|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Bearing characteristics of coal pillars based on modified limit equilibrium theory显示文摘There are two states for the coal-mass on the goaf-side which is in stress equilibrium: the state of limit equilibrium(the bearing stress in the coal-mass equals its ultimate bearing stress) and the state of nonultimate equilibrium(the bearing stress in the coal-mass is less than its ultimate bearing stress). To analyze the bearing characteristics of a coal pillar in the state of limit equilibrium and guide the design of pillar width, we established a mechanical analytical model of the non-ultimate equilibrium zone in the coal-mass on the goaf-side combined with the limit equilibrium theory as well as adopting the methods of theory analysis and mechanical analysis based on the assumption of a state of non-ultimate equilibrium. The width correction coefficient of the limit equilibrium zone has been given. The influence of mining depth, stress concentration coefficient of the surrounding rock, the non-limit strength of the coal-mass and stability of the coal rock interface has been studied. On this basis, we have confirmed that when the width of a longwall mining face roadway protection coal pillar is between 11.6 m and 13.16 m in No. 4 coal seam of Xinrui coal mine in Lvliang in Shanxi province the elastic core region in the coal pillar can be assured and the roadway will be located in the area of lower stress which is outside the peak stress. So the revised width of the limit equilibrium zone is more practical. | Wang Xiangyu Bai Jianbiao Wang Ruofan Sheng Wenlong | 2015 | International Journal of Mining Science and Technology2015，25，6： | 6 |
| 2 | Effects of degradable films with different degradation cycles on soil temperature,moisture and maize yield显示文摘Photo biodegradable film is an ideal degradable mulch film with synergistic effect of photo-degradability and biodegradability.To examine the covering effects of different films,maize was cultivated in the field with three kinds of degradable films(DF)mulching which had different degradation cycles(DF No.1,No.2 and No.3),with common plastic film mulching and no filming mulching(open ground)as comparison.The degradation rates and degrees of degradable films were examined,and the effects of different films on soil temperature,soil moisture,maize yield and relevant characteristics in each treatment were analyzed.The results indicated that the degradable films had good degradability,and the weight loss rate in 100 d for DF No.1,No.2,and No.3 were 22.31%,19.46%,and 15.63%,which were 4.16,3.63,and 2.92 times of the plastic film,respectively.In the early period of maize growth,the degradable films had good warming effects on soil,which were similar with the plastic film.The effect of DF No.2 on soil water conservation was slightly better than that of DF No.1 or No.3,similar with that of the plastic film.The soil water contents in 0-140 cm depths were significantly higher for DF No.2 than that for the open ground(p<0.05).The degradable films could significantly promote the ear development of maize,improve the ear characteristics,shorten the bald tip,and increase kernel number per plant(KNP)and 1000-kernel weight(TKW).The grain yields(GYs)for DF No.2,No.1,and No.3 were significantly improved,with 35.15%,31.35%,and 30.07%higher than that the open ground respectively(p<0.05).With no significant difference between DF and the plastic film,the GY was increased more for DF No.2 than that for DF No.1 and No.3.The degradable films fulfilled successfully all the functions of the plastic film,thus they were recommended as viable option to the plastic film due to their good degradability. | Lixia Shen Yumeng Zhang Yinchao Lan Ruofan Li | 2019 | International Journal of Agricultural and Biological Engineering2019，12，3： | 4 |
| 3 | Methanogenic community dynamics in anaerobic co-digestion of fruit and vegetable waste and food waste显示文摘A lab-scale continuously-stirred tank reactor (CSTR), used for anaerobic co-digestion of fruit and vegetable waste (FVW) and food waste (FW) at different mixture ratios, was operated for 178 days at the organic loading rate of 3 kg VS (volatile solids)/(m3·day). The dynamics of the Archaeal community and the correlations between environmental variables and methanogenic community structure were analyzed by polymerase chain reactions-denaturing gradient gel electrophoresis (PCR-DGGE) and redundancy analysis (RDA), respectively. PCR-DGGE results demonstrated that the mixture ratio of FVW to FW altered the community composition of Archaea. As the FVW/FW ratio increased, Methanoculleus, Methanosaeta and Methanosarcina became the predominant methanogens in the community. Redundancy analysis results indicated that the shift of the methanogenic community was significantly correlated with the composition of acidogenic products and methane production yield. Different mixture ratios of substrates led to different compositions of intermediate metabolites, which may affect the methanogenic community. These results suggested that the analysis of microbial communities could be used to diagnose anaerobic processes. | Jia Lin Jiane Zuo Ruofan Ji Xiaojie Chen Fenglin Liu Kaijun Wang Yunfeng Yang | 2012 | Journal of Environmental Sciences2012，24，7： | 4 |
| 4 | Blocking the butyrate-formation pathway impairs hydrogen production in Clostridium perfringens显示文摘使竞争小径失去活性将改进引起发酵的氢生产由要求厌氧微生物,例如那些类 Clostridium。在我们的以前的学习,当时, l 喂奶脱氢酶在被使失去活性的 Clostridium perfringens W13 的氢收益增加了 44% 与它的原来的紧张 W12 相比。在这研究,我们探索了堵住丁酸盐形成小径是否将增加氢产量。acetyl-CoA acetyltransferase 基因(atoB ) 把第一酶编码为这条小径,它最终形成丁酸盐。Clostridium perfringens W14 和 W15 被分别地在 W13 和 W12 使 atoB 失去活性构造。W14 和 W15 的氢收益分别地是 W13 和 W12 的 44% 那些和 33% 。atoB 的 Inactivation 减少了 pyruvate 合成和它的变换到在异种,和在 W14 和 W15 的增加的乙醇形成的 acetyl-CoA。Proteomic 分析表明涉及丁酸盐形成小径的五蛋白质的表情在 W14 是起来调整的。我们的结果建议那丁酸盐形成缺乏改进了乙醇生产然而并非氢生产,显示为在 C 的氢生产的丁酸盐形成小径的重要性。perfringens。 | Ruisong Yu Ruofan Wang Ting Bi Weining Sun Zhihua Zhou | 2013 | Acta Biochimica et Biophysica Sinica2013，45，5： | 2 |
| 5 | Electrospun Scaff old of Collagen and Polycaprolactone Containing ZnO Quantum Dots for Skin Wound Regeneration显示文摘Nanofibers(NFs)have been widely used in tissue engineering such as wound healing.In this work,the antibacterial ZnO quantum dots(ZnO QDs)have been incorporated into the biocompatible poly(ε-caprolactone)/collagen(PCL/Col)fibrous scaffolds for wound healing.The as-fabricated PCL-Col/ZnO fibrous scaffolds exhibited good swelling,antibacterial activity,and biodegradation behaviors,which were beneficial for the applications as a wound dressing.Moreover,the PCL-Col/ZnO fibrous scaffolds showed excellent cytocompatibility for promoting cell proliferation.The resultant PCL-Col/ZnO fibrous scaffolds containing vascular endothelial growth factor(VEGF)also exhibited promoted wound-healing effect through promoting expression of transforming growth factor-β(TGF-β)and the vascular factor(CD31)in tissues in the early stages of wound healing.This new electrospun fibrous scaffolds with wound-healing promotion and antibacterial property should be convenient for treating wound healing. | Pengfei Li Liming Ruan Ruofan Wang Tianqi Liu Gao Song Xiaofei Gao Guohua Jiang Xiaoyan Liu | 2021 | Journal of Bionic Engineering2021，18，6： | 2 |
| 6 | Robotic Knee Tracking Control to Mimic the Intact Human Knee Profile Based on Actor-Critic Reinforcement Learning显示文摘We address a state-of-the-art reinforcement learning(RL)control approach to automatically configure robotic pros-thesis impedance parameters to enable end-to-end,continuous locomotion intended for transfemoral amputee subjects.Specifically,our actor-critic based RL provides tracking control of a robotic knee prosthesis to mimic the intact knee profile.This is a significant advance from our previous RL based automatic tuning of prosthesis control parameters which have centered on regulation control with a designer prescribed robotic knee profile as the target.In addition to presenting the tracking control algorithm based on direct heuristic dynamic programming(dHDP),we provide a control performance guarantee including the case of constrained inputs.We show that our proposed tracking control possesses several important properties,such as weight convergence of the learning networks,Bellman(sub)optimality of the cost-to-go value function and control input,and practical stability of the human-robot system.We further provide a systematic simulation of the proposed tracking control using a realistic human-robot system simulator,the OpenSim,to emulate how the dHDP enables level ground walking,walking on different terrains and at different paces.These results show that our proposed dHDP based tracking control is not only theoretically suitable,but also practically useful. | Ruofan Wu Zhikai Yao Jennie Si He(Helen)Huang | 2022 | IEEE/CAA Journal of Automatica Sinica2022，9，1： | 1 |
| 7 | HOTAIR enhanced aggressive biological behaviors and induced radio-resistance via inhibiting p21 in cervical cancer显示文摘 | Jing L Yuan W Ruofan D | 2015 | Tumour Biol2015，36，5： | 1 |
| 8 | High-throughput site-specific N-glycoproteomics reveals glyco-signatures for liver disease diagnosis显示文摘The glycoproteome has emerged as a prominent target for screening biomarkers,as altered glycosylation is a hallmark of cancer cells.In this work,we incorporated tandem mass tag labeling into quantitative glycoproteomics by developing a chemical labeling-assisted complementary dissociation method for the multiplexed analysis of intact N-glycopeptides.Benefiting from the complementary nature of two different mass spectrometry dissociation methods for identification and multiplex labeling for quantification of intact N-glycopeptides,we conducted the most comprehensive site-specific and subclass-specific N-glycosylation profiling of human serum immunoglobulin G(IgG)to date.By analysing the serum of 90 human patients with varying severities of liver diseases,as well as healthy controls,we identified that the combination of IgG1-H3N5F1 and IgG4-H4N3 can be used for distinguishing between different stages of liver diseases.Finally,we used targeted parallel reaction monitoring to successfully validate the expression changes of glycosylation in liver diseases in a different sample cohort that included 45 serum samples. | Zhenyu Sun Bin Fu Guoli Wang Lei Zhang Ruofan Xu Ying Zhang Haojie Lu | 2023 | National Science Review2023，10，1： | 1 |
| 9 | HOTAIR enhanced aggressive biologi- cal behaviors and induced radio-resistance via inhibiting p21 in cer- vical cancer显示文摘 | Jing L Yuan W Ruofan D | 2015 | Tumour Bioi2015，36，5： | 1 |
| 10 | A Meta-Analysis of Randomized Controlled Trials Comparing Irinotecan/Platinum with Etoposide/Platinum in Patients with Previously Untreated Extensive-Stage Small Cell Lung Cancer显示文摘 | Jingwei Jiang Xiaohua Liang Xinli Zhou Lizhen Huang Ruofan Huang Zhaohui Chu Qiong Zhan | 2010 | Journal of Thoracic Oncology2010，，6： | 1 |
| 11 | Gefitinib versus docetaxel in previously treated advanced non-small-cell lung cancer: A meta-analysis of randomized controlled trials显示文摘 | Jingwei Jiang Lizhen Huang Xiaohua Liang Xinli Zhou Ruofan Huang Zhaohui Chu Qiong Zhan | 2011 | Acta Oncologica2011，，4： | 1 |
| 12 | Brain metastases as the first symptom of lung cancer: a clinical study from an Asian medical center显示文摘 | Jia Jin Xinli Zhou Xiaohua Liang Ruofan Huang Zhaohui Chu Jingwei Jiang Qiong Zhan | 2013 | Journal of Cancer Research and Clinical Oncology2013，，3： | 1 |
| 13 | H O T A I R enhanced aggressivebiological behaviors and induced radio-resistancevia inhibiting p21 in cervical cancer 显示文摘 | Jing L Y u a n W Ruofan D | 2015 | T u m o u r Biol2015，36，5： | 1 |
| 14 | Influence of abnormal stress under a residual bearing coal pillar on the stability of a mine entry显示文摘Mine entries close to residual bearing coal pillars(RBCPs) will suffer large deformation that may cause rock burst. To better understand the deformation mechanism and develop safe and practical guidelines for entry design, most studies focus on the absolute size of the stress field in and around the pillar. In this paper, we present a new approach to analyze the abnormal stress field close to a RBCP that uses the stress concentration coefficient(SCC), stress gradient(SG), and coefficient of lateral pressure(CLP) to describe the stress state induced by the RBCP. Based on elastic theory and a mathematical model for the abutment stress in the RBCP, an analytical solution for the abnormal stress in the strata below the RBCP was derived and the characteristics of the abnormal stress for a case study of a coal mine in China were analyzed. The results show that the abnormal stress field around the pillar is characterized by four distinct zones: a zone of high SCC, high SG, and CLP less than 1, a zone of high SCC, low SG, and CLP less than 1, a zone of low SCC, SG close to 0, and CLP greater than 1, and a zone of SCC close to 1, SC close to 0, and CLP close to 1. Based on this zoning pattern, a numerical model was established to study the combined effects of the abnormal stress on the stability of the entry. The most stable zone was determined based on a model of the Xinrui coal mine and verified by field measurements at the mine. Our conclusions can be used as guidelines for designing safe entry layouts in similar geological and mining settings. | Kang Jizhong Shen Wenlong Bai Jianbiao Yan Shuai Wang Xiangyu Li Wenfeng Wang Ruofan | 2017 | International Journal of Mining Science and Technology2017，27，6： | 1 |
| 15 | A three-dimensional polycyclic aromatic hydrocarbon based covalent organic framework doped with iodine for electrical conduction显示文摘Covalent organic frameworks(COFs) are a class of crystalline porous organic materials with variable structures and fascinating properties. The intrinsic low conductivity impedes their widely application in optoelectronic. Iodine doping is an effective way to enhance the electrical conductivity of COFs. Here, a novel 3D imine COF with lvt topology is synthesized from two different pentacene derivatives with the same core in the form of structural complementarity. DDHP-COF is a highly crystalline material featuring high surface area of 1679 m^(2)/g and excellent thermal stability up to 490 ℃. Upon doping with iodine, the electrical conductivity can reach as high as 1.5×10^(-2)S/m which is significantly enhanced over 6 orders of magnitude compared with the pristine COF. | Ruofan Li Guolong Xing Hui Li Shen Li Long Chen | 2023 | Chinese Chemical Letters2023，34，4： | 0 |
| 16 | A metabolite from commensal Candida albicans enhances the bactericidal activity of macrophages and protects against sepsis显示文摘The gut microbiome is recognized as a key modulator of sepsis development.However,the contribution of the gut mycobiome to sepsis development is still not fully understood.Here,we demonstrated that the level of Candida albicans was markedly decreased in patients with bacterial sepsis,and the supernatant of Candida albicans culture significantly decreased the bacterial load and improved sepsis symptoms in both cecum ligation and puncture(CLP)-challenged mice and Escherichia coli-challenged pigs.Integrative metabolomics and the genetic engineering of fungi revealed that Candida albicans-derived phenylpyruvate(PPA)enhanced the bactericidal activity of macrophages and reduced organ damage during sepsis.Mechanistically,PPA directly binds to sirtuin 2(SIRT2)and increases reactive oxygen species(ROS)production for eventual bacterial clearance.Importantly,PPA enhanced the bacterial clearance capacity of macrophages in sepsis patients and was inversely correlated with the severity of sepsis in patients.Our findings highlight the crucial contribution of commensal fungi to bacterial disease modulation and expand our understanding of the host-mycobiome interaction during sepsis development. | Peng Gu Ruofan Liu Qin Yang Li Xie Rongjuan Wei Jiaxin Li Fengyi Mei Tao Chen Zhenhua Zeng Yan He Hongwei Zhou Hongjuan Peng Kutty Selva Nandakumar Huikuan Chu Yong Jiang Wei Gong Ye Chen Bernd Schnabl Peng Chen | 2023 | Cellular & Molecular Immunology2023，20，10： | 0 |
| 17 | Aptamer-based cell-free detection system to detect target protein显示文摘Biomarkers of disease,especially protein,show great potential for diagnosis and prognosis.For detecting a certain protein,a binding assay implementing antibodies is commonly performed.However,antibodies are not thermally stable and may cause false-positive when the sample composition is complicated.In recent years,a functional nucleic acid named aptamer has been used in many biochemical analysis cases,which is commonly selected from random sequence libraries by using the systematic evolution of ligands by exponential enrichment(SELEX)techniques.Compared to antibodies,the aptamer is more thermal stable,easier to be modified,conjugated,and amplified.Herein,an Aptamer-Based Cell-free Detection(ABCD)system was proposed to detect target protein,using epithelial cell adhesion molecule(EpCAM)as an example.We combined the robustness of aptamer in binding specificity with the signal amplification ability of CRISPR-Cas12a′s trans-cleavage activity in the ABCD system.We also demonstrated that the ABCD system could work well to detect target protein in a relatively low limit of detection(50-100 nM),which lay a foundation for the development of portable detection devices.This work highlights the superiority of the ABCD system in detecting target protein with low abundance and offers new enlightenment for future design and development. | Junhong Chen Xiaoyan Zhuang Jiyang Zheng Ruofan Yang Fei Wu Aihui Zhang Baishan Fang | 2021 | Synthetic and Systems Biotechnology2021，6，3： | 0 |
| 18 | Experimental Study on the Axial Compression Behavior of Short Columns of Steel-Fiber-Reinforced Recycled Aggregate Concrete显示文摘In order to study the axial compression performances of short columns made of recycled aggregate concrete,four samples were designed with different recycled aggregate replacement rates and carbon fibre reinforced plastics(CFRP)sheets.Then,monotonic loading was implemented to assess the variation trends of their axial compression properties.The ABAQUS finite element software was also used to determined the compression performances.Good agreement between experimental and numerical results has been found for the different parameters being considered.As shown by the results,recycled coarse aggregates result in improved ductility and better deformation performance of the specimens.The failure of specimens caused by pre damage can be compensated by using CFRP sheets,by which both the resistance to deformation and the axial carrying capacity of columns can be increased. | Chunyang Liu Jia Xu Yifan Gu Ruofan Shi | 2021 | Fluid Dynamics & Materials Processing2021，17，6： | 0 |
| 19 | Corrigendum to“Aptamer-based cell-free detection system to detect target protein”[Synth Syst Biotechnol 6(3)(2021)209–215]显示文摘The authors regret that following the publication of the original article,the authors noticed that the“Affiliation a”were incorrect.It should be“XMU-China Team,College of Chemistry and Chemical Engineering,Xiamen University,Xiamen,361005,PR China”. | Junhong Chen Xiaoyan Zhuang Jiyang Zheng Ruofan Yang Fei Wu Aihui Zhang Baishan Fang | 2023 | Synthetic and Systems Biotechnology2023，8，2： | 0 |
| 20 | Relationship between thyroid hormones and metabolic syndrome in a normal thyroid function population in Western China:a cross-sectional study based on both epidemiological and genetic analysis显示文摘To the Editor:Metabolic syndrome(MetS)is defined as a set of metabolic disorders including abdominal obesity,hyperglycemia,hypertension,and dyslipidemia.[1]As thyroid hormones are essential for cellular energy homeostasis and regulation,the levels of serum thyroid hormones are considered to be associated with various metabolic parameters.Over the past decade,the association between thyroid hormones and MetS has been extensively studied in euthyroid subjects,leading to inconsistent results.Some studies suggested that a high level of thyrotropin(TSH)contributed to the increased incidence of MetS or unfavorable metabolic parameters,whereas other studies found no such correlation.Moreover,some researches have shown that free thyroxin(FT4)levels were inversely proportional to various unfavorable metabolic parameters or MetS,while other studies suggested that FT4 levels have no such association or even a positive association with some unfavorable metabolic components after adjustment.These conflicting results may result from different designs,settings,race,exclusion criteria,adjustments,statistical analyses,and definitions of MetS and population iodine intake.Based on these,our study aimed to evaluate the association and causal relationship between thyroid hormones and MetS in people with normal thyroid function through standard epidemiological and Mendelian randomization analysis. | Shengru Liang Jing Cai Yang Yang Lei Zhang Peter Taylor Jie Ming Xinwen Yu Ruofan Hu Jie Zhou Colin M.Da-Yan Qiuhe Ji | 2022 | Chinese Medical Journal2022，，3： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员