotovoltaic Performance显示文摘Halide perovskites with low-dimensionalities(2D or quasi-2D)have demonstrated outstanding stabilities compared to their 3D counterparts.Nevertheless,poor charge-transporting abilities of organic components in 2D perovskites lead to relatively low power conversion efficiency(PCE)and thus limit their applications in photovoltaics.Here,we report a novel hole-transporting low-dimensional(HT2D)perovskite,which can form a hole-transporting channel on the top surface of 3D perovskite due to self-assembly effects of metal halide frameworks.This HT2D perovskite can significantly reduce interface trap densities and enhance hole-extracting abilities of a heterojunction region between the 3D perovskite and hole-transporting layer.Furthermore,the posttreatment by HT2D can also reduce the crystal defects of perovskite and improve film morphology.As a result,perovskite solar cells(PSCs)can effectively suppress nonradiative recombination,leading to an increasement on photovoltage to>1.20 V and thus achieving>20%power conversion efficiency and>500 h continuous illumination stability.This work provides a pathway to overcome charge-transporting limitations in low-dimensional perovskites and delivers significant enhancements on performance of PSCs. | Fangfang Wang Qing Chang Yikai Yun Sizhou Liu You Liu Jungan Wang Yinyu Fang Zhengchun Cheng Shanglei Feng Lifeng Yang Yingguo Yang Wei Huang Tianshi Qin | 2021 | Research2021，，1： | 0 |
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