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| 1 | Recent temperature increase recorded in an ice core in the source region of Yangtze River显示文摘Interests on climate change in the source region of Yangtze River have been raised since it is a region with the greatest warming over the Tibetan Plateau (TP). A 70-year history of precipitation δ^(18)O has been recovered using an ice core record retrieved in a plat portion of the firn area in the Guoqu Glacier (33°34′37.8″N, 91°10′35.3″E, 5720 m a.s.l.), Mt. Geladaindong (the source region of Yangtze River), in November, 2005. By using a significant positive relationship between ice core δ^(18)O record and summer air temperature (July to September) from the nearby meteorological stations, a history of summer air temperature has been reconstructed for the last 70 years. Summer temperature was relatively low in 1940s and high in 1950s to the middle of 1960s. The lowest temperature occurred in the middle of 1970s. Temperature was low in 1980s and dramatically increased since 1990s, keeping the trend to the begin-ning of the 21st century. The warming rate recorded in the ice core with 0.5℃/10 a since 1970s is much higher that that in the central TP and the Northern Hemisphere (NH), and it becomes 1.1℃/10 a since 1990s which is also higher than these from the central TP and the NH, reflecting an accelerated warm-ing and a more sensitive response to global warming in the high elevation region. | KANG ShiChang ZHANG YongJun QIN DaHe REN JiaWen ZHANG QiangGong Bjorn GRIGHOLM Paul A. MAYEWSKI | 2007 | Chinese Science Bulletin2007，52，6： | 27 |
| 2 | Oridonin inhibits BxPC-3 cell growth through cell apoptosis显示文摘Oridonin,从繁体中文植物 Rabdosia rubescens 提取的 ent-kaurene diterpenoid,有多重生物、药品的功能并且临床上被使用许多年了。当 oridonin 的 antitumor 功能被证据的众多的线支持了时,它的 anticancer 机制很好没被记录。在这研究,胰腺的癌症房间线 BxPC-3 被用作一个模型通过在房间生存能力上检验它的效果调查 oridonin 的可能的 anticancer 机制。结果证明 oridonin 在一个时间依赖者和剂量依赖者举止影响了房间生存能力。在到不同 oridonin 集中的暴露以后,生长率和 BxPC-3 房间的房间周期拘捕显著地与未经治疗的房间相比被减少,建议它增长抑制上的效果。由西方的污点分析的详细发信号的小径分析表明低剂量的 oridonin 治疗由起来调整的 p53 和下面调整的 cyclin 依赖的 kinase 禁止了 BxPC-3 房间增长 1 (CDK1 ) ,它在 G2/M 阶段导致了房间周期拘捕。高剂量的 oridonin 不仅在 G2/M 阶段逮捕了 BxPC-3 房间而且在 S 阶段导致了房间累积,大概,通过 H2AX,起来规定和 DNA 损坏。另外,我们的结果证明房间 subpopulation 在 oridonin 治疗以后与 propidium 碘化物被染色。蛋白质 quantification 显示出 poly 劈开那(自动数据处理核糖) 聚合酶(PARP ) 表示在一个高剂量的 oridonin 处理以后被增加,特别在长期的暴露以后。在表情也是的房间, apoptosis 开始者 caspase-3 和 caspase-7 显著地增加了的 BxPC-3 由撤销 PARP 的增加的水平伴随了,建议调停 caspase 的 apoptosis 贡献了房间死亡。 | Bin Xu Wen Shen Xing Liu Ting Zhang Jun Ren Yongjun Fan Jian Xu | 2015 | Acta Biochimica et Biophysica Sinica2015，47，3： | 11 |
| 3 | Generation of hircine-induced pluripotent stem cells by somatic cell reprogramming显示文摘 | Jiangtao Ren Yongjun Pak Lixiazi He Lei Qian Yijun Gu Hui Li Lingjun Rao Jing Liao Chun Cui Xun Xu Jinqiu Zhou Hakchol Ri Lei Xiao | 2011 | Cell Research2011，21，5： | 10 |
| 4 | Mutation of kri1l causes definitive hematopoiesis failure via PERK-dependent excessive autophagy induction显示文摘 | Xiao-E Jia Ke Ma Tao Xu Lei Gao Shuang Wu Cong Fu Wenjuan Zhang Zhizhang Wang Kaiyu Liu Mei Dong Changbin Jing Chunguang Ren Zhiwei Dong Yi Chen Yi Jin Qiuhua Huang Xing Chang Min Deng Li Li Lingfei Luo Jun Zhu Yongjun Dang Hung-Chun Chang Leonard I Zon Yi Zhou Saijuan Chen Weijun Pan | 2015 | Cell Research2015，25，8： | 8 |
| 5 | Cloning,expression and binding specificity analysis of odorant binding protein 3 of the lucerne plant bug,Adelphocoris lineolatus(Goeze)显示文摘Credible evidence shows that odorant binding proteins(OBPs)are required for insect olfaction perception and play a key role in transporting hydrophobic odorants across the sensillum lymph to the olfactory receptors(ORs).In the present study,a novel OBP(AlinOBP3)gene from the lucerne plant bug,Adelphocoris lineolatus,was cloned and expressed.The expression pattern of AlinOBP3 was evaluated by qPCR,which indicated that AlinOBP3 was dominantly expressed in antennae.The binding properties of AlinOBP3 with 9 cotton volatiles and 5 sex pheromone analogs were measured by fluorescence competitive binding assays with the fluorescence probe 1-NPN.The results revealed that of 9 cotton volatiles,Myrcene,β-Ocimene and α-Phellandrene can bind with AlinOBP3.α-Phellandrene especially bound to AlinOBP3 with a high binding affinity,with a dissociation constant of 56.68 μmol/L.Of the 5 sex pheromone analogs,Hexyl butyrate had the strongest binding affinity with AlinOBP3,with a dissociation constant as 59.53 μmol/L.Butyl butyrate,trans-2-Hexenyl butyrate and Ethyl butyrate had medium binding affinities with AlinOBP3,with dissociation constants of 227.39,108.77 and 143.47 μmol/L,respectively.The results suggest that AlinOBP3 might be a pheromone binding protein(PBP)with a dual-function for the perception of sex pheromones and plant volatiles. | GU ShaoHua SUN Yang REN LiYan ZHANG XueYing ZHANG YongJun WU KongMing GUO YuYuan | 2010 | Chinese Science Bulletin2010，55，34： | 7 |
| 6 | Digital Continuity Guarantee Approach of Electronic Record Based on Data Quality Theory显示文摘Since the British National Archive put forward the concept of the digital continuity in 2007,several developed countries have worked out their digital continuity action plan.However,the technologies of the digital continuity guarantee are still lacked.At first,this paper analyzes the requirements of digital continuity guarantee for electronic record based on data quality theory,then points out the necessity of data quality guarantee for electronic record.Moreover,we convert the digital continuity guarantee of electronic record to ensure the consistency,completeness and timeliness of electronic record,and construct the first technology framework of the digital continuity guarantee for electronic record.Finally,the temporal functional dependencies technology is utilized to build the first integration method to insure the consistency,completeness and timeliness of electronic record. | Yongjun Ren Jian Qi Yaping Cheng Jin Wang Osama Alfarraj | 2020 | Computers, Materials & Continua2020，，6： | 3 |
| 7 | Distribution of sterane maturity parameters in a lacustrine basin and their control factors:A case study from the Dongying Sag,East China显示文摘Fifty samples from the source rocks in Member 3 and Member 4 of the Paleogene Shahejie Formation in the Bohai Bay Basin,East China,were analyzed to investigate the distribution,evolution of the molecular maturity ratios C 29 ββ/(ββ+αα) and C 29 20S/(20S+20R) and their control factors in the natural geological profile and sequence.The results showed that progressive changes in molecular maturity parameters are associated with major changes in thermal evolution of related biomarkers.Increases in the C 29 ββ/(ββ+αα) and C 29 20S/(20S+20R) ratios result from the difference in the relative rate between generation and thermal degradation of isomers involved.The samples from a hyper-saline environment below 3.5 km in which evaporitic rocks deposited shows high response of Sr/Ba,Sr/Ca,Fe/Mn,Pr/n-C 17,Ph/n-C 18 and gammacerane and low response of Pr/Ph.There presents negative reversal of biomarker maturity C 29 ββ/(ββ+αα),C 29 20S/(20S+20R) and Ts/(Ts+Tm) in the samples from hypersaline environment,reflecting that the gypsum-halite have negative effect on the isomerization of biomarker and thermal evolution of organic matter.The minerals in evaporites also retard the conventional thermal indicators including vitrinite reflectance (R o) and pyrolysis peak temperature T max at the depth below 3.4 km (i.e.>3.4 km),and these parameters also show the inhibition from overpressure in the range of 2.4-3.4 km.This result will be helpful in the interpretation and application of molecular maturity parameters for similar saline lacustrine basins. | Chen Zhonghong Zha Ming Jin Qiang Ren Yongjun | 2011 | Petroleum Science2011，8，3： | 3 |
| 8 | Fuzzy conditional proxy re-encryption显示文摘Weng et al.introduced the notion of conditional proxy re-encryption(C-PRE),whereby only the ciphertext satisfying one condition set by Alice can be re-encrypted by the proxy.To achieve more fine-grained delegation on the condition set,we introduce a new cryptographic primitive called fuzzy conditional proxy re-encryption(FC-PRE) in which we view conditions in C-PRE as a set of descriptive keywords.A FC-PRE scheme allows for a proxy with the re-encryption key for a conditional keyword set,W,to re-encrypt a ciphertext encrypted with a conditional keyword set,W,if and only if W and W are close to each other as measured by the 'set overlap' distance metric.Therefore,our system allows a certain amount of error-tolerance in the conditions.We formalize the FC-PRE security model by incorporating the advantages in previous C-PRE.Finally,we present an efficient construction of FC-PRE scheme,and prove its CCA-security under the wellstudied decisional bilinear Diffie-Hellman(DBDH) assumption in the random oracle model. | FANG LiMing WANG JianDong GE ChunPeng REN YongJun | 2013 | Science China(Information Sciences)2013，56，5： | 2 |
| 9 | Megacrysts in the Cenozoic basalt of the Tuoyun Basin,Southwest Tianshan显示文摘Abundant megacrysts of clinopyroxene, amphibole, anorthoclase, and phlogopite are found together with deep-seated xenoliths in the Cenozoic basalt of the Tuoyun Basin, Southwest Tianshan. The megacrysts are mainly in the cone sheet formed at the early stage of the volcanic activity. Clinopyrox-ene megacrysts are located in the lower part of the profile, with amphibole and phlogopite megacrysts in the middle part and anorthoclase megacrysts in the upper part. The crystal integrity, absence of de-formation fabric and their relation to the host basalt suggest that they were crystallized from the host magma and quickly transported to the surface. The mineralogical studies imply that the clinopyroxene megacrysts are of Al-augite with higher Al2O3 (>9%). Amphibole megacrysts are kaersutite rich in TiO2 (>4.5%). Sulfide inclusions such as pyrrhotite occur in some clinopyroxene and amphibole megacrysts. Thermodynamic calculations reveal that pyroxene megacrysts formed under the temperature of 1185.85―1199.85℃ and the pressure between 1.53 and 1.64 GPa comparable to the crust-mantle boundary and amphibole megacrysts crystallized under the pressure of around 0.85 GPa, temperature about 1000℃ comparable to the depth of 30 km. Anorthoclase megacrysts crystallized under the pressure between 0.8―1 GPa,temperature about 900℃.The absence of Ti-rich inclusions such as rutile can be considered as an evidence of quick magma ascending. The P-T conditions estimated via py-roxene megacrysts and phenocrysts compose a P-T path with a steep slope. It can be considered as another evidence of quick magma ascending. However, the estimated temperatures for amphibole megacrysts are markedly lower than those for pyroxene megacrysts given the same pressure. It probably shows that the amphiboles have crystallized at the vanguard of magma and under the vola-tile-rich condition. Thus, we can conclude that the Cenozoic basalts are produced in an extensional tectonic setting and the processes governing crystallization and ascending of the megacrysts are very complex. | LÜ YongJun LUO ZhaoHua REN ZhongBao LIANG Tao | 2007 | Science China Earth Sciences2007，50，1： | 2 |
| 10 | Treating acute large vessel occlusion stroke:to bridge or not to bridge?显示文摘Hot debates exist regarding whether patients who had an acute large vessel occlusion stroke(LVOS)can skip tissue plasminogen activator(tPA)and go directly to thrombectomy in comprehensive stroke centres.Three head-to-head randomised clinical trials(RCTs)of direct endovascular treatment(dEVT)versus bridge therapy(BT)with intravenous alteplase have been recently completed in the Asian population.The DIRECT-MT(Direct Intraarterial Thrombectomy in Order to Revascularize Acute Ischemic Stroke Patients with Large Vessel Occlusion Efficiently in Chinese Tertiary Hospitals:a Multicenter Randomized Clinical Trial)Study randomly enrolled 656 patients who had an acute ischaemic stroke with anterior circulation LVOS across 41 large teaching hospitals in China to receive BT or dEVT within 4.5 hours after symptom onset. | Yunyun Xiong Yuesong Pan Raul G Nogueira Zeguang Ren Tudor G Jovin Yongjun Wang | 2021 | Stroke & Vascular Neurology2021，6，3： | 1 |
| 11 | Pay-as-bid versus marginal pricing-part Ⅰ: Strategic generator offers显示文摘 | Yongjun Ren Galiana F D | 2004 | IEEE Transaction on Power Systems2004，19，4： | 1 |
| 12 | Dynamic changes of renal cortical blood perfusion before and after percutaneous transluminal renal artery stenting in patients with severe atherosclerotic renal artery stenosis显示文摘Background:This study aims to observe the dynamic changes of renal artery(RA)disease and cortical blood perfusion(CBP)evaluated by contrast-enhanced ultrasound(CEUS)after percutaneous transluminal renal artery stenting(PTRAS)in patients with severe atherosclerotic renal artery stenosis(ARAS)and to analyze the relationship between CBP and prognosis.Methods:This was a single-center retrospective cohort study.A total of 98 patients with unilateral severe ARAS after successful PTRAS in Beijing Hospital from September 2017 to September 2020 were included.According to renal glomerular filtration rate(GFR)detected by radionuclide imaging at 12 months after PTRAS,all patients were divided into the poor prognosis group(n=21,GFR decreased by≥20%compared with baseline)and the control group(n=77,GFR decreased by<20%or improved compared with baseline).Renal artery stenosis was diagnosed by digital subtraction angiography,and renal CBP was evaluated by CEUS using TomTec Imaging Systems(Germany)before PTRAS,at 6 months and 12 months after discharge.The receiver operating characteristic(ROC)curve with area under the curve(AUC)was used to analyze the predictive value of CBP parameters,including area under ascending curve(AUC1),area under the descending curve(AUC2),rising time(RT),time to peak intensity(TTP),maximum intensity(IMAX),and mean transit time(MTT)for poor prognosis.Results:Among the 98 patients,there were 52 males(53.1%),aged 55–74 years old,with an average age of 62.1±8.7 years,and an average artery stenosis of 82.3±12.9%.The poor prognosis group was associated with significantly increased incidence of diabetes(76.2%vs.41.6%),and lower levels of GFR of the stenotic kidney(21.8 mL/min vs.25.0 mL/min)and total GFR(57.6 mL/min vs.63.7 mL/min)(all P<0.05),compared with the control group(P<0.05).In addition,the rate of RA restenosis was significantly higher in the poor prognosis group than in the control group(9.5%vs.0,χ^(2)=9.462,P=0.002).Compared with the control group,the poor prognosis group was associated with significantly decreased baseline AUC1 and AUC2,and extended duration of TTP and MTT(P<0.05).At 6 months and 12 months of follow-up,patients in the control group were associated with markedly increased AUC1,AUC2,and IMAX,and shorter duration of RT and MTT(P<0.05).The ROC curve showed that the predictive values of AUC1,AUC2,RT,TTP,IMAX,and MTT for poor prognosis were 0.812(95%CI:0.698–0.945),0.752(95%CI:0.591–0.957),0.724(95%CI:0.569–0.961),0.720(95%CI:0.522–0.993),0.693(95%CI:0.507–0.947),and 0.786(95%CI:0.631–0.979),respectively.Conclusions:Preoperative renal CBP in severe ARAS patients with poor prognosis is significantly reduced,and does not show significant improvement after stent treatment over the first year of follow-up.The parameter AUC1 may be a good predictor for renal dysfunction after PTRAS in severe ARAS patients.Trial Registration:ChiCTR.org.cn,ChiCTR1800016252. | Na Ma Yan Li Siyu Wang Mengpu Li Yongjun Li Hu Ai Hui Zhu Yang Wang Fajin Guo Junhong Ren | 2022 | Chinese Medical Journal2022，，13： | 1 |
| 13 | Real-time Optimal Reactive Power Dispatch Using Multi-agent Technique 显示文摘 | Zhang Yongjun Ren Zhen | 2004 | Electric Power Systems Research2004，69，3： | 1 |
| 14 | (E)-β-Farnesene synthase genes affect aphid (Myzus persicae) infestation in tobacco (Nicotiana tabacum)显示文摘 | Xiudao Yu Huw Jones Youzhi Ma Genping Wang Zhaoshi Xu Baoming Zhang Yongjun Zhang Guangwei Ren John Pickett Lanqin Xia | 2012 | Functional & Integrative Genomics2012，，1： | 1 |
| 15 | Pay-as-bid versus marginal pricing-part Ⅰ: strategic generator offers 显示文摘 | Ren Yongjun Galiana Francisco D | 2004 | IEEE Trans on Power Systems2004，19，4： | 1 |
| 16 | Designated-verifier provable data possession in public cloud storage 显示文摘 | Ren Yongjun Xu Jiang Wang Jin | 2013 | International Journal of Security and Its Applications2013，7，6： | 1 |
| 17 | Growth and Distribution of Amphioctopus fangsiao(d'Orbigny, 1839–1841) in Haizhou Bay, Yellow Sea显示文摘Octopus fisheries have prospered in many areas of the world ocean over the last six decades. Despite degradation and overexploitation of Chinese coastal ecosystems, octopus has become a stable Chinese domestic fishery species. Among the octopus species in the Bohai and Yellow, East and South China Seas, Amphioctopus fangsiao(d'Orbigny [in Férussac & d'Orbigny], 1839–1841) plays an increasingly important role both economically and ecologically. However, no systematic research has been conducted on its biology and population dynamics in the China Seas. In this study, we characterized the growth and distribution of A. fangsiao in Haizhou Bay, Yellow Sea based on four years of trawl survey data. As the results, A. fangsiao is characterized by allometric growth and an overall sex ratio of 0.97 with a slight male bias. Small octopus can be observed through a whole year, suggesting that A. fangsiao may have an extended or continuous spawning season. A. fangsiao may migrate short distances along with seasonal changes and coastal currents, considering they overwinter in the offshore water and spawn in the inshore water. In addition to fishing pressure, annual variations in the population structure and biomass appeared to be influenced by ambient water temperature. These results provide basic biological information for a better understanding of the population dynamics and the ecological importance of A. fangsiao. | PANG Yumeng TIAN Yongjun FU Caihong REN Yiping WAN Rong | 2020 | Journal of Ocean University of China2020，19，5： | 1 |
| 18 | 显示文摘 | Liang Jie Chen Yongjun Ren Xuehong | 2007 | Ind Eng Chem Res2007，46，20： | 1 |
| 19 | Discussion on Influencing Factors of Shale Pores Development显示文摘1 Introduction From geological point of view,the development of shale pore is dually controlled by external and internal factors.The external factors include tectonic position,tectonic stress,sedimentary diagenesis and high abnormal pressure caused by hydrocarbon generation;internal factors include organic carbon content,maturity | LIU Yang WANG Maozhen SHI Meng REN Yongjun | 2015 | Acta Geologica Sinica(English Edition)2015，89，A01： | 1 |
| 20 | Real-time optimal reactive power dispatch using multi-agent technique显示文摘 | Zhang Yongjun Ren Zhen | 2004 | Electric Power Systems Research2004，69，3： | 1 |
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