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| 1 | Cerebral small vessel disease or intracranial large vessel atherosclerosis may carry different risk for future strokes显示文摘Background The effect of cerebral small vessel disease(CSVD)and intracranial arterial stenosis(ICAS)on stroke outcomes remains unclear.Methods Data of 1045 patients with minor stroke or transient ischaemic attack(TIA)were obtained from 45 sites of the Clopidogrel in High-Risk Patients with Acute Non-disabling Cerebrovascular Events(CHANCE)trial.We assessed the associations of burdens of CSVD and ICAS with new strokes and bleeding events using multivariate Cox regression models and those with modified Rankin Scale(mRS)scores using ordinal logistic regression models.Results Among the 1045 patients,CSVD was present in 830 cases(79.4%)and ICAS in 460(44.0%).Patients with>1 ICAS segment showed the highest risk of new strokes(HR 2.03,95%CI 1.15 to 3.56,p=0.01).No association between CSVD and the occurrence of new strokes was found.The presence of severe CSVD(common OR(cOR)2.01,95%CI 1.40 to 2.89,p<0.001)and>1 ICAS segment(cOR 2.15,95%CI 1.57 to 2.93,p<0.001)was associated with higher mRS scores.Severe CSVD(HR 10.70,95%CI 1.16 to 99.04,p=0.04),but not ICAS,was associated with a higher risk of bleeding events.Six-point modified CSVD score improved the predictive power for bleeding events and disability.Interpretation CSVD is associated with more disability and bleeding events,and ICAS is associated with an increased risk of stroke and disability in patients with minor stroke and TIA at 3 months.CSVD and ICAS may represent different vascular pathologies and play distinct roles in stroke outcomes. | Huimin Chen Yuesong Pan Lixia Zong Jing Jing Xia Meng Yuyuan Xu Hongyi Yan Xingquan Zhao Liping Liu Hao Li S Claiborne Johnston Yongjun Wang Yilong Wang | 2020 | Stroke & Vascular Neurology2020，5，2： | 13 |
| 2 | Validation and refinement of scores to predict very early stroke risk after transient ischaemic attack显示文摘 | S Claiborne Johnston Peter M Rothwell Mai N Nguyen-Huynh Matthew F Giles Jacob S Elkins Allan L Bernstein Stephen Sidney | 2007 | 2007 (9558)2007，，9558： | 3 |
| 3 | Validation and refinement of scores to predict very early stroke risk after transient ischaemic attack显示文摘 | S Claiborne Johnston Peter M Rothwell Mai N Nguyen-Huynh Matthew F Giles Jacob S Elkins Allan L Bernstein Stephen Sidney | 2007 | The Lancet . 2007 (9558)2007，，9558： | 2 |
| 4 | Validation and refinement of scores to predict very early stroke risk after transient ischaemic attack显示文摘 | S Claiborne Johnston Peter M Rothwell Mai N Nguyen-Huynh Matthew F Giles Jacob S Elkins Allan L Bernstein Stephen Sidney | 2007 | The Lancet2007，，9558： | 2 |
| 5 | Longitudinal risk of intracranial hemorrhage in patients with arteriovenous malfomation of the brain within a defined population显示文摘 | Halim Alexander X Johnston S Claiborne Singh Vineeta | 2004 | Stroke2004，35，： | 1 |
| 6 | Incomplete Inhibition of Thromboxane Biosynthesis by Acetylsalicylic Acid: Determinants and Effect on Cardiovascular Risk显示文摘 | John W. Eikelboom Graeme J. Hankey Jim Thom Deepak L. Bhatt P Gabriel Steg Gilles Montalescot S Claiborne Johnston Steven R. Steinhubl Koon-Hou Mak J Donald Easton Christian Hamm Tingfei Hu Keith A.A. Fox Eric J. Topol | 2008 | Circulation2008，，17： | 1 |
| 7 | Definition and Evaluation of Transient Ischemic Attack: A Scientific Statement for Healthcare Professionals From the American Heart Association/American Stroke Association Stroke Council; Council on Cardiovascular Surgery and Anesthesia; Council on Cardio显示文摘 | J Donald Easton Jeffrey L. Saver Gregory W. Albers Mark J. Alberts Seemant Chaturvedi Edward Feldmann Thomas S. Hatsukami Randall T. Higashida S Claiborne Johnston Chelsea S. Kidwell Helmi L. Lutsep Elaine Miller Ralph L. Sacco | 2009 | Stroke2009，，6： | 1 |
| 8 | Tumor Necrosis Factor-α–238G>A Promoter Polymorphism Is Associated With Increased Risk of New Hemorrhage in the Natural Course of Patients With Brain Arteriovenous Malformations显示文摘 | Achal S. Achrol Ludmila Pawlikowska Charles E. McCulloch K Y. Trudy Poon Connie Ha Jonathan G. Zaroff S Claiborne Johnston Chanhung Lee Michael T. Lawton Stephen Sidney Douglas A. Marchuk Pui-Yan Kwok William L. Young | 2006 | Stroke2006，，1： | 1 |
| 9 | Update to the AHA/ASA Recommendations for the Prevention of Stroke in Patients With Stroke and Transient Ischemic Attack显示文摘 | Robert J. Adams Greg Albers Mark J. Alberts Oscar Benavente Karen Furie Larry B. Goldstein Philip Gorelick Jonathan Halperin Robert Harbaugh S Claiborne Johnston Irene Katzan Margaret Kelly-Hayes Edgar J. Kenton Michael Marks Ralph L. Sacco Lee H. Schwamm | 2008 | Stroke2008，，5： | 1 |
| 10 | Significance of Large Vessel Intracranial Occlusion Causing Acute Ischemic Stroke and TIA显示文摘 | Wade S. Smith Michael H. Lev Joey D. English Erica C. Camargo Maggie Chou S Claiborne Johnston Gilberto Gonzalez Pamela W. Schaefer William P. Dillon Walter J. Koroshetz Karen L. Furie | 2009 | Stroke2009，，： | 1 |
| 11 | Clinical- and Imaging-Based Prediction of Stroke Risk After Transient Ischemic Attack: The CIP Model显示文摘 | Hakan Ay E Murat Arsava S Claiborne Johnston Mark Vangel Lee H. Schwamm Karen L. Furie Walter J. Koroshetz A Gregory Sorensen | 2009 | Stroke2009，，1： | 1 |
| 12 | Longitudinal risk of intracranial hemorrhage in patients with arteriovenous malformation of the brain within a defined population显示文摘 | Johnston S Claiborne Singh Vineeta | 2004 | Stroke2004，35，： | 1 |
| 13 | Clinical- and Imaging-Based Prediction of Stroke Risk After Transient Ischemic Attack: The CIP Model显示文摘 | Hakan Ay E Murat Arsava S Claiborne Johnston Mark Vangel Lee H. Schwamm Karen L. Furie Walter J. Koroshetz A Gregory Sorensen | 2009 | Stroke2009，，1： | 1 |
| 14 | Update to the AHA/ASA Recommendations for the Prevention of Stroke in Patients With Stroke and Transient Ischemic Attack显示文摘 | Robert J. Adams Greg Albers Mark J. Alberts Oscar Benavente Karen Furie Larry B. Goldstein Philip Gorelick Jonathan Halperin Robert Harbaugh S Claiborne Johnston Irene Katzan Margaret Kelly-Hayes Edgar J. Kenton Michael Marks Ralph L. Sacco Lee H. Schwamm | 2008 | Stroke2008，，5： | 1 |
| 15 | Trends in Usage of Alternative Antiplatelet Therapy After Stroke and Transient Ischemic Attack显示文摘 | Nancy K. Hills S Claiborne Johnston | 2008 | Stroke2008，，4： | 1 |
| 16 | How Accurate Is CT Angiography in Evaluating Intracranial Atherosclerotic Disease?显示文摘 | Mai N. Nguyen-Huynh Max Wintermark Joey English Jack Lam Eric Vittinghoff Wade S. Smith S Claiborne Johnston | 2008 | Stroke2008，，4： | 1 |
| 17 | Update to the AHA/ASA Recommendations for the Prevention of Stroke in Patients With Stroke and Transient Ischemic Attack显示文摘 | Robert J. Adams Greg Albers Mark J. Alberts Oscar Benavente Karen Furie Larry B. Goldstein Philip Gorelick Jonathan Halperin Robert Harbaugh S Claiborne Johnston Irene Katzan Margaret Kelly-Hayes Edgar J. Kenton Michael Marks Ralph L. Sacco Lee H. Schwamm | 2008 | Stroke2008，，5： | 1 |
| 18 | Midlife cardiovascular risk factors and risk of dementia in late life显示文摘 | R A. Whitmer S Sidney J Selby S Claiborne Johnston K Yaffe | 2005 | Neurology2005，，2： | 1 |
| 19 | How Accurate Is CT Angiography in Evaluating Intracranial Atherosclerotic Disease?显示文摘 | Mai N. Nguyen-Huynh Max Wintermark Joey English Jack Lam Eric Vittinghoff Wade S. Smith S Claiborne Johnston | 2008 | Stroke2008，，4： | 1 |
| 20 | A comparison of risk factors for recurrent TIA and stroke in patients diagnosed with TIA 显示文摘 | Claiborne - Johnston SC Sidney S Bernstein A1 | 2003 | Neurology2003，60，2： | 1 |
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