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| 1 | A Chromosome-Level Genome Assembly of Garlic (Allium sativum) Provides Insights into Genome Evolution and Allicin Biosynthesis显示文摘Garlic,an economically important vegetable,spice,and medicinal crop,produces highly enlarged bulbs and unique organosulfur compounds.Here,we report a chromosome-level genome assembly for garlic,with a total size of approximately 16.24 Gb,as well as the annotation of 57561 predicted protein-coding genes,making garlic the first Allium species with a sequenced genome.Analysis of this garlic genome assembly reveals a recent burst of transposable elements,explaining the substantial expansion of the garlic genome.We examined the evolution of certain genes associated with the biosynthesis of allicin and inulin neoseries-type fructans,and provided new insights into the biosynthesis of these two compounds.Furthermore,a large-scale transcriptome was produced to characterize the expression patterns of garlic genes in different tissues and at various growth stages of enlarged bulbs.The reference genome and large-scale transcriptome data generated in this study provide valuable new resources for research on garlic biology and breeding. | Xiudong Sun Siyuan Zhu Ningyang Li Yi Cheng Jing Zhao Xuguang Qiao Li Lu Shiqi Liu Yanzhou Wang Chan Liu Benping Li Wu Guo Shuang Gao Zemao Yang Fu Li Zheng Zeng Qing Tang Yupeng Pan Mengjiao Guan Jian Zhao Xiaomi ng Lu Huanwe n Meng Zhenlin Han Chun she ng Gao Wenkai Jiang Xing Zhao Shilin Tian Jianguang Su Zhihui Cheng Touming Liu | 2020 | Molecular Plant2020，13，9： | 14 |
| 2 | First experimental constraints on WIMP couplings in the effective field theory framework from CDEX显示文摘We present weakly interacting massive particles(WIMPs) search results performed using two approaches of effective field theory from the China Dark Matter Experiment(CDEX), based on the data from both CDEX-1B and CDEX-10 stages. In the nonrelativistic effective field theory approach, both time-integrated and annual modulation analyses were used to set new limits for the coupling of WIMP-nucleon effective operators at 90% confidence level(C.L.) and improve over the current bounds in the low mχregion. In the chiral effective field theory approach, data from CDEX-10 were used to set an upper limit on WIMP-pion coupling at 90% C.L. We for the first time extended the limit to the m_(χ)<6 GeV/c^(2) region. | Yi Wang Zhi Zeng Qian Yue LiTao Yang KeJun Kang YuanJing Li Mehment Agartioglu HaiPeng An JianPing Chang JingHan Chen YunHua Chen JianPing Cheng Cheng Yi Chiang WenHan Dai Zhi Deng ChangHao Fang XinPing Geng Hui Gong QiuJu Guo XuYuan Guo HongJian He Li He ShengMing He JinWei Hu TuChen Huang HanXiong Huang HaiTao Jia LiPing Jia Xi Jiang HauBin Li JianMin Li Jin Li MingXuan Li RenMingJie Li Xia Li YuLan Li Bin Liao FongKay Lin ShinTed Lin ShuKui Liu YanDong Liu Yu Liu YuanYuan Liu ZhongZhi Liu Hao Ma YuCai Mao QiYuan Nie JinHua Ning Hui Pan NingChun Qi Jie Ren XiChao Ruan ChangSong Shang Vivek Sharma Ze She Lakhwinder Singh Monoj Kumar Singh TianXi Sun ChangJian Tang WeiYou Tang Yang Tian GuangFu Wang Li Wang Qing Wang Yu Chen Wang YunXiang Wang Zhen Wang Henry Tsz-King Wong ShiYong Wu YuCheng Wu HaoYang Xing Yin Xu Tao Xue YuLu Yan Nan Yi ChunXu Yu HaiJun Yu JianFeng Yue Ming Zeng BingTao Zhang Lei Zhang FengShou Zhang ZhenYu Zhang KangKang Zhao MingGang Zhao JiFang Zhou ZuYing Zhou JingJun Zhu | 2021 | Science China(Physics,Mechanics & Astronomy)2021，64，8： | 3 |
| 3 | An Encapsulation of the Rare Earth Complex in Modified Mesoporous Molecular Sieve MCM-41显示文摘The encapsulation of a rare earth (RE) complex Eu(DBM)3phen in modified Si- MCM41 with 3 -aminopropyltriethoxy st.lane is reported for the first time. The luminescence intensity of the RE complex in the modified Si-MCM-41 is about 9 times as strong as in unmodified Si- MCM41 and the luminescence of the RE complex in the modified Si-MCM-41 has good color purity. | Qing Hong XU Lian She FU Lian Sheng LI Hong Jie ZHANG Qing Quo MENG Ru Ren XU Key Laboratory of Inorganic Synthesis & Preparative Chemistry, Department of Chemistry, Jilin University, Changchun 130023 Key Laboratory of Rare Earth Chemistry & Physic | 2000 | Chinese Chemical Letters2000，11，9： | 1 |
| 4 | Low-cost and Large-scale Fabrication Method for An Environmental- ly-friendly Super-hydrophobic Coating on Magnesium Alloy 显示文摘 | WANG Zhong-wei LI Qing SHE Zu-xin | 2012 | Journal of Materials Chemistry2012，22，： | 1 |
| 5 | The BAD protein integrates survival signling by EGFR/MAPK and PI3K/Akt kinase pathways in PTEN-deficient tumor cells显示文摘 | Qing-Bai She David B Solit Qing Ye | 2005 | Cancer Cell2005，8，： | 1 |
| 6 | AKT and cancer - is it all mTOR 显示文摘 | Rosen N She Qing - Bai | 2006 | Cancer Ce112006，10，4： | 1 |
| 7 | The BAD protein integrates survival signaling by EGFR/MAPKand PI3K/Akt kinase pathways in PTEN-deficient tumor cells 显示文摘 | Qing-Bai She David B Solit Qing Ye | 2005 | Cancer Cell2005，8，10： | 1 |
| 8 | 4E-BPI is a key effector of the oncogenic activation or the AKT and EHK sig?naling pathways that integrates their function in tumors显示文摘 | She Qing-Bai Halilovic E Ye Qing | 2010 | Cancer Cell2010，18，： | 1 |
| 9 | Knockdown of PU.1 AS lncRNA inhibits adipogenesis through enhancing PU.1 mRNA translation显示文摘 | Wei‐Jun Pang Li‐Gen Lin Yan Xiong Ning Wei Yu Wang Qing‐Wu Shen Gong‐She Yang | 2013 | J Cell Biochem2013，，11： | 1 |
| 10 | In-Situ Synthesis of Terbium Complex with Salicylic Acid in Silica Matrix by a Two-Step Sol-Gel Process显示文摘A process for in situ synthesis of terbium complex with salicylic acid by a two-step solgel method in silica matrix has been proposed. The luminescence properties of the silica gelscodoped with terbium and salicylic acid have also been discussed with respect to that of the geldoped with terbium and that of pure terbium complex with salicylic acid. | Lian She FU Hong Jie ZHANGl Shu Bin WANG Qing Guo MENG Km Yue YANG Jia Zuan NI(Laboratory of Rare Earth Chemistry and Physics, Changchun institute of Applied Chemistry,Chinese Academy of Sciences, Changchun, 130022) | 1998 | Chinese Chemical Letters1998，9，12： | 1 |
| 11 | Facile and fast fabrication of superhydrophobic surface on magnesium alloy显示文摘 | Zhongwei Wang Qing Li Zuxin She Funan Chen Longqin Li Xiaoxu Zhang Peng Zhang | 2013 | Applied Surface Science2013，，： | 1 |
| 12 | Researching the fabrication of anticorrosion superhydrophobic surface on magnesium alloy and its mechanical stability and durability显示文摘 | Zuxin She Qing Li Zhongwei Wang Longqin Li Funan Chen Juncen Zhou | 2013 | Chemical Engineering Journal2013，，： | 1 |
| 13 | FORMATION OF 16.24-DEHYDROBILADIENE-ab FROH PYRROMETHENONE显示文摘In the reaction of Pyrromethenone with bromine in methanol a newcompound with two azafulvenes.16.24-dehydrobiladiene-ab.was firstinvestigated. | Jin She MA~- Chang Qi WANG~1 Qing Qi CHEN~2 Yong Yong LIU Jing Zun WANG~1 Sheng JIN~11.Institute of Photographic Chemistry,Academia Sinica,Beijing 1001012.Department of Chemistry.Peking University.Beijing 1008713.Beijing Institute of Microchemistry.Beijing 100091 | 1993 | Chinese Chemical Letters1993，4，12： | 0 |
| 14 | A Novel Anonymous Authentication Scheme Based on Edge Computing in Internet of Vehicles显示文摘The vehicular cloud computing is an emerging technology that changes vehicle communication and underlying trafc management applications.However,cloud computing has disadvantages such as high delay,low privacy and high communication cost,which can not meet the needs of realtime interactive information of Internet of vehicles.Ensuring security and privacy in Internet of Vehicles is also regarded as one of its most important challenges.Therefore,in order to ensure the user information security and improve the real-time of vehicle information interaction,this paper proposes an anonymous authentication scheme based on edge computing.In this scheme,the concept of edge computing is introduced into the Internet of vehicles,which makes full use of the redundant computing power and storage capacity of idle edge equipment.The edge vehicle nodes are determined by simple algorithm of dening distance and resources,and the improved RSA encryption algorithm is used to encrypt the user information.The improved RSA algorithm encrypts the user information by reencrypting the encryption parameters.Compared with the traditional RSA algorithm,it can resist more attacks,so it is used to ensure the security of user information.It can not only protect the privacy of vehicles,but also avoid anonymous abuse.Simulation results show that the proposed scheme has lower computational complexity and communication overhead than the traditional anonymous scheme. | Xiaoliang Wang Xinhui She Liang Bai Yang Qing Frank Jiang | 2021 | Computers, Materials & Continua2021，，6： | 0 |
| 15 | Theoretical Studies on CH_3SiH_3+H→CH_3SiH_2+H_2 Reaction with the Variational Transitional State Theory显示文摘In this paper. the abstraction reaction of CH3SiH3 with H has been studied by using the 'direct dynamics' method of variational transition-state theory. which is based on the information on geometries. frequencies and energies calculalcd by ab inito along the minimum energy path. The rate constants of the title reaction were calculated for the range of temperature 298-1700 K. The rate constants calculated match well with the experimental values. | Qing Zhu ZHANG Chuan Pu LIU Shao Kun WANG Xin Ji XIE Miao ZHANG Yue She GU (School of Chemistry. State Key Laboratory of Crystal Materials, Shandong University Jinan 250100) | 2000 | Chinese Chemical Letters2000，11，2： | 0 |
| 16 | Expression and function of transcription factor RUNX2 in synovial tissues of rheumatoid arthritis显示文摘Objective:This study aimed to explore the expression profile of transcription factor Runt-related transcription factor 2(RUNX2)in the synovial tissues of rheumatoid arthritis(RA)and its effect on the apoptosis of RA fibroblast-like synovial cells(RA-FLS),and to screen new targets for the diagnosis,treatment and prognosis of RA.Methods:The expression and localization of mRNA and protein of RUNX2 in the synovial tissues were detected by real-time quantitative PCR(q PCR)and immunohistochemical staining,respectively.The effect of the expression of exogenous RUNX2 on the apoptosis process of RA-FLS cell line MH7A was investigated by flow cytometry,and the activation of NF-κB signaling pathway was detected by western blotting.Results:The expression of RUNX2 mRNA was significantly higher in the synovial tissues from RA patients,compared to that in the OA patients(P<0.05).RUNX2 protein was mainly localized in the nuclear of the RA synovial cells.Overexpression of exogenous RUNX2 could notably decrease the apoptosis of RA-FLS,which was substantially reversed by pretreatment with SN50,a specific inhibitor of NF-κB pathway.Compared with blank group and negative control group(p CMV6-AC-GFP-vector),the apoptotic rate of exogenous RUNX2 overexpressing(pCMV6-AC-GFP-RUNX2)MH7A cells was significantly decreased(P<0.05).NF-κB signaling pathway activity was significantly increased(P<0.05),and this effect could be effectively reversed by NF-κB signal pathway-specific inhibitor SN5.Conclusion:The high expression of UNX2 in RA synoviocytes could significantly inhibit the spontaneous apoptosis of cells,and it was related to the abnormal activation of NF-κB signaling pathway.In-depth studies of RUNX2/NF-κB signaling pathways will help to identify novel therapeutic targets for RA. | Jin Zhang Xinhu Wang Xiajun Liu Yuanchi Huang Qing She | 2017 | 广西医科大学学报2017，34，10： | 0 |
| 17 | Preparation and Characterization of Layered Compound Zirconium Bis(monohydrogenphosphate) Intercalated with Rare Earth Complex显示文摘Layered compound zirconium his(monohydrogenphosphate)(α-ZrP) intercalated with rare earth complex Eu(DBM)3phen was prepared. The pre-intercalation of p-methoxyaniline into α-ZrP makes the interlayer separation large enough to exchange PMA with europium complex, thus, the luminescent assembly was prepared. This was confirmed by X-ray diffraction, UV-visible spectra and elemental analysis. The fluorescence spectra and lifetime of the assembly were also presented. | Lian She FU1 Qing Hong XU2 Hong Jie ZHANG1 Lian Sheng LI2 Jia Zuan NI1 Ru Ren XU 2 (1Key Laboratory of Rare Earth Chemistry & Physics, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022 2 Key Laboratory of Inorga | 2000 | Chinese Chemical Letters2000，11，2： | 0 |
| 18 | Development and implementation of a dynamic and 4D GIS based on semantic location model显示文摘In the big data era,robust solutions are obliged to be proposed to integrate and represent data from different formats and with different contents to assist the decision-making.Current cartographic and geographic information systems have limited capabilities for solving these problems.This paper describes an automatic and comprehensive system that conducts data fusion from all potentially related sources.In this system,a new Semantic Location Model(SemLM)is established to present the semantic concepts and location feature and demonstrate how locations are interrelated.In the SemLM,various types of location descriptors in different application scenarios can be analyzed and understood.Additionally,considering the challenges involved in data-intensive computation and visualization,this paper implements a Place-based Pan-Information System(P2S)as an innovative 4D system that dynamically associates and visualizes place-based information,using public security as the case study. | Xinyan Zhu Tao Hu Xinyue Ye Wei Guo Liang Huang Hanjiang Xiong Haojun Ai Bing She Qing Xiong Lian Duan | 2019 | Geo-Spatial Information Science2019，22，3： | 0 |
| 19 | Cryo-induced closely bonded heterostructure for effective CO2 conversion:The case of ultrathin BP nanosheets/g-C3N4显示文摘Black phosphorus(BP),an interesting and multi-functional non-metal material,has attracted widespread attention.In this work,2D BP/2D g-C3N4 heterostructure had been fabricated at extremely low temperature,which was used to reduce CO2 for the first time.With introduction of 2D BP,the separation of photogenerated holes and electrons was extremely boosted,and composites showed excellent photocatalytic performance(CO2 to CO).Meanwhile,the targeted composite could keep high selectivity for CO generation and CO generation rate can be up to 187.7μmol g−1 h^−1.The formation process of the unique heterostructure and the key factor affecting the photocatalytic performance were also discussed.This work provides a new approach for designing metal free photocatalyst,which is used for CO2 reduction. | Guli Zhou Jinman Yang Xingwang Zhu Qidi Li Qing Yu Wiam El-alami Chongtai Wang Yuanbin She Junchao Qian Hui Xu Huaming Li | 2020 | Journal of Energy Chemistry2020，29，10： | 0 |
| 20 | DNA analysis of a pedigree with Myotonic Dystrophy in Songiang county Shanghai显示文摘Objective To make the molecular analysis of a pedigree with myotonic dystrophy (DM) in Songjiang county Shanghai China, and to observe the connection between CTG trinucleotide repeat number and clinical features in a pedigreee with DM. Beckground Previous reports of CTG repeat numbers in a pedigree with DM was less in China. The study showed normal and expanded CTG repeat numbers in a Chinese patients with DM. Methods CTG trinucleotide repeat numbers were analyzed by using Long Expand TM Template PCR system. Results Four of eight clinical patients had expanded DM allele, the other four had no expanded CTG copies. Seven of eight suspicious DM cases had expanded CTG repeat numbers and were therefore genetically diagnosed DM, and an asymptomatic individual was dianosed a doubted DM patient by DNA analysis. High risk of DM in six of seven individuals was ruled out, and a clinical doubted DM individual was ascertained a normal person by molecular analysis. A positive correlation was found between early onset and expanded CTG repeat number in six parent(or grandparent)/child pairs, but in the pair No Ⅱ2/NoⅣ7 CTG repeat numbers were reduced from 3100 in the grandmother to 175 in her grandson and there was no anticipation phenomenon. Discussion it is possible that these patients represent a form of allelic heterogeneity for DM. Conclusion The measurement of CTG repeat number can help to ascertain the diagnosis of DM. | Hui-Min Zheng Hui-jun Xie She Qing Zhang | 2000 | 中国临床神经科学2000，8，z1： | 0 |
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