|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Lactobacillus plantarum inhibits epithelial barrier dysfunction and interleukin-8 secretion induced by tumor necrosis factor-a显示文摘AIM: To determine whether Lactobacillus plantarum can modify the deleterious effects of tumor necrosis factor-a (TNF-a) on intestinal epithelial cells. METHODS: Caco-2 cells were incubated with TNF-a alone or in the presence of L. plantarum. Transepithelial electrical resistance was used to measure epithelial barrier function. Interleukin 8 (IL-8) secretion by intestinal epithelial cells was measured using an ELISA. Cellular lysate proteins were immunoblotted using the anti-extracellular regulated kinase (ERK), anti-phospho- ERK and anti-IκB-a. RESULTS: A TNF-a-induced decrease in transepithelial electrical resistance was inhibited by L. plantarum. TNF- a-induced IL-8 secretion was reduced by L. plantarum. L. plantarum inhibited the activation of ERK and the degradation of IκB-a in TNF-a-treated Caco-2 cells. CONCLUSION: Induction of epithelial barrier dysfunction and IL-8 secretion by TNF-a is inhibited by L. plantarum. Probiotics may preserve epithelial barrier function and inhibit the inflammatory response by altering the signal transduction pathway. | Jae Sung Ko Hye Ran Yang Ju Young Chang Jeong Kee Seo | 2007 | World Journal of Gastroenterology2007，13，13： | 18 |
| 2 | Association of Estrogen Receptor I Genetic Polymorphisms with Recurrent Spontaneous Abortion Risk显示文摘 | Xun-Qiang Yin Hong-Mei Ju Qiang Guo Lin Zhao Xiao-Xiao Zhu Ran Wei Zhen Zhang Yun-Hong Zhang Bin Wang Xia Li | 2018 | Chinese Medical Journal2018，，15： | 18 |
| 3 | Consensus on the application of negative pressure wound therapy of diabetic foot wounds显示文摘Because China is becoming an aging society,the incidence of diabetes and diabetic foot have been increasing.Diabetic foot has become one of the main health-related killers due to its high disability and mortality rates.Negative pressure wound therapy(NPWT)is one of the most effective techniques for the treatment of diabetic foot wounds and great progress,both in terms of research and its clinical application,has been made in the last 20 years of its development.However,due to the complex pathogenesis and management of diabetic foot,irregular application of NPWT often leads to complications,such as infection,bleeding and necrosis,that seriously affect its treatment outcomes.In 2020,under the leadership of Burns,Trauma and Tissue Repair Committee of the Cross-Straits Medicine Exchange Association,the writing group for‘Consensus on the application of negative pressure wound therapy of diabetic foot wounds’was established with the participation of scholars from the specialized areas of burns,endocrinology,vascular surgery,orthopedics and wound repair.Drawing on evidence-based practice suggested by the latest clinical research,this consensus proposes the best clinical practice guidelines for the application and prognostic evaluation of NPWT for diabetic foot.The consensus aims to support the formation of standardized treatment schemes that clinicians can refer to when treating cases of diabetic foot. | Shizhao Ji Xiaobin Liu Jie Huang Junmin Bao Zhaohong Chen Chunmao Han Daifeng Hao Jingsong Hong Dahai Hu Yufeng Jiang Shang Ju Hongye Li Zongyu Li Guangping Liang Yan Liu Gaoxing Luo Guozhong Lv Xingwu Ran Zhongmin Shi Juyu Tang Aiping Wang Guangyi Wang Jiangning Wang Xin Wang Bing Wen Jun Wu Hailin Xu Maojin Xu Xiaofei Ye Liangxi Yuan Yi Zhang Shichu Xiao Zhaofan Xia | 2021 | Burns & Trauma2021，9，1： | 17 |
| 4 | Genetically confirmed Wilson disease in a 9-month old boy with elevations of aminotransferases显示文摘Wilson disease (WD) is an autosomal recessive disorder of copper transport caused by alteration of the adenosine triphosphatase 7B gene. It is rare to diagnose WD below the age of three years. Molecular genetic testing is one of the most important diagnostic methods and may confirm the diagnosis in equivocal cases. We report a case of a 9-mo old boy with WD who presented as chronic hepatitis. Genetic analysis showed compound heterozygotes of p.G1186S and c.4006delA. | Joo Whee Kim Jong Hyun Kim Jeong Kee Seo Jae Sung Ko Ju Young Chang Hye Ran Yang Kyung Hoon Kang | 2013 | World Journal of Hepatology2013，5，3： | 11 |
| 5 | Advancement in separation materials for blood purification therapy显示文摘Blood purification refers to the extra corporeal therapies of removing potentially toxic substances, in which blood is circulated through an adsorption system loading separation materials. High-efficient inexpensive separation materials are critical to success. In this review, separation materials such as polymers and nanomaterials are summarized and compared. Combining the advantages of the adsorptive membranes and nanomaterials, organic–inorganic hybrid/blend membranes have been developed explosively. These hybrid/blend membranes have both the characteristics of high permeability, easy fabrication, good biocompatibility of adsorptive membranes, and characteristics of fast adsorption rate and high adsorption capacity of nanomaterials. The preparation and modification methodology of the separation materials is reviewed. For affinity separation materials, the relationship of ligand chemistry, ligand density and pores of the matrix is discussed. This paper also summarizes some interesting applications in separation materials for removal of bilirubin, endotoxin, toxic metal ions, cytokine, etc. | Jia Ju Feixue Liang Xiaoxin Zhang Ran Sun Xiaoguang Pan Xiaoyun Guan Guanning Cui Xuan He Mengyan Li | 2019 | Chinese Journal of Chemical Engineering2019，27，6： | 5 |
| 6 | Genotype patterns and characteristics of PRNP in the Korean population 显示文摘 | Moe Lee S Ran Ju Y Choi BY | 2012 | Prion2012，6，4： | 1 |
| 7 | A personalized recommendation procedure for Inter- net shopping support显示文摘 | Jae Kyeong Kim Yoon Ho Cho Woo Ju Kim Je Ran Kim | | 0，，02： | 1 |
| 8 | Progress and Developing Trend of Purging Plugs for Refining Ladle显示文摘Damage reasons of purging plugs for refining ladle and research progress on thermal shock resistance of corundum- spinel purging plugs were summarized. Research achievements and application results of nonoxides bonded corundum purging plugs for refining ladle were briefly reviewed. The further research and developing trend of purging plugs was proposed. | ZHANG Ju SUN Xiaogai JIA Quanli WU Ran | 2014 | China's Refractories2014，23，2： | 1 |
| 9 | Interleukin-10 receptor mutations in children with neonatal-onset Crohn’s disease and intractable ulcerating enterocolitis显示文摘 | Jung Ok Shim Solha Hwang Hye Ran Yang Jin Soo Moon Ju Young Chang Jae Sung Ko Sung Sup Park Gyeong-Hoon Kang Woo Sun Kim Jeong Kee Seo | 2013 | European Journal of Gastroenterology & Hepatology2013，，10： | 1 |
| 10 | The influence of the pulsatility of the blood flow on the extent of platelet adhesion显示文摘 | Xiao Min Zhao Ya Ping Wu Hong Xin Cai Ran Wei Ton Lisman Ji Ju Han Zuo Li Xia Philip G. de Groot | 2007 | Thrombosis Research2007，，6： | 1 |
| 11 | A study on coagulate method control expansion of sludge 显示文摘 | Zhao Yuhua Ju Ran Fu Jinxiang | 2005 | Shenyang Architecture University Transaction2005，21，6： | 1 |
| 12 | The mechanism of enhancement on oral absorption of paclitaxel by N-octyl-O-sulfate chitosan micelles显示文摘 | Ran Mo Xiang Jin Nan Li Caoyun Ju Minjie Sun Can Zhang Qineng Ping | 2011 | Biomaterials2011，，20： | 1 |
| 13 | Induced Plasticity of a Brittle(La,Ce)-Based Bulk Metallic Glass by Surface Corrosion显示文摘Unexpected facture without any room-temperature plasticity severely limits potential structural applications of bulk metallic glasses(BMGs), especially La-, Mg- and Fe-based ones. In this study, a simple free corrosion method was provided to improve the plasticity of a brittle(La, Ce)-based BMG by the introduction of high-density corrosion defects on the surface. The influences of immersing time in 0.1 mol/L H2SO4 aqueous solution on the surface morphology and mechanical properties of the BMG were evaluated. With increasing immersing time from 5 to 30 min, the degree of surface corrosion increased obviously, and the distribution of corrosion defects became more homogenous. In the samples, the yielding phenomenon and certain plasticity appeared up to 0.3% after the surface treatment. The yielding and plasticity can be attributed to easier nucleation of shear bands on the defect surface rather than on the glabrous surface. The results provided a novel method to improve the plasticity of BMGs. | Ji-Juan Liu Ran Li Lian-Xiang Fang Ju Wang Tao Zhang | 2016 | Acta Metallurgica Sinica(English Letters)2016，29，2： | 1 |
| 14 | Estrogen stimulates the neuronal differentiation of human umbilical cord blood mesenchymal stem cells (CD34?)显示文摘 | Ji Hye Kang Chae Kwan Lee Ju Ran Kim Seong Jin Yu Jong Hee Jo Byung-Rok Do Hae Kwon Kim Sung Goo Kang | 2007 | NeuroReport2007，，1： | 1 |
| 15 | A personalized recommendation procedure for Internet shopping support显示文摘 | JAE KYEONG KIM YOON HO CHO WOO JU KIM JE RAN KIM JI HAE SUH | 2002 | Electronic Commerce Research and Applications2002，，1： | 1 |
| 16 | The accuracy of probe-based confocal endomicroscopy versus conventional endoscopic biopsies for the diagnosis of superficial gastric neoplasia (with videos)显示文摘 | Gene Hyun Bok Seong Ran Jeon Joo Young Cho Jun-Hyung Cho Woong Cheul Lee So Young Jin In Ho Choi Hyun Gun Kim Tae Hee Lee Eui Ju Park | 2013 | Gastrointestinal Endoscopy2013，，6： | 1 |
| 17 | Constraining self-interacting dark matter with the full dataset of PandaX-II显示文摘Self-interacting dark matter(SIDM)is a leading candidate proposed to solve discrepancies between predictions of the prevailing cold dark matter theory and observations of galaxies.Many SIDM models predict the existence of a light force carrier that mediates strong dark matter self-interactions.If the mediator couples to the standard model particles,it could produce characteristic signals in dark matter direct detection experiments.We report searches for signals of SIDM models with a light mediator using the full dataset of the PandaX-II experiment,basing on a total exposure of 132 tonne-days.No significant excess over background is found,and our likelihood analysis leads to a strong upper limit on the dark matter-nucleon coupling strength.We further combine the PandaX-II constraints and those from observations of the light element abundances in the early universe,and show that direct detection and cosmological probes can provide complementary constraints on dark matter models with a light mediator. | Jijun Yang Abdusalam Abdukerim Wei Chen Xun Chen Yunhua Chen Chen Cheng Xiangyi Cui Yingjie Fan Deqing Fang Changbo Fu Mengting Fu Lisheng Geng Karl Giboni Linhui Gu Xuyuan Guo Ke Han Changda He Shengming He Di Huang Yan Huang Ran Huo Yanlin Huang Zhou Huang Xiangdong Ji Yonglin Ju Shuaijie Li Qing Lin Huaxuan Liu Jianglai Liu Xiaoying Lu Wenbo Ma Yugang Ma Yajun Mao Yue Meng Nasir Shaheed Kaixiang Ni Jinhua Ning Xuyang Ning Xiangxiang Ren Changsong Shang Guofang Shen Lin Si Andi Tan Anqing Wang Hongwei Wang Meng Wang QiuHong Wang Siguang Wang Wei Wang Xiuli Wang Zhou Wang Mengmeng Wu Shiyong Wu Weihao Wu Jingkai Xia Mengjiao Xiao Xiang Xiao Pengwei Xie Binbin Yan Yong Yang Chunxu Yu Hai-Bo Yu Jumin Yuan Ying Yuan Xinning Zeng Dan Zhang Tao Zhang Li Zhao Qibin Zheng Jifang Zhou Ning Zhou Xiaopeng Zhou | 2021 | Science China(Physics,Mechanics & Astronomy)2021，64，11： | 0 |
| 18 | Advances in nuclear detection and readout techniques显示文摘“A Craftsman Must Sharpen His Tools to Do His Job,”said Confucius.Nuclear detection and readout techniques are the foundation of particle physics,nuclear physics,and particle astrophysics to reveal the nature of the universe.Also,they are being increasingly used in other disciplines like nuclear power generation,life sciences,environmental sciences,medical sciences,etc.The article reviews the short history,recent development,and trend of nuclear detection and readout techniques,covering Semiconductor Detector,Gaseous Detector,Scintillation Detector,Cherenkov Detector,Transition Radiation Detector,and Readout Techniques.By explaining the principle and using examples,we hope to help the interested reader underst and this research field and bring exciting information to the community. | Rui He Xiao‑Yang Niu Yi Wang Hong‑Wei Liang Hong‑Bang Liu Ye Tian Hong‑Lin Zhang Chao‑Jie Zou Zhi‑Yi Liu Yun‑Long Zhang Hai‑Bo Yang Ju Huang Hong‑Kai Wang Wei‑Jia Han Bei Cao Gang Chen Cong Dai Li‑Min Duan Rui‑Rui Fan Fang‑Fa Fu Jian‑Hua Guo Dong Han Wei Jiang Xian‑Qin Li Xin Li Zhuo‑Dai Li Yu‑Tie Liang Shun Liao De‑Xu Lin Cheng‑Ming Liu Guo‑Rui Liu Jun‑Tao Liu Ze Long Meng‑Chen Niu Hao Qiu Hu Ran Xiang‑Ming Sun Bo‑Tan Wang Jia Wang Jin‑Xiang Wang Qi‑Lin Wang Yong‑Sheng Wang Xiao‑Chuan Xia Hao‑Qing Xie He‑Run Yang Hong Yin Hong Yuan Chun‑Hui Zhang Rui‑Guang Zhao Ran Zheng Cheng‑Xin Zhao | 2023 | Nuclear Science and Techniques2023，34，12： | 0 |
| 19 | Progress and challenges in dicarboxylation with CO_(2)显示文摘Dicarboxylic acids,which are appealing structural motifs in organic synthesis and exist widely in bioactive compounds,have been widely used as important monomers in the polymer industry to construct valuable materials.The dicarboxylation with CO_(2)provides a convenient and potent way to furnish value-added dicarboxylic acids via the chemical fixation of two CO_(2)molecules.Beyond any doubt,the development of dicarboxylation,especially the dicarboxylation of bulk chemicals,might represent a promising prospect in CO_(2)capture and utilization(CCU).In this review,we critically summarized and comprehensively reviewed the advances made in the past decades in dicarboxylation with CO_(2)under electro-,photo-and transition metal-mediated/catalytic systems.Moreover,the advantages and limitations of such dicarboxylation reactions are pointed out to unravel further development for future scientific and industrial advances in dicarboxylation with CO_(2)to synthesize dicarboxylic acids in high selectivity and efficiency. | Chuan-Kun Ran Han-Zhi Xiao Li-Li Liao Tao Ju Wei Zhang Da-Gang Yu | 2023 | National Science Open2023，2，2： | 0 |
| 20 | Magnifying endoscopy for the diagnosis of specialized intestinal metaplasia in short-segment Barrett's esophagus显示文摘AIM:To determine whether magnified observation of short-segment Barrett’s esophagus(BE)is useful for the detection of specialized intestinal metaplasia(SIM).METHODS:Thirty patients with suspected short-segment BE underwent magnifying endoscopy up to×80.The magnified images were analyzed with respect to their pit-patterns,which were simultaneously classified into five epithelial types[Ⅰ(small round),Ⅱ(straight),Ⅲ(long oval),Ⅳ(tubular),Ⅴ(villous)]by Endo’s classification.Then,a 0.5%solution of methylene blue(MB)was sprayed over columnar mucosa.The patterns of the magnified image and MB staining were analyzed.Biopsies were obtained from the regions previously observed by magnifying endoscopy and MB chromoendoscopy.RESULTS:Three of five patients with a typeⅤ(villous)epithelial pattern had SIM,whereas 21 patients with a non-typeⅤepithelial patterns did not have SIM.The sensitivity,specificity,accuracy,positive predictive value,and negative predictive value of pit-patterns in detecting SIM were 100%,91.3%,92.3%,60%and100%,respectively(P=0.004).Three of the 12 patients with positive MB staining had SIM,whereas 14patients with negative MB staining did not have SIM.The sensitivity,specificity,accuracy,positive predictive value,and negative predictive value of MB staining in detecting SIM were 100%,60.9%,65.4%,25%and100%,respectively(P=0.085).The specificity and accuracy of pit-pattern evaluation were significantly superior compared with MB staining for detecting SIM by comparison with the exact McNemar’s test(P=0.0391).CONCLUSION:The magnified observation of a shortsegment BE according to the mucosal pattern and its classification can be predictive of SIM. | Nam Seok Ham Jae Young Jang Sung Woo Ryu Ji Hye Kim Eui Ju Park Woong Cheul Lee Kwang Yeun Shim Soung Won Jeong Hyun Gun Kim Tae Hee Lee Sung Ran Jeon Jun Hyung Cho Joo Young Cho So Young Jin Ji Sung Lee | 2013 | World Journal of Gastroenterology2013，19，41： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员