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| 1 | Effect of Different Dietary Protein and Lipid Levels on the Growth,Body Composition,and Intestinal Digestive Enzyme Activities of Juvenile Yellow Drum Nibea albiflora(Richardson)显示文摘An 8-week feeding trial was conducted to determine the optimal dietary protein-to-lipid ratio for juvenile Nibea albiflora with an initial weight of(11.76 ± 0.20) g.Nine experimental diets containing different concentrations of protein(40%,47%,or 54%) and lipids(5%,9%,or 13%) in a 3 × 3 factorial experimental design were tested in triplicate groups of fish,while the protein-to-energy(P/E) ratios of the diets varied in the range of 19.74–28.32 mg k J^(-1).Results showed that fish fed diets containing 9% or 13% lipids with 54% protein exhibited significantly higher weight gains and specific growth rates than those fed other diets.The feed conversion rate of fish fed the diet with 40% protein and 5% lipids was significantly poorer than that of fish fed other diets.The protein efficiency rate of fish fed diets with 5% lipids was significantly lower than that of fish fed 9% or 13% lipid diets.Carcass lipid and energy contents were positively correlated with dietary lipid level regardless of protein level.Fish fed a 54% protein diet showed the highest trypsin activity.The intestinal lipase activity of fish fed the diet containing 13% lipids was significantly higher than that of fish fed 5% or 9% lipid diets.These results demonstrate the high protein dietary requirements of N.albiflora.A diet containing 54% protein and 9%–13% lipids with a P/E ratio of 26.2–27.81 mg protein k J^(-1) can be considered optimal for juvenile N.albiflora. | WANG Ligai HU Shenyu LOU Bao CHEN Dongxing ZHAN Wei CHEN Ruiyi LIU Feng XU Dongdong | 2018 | Journal of Ocean University of China2018，17，5： | 4 |
| 2 | Monte Carlo simulation of scintillation crystal detector for formation element logging显示文摘Formation elements logging is a neutron gamma spectroscopy logging technique used to acquire the content of elements and minerals by recording the gamma ray produced by the reaction of neutron and elemental nucleus in the formation. It has a wide usage in discriminating complex lithology and evaluating unconventional reservoir. The Monte Carlo simulation model of formation elements logging tool is established in this paper, with which the effects of tool parameters including the material and length of the scintillation crystal and source spacing on logging responses are modeled. The results show that the energy response of LaBr_3: Ce crystal is better than others, and the detection efficiency increases with the crystal length but decrease with source spacing. The above results may be used as a reference for optimizing the tool structure design. | HAN Ruiyi WANG Zhuwen | 2019 | Global Geology2019，22，2： | 2 |
| 3 | Fe-containing magnetic ionic liquid as an effective catalyst for the glycolysis of poly(ethylene terephthalate) 显示文摘 | Wang Hui Ruiyi Yan Zengxi Li | 2010 | Catalysis Communications2010，11，： | 1 |
| 4 | Effects of Pb and Mg doping in Al 2 O 3 -supported Pd catalyst on direct oxidative esterification of aldehydes with alcohols to esters显示文摘 | Yanyan Diao Ruiyi Yan Suojiang Zhang Pu Yang Zengxi Li Lei Wang Haifeng Dong | 2009 | Journal of Molecular Catalysis A Chemical2009，，1： | 1 |
| 5 | Multi-objective topology and sizing optimization of truss structures based on adaptive multi-island search strategy显示文摘 | SU Ruiyi WANG Xu GUI Liangjin | 2011 | Structural and Multidisciplinary Optimization2011，43，2： | 1 |
| 6 | Multi-objective topology and sizing optimization of truss structures based on adaptive multi-island search strategy 显示文摘 | SU Ruiyi Wang Xu Gui Liangjin | 2011 | Struc and Multidisciplinary Opti2011，43，2： | 1 |
| 7 | Reduced smooth muscle-fibroblasts transformation potentially decreases intestinal wound healing and colitis-associated cancer in ageing mice显示文摘Cancer and impaired tissue wound healing with ageing are closely related to the quality of life of the elderly population.Given the increased incidence of cancer and the population ageing trend globally,it is very important to explore how ageing impairs tissue wound healing and spontaneous cancer.In a murine model of DSS-induced acute colitis and AOM/DSS-induced colitis-associated cancer(CAC),we found ageing significantly decreases intestinal wound healing and simultaneous CAC initiation,although ageing does not affect the incidence of AOM-induced,sporadic non-inflammatory CRC.Mechanistically,reduced fibroblasts were observed in the colitis microenvironment of ageing mice.Through conditional lineage tracing,an important source of fibroblasts potentially derived from intestinal smooth muscle cells(ISMCs)was identified orchestrating intestinal wound healing and CAC initiation in young mice.However,the number of transformed fibroblasts from ISMCs significantly decreased in ageing mice,accompanied by decreased intestinal wound healing and decreased CAC initiation.ISMCs-fibroblasts transformation in young mice and reduction of this transformation in ageing mice were also confirmed by ex-vivo intestinal muscular layer culture experiments.We further found that activation of YAP/TAZ in ISMCs is required for the transformation of ISMCs into fibroblasts.Meanwhile,the reduction of YAP/TAZ activation in ISMCs during intestinal wound healing was observed in ageing mice.Conditional knockdown of YAP/TAZ in ISMCs of young mice results in reduced fibroblasts in the colitis microenvironment,decreased intestinal wound healing and decreased CAC initiation,similar to the phenotype of ageing mice.In addition,the data from intestine samples derived from inflammatory bowel disease(IBD)patients show that activation of YAP/TAZ also occurs in ISMCs from these patients.Collectively,our work reveals an important role of the ageing stromal microenvironment in intestinal wound healing and CAC initiation.Furthermore,our work also identified a potential source of fibroblasts involved in colitis and CAC. | Yi Liu Yanhong Ji Ruiyi Jiang Chao Fang Gang Shi Lin Cheng Yinan Zuo Yixin Ye Xiaolan Su Junshu Li Huiling Wang Yuan Wang Yi Lin Lei Dai Shuang Zhang Hongxin Deng | 2023 | Signal Transduction and Targeted Therapy2023，8，9： | 0 |
| 8 | Pregnancy Loss in Relation to the Risks of Female-Specific Cancers in a Population-Based Cohort and Mendelian Randomization Study — China, 2004–2017显示文摘Summary What is already known about this topic?Limited evidence exists regarding the relationship between pregnancy loss and female-specific cancers within the Chinese population from prospective cohort studies.What is added by this report?Terminations were associated with a 13%lower risk of endometrial cancer,whereas stillbirths were related to an 18%higher risk of cervical cancer.Rural residents with a history of pregnancy loss experienced a 19%and 38%increased risk of breast and cervical cancers,respectively,compared to their urban counterparts.Moreover,a positive graded relationship between live births and pregnancy loss on cervical cancer was observed.What are the implications for public health practice?This study has significant implications for identifying women at an increased risk for breast and genital cancers and contributes to the development of effective public health strategies for female cancer prevention.Future research on reproductive history,particularly in rural areas,should be given priority in efforts to improve female cancer screening and early detection. | Yongle Zhan Yawen Wang Yimin Qu Lin Zhang Xuan Liu Ruiyi Liu Peng Xue Jiaxu Wang Dongxu Qin Hexin Yue Canqing Yu Jun Lyu Yu Guo Zhengming Chen Yu Jiang Liming Li China Kadoorie Biobank Collaborative Group | 2023 | China CDC weekly2023，5，19： | 0 |
| 9 | Visible-light-driven Hydroamination of Alkynes over a New Type of Activated Carbon Immobilized Cu^(2+)Photocatalyst显示文摘A new type of activated carbon immobilized copper(Cu/AC)photocatalyst was prepared by a facile impregnation-adsorption method,where Cu^2+is chemically adsorbed by abundant oxygenated functional groups on large-surface-area activated carbon surface.Cu/AC exhibited good activity and selectivity to imine for the hydroamination of alkynes at 60℃under visible light irradiation.The reaction is initialized by the activation of alkynes molecules at Cu active sites with the aid of light as evidenced by the solid-state NMR and laser photolysis measurements and the control experiments.This strategy for catalyst design is potentially extended to the immobilization of other metal homogeneous catalysts for various heterogeneous catalytic systems. | GU Xianmo MA Pengwei LIU Pei WANG Ruiyi LI Xincheng ZHENG Zhanfeng | 2020 | Chemical Research in Chinese Universities2020，36，6： | 0 |
| 10 | Switching of CO_(2)hydrogenation selectivity via chlorine poisoning over Ru/TiO_(2)catalyst显示文摘It is fascinating to explore the distribution of CO_(2)hydrogenation products regulated by heterogeneous catalysts,as both the chemical state of surface metals and structure of the support itself of the supported catalysts may affect the performance of CO_(2)hydrogenation.Herein,the complete switching of CO_(2)hydrogenation products from CH4 to CO can be realized by induction of Cl into Ru/TiO_(2)catalyst.Density functional theory(DFT)calculations indicated that Cl ions were mainly located on the Ru metal sites of Ru/TiO_(2)catalysts.Bader charge analysis and Ru 3p X-ray photoelectron spectra(XPS)results suggested that electrons transferred from Ru to Cl,resulting in the decrease of electron density of Ru.In situ diffuse reflectance infrared Fourier transform spectroscopy(DRIFTS)of CO_(2)hydrogenation and CO adsorption proved that with the increase of the Cl ion content,the adsorption of CO on the catalyst surface was significantly weakened,and resulted in the high CO selectivity.Our work demonstrates the role of Cl ions in regulating the distribution of CO_(2)hydrogenation products,and provides new ideas for regulating other catalytic processes. | Jin Zhang Mengting Gao Ruiyi Wang Xincheng Li Tianfen Huang Jing Wang Yunwei Wang Zhanfeng Zheng | 2023 | Nano Research2023，16，4： | 0 |
| 11 | Quality of experience evaluation of HTTP video streaming based on user interactive behaviors显示文摘User interactive behaviors play a dual role during the hypertext transfer protocol(HTTP) video service: reflection and influence. However, they are seldom taken into account in practices. To this end, this paper puts forward the user interactive behaviors, as subjective factors of quality of experience(QoE) from viewer level, to structure a comprehensive multilayer evaluation model based on classic network quality of service(QoS) and application QoS. First, dual roles of user behaviors are studied and the characteristics are extracted where the user experience is correlated with user interactive behaviors. Furthermore, we categorize QoE factors into three dimensions and build the metric system. Then we perform the subjective tests and investigate the relationships among network path quality, user behaviors, and QoE. Ultimately, we employ the back propagation neural network(BPNN) to validate our analysis and model. Through the simulation experiment of mathematical and BPNN, the dual effects of user interaction behaviors on the reflection and influence of QoE in the video stream are analyzed, and the QoE metric system and evaluation model are established. | Li Wenjing Yu Peng Wang Ruiyi Feng Lei Dong Ouzhou Qiu Xuesong | 2017 | The Journal of China Universities of Posts and Telecommunications2017，24，3： | 0 |
| 12 | Sensing of cytoplasmic chromatin by cGAS activates innate immune response in SARS-CoV-2 infection显示文摘The global coronavirus disease 2019(COVID-19)pandemic is caused by severe acute respiratory syndrome coronavirus 2(SARSCoV-2),a positive-sense RNA virus.How the host immune system senses and responds to SARS-CoV-2 infection remain largely unresolved.Here,we report that SARS-CoV-2 infection activates the innate immune response through the cytosolic DNA sensing cGAS-STING pathway.SARS-CoV-2 infection induces the cellular level of 2′3′-cGAMP associated with STING activation.cGAS recognizes chromatin DNA shuttled from the nucleus as a result of cell-to-cell fusion upon SARS-CoV-2 infection.We further demonstrate that the expression of spike protein from SARS-CoV-2 and ACE2 from host cells is sufficient to trigger cytoplasmic chromatin upon cell fusion.Furthermore,cytoplasmic chromatin-cGAS-STING pathway,but not MAVS-mediated viral RNA sensing pathway,contributes to interferon and pro-inflammatory gene expression upon cell fusion.Finally,we show that cGAS is required for host antiviral responses against SARS-CoV-2,and a STING-activating compound potently inhibits viral replication.Together,our study reported a previously unappreciated mechanism by which the host innate immune system responds to SARS-CoV-2 infection,mediated by cytoplasmic chromatin from the infected cells.Targeting the cytoplasmic chromatin-cGAS-STING pathway may offer novel therapeutic opportunities in treating COVID-19.In addition,these findings extend our knowledge in host defense against viral infection by showing that host cells’self-nucleic acids can be employed as a“danger signal”to alarm the immune system. | Zhuo Zhou Xinyi Zhang Xiaobo Lei Xia Xiao Tao Jiao Ruiyi Ma Xiaojing Dong Qi Jiang Wenjing Wang Yujin Shi Tian Zheng Jian Rao Zichun Xiang Lili Ren Tao Deng Zhengfan Jiang Zhixun Dou Wensheng Wei Jianwei Wang | 2021 | Signal Transduction and Targeted Therapy2021，6，12： | 0 |
| 13 | Lanthanide-semiconductor probes for precise imaging-guided phototherapy and immunotherapy显示文摘Objective::Immunotherapy is an effective tumor treatment strategy.However,its long treatment cycle limits its wide application across all cancer types.In this study,we optimized upconversion nanoparticles and manganese composite particles with a porous structure as a nanoplatform for synergistic photodynamic therapy(PDT)and photothermal therapy(PTT),and subsequent longer-term immunotherapy.Methods::The morphology,phase,and stability were first characterized to evaluate the biocompatibility of this material.The upconversion and near infrared II luminescence properties of the material and its stimuli-response effect were assessed from the absorbance and photoluminescence spectra.Phototherapy including PDT and PTT was demonstrated in vitro and in vivo,and immunotherapy was used to enhance the phototherapy.This study was approved by the Xi’an Jiaotong University,China(approval No.XJTULAC2020-585)on April 2,2020.Results::The nanoplatform showed good PDT and PTT effects with high upconversion luminescence,and exhibited a more sensitive glutathione response(detection limit:55μg/mL)using fluorescence recovery than that based on absorbance recovery,with the detection range extending up to 1.2 mg/mL.When the surface of the composite particles was modified with an anti-PD-L1 immune checkpoint inhibitor,it targeted A549 lung cancer cells.The resulting immune response enhanced the long-term anti-tumor effect of the therapy,especially in lung cancer patients with high PD-L1 expression.Conclusion::The designed composite can be simultaneously used to detect the glutathione concentration based on luminescence recovery in the tumor cells and as a theranostic nanoplatform for synergistic immuno-phototherapy when combined with an antibody. | Yanxing Wang Weidong Lü Ruiyi Dai Bi Lin Ruichan Lv | 2020 | Journal of Bio-X Research2020，3，4： | 0 |
| 14 | Light-guided tumor diagnosis and therapeutics:From nanoclusters to polyoxometalates显示文摘Malignant tumors,with the characteristics of easy metastasis and recurrence,are a serious threat to health of mankind.It is urgent to develop promising clinical cancer targeted agents with combination of rapid diagnosis and efficient therapies.Compared with the conventional photosensitizing agents,the recent advances of nanoagents based on transition metal-oxide clusters possess unique structural and electronic properties,greatly improving cancer survival rate,meanwhile,keeping high contrast imaging.This review provides a brief introduction of metal-oxide clusters,including both nanoclusters to molecular clusters,specifically polyoxometalates(POMs).Subsequently,biocompatibility of metal-oxide clusters is emphasized from aspects of endocytosis,macropinocytosis,and phagocytosis.Through the classification of late and early transition metals oxide clusters,recent outcomes of light-guided nanoagents are represented with their intriguing chemical and optical properties in their diagnosing and photochemotherapy performance.It shed light on the summary of next generation multifunctional cancer targeting agents'developments as well as outlook of materials selection trends and research direction in the future. | Xiaofeng Fan Wei Pang Hao Feng Ruiyi Zhang Wentao Zhu Qiushi Wang Jun Miao Yiwen Li Yanjun Liu Xiaoqian Xu | 2022 | Chinese Chemical Letters2022，33，6： | 0 |
| 15 | Incidence and risk factors of early transient intraocular pressure elevation after canaloplasty for primary open-angle glaucoma显示文摘Glaucoma is one of the most common optic neuropathies,featuring progressive retinal ganglion cell damage and visual field loss(Tham et al.,2014;Xu et al.,2020).Currently,the only effective treatment for this condition is the reduction of intraocular pressure(IOP)(Palmberg,2001;Heijl et al.,2002).Canaloplasty is a proven bleb-independent surgery with good efficacy and safety profiles in primary open-angle glaucoma(POAG)(Gołaszewska et al.,2021).However,early transient postoperative IOP elevation has been reported in up to 30%of cases(Riva et al.,2019),similar to that commonly observed in other internal drainage glaucoma surgeries such as implantation using iStent(0%–21.0%),CyPass(10.8%),and Hydrus(4.8%–6.5%)(Lavia et al.,2017). | Lijuan XU Xinyao ZHANG Yang CAO Yin ZHAO Juan GU Wenqing YE Xiaojie WANG Jinxin LI Ruiyi REN Yuanbo LIANG | 2023 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2023，24，4： | 0 |
| 16 | Indications,strategies,and development on prostate targeted biopsy:Report of the Panjiayuan Consensus Conference 2022显示文摘Prostate biopsy is the gold standard for diagnosing prostate cancer(PCa).Prostate targeted biopsy(TB)having a higher rate of detecting clinically significant PCa(csPCa)than traditional systematic biopsy(SB)is supported by high-quality evidence.However,the TB indications and strategies are controversial.The National Cancer Center/Cancer Hospital,Chinese Academy of Medical Sciences,invited a panel of recognized urology experts in PCa to address these topics at the Panjiayuan Consensus Conference 2022.The conference results on prostate TB are presented herein.The National Cancer Center/Cancer Hospital,Chinese Academy of Medical Sciences identified 10 key areas of prostate biopsy:(1)selection of imaging examination;(2)indications of TB;(3)transperineal and transrectal prostate biopsy;(4)TB pathways;(5)TB and SB;(6)three techniques of TB;(7)the number of TB cores needed for one lesion;(8)core number for SB;(9)free-hand TB;(10)future development of TB/prostate diagnosis.Thus,a panel of 25 recognized urologists and 2 radiologists from China were invited to attend this conference.The panel voted anonymously on 14 predetermined questions.Voting was based on the panelists'clinical practice and opinion,rather than high-level evidence.The voting outcomes were supported by the panel unequally,and details of the voting results were reported.The voting results can help clinicians to decide on biopsy timing and proper strategies,for which guidelines are sparse.We also focused on the future development of TB and SB,such as the combined pathway of TB and SB,techniques of TB,biopsy cores,free-hand TB,and prostate-specific membrane antigen positron emission tomography/computed tomography. | Gang Song Yajian Li Huimin Hou Yichen Wang Xuejuan Wang Shaoxi Niu Xiang Tu Hongliang Shen Zhien Zhou Yinbing Wang Ruiyi Yan Ning Xu Gejun Zhang Hailong Hao Shudong Zhang Ben Liu Bin Yang Baojun Wang Haifeng Wang Haifeng Huang Qian Zhang Baijun Dong Yonghong Li Jianbin Bi Weigang Yan Hongqian Guo Yuanjie Niu Guosheng Yang Ming Liu Qiang Wei Nianzeng Xing | 2023 | UroPrecision2023，1，1： | 0 |
| 17 | Achieving high dielectric energy-storage properties through a phase coexistence design and viscous polymer process in BNT-based ceramics显示文摘In the last few decades,dielectric capacitors have gotten a lot of attention because they can store more power and charge and discharge very quickly.But it has a low energy-storage density(Wrec),efficiency(h),and temperature stability.By adding Pb(Mg1/3Nb2/3)O3(PMN)and(Bi0$1Sr0.85)TiO3(BST)to a nonstoichiometric(Bi0$51Na0.5)TiO3(BNT)matrix,the goal is to change the phase transition properties and make the material more relaxor ferroelectric(RFE)by lowering the remnant polarization Pr and keeping the maximum polarization Pmax.A viscous polymer process(VPP)is used to improve the electric breakdown strength,which is also a key part of being able to store energy.By working together,ceramics with the formula 0.79[0.85BNT-0.15PMN]-0.21BST(BP-0.21BST)are made.The phase structure has been changed from a rhombohedral phase to a rhombohedral-tetragonal coexisted phase.This is beneficial for RFE properties and gives a Wrec of 6.45 J/cm^(3) and a h of 90%at 400 kV/cm.Also,the energy-storage property is very temperature stable between 30 and 150C.These results show that process optimization and composition design can be used to improve the energy storage properties,and that the dielectric ceramic materials made can be used in high-powder pulse dielectric capacitors. | Yule Yang Juanjuan Wang Ruiyi Jing Wenjing Shi Leiyang Zhang Chao Li Xinyu Zeng Fukang Chen Gang Liu Xiaolian Chao Yan Yan Li Jin | 2023 | Journal of Materiomics2023，9，6： | 0 |
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