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| 1 | Spatial concentration,congener profiles and inhalation risk assessment of PCDD/Fs and PCBs in the atmosphere of Tianjin,China显示文摘Polychlorinated dibenzo-p-dioxins/dibenzofurans(PCDD/Fs) and polychlorinated biphenyls(PCBs) were monitored in a seasonal passive sampling scheme during June 2008 and January 2009 to investigate the spatial concentration,congener profiles and evaluate the potential inhalation risk in different functional areas in Tianjin,China.The spatial air concentrations and I-TEQs ranged 1.08×102-8.19×10 3 fg m-3(average 2.63×103 fg m-3) and 4.08-325 fg I-TEQ m-3(average 91.4 fg I-TEQ m-3) respectively for PCDD/Fs.The concentration and I-TEQs of PCBs were 3.08×104-3.01×105 fg m-3(average 1.39×105 fg m-3) and 1.72-49.6 fg I-TEQ m-3(average 18.5 fg I-TEQ m-3).It is obvious that PCB concentrations were several hundred times higher than the PCDD/Fs.However,the ambient air PCDD/Fs contributed a major part to the total toxicity equivalents,varying from 72.7% to 89.0%(average 81.8%).The atmospheric PCDD/F levels were observed to be higher in winter for most of sampling sites in the downtown.Besides,inhalation risk assessment showed that local residents might suffer more risk near the point sources than those in living area,industrial zones and background area in Tianjin City.However,the total daily dioxin intake was approximately several to hundreds of times lower than the WHO criteria,showing relatively low exposure risks from the impact of industry point sources in Tianjin City. | DING Lei LI YingMing WANG Pu LI XiaoMin ZHAO ZongShan RUAN Ting ZHANG QingHua | 2013 | Chinese Science Bulletin2013，58，9： | 17 |
| 2 | Seasonal trend of ambient PCDD/Fs in Tianjin City, northern China using active sampling strategy显示文摘The spatial concentrations, seasonal trends, profiles and congener pairs of ambient polychlorinated dibenzo-p-dioxins (PCDDs) and polychlorinated dibenzofurans (PCDFs) were investigated within a seasonally active sampling scheme during Jun 2008 and Jan 2009 in Tianjin City, northern China. The PCDD/F concentrations ranged 14.2-172 fg I-TEQ/m3 (average 69.3 fg I-TEQ/m3 ) in summer and (89.8-1.01)×103 fg I-TEQ/m3 (average 509 fg I-TEQ/m3 ) in winter, respectively, except for the E-waste dismantling site where much higher values were observed (1.04×103 fg I-TEQ/m3 in summer and 7.123×103 fg I-TEQ/m3 in winter). The results indicated a significantly seasonal trend with higher TEQ values in winter as compared with summer, which could be related to increased emission sources and seasonal variations of the atmospheric boundary layer height. 2,3,4,7,8-PeCDF was the dominant contributor to the total PCDD/F toxic equivalents, and 2,3,7,8-TCDD was detected at almost all the sampling sites in winter. Most of the similarly substituted PCDD/F congener pairs exhibited high correlations, suggesting that they might have similar environmental fate or sources. But different seasonal and spatial distributions of PCDD/F concentrations indicated that the emission sources might be intermittent. | Lei Ding Yingming Li Pu Wang Xiaomin Li Zongshan Zhao Qinghua Zhang Ting Tuan Guibin Jiang | 2012 | Journal of Environmental Sciences2012，24，11： | 16 |
| 3 | Reversal of B-cell hyperactivation and functional impairment is associated with HBsAg seroconversion in chronic hepatitis B patients显示文摘B 房间对再感染在肝炎 B 病毒(HBV ) 和保护的清理起一个重要作用。然而,与长期的 HBV 感染的结果被联系的这些房间的功能的特征仍然保持未知。我们包括地在不同阶段从 CHB 病人调查了外部 B 房间子集的频率,显型,和功能:有免疫力的忍耐(信息技术) ,有免疫力的激活(IA ) ,有免疫力的清理(IC ) ,有 HBsAg seroconversion 的应答者(解决的病人, RP ) ,并且健康控制(HC ) 。IA 病人与另外的组相比显示了外部血记忆 B 房间的更低的百分比。B 房间的全面 polyclonal 激活,由激活标记和 IgG 和 IgM 的分泌物的高水平显示了,在 IA 病人被观察。这 B 房间 hyperactivation 能被增加的 IFN-α 导致;并且在 IA 病人的可溶的 CD40 ligands。尤其是,合作激发器分子 CD80 和浆液 HBsAb 的表示和 HBsAg 特定的 B 房间的频率显著地与 HC 题目相比在信息技术, IA,和 IC 病人被减少。更重要地, B 房间 hyperactivation, co-stimulatory 分子 downregulation 和 HBsAg 特定的 B 房间缺陷在 RP 病人被颠倒。B 房间 hyperactivation 和功能的缺陷的颠倒在长期的肝炎 B 病人与 HBsAg seroconversion 被联系。 | Xiangsheng Xu Qinghua Shang Xinyue Chen Weimin Nie Zhengsheng Zou Ang Huang Ming Meng Lei Jin Ruonan Xu Ji-Yuan Zhang Junliang Fu Lifeng Wang Zirong Tang Yunbo Xie Xiaoming Yang Zheng Zhang Fu-Sheng Wang | 2015 | Cellular & Molecular Immunology2015，12，3： | 15 |
| 4 | Research Progress on Heat Stress of Rice at Flowering Stage显示文摘Global warming has caused frequent occurrence of heat stress at the flowering stage of single-season rice in the Yangtze River region of China, which results in declines of spikelet fertility and yield in rice. Rice flowering stage is the most sensitive period to high temperatures, and therefore, the key for heat stress happening is the flowering stage coinciding with high temperature, which causes spikelet fertility decreasing in heat-sensitive varieties, and is the major factor for heat injury differences among various rice planting regions. With the development of rice breeding, temperature indexes for heat stress has been converted from daily maximum temperature of 35 oC to 38 oC with the stress duration of more than 3 d. During the flowering stage, anther dehiscence inhibition and low pollen shedding onto the stigma are two main reasons for spikelet fertility reduction under high temperatures. At panicle initiation stage, high temperatures aggravate spikelet degeneration, and destroy floral organ development. Various types of rice varieties coexist in production, and indica-japonica hybrid rice demonstrates the highest heat resistance in general, followed by indica and japonica rice varieties. In production, avoiding high temperature is the main strategy of preventing heat stress, and planting suitable cultivars and adjustment of sowing date are the most effective measures. Irrigation is an effective real-time cultivation measure to decline the canopy temperature during the rice flowering stage. We suggested that further study should be focused on exploring heat injury differences among different rice variety types, and innovating rice-planting methods according to planting system changes in rice planting regions with extreme heat stress. Meanwhile, high temperature monitor and warning systems should be improved to achieve optimal heat stress management efficiencies. | WANG Yaliang WANG Lei ZHOU Jianxia HU Shengbo CHEN Huizhe XIANG Jing ZHANG Yikai ZENG Yongjun SHI Qinghua ZHU Defeng ZHANG Yuping | 2019 | Rice science2019，26，1： | 13 |
| 5 | Microfossils and molecular records in oil shales of the Songliao Basin and implications for paleo-depositional environment显示文摘Several oil shale beds, over 10 m thick, occur at the base of the first member of the Upper Cretaceous Qingshankou Formation (K2qn1) in the Songliao Basin. They act both as excellent source rocks for conventional oil and as potential oil deposit for shale oil production. Here we combine micropaleon-tology with organic geochemistry to investigate the paleo-depositional environment and organic source characteristics of the oil shales and black shales. Our results indicate that algal remains are dominant microfossils in K2qn1 oil shales, and their relatively high abundance suggests a major algal thriving event during the oil shale deposition. The presence of fresh water and brackish water species, Sentusidinium, Vesperopsis and Nyktericysta, and marine or brackish water deltaic and lagoonal species such as Kiokansium and Dinogymniopsis demonstrate that this paleo-continental lake was influenced by marine transgressions at the time of K2qn1 oil shale formation. The extremely low pristine/phytane ratios, relatively high abundance of gammacerane and 4-methyl steranes, and low δ 13C values of C14-C37 n-alkanes in the oil shale organic extracts indicate the deposition of oil shales in anoxic and highly stratified water columns and the significant contribution of lacustrine algae to sedimentary organic matter. High molecular-weight paraffinic hydrocarbons with unusually high abundance of nC43, nC45, and nC47 may be related to special algal species associated with marine transgression events. The giant water body of Songliao paleo-lake and the change in the organic and chemical environment (such as nutrition source and water column salinity) associated with seawater transgression into the lake are among the most important reasons for oil shales in the Songliao Basin being different from mudstone and oil shale in other rifted basins. | FENG ZiHui FANG Wei WANG Xue HUANG ChunYan HUO QiuLi ZHANG JuHe HUANG QingHua ZHANG Lei | 2009 | Science China Earth Sciences2009，52，10： | 12 |
| 6 | Recent progress and perspective of electrochemical CO_(2) reduction towards C_(2)-C_(5) products over non-precious metal heterogeneous electrocatalysts显示文摘Electroreduction of carbon dioxide(CO_(2)ER)into value-added chemical compounds has presented as a promising route for renewable carbon cycle,which alleviates global warming concern.Compared with traditional C1 products,high-value multicarbon products converted from atmospheric CO_(2) via CO_(2)ER have attracted dramatic interest due to their significant economic efficiency,however desired catalytic selectivity of multicarbon products is difficult to achieve because of the high thermodynamic barriers and complex reaction pathways.To replace currently used precious-metal based catalysts,developing highly efficient and precious-metal-free CO_(2)ER catalysts based on earth abundant elements is the top priority to meet the requirements of industrialization.Although certain progress has been made,there are still few systematic reports on the non-precious metal heterogeneous(NPMH)CO_(2)ER electrocatalysts for efficient conversion of CO_(2) to multicarbon products.Herein,we summarize the latest research advances in recent developments of NPMH electrocatalysts,including nanostructured Cu,Cu-based bimetallic catalysts,Cu-based complexes,and carbon-based Cu-free catalysts for electroreduction of CO_(2) into high-value multicarbon products.The corresponding CO_(2)ER performances are discussed in the order of the types of multicarbon products,specifically for ethanol(C2H5OH),ethylene(C2H4),ethane(C2H6),acetic acid(CH3COOH),propanol(C3H7OH),and other O^(2+)products with a special attention paid to understand the structure-activity relationship.Moreover,key strategies and characterization techniques for catalytic mechanism insights,and unsolved issues and future trends for enhancing the CO_(2)ER performance of NPMH electrocatalysts are highlighted,which provides a constructive guidance on the development of CO_(2)ER electrocatalysts with high activity and selectivity for multicarbon products. | Jiayi Chen Tingting Wang Zhongjian Li Bin Yang Qinghua Zhang Lecheng Lei Pingyun Feng Yang Hou | 2021 | Nano Research2021，14，9： | 7 |
| 7 | Albedo of Coastal Landfast Sea Ice in Prydz Bay,Antarctica:Observations and Parameterization显示文摘The snow/sea-ice albedo was measured over coastal landfast sea ice in Prydz Bay, East Antarctica(off Zhongshan Station)during the austral spring and summer of 2010 and 2011. The variation of the observed albedo was a combination of a gradual seasonal transition from spring to summer and abrupt changes resulting from synoptic events, including snowfall, blowing snow, and overcast skies. The measured albedo ranged from 0.94 over thick fresh snow to 0.36 over melting sea ice. It was found that snow thickness was the most important factor influencing the albedo variation, while synoptic events and overcast skies could increase the albedo by about 0.18 and 0.06, respectively. The in-situ measured albedo and related physical parameters(e.g., snow thickness, ice thickness, surface temperature, and air temperature) were then used to evaluate four different snow/ice albedo parameterizations used in a variety of climate models. The parameterized albedos showed substantial discrepancies compared to the observed albedo, particularly during the summer melt period, even though more complex parameterizations yielded more realistic variations than simple ones. A modified parameterization was developed,which further considered synoptic events, cloud cover, and the local landfast sea-ice surface characteristics. The resulting parameterized albedo showed very good agreement with the observed albedo. | Qinghua YANG Jiping LIU Matti LEPPRANTA Qizhen SUN Rongbin LI Lin ZHANG Thomas JUNG Ruibo LEI Zhanhai ZHANG Ming LI Jiechen ZHAO Jingjing CHENG | 2016 | Advances in Atmospheric Sciences2016，33，5： | 7 |
| 8 | Regulatory mechanism of hormones of the pituitary-target gland axes in kidney-Yang deficiency based on a support vector machine model显示文摘OBJECTIVE:To study the development mechanism of kidney-Yang deficiency through the establishment of support vector machine models of relevant hormones of the pituitary-target gland axes in rats with kidney-Yang deficiency syndrome.METHODS:The kidney-Yang deficiency rat model was created by intramuscular injection of hydrocortisone,and contents of the hormones of the pituita- ry-thyroid axis:thyroid stimulating hormone(TSH),3,3',5-triiodothyronine(T_3) and thyroxine(T_4);hormones of the pituitary-adrenal gland axis:adrenocorticotropic hormone(ACTH) and Cortisol(CORT);and hormones of the pituitary-gonadal axis:luteinizing hormone(LH),follicle-stimulating hormone(FSH),and testosterone(T),were determined in the early,middle,and advanced stages.Ten support vector regression(SVR) models of the hormones were established to analyze the mutual relationships among the hormones of the three axes.RESULTS:The feedback control action of the pituitary-adrenal axis began to lose efficacy from the middle stage of kidney-Kong deficiency.The contents all hormones of the three pituitary-target gland axes decreased in the advanced stage.Relative errors of the jackknife test of the SVR models all were less than 10%.CONCLUSION:Imbalances in mutual regulation among the hormones of the pituitary-target gland axes,especially loss of effectiveness of the pituitary-adrenal axis,is one pathogenesis of kidney-Yang deficiency.The SVR model can accurately reflect the complicated non-linear relationships among pituitary-target gland axes in rats with of kidney-Yang deficiency. | Wang Xiufeng Zhang Lei Huang Rongbo Wu Qinghua Min Jianxin Ma Na Luo Laicheng | 2015 | Journal of Traditional Chinese Medicine2015，35，2： | 7 |
| 9 | Research on the Relationship between Molecular Activity of Additives and Lubricating Performance of Aluminum Rolling Oil显示文摘In this paper,an ab initio,local density functional(LDF)method was used to explore the relationship between the molecular properties of additives and the lubricating performance of aluminum rolling oil.The structural properties of butyl stearate,dodecanol,docosanol,and methyl dodecanoate were studied according to the density functional theory.The calculated data showed that the atoms in or around the functional groups might be likely the reacting sites.Because of the different functional groups and structure of ester and alcohol,two types of complex additives,dodecanol and butyl stearate,methyl dodecanoate and butyl stearate,respectively,were chosen for studying their tribological properties and performing aluminum cold rolling experiments.The test results agreed with the calculated results very well.The complex ester,viz.methyl dodecanoate and butyl stearate,had the best lubricating performance with a friction coefficient of 0.084 1 and a permissive-rolling thickness of 0.040 mm as compared with that of dodecanol-butyl stearate-base oil formulation. | Xia Lei Sun Jianlin Zeng Yingfeng Zhang Min Duan Qinghua | 2013 | China Petroleum Processing & Petrochemical Technology2013，15，3： | 6 |
| 10 | Review of research on Arctic sea ice physics based on the Chinese National Arctic Research Expedition显示文摘China launched its Arctic research program and organized the first Chinese National Arctic Research Expedition(CHINARE-Arctic) in 1999. By 2016, six further expeditions had been conducted using the R/V Xuelong. The main region of the expeditions has focused on the Pacific sector of the Arctic Ocean for sea ice observations. The expeditions have used icebreaker, helicopter, boat, floe, and buoy platforms to perform these observations. Some new technologies have been developed, in particular, the underway auto-observing system for sea ice thickness using an electromagnetic instrument. The long-term measurement systems, e.g., the sea ice mass balance buoy, allow observations to extend from summer to winter. Some international cooperation projects have been involved in CHINARE-Arctic, especially the 'Developing Arctic Modeling and Observing Capabilities for Long-Term Environmental Studies' project funded by the European Union during the International Polar Year. Arctic sea ice observations have been used to verify remote sensing products, identify changes in Arctic sea ice, optimize the parameterizations of sea ice physical processes, and assess the accessibility of ice-covered waters, especially around the Northeast Passage. Recommendations are provided as guidance to future CHINARE-Arctic projects. For example, a standardized operation system of sea ice observations should be contracted, and the observations of sea ice dynamics should be enhanced. The upcoming launch of a new Chinese icebreaker will allow increased ship time in support of future CHINARE Arctic oceanographic investigations. | LEI Ruibo ZHANG Zhanhai LI Zhijun YANG Qinghua LI Bingrui LI Tao | 2017 | Advances in Polar Science2017，28，2： | 5 |
| 11 | Integrated System of Solar Cells with Hierarchical NiCo2O4 Battery-Supercapacitor Hybrid Devices for Self-Driving Light-Emitting Diodes显示文摘An integrated system has been provided with a-Si/H solar cells as energy conversion device,NiCo2O4 battery-supercapacitor hybrid(BSH)as energy storage device,and light emitting diodes(LEDs)as energy utilization device.By designing three-dimensional hierarchical NiCo2O4 arrays as faradic electrode,with capacitive electrode of active carbon(AC),BSHs were assembled with energy density of 16.6 Wh kg-1,power density of 7285 W kg-1,long-term stability with 100% retention after 15,000 cycles,and rather low self-discharge.The NiCo2O4//AC BSH was charged to 1.6 V in 1 s by solar cells and acted as reliable sources for powering LEDs.The integrated system is rational for operation,having an overall efficiency of 8.1% with storage efficiency of 74.24%.The integrated system demonstrates a stable solar power conversion,outstanding energy storage behavior,and reliable light emitting.Our study offers a precious strategy to design a self-driven integrated system for highly efficient energy utilization. | Yuliang Yuan Yangdan Lu BeiEr Jia Haichao Tang Lingxiang Chen YuJia Zeng Yang Hou Qinghua Zhang Qinggang He Lei Jiao Jianxing Leng Zhizhen Ye Jianguo Lu | 2019 | Nano-Micro Letters2019，11，3： | 5 |
| 12 | Molecular architecture of the luminal ring of the Xenopus laevis nuclear pore complex显示文摘The nuclear pore complex(NPC)mediates the flow of substances between the nucleus and cytoplasm in eukaryotic cells.Here we report the cryo-electron tomography(cryo-ET)structure of the luminal ring(LR)of the NPC from Xenopus laevis oocyte.The observed key structural features of the LR are independently confirmed by single-particle cryo-electron microscopy(cryo-EM)analysis.The LR comprises eight butterfly-shaped subunits,each containing two symmetric wings.Each wing consists of four elongated,tubular protomers.Within the LR subunit,the eight protomers form a Finger domain,which directly contacts the fusion between the inner and outer nuclear membranes and a Grid domain,which serves as a rigid base for the Finger domain.Two neighboring LR subunits interact with each other through the lateral edges of their wings to constitute a Bumper domain,which displays two major conformations and appears to cushion neighboring NPCs.Our study reveals previously unknown features of the LR and potentially explains the elastic property of the NPC. | Yanqing Zhang Sai Li Chao Zeng Gaoxingyu Huang Xuechen Zhu Qifan Wang Kunpeng Wang Qiang Zhou Chuangye Yan Wusheng Zhang Guangwen Yang Minhao Liu Qinghua Tao Jianlin Lei Yigong Shi | 2020 | Cell Research2020，30，6： | 4 |
| 13 | A Superaerophobic Bimetallic Selenides Heterostructure for Efficient Industrial-Level Oxygen Evolution at Ultra-High Current Densities显示文摘Cost-effective and stable electrocatalysts with ultra-high current densities for electrochemical oxygen evolution reaction(OER)are critical to the energy crisis and environmental pollution.Herein,we report a superaerophobic three dimensional(3D)heterostructured nanowrinkles of bimetallic selenides consisting of crystalline NiSe2 and NiFe2Se4 grown on NiFe alloy(NiSe2/NiFe2Se4@NiFe)prepared by a thermal selenization procedure.In this unique 3D heterostructure,numerous nanowrinkles of NiSe2/NiFe2Se4 hybrid with a thickness of ~100 nm are grown on NiFe alloy in a uniform manner.Profiting by the large active surface area and high electronic conductivity,the superaerophobic NiSe2/NiFe2Se4@NiFe heterostructure exhibits excellent electrocatalytic activity and durability towards OER in alkaline media,outputting the low potentials of 1.53 and 1.54 V to achieve ultra-high current densities of 500 and 1000 mA cm^−2,respectively,which is among the most active Ni/Fe-based selenides,and even superior to the benchmark Ir/C catalyst.The in-situ derived FeOOH and NiOOH species from NiSe2/NiFe2Se4@NiFe are deemed to be efficient active sites for OER. | Jiaxin Yuan Xiaodi Cheng Hanqing Wang Chaojun Lei Sameer Pardiwala Bin Yang Zhongjian Li Qinghua Zhang Lecheng Lei Shaobin Wang Yang Hou | 2020 | Nano-Micro Letters2020，12，8： | 4 |
| 14 | Investigation of the thermodynamic processes of a floe-lead system in the central Arctic during later summer显示文摘Thermodynamic processes of a system involving a floe and a small lead in the central Arctic were investigated during the ice-camp period of the third Chinese National Arctic Research Expedition from 20 to 28 August,2008.The measurements included surface air temperatures above the floe,spectral albedo of the lead,seawater temperatures in the lead and under the ice cover,and the lateral and bottom mass balance of the floe.The surface air temperature at 1.15 m remained below 0℃throughout the observation period and sea ice had commenced its annual cycle of growth in response to autumn cooling during the study.The surface of the lead was frozen by 23 August,after which the spectral albedo of the thin-ice-covered lead in the band of 320 950 nm was 0.46 ±0.03,the seawater temperatures both in the lead and under the ice cover,as well as the vertical seawater-temperature gradient in the lead decreased gradually,and the oceanic heat under the ice was maintained at a low level approaching 0 W/m2.By the end of the measurement,the thickness of the investigated floe had reached its annual minimum,while the lateral of the floe was still in the melting phase,with a mean melting rate of 1.0 ±0.3 cm/d during the measurement,responding to an equivalent latent heat flux of 21 ±6 W/m2.The lateral melting of the floe had made a more significant contribution to the sea-ice mass balance than the surface and bottom melting in the end of August. | LEI RuiBo LI ZhiJun CHENG Bin YANG QingHua LI Na | 2011 | Chinese Journal of Polar Science2011，22，1： | 4 |
| 15 | Two-stage local constrained sparse coding for fine-grained visual categorization显示文摘Fine-grained visual categorization(FGVC)[1,2]classifies the objects into categories which are both visually and semantically similar.Currently,the FGVC has included many species,i.e.,flowers,birds,and dogs.In these species,all categories have a characteristic with intra-class diversity and inter-class similarity. | Lihua GUO Chenggang GUO Lei LI Qinghua HUANG Yanshan LI Xuelong LI | 2018 | Science China(Information Sciences)2018，61，1： | 4 |
| 16 | Bract suppression regulated by the miR156/529-SPLs-NL1-PLA1 module is required for the transition from vegetative to reproductive branching in rice显示文摘Reproductive transition of grasses is characterized by switching the pattern of lateral branches,featuring the suppression of outgrowth of the subtending leaves(bracts)and rapid formation of higher-order branches in the inflorescence(panicle).However,the molecular mechanisms underlying such changes remain largely unknown.Here,we show that bract suppression is required for the reproductive branching in rice.We identified a pathway involving the intrinsic time ruler microRNAI56/529,their targets SQUAMOSA PROMOTER BINDING PROTEIN LIKE(SPL)genes,NECK LEAF1(NL1),and PLASTOCHRON1(PLA1),which regulates the bract outgrowth and thus affects the pattern switch between vegetative and reproductive branching.Suppression of the bract results in global reprogramming of transcriptome and chromatin accessibility following the reproductive transition,while these processes are largely dysregu-lated in the mutants of these genes.These discoveries contribute to our understanding of the dynamic plant architecture and provide novel insights for improving crop yields. | Lei Wang Luchang Ming Keyan Liao Chunjiao Xia Shengyuan Sun Yu Chang Hongkai Wang Debao Fu Conghao Xu Zhengji Wang Xu Li Weibo Xie Yidan Ouyang Qinglu Zhang Xianghua Li Qinghua Zhang Jinghua Xiao Qifa Zhang | 2021 | Molecular Plant2021，14，7： | 2 |
| 17 | Structure of the cytoplasmic ring of the Xenopus laevis nuclear pore complex by cryo-electron microscopy single particle analysis显示文摘The nuclear pore complex(NPC)exhibits structural plasticity and has only been characterized at local resolutions of up to 15 A for the cytoplasmic ring(CR).Here we present a single-particle cryo-electron microscopy(cryo-EM)structure of the CR from Xenopus laevis NPC at average resolutions of 5.5-7.9A,with local resolutions reaching 4.5 A.Improved resolutions allow identification and placement of secondary structural elements in the majority of the CR components.The two Y complexes in each CR subunit interact with each other and associate with those from flanking subunits,forming a circular scaffold.Within each CR subunit,the Nup358-containing region wraps around the stems of both Y complexes,likely stabilizing the scaffold.Nup205 connects the short arms of the two Y complexes and associates with the stem of a neighboring Y complex.The Nup214-containing region uses an extended coiled-coil to link Nup85 of the two Y complexes and protrudes into the axial pore of the NPC.These previously uncharacterized structural features reveal insights into NPC assembly. | Gaoxingyu Huang Yanqing Zhang Xuechen Zhu Chao Zeng Qifan Wang Qiang Zhou Qinghua Tao Minhao Liu Jianlin Lei Chuangye Yan Yigong Shi | 2020 | Cell Research2020，30，6： | 2 |
| 18 | Four COVID-19 Cases of New Variant B.1.351 First Emerging in South Africa in Chinese Passengers on Same Flight-Shenzhen,China,January 2021显示文摘At 04∶50 on January 1,2021,a 36-year-old Chinese project manager(Case A),a 29-year-old Chinese worker(Case B),and a 53-year-old Chinese businessman(Case C)returned from Africa(Case A and B from South Africa and Case C from Lesotho)on the same flight and tested coronavirus disease 2019(COVID-19)RNA positive by real-time polymerase chain reaction(PCR)by Baoan District People’s Hospital.Shenzhen CDC received their oral nasopharyngeal swabs packages from the hospital and retested COVID-19 RNA positive at 09∶50.Meanwhile,Case D. | Cong Cheng Lei Wang Ziquan Lyu Bo Peng Yinghui Li Dongfeng Kong Le Zuo Xiaomin Zhang Chao Yang Weiwen Liu Jia Wan Yijun Tang Junjia He Ying Wen Shule Xu Weihua Wu Ying Chen Guangnan Liu Junjie Xia Xuan Zou Renli Zhang Qinghua Hu Shujiang Mei Tiejian Feng | 2021 | China CDC weekly2021，3，8： | 2 |
| 19 | Extensive game analysis and improvement strategy of DPOS consensus mechanism显示文摘Delegated proof-of-stake(DPOS) consensus mechanism is widely adopted in blockchain platforms, but problems exist in its current applications. In order to explore the security risks in the voting attack of the DPOS consensus mechanism, an extensive game model between nodes was constructed, and it was concluded that the DPOS consensus mechanism relies too much on tokens, and the possibility of node attacks is very high. In order to solve the problems of frequent changes of DPOS consensus mechanism nodes, inactive node voting, excessive reliance on tokens, and malicious nodes, a dynamic, credible, and attack-evading DPOS consensus mechanism was proposed. In addition, the Python simulation results show that the improved Bayesian voting algorithm is effective in calculating node scores. | Wang Lei Zhu Qinghua Li Baozhen | 2021 | The Journal of China Universities of Posts and Telecommunications2021，28，5： | 2 |
| 20 | A Universal Principle to Accurately Synthesize Atomically Dispersed Metal–N_4 Sites for CO_2 Electroreduction显示文摘Atomically dispersed metal-nitrogen sites-anchored carbon materials have been developed as effective catalysts for CO2 electroreduction(CO2 ER),but they still suffer from the imprecisely control of type and coordination number of N atoms bonded with central metal.Herein,we develop a family of single metal atom bonded by N atoms anchored on carbons(SAs-M-N-C,M=Fe,Co,Ni,Cu)for CO2 ER,which composed of accurate pyrrole-type M-N4 structures with isolated metal atom coordinated by four pyrrolic N atoms.Benefitting from atomically coordinated environment and specific selectivity of M-N4 centers,SAs-Ni-N-C exhibits superior CO2 ER performance with onset potential of-0.3 V,CO Faradaic efficiency(F.E.) of 98.5%at-0.7 V,along with low Tafel slope of 115 mV dec-1 and superior stability of 50 h,exceeding all the previously reported M-N-C electrocatalysts for CO2-to-CO conversion.Experimental results manifest that the different intrinsic activities of M-N4 structures in SAs-M-N-C result in the corresponding sequence of Ni> Fe> Cu> Co for CO2 ER performance.An integrated Zn-CO2 battery with Zn foil and SAs-Ni-N-C is constructed to simultaneously achieve CO2-to-CO conversion and electric energy output,which delivers a peak power density of 1.4 mW cm-2 and maximum CO F.E.of 93.3%. | Wanzhen Zheng Feng Chen Qi Zeng Zhongjian Li Bin Yang Lecheng Lei Qinghua Zhang Feng He Xilin Wu Yang Hou | 2020 | Nano-Micro Letters2020，12，9： | 2 |
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